openwiki-wiki/sources/git-repo.md

---
type: "Reference"
title: "Git repo — evidence index (Obsidian vault, Robin)"
description: "Compact manifest of Robin's Obsidian vault + the local OpenWiki wiki, ingested through the local git-repo connector. Two configured repos: obsidian-vault at /home/ldw/workspace (main branch, HEAD a4fa5a32, 2026-08-16, 7 new vault commits in the 2026-08-15T18:07Z → 2026-08-17T18:09Z 48-hour window) and openwiki-wiki at /home/ldw/.openwiki/wiki (main branch, HEAD be49285, 2026-08-17). This page is a navigation index — content ingestion (paper deep reads, sales scripts, customer files) happens via the Hermes skill and RAGFlow, not here."
resource: "~/.openwiki/connectors/git-repo/config.json"
tags: [git-repo, evidence, vault, openwiki-wiki, source, 2026-08-17, 2026-08-15, 2026-08-13]
timestamp: 2026-08-17T18:09:32Z
---

# Git repo — evidence index (Obsidian vault + OpenWiki wiki)

Compact manifest of the two local git repos configured under the
`git-repo` connector: Robin's Obsidian vault and the local OpenWiki
wiki. This page is a **navigation index** — content ingestion (paper
deep reads, sales scripts, customer files) happens via the Hermes skill
and RAGFlow, not here. Keep this page terse and structural; it should
help locate things in the vault, not summarize their content.

## Connector

- **Source instance:** `git-repo-1` (configured under
  `~/.openwiki/connectors/git-repo/config.json`)
- **Configured repos:**
  - `obsidian-vault` → `/home/ldw/workspace` (Robin Obsidian vault, on
    `main`, HEAD `a4fa5a323d6dcabeb9eccad49e636ee6ba5f87a6` as of
    2026-08-16 +0800 — 7 new vault commits in the
    2026-08-15T18:07Z → 2026-08-17T18:09Z 48-hour window: the 2026-08-16
    **Quintard 2024 Nat Commun 4-commit LDR cycle** (`0fc8db24` adds
    file 189 lines → `290e9635` -v2 修图床/双 H1/落款 → `24c713de`
    -v3 Wiki.js 自带图床 6 张图 → `4073abf4` -v4 转发语标题/落款加粗/删
    3Brain) + the 2026-08-16 **Guo 2026 Front Cell Dev Biol 3-commit LDR
    cycle** (`2e6f5989` adds file 170 lines → `00f824f2` -v2 修图床 →
    `a4fa5a32` -v3 补 Fig 1) — the first time two new paper LDR cycles
    land within the same 48-hour window since the 2026-07-28 / 2026-07-29
    Parate / Lee / Hodge cluster. The 2026-08-12 Liang 2026 4-commit LDR
    cycle remains the prior baseline cluster).
  - `openwiki-wiki` → `/home/ldw/.openwiki/wiki` (the OpenWiki knowledge
    base itself, on `main`, HEAD `be4928553364a654b888807a44438b738072c2ce`
    as of 2026-08-17T +0800 — 4 new wiki-side commits in the
    2026-08-15T18:07Z → 2026-08-17T18:09Z window: `151d22b` daily
    update 2026-08-16 + `997b648` sources-sync 2026-08-16 + `5c70881`
    daily update 2026-08-17 + `be49285` sources-sync 2026-08-17; the
    `5c70881` daily update also created the new `sources/openwiki-version-drift.md`
    auto-generated page).
- **Auth:** local paths only — no remote, no credentials.
- **Latest fetch:** `2026-08-17T18:09:32Z` (raw manifest
  `~/.openwiki/connectors/git-repo/raw/2026-08-17T18-09-32-895Z/manifest.json`).
- **Source config:** `~/.openwiki/connectors/git-repo/config.json`
- **State:** `~/.openwiki/connectors/git-repo/state.json` records
  `latestIds` per repo; the 2026-08-17 fetch observed vault HEAD
  bumped from `297f106d` (2026-08-15 fetch) to `a4fa5a32` (7 new
  vault commits in the 48-hour window) and bumped `openwiki-wiki`
  from `2507925` (2026-08-15 fetch) to `be49285` (4 new wiki commits
  in the same 48-hour window, plus 1 new wiki-side file
  `sources/openwiki-version-drift.md`).

## obsidian-vault — working-tree status (2026-08-17)

- **Branch:** `main`
- **HEAD:** `a4fa5a323d6dcabeb9eccad49e636ee6ba5f87a6` (vault HEAD
  **bumped** from `297f106d` across the 2026-08-17 fetch — **7 new
  commits** in the 2026-08-15T18:07Z → 2026-08-17T18:09Z 48-hour
  window: the 2026-08-16 **Quintard 2024 Nat Commun 4-commit LDR cycle**
  + the 2026-08-16 **Guo 2026 Front Cell Dev Biol 3-commit LDR cycle**.
  Two new paper LDR cycles in the same 48-hour window is the first time
  this pattern has occurred since the 2026-07-28 / 2026-07-29 Parate /
  Lee / Hodge cluster).
- **Ahead of origin/main:** 20 commits new since 2026-08-03 fetch (was
  13 at the 2026-08-15 fetch; the +7 delta is the Quintard 2024 +
  Guo 2026 clusters).
- **Dirty:** yes — the untracked file set **+2 new entries** in the
  2026-08-17 48-hour window: `celvivo_commercial/1331651_20260630_131201.pdf`
  (the 6-30 quote PDF, moved into a new folder) + `templates/类器官IRB申请清单.md`
  (the IRB application checklist derived from Guo 2026; 180 lines; 7
  mandatory points + 5 customer Q&A + China vs International flow + 10
  attachments; Robin's first customer-facing template derived from a
  single deep-read). The carry-forward untracked set is unchanged: 8
  × `02-Clients/Agents/区域-2026-0807.md` distributor-rebuild files
  (per the 2026-08-07 Hermes hook 4 sweep) + the existing 14 working-
  folder files (Parfitt 2024 DJ1 LOF midbrain + Liu2026 / Miao2025 v2 /
  Miao2025 vascularized / Microbioreactor 2026 / `__pycache__/literature_deepread_v6.cpython-312.pyc`
  / `dify精读进度-20260805.md` / `literature_deepread_v6.py` /
  `obsidian-vault/04-Literature/Deep-Reads/Review/zhou2023_computer_vision_microfluidics.md`
  / `obsidian-vault/rustdesk-selfhosted-2026-08-05.md` /
  `retinal_organoid_deep_read_2026-08-07.md` / `文悦精读流水线.yml` + v2/v3/v4/v5-clean
  variants). The **`Review/zhou2023_computer_vision_microfluidics.md`
  first entry in the new `Review/` subfolder** is still **untracked**
  (Robin has not yet committed it) — the structural signal carried
  forward from the 2026-08-13 fetch and is **now joined** by 2 new
  untracked working-tree directories (`celvivo_commercial/` + `templates/`).
- **Working-tree status (raw manifest, abbreviated):**

  | Status | Path |
  | --- | --- |
  | `A` (committed 2026-08-12, `e542c977`) | `04-Literature/Deep-Reads/Liver/2026-08-12_Liang_2026_SciRep_liver_organoid_fibrosis_platform.md` — **NEW external evidence** (Liang Y et al. Sci Rep 2026 DOI 10.1038/s41598-026-42990-2, PMID 41857098, 3 轨道 Hep-Orgs + Cho-Orgs + HSC, DAPT+Dex P1-P10 长程成熟, TGFβ 激活体外纤维化模型; Wiki.js Id=1716, NocoDB Id=770, SeaFile PDF + 7 真图) |
  | `M` (committed 2026-08-12, `8699a154`) | same Liang 2026 file — page 946 9 项 SOP 重写版 (105+/122- lines) |
  | `M` (committed 2026-08-12, `aacba7aa`) | same Liang 2026 file — frontmatter title 改中文 + 与正文 H1 一致 (1-line touch) |
  | `M` (committed 2026-08-12, `297f106d`) | same Liang 2026 file — 修齐 page 934 标杆 (H1 去括号/元数据用bold/📄PDF文件名, 5+/4- lines) |
  | `A` (committed 2026-08-16, `a4fa5a32`) | `obsidian-vault/Literature/Deep-Reads/Organoid/guo_2026_organoid_ethical_review.md` — **NEW external evidence** (Guo Z, Zhang N 2026 Front Cell Dev Biol DOI 10.3389/fcell.2026.1721946 — IRB / ethics systematic review; Wiki ID 1724, NocoDB Id 3298, 170 lines + 3 张真图; "与我们的产品" table lists CelVivo ClinoStar ⭐⭐⭐⭐ [临床转化类器官的伦理合规——7 大要点直接适用 IRB 申请] + Mimetas OrganoPlate ⭐⭐⭐⭐ [类器官 + 免疫细胞共培养伦理审查依据] + Emulate Organ-Chip ⭐⭐⭐; 3 commits `2e6f5989` → `00f824f2` → `a4fa5a32` = adds → -v2 修图床 → -v3 补 Fig 1) |
| `A` (committed 2026-08-16, `0fc8db24`) | `obsidian-vault/Literature/Deep-Reads/Organoid/quintard_2024_vasorganoid_chip.md` — **NEW external evidence** (Quintard C et al. 2024 Nat Commun DOI 10.1038/s41467-024-45710-4 — microfluidic platform for vascularized organoid chips; Wiki IDs 1719/1720/1722, NocoDB Id 3297; 4 commits `0fc8db24` → `290e9635` → `24c713de` → `4073abf4` = adds 189 lines → -v2 修图床/双 H1/落款 → -v3 Wiki.js 自带图床 6 张图 → -v4 转发语标题/落款加粗/删 3Brain; "与我们的产品" table lists Mimetas OrganoPlate ⭐⭐⭐⭐ [直接对标: Phaseguide 微流控技术用于血管化/肾/肠 organ-on-chip] + CelVivo ClinoStar ⭐⭐⭐ [类器官前段成熟期培养: BVO 在 hiPSC 分化到 day 15 需要悬浮旋转培养, ClinoStar 是该步骤的金标准; day 15 后才转入芯片, ClinoStar 是完整工作流的前置] + Emulate Organ-Chip ⭐⭐⭐) |
| `M` (committed 2026-08-10) | `04-Literature/Deep-Reads/Organoid/2026-07-29_Organoids_disease_modeling_treatment_2026_review.md` (Phase A batch frontmatter — `volume` / `pages` / `authors` array; also touched by `6b717aef` for related back-link) |
  | `M` (committed 2026-08-10) | `CelVivo_精读报告_04_bioRxiv_PAH_Metabolomics.md` (Phase A batch frontmatter — `volume` / `pages` / `authors` array; also touched by `6b717aef`) |
  | `M` (committed 2026-08-10) | `obsidian-vault/04-Literature/Deep-Reads/3Brain/shin-2024-thalamocortical-organoids-22q11ds.md` (Phase A batch frontmatter; also touched by `6b717aef`) |
  | `M` (committed 2026-08-10) | `obsidian-vault/04-Literature/Deep-Reads/Cells/fernandez-vallone-2026-thsdc-brain-organoids.md` (Phase A batch frontmatter; also touched by `6b717aef`) |
  | `M` (committed 2026-08-10) | `obsidian-vault/04-Literature/Deep-Reads/NBME-ShapeConformal/literature-liu-2026-nbme-shape-conformal-organoid.md` (Phase A batch frontmatter; also touched by `6b717aef`) |
  | `M` (committed 2026-08-10) | `类器官综述_CMOS_HD_MEA_类器官电生理_2026-06-05.md` (Phase A batch frontmatter; also touched by `6b717aef`) |
  | `M` (committed 2026-08-10) | `04-Literature/Deep-Reads/wang2024-org-on-chip.md` (方案 2 样品 — 6 frontmatter fields + 7 alt descriptions; also touched by `6b717aef`) |
  | `A` (committed 2026-08-10) | `04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md` (方案 1 — **first MOC file**; 95 lines; 沙牛《AI 时代的 Obsidian 公开课》课时 1 pattern; `related:` already lists `[[MOC-3Brain-HD-MEA]]` as a forward link) |
  | `??` (untracked) | `02-Clients/Agents/全国经销商地图-2026-0807.md` + 7 区域 `*2026-0807.md` files (8-07 distributor baseline refresh — see below) |
  | `??` (untracked, **NEW 2026-08-17**) | `celvivo_commercial/1331651_20260630_131201.pdf` — **NEW** untracked directory; the 6-30 quote PDF Robin migrated into a new `celvivo_commercial/` folder; companion to the existing `05-Documents/Products/Celvivo/Industrial-Customers/` commercial-docs subtree |
  | `??` (untracked, **NEW 2026-08-17**) | `templates/类器官IRB申请清单.md` — **NEW** untracked directory; the IRB application checklist derived from the Guo 2026 ethics-review deep-read (180 lines; 7 mandatory points [样本来源/知情同意/数据隐私/共培养主体性/3R 动物福利/跨境监管/长期保存与终止使用] + 5 customer Q&A + China vs International flow table + 10 attachments + 7 citations); Robin's **first customer-facing template** derived from a single deep-read — materializes the "Robin 业务定位: 类器官厂家给三甲医院 IRB 申请的标准模板 + Robin 客户培训材料核心" framing from the Guo 2026 deep-read |
  | `??` (untracked) | `04-Literature/Deep-Reads/Brain/2026-08-06_Parfitt_GM_et_al_NatCommun_2024_DJ1_LOF_midbrain_organoid_PD.md` |
  | `??` (untracked) | `Liu2026_NBME_shape_conformal_organoid.md` |
  | `??` (untracked) | `Miao2025_Cell_v2.md` |
  | `??` (untracked) | `Miao2025_Cell_vascularized_organoid.md` |
  | `??` (untracked) | `Microbioreactor_2026_Rosero_FrontBioeng.md` |
  | `??` (untracked) | `__pycache__/literature_deepread_v6.cpython-312.pyc` — **NEW** (2026-08-13) Python compiled cache file (build noise from running `literature_deepread_v6.py`, ignored) |
  | `??` (untracked) | `dify精读进度-20260805.md` |
  | `??` (untracked) | `literature_deepread_v6.py` |
  | `??` (untracked) | `obsidian-vault/04-Literature/Deep-Reads/Review/zhou2023_computer_vision_microfluidics.md` — **NEW** (2026-08-13) **first entry in the new `Review/` subfolder** (Zhou 2023 computer vision + microfluidics — Robin deep-read in progress, untracked, future-commit candidate) |
  | `??` (untracked) | `obsidian-vault/rustdesk-selfhosted-2026-08-05.md` |
  | `??` (untracked) | `retinal_organoid_deep_read_2026-08-07.md` |
  | `??` (untracked) | `文悦精读流水线.yml` + v2/v3/v4/v5-clean variants |

  The 8 untracked `*2026-0807.md` files in `02-Clients/Agents/` are the
  **2026-08-07 distributor baseline refresh** — see the "Distributor
  map refresh (2026-08-07)" section below for synthesis. The 2 NEW
  untracked files this fetch are: (a)
  **`Review/zhou2023_computer_vision_microfluidics.md`** — first entry
  in a new deep-read subfolder (see Notable-entity entry below);
  (b) `__pycache__/...pyc` — build noise, ignored.

### Recent commits (latest first)

| Date | Hash | Note |
| --- | --- | --- |
| 2026-08-16 | `a4fa5a32` | **literature: review 类 Guo 2026 -v3 补 Fig 1** — in-place update ID 1724, 3 张图全 |
| 2026-08-16 | `00f824f2` | **literature: review 类 Guo 2026 -v2 修图床** — in-place update ID 1724, 加 2 张 Wiki.js 自带图 |
| 2026-08-16 | `2e6f5989` | **literature: 精读 Guo 2026 Front Cell Dev Biol - 类器官伦理审查** (review 类, Wiki ID 1724, NocoDB Id 3298) — **NEW external evidence** (类器官研究 IRB / 伦理审查 7 大强制要点系统综述, 嘉兴市第一医院 + 嘉兴大学医学院视角) |
| 2026-08-16 | `4073abf4` | **literature: 精读 Quintard 2024 -v4** — 转发语标题/落款加粗/删3Brain |
| 2026-08-16 | `24c713de` | **literature: 精读 Quintard 2024 -v3 Wiki.js 自带图床** (ID 1722, 6 张图永久) |
| 2026-08-16 | `290e9635` | **literature: 精读 Quintard 2024 -v2 修图床/双 H1/落款** (Wiki ID 1720) |
| 2026-08-16 | `0fc8db24` | **literature: 精读 Quintard 2024 Nat Commun - 微流控血管化类器官芯片** (Wiki ID 1719, NocoDB Id 3297) — **NEW external evidence** (10 通道并行微流控 + hiPSC-BVO 30 天功能性灌注培养 + 跨类器官验证) |
| 2026-08-12 | `297f106d` | **literature: 修齐 page 934 标杆** — H1 去括号 / 元数据用 bold / 📄PDF 文件名 (Liang 2026 v3) |
| 2026-08-12 | `aacba7aa` | **literature: frontmatter title 改中文 + 与正文 H1 一致** (Liang 2026 v2) |
| 2026-08-12 | `8699a154` | **literature: Liang 2026 Sci Rep liver organoid fibrosis - page 946 9 项 SOP 重写版** (Liang 2026 v2; 105+/122- lines; core-question / research-model / 6-finding 3-stage tables / 6 SeaFile Fig / "与我们的产品" 4-star / 4-paper refs / 转发语 / 完整落款) |
| 2026-08-12 | `e542c977` | **literature: Liang 2026 Sci Rep liver organoid + fibrosis platform (Id=770 NocoDB)** — **NEW external evidence** (3 轨道 Hep/Cho/HSC + DAPT+Dex P1-P10 长程成熟 + TGFβ 激活 HSC 体外纤维化模型; 7/7 Ollama qwen2.5vl 视觉审核通过; SeaFile 7/7 公网 200 验真; 飞轮 PATCH comm Id=87 + product Id=10 + NocoDB PATCH 770) |
| 2026-08-10 | `d97b39ed` | **Phase A 批量：6 篇精读加 Front Matter 6 字段** (doi/journal/year/volume/pages/authors/pmid) — Organoids 2026 review + CelVivo PAH + Shin 2024 + Fernandez Vallone 2026 + Liu 2026 + 类器官综述_CMOS_HD_MEA |
| 2026-08-10 | `3b929c2f` | **wang2024 方案 2 样品：6 个 Front Matter 字段 + 7 张图加 alt 描述** — `wang2024-org-on-chip.md` |
| 2026-08-10 | `6b717aef` | **MOC 方案 1 样品：建 1 个 MOC + 7 篇加 Front Matter (related: 反链)** — first MOC `MOC-类器官与3D培养.md` created; 7 papers got `related:` back-link frontmatter |
| 2026-08-09 | `a14758b1` | 精读: Wang 2024 Theranostics 类器官-芯片综述 (7 张配图 + Wiki.js ID 1700) — first Organoid-on-Chip 综述 / 7 大主题板块 |
| 2026-08-08 | `d7df3830` | cells paper v2: 双 H1 + 5张真图 (xref) — Fernandez Vallone 2026 |
| 2026-08-08 | `6c16dc05` | 精读: Fernandez Vallone 2026 Cells hiPSC 脑类器官 THSDC |
| 2026-08-07 | `65fef021` | fix: v2 with SeaFile links — Microbioreactor 2026 |
| 2026-08-07 | `18bee69f` | feat: Microbioreactor design 2026 Front Bioeng Biotechnol Mini Review (PMID 42516424) |
| 2026-08-08 | `1614ccf9` | fix: v11 - forwarding per skill template (Liu 2026) |
| 2026-08-08 | `a7cfb8a4` | fix: final - per Research SOP strict + clean internal traces (Liu 2026) |
| 2026-08-08 | `d1e8c6dd` | fix: v5 - per Research SOP + page 946 benchmark (Liu 2026) |
| 2026-08-08 | `b7882b81` | fix: v4 - add forward message (Liu 2026) |
| 2026-08-08 | `84e93402` | fix: v3 - Fig 3 restored from page 6, audit table removed (Liu 2026) |
| 2026-08-08 | `a69ad9c4` | literature: liu 2026 NBME shape-conformal organoid |
| 2026-08-08 | `1c05eee7` | literature: miao 2025 cell organoid vascularization v2 |
| 2026-08-08 | `a0810433` | 精读: Sharma K 2026 Cell Stem Cell 视网膜类器官血管化RGC存活与功能成熟 |
| 2026-07-29 | `2341383e` | fix(hook4): 湖北行去掉 'Robin 8 月出差高发地' 残留 (Robin 真实出差意图) |
| 2026-07-29 | `aa8fd2bc` | fix(hook4): 改标题 '下次出差' → '按 xlsx 缺口', Robin 后续自规划出差路径 |
| 2026-07-29 | `4b237a82` | feat(hook): 4 个经销商管理 Hook 升级 |
| 2026-07-29 | `b9da34dc` | fix(literature): Organoids 2026 综述 - 按 literature-deep-read-review SOP 重写 |
| 2026-07-29 | `0cd44fa0` | feat(literature): 精读 Organoids for disease modeling and treatment 2026 综述 |
| 2026-07-28 | `642e3dc6` | feat(agent): 新增代理商技术同事董慧群档案 (推 CelVivo 产品) |
| 2026-07-28 | `2718e46d` | feat(literature): Parate 2020 SCRT — PEMF 增强 MSC 旁分泌功能促软骨再生 |
| 2026-07-28 | `032de92f` | feat: 精读 Lee 2025 Front Vet Sci 犬脂肪源 MSC 3D 球体 |

The **2026-08-16 cluster** is a **two-paper LDR cycle on the same day**
covering both an **organ-on-chip microfluidic platform paper** and an
**organoid ethical-review systematic-review paper**:

- **Quintard C et al. (2024) Nat Commun DOI 10.1038/s41467-024-45710-4**
  — a microfluidic platform for vascularized organoids-on-chip. The
  paper establishes: (i) 10-channel parallel microfluidic chip (COC
  热压成型, U 型捕获位 300-800 µm 可调); (ii) fibrin + Matrigel hydrogel
  with Landau-Levich-Bretherton 效应 → 100% 捕获效率 in 10 sec per
  channel; (iii) hiPSC-derived blood vessel organoids (BVO, day 15)
  + GFP-HUVEC + 纤维细胞共培养 → 30 天功能性灌注培养; (iv) 壁剪切速率
  27-2000 s⁻¹, mean 134-531 s⁻¹ (与人体毛细血管生理范围 50-1900 s⁻¹
  完美匹配); (v) 层级化血管: 37 µm 上游动脉-静脉 + 8 µm BVO 毛细管.
  The 4 commits are the same single file
  `obsidian-vault/Literature/Deep-Reads/Organoid/quintard_2024_vasorganoid_chip.md`
  walked through Robin's standard LDR cycle: (a) **`0fc8db24`** adds
  the file (189 lines, single-pass entry); (b) **`290e9635`** rewrites
  to -v2 修图床/双 H1/落款; (c) **`24c713de`** adds -v3 Wiki.js 自带
  图床 6 张图 (永久); (d) **`4073abf4`** is the -v4 转发语标题/落款
  加粗 + 删 3Brain 工具名硬门槛合规修正. The "与我们的产品" table on
  the paper lists **Mimetas OrganoPlate ⭐⭐⭐⭐ (直接对标: Phaseguide
  微流控技术)** + **CelVivo ClinoStar ⭐⭐⭐ (类器官前段成熟期培养:
  BVO 在 hiPSC 分化到 day 15 需要悬浮旋转培养, ClinoStar 是该步骤
  的金标准; day 15 后才转入芯片, ClinoStar 是完整工作流的前置)** +
  **Emulate Organ-Chip ⭐⭐⭐**.
- **Guo Z, Zhang N (2026) Front Cell Dev Biol DOI 10.3389/fcell.2026.1721946**
  — an IRB / ethical-review systematic-review paper for organoid
  biomedical research. The paper establishes: (i) **7 大强制要点**
  (样本来源合法性 / 捐赠者知情同意 [unlimited expansion / long-term
  cryopreservation / inter-lab sharing / cross-border / future
  unspecified research / commercial use / withdrawal mechanism] /
  数据隐私与去标识化 / 共培养产物主体性评估 [Guo 2026 首次提出] /
  动物福利 3R 原则 / 跨境监管合规 [中国 / 美国 / 欧盟 / 日本 / 韩国
  对照表] / 长期保存与终止使用); (ii) **中国 IRB 实务视角 + 国际
  ISSCR / GDPR / OHRP 双重参照** (作者团队 = 嘉兴市第一医院医学伦理
  委员会 + 嘉兴大学医学院, 中国 IRB 实践者); (iii) **共培养产物
  "新伦理实体" 框架** = 类器官 + 免疫细胞共培养 (CAR-T 培养) 不构成
  "新生物体" 但构成 "新伦理实体", 需要独立审查. The 3 commits are
  the same single file
  `obsidian-vault/Literature/Deep-Reads/Organoid/guo_2026_organoid_ethical_review.md`
  walked through Robin's standard LDR cycle: (a) **`2e6f5989`** adds
  the file (170 lines, single-pass entry); (b) **`00f824f2`** -v2 修
  图床 (加 2 张 Wiki.js 自带图); (c) **`a4fa5a32`** -v3 补 Fig 1
  (3 张图全) — Fig 1 is the "类器官共培养模型" 概念图 (Robin 8-16
  实战反思: 综述类概念图通常较小, 提取阈值要从 0KB 起步全收, 再按
  caption 关联; 之前 >200KB 过滤漏了 Fig 1). The "与我们的产品"
  table on the paper lists **CelVivo ClinoStar ⭐⭐⭐⭐ (临床转化类
  器官的伦理合规——本文 7 大要点直接适用于 ClinoStar 客户 IRB 申请;
  Robin 推广 ClinoStar 给三甲医院时, 可附带本框架作为增值)** +
  **Mimetas OrganoPlate ⭐⭐⭐⭐ (类器官共培养芯片的伦理审查依据——
  Mimetas 主打"类器官 + 免疫细胞共培养", 本文主题 B 的共培养伦理
  框架直接适用)** + **Emulate Organ-Chip ⭐⭐⭐ (类器官 + 微流控
  芯片的跨境监管参考)**.

The **2026-08-12 cluster** is a **single-paper LDR cycle** on
**Liang Y et al. (2026) Sci Rep DOI 10.1038/s41598-026-42990-2** — a
mouse liver organoid platform paper from 澳门科技大学 + 香港大学 that
establishes: (i) single-tissue 3-轨道 (Hep-Orgs + Cho-Orgs + HSC)
separation; (ii) DAPT (Notch 抑制) + Dexamethasone for P1-P10 长程
稳定成熟 (ALB / PAS / LDL / CYP all stable across 10 passages — single
DAPT only sustains P5); (iii) TGFβ 5-7 day activation of qHSC → aHSC
(Acta2 / Col1a1 上调); (iv) aHSC 共培养诱导 Hep-Orgs EMT
(Snail / Twist / Vimentin ↑; ALB / CK8 ↓; Lgr5 / EpCAM ↓; Ki67 ↓) =
体外肝纤维化模型. The 4 commits are the **same single file**
`04-Literature/Deep-Reads/Liver/2026-08-12_Liang_2026_SciRep_liver_organoid_fibrosis_platform.md`
walked through Robin's standard 3-stage SOP cycle: (a) **`e542c977`**
adds the file (186 lines, single-pass entry); (b) **`8699a154`** rewrites
the same file to the page 946 9 项 SOP 标杆 (105+/122- lines, adding
the 6 核心发现 三段式 tables + 6 SeaFile Fig + "与我们的产品" 4-star
table + 4-paper 参考文献 + 转发语 + 完整落款 + SeaFile PDF link); (c)
**`aacba7aa`** + **`297f106d`** are the **page 934 修齐** micro-revisions
(frontmatter title 改中文 / H1 去括号 / 元数据用 bold 单行 / 📄PDF
文件名 with actual filename) — the same alignment Robin applied across
the 2026-08-11 OVB-类器官 cycle. The "与我们的产品" 4-star table
on the paper lists CelVivo ClinoStar ⭐⭐⭐⭐ (P1-P10 长程扩增对应
旋转培养 30+ 天无剪切; HSC 静止态在模拟微重力下 7+ 天维持) +
CelVivo ClinoReactor ⭐⭐⭐⭐ (单组织 3 轨道分通道灌流; TGFβ 时间程序
精确切换) + CelVivo PhaseHolographic 成像 ⭐⭐⭐ + 3Brain HD-MEA ⭐⭐⭐
(肝-神经互作延伸).

**No new vault commits landed in the 2026-08-12T18:08Z →
2026-08-13T18:08Z window** — the vault HEAD is unchanged at
`297f106d`. The 2026-08-12 Liang 2026 cluster remains the most recent
committed vault activity. One new uncommitted file appeared in the
working tree this fetch:
`04-Literature/Deep-Reads/Review/zhou2023_computer_vision_microfluidics.md`
— the **first entry in a new `Review/` subfolder** (see the
Notable-entity section below).

**7 new vault commits landed in the 2026-08-15T18:07Z →
2026-08-17T18:09Z window** — the vault HEAD bumped from `297f106d`
to `a4fa5a32`. The two 2026-08-16 LDR cycles (Quintard 2024
microfluidic organ-on-chip + Guo 2026 organoid ethics systematic
review) are the **first time since the 2026-07-28 / 2026-07-29
Parate / Lee / Hodge cluster** that two new paper deep-reads landed
on `main` in the same 48-hour window. The 2026-08-16 cluster
replaces the 2026-08-12 Liang 2026 cluster as the most recent
committed vault activity. Two new untracked directories appeared in
the working tree this fetch: `celvivo_commercial/1331651_20260630_131201.pdf`
(the 6-30 quote PDF migrated into a new folder) + `templates/类器官IRB申请清单.md`
(the IRB application checklist derived from Guo 2026 — Robin's first
customer-facing sales ammunition template produced from a single
deep-read; see the Notable-entity section below for synthesis).

The **2026-08-10 cluster** is a **frontmatter-hygiene + MOC-discipline
sprint** rather than new external evidence: (a) **Phase A batch**
(`d97b39ed`) standardized 6 deep-read notes with the structured 6-field
frontmatter (doi / journal / year / **volume** / **pages** /
**authors** array / pmid) that the prior notes had been missing; (b)
**方案 2 样品** (`3b929c2f`) added 7 image alt descriptions on top of the
6-field frontmatter for `wang2024-org-on-chip.md`; (c) **MOC 方案 1
样品** (`6b717aef`) created Robin's first Map-of-Content file
(`04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md`, 95 lines, 沙牛《AI
时代的 Obsidian 公开课》课时 1 pattern) and added `related:` back-link
frontmatter to 7 papers. The MOC's own `related:` list already names
the next planned MOC — `[[MOC-3Brain-HD-MEA]]` — plus
`[[02-Clients/Agents/_known_associations]]` and
`[[02-Active-Deals/CellShot-TriArm-Demo-计划-v2-老师版-2026-07-20]]`,
so the MOC pattern is expected to extend.

The **2026-08-08 cluster** (prior manifest) was the literature
flywheel-sync output (Liu 2026, Miao 2025 v2, Sharma 2026) — already
indexed on [`/sources/literature.md`](/sources/literature.md). The
**2026-08-07 / 2026-08-08 micro-revisions** on Liu 2026 (`a69ad9c4` →
`1614ccf9`) are the 8-step SOP rewrite cycle (v3 → v11) Robin re-ran
on the same paper.

## openwiki-wiki — working-tree status (2026-08-17)

- **Branch:** `main`
- **HEAD:** `be4928553364a654b888807a44438b738072c2ce` (the
  `chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts
  (sources-sync 2026-08-17)` commit — same auto-source-sync job that
  carried the 2026-08-15 count-data wipe; see Notable-entity §
  "2026-08-15 sources-sync bug" for the operational note).
- **Working-tree state:** 9 modified files (uncommitted — pending next
  CLI orchestration), **down from 10 at the 2026-08-15 fetch**
  (the `sources/index.md` from the 2026-08-15 dirty set was committed
  in the 2026-08-16 daily update `151d22b`). The 9 dirty files are:
  - `.last-update.json` — CLI metadata, will be updated when this run's
    `status: complete` lands.
  - `quickstart.md` — contains the accumulated "Latest update"
    paragraphs from the prior HN-1 2026-08-15 + web-search-1 2026-08-15
    + git-repo-1 2026-08-13 runs, plus the new "Latest update —
    git-repo-1 (2026-08-15T18:07Z)" paragraph this run is adding.
  - `sources/README.md` — refreshed connector-roll table row for
    web-search-1 (added the 2026-08-15 skip to the 4-entry skip streak)
    + added frontmatter placeholders to nocodb.md / ragflow.md /
    seafile.md / wikijs.md during the 2026-08-15 daily update.
  - `sources/hackernews.md` — accumulated "Latest update —
    2026-08-15 18:00 UTC" + "Latest update — 2026-08-16 18:00 UTC" +
    "Latest update — 2026-08-17 18:00 UTC" sections from the prior
    HN-1 2026-08-15 + HN-1 2026-08-16 + HN-1 2026-08-17 runs
    (Auto-research with codex 232x Faster Kernel + Anthropic multi-agent
    + Stripe/OpenRouter + Copilot Autofix + Qwen 3.8 27B + Agent Mesh
    flag-for-traceability callouts + the 4th / 5th / 6th consecutive
    empty / noise-only Algolia lane streak notes) — landed in
    uncommitted state during the HN-1 runs.
  - `sources/nocodb.md` — `openwiki_generated: true` placeholder
    frontmatter auto-applied during the 2026-08-15 daily update +
    carried forward in 2026-08-16 + 2026-08-17 daily updates; **count
    data wiped** by `2507925` 2026-08-15 sources-sync (NocoDB went
    from 6614 → 0 records).
  - `sources/ragflow.md` — same `openwiki_generated: true` placeholder
    auto-applied during the 2026-08-15 daily update; **count data
    wiped** by `2507925` 2026-08-15 sources-sync (landing went from
    200 → 000).
  - `sources/seafile.md` — same `openwiki_generated: true` placeholder
    auto-applied during the 2026-08-15 daily update; **count data
    wiped** by `2507925` 2026-08-15 sources-sync (libraries table
    emptied — SeaFile was already empty in `1737454` already — a
    separate, older cron issue not introduced by `2507925`).
  - `sources/web-search.md` — accumulated "2026-08-15 attempted
    update — skipped" + "2026-08-17 attempted update — skipped"
    sections from the web-search-1 2026-08-15 + 2026-08-17 runs
    (5th + 6th consecutive skips on the same code path).
  - `sources/wikijs.md` — same `openwiki_generated: true` placeholder
    auto-applied during the 2026-08-15 daily update; **count data
    wiped** by `2507925` 2026-08-15 sources-sync (Wiki.js went from
    83 → 0 unique pages; ID range 22..1704 → 0..0).
- **Auth:** local path only — no remote, no credentials.
- **New file in this window:** `sources/openwiki-version-drift.md`
  was created in the 2026-08-17 daily update commit `5c70881` (auto-
  generated page that tracks OpenWiki installed-vs-npm-latest version
  drift; reports v0.3.1 local → v0.3.3 npm latest as of
  2026-08-15T20:00:03Z; the page sits on the wiki to surface the
  drift without an external daemon).
- **Auth:** local path only — no remote, no credentials.

### Recent commits (latest first)

| Date | Hash | Note |
| --- | --- | --- |
| 2026-08-17 | `be49285` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-17) |
| 2026-08-17 | `5c70881` | chore: daily update 2026-08-17 (added `sources/openwiki-version-drift.md` auto-generated page + refreshed HN-1 / web-search-1 / git-repo-1 sections) |
| 2026-08-16 | `997b648` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-16) |
| 2026-08-16 | `151d22b` | chore: daily update 2026-08-16 (committed `sources/index.md` from the 2026-08-15 dirty set; refreshed HN-1 / web-search-1 / git-repo-1 / themes/05-robin-research sections) |
| 2026-08-15 | `2507925` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-15) — **count-data wipe** (NocoDB 6614 → 0, Wiki.js 83 → 0, RAGFlow landing 200 → 000); see Notable-entity § "2026-08-15 sources-sync bug" |
| 2026-08-15 | `173b58c` | chore: daily update 2026-08-15 (added OKF frontmatter to nocodb.md / ragflow.md / seafile.md / wikijs.md) |
| 2026-08-14 | `6258717` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-14) |
| 2026-08-14 | `021e929` | chore: daily update 2026-08-14 |
| 2026-08-13 | `1737454` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-13) |
| 2026-08-13 | `8ddc6d9` | chore: daily update 2026-08-13 (commitment + quickstart + sources/literature + sources/web-search + themes/01-organoid-equipment + themes/05-robin-research from the HN-1 2026-08-13 synthesis pass) |
| 2026-08-12 | `c57ead4` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-12) |
| 2026-08-12 | `431ee6a` | chore: daily update 2026-08-12 |
| 2026-08-11 | `b64ae41` | lit: PMID 41536916 Bioactive Materials AIVOs 综述 (Wiki.js 1711) |
| 2026-08-11 | `523ee7f` | lit: PMID 41686639 Cell Reports TNBC DEO + ROCK (Wiki.js 1710) |
| 2026-08-11 | `9be4f55` | lit: PMID 41909700 Front Immunol 2026 类器官-小胶质细胞综述 (Wiki.js 1709) |
| 2026-08-11 | `cc69ece` | lit: PMID 42041571 v4 - 按 literature-deep-read-research 9 项强制格式 |
| 2026-08-11 | `b4bc8d9` | lit: PMID 42041571 修正 - 真实PDF + 10张真图链接 |
| 2026-08-11 | `12480ab` | lit: 修正 wiki_url 到真实内网地址 |
| 2026-08-11 | `cdc59c5` | lit: PMID 42041571 OVB-organoids vs cerebral organoids Cells 2026 |
| 2026-08-11 | `2bcde39` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-11) |
| 2026-08-11 | `7556e31` | chore: daily update 2026-08-11 |
| 2026-08-09 | `dde053a` | auto: 2026-08-09 Wang 2024 Theranostics OrgOC 综述精读入口 |
| 2026-08-09 | `3267338` | chore: daily update 2026-08-09 |
| 2026-08-09 | `06f60e1` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-09) |
| 2026-08-08 | `c94940c7` | feat: add Microbioreactor 2026 v4 (PMID 42516424, ID 1696) |
| 2026-08-08 | `7f65024` | feat: add Microbioreactor 2026 v3 (PMID 42516424) |
| 2026-08-08 | `ea4f14a` | feat: add Microbioreactor 2026 v2 (PMID 42516424) |
| 2026-08-08 | `a193e46` | feat: add Microbioreactor 2026 (PMID 42516424) deep-read entry |
| 2026-08-08 | `bf90a91` | fix: liu 2026 wiki link to main path |
| 2026-08-08 | `cf1dbe0` | fix: liu 2026 final link |
| 2026-08-08 | `26efd2f` | fix: liu 2026 v5 link |
| 2026-08-08 | `e18993a` | fix: liu 2026 v4 link |
| 2026-08-08 | `b206bd9` | fix: liu 2026 v3 link |
| 2026-08-08 | `c26dbdf` | fix: liu 2026 wiki link to v2 |
| 2026-08-08 | `703c3d4` | literature: liu 2026 NBME shape-conformal organoid |
| 2026-08-08 | `1b78735` | literature: miao 2025 cell v2 |
| 2026-08-08 | `5adc406` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-08) |
| 2026-08-08 | `037c5f3` | lit: add Sharma K 2026 Cell Stem Cell vRO retinal organoid (PMID 41529691) |
| 2026-08-07 | `9e80977` | feat(openwiki): complete data flywheel activation (2026-08-07) |
| 2026-08-07 | `45af5a4` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-07) |
| 2026-08-07 | `bcd4a4f` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-07) |
| 2026-08-07 | `0bbef0f` | feat(openwiki v0.3.1 --update): generate themes 4-5 + index.md + themes/ + sources/ index (2026-08-07) |
| 2026-08-07 | `285c53b` | feat(openwiki v0.3.1): add YAML frontmatter + install-id markers from initial init run (2026-08-07) |
| 2026-07-24 | `3102e96` | feat(sources): 全国 261 家经销商地图 (2026-07-24, 不含敏感信息) |

The wiki repo is the OpenWiki output itself — it persists across
update runs. **4 new wiki-side commits landed in the
2026-08-13T18:08Z → 2026-08-15T18:07Z window**: (a) `021e929`
(2026-08-14 +0800 02:18, `chore: daily update 2026-08-14`); (b)
`6258717` (2026-08-14 +0800 02:30, `chore(sources): refresh
NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-14)`);
(c) `173b58c` (2026-08-15 +0800 02:00, `chore: daily update 2026-08-15`
— added OKF frontmatter to nocodb.md / ragflow.md / seafile.md /
wikijs.md); (d) `2507925` (2026-08-15 +0800 02:31, `chore(sources):
refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync
2026-08-15)` — **count-data wipe** carried into the source pages; see
Notable-entity § "2026-08-15 sources-sync bug" below). Between these 4
commits, the wiki HEAD advanced from `1737454` (2026-08-13
sources-sync) to `2507925` (2026-08-15 sources-sync). The 6 wiki commits
from 2026-08-11 / 2026-08-12 (`7556e31` / `431ee6a` daily +
`2bcde39` / `c57ead4` sources-sync + the 6 lit-PMID commits on
2026-08-11 + `2bc03f3` / `06f60e1` / `5adc406` / `3267338` /
`dde053a` from the 2026-08-08 / 2026-08-09 cluster) are all already in
`2507925`'s ancestry. The **Liang 2026 wiki sync** has not yet landed
(the `/sources/literature.md` short row is in working tree only); the
next wiki commit should add a fuller Liang 2026 row when the synthesis
pipeline catches up.

### Summary of last 48 hours

| Window (UTC) | Vault | Wiki |
| --- | --- | --- |
| 2026-08-15T18:07:49Z → 2026-08-17T18:09:32Z | HEAD `297f106d` → `a4fa5a32` (**7 new commits**: `0fc8db24` + `290e9635` + `24c713de` + `4073abf4` Quintard 2024 Nat Commun microfluidic vascularized organoid chip 4-commit LDR cycle + `2e6f5989` + `00f824f2` + `a4fa5a32` Guo 2026 Front Cell Dev Biol organoid ethics systematic review 3-commit LDR cycle — **first time since the 2026-07-28 / 2026-07-29 Parate / Lee / Hodge cluster that two new paper deep-reads landed on `main` in the same 48-hour window**) | HEAD `2507925` → `be49285` (**4 new commits**: `151d22b` daily update 2026-08-16 + `997b648` sources-sync 2026-08-16 + `5c70881` daily update 2026-08-17 + `be49285` sources-sync 2026-08-17) |
| **Net new external evidence** | **2 new paper deep-reads**: Quintard 2024 Nat Commun microfluidic vascularized organoid chip + Guo 2026 Front Cell Dev Biol organoid ethics systematic review. **2 new untracked directories**: `celvivo_commercial/1331651_20260630_131201.pdf` (the 6-30 quote PDF migrated into a new folder) + `templates/类器官IRB申请清单.md` (the IRB application checklist derived from Guo 2026 — Robin's first customer-facing sales ammunition template produced from a single deep-read). The `Review/zhou2023_computer_vision_microfluidics.md` first-entry-in-Review/-subfolder is still untracked, carrying forward from the 2026-08-13 fetch | **1 new wiki file**: `sources/openwiki-version-drift.md` (auto-generated OpenWiki version-drift monitor; v0.3.1 local → v0.3.3 npm latest as of 2026-08-15T20:00:03Z). Synthesis-layer edits accumulated across the prior HN-1 2026-08-13 + HN-1 2026-08-15 + HN-1 2026-08-16 + HN-1 2026-08-17 + web-search-1 2026-08-15 + web-search-1 2026-08-17 + git-repo-1 2026-08-13 + git-repo-1 2026-08-15 runs are pending the next CLI commit cycle |
| Untracked → committed migrations | **Quintard 2024 file (4 commits)** + **Guo 2026 file (3 commits)** all moved from absent → committed on `main`; **the 2 new untracked directories** are net-new in this window | **none** of the 9 dirty files were committed in this window (the `sources/index.md` from the 2026-08-15 dirty set was committed by the 2026-08-16 daily update `151d22b`; the remaining 9 dirty files are uncommitted synthesis edits accumulated across the prior HN-1 + web-search-1 + git-repo-1 runs); the 9 dirty files (`.last-update.json` + `quickstart.md` + `sources/{README,hackernews,nocodb,ragflow,seafile,web-search,wikijs}.md`) are awaiting the next CLI commit cycle |
| **Operational issue carried over from prior runs** | n/a | **`2507925` 2026-08-15 sources-sync bug** + the 2026-08-16 `997b648` + 2026-08-17 `be49285` sources-syncs (which re-applied the same operational pattern as `2507925` — NocoDB / Wiki.js / RAGFlow count values stayed zero across all 3 sources-syncs). The on-disk `~/.openwiki/connectors/web-search/config.json` is unaffected — this is a wiki-side CRON issue with the auto-source-sync job, not a connector config issue. Recorded for traceability on `/sources/git-repo.md` Notable-entity § "2026-08-15 sources-sync bug" and on each affected `/sources/{nocodb,ragflow,seafile,wikijs}.md` page. The data is recoverable from `git show 8ddc6d9:sources/nocodb.md` etc. for any future recovery commit |

## Vault navigation index

The vault uses a numbered top-level layout. Scripts, caches, and `temp*`
working folders are excluded from this index.

| Dir | Purpose | Size hint |
| --- | --- | --- |
| `01-Active-Sales/` | Active sales pipeline files (board + per-account) | 6 .md |
| `02-Active-Deals/` | Deal-level active docs | 1 .md |
| `02-Clients/`, `02-Contacts/` | Client & contact records | sparse |
| `03-Product/` | Product briefs (e.g. 3Brain-Maxwell comparison) | 1 .md |
| `03-Resources/Agents/` | Distributor / agent profiles | a handful |
| `03-Resources/End-Customers/` | End-customer dossiers (3Brain MEA accounts, etc.) | 11+ .md |
| `03-Resources/ITX-24h-Host/` | Personal 24h Hermes-Agent / AI-workflow host build config (2026-07-31 untracked; not yet on `main`) | 1 .md |
| `04-Literature/` | Paper deep-reads + curated vendor PDFs | see breakdown |
| `05-Documents/Contracts/` | Signed/pending contracts (Celvivo subfolder) | — |
| `05-Documents/Products/` | Vendor-facing product docs (Celvivo/Industrial-Customers) | — |
| `05-Documents/{Proposals,Quotes,Visit-Plans}/` | Active commercial docs | — |
| `05-Products/` | In-house product briefs (MappingLab family) | 2 .md |
| `06-Sales/Competitors/` | Competitor tracking | — |
| `06-Sales/Configurations/` | Product configurations | — |
| `06-Sales/Content/{FAQ,Pain-Points,PPT-Scripts,Success-Stories,Training-Materials,推文模板}/` | Sales content library | — |
| `06-Sales/{Price-List,Product-Mapping,Recommendation-Engine}/` | Sales tooling | — |
| `99-Templates/` | Reusable Obsidian templates | 14 .md |
| `memory/` | Daily reports, weekly digests, `.dreams`, archive | 147 .md |

### `04-Literature/Deep-Reads/` breakdown

Markdown file counts per deep-read subfolder:

| Subfolder | .md count |
| --- | --- |
| `Organoid/` | 661 (+2 from 2026-08-16 — Quintard 2024 Nat Commun microfluidic vascularized organoid chip + Guo 2026 Front Cell Dev Biol organoid ethics systematic review) |
| `Celvivo/` | 142 |
| `3Brain/` | 136 |
| `Cellink/` | 129 |
| `Organoid-List/` | 51 |
| `Product-Reports/` | 38 |
| `Brain/` | 11 |
| `Brain-Tumor/` | 9 |
| `Cancer/` | 6 |
| `Liver/` | 6 |
| `Other/` | 6 |
| `RegenMed/` | 1 |
| `3Brain MEA/` | 3 |
| `Cardiac/` | 2 |
| `Kidney/` | 2 |
| `Retinal/` | 1 |
| `Microbioreactor/` | 1 (new as of 2026-08-07 — Rosero 2026 Front Bioeng Biotechnol) |
| `Cells/` | 1 (new as of 2026-08-08 — Fernandez Vallone 2026 Cells THSDC) |
| `Review/` | 1 (new as of 2026-08-13 — Zhou 2023 computer vision + microfluidics, **untracked**) |
| `templates/` | 1 (new as of 2026-08-17 — `类器官IRB申请清单.md`, derived from the Guo 2026 ethics deep-read; Robin's first customer-facing template produced from a single deep-read, **untracked**) |
| `celvivo_commercial/` | 1 (new as of 2026-08-17 — `1331651_20260630_131201.pdf`, the 6-30 quote PDF migrated into a new folder, **untracked**) |

Total ≈ 1,207 deep-read notes on `main` (+2 from the 2026-08-16 Quintard 2024 + Guo 2026 clusters).
Review/ zhou2023 computer vision + microfluidics, **untracked** — only
counts once committed; +2 working-tree files in the new `templates/` +
`celvivo_commercial/` directories, both untracked). The 2026-08-16 Quintard 2024 + Guo 2026 cluster is the most recent committed deep-read additions; the 2026-08-07 / 2026-08-08 cluster (Microbioreactor + Cells) remains the prior committed cluster. CelVivo, 3Brain, Cellink, and the broad `Organoid/` bucket cover Robin's product KB per the wiki goal focus areas (类器官培养与设备, 3D 生物打印). The new `templates/` folder signals Robin may be formalizing customer-facing deliverables (checklists / templates / sales scripts) as a separate vault subtree — the IRB application checklist is the first such artifact.

## Distributor map refresh (2026-08-07)

Robin uploaded a refreshed `b7f52af896c1e3a9.xlsx` on 2026-08-07 11:11,
producing **8 new `*2026-0807.md` regional files** + a new
`全国经销商地图-2026-0807.md` index + a new **product-association
index** (`_known_associations.md`) + a new `_meta.json` reflecting the
259-dealer tally. The 2026-07-24 baseline (`*2026-0724.md` × 7 + index)
remains in the repo but is now stale.

What changed in the 2026-08-07 baseline vs the 2026-07-24 baseline:

| Dimension | 2026-07-24 (`_meta.json`) | 2026-08-07 (`全国经销商地图-2026-0807.md`) |
| --- | --- | --- |
| Total dealers | 261 (明细表口径) | 259 (公司数量汇总) |
| xlsx sha256 | `3afd448edcf3a9673848da0de2c554e6a4b22d7329b988695ca242c8bc8c10cf` | (re-uploaded with 8-04 同名 + 新增 2-3 家) |
| Region table | 华北 74 / 华东 68 / 华南 62 / 山东 25 / 湖北 19 / 西北 6 / 西南 7 | 华北 72 / 华东 68 / 华南 62 / 山东 25 / 湖北 19 / 西北 6 / 西南 7 |
| 华北 count | 74 | 72 (-2) |
| Hook 4 output | (none) | 4 dealer-management hooks + `_known_associations.md` |

The numeric 261 vs 259 difference is still rooted in the **华北 表 74 vs
汇总 72** discrepancy (two unnamed companies — 序号 63 / 67 — leave the
明细表 2 rows above the 汇总表); the 2026-08-07 baseline carries the
same data anomaly plus a new structural artifact: **济南成全生物科技
(曹沛起) is registered in both `华北-2026-0807.md` and `山东-2026-0807.md`
(legitimate cross-region duplicate)** — this is the only CelVivo
ClinoStar agent in the 259-dealer list and is the thread Robin should
follow to close the `agent-dong-huiqun-celvivo` open question.

### `_known_associations.md` (2026-08-07) — product → dealer mapping

The new index file `02-Clients/Agents/_known_associations.md` is the
canonical hook-4 output Robin needs to evaluate before the next
Chinese-region dealer visit. Key mappings surfaced (5 direct hits):

| Product line | 261-dealer表 命中 | 关联客户 / 商机 |
| --- | --- | --- |
| **CelVivo (ClinoStar / ClinoReactor)** | **济南成全生物科技有限公司 (曹沛起)** — registered in both 华北 + 山东 (cross-region, 2 次) | 董慧群关联 (待 Robin 确认是否同公司) |
| **FemtoBiomed (CellShot / PROLIVA)** | 0 direct hits (9X Bio / 汇佰生物 is the direct intermediate, not in the 261 dealer list) | TriArm Therapeutics (翁靖傑, 上海 CGT/CAR-T) — 128 万 Phase1 / 8-10 至 8-14 现场 demo |
| **3Brain (HD-MEA)** | 0 direct hits | — |
| **Cellink (BIO X)** | 0 direct hits | — |
| **西南医大 心研所 殴贤红** | 2 dealers: 成都百乐 (杨军, 钻石级 1亿, Bio-Rad / Sartorius / Oxford Nanopore / Cytek / Leica, 覆盖川渝黔藏) + 成都立德赛 (川渝云贵陕) | (待 Robin 决策) |

**Hook-4 questions** (Robin 优先补全, per `_known_associations.md`):

1. 董慧群 is which specific technical contact at 济南成全 — or is she at a
   different CelVivo-代理?
2. 西南医大 殴贤红 → 成都百乐 vs 成都立德赛 — which dealer first?
3. 邓昊伦 (02-Contacts/) 蛇类神经方向 → 3Brain HD-MEA 拜访?
4. 261 dealer 表 has 0 3Brain / Cellink 代理 — is the dealer list
   incomplete, or does Robin need to actively recruit those dealers?

Log these as a new commitment on `/commitments.md`
(`distributor-8-07-association-followup`) and as updates to
`/open-questions.md` (the `agent-dong-huiqun-celvivo` question now
**partially answered** — agency identified but personal contact
fields still 待补).

## Notable entities surfaced by the vault (structural hints only)

- **Quintard 2024 Nat Commun microfluidic vascularized organoid chip (2026-08-16, 7 commits in 48-hour window)** — `obsidian-vault/Literature/Deep-Reads/Organoid/quintard_2024_vasorganoid_chip.md` (189 lines; 4-commit LDR cycle `0fc8db24` adds → `290e9635` -v2 修图床/双 H1/落款 → `24c713de` -v3 Wiki.js 自带图床 6 张图 → `4073abf4` -v4 转发语标题/落款加粗/删 3Brain; Wiki IDs 1719/1720/1722, NocoDB Id 3297). The paper is **the first microfluidic / organ-on-chip platform paper** Robin has deep-read in the 2026-08 window; the platform combines (i) 10-channel parallel microfluidic chips with U-shaped capture sites (300-800 µm adjustable), (ii) fibrin + Matrigel hydrogel layer deposition using Landau-Levich-Bretherton effect, (iii) ~10 s capture efficiency ~100%, (iv) dynamic perfusion 7-30 days with HUVEC + fibroblast co-culture + hiPSC-derived BVO + islet spheroid + lung organoid cross-validation, (v) hierarchical vasculature (37 µm upstream artery-vein + 8 µm BVO capillaries, matching physiological ranges 50-1900 s⁻¹). **Net-new external evidence** in this run (git-repo-1 2026-08-17). The 4-star "与我们的产品" table lists **Mimetas OrganoPlate ⭐⭐⭐⭐** (direct Phaseguide-based vascularized / kidney / intestine organ-on-chip competitor) + **CelVivo ClinoStar ⭐⭐⭐** (upstream workflow step: BVO differentiation day 0-15 needs rotating-wall suspension culture; ClinoStar is the canonical hardware for this stage; the paper's day 15 → chip-on-board handoff is the canonical CelVivo → organ-on-chip workflow) + **Emulate Organ-Chip ⭐⭐⭐** (Colon-Intestine-Liver platform companion). Synthesis routes into `/themes/05-robin-research.md` (新增 by-vendor entry) and `/sources/literature.md` (last-30-days deep-read table). Vendor-anchor mapping: CelVivo-adjacent (workflow upstream) + Mimetas OrganoPlate / Emulate Organ-Chip (organ-on-chip product lane that Robin's portfolio does not currently cover but represents a potential cross-sell if Robin's customers ask "where do I run my CelVivo-matured organoids in a vascularized microenvironment?"). Customer-entry: 药企临床前 (vascularized drug screening) + 微流控 organ-on-chip 平台集成商 (Mimetas / Emulate channel partners) + academic PI (vascular development / diabetes). **Track on next fetch** whether Robin publishes a `/sources/literature-quintard-2024-nat-commun-vasorganoid-chip-deepread.md` synthesis page; the deep-read pipeline currently only carries `liang-2026-celvivo-clinostar-positioning` + `miao-2025-celvivo-clinostar-positioning` + `liu-2026-hd-mea-roadmap-implication` + `sharma-2026-retinal-organoid-mea-cross-sell` — no Quintard synthesis page yet.
- **Guo 2026 Front Cell Dev Biol organoid ethics systematic review (2026-08-16, 7 commits in 48-hour window)** — `obsidian-vault/Literature/Deep-Reads/Organoid/guo_2026_organoid_ethical_review.md` (170 lines + 3 真图; 3-commit LDR cycle `2e6f5989` adds → `00f824f2` -v2 修图床 (加 2 张 Wiki.js 自带图) → `a4fa5a32` -v3 补 Fig 1; Wiki ID 1724, NocoDB Id 3298). The paper is **the first organoid-research ethics / IRB systematic review** Robin has deep-read in any window — fills the methodological gap on the IRB-side that the prior clinical-translation evidence (CDE classification + Order No. 818) does not directly cover. The paper structures the IRB review framework as **7 mandatory points** (sample provenance + donor informed consent + data privacy & de-identification + co-culture agency + animal welfare 3R + cross-border regulation + long-term storage & termination); the cross-border table compares China (《人类遗传资源管理条例》+ 《涉及人的生命科学和医学研究伦理审查办法》2023), US (HIPAA + Common Rule + NIH GDS), EU (GDPR + Clinical Trials Regulation 536/2014), Japan, Korea. The 4-star "与我们的产品" table lists **CelVivo ClinoStar ⭐⭐⭐⭐** (clinical-translation IRB compliance — the 7 mandatory points directly apply to ClinoStar customer IRB submissions; **Robin 推广 ClinoStar 给三甲医院时, 可附带本框架作为增值**) + **Mimetas OrganoPlate ⭐⭐⭐⭐** (co-culture ethics — Mimetas 主营类器官 + 免疫细胞共培养, the co-culture agency framework from Guo 2026 point 4 directly applies) + **Emulate Organ-Chip ⭐⭐⭐** (organoid + microfluidic cross-border regulation reference). **Net-new external evidence** in this run (git-repo-1 2026-08-17). Robin translated the paper into a **customer-facing sales ammunition template** at `templates/类器官IRB申请清单.md` (180 lines; 7 mandatory points checklist + 5 customer Q&A + China vs International flow table + 10 attachments + 7 citations; v1.0 dated 2026-08-16, "Robin 8-16 实战沉淀") — see the templates/ entry in the next bullet. Customer-entry: 临床转化型医院 (class A tertiary hospitals running organoid IRB submissions) + 类器官厂家 Robin 培训客户 (the IRB checklist is the canonical "Robin 培训客户 IRB 申请" core material) + academic PI (cross-border collaboration IRB paperwork). **Track on next fetch** whether (a) the templates/ IRB checklist gets committed, (b) the Robin-author attribution in the template is recognized as a wiki-side customer-training artifact, (c) Robin produces a deep-read synthesis page at `/sources/literature-guo-2026-front-cell-dev-biol-organoid-ethics-deepread.md`, and (d) the IRB checklist routes into the existing CelVivo industrial-customers program (which currently lives at `05-Documents/Products/Celvivo/Industrial-Customers/`) as a standard customer-training artifact.
- **Review/ subfolder — first entry (2026-08-13, still uncommitted at 2026-08-17, 4-day carry-forward, watchlist signal weakening)** — `obsidian-vault/04-Literature/Deep-Reads/Review/zhou2023_computer_vision_microfluidics.md` is the **first file in a new `Review/` subfolder** under `04-Literature/Deep-Reads/`. The file is **untracked** at the 2026-08-17 fetch (Robin has not yet committed it — same state as the 2026-08-13 + 2026-08-15 fetches, 0 progress in the 2026-08-13 → 2026-08-17 96-hour window). **Watchlist trigger met at this fetch**: per the 2026-08-15 watchlist-trigger rubric ("if the file remains uncommitted at the next fetch (2026-08-17 or later), the structural signal weakens"), the `Review/` subfolder at the 2026-08-17 fetch is **still single-entry, still untracked** — the structural signal **does weaken** at this fetch (4-day carry-forward with no commit, no follow-up paper landed in the subfolder). The `Review/` subfolder is more likely to be a one-off than a recurring pattern. The file should either be committed on a future fetch (which would re-strengthen the signal) or remain untracked indefinitely (which would confirm the one-off interpretation). No synthesis routes until the file is committed.
- **`templates/` subfolder — first entry (2026-08-16, NEW this run)** — `templates/类器官IRB申请清单.md` (180 lines, mtime 2026-08-16, untracked) is the **first file in a new `templates/` directory** at the vault root. The file is Robin's **first customer-facing sales ammunition template produced from a single deep-read** (the Guo 2026 IRB ethics systematic review). Content: 7 mandatory IRB review points checklist (样本来源/知情同意/数据隐私/共培养主体性/3R 动物福利/跨境监管/长期保存与终止使用) + 5 customer Q&A ("类器官研究要不要 IRB 申请?" / "类器官共培养产品怎么申请 IRB?" / "类器官跨境研究怎么报?" / "3R 原则怎么写?" / "类器官 + 免疫细胞共培养 = CAR-T 体外培养, 算不算新生物体? 伦理上算什么?") + China vs International flow comparison table + 10-row 申请附件清单 + 7 references (Guo 2026 + ISSCR 2021 + OHRP 2016 + GDPR 2018 + China 2023 + China 2019 + Cambridge 2020). The template's `version: v1.0 (2026-08-16, Robin 8-16 实战沉淀)` and `Robin 业务定位: 类器官厂家给三甲医院 IRB 申请的标准模板 + Robin 客户培训材料核心` framing makes it explicit that this is the canonical "Robin 培训客户 IRB 申请" core material. **Structural significance**: the `templates/` directory is new — none of the existing top-level folders (`01-Active-Sales/` / `02-Clients/` / `02-Active-Deals/` / `02-Contacts/` / `03-Product/` / `03-Resources/` / `04-Literature/` / `05-Documents/` / `06-Sales/` / `99-Templates/` / `memory/`) provides a vendor-agnostic customer-training-artifact slot at the vault root. The Obsidian vault already has `99-Templates/` for reusable Obsidian templates (note templates, daily-report templates — per `99-Templates/` size hint 14 .md), but the new `templates/` directory is **for customer-facing sales ammunition**, not Obsidian note templates — a different artifact type. The naming convention overlaps with `99-Templates/` and may need disambiguation; Robin's intent (per the file header) is for this `templates/` to be the **canonical customer-training artifact directory**, distinct from `99-Templates/` Obsidian-note templates. **Customer-entry scenarios** called out in the template: (a) 类器官厂家研发负责人 = IRB 申请准备, (b) Robin 客户开发 = 培训客户 IRB 申请核心材料, (c) 医院 IRB 委员会 = 类器官研究 IRB 审查标准参考, (d) 学术合作方 = 跨境合作时多国法规差异对照. **Carry-forward status** (2026-08-17): untracked, future-commit candidate. **Track on next fetch** whether (a) Robin commits the file to `main`, (b) more templates land in the directory (extending the customer-training-artifact slot), (c) the `templates/` and `99-Templates/` naming overlap gets resolved (rename / docs / conventions). Synthesis routes into `/themes/05-robin-research.md` (sales ammunition pipeline section).
- **`celvivo_commercial/` subfolder — first entry (2026-08-17, NEW this run)** — `celvivo_commercial/1331651_20260630_131201.pdf` (56 KB PDF, mtime 2026-08-17, untracked) is the **first file in a new `celvivo_commercial/` directory** at the vault root. The PDF is the existing 6-30 quote PDF that Robin migrated into a new folder. The file is **a quote PDF**, not a synthesis target — the on-disk evidence is the existing 6-30 quote document that already exists in `05-Documents/Products/Celvivo/Industrial-Customers/` (per the 2026-08-15 synthesis-policy section above, "commercial docs (8 files: Exhibit 1 Price Book / Exhibit 3 SuperUser certification / Huibai demo discount agreement / 惠百 PO 盖章版 / Celvivo Distribution Agreement 2026 Huibai Bio / 1331651_20260630_131201 (6-30 quote) / Packing Slip Ordre 726_1 / Packing Slip Ordre 726_2)"). **Structural significance**: the `celvivo_commercial/` directory is new — Robin has migrated the 6-30 quote out of wherever it was previously (presumably a working folder or `05-Documents/Products/Celvivo/` deep path) into a top-level dedicated directory. **The migration is unfinished** — only 1 file in the new directory; if Robin intends the directory to consolidate all 8 commercial docs from `05-Documents/Products/Celvivo/Industrial-Customers/`, the other 7 files (Exhibit 1 Price Book / Exhibit 3 SuperUser certification / Huibai demo discount agreement / 惠百 PO 盖章版 / Celvivo Distribution Agreement 2026 / Packing Slip Ordre 726_1 / Packing Slip Ordre 726_2) should eventually land here too. **No synthesis routes** until Robin commits the file or migrates more docs into the directory. Carry-forward status (2026-08-17): untracked, single-entry, future-commit candidate. Track on next fetch whether (a) the file gets committed, (b) more commercial docs migrate into the directory.
- **2026-08-15 sources-sync bug — count-data wipe (operational)** — the `2507925e27b83b4f9d2e6f3b9c939d081a90f9f2` `chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-15)` commit at 2026-08-15 +0800 02:31 committed **empty count values** for NocoDB / Wiki.js / RAGFlow (SeaFile was already empty so the commit was a no-op there): (a) NocoDB: 6614 → **0** total records, with all 13 per-table counts (brain_organoid_literature / intestinal_organoid_literature / Celvivo_literature / cardiac_organoid_literature / cancer_organoid_literature / liver_organoid_literature / other_organoid_literature / kidney_organoid_literature / retinal_organoid_literature / Cellink_literature / organoid_literature_old / lung_organoid_literature / 3Brain_literature) cleared to empty cells; (b) SeaFile: libraries table unchanged (was empty in `1737454` already — a separate, older cron issue not introduced by `2507925`); (c) Wiki.js: 83 → **0** unique pages, ID range 22..1704 → **0..0**, Locale 分布 → empty, Top-level 路径分布 → empty; (d) RAGFlow: landing 200 → **000**, `/api/v1/health` 404 → **000**, `/api/v1/datasets` 401 → **000**. The header lines on each affected `/sources/{nocodb,ragflow,seafile,wikijs}.md` page still report `上次同步: 2026-08-14T18:30:42Z` (the prior successful sync timestamp), but the body count values are wiped. **Probable root cause**: the auto-source-sync CRON job ran but the underlying NocoDB / Wiki.js / RAGFlow API calls failed (likely the same operational issue already documented on `/sources/web-search.md` and `/sources/README.md` — runtime registry disagreement on `enabled: true` vs. disabled); the script committed the empty values instead of skipping the commit on failure. **Impact**: 3 source pages now show misleading zero/null values (NocoDB / Wiki.js / RAGFlow); Tavily / HN / git-repo synthesis is unaffected. **Recovery**: the wiped data is recoverable from the prior wiki commit (`git show 1737454:sources/nocodb.md` etc. will restore the pre-wipe state). This run restored the wiped data on all 3 affected pages (plus an operational note documenting the bug) so the wiki is internally consistent again. **Wiki-synthesis concern**: **none** — the synthesis layer (themes / commitments / open-questions / personal-logistics) is independent of the source-page counters. **Operational concern**: **yes** — the auto-source-sync job should (a) check connectivity before committing, (b) skip the commit on API failure rather than committing empty values, or (c) preserve the prior counter values when a fresh pull returns null/empty. Recorded for traceability here + on each affected `/sources/{nocodb,ragflow,seafile,wikijs}.md` page.
- **Liang 2026 liver organoid fibrosis platform (2026-08-12)** — `04-Literature/Deep-Reads/Liver/2026-08-12_Liang_2026_SciRep_liver_organoid_fibrosis_platform.md` (170 lines; `[[MOC-类器官与3D培养]]` already names this paper via `related:` back-link). The paper is **the net-new external evidence** this run (git-repo-1 2026-08-12) brought into the vault; see synthesis at `/themes/01-organoid-equipment.md` § CelVivo evidence (added 2026-08-12) and `/commitments.md` `liang-2026-celvivo-clinostar-positioning`. Single-paper LDR cycle: 4 commits (`e542c977` → `8699a154` → `aacba7aa` → `297f106d`) walked Robin's standard 3-stage SOP on the same file (186 lines → 105+/122- page 946 rewrite → page 934 修齐 micro-revisions). The 4-star "与我们的产品" table on the paper lists **CelVivo ClinoStar ⭐⭐⭐⭐** (P1-P10 长程扩增对应旋转培养 30+ 天无剪切; HSC 静止态在模拟微重力下 7+ 天维持) + **CelVivo ClinoReactor ⭐⭐⭐⭐** (单组织 3 轨道分通道灌流; TGFβ 时间程序精确切换) — **parallel CelVivo ClinoStar rating 5 to Miao 2025 v2's ClinoStar rating 5** from the 2026-08-08 flywheel-sync, but for liver organoid (long-term maturation + fibrosis modeling) rather than lung organoid (vascularization). 7 SeaFile Fig (Fig1-7) + 4-paper 参考文献 (Huch 2013 / Huch 2015 / Clevers 2016). Customer-entry: 药企临床前 (抗纤维化药筛) + 临床肝活检中心 (1-2 mg → 3 周药敏) + 学术 PI (2D vs 3D 旋转 efficiency). **MOC linkage**: the paper's `related:` field already names `[[MOC-类器官与3D培养]]` (the first MOC, created 2026-08-10) — confirming the MOC pattern is in active use on real deep-reads.
- **CelVivo industrial customers program** — a dedicated subfolder under
  `05-Documents/Products/Celvivo/Industrial-Customers/` holds `CelVivo_中国工业
  客户开发研究报告` (v1 + v2), `客户管线定位_1页图`, and `工业客户开发手册-v3`.
  This is a self-contained CelVivo China commercial effort.
- **CelVivo sales training cluster** — `06-Sales/Content/Training-Materials/`
  contains a `Robin稿生成通字稿` family (v3–v6), a `CelVivo赋能培训` PowerPoint
  family (v1–v9, depth-flavored edits), and a `销售基础话术包` pair. Versions
  progress from 基础 → 5大管线 → 深度版 → 终稿修正 → 销量仅看.
- **3Brain end-customer dossier set** — 11+ dossiers under
  `03-Resources/End-Customers/` covering 神经所 (上海), 北京大学, 北京天坛医院,
  浙大一附院, 中科院昆明动物所, 西南医科大学, 贵州医科大学, plus TCM accounts
  at 云南中医药大学 and 天津创新中药.
- **CelVivo distributor technical contact (2026-07-28, partially resolved
  2026-08-07)** — `02-Clients/Agents/董慧群.md` is the first profile under
  the `02-Clients/Agents/` bucket (frontmatter `type: agent`, role:
  代理商技术同事, products: CelVivo ClinoStar / ClinoReactor). The
  2026-08-07 `_known_associations.md` index now identifies the CelVivo
  dealer as **济南成全生物科技 (曹沛起)** — the only ClinoStar agent in
  the 259-dealer list, registered in both 华北 + 山东. Robin still needs
  to confirm: (a) is 董慧群 the same agency? (b) phone / WeChat / served
  end-customers / opportunities. The agency-side gap is now closed.
- **ITX 24h host build (first observed 2026-07-31; still untracked)** —
  `03-Resources/ITX-24h-Host/ITX_24h_Host_v18_Config_2026-07-31.md` is a
  top-level bucket first observed between the 2026-07-30T18:13 fetch and the
  2026-07-31T18:08 fetch; it remains untracked. Single file: Robin's personal
  24h server build plan for hosting Hermes Agent + AI workflow stack — mATX +
  i5-12400 + DDR4-2666 32G + 板载 Realtek 1Gb + Intel PRO/1000 GT 双网卡 NAS
  隔离, ¥2,985.82, 10/11 parts arrived, planned hostnames/roles:
  192.168.31.100 (主力机 SSH) vs 10.10.10.254 (RAGFlow / NAS RAGFlow API).
  Workflow-tooling priority LOW (not vendor-anchored), so it does **not** earn a
  `/themes.md` row, but the build remains a source-anchored personal-infra work
  item and was promoted to `/commitments.md` as
  `itx-24h-host-build-2026-q3` (Owner: me) for the post-assembly steps (Ubuntu
  Server 22.04 install + 双网卡静态 IP + Hermes Agent install + 24h soak test).
- **Cells + 2026-08-08 cluster** — Fernandez Vallone 2026 Cells (hiPSC
  brain organoids for THSDC chemical screening, NAMs platform) is the
  first `04-Literature/Deep-Reads/Cells/` entry. New application domain
  (toxicology + NAMs) compared to the prior Brain / Cancer / Liver
  buckets. CelVivo + 3Brain application scenarios called out in tags.
- **Microbioreactor + 2026-08-07 cluster** — Rosero 2026 Front Bioeng
  Biotechnol Microbioreactor design Mini Review is the first
  `04-Literature/Deep-Reads/Microbioreactor/` entry. Cross-vendor
  adjacent (CelVivo ClinoStar / Cellink BIO X / FemtoBiomed CellShot).
  Landed in NocoDB `Robin_Picked_Papers` (PMID 42516424, Wiki.js ID
  1696).
- **Parfitt 2024 Nat Commun (DJ1 LOF midbrain organoid + PD)** —
  untracked file `04-Literature/Deep-Reads/Brain/2026-08-06_Parfitt_GM_et_al_NatCommun_2024_DJ1_LOF_midbrain_organoid_PD.md`
  (15,972 bytes, mtime 2026-08-06). DJ1 LOF through astrocyte lysosomal
  dysfunction → AGE → α-syn → DA neuron death; CelVivo + 3Brain
  application scenarios in tags. Not yet on `main`; pending Robin
  commit.
- **CellSweep** — referenced in the wiki goal focus areas; not surfaced as a
  top-level vault folder in this run, so it likely lives under `Work/` or
  `scripts/` (outside the navigation index).
- **Phase A metadata batch + first MOC (2026-08-10)** — Robin ran a
  frontmatter-hygiene + MOC-discipline sprint on 2026-08-10:
  (a) **`d97b39ed` Phase A 批量** standardized 6 deep-read notes with the
  6-field frontmatter (doi / journal / year / **volume** / **pages** /
  **authors** array / pmid) — `Organoids 2026 review` +
  `CelVivo PAH Metabolomics` + `Shin 2024 thalamocortical organoids
  22q11ds` + `Fernandez Vallone 2026 Cells THSDC` + `Liu 2026 NBME
  shape-conformal organoid` + `类器官综述_CMOS_HD_MEA_类器官电生理_2026-06-05`;
  (b) **`6b717aef` MOC 方案 1 样品** created the **first MOC** at
  `04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md` (95 lines,
  沙牛《AI 时代的 Obsidian 公开课》课时 1 pattern, `type: moc`) and added
  `related:` back-link frontmatter to 7 papers; (c) **`3b929c2f` wang2024
  方案 2 样品** added 7 image alt descriptions on top of the 6-field
  frontmatter for `wang2024-org-on-chip.md`. The MOC's own `related:`
  list already names `[[MOC-3Brain-HD-MEA]]` as the next planned MOC,
  plus `[[02-Clients/Agents/_known_associations]]` and
  `[[02-Active-Deals/CellShot-TriArm-Demo-计划-v2-老师版-2026-07-20]]`,
  so the pattern is expected to extend. None of the changes add new
  external evidence — the 6 papers already existed on `main`; this
  commit set only normalizes their metadata and cross-references. The
  MOC creation is the first durable structural artifact on the
  knowledge-graph side and is worth tracking on the next git-repo
  fetch.

## Synthesis policy for this source

- **This run (2026-08-17, git-repo-1 18:09Z):** **7 new vault commits**
  landed in the 2026-08-15T18:07Z → 2026-08-17T18:09Z window — the vault
  HEAD bumped from `297f106d` (the 2026-08-12 Liang 2026 cluster) to
  `a4fa5a32` (the 2026-08-16 Quintard 2024 + Guo 2026 cluster). The
  cluster breaks down as: (a) **Quintard 2024 Nat Commun 4-commit LDR
  cycle** (`0fc8db24` adds 189 lines → `290e9635` -v2 修图床/双 H1/落款
  → `24c713de` -v3 Wiki.js 自带图床 6 张图 → `4073abf4` -v4 转发语标题/
  落款加粗/删 3Brain) on `obsidian-vault/Literature/Deep-Reads/Organoid/quintard_2024_vasorganoid_chip.md`;
  (b) **Guo 2026 Front Cell Dev Biol 3-commit LDR cycle** (`2e6f5989`
  adds 170 lines → `00f824f2` -v2 修图床 (加 2 张 Wiki.js 自带图) →
  `a4fa5a32` -v3 补 Fig 1) on
  `obsidian-vault/Literature/Deep-Reads/Organoid/guo_2026_organoid_ethical_review.md`.
  The 2026-08-16 cluster is **the first time since the 2026-07-28 /
  2026-07-29 Parate / Lee / Hodge cluster** that two new paper deep-reads
  landed on `main` in the same 48-hour window, and **the first time a
  review-type IRB / ethics systematic review (Guo 2026) was deep-read**
  in any vault window. **2 new untracked directories** appeared in
  the working tree this fetch: (a) `celvivo_commercial/1331651_20260630_131201.pdf`
  (the 6-30 quote PDF migrated into a new folder); (b) `templates/类器官IRB申请清单.md`
  (the IRB application checklist Robin produced from the Guo 2026
  review — Robin's **first customer-facing sales ammunition template**
  derived from a single deep-read). The 23 untracked working-tree
  files from the 2026-08-13 fetch are unchanged at this fetch (the
  `Review/zhou2023_computer_vision_microfluidics.md` first-entry-in-Review/-subfolder
  is still untracked, now a **4-day carry-forward** with watchlist
  signal weakening per the Notable-entity entry). Wiki-side: **4 new
  wiki commits** landed (`151d22b` daily update 2026-08-16 +
  `997b648` sources-sync 2026-08-16 + `5c70881` daily update 2026-08-17
  (created the new `sources/openwiki-version-drift.md` auto-generated
  page) + `be49285` sources-sync 2026-08-17), advancing HEAD from
  `2507925` (2026-08-15) to `be49285` (2026-08-17). 9 dirty wiki files
  in the working tree (`.last-update.json` + `quickstart.md` +
  `sources/README.md` + `sources/hackernews.md` + `sources/nocodb.md`
  + `sources/ragflow.md` + `sources/seafile.md` + `sources/web-search.md`
  + `sources/wikijs.md`) are **accumulated** synthesis-layer edits
  from the prior HN-1 2026-08-15 + HN-1 2026-08-16 + HN-1 2026-08-17 +
  web-search-1 2026-08-15 + web-search-1 2026-08-17 + git-repo-1
  2026-08-15 runs that are pending the next CLI orchestration commit
  (down from 10 dirty files at the 2026-08-15 fetch — `sources/index.md`
  got committed in the `151d22b` 2026-08-16 daily update). One
  **new wiki file** added in the window: `sources/openwiki-version-drift.md`
  (auto-generated OpenWiki version drift monitor; reports `v0.3.1` local
  → `v0.3.3` npm latest as of 2026-08-15T20:00:03Z with a manual
  `npm install -g openwiki@latest` action and a WARNING that v0.3.1 →
  v0.4+ may have breaking changes; the page is informational, not a
  synthesis target). **No `/commitments.md` row, no
  `/open-questions.md` row, no `/personal-logistics.md` item**
  added this run beyond the canonical synthesis pipeline — the
  Quintard 2024 deep-read has no existing synthesis page yet (the
  deep-read pipeline currently only carries `liang-2026-celvivo-clinostar-positioning`
  + `miao-2025-celvivo-clinostar-positioning` + `liu-2026-hd-mea-roadmap-implication`
  + `sharma-2026-retinal-organoid-mea-cross-sell`); the Guo 2026 IRB
  review is the first ethics-side deep-read and the IRB checklist
  template is the first customer-facing sales ammunition template,
  both of which warrant a commitment + a synthesis page on a future
  fetch. Wiki edits this run: (a) `/sources/git-repo.md` (this page)
  — refreshed frontmatter HEAD pointers (vault HEAD `297f106d` →
  `a4fa5a32`, wiki HEAD `2507925` → `be49285`, tags + `2026-08-17`,
  timestamp → `2026-08-17T18:09:32Z`), refreshed the Connector / State
  section to the new `2026-08-17T18-09-32-895Z` raw manifest, refreshed
  the obsidian-vault working-tree-status section to 2026-08-17 (7 new
  vault commits, 2 new untracked dirs, the `Review/zhou2023_computer_vision_microfluidics.md`
  carries forward as still-untracked), refreshed the
  Recent-commits-for-vault table to put the 7 new 2026-08-16 commits
  on top of the 2026-08-12 cluster, refreshed the openwiki-wiki
  working-tree-status section to 2026-08-17 (4 new wiki commits + 9
  uncommitted synthesis-layer edits — `sources/index.md` got committed
  in `151d22b`), refreshed the Recent-commits-for-wiki table to put
  the 4 new 2026-08-16/2026-08-17 commits on top of the 2026-08-15
  cluster, refreshed the Summary-of-last-48-hours table to add the
  2026-08-15T18:07Z → 2026-08-17T18:09Z window data (7 vault commits /
  4 wiki commits / 9 uncommitted wiki files / 1 new wiki file +
  2 new untracked dirs + 4-day carry-forward on `Review/` subfolder),
  refreshed the Notable-entity section to add (a) "Quintard 2024
  microfluidic vascularized organoid chip" entry (with 4-star
  Mimetas/CelVivo/Emulate mapping), (b) "Guo 2026 organoid ethics
  systematic review" entry (with 4-star Mimetas/CelVivo/Emulate
  mapping + IRB checklist template cross-link), (c) refreshed
  "Review/ subfolder" entry with watchlist-trigger-met note, (d)
  new "templates/ subfolder" entry (first customer-facing sales
  ammunition template), (e) new "celvivo_commercial/ subfolder" entry
  (the 6-30 quote PDF migration), refreshed the Synthesis-policy
  section with this run's delta summary. **No `/themes.md` row change**
  — the new external evidence routes into the existing
  `class-organoid-3d-bioprinting` theme row (Quintard 2024 is
  organ-on-chip adjacent to Robin's 4 application domains; Guo 2026
  is IRB-side adjacent to the same row); the Robin-authored
  IRB checklist template routes into the existing
  `/themes/05-robin-research.md` "Sales ammunition pipeline" section
  rather than a new theme row. **No `/open-questions.md` row, no
  `/personal-logistics.md` item** — the IRB checklist is a
  vendor-anchored customer-training artifact, not a memory-graph
  uncertainty. (b) `/themes/05-robin-research.md` — vault-snapshot
  metadata refreshed (fetch timestamp → `2026-08-17T18:09:32Z`,
  raw-manifest path → the new `2026-08-17T18-09-32-895Z` manifest;
  vault HEAD `297f106d` → `a4fa5a32`; untracked-dir set refreshed
  with `celvivo_commercial/` + `templates/` entries; `04-Literature/Deep-Reads/Organoid/`
  count `659` → `661` (Quintard + Guo); 30-day research output
  table extended with the 2026-08-16 Quintard 2024 + Guo 2026 row;
  by-vendor table extended with `Microfluidic / organ-on-chip
  adjacent` and `Ethics / IRB` rows; Sales ammunition pipeline section
  extended with the `templates/类器官IRB申请清单.md` IRB checklist
  template). (c) `/themes/01-organoid-equipment.md` — Quintard 2024
  added to CelVivo evidence anchors (CelVivo ClinoStar rating 3
  upstream workflow step) and Guo 2026 added to the Regulatory /
  China-specific context section (CelVivo ClinoStar rating 4 IRB
  compliance ammunition; companion to the existing CDE classification
  + Order No. 818 items). (d) `/sources/literature.md` — Quintard 2024
  + Guo 2026 added to the 30-day deep-read index. (e) `/sources/README.md`
  — git-repo last-updated refreshed from `2026-08-15 18:07 UTC` to
  `2026-08-17 18:09 UTC`. (f) `/quickstart.md` — added the
  "Latest update — git-repo-1 (2026-08-17T18:09Z)" paragraph. Wiki-side: **4 new wiki commits** landed (`021e929` daily
  update 2026-08-14 + `6258717` sources-sync 2026-08-14 + `173b58c`
  daily update 2026-08-15 + `2507925` sources-sync 2026-08-15),
  advancing HEAD from `1737454` (2026-08-13) to `2507925` (2026-08-15).
  **One operational issue** was surfaced by `2507925`: the 2026-08-15
  sources-sync committed **empty count values** for NocoDB / SeaFile /
  Wiki.js / RAGFlow (NocoDB 6614 → 0, Wiki.js 83 → 0, RAGFlow landing
  200 → 000) — see Notable-entity § "2026-08-15 sources-sync bug"
  below. 10 dirty wiki files in the working tree
  (`.last-update.json` + `quickstart.md` + `sources/README.md` +
  `sources/hackernews.md` + `sources/index.md` + `sources/nocodb.md` +
  `sources/ragflow.md` + `sources/seafile.md` + `sources/web-search.md`
  + `sources/wikijs.md`) are **accumulated** synthesis-layer edits
  from the prior HN-1 2026-08-13 + HN-1 2026-08-15 + web-search-1
  2026-08-15 + this git-repo-1 2026-08-15 runs that are pending the
  next CLI orchestration commit. Wiki edits this run: (a)
  `/sources/git-repo.md` (this page) — refreshed frontmatter HEAD
  pointers (vault HEAD unchanged, wiki HEAD `1737454` → `2507925`,
  tags + `2026-08-15`, timestamp → `2026-08-15T18:07:49Z`), refreshed
  the Connector / State section to the new
  `2026-08-15T18-07-49-711Z` raw manifest, refreshed the obsidian-vault
  working-tree-status section to 2026-08-15 (no new untracked files;
  the `Review/zhou2023_computer_vision_microfluidics.md` carries
  forward as still-untracked), refreshed the openwiki-wiki
  working-tree-status section to 2026-08-15 (4 new wiki commits + 10
  uncommitted synthesis-layer edits + the count-data wipe surfaced in
  the Notable-entity section), refreshed the recent-commits table with
  the 4 new wiki commits on top of the prior 2026-08-13 cluster,
  refreshed the Summary-of-last-24-hours table with the 2026-08-13 →
  2026-08-15 window data (0 vault commits / 4 wiki commits / 10
  uncommitted wiki files / operational issue row), refreshed the
  Notable-entity section to add a "2026-08-15 sources-sync bug"
  entry + carry-forward note on the `Review/` subfolder entry,
  refreshed the synthesis-policy section with this run's delta summary
  + the operational-issue observation; (b) `/themes/05-robin-research.md`
  — vault-snapshot metadata refreshed (fetch timestamp →
  `2026-08-15T18:07:49Z`, raw-manifest path → the new
  `2026-08-15T18-07-49-711Z` manifest); the vault HEAD pointer stays
  `297f106d` (unchanged across both 2026-08-13 and 2026-08-15 fetches);
  (c) `/quickstart.md` — added the "Latest update — git-repo-1
  (2026-08-15T18:07Z)" paragraph ahead of the current
  "Latest update — web-search-1 attempted 2026-08-15 skipped"
  paragraph; demoted the web-search-1 paragraph to a prior-run
  reference; updated the Backlog git-repo entry to reflect the new
  wiki HEAD `2507925` + 4 new wiki commits + 10 uncommitted files +
  the operational issue note.
  **No `/commitments.md` row, no `/open-questions.md` row, no
  `/personal-logistics.md` item, no `/themes.md` row change** — the
  vault delta is empty (no new commits, no new untracked files), and
  the existing 2026-08-12 Liang 2026 commitment /
  `class-organoid-3d-bioprinting` theme row already cover the
  structural evidence.
- **Previous run (2026-08-13, git-repo-1 18:08Z):** **0 new vault commits**
  in the 24-hour window — the vault HEAD was unchanged at `297f106d`
  (the 2026-08-12 Liang 2026 4-commit LDR cluster remained the most
  recent vault activity). The only vault-side delta was **1 new
  untracked file**: `04-Literature/Deep-Reads/Review/zhou2023_computer_vision_microfluidics.md`
  — the **first entry in a new `Review/` subfolder** under
  `04-Literature/Deep-Reads/` (see Notable-entity entry above). 1
  noise file (`__pycache__/...pyc`) was ignored. Wiki-side: **2 new
  wiki commits** landed (`8ddc6d9` daily update 2026-08-13 + `1737454`
  sources-sync 2026-08-13), advancing HEAD from `c57ead4` (2026-08-12)
  to `1737454` (2026-08-13). 8 dirty wiki files in the working tree
  were synthesis-layer edits from the prior HN-1 2026-08-13 run that
  landed after `1737454` committed and were pending the next CLI
  orchestration commit.
- **Previous run (2026-08-12, git-repo-1 18:08Z):** 4 new vault commits
  on the **same single Liang 2026 Sci Rep liver organoid paper** walked
  through Robin's standard 3-stage LDR cycle (`e542c977` adds file →
  `8699a154` page 946 9 项 SOP 重写版 → `aacba7aa` + `297f106d`
  page 934 修齐 micro-revisions) — this was the **net-new external
  evidence** for that run. Wiki edits at that time are described in
  the synthesis-policy paragraph above; the canonical synthesis
  continues to live at `/themes/01-organoid-equipment.md`,
  `/themes/05-robin-research.md`, and `/commitments.md`
  `liang-2026-celvivo-clinostar-positioning`.
- The vault is a knowledge base, not a live signal stream; durable
  per-document synthesis (paper deep reads, sales scripts, customer
  files) requires reading individual files, which is delegated to the
  Hermes skill and RAGFlow.
- Future runs should keep this page structural. Promote a row to a canonical
  theme only when the connector observes a recurring workflow (e.g. weekly
  literature digest cadence, sales training iteration pattern) across multiple
  fetches.
- **Process signal worth watching (2026-08-13):** (a) **New `Review/`
  subfolder signal** — Robin added a 20th subfolder under
  `04-Literature/Deep-Reads/` dedicated to review-type papers, with
  `zhou2023_computer_vision_microfluidics.md` as the first entry. If
  the subfolder accumulates ≥3 entries, this signals a formal
  review-paper stream is being built separately from the
  original-research stream; if it stays at 1 entry, it's a one-off.
  (b) **Liang 2026's MOC linkage confirms the MOC pattern is in active
  use** — the paper's `related:` field already names
  `[[MOC-类器官与3D培养]]` (the first MOC, created 2026-08-10) on the
  day of publication, not a future-state plan. Track on the next
  git-repo fetch whether more papers acquire MOC `related:` back-links
  and whether MOC-3Brain-HD-MEA / MOC-Cellink-BIO-X land. (c) **Page
  934 修齐 micro-revisions now appear on every new LDR cycle** —
  `297f106d` is the second paper (after `381fcbaa` OVB-organoids
  2026-08-11) where Robin applied the H1 去括号 / 元数据 bold /
  📄PDF 文件名 alignment. The pattern appears to be the new standard
  end-state. (d) **Phase A frontmatter batch rollout** is still
  paused (only 6 of ~1,204 deep-reads received the 6-field
  frontmatter); no progress this run.

## Next update

Run `openwiki_ingest_connector connectorId=git-repo` (or
`openwiki personal --update`) to refresh. Expect HEAD bump, refreshed
`recentCommits`, and updated working-tree status.