openwiki-wiki/sources/git-repo.md

type, title, description, resource, tags, timestamp

type	title	description	resource	tags	timestamp
Reference	Git repo — evidence index (Obsidian vault, Robin)	Compact manifest of Robin's Obsidian vault + the local OpenWiki wiki, ingested through the local git-repo connector. Two configured repos: obsidian-vault at /home/ldw/workspace (main branch, HEAD 9d4767c7, 2026-08-25, **5 new vault commits in the 2026-08-24T18:05Z → 2026-08-25T18:13Z 24-hour window — the SECOND consecutive single-day 5-paper LDR cluster: `089177a7` Tevonian 2026 Nat Commun vascularized liver MPS + `583859a8` Yang 2026 Stem Cell Res Ther cardiac organoid review + `9aa2af4c` Update Tevonian 2026 + Yang 2026 (CelVivo/Cellink/Mimetas/3Brain/FemtoBiomed product mapping retrofit + 净化 Robin mentions — the first post-publish vendor-mapping retrofit on the 2026-08-23/24/25 LDR cluster) + `5907cdfc` Shen 2026 Chin Med J vascularized organoids review + `9d4767c7` Zhai 2026 Sci Adv 3D skin pemphigus — combined with the 2026-08-23/24 5-paper burst, **10 papers in 48 hours = the largest sustained 2-day research output in Robin's vault activity log; the burst creates 3 new deep-read subfolders: `Vascularized-Organoids/` (Tevonian + Shen) + `Cardiac-Organoids/` (Yang) + `Skin-Organoids/` (Zhai)**; **vault HEAD unchanged at the 2026-08-26T18:06Z fetch** — 0 new vault commits since the prior 2026-08-25T18:13Z fetch, vault silent for the 1st consecutive fetch since the 2026-08-24/25 5-paper burst; the carry-forward untracked-file set bumps: `Review/zhou2023_computer_vision_microfluidics.md` 14-day → 15-day (12 → 13 fetches silent), `celvivo_commercial/` + `templates/` 9-day → 10-day, `deepread_40240593/` 2-day → 3-day) and openwiki-wiki at /home/ldw/.openwiki/wiki (main branch, HEAD ebb95c0a, 2026-08-26, **2 new automated wiki commits in the 2026-08-25T18:13Z → 2026-08-26T18:06Z window: `81ac94a` daily update 2026-08-26 + `ebb95c0` sources-sync 2026-08-26 — the twelfth consecutive sources-sync re-applying the 2026-08-15 count-data wipe pattern after `2507925` 2026-08-15 + `997b648` 2026-08-16 + `be49285` 2026-08-17 + `1fc73ae` 2026-08-18 + `dcb53a2` 2026-08-19 + `bd30339` 2026-08-20 + `f6c2576` 2026-08-21 + `43d4548` 2026-08-22 + `8f8f767` 2026-08-23 + `127c2dc` 2026-08-24 + `1003b92` 2026-08-25 + now `ebb95c0` 2026-08-26; the `81ac94a` daily update committed 14 of the prior 17 dirty files, reducing the working-tree dirty count from 11 → 8**) This page is a navigation index — content ingestion (paper deep reads, sales scripts, customer files) happens via the Hermes skill and RAGFlow, not here.	~/.openwiki/connectors/git-repo/config.json	git-repo evidence vault openwiki-wiki source 2026-08-26 2026-08-25 2026-08-24 2026-08-23 2026-08-22 2026-08-21 2026-08-20 2026-08-19 2026-08-18 2026-08-17 2026-08-15 2026-08-13 tevonian-2026-vascularized-liver-mps yang-2026-cardiac-organoid-review shen-2026-vascularized-organoids-review zhai-2026-3d-skin-pemphigus second-consecutive-cluster vascularized-organoids cardiac-organoids skin-organoids vault-silent-1d	2026-08-26T18:06:00Z

Git repo — evidence index (Obsidian vault + OpenWiki wiki)

Compact manifest of the two local git repos configured under the git-repo connector: Robin's Obsidian vault and the local OpenWiki wiki. This page is a navigation index — content ingestion (paper deep reads, sales scripts, customer files) happens via the Hermes skill and RAGFlow, not here. Keep this page terse and structural; it should help locate things in the vault, not summarize their content.

Connector

• Source instance: git-repo-1 (configured under ~/.openwiki/connectors/git-repo/config.json)
• Configured repos:
  • obsidian-vault → /home/ldw/workspace (Robin Obsidian vault, on main, HEAD 9d4767c7034a59d8f3206756c2dfeb3f4339c2e0 as of 2026-08-25 +0800 — 5 new vault commits in the 2026-08-24T18:05Z → 2026-08-25T18:13Z 24-hour window: the 2026-08-24/25 5-paper LDR cluster (SECOND consecutive single-day 5-paper LDR burst) — 089177a7 Tevonian 2026 Nat Commun 血管化肝 MPS deep read (PMID 41634021) + 583859a8 Yang 2026 Stem Cell Res Ther cardiac organoid review (PMID 41963991) + 9aa2af4c Update Tevonian 2026 + Yang 2026 (CelVivo/Cellink/Mimetas/3Brain/ FemtoBiomed product mapping retrofit + 净化 Robin mentions — the FIRST post-publish vendor-mapping retrofit on the 2026-08-23/24/25 LDR cluster) + 5907cdfc Shen 2026 Chin Med J vascularized organoids review (PMID 42268296) + 9d4767c7 Zhai 2026 Sci Adv 3D skin pemphigus (PMID 41512055). Combined with the 2026-08-23/24 5-paper burst, 10 papers in 48 hours = largest sustained 2-day research output in Robin's vault activity log. The cluster creates 3 new 04-Literature/Deep-Reads/ subfolders: Vascularized-Organoids/ (Tevonian + Shen) + Cardiac-Organoids/ (Yang) + Skin-Organoids/ (Zhai) — Robin expands the deep-read taxonomy from ~19 to ~22 per-vendor / per-application-domain subfolders in a single day. The new 9aa2af4c retrofit commit is the first synthesis-grade post-publish LDR touch on the 2026-08-23/24/25 cluster — the prior 5 papers (Ajongbolo + Kim + Tian + Aiello + CelVivo App Note) have NOT had this retrofit applied yet, only the new Tevonian + Yang pair get the retroactive 4-vendor mapping).
  • openwiki-wiki → /home/ldw/.openwiki/wiki (the OpenWiki knowledge base itself, on main, HEAD 1003b92f3a1e43197ec8e21e7f69fd5db38316e7 as of 2026-08-25T +0800 — 2 new wiki-side commits in the 2026-08-24T18:05Z → 2026-08-25T18:13Z 24-hour window: 3255613 chore: daily update 2026-08-25 + 1003b92 chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-25) — the eleventh consecutive sources-sync re-applying the 2026-08-15 count-data wipe pattern).
• Auth: local paths only — no remote, no credentials.
• Latest fetch: 2026-08-26T18:06:00Z (raw manifest ~/.openwiki/connectors/git-repo/raw/2026-08-26T18-06-29-420Z/manifest.json).
• Source config: ~/.openwiki/connectors/git-repo/config.json
• State: ~/.openwiki/connectors/git-repo/state.json records latestIds per repo; the 2026-08-26T18:06Z fetch observed vault HEAD unchanged at 9d4767c7 (same as the 2026-08-25T18:13Z fetch — 0 new vault commits in the 24-hour window, vault silent for the 1st consecutive fetch since the 2026-08-24/25 SECOND 5-paper burst; the 2026-08-25 5-paper cluster is the most recent vault activity, 1 calendar day stale), and observed openwiki-wiki bumped from 1003b92 (2026-08-25T18:13Z fetch) to ebb95c0a85b85e5abb8d11463cfa8b855c504e5f (2 new automated wiki commits in the 24-hour window: 81ac94a chore: daily update 2026-08-26 (2026-08-26T02:23 +0800; committed 14 of the prior 17 dirty files per git show --stat 81ac94a, reducing the working-tree dirty count from 11 → 8) + ebb95c0 chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-26, 2026-08-26T02:30 +0800 — the twelfth consecutive sources-sync re-applying the 2026-08-15 count-data wipe pattern after 2507925 2026-08-15 + 997b648 2026-08-16 + be49285 2026-08-17 + 1fc73ae 2026-08-18 + dcb53a2 2026-08-19 + bd30339 2026-08-20 + f6c2576 2026-08-21 + 43d4548 2026-08-22 + 8f8f767 2026-08-23 + 127c2dc 2026-08-24 + 1003b92 2026-08-25 + now ebb95c0 2026-08-26).

obsidian-vault — working-tree status (2026-08-26)

• Branch: main

• HEAD: 9d4767c7034a59d8f3206756c2dfeb3f4339c2e0 (vault HEAD unchanged from the 2026-08-25T18:13Z fetch — 0 new vault commits in the 2026-08-25T18:13Z → 2026-08-26T18:06Z 24-hour window, vault silent for the 1st consecutive fetch since the 2026-08-24/25 SECOND 5-paper burst; the 2026-08-25 5-paper cluster remains the most recent vault activity, 1 calendar day stale). The 2026-08-24/25 cluster is the SECOND consecutive single-day 5-paper LDR burst — combined with the 2026-08-23/24 5-paper burst (Ajongbolo + Kim + Tian + Aiello + CelVivo App Note), Robin has produced 10 LDR papers in 48 hours, the largest sustained 2-day research output in Robin's vault activity log. The cluster creates 3 NEW 04-Literature/Deep-Reads/ subfolders — Vascularized-Organoids/ (Tevonian + Shen) + Cardiac-Organoids/ (Yang) + Skin-Organoids/ (Zhai) — Robin expands the deep-read folder taxonomy from ~19 to ~22 in a single day. Crucially, the cluster includes the FIRST post-publish vendor-mapping retrofit commit (9aa2af4c) which adds CelVivo / Cellink / Mimetas / 3Brain / FemtoBiomed product mapping + 净化 Robin mentions to the Tevonian + Yang files — the prior 5 papers (Ajongbolo + Kim + Tian + Aiello + CelVivo App Note) have NOT had this retrofit applied retroactively.

• mtime activity in window: 0 new committed files in the 2026-08-25T18:13Z → 2026-08-26T18:06Z 24-hour window — vault is silent in this fetch; the 5-paper 2026-08-24/25 LDR cluster (4 new files + 1 retrofit commit) and the 5-paper 2026-08-23/24 LDR burst all carry forward unchanged from the prior fetches. The 3 NEW per-vendor / per-application-domain subfolders created in the 2026-08-24/25 burst all remain at the same counts: Tevonian_2026_Nat_Commun_Vascularized_Liver_MPS.md

  • Yang_2026_Stem_Cell_Res_Ther_Cardiac_Organoid_Review.md in Vascularized-Organoids/ + Cardiac-Organoids/ respectively + Shen_2026_Chin_Med_J_Vascularized_Organoids_Review.md second file in Vascularized-Organoids/ + Zhai_2026_Sci_Adv_3D_Skin_Pemphigus.md in Skin-Organoids/ — plus the Tevonian + Yang in-place M touches from the 9aa2af4c retrofit commit. The 2026-08-23 + 2026-08-24 LDR burst files (Ajongbolo + Kim + Tian + Aiello + CelVivo App Note
  • deepread_40240593/ pipeline workspace) all carry forward unchanged from the 2026-08-24T18:05Z fetch. The celvivo_commercial/
  • templates/ untracked dirs continue to carry forward (now 10-day carry-forward at this fetch — was 9-day at the 2026-08-25T18:13Z fetch). The Review/zhou2023_computer_vision_microfluidics.md first-entry file is unchanged from the 2026-08-25T18:13Z fetch (mtime 2026-08-11, 15-day carry-forward in the untracked set at this fetch — was 14-day at the 2026-08-25T18:13Z fetch; the structural signal continues to weaken per the Notable-entity entry on the Review/ subfolder — 13 fetches silent at this fetch, was 12 fetches silent at the 2026-08-25T18:13Z fetch).

• Ahead of origin/main: 30 commits new since 2026-08-03 fetch (+5 from the prior 25-commit baseline at the 2026-08-24T18:05Z fetch — the 5 new commits land on top of the 25-commit carry-forward; 5 new commits land on top of the 25-commit carry-forward, vault HEAD unchanged at the 2026-08-26T18:06Z fetch (vault silent for the 1st consecutive fetch since the 2026-08-24/25 5-paper burst; total remains 30 since 2026-08-03).

• Dirty: yes — the untracked file set is partially changed: the 8 × 02-Clients/Agents/区域-2026-0807.md distributor-rebuild files + 14 working-folder files + 2 untracked dirs from the 2026-08-17T18:09Z fetch carry forward unchanged, and the Review/zhou2023_computer_vision_microfluidics.md first-entry in the new Review/ subfolder is still untracked (Robin has not yet committed it) — 15-day carry-forward at this fetch (was 14-day at the 2026-08-25T18:13Z fetch); the structural signal continues to weaken per the Notable-entity entry on the Review/ subfolder (the subfolder has been a single-entry watchlist since 2026-08-13, now 13 fetches silent — was 12 fetches silent at the 2026-08-25T18:13Z fetch). The celvivo_commercial/ + templates/ untracked dirs continue to carry forward (now 10-day carry-forward at this fetch — was 9-day at the 2026-08-25T18:13Z fetch); the deepread_40240593/ untracked pipeline workspace also continues to carry forward (now 3-day carry-forward — was 2-day at the 2026-08-25T18:13Z fetch); no NEW untracked dirs at this fetch.

• Working-tree status (raw manifest, abbreviated):

  Status	Path
  A (committed 2026-08-12, e542c977)	04-Literature/Deep-Reads/Liver/2026-08-12_Liang_2026_SciRep_liver_organoid_fibrosis_platform.md — NEW external evidence (Liang Y et al. Sci Rep 2026 DOI 10.1038/s41598-026-42990-2, PMID 41857098, 3 轨道 Hep-Orgs + Cho-Orgs + HSC, DAPT+Dex P1-P10 长程成熟, TGFβ 激活体外纤维化模型; Wiki.js Id=1716, NocoDB Id=770, SeaFile PDF + 7 真图)
  M (committed 2026-08-12, 8699a154)	same Liang 2026 file — page 946 9 项 SOP 重写版 (105+/122- lines)
  M (committed 2026-08-12, aacba7aa)	same Liang 2026 file — frontmatter title 改中文 + 与正文 H1 一致 (1-line touch)
  M (committed 2026-08-12, 297f106d)	same Liang 2026 file — 修齐 page 934 标杆 (H1 去括号/元数据用bold/📄PDF文件名, 5+/4- lines)
  A (committed 2026-08-16, a4fa5a32)	obsidian-vault/Literature/Deep-Reads/Organoid/guo_2026_organoid_ethical_review.md — NEW external evidence (Guo Z, Zhang N 2026 Front Cell Dev Biol DOI 10.3389/fcell.2026.1721946 — IRB / ethics systematic review; Wiki ID 1724, NocoDB Id 3298, 170 lines + 3 张真图; "与我们的产品" table lists CelVivo ClinoStar ⭐⭐⭐⭐ [临床转化类器官的伦理合规——7 大要点直接适用 IRB 申请] + Mimetas OrganoPlate ⭐⭐⭐⭐ [类器官 + 免疫细胞共培养伦理审查依据] + Emulate Organ-Chip ⭐⭐⭐; 3 commits 2e6f5989 → 00f824f2 → a4fa5a32 = adds → -v2 修图床 → -v3 补 Fig 1)
  A (committed 2026-08-16, 0fc8db24)	obsidian-vault/Literature/Deep-Reads/Organoid/quintard_2024_vasorganoid_chip.md — NEW external evidence (Quintard C et al. 2024 Nat Commun DOI 10.1038/s41467-024-45710-4 — microfluidic platform for vascularized organoid chips; Wiki IDs 1719/1720/1722, NocoDB Id 3297; 4 commits 0fc8db24 → 290e9635 → 24c713de → 4073abf4 = adds 189 lines → -v2 修图床/双 H1/落款 → -v3 Wiki.js 自带图床 6 张图 → -v4 转发语标题/落款加粗/删 3Brain; "与我们的产品" table lists Mimetas OrganoPlate ⭐⭐⭐⭐ [直接对标: Phaseguide 微流控技术用于血管化/肾/肠 organ-on-chip] + CelVivo ClinoStar ⭐⭐⭐ [类器官前段成熟期培养: BVO 在 hiPSC 分化到 day 15 需要悬浮旋转培养, ClinoStar 是该步骤的金标准; day 15 后才转入芯片, ClinoStar 是完整工作流的前置] + Emulate Organ-Chip ⭐⭐⭐)
  M (committed 2026-08-10)	04-Literature/Deep-Reads/Organoid/2026-07-29_Organoids_disease_modeling_treatment_2026_review.md (Phase A batch frontmatter — volume / pages / authors array; also touched by 6b717aef for related back-link)
  M (committed 2026-08-10)	CelVivo_精读报告_04_bioRxiv_PAH_Metabolomics.md (Phase A batch frontmatter — volume / pages / authors array; also touched by 6b717aef)
  M (committed 2026-08-10)	obsidian-vault/04-Literature/Deep-Reads/3Brain/shin-2024-thalamocortical-organoids-22q11ds.md (Phase A batch frontmatter; also touched by 6b717aef)
  M (committed 2026-08-10)	obsidian-vault/04-Literature/Deep-Reads/Cells/fernandez-vallone-2026-thsdc-brain-organoids.md (Phase A batch frontmatter; also touched by 6b717aef)
  M (committed 2026-08-10)	obsidian-vault/04-Literature/Deep-Reads/NBME-ShapeConformal/literature-liu-2026-nbme-shape-conformal-organoid.md (Phase A batch frontmatter; also touched by 6b717aef)
  M (committed 2026-08-10)	类器官综述_CMOS_HD_MEA_类器官电生理_2026-06-05.md (Phase A batch frontmatter; also touched by 6b717aef)
  M (committed 2026-08-10)	04-Literature/Deep-Reads/wang2024-org-on-chip.md (方案 2 样品 — 6 frontmatter fields + 7 alt descriptions; also touched by 6b717aef)
  A (committed 2026-08-10)	04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md (方案 1 — first MOC file; 95 lines; 沙牛《AI 时代的 Obsidian 公开课》课时 1 pattern; related: already lists [[MOC-3Brain-HD-MEA]] as a forward link)
  ?? (untracked)	02-Clients/Agents/全国经销商地图-2026-0807.md + 7 区域 *2026-0807.md files (8-07 distributor baseline refresh — see below)
  ?? (untracked, NEW 2026-08-17)	celvivo_commercial/1331651_20260630_131201.pdf — NEW untracked directory; the 6-30 quote PDF Robin migrated into a new celvivo_commercial/ folder; companion to the existing 05-Documents/Products/Celvivo/Industrial-Customers/ commercial-docs subtree
  ?? (untracked, NEW 2026-08-17)	templates/类器官IRB申请清单.md — NEW untracked directory; the IRB application checklist derived from the Guo 2026 ethics-review deep-read (180 lines; 7 mandatory points [样本来源/知情同意/数据隐私/共培养主体性/3R 动物福利/跨境监管/长期保存与终止使用] + 5 customer Q&A + China vs International flow table + 10 attachments + 7 citations); Robin's first customer-facing template derived from a single deep-read — materializes the "Robin 业务定位: 类器官厂家给三甲医院 IRB 申请的标准模板 + Robin 客户培训材料核心" framing from the Guo 2026 deep-read
  ?? (untracked)	04-Literature/Deep-Reads/Brain/2026-08-06_Parfitt_GM_et_al_NatCommun_2024_DJ1_LOF_midbrain_organoid_PD.md
  ?? (untracked)	Liu2026_NBME_shape_conformal_organoid.md
  ?? (untracked)	Miao2025_Cell_v2.md
  ?? (untracked)	Miao2025_Cell_vascularized_organoid.md
  ?? (untracked)	Microbioreactor_2026_Rosero_FrontBioeng.md
  ?? (untracked)	__pycache__/literature_deepread_v6.cpython-312.pyc — NEW (2026-08-13) Python compiled cache file (build noise from running literature_deepread_v6.py, ignored)
  ?? (untracked)	dify精读进度-20260805.md
  ?? (untracked)	literature_deepread_v6.py
  ?? (untracked)	obsidian-vault/04-Literature/Deep-Reads/Review/zhou2023_computer_vision_microfluidics.md — NEW (2026-08-13) first entry in the new Review/ subfolder (Zhou 2023 computer vision + microfluidics — Robin deep-read in progress, untracked, future-commit candidate)
  ?? (untracked)	obsidian-vault/rustdesk-selfhosted-2026-08-05.md
  ?? (untracked)	retinal_organoid_deep_read_2026-08-07.md
  ?? (untracked)	文悦精读流水线.yml + v2/v3/v4/v5-clean variants

  The 8 untracked *2026-0807.md files in 02-Clients/Agents/ are the 2026-08-07 distributor baseline refresh — see the "Distributor map refresh (2026-08-07)" section below for synthesis. The 2 NEW untracked files this fetch are: (a) Review/zhou2023_computer_vision_microfluidics.md — first entry in a new deep-read subfolder (see Notable-entity entry below); (b) __pycache__/...pyc — build noise, ignored.

Recent commits (latest first)

Date	Hash	Note
2026-08-25	9d4767c7	feat: Zhai 2026 Sci Adv 3D skin pemphigus (PMID 41512055) — adds obsidian-vault/04-Literature/Deep-Reads/Skin-Organoids/Zhai_2026_Sci_Adv_3D_Skin_Pemphigus.md — FIRST file in the new Skin-Organoids/ subfolder, single-shot LDR entry. Zhai T et al. Sci Adv 2026 — 3D skin organoid + pemphigus disease-modeling application domain; net-new application domain (autoimmune dermatology + 3D skin) to Robin's deep-read set, distinct from cancer organoid (cancer) / brain organoid (Raji 2026 etc.) / vascularized organoid (Tevonian + Shen in this cluster) / cardiac organoid (Yang in this cluster) / liver organoid (Liang 2026) / brain-tumor organoid buckets. Vendor anchor mapping: TBD on the wiki-side synthesis page; skin organoid is adjacent to CelVivo ClinoReactor (long-term 3D skin culture) but no vendor callouts confirmed in the manifest entry. Future implication: skin organoid is a candidate workflow for the Robin CelVivo industrial-customers program (cosmetic + dermatology pharma R&D).
2026-08-25	5907cdfc	feat: Shen 2026 Chin Med J vascularized organoids review (PMID 42268296) — adds obsidian-vault/04-Literature/Deep-Reads/Vascularized-Organoids/Shen_2026_Chin_Med_J_Vascularized_Organoids_Review.md — FIRST review-type file in the new Vascularized-Organoids/ subfolder, single-shot LDR entry. Shen Y et al. Chin Med J 2026 — vascularized organoid systematic review (peer-reviewed Chinese-language journal); companion to the Tevonian 2026 vascularized liver MPS deep-read in the same cluster. Vendor anchor mapping: TBD on the wiki-side synthesis page; vascularized organoid literature is CelVivo ClinoStar-adjacent (long-term stable vascular maturation) + Mimetas OrganoPlate-adjacent (organ-on-chip for vascularized microenvironment) + Cellink BIO X-adjacent (decellularized scaffold for vascularization).
2026-08-25	9aa2af4c	Update Tevonian 2026 + Yang 2026: add CelVivo/Cellink/Mimetas/3Brain/Femtobiomed product mapping + 净化 Robin mentions — M touches obsidian-vault/04-Literature/Deep-Reads/Cardiac-Organoids/Yang_2026_Stem_Cell_Res_Ther_Cardiac_Organoid_Review.md + M touches obsidian-vault/04-Literature/Deep-Reads/Vascularized-Organoids/Tevonian_2026_Nat_Commun_Vascularized_Liver_MPS.md — FIRST post-publish vendor-mapping retrofit commit in Robin's LDR pipeline; the prior 5-paper 2026-08-23/24 cluster (Ajongbolo + Kim + Tian + Aiello + CelVivo App Note) did NOT have this retrofit applied retroactively; only the new Tevonian + Yang pair get the retroactive 5-vendor mapping (CelVivo + Cellink + Mimetas + 3Brain + Femtobiomed) plus 净化 Robin mentions. Robin's LDR SOP iteration: the 5-vendor product-mapping table is now a standard post-publish step for new LDR commits. The 净化 Robin mentions specifically removes any direct attribution strings ("Robin"s, "Robin 8-XX 实战沉淀" patterns, etc.) that might leak into the production deep-read narrative.
2026-08-25	583859a8	feat: Yang 2026 Stem Cell Res Ther cardiac organoid review (PMID 41963991) — adds obsidian-vault/04-Literature/Deep-Reads/Cardiac-Organoids/Yang_2026_Stem_Cell_Res_Ther_Cardiac_Organoid_Review.md — FIRST file in the new Cardiac-Organoids/ subfolder, single-shot LDR entry. Yang L et al. Stem Cell Res Ther 2026 — cardiac organoid review (companion to Tian 2025 Nat Commun cardiac epicardium mTOR paper from the prior 5-paper cluster). The new Cardiac-Organoids/ subfolder joins the existing Cardiac/ subfolder (2 prior papers) — Robin has expanded the cardiac application-domain treatment from a sparse 2-paper bucket to a dedicated subfolder. Vendor anchor mapping: TBD; the 9aa2af4c retrofit commit updated the file with the 5-vendor mapping (CelVivo + Cellink + Mimetas + 3Brain + Femtobiomed).
2026-08-25	089177a7	feat: Tevonian 2026 Nat Commun 血管化肝 MPS deep read (PMID 41634021) — adds obsidian-vault/04-Literature/Deep-Reads/Vascularized-Organoids/Tevonian_2026_Nat_Commun_Vascularized_Liver_MPS.md — FIRST file in the new Vascularized-Organoids/ subfolder, single-shot LDR entry. Tevonian et al. (2026) Nat Commun — vascularized liver MPS (microphysiological system) deep read. Companion to the existing Liver/ subfolder entries (Liang 2026 fibrosis platform etc.) — this adds the vascularization dimension to the liver organoid application-domain bucket. Vendor anchor mapping: TBD; the 9aa2af4c retrofit commit updated the file with the 5-vendor mapping (CelVivo + Cellink + Mimetas + 3Brain + Femtobiomed).
2026-08-23	fb017e4f	feat: CelVivo App Note 2026 shear stress ClinoStar vs orbital shaker (Wiki.js 1747) — adds obsidian-vault/04-Literature/Deep-Reads/CelVivo_Shear_Stress_AppNote_2026.md (10,145 bytes, single-shot entry) — NEW vendor-anchored CelVivo evidence: Stougaard Borgen Løschenkohl, Sedighi Frandsen (CelVivo App Note 2026) head-to-head ClinoStar® vs orbital shaker, 15-day HepG2/C3A + embedded Caco-2 + brain organoid; F-actin + DAPI staining shows ClinoStar preserves cytoskeleton integrity vs orbital shaker structural decay; ATP + BCA + 3 biological replicates per condition; SP5D 24-well ball-plate 1000 cells/aggregate pre-conditioning; ClinoReactor® vessel (CelVivo 10004-12) in ClinoStar® system (30003) vs ULA 6-well + Steinberg SBS-LVS-100 shaker; low-shear fFSS confirmation
2026-08-23	f2118a62	feat: Aiello & Bagni 2025 biorxiv Rotating Chamber brain organoid 精读 (Wiki.js 1746) — adds obsidian-vault/04-Literature/Deep-Reads/Aiello_Bagni_2025_biorxiv_Brain_Organoid_Fluid.md (11,731 bytes, single-shot entry) — NEW CelVivo-aligned evidence: EMBO Reports 投稿版 (Aiello_Bagni_EMBO R_050325) — COMSOL Multiphysics 6.2 CFD quantification of Rotating Chamber (RC) shear stress field; chamber geometry 78.3 mm × 24.2 mm (outer) / 37.7 mm × 8.8 mm (inner); shear stress < 20 mPa confirmed (vs qualitative "low-shear" only previously); 0-300 objects per chamber all stable low-shear across densities 1010/1020/1030; multi-batch + multi-iPSC line brain organoid morphology PCA (CV <15% vs static >30%); scRNA-seq OXPHOS profiling; SOX2/Nestin/PAX6 + DCX + TBR1/SATB2/MAP2 multi-marker IHC; first quantitative confirmation of CelVivo RC low-shear claim
2026-08-23	40b357b8	feat: Tian 2025 NatCommun 心外膜 mTOR 精读 (Wiki.js 1745) — adds obsidian-vault/04-Literature/Deep-Reads/Tian_2025_NatCommun_Epicardium_mTOR.md (15,578 bytes, single-shot entry) — NEW cardiac organoid evidence: Tian Y, Lucena-Cacace A, Tani K et al. (2025) Nat Commun DOI 10.1038/s41467-025-60934-8 — Torin1 (dual mTORC1/2 inhibitor, 200 nM) drives hiPSC epicardium maturation from embryonic to adult phenotype; qHSC→aHSC EMT reactivation pathway; bulk RNA-seq 379 DEGs; PCA explains 28.53% PC1 + 36.01% PC2 variance; co-culture hiPSC epicardium + ventricular cardiomyocyte EB → TNNI3 upregulation (paracrine maturation); mTORC1/2 dual inhibition is critical (Rapamycin alone insufficient); YBX3 + MAFF TF candidates via siRNA knockdown; first cardiac epicardium paper since MOC 心肌 maturation track started
2026-08-23	5f02489a	feat: Kim 2025 NatCommun 液态金属 3D MEA 精读 (Wiki.js 1744) — adds obsidian-vault/04-Literature/Deep-Reads/Kim_2025_NatCommun_Liquid_Metal_3D_MEA.md (13,567 bytes, single-shot entry) — NEW 3D-MEA / electrophysiology evidence: Kim E, Jeong E, Hong YM et al. (2025) Nat Commun DOI 10.1038/s41467-024-55752-3 — magnetically reshapable EGaIn (eutectic gallium-indium) liquid-metal 3D MEA pillar array via microfluidic direct-ink-writing; pillar height 25-310 µm linearly controlled by print speed (R²>0.95, n=12, SEM<5%); pillar diameter to 14 µm (single-neuron scale); parylene-C selective sidewall encapsulation (only tip conductive); hPSC cortical organoid 120-day maturation (dual-SMAD inhibition + FGF2/EGF + BDNF/NT3); 6-marker IHC (MAP2/GFAP/VGLUT1/SATB2/CTIP2) showing 6-layer cortical-like structure; Ni magnetic layer for magnetic reshaping; 64-channel MEA + SU spike + network synchronization; third flexible-electronics / 3D-MEA paper this cycle after Liu 2026 (NBME shape-conformal porous framework) + Sharma 2026 (60-channel MCS MEA retinal organoid) — direct 3Brain HD-MEA competitive pressure signal
2026-08-23	ad4abcde	feat: Ajongbolo 2025 Cells 脑类器官综述精读 (Wiki.js 1743) — adds obsidian-vault/04-Literature/Deep-Reads/Ajongbolo_2025_Cells_Brain_Organoids_Review.md (11,367 bytes, single-shot entry) — NEW brain-organoid review evidence: Ajongbolo AO, Langhans SA (2025) Cells DOI 10.3390/cells14110842 — comprehensive brain-organoid + assembloid review covering (i) whole-brain vs region-specific vs complex systems (assembloid + OoC + tumoroid + transplant); (ii) 4-tier characterization (morphological / biochemical / functional / omics); (iii) disease modeling across neurodevelopmental (microcephaly / macrocephaly / ASD / Rett / fragile X / Timothy syndrome) + neurodegenerative (AD / PD / HD / ALS) + brain tumor (glioblastoma / medulloblastoma / AT/RT); (iv) drug discovery + HTS pathways; first brain-organoid review since the 2026-07-29 Organoids 2026 disease-modeling review; mentions ClinoStar / orbital shaker reagent-supply chain
2026-08-16	a4fa5a32	literature: review 类 Guo 2026 -v3 补 Fig 1 — in-place update ID 1724, 3 张图全
2026-08-16	00f824f2	literature: review 类 Guo 2026 -v2 修图床 — in-place update ID 1724, 加 2 张 Wiki.js 自带图
2026-08-16	2e6f5989	literature: 精读 Guo 2026 Front Cell Dev Biol - 类器官伦理审查 (review 类, Wiki ID 1724, NocoDB Id 3298) — NEW external evidence (类器官研究 IRB / 伦理审查 7 大强制要点系统综述, 嘉兴市第一医院 + 嘉兴大学医学院视角)
2026-08-16	4073abf4	literature: 精读 Quintard 2024 -v4 — 转发语标题/落款加粗/删3Brain
2026-08-16	24c713de	literature: 精读 Quintard 2024 -v3 Wiki.js 自带图床 (ID 1722, 6 张图永久)
2026-08-16	290e9635	literature: 精读 Quintard 2024 -v2 修图床/双 H1/落款 (Wiki ID 1720)
2026-08-16	0fc8db24	literature: 精读 Quintard 2024 Nat Commun - 微流控血管化类器官芯片 (Wiki ID 1719, NocoDB Id 3297) — NEW external evidence (10 通道并行微流控 + hiPSC-BVO 30 天功能性灌注培养 + 跨类器官验证)
2026-08-12	297f106d	literature: 修齐 page 934 标杆 — H1 去括号 / 元数据用 bold / 📄PDF 文件名 (Liang 2026 v3)
2026-08-12	aacba7aa	literature: frontmatter title 改中文 + 与正文 H1 一致 (Liang 2026 v2)
2026-08-12	8699a154	literature: Liang 2026 Sci Rep liver organoid fibrosis - page 946 9 项 SOP 重写版 (Liang 2026 v2; 105+/122- lines; core-question / research-model / 6-finding 3-stage tables / 6 SeaFile Fig / "与我们的产品" 4-star / 4-paper refs / 转发语 / 完整落款)
2026-08-12	e542c977	literature: Liang 2026 Sci Rep liver organoid + fibrosis platform (Id=770 NocoDB) — NEW external evidence (3 轨道 Hep/Cho/HSC + DAPT+Dex P1-P10 长程成熟 + TGFβ 激活 HSC 体外纤维化模型; 7/7 Ollama qwen2.5vl 视觉审核通过; SeaFile 7/7 公网 200 验真; 飞轮 PATCH comm Id=87 + product Id=10 + NocoDB PATCH 770)
2026-08-10	d97b39ed	Phase A 批量：6 篇精读加 Front Matter 6 字段 (doi/journal/year/volume/pages/authors/pmid) — Organoids 2026 review + CelVivo PAH + Shin 2024 + Fernandez Vallone 2026 + Liu 2026 + 类器官综述_CMOS_HD_MEA
2026-08-10	3b929c2f	wang2024 方案 2 样品：6 个 Front Matter 字段 + 7 张图加 alt 描述 — wang2024-org-on-chip.md
2026-08-10	6b717aef	MOC 方案 1 样品：建 1 个 MOC + 7 篇加 Front Matter (related: 反链) — first MOC MOC-类器官与3D培养.md created; 7 papers got related: back-link frontmatter
2026-08-09	a14758b1	精读: Wang 2024 Theranostics 类器官-芯片综述 (7 张配图 + Wiki.js ID 1700) — first Organoid-on-Chip 综述 / 7 大主题板块
2026-08-08	d7df3830	cells paper v2: 双 H1 + 5张真图 (xref) — Fernandez Vallone 2026
2026-08-08	6c16dc05	精读: Fernandez Vallone 2026 Cells hiPSC 脑类器官 THSDC
2026-08-07	65fef021	fix: v2 with SeaFile links — Microbioreactor 2026
2026-08-07	18bee69f	feat: Microbioreactor design 2026 Front Bioeng Biotechnol Mini Review (PMID 42516424)
2026-08-08	1614ccf9	fix: v11 - forwarding per skill template (Liu 2026)
2026-08-08	a7cfb8a4	fix: final - per Research SOP strict + clean internal traces (Liu 2026)
2026-08-08	d1e8c6dd	fix: v5 - per Research SOP + page 946 benchmark (Liu 2026)
2026-08-08	b7882b81	fix: v4 - add forward message (Liu 2026)
2026-08-08	84e93402	fix: v3 - Fig 3 restored from page 6, audit table removed (Liu 2026)
2026-08-08	a69ad9c4	literature: liu 2026 NBME shape-conformal organoid
2026-08-08	1c05eee7	literature: miao 2025 cell organoid vascularization v2
2026-08-08	a0810433	精读: Sharma K 2026 Cell Stem Cell 视网膜类器官血管化RGC存活与功能成熟
2026-07-29	2341383e	fix(hook4): 湖北行去掉 'Robin 8 月出差高发地' 残留 (Robin 真实出差意图)
2026-07-29	aa8fd2bc	fix(hook4): 改标题 '下次出差' → '按 xlsx 缺口', Robin 后续自规划出差路径
2026-07-29	4b237a82	feat(hook): 4 个经销商管理 Hook 升级
2026-07-29	b9da34dc	fix(literature): Organoids 2026 综述 - 按 literature-deep-read-review SOP 重写
2026-07-29	0cd44fa0	feat(literature): 精读 Organoids for disease modeling and treatment 2026 综述
2026-07-28	642e3dc6	feat(agent): 新增代理商技术同事董慧群档案 (推 CelVivo 产品)
2026-07-28	2718e46d	feat(literature): Parate 2020 SCRT — PEMF 增强 MSC 旁分泌功能促软骨再生
2026-07-28	032de92f	feat: 精读 Lee 2025 Front Vet Sci 犬脂肪源 MSC 3D 球体

The 2026-08-16 cluster is a two-paper LDR cycle on the same day covering both an organ-on-chip microfluidic platform paper and an organoid ethical-review systematic-review paper:

• Quintard C et al. (2024) Nat Commun DOI 10.1038/s41467-024-45710-4 — a microfluidic platform for vascularized organoids-on-chip. The paper establishes: (i) 10-channel parallel microfluidic chip (COC 热压成型, U 型捕获位 300-800 µm 可调); (ii) fibrin + Matrigel hydrogel with Landau-Levich-Bretherton 效应 → 100% 捕获效率 in 10 sec per channel; (iii) hiPSC-derived blood vessel organoids (BVO, day 15)
  • GFP-HUVEC + 纤维细胞共培养 → 30 天功能性灌注培养; (iv) 壁剪切速率 27-2000 s⁻¹, mean 134-531 s⁻¹ (与人体毛细血管生理范围 50-1900 s⁻¹ 完美匹配); (v) 层级化血管: 37 µm 上游动脉-静脉 + 8 µm BVO 毛细管. The 4 commits are the same single file obsidian-vault/Literature/Deep-Reads/Organoid/quintard_2024_vasorganoid_chip.md walked through Robin's standard LDR cycle: (a) 0fc8db24 adds the file (189 lines, single-pass entry); (b) 290e9635 rewrites to -v2 修图床/双 H1/落款; (c) 24c713de adds -v3 Wiki.js 自带 图床 6 张图 (永久); (d) 4073abf4 is the -v4 转发语标题/落款 加粗 + 删 3Brain 工具名硬门槛合规修正. The "与我们的产品" table on the paper lists Mimetas OrganoPlate ⭐⭐⭐⭐ (直接对标: Phaseguide 微流控技术) + CelVivo ClinoStar ⭐⭐⭐ (类器官前段成熟期培养: BVO 在 hiPSC 分化到 day 15 需要悬浮旋转培养, ClinoStar 是该步骤 的金标准; day 15 后才转入芯片, ClinoStar 是完整工作流的前置) + Emulate Organ-Chip ⭐⭐⭐.
• Guo Z, Zhang N (2026) Front Cell Dev Biol DOI 10.3389/fcell.2026.1721946 — an IRB / ethical-review systematic-review paper for organoid biomedical research. The paper establishes: (i) 7 大强制要点 (样本来源合法性 / 捐赠者知情同意 [unlimited expansion / long-term cryopreservation / inter-lab sharing / cross-border / future unspecified research / commercial use / withdrawal mechanism] / 数据隐私与去标识化 / 共培养产物主体性评估 [Guo 2026 首次提出] / 动物福利 3R 原则 / 跨境监管合规 [中国 / 美国 / 欧盟 / 日本 / 韩国 对照表] / 长期保存与终止使用); (ii) 中国 IRB 实务视角 + 国际 ISSCR / GDPR / OHRP 双重参照 (作者团队 = 嘉兴市第一医院医学伦理 委员会 + 嘉兴大学医学院, 中国 IRB 实践者); (iii) 共培养产物 "新伦理实体" 框架 = 类器官 + 免疫细胞共培养 (CAR-T 培养) 不构成 "新生物体" 但构成 "新伦理实体", 需要独立审查. The 3 commits are the same single file obsidian-vault/Literature/Deep-Reads/Organoid/guo_2026_organoid_ethical_review.md walked through Robin's standard LDR cycle: (a) 2e6f5989 adds the file (170 lines, single-pass entry); (b) 00f824f2 -v2 修 图床 (加 2 张 Wiki.js 自带图); (c) a4fa5a32 -v3 补 Fig 1 (3 张图全) — Fig 1 is the "类器官共培养模型" 概念图 (Robin 8-16 实战反思: 综述类概念图通常较小, 提取阈值要从 0KB 起步全收, 再按 caption 关联; 之前 >200KB 过滤漏了 Fig 1). The "与我们的产品" table on the paper lists CelVivo ClinoStar ⭐⭐⭐⭐ (临床转化类 器官的伦理合规——本文 7 大要点直接适用于 ClinoStar 客户 IRB 申请; Robin 推广 ClinoStar 给三甲医院时, 可附带本框架作为增值) + Mimetas OrganoPlate ⭐⭐⭐⭐ (类器官共培养芯片的伦理审查依据—— Mimetas 主打"类器官 + 免疫细胞共培养", 本文主题 B 的共培养伦理 框架直接适用) + Emulate Organ-Chip ⭐⭐⭐ (类器官 + 微流控 芯片的跨境监管参考).

The 2026-08-12 cluster is a single-paper LDR cycle on Liang Y et al. (2026) Sci Rep DOI 10.1038/s41598-026-42990-2 — a mouse liver organoid platform paper from 澳门科技大学 + 香港大学 that establishes: (i) single-tissue 3-轨道 (Hep-Orgs + Cho-Orgs + HSC) separation; (ii) DAPT (Notch 抑制) + Dexamethasone for P1-P10 长程 稳定成熟 (ALB / PAS / LDL / CYP all stable across 10 passages — single DAPT only sustains P5); (iii) TGFβ 5-7 day activation of qHSC → aHSC (Acta2 / Col1a1 上调); (iv) aHSC 共培养诱导 Hep-Orgs EMT (Snail / Twist / Vimentin ↑; ALB / CK8 ↓; Lgr5 / EpCAM ↓; Ki67 ↓) = 体外肝纤维化模型. The 4 commits are the same single file 04-Literature/Deep-Reads/Liver/2026-08-12_Liang_2026_SciRep_liver_organoid_fibrosis_platform.md walked through Robin's standard 3-stage SOP cycle: (a) e542c977 adds the file (186 lines, single-pass entry); (b) 8699a154 rewrites the same file to the page 946 9 项 SOP 标杆 (105+/122- lines, adding the 6 核心发现 三段式 tables + 6 SeaFile Fig + "与我们的产品" 4-star table + 4-paper 参考文献 + 转发语 + 完整落款 + SeaFile PDF link); (c) aacba7aa + 297f106d are the page 934 修齐 micro-revisions (frontmatter title 改中文 / H1 去括号 / 元数据用 bold 单行 / 📄PDF 文件名 with actual filename) — the same alignment Robin applied across the 2026-08-11 OVB-类器官 cycle. The "与我们的产品" 4-star table on the paper lists CelVivo ClinoStar ⭐⭐⭐⭐ (P1-P10 长程扩增对应 旋转培养 30+ 天无剪切; HSC 静止态在模拟微重力下 7+ 天维持) + CelVivo ClinoReactor ⭐⭐⭐⭐ (单组织 3 轨道分通道灌流; TGFβ 时间程序 精确切换) + CelVivo PhaseHolographic 成像 ⭐⭐⭐ + 3Brain HD-MEA ⭐⭐⭐ (肝-神经互作延伸).

No new vault commits landed in the 2026-08-12T18:08Z → 2026-08-13T18:08Z window — the vault HEAD is unchanged at 297f106d. The 2026-08-12 Liang 2026 cluster remains the most recent committed vault activity. One new uncommitted file appeared in the working tree this fetch: 04-Literature/Deep-Reads/Review/zhou2023_computer_vision_microfluidics.md — the first entry in a new Review/ subfolder (see the Notable-entity section below).

7 new vault commits landed in the 2026-08-15T18:07Z → 2026-08-17T18:09Z window — the vault HEAD bumped from 297f106d to a4fa5a32. The two 2026-08-16 LDR cycles (Quintard 2024 microfluidic organ-on-chip + Guo 2026 organoid ethics systematic review) are the first time since the 2026-07-28 / 2026-07-29 Parate / Lee / Hodge cluster that two new paper deep-reads landed on main in the same 48-hour window. The 2026-08-16 cluster replaces the 2026-08-12 Liang 2026 cluster as the most recent committed vault activity. Two new untracked directories appeared in the working tree this fetch: celvivo_commercial/1331651_20260630_131201.pdf (the 6-30 quote PDF migrated into a new folder) + templates/类器官IRB申请清单.md (the IRB application checklist derived from Guo 2026 — Robin's first customer-facing sales ammunition template produced from a single deep-read; see the Notable-entity section below for synthesis).

The 2026-08-10 cluster is a frontmatter-hygiene + MOC-discipline sprint rather than new external evidence: (a) Phase A batch (d97b39ed) standardized 6 deep-read notes with the structured 6-field frontmatter (doi / journal / year / volume / pages / authors array / pmid) that the prior notes had been missing; (b) 方案 2 样品 (3b929c2f) added 7 image alt descriptions on top of the 6-field frontmatter for wang2024-org-on-chip.md; (c) MOC 方案 1 样品 (6b717aef) created Robin's first Map-of-Content file (04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md, 95 lines, 沙牛《AI 时代的 Obsidian 公开课》课时 1 pattern) and added related: back-link frontmatter to 7 papers. The MOC's own related: list already names the next planned MOC — [[MOC-3Brain-HD-MEA]] — plus [[02-Clients/Agents/_known_associations]] and [[02-Active-Deals/CellShot-TriArm-Demo-计划-v2-老师版-2026-07-20]], so the MOC pattern is expected to extend.

The 2026-08-08 cluster (prior manifest) was the literature flywheel-sync output (Liu 2026, Miao 2025 v2, Sharma 2026) — already indexed on /sources/literature.md. The 2026-08-07 / 2026-08-08 micro-revisions on Liu 2026 (a69ad9c4 → 1614ccf9) are the 8-step SOP rewrite cycle (v3 → v11) Robin re-ran on the same paper.

openwiki-wiki — working-tree status (2026-08-26)

• Branch: main
• HEAD: ebb95c0a85b85e5abb8d11463cfa8b855c504e5f (the chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-26) commit). The 2026-08-26T18:06Z fetch observed wiki HEAD bumped from 1003b92 (2026-08-25T18:13Z fetch) to ebb95c0a — 2 new automated wiki commits in the 2026-08-25T18:13Z → 2026-08-26T18:06Z 24-hour window: (a) 81ac94a chore: daily update 2026-08-26 (2026-08-26 02:23 +0800); (b) ebb95c0 chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-26, 2026-08-26 02:30 +0800). Both commits are routine auto-orchestration — the 81ac94a daily update carried the synthesis-layer edits from the prior HN-1 2026-08-25T18:00Z + HN-1 2026-08-26T18:00Z + web-search-1 2026-08-25 (skipped) + git-repo-1 2026-08-25T18:13Z runs; the ebb95c0 sources-sync re-applied the count-data wipe pattern on NocoDB / SeaFile / Wiki.js / RAGFlow for the twelfth consecutive time (after 997b648 2026-08-16 + be49285 2026-08-17 + 1fc73ae 2026-08-18
  • dcb53a2 2026-08-19 + bd30339 2026-08-20 + f6c2576 2026-08-21
  • 43d4548 2026-08-22 + 8f8f767 2026-08-23 + 127c2dc 2026-08-24
  • 1003b92 2026-08-25 + now ebb95c0 2026-08-26).
• Working-tree state: 8 modified files (uncommitted — pending next CLI orchestration). The 2026-08-26T18:06Z fetch observed the working tree at 8 uncommitted files (down from 11 at the 2026-08-25T18:13Z fetch because the 81ac94a 2026-08-26 daily update committed 14 of the prior 17 dirty files per git show --stat 81ac94a — including commitments.md + index.md + themes.md + themes/index.md + themes/05-robin-research.md + sources/git-repo.md + sources/hackernews.md + sources/index.md
  • sources/literature.md + sources/openwiki-version-drift.md + sources/web-search.md + sources/README.md + quickstart.md + .last-update.json — leaving 8 files re-modified by this git-repo-1 2026-08-26T18:06Z run). The 8 dirty files at this fetch are:
  • .last-update.json — CLI metadata, will be updated when this run's status: complete lands.
  • quickstart.md — contains the accumulated "Latest update" paragraphs from the prior HN-1 2026-08-25T18:00Z + HN-1 2026-08-26T18:00Z
    • web-search-1 2026-08-25 (skipped) + git-repo-1 2026-08-25T18:13Z runs + the "Latest update — git-repo-1 (2026-08-25T18:13Z)" paragraph added by the 2026-08-25 git-repo run; this git-repo-1 2026-08-26T18:06Z run adds the "Latest update — git-repo-1 (2026-08-26T18:06Z)" paragraph and updates the Backlog git-repo entry to reflect the new wiki HEAD ebb95c0a.
  • sources/README.md — refreshed connector-roll table row for web-search-1 + refreshed Active connectors Git repo row + HN row in this run.
  • sources/hackernews.md — accumulated "Latest update — 2026-08-25 18:00 UTC" + "Latest update — 2026-08-26 18:00 UTC" sections from the prior HN-1 runs (Qwen 3.8-Flash-Next ModelScope release announcement + Anthropic operational-distress + data-center water + GLM-5.3-Flash 530 pts release + Qwen3.8-Flash-Next actual release + Z.ai Ox Alpha Bloomberg confirmation + RAG Is Simpler Than You Think + Trail of Bits VMs-won't-contain-agents + Bill Gates turbulent-AI-era + LWN 3D-printer AGPL — adjacent, off-scope
    • the 15th + 16th consecutive empty / noise-only Algolia lane streak notes) — landed in uncommitted state during the HN-1 runs.
  • sources/nocodb.md — auto-generated count-table page that was re-touched by the ebb95c0 sources-sync 2026-08-26 commit (the twelfth consecutive count-data wipe re-application); the page body shows the count values from the prior 1003b92 sources-sync 2026-08-25 commit.
  • sources/ragflow.md — auto-generated count-table page that was re-touched by the ebb95c0 sources-sync 2026-08-26 commit (same pattern as sources/nocodb.md).
  • sources/seafile.md — auto-generated count-table page that was re-touched by the ebb95c0 sources-sync 2026-08-26 commit (same pattern as sources/nocodb.md).
  • sources/wikijs.md — auto-generated count-table page that was re-touched by the ebb95c0 sources-sync 2026-08-26 commit (same pattern as sources/nocodb.md).
• Auth: local path only — no remote, no credentials.
• New file in this window: none — the sources/openwiki-version-drift.md auto-generated page (created in the 2026-08-17 daily update 5c70881) was committed by the 81ac94a 2026-08-26 daily update; the file re-appears as dirty after this run because the very next synthesis edits re-touch the file (refresh of the timestamp) — same pattern as prior daily updates.
• Auth: local path only — no remote, no credentials.

Recent commits (latest first)

Date	Hash	Note
2026-08-26	ebb95c0	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-26) — count-data wipe re-applied for the twelfth consecutive sources-sync (after 2026-08-15 2507925 + 2026-08-16 997b648 + 2026-08-17 be49285 + 2026-08-18 1fc73ae + 2026-08-19 dcb53a2 + 2026-08-20 bd30339 + 2026-08-21 f6c2576 + 2026-08-22 43d4548 + 2026-08-23 8f8f767 + 2026-08-24 127c2dc + 2026-08-25 1003b92); see Notable-entity § "2026-08-15 sources-sync bug"
2026-08-26	81ac94a	chore: daily update 2026-08-26 (synthesis-layer edits accumulated from the prior HN-1 2026-08-25T18:00Z + HN-1 2026-08-26T18:00Z + web-search-1 2026-08-25 (skipped) + git-repo-1 2026-08-25T18:13Z runs; committed 14 of the prior 17 dirty files per git show --stat 81ac94a — including commitments.md + index.md + themes.md + themes/index.md + themes/05-robin-research.md + sources/git-repo.md + sources/hackernews.md + sources/index.md + sources/literature.md + sources/openwiki-version-drift.md + sources/web-search.md + sources/README.md + quickstart.md + .last-update.json; reducing uncommitted-file count from 11 → 8)
2026-08-25	1003b92	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-25) — count-data wipe re-applied for the eleventh consecutive sources-sync (after 2026-08-15 2507925 + 2026-08-16 997b648 + 2026-08-17 be49285 + 2026-08-18 1fc73ae + 2026-08-19 dcb53a2 + 2026-08-20 bd30339 + 2026-08-21 f6c2576 + 2026-08-22 43d4548 + 2026-08-23 8f8f767 + 2026-08-24 127c2dc); see Notable-entity § "2026-08-15 sources-sync bug"
2026-08-25	3255613	chore: daily update 2026-08-25 (synthesis-layer edits accumulated from the prior HN-1 2026-08-25T18:00Z + web-search-1 2026-08-25 (skipped) + git-repo-1 2026-08-25T18:13Z runs; committed 17 files from the prior dirty set per git show --stat 3255613 — including commitments.md + sources/git-repo.md + sources/hackernews.md + sources/index.md + sources/literature.md + sources/nocodb.md + sources/openwiki-version-drift.md + sources/ragflow.md + sources/seafile.md + sources/web-search.md + sources/wikijs.md + index.md + quickstart.md + sources/README.md + themes.md + themes/05-robin-research.md + themes/index.md; the very next synthesis edits from the git-repo-1 2026-08-25T18:13Z run re-touch the same files + add 2 newly dirty files per the manifest changedFiles list)
2026-08-24	127c2dc	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-24) — count-data wipe re-applied for the tenth consecutive sources-sync (after 2026-08-15 2507925 + 2026-08-16 997b648 + 2026-08-17 be49285 + 2026-08-18 1fc73ae + 2026-08-19 dcb53a2 + 2026-08-20 bd30339 + 2026-08-21 f6c2576 + 2026-08-22 43d4548 + 2026-08-23 8f8f767); see Notable-entity § "2026-08-15 sources-sync bug"
2026-08-23	a9568d8	chore: daily update 2026-08-23 (synthesis-layer edits accumulated from the prior HN-1 2026-08-22T18:00Z + web-search-1 2026-08-22 (skipped) + web-search-1 2026-08-23 (skipped) + git-repo-1 2026-08-22T18:13Z runs; committed sources/git-repo.md + sources/index.md + sources/nocodb.md + sources/ragflow.md + sources/seafile.md + sources/wikijs.md + themes/05-robin-research.md from the prior dirty set, reducing uncommitted-file count from 9 → 6)
2026-08-23	8f8f767	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-23) — count-data wipe re-applied for the ninth consecutive sources-sync (after 2026-08-15 2507925 + 2026-08-16 997b648 + 2026-08-17 be49285 + 2026-08-18 1fc73ae + 2026-08-19 dcb53a2 + 2026-08-20 bd30339 + 2026-08-21 f6c2576 + 2026-08-22 43d4548); see Notable-entity § "2026-08-15 sources-sync bug"
2026-08-22	43d4548	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-22) — count-data wipe re-applied for the eighth consecutive sources-sync (after 2026-08-15 2507925 + 2026-08-16 997b648 + 2026-08-17 be49285 + 2026-08-18 1fc73ae + 2026-08-19 dcb53a2 + 2026-08-20 bd30339 + 2026-08-21 f6c2576); see Notable-entity § "2026-08-15 sources-sync bug"
2026-08-22	d8e2277	chore: daily update 2026-08-22 (synthesis-layer edits accumulated from the prior HN-1 2026-08-22T18:00Z + web-search-1 2026-08-22 (skipped) + git-repo-1 2026-08-21T18:09Z runs)
2026-08-21	f6c2576	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-21) — count-data wipe re-applied for the seventh consecutive sources-sync (after 2026-08-15 2507925 + 2026-08-16 997b648 + 2026-08-17 be49285 + 2026-08-18 1fc73ae + 2026-08-19 dcb53a2 + 2026-08-20 bd30339); see Notable-entity § "2026-08-15 sources-sync bug"
2026-08-21	b6dc337	chore: daily update 2026-08-21 (synthesis-layer edits accumulated from the prior HN-1 2026-08-21T18:00Z + web-search-1 2026-08-21 (skipped) + git-repo-1 2026-08-20T18:09Z runs; committed sources/index.md from the 2026-08-20 dirty set)
2026-08-20	bd30339	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-20) — count-data wipe re-applied for the sixth consecutive sources-sync (after 2026-08-15 2507925 + 2026-08-16 997b648 + 2026-08-17 be49285 + 2026-08-18 1fc73ae + 2026-08-19 dcb53a2); see Notable-entity § "2026-08-15 sources-sync bug"
2026-08-20	a44f284	chore: daily update 2026-08-20 (synthesis-layer edits accumulated from the prior HN-1 2026-08-20T18:00Z + web-search-1 2026-08-20 (skipped) + git-repo-1 2026-08-19T18:08Z runs)
2026-08-19	dcb53a2	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-19) — count-data wipe re-applied for the fifth consecutive sources-sync (after 2026-08-15 2507925 + 2026-08-16 997b648 + 2026-08-17 be49285 + 2026-08-18 1fc73ae); see Notable-entity § "2026-08-15 sources-sync bug"
2026-08-19	7e904ec	chore: daily update 2026-08-19 (synthesis-layer edits accumulated from the prior HN-1 2026-08-19T18:00Z + web-search-1 2026-08-19 + git-repo-1 2026-08-18T18:10Z runs + the prior sources/openwiki-version-drift.md carryover)
2026-08-18	1fc73ae	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-18) — count-data wipe re-applied for the fourth consecutive sources-sync (after 2026-08-15 2507925 + 2026-08-16 997b648 + 2026-08-17 be49285); see Notable-entity § "2026-08-15 sources-sync bug"
2026-08-18	8127797	chore: daily update 2026-08-18 (synthesis-layer edits accumulated from the prior HN-1 2026-08-18T18:00Z + git-repo-1 2026-08-17T18:09Z runs + the new sources/openwiki-version-drift.md carryover)
2026-08-17	be49285	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-17)
2026-08-17	5c70881	chore: daily update 2026-08-17 (added sources/openwiki-version-drift.md auto-generated page + refreshed HN-1 / web-search-1 / git-repo-1 sections)
2026-08-16	997b648	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-16)
2026-08-16	151d22b	chore: daily update 2026-08-16 (committed sources/index.md from the 2026-08-15 dirty set; refreshed HN-1 / web-search-1 / git-repo-1 / themes/05-robin-research sections)
2026-08-15	2507925	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-15) — count-data wipe (NocoDB 6614 → 0, Wiki.js 83 → 0, RAGFlow landing 200 → 000); see Notable-entity § "2026-08-15 sources-sync bug"
2026-08-15	173b58c	chore: daily update 2026-08-15 (added OKF frontmatter to nocodb.md / ragflow.md / seafile.md / wikijs.md)
2026-08-14	6258717	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-14)
2026-08-14	021e929	chore: daily update 2026-08-14
2026-08-13	1737454	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-13)
2026-08-13	8ddc6d9	chore: daily update 2026-08-13 (commitment + quickstart + sources/literature + sources/web-search + themes/01-organoid-equipment + themes/05-robin-research from the HN-1 2026-08-13 synthesis pass)
2026-08-12	c57ead4	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-12)
2026-08-12	431ee6a	chore: daily update 2026-08-12
2026-08-11	b64ae41	lit: PMID 41536916 Bioactive Materials AIVOs 综述 (Wiki.js 1711)
2026-08-11	523ee7f	lit: PMID 41686639 Cell Reports TNBC DEO + ROCK (Wiki.js 1710)
2026-08-11	9be4f55	lit: PMID 41909700 Front Immunol 2026 类器官-小胶质细胞综述 (Wiki.js 1709)
2026-08-11	cc69ece	lit: PMID 42041571 v4 - 按 literature-deep-read-research 9 项强制格式
2026-08-11	b4bc8d9	lit: PMID 42041571 修正 - 真实PDF + 10张真图链接
2026-08-11	12480ab	lit: 修正 wiki_url 到真实内网地址
2026-08-11	cdc59c5	lit: PMID 42041571 OVB-organoids vs cerebral organoids Cells 2026
2026-08-11	2bcde39	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-11)
2026-08-11	7556e31	chore: daily update 2026-08-11
2026-08-09	dde053a	auto: 2026-08-09 Wang 2024 Theranostics OrgOC 综述精读入口
2026-08-09	3267338	chore: daily update 2026-08-09
2026-08-09	06f60e1	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-09)
2026-08-08	c94940c7	feat: add Microbioreactor 2026 v4 (PMID 42516424, ID 1696)
2026-08-08	7f65024	feat: add Microbioreactor 2026 v3 (PMID 42516424)
2026-08-08	ea4f14a	feat: add Microbioreactor 2026 v2 (PMID 42516424)
2026-08-08	a193e46	feat: add Microbioreactor 2026 (PMID 42516424) deep-read entry
2026-08-08	bf90a91	fix: liu 2026 wiki link to main path
2026-08-08	cf1dbe0	fix: liu 2026 final link
2026-08-08	26efd2f	fix: liu 2026 v5 link
2026-08-08	e18993a	fix: liu 2026 v4 link
2026-08-08	b206bd9	fix: liu 2026 v3 link
2026-08-08	c26dbdf	fix: liu 2026 wiki link to v2
2026-08-08	703c3d4	literature: liu 2026 NBME shape-conformal organoid
2026-08-08	1b78735	literature: miao 2025 cell v2
2026-08-08	5adc406	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-08)
2026-08-08	037c5f3	lit: add Sharma K 2026 Cell Stem Cell vRO retinal organoid (PMID 41529691)
2026-08-07	9e80977	feat(openwiki): complete data flywheel activation (2026-08-07)
2026-08-07	45af5a4	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-07)
2026-08-07	bcd4a4f	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-07)
2026-08-07	0bbef0f	feat(openwiki v0.3.1 --update): generate themes 4-5 + index.md + themes/ + sources/ index (2026-08-07)
2026-08-07	285c53b	feat(openwiki v0.3.1): add YAML frontmatter + install-id markers from initial init run (2026-08-07)
2026-07-24	3102e96	feat(sources): 全国 261 家经销商地图 (2026-07-24, 不含敏感信息)

The wiki repo is the OpenWiki output itself — it persists across update runs. 4 new wiki-side commits landed in the 2026-08-13T18:08Z → 2026-08-15T18:07Z window: (a) 021e929 (2026-08-14 +0800 02:18, chore: daily update 2026-08-14); (b) 6258717 (2026-08-14 +0800 02:30, chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-14)); (c) 173b58c (2026-08-15 +0800 02:00, chore: daily update 2026-08-15 — added OKF frontmatter to nocodb.md / ragflow.md / seafile.md / wikijs.md); (d) 2507925 (2026-08-15 +0800 02:31, chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-15) — count-data wipe carried into the source pages; see Notable-entity § "2026-08-15 sources-sync bug" below). Between these 4 commits, the wiki HEAD advanced from 1737454 (2026-08-13 sources-sync) to 2507925 (2026-08-15 sources-sync). The 6 wiki commits from 2026-08-11 / 2026-08-12 (7556e31 / 431ee6a daily + 2bcde39 / c57ead4 sources-sync + the 6 lit-PMID commits on 2026-08-11 + 2bc03f3 / 06f60e1 / 5adc406 / 3267338 / dde053a from the 2026-08-08 / 2026-08-09 cluster) are all already in 2507925's ancestry. The Liang 2026 wiki sync has not yet landed (the /sources/literature.md short row is in working tree only); the next wiki commit should add a fuller Liang 2026 row when the synthesis pipeline catches up.

Summary of last 48 hours

Window (UTC)	Vault	Wiki
2026-08-25T18:13:00Z → 2026-08-26T18:06:00Z	HEAD unchanged at 9d4767c7 (0 new commits, 0 new mtime changes — vault silent for the 1st consecutive fetch since the 2026-08-24/25 SECOND 5-paper burst; the 2026-08-25 5-paper cluster remains the most recent vault activity, 1 calendar day stale; the carry-forward untracked-file set bumps: Review/zhou2023_computer_vision_microfluidics.md 14-day → 15-day carry-forward (12 → 13 fetches silent) + celvivo_commercial/ + templates/ 9-day → 10-day carry-forward + deepread_40240593/ 2-day → 3-day carry-forward; no new untracked dirs)	HEAD 1003b92 → ebb95c0a (2 new automated commits: 81ac94a chore: daily update 2026-08-26 (2026-08-26T02:23 +0800, committed 14 of the prior 17 dirty files per git show --stat 81ac94a — including commitments.md + index.md + themes.md + themes/index.md + themes/05-robin-research.md + sources/git-repo.md + sources/hackernews.md + sources/index.md + sources/literature.md + sources/openwiki-version-drift.md + sources/web-search.md + sources/README.md + quickstart.md + .last-update.json; reducing uncommitted-file count from 11 → 8) + ebb95c0 chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-26, 2026-08-26T02:30 +0800, the twelfth consecutive sources-sync re-applying the 2507925 2026-08-15 count-data wipe pattern after 997b648 2026-08-16 + be49285 2026-08-17 + 1fc73ae 2026-08-18 + dcb53a2 2026-08-19 + bd30339 2026-08-20 + f6c2576 2026-08-21 + 43d4548 2026-08-22 + 8f8f767 2026-08-23 + 127c2dc 2026-08-24 + 1003b92 2026-08-25 + now ebb95c0 2026-08-26); the manifest changedFiles shows 8 dirty wiki files this fetch — M .last-update.json + M quickstart.md + M sources/README.md + M sources/hackernews.md + M sources/nocodb.md + M sources/ragflow.md + M sources/seafile.md + M sources/wikijs.md)
---	---	---
2026-08-24T18:05:00Z → 2026-08-25T18:13:00Z	HEAD fb017e4f → 9d4767c7 (5 new commits: 089177a7 Tevonian 2026 Nat Commun 血管化肝 MPS + 583859a8 Yang 2026 Stem Cell Res Ther cardiac organoid review + 9aa2af4c Tevonian + Yang product-mapping retrofit + 5907cdfc Shen 2026 Chin Med J vascularized organoids review + 9d4767c7 Zhai 2026 Sci Adv 3D skin pemphigus — SECOND consecutive single-day 5-paper LDR burst; combined with the 2026-08-23/24 5-paper burst, 10 LDR papers in 48 hours = largest sustained 2-day research output in Robin's vault activity log; the cluster creates 3 new 04-Literature/Deep-Reads/ subfolders: Vascularized-Organoids/ (Tevonian + Shen) + Cardiac-Organoids/ (Yang) + Skin-Organoids/ (Zhai), expanding Robin's per-vendor / per-application-domain subfolder taxonomy from ~19 to ~22; the cluster includes the first post-publish vendor-mapping retrofit commit (9aa2af4c) — adding CelVivo/Cellink/Mimetas/3Brain/Femtobiomed product mapping + 净化 Robin mentions to Tevonian + Yang retroactively)	HEAD 127c2dc → 1003b92 (2 new automated commits: 3255613 chore: daily update 2026-08-25 + 1003b92 chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-25, the eleventh consecutive sources-sync re-applying the 2507925 2026-08-15 count-data wipe pattern after 997b648 2026-08-16 + be49285 2026-08-17 + 1fc73ae 2026-08-18 + dcb53a2 2026-08-19 + bd30339 2026-08-20 + f6c2576 2026-08-21 + 43d4548 2026-08-22 + 8f8f767 2026-08-23 + 127c2dc 2026-08-24 + now 1003b92 2026-08-25); the 3255613 daily update committed 17 files per git show --stat 3255613 (including commitments.md + sources/git-repo.md + sources/hackernews.md + sources/index.md + sources/literature.md + sources/nocodb.md + sources/openwiki-version-drift.md + sources/ragflow.md + sources/seafile.md + sources/web-search.md + sources/wikijs.md + index.md + quickstart.md + sources/README.md + themes.md + themes/05-robin-research.md + themes/index.md); the manifest changedFiles shows 11 dirty wiki files this fetch — M .last-update.json + M index.md + M quickstart.md + M sources/README.md + M sources/git-repo.md + M sources/hackernews.md + M sources/literature.md + M sources/nocodb.md + M sources/ragflow.md + M sources/seafile.md + M sources/web-search.md + M sources/wikijs.md)
2026-08-23T18:11:00Z → 2026-08-24T18:05:00Z	HEAD a4fa5a32 → fb017e4f (5 new commits: ad4abcde Ajongbolo 2025 Cells brain organoid review + 5f02489a Kim 2025 Nat Commun EGaIn 3D MEA + 40b357b8 Tian 2025 Nat Commun hiPSC epicardium mTOR + f2118a62 Aiello & Bagni 2025 biorxiv Rotating Chamber brain organoid CFD + fb017e4f CelVivo App Note 2026 ClinoStar vs orbital shaker head-to-head — largest single-day LDR burst since the 2026-07-29 Parate / Lee / Hodge cluster, breaks the 7-fetch vault silence streak that started after the 2026-08-16 Quintard + Guo cluster; all 5 are single-shot entries at obsidian-vault/04-Literature/Deep-Reads/ root (no v2/v3 SOP rewrite cycles this cluster); commit timestamps 07:50 → 16:39 +0800 across the 2026-08-24 day)	HEAD a9568d8 → 127c2dc (2 new automated commits: 9cc5e63 chore: daily update 2026-08-24 + 127c2dc chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-24, the tenth consecutive sources-sync re-applying the 2507925 2026-08-15 count-data wipe pattern after 997b648 2026-08-16 + be49285 2026-08-17 + 1fc73ae 2026-08-18 + dcb53a2 2026-08-19 + bd30339 2026-08-20 + f6c2576 2026-08-21 + 43d4548 2026-08-22 + 8f8f767 2026-08-23 + now 127c2dc 2026-08-24) + the prior a9568d8 2026-08-23 daily update was committed in this fetch's prior daily update cycle before the 5-paper burst landed; 9cc5e63 committed sources/git-repo.md + sources/hackernews.md + sources/index.md + sources/openwiki-version-drift.md + sources/web-search.md + themes/05-robin-research.md from the prior dirty set; the manifest changedFiles shows 8 dirty files this fetch — M .last-update.json + M sources/hackernews.md + M sources/literature.md + M sources/nocodb.md + M sources/ragflow.md + M sources/seafile.md + M sources/web-search.md + M sources/wikijs.md)
2026-08-15T18:07:49Z → 2026-08-17T18:09:32Z	HEAD 297f106d → a4fa5a32 (7 new commits: 0fc8db24 + 290e9635 + 24c713de + 4073abf4 Quintard 2024 Nat Commun microfluidic vascularized organoid chip 4-commit LDR cycle + 2e6f5989 + 00f824f2 + a4fa5a32 Guo 2026 Front Cell Dev Biol organoid ethics systematic review 3-commit LDR cycle — first time since the 2026-07-28 / 2026-07-29 Parate / Lee / Hodge cluster that two new paper deep-reads landed on main in the same 48-hour window)	HEAD 2507925 → be49285 (4 new commits: 151d22b daily update 2026-08-16 + 997b648 sources-sync 2026-08-16 + 5c70881 daily update 2026-08-17 + be49285 sources-sync 2026-08-17)
2026-08-17T18:09:32Z → 2026-08-18T18:10:12Z	HEAD unchanged at a4fa5a32 (0 new commits, 0 new mtime changes — vault is silent in this 24-hour window; the 2026-08-16 Quintard 2024 + Guo 2026 cluster remains the most recent vault activity)	HEAD be49285 → 1fc73ae (2 new automated commits: 8127797 chore: daily update 2026-08-18 + 1fc73ae chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-18, the fourth consecutive sources-sync re-applying the 2507925 2026-08-15 count-data wipe pattern))
2026-08-19T18:08:24Z → 2026-08-20T18:09:15Z	HEAD unchanged at a4fa5a32 (0 new commits, 0 new mtime changes — vault is silent in this 24-hour window for the 4th consecutive fetch; the 2026-08-16 Quintard 2024 + Guo 2026 cluster remains the most recent vault activity, 4 calendar days stale)	HEAD dcb53a2 → bd30339 (2 new automated commits: a44f284 chore: daily update 2026-08-20 + bd30339 chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-20, the sixth consecutive sources-sync re-applying the 2507925 2026-08-15 count-data wipe pattern after 997b648 2026-08-16 + be49285 2026-08-17 + 1fc73ae 2026-08-18 + dcb53a2 2026-08-19 + now bd30339 2026-08-20))
2026-08-18T18:10:12Z → 2026-08-19T18:08:24Z	HEAD unchanged at a4fa5a32 (0 new commits, 0 new mtime changes — vault is silent in this 24-hour window for the 3rd consecutive fetch; the 2026-08-16 Quintard 2024 + Guo 2026 cluster remains the most recent vault activity, 3 calendar days stale)	HEAD 1fc73ae → dcb53a2 (2 new automated commits: 7e904ec chore: daily update 2026-08-19 + dcb53a2 chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-19, the fifth consecutive sources-sync re-applying the 2507925 2026-08-15 count-data wipe pattern after 997b648 2026-08-16 + be49285 2026-08-17 + 1fc73ae 2026-08-18 + now dcb53a2 2026-08-19))
2026-08-20T18:09:15Z → 2026-08-21T18:09:00Z	HEAD unchanged at a4fa5a32 (0 new commits, 0 new mtime changes — vault is silent in this 24-hour window for the 5th consecutive fetch; the 2026-08-16 Quintard 2024 + Guo 2026 cluster remains the most recent vault activity, 5 calendar days stale)	HEAD bd30339 → f6c2576 (2 new automated commits: b6dc337 chore: daily update 2026-08-21 + f6c2576 chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-21, the seventh consecutive sources-sync re-applying the 2507925 2026-08-15 count-data wipe pattern after 997b648 2026-08-16 + be49285 2026-08-17 + 1fc73ae 2026-08-18 + dcb53a2 2026-08-19 + bd30339 2026-08-20 + now f6c2576 2026-08-21))
2026-08-21T18:09:00Z → 2026-08-22T18:13:00Z	HEAD unchanged at a4fa5a32 (0 new commits, 0 new mtime changes — vault is silent in this 24-hour window for the 6th consecutive fetch; the 2026-08-16 Quintard 2024 + Guo 2026 cluster remains the most recent vault activity, 6 calendar days stale)	HEAD f6c2576 → 43d4548 (2 new automated commits: d8e2277 chore: daily update 2026-08-22 + 43d4548 chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-22, the eighth consecutive sources-sync re-applying the 2507925 2026-08-15 count-data wipe pattern after 997b648 2026-08-16 + be49285 2026-08-17 + 1fc73ae 2026-08-18 + dcb53a2 2026-08-19 + bd30339 2026-08-20 + f6c2576 2026-08-21 + now 43d4548 2026-08-22))
2026-08-22T18:13:00Z → 2026-08-23T18:11:00Z	HEAD unchanged at a4fa5a32 (0 new commits, 0 new mtime changes — vault is silent in this 24-hour window for the 7th consecutive fetch; the 2026-08-16 Quintard 2024 + Guo 2026 cluster remains the most recent vault activity, 7 calendar days stale)	HEAD 43d4548 → a9568d8 (2 new automated commits: 8f8f767 chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-23, the ninth consecutive sources-sync re-applying the 2507925 2026-08-15 count-data wipe pattern after 997b648 2026-08-16 + be49285 2026-08-17 + 1fc73ae 2026-08-18 + dcb53a2 2026-08-19 + bd30339 2026-08-20 + f6c2576 2026-08-21 + 43d4548 2026-08-22 + now 8f8f767 2026-08-23) + a9568d8 chore: daily update 2026-08-23 (carried the synthesis-layer edits from the prior HN-1 2026-08-22T18:00Z + web-search-1 2026-08-22 (skipped) + web-search-1 2026-08-23 (skipped) + git-repo-1 2026-08-22T18:13Z runs; committed 7 of the prior 9 dirty files — sources/git-repo.md + sources/index.md + sources/nocodb.md + sources/ragflow.md + sources/seafile.md + sources/wikijs.md + themes/05-robin-research.md — reducing uncommitted-file count from 9 → 6; the very next synthesis edits from this git-repo-1 2026-08-23T18:11Z run re-touch the remaining 6 files + 1 newly dirty sources/openwiki-version-drift.md))
Net new external evidence	2 new paper deep-reads (from the 2026-08-15T18:07Z → 2026-08-17T18:09Z window): Quintard 2024 Nat Commun microfluidic vascularized organoid chip + Guo 2026 Front Cell Dev Biol organoid ethics systematic review. 2 new untracked directories (from the same window): celvivo_commercial/1331651_20260630_131201.pdf (the 6-30 quote PDF migrated into a new folder) + templates/类器官IRB申请清单.md (the IRB application checklist derived from Guo 2026 — Robin's first customer-facing sales ammunition template produced from a single deep-read). The Review/zhou2023_computer_vision_microfluidics.md first-entry-in-Review/-subfolder is still untracked, carrying forward from the 2026-08-13 fetch (11-day carry-forward at the 2026-08-22T18:13Z fetch — was 10-day at the 2026-08-21T18:09Z fetch — was 9-day at the 2026-08-20T18:09Z fetch). No new vault evidence in the 2026-08-21T18:09Z → 2026-08-22T18:13Z 24-hour window	1 new wiki file (from the 2026-08-17 daily update 5c70881): sources/openwiki-version-drift.md (auto-generated OpenWiki version-drift monitor; v0.3.1 local → v0.3.3 npm latest as of 2026-08-15T20:00:03Z). Wiki-side: the 2026-08-22T18:13Z fetch observed wiki HEAD bump f6c2576 → 43d4548 — 2 new automated wiki commits (d8e2277 daily update 2026-08-22 + 43d4548 sources-sync 2026-08-22 — the eighth consecutive sources-sync re-applying the 2507925 2026-08-15 count-data wipe pattern). Synthesis-layer edits accumulated across the prior HN-1 2026-08-13 + HN-1 2026-08-15 + HN-1 2026-08-16 + HN-1 2026-08-17 + HN-1 2026-08-18 + HN-1 2026-08-19 + HN-1 2026-08-20 + HN-1 2026-08-21 + HN-1 2026-08-22 + web-search-1 2026-08-15 + web-search-1 2026-08-17 + web-search-1 2026-08-18 + web-search-1 2026-08-19 + web-search-1 2026-08-20 (skipped) + web-search-1 2026-08-21 (skipped) + web-search-1 2026-08-22 (skipped) + git-repo-1 2026-08-13 + git-repo-1 2026-08-15 + git-repo-1 2026-08-17 + git-repo-1 2026-08-18 + git-repo-1 2026-08-19 + git-repo-1 2026-08-20 + git-repo-1 2026-08-21 + this git-repo-1 2026-08-22 runs are pending the next CLI commit cycle
Untracked → committed migrations	Quintard 2024 file (4 commits) + Guo 2026 file (3 commits) all moved from absent → committed on main (in the 2026-08-15T18:07Z → 2026-08-17T18:09Z window); the 2 new untracked directories are net-new in the same window. None in the 2026-08-17T18:09Z → 2026-08-18T18:10Z 24-hour window (vault silent) or the 2026-08-18T18:10Z → 2026-08-19T18:08Z 24-hour window (vault silent for the 3rd consecutive fetch) or the 2026-08-19T18:08Z → 2026-08-20T18:09Z 24-hour window (vault silent for the 4th consecutive fetch) or the 2026-08-20T18:09Z → 2026-08-21T18:09Z 24-hour window (vault silent for the 5th consecutive fetch) or the 2026-08-21T18:09Z → 2026-08-22T18:13Z 24-hour window (vault silent for the 6th consecutive fetch).	2026-08-15T18:07Z → 2026-08-17T18:09Z window: the sources/index.md from the 2026-08-15 dirty set was committed by the 2026-08-16 daily update 151d22b; the remaining 9 dirty files are uncommitted synthesis edits accumulated across the prior HN-1 + web-search-1 + git-repo-1 runs. 2026-08-17T18:09Z → 2026-08-18T18:10Z window: the 8127797 2026-08-18 daily update committed a subset of the synthesis-layer edits from the prior HN-1 2026-08-18T18:00Z + git-repo-1 2026-08-17T18:09Z runs (touching commitments.md + index.md + quickstart.md + sources/{README,git-repo,hackernews,index,literature,nocodb,ragflow,seafile,web-search,wikijs}.md + themes/{01-organoid-equipment,05-robin-research}.md per git show --stat 8127797); the 9 dirty files re-appear in the working tree because the very next synthesis edits from this git-repo-1 2026-08-18T18:10Z run re-touch the same files. 2026-08-18T18:10Z → 2026-08-19T18:08Z window: the 7e904ec 2026-08-19 daily update committed a subset of the synthesis-layer edits from the prior HN-1 2026-08-19T18:00Z + web-search-1 2026-08-19 + git-repo-1 2026-08-18T18:10Z runs (touching .last-update.json + quickstart.md + sources/{README,git-repo,hackernews,index,nocodb,ragflow,seafile,web-search,wikijs}.md + themes/05-robin-research.md per git show --stat 7e904ec); the 10 dirty files (.last-update.json + quickstart.md + sources/{README,hackernews,index,nocodb,ragflow,seafile,web-search,wikijs}.md) re-appear in the working tree because the very next synthesis edits from this git-repo-1 2026-08-19T18:08Z run re-touch the same files. 2026-08-19T18:08Z → 2026-08-20T18:09Z window: the a44f284 2026-08-20 daily update committed a subset of the synthesis-layer edits from the prior HN-1 2026-08-20T18:00Z + web-search-1 2026-08-20 (skipped) + git-repo-1 2026-08-19T18:08Z runs; the 10 dirty files re-appear in the working tree because the very next synthesis edits from this git-repo-1 2026-08-20T18:09Z run re-touch the same files. 2026-08-20T18:09Z → 2026-08-21T18:09Z window: the b6dc337 2026-08-21 daily update committed a subset of the synthesis-layer edits from the prior HN-1 2026-08-21T18:00Z + web-search-1 2026-08-21 (skipped) + git-repo-1 2026-08-20T18:09Z runs; sources/index.md was committed by b6dc337 (was re-appearing as dirty since 2026-08-16 daily update). The 9 dirty files (.last-update.json + quickstart.md + sources/{README,hackernews,nocodb,ragflow,seafile,web-search,wikijs}.md) re-appear in the working tree because the very next synthesis edits from this git-repo-1 2026-08-21T18:09Z run re-touch the same files. 2026-08-21T18:09Z → 2026-08-22T18:13Z window: the d8e2277 2026-08-22 daily update committed a subset of the synthesis-layer edits from the prior HN-1 2026-08-22T18:00Z + web-search-1 2026-08-22 (skipped) + git-repo-1 2026-08-21T18:09Z runs; the 9 dirty files (.last-update.json + quickstart.md + sources/{README,hackernews,nocodb,ragflow,seafile,web-search,wikijs}.md) re-appear in the working tree because the very next synthesis edits from this git-repo-1 2026-08-22T18:13Z run re-touch the same files. The 9 dirty files are awaiting the next CLI commit cycle
Operational issue carried over from prior runs	n/a	2507925 2026-08-15 sources-sync bug + the 2026-08-16 997b648 + 2026-08-17 be49285 + 2026-08-18 1fc73ae + 2026-08-19 dcb53a2 + 2026-08-20 bd30339 + 2026-08-21 f6c2576 + 2026-08-22 43d4548 sources-syncs (which re-applied the same operational pattern as 2507925 — NocoDB / Wiki.js / RAGFlow count values stayed zero across all 8 sources-syncs). The on-disk ~/.openwiki/connectors/web-search/config.json is unaffected — this is a wiki-side CRON issue with the auto-source-sync job, not a connector config issue. Recorded for traceability on /sources/git-repo.md Notable-entity § "2026-08-15 sources-sync bug" and on each affected /sources/{nocodb,ragflow,seafile,wikijs}.md page. The data is recoverable from git show 8ddc6d9:sources/nocodb.md etc. for any future recovery commit

Vault navigation index

The vault uses a numbered top-level layout. Scripts, caches, and temp* working folders are excluded from this index.

Dir	Purpose	Size hint
01-Active-Sales/	Active sales pipeline files (board + per-account)	6 .md
02-Active-Deals/	Deal-level active docs	1 .md
02-Clients/, 02-Contacts/	Client & contact records	sparse
03-Product/	Product briefs (e.g. 3Brain-Maxwell comparison)	1 .md
03-Resources/Agents/	Distributor / agent profiles	a handful
03-Resources/End-Customers/	End-customer dossiers (3Brain MEA accounts, etc.)	11+ .md
03-Resources/ITX-24h-Host/	Personal 24h Hermes-Agent / AI-workflow host build config (2026-07-31 untracked; not yet on main)	1 .md
04-Literature/	Paper deep-reads + curated vendor PDFs	see breakdown
05-Documents/Contracts/	Signed/pending contracts (Celvivo subfolder)	—
05-Documents/Products/	Vendor-facing product docs (Celvivo/Industrial-Customers)	—
05-Documents/{Proposals,Quotes,Visit-Plans}/	Active commercial docs	—
05-Products/	In-house product briefs (MappingLab family)	2 .md
06-Sales/Competitors/	Competitor tracking	—
06-Sales/Configurations/	Product configurations	—
06-Sales/Content/{FAQ,Pain-Points,PPT-Scripts,Success-Stories,Training-Materials,推文模板}/	Sales content library	—
06-Sales/{Price-List,Product-Mapping,Recommendation-Engine}/	Sales tooling	—
99-Templates/	Reusable Obsidian templates	14 .md
memory/	Daily reports, weekly digests, .dreams, archive	147 .md

04-Literature/Deep-Reads/ breakdown

Markdown file counts per deep-read subfolder:

Subfolder	.md count
Organoid/	661 (+2 from 2026-08-16 — Quintard 2024 Nat Commun microfluidic vascularized organoid chip + Guo 2026 Front Cell Dev Biol organoid ethics systematic review)
04-Literature/Deep-Reads/ root	+5 new files on 2026-08-23 single-shot LDR burst — CelVivo_Shear_Stress_AppNote_2026 + Aiello_Bagni_2025_biorxiv_Brain_Organoid_Fluid + Tian_2025_NatCommun_Epicardium_mTOR + Kim_2025_NatCommun_Liquid_Metal_3D_MEA + Ajongbolo_2025_Cells_Brain_Organoids_Review (all in vault root, not in a per-vendor subfolder — this is a non-standard pattern vs the prior per-vendor subfolder discipline, see Notable-entity § "2026-08-23 root-level LDR burst")
Celvivo/	142
3Brain/	136
Cellink/	129
Organoid-List/	51
Product-Reports/	38
Brain/	11
Brain-Tumor/	9
Cancer/	6
Liver/	6
Other/	6
RegenMed/	1
3Brain MEA/	3
Cardiac/	2
Kidney/	2
Retinal/	1
Microbioreactor/	1 (new as of 2026-08-07 — Rosero 2026 Front Bioeng Biotechnol)
Cells/	1 (new as of 2026-08-08 — Fernandez Vallone 2026 Cells THSDC)
Review/	1 (new as of 2026-08-13 — Zhou 2023 computer vision + microfluidics, untracked, 10-day carry-forward at 2026-08-21 fetch, 8 fetches silent — structural signal continuing to weaken; 11-day carry-forward at 2026-08-22 fetch, 9 fetches silent; 12-day carry-forward at 2026-08-23 fetch, 10 fetches silent; 13-day carry-forward at 2026-08-24 fetch, 11 fetches silent — structural signal continues to weaken; 14-day carry-forward at 2026-08-25 fetch, 12 fetches silent — structural signal continues to weaken, subfolder is more likely one-off than recurring; 15-day carry-forward at 2026-08-26 fetch, 13 fetches silent — structural signal continues to weaken, subfolder is more likely one-off than recurring)
templates/	1 (new as of 2026-08-17 — 类器官IRB申请清单.md, derived from the Guo 2026 ethics deep-read; Robin's first customer-facing template produced from a single deep-read, untracked, 5-day carry-forward at 2026-08-21 fetch (was 4-day at 2026-08-20); 6-day carry-forward at 2026-08-22 fetch; 7-day carry-forward at 2026-08-23 fetch; 8-day carry-forward at 2026-08-24 fetch; 9-day carry-forward at 2026-08-25 fetch; 10-day carry-forward at 2026-08-26 fetch)
celvivo_commercial/	1 (new as of 2026-08-17 — 1331651_20260630_131201.pdf, the 6-30 quote PDF migrated into a new folder, untracked, 5-day carry-forward at 2026-08-21 fetch (was 4-day at 2026-08-20); 6-day carry-forward at 2026-08-22 fetch; 7-day carry-forward at 2026-08-23 fetch; 8-day carry-forward at 2026-08-24 fetch; 9-day carry-forward at 2026-08-25 fetch; 10-day carry-forward at 2026-08-26 fetch)
Vascularized-Organoids/	2 (new as of 2026-08-25 — Tevonian_2026_Nat_Commun_Vascularized_Liver_MPS.md + Shen_2026_Chin_Med_J_Vascularized_Organoids_Review.md; the prior per-vendor subfolder discipline returns after the 2026-08-23/24 root-level burst; subfolder semantics: vascularized organoid application-domain cluster)
Cardiac-Organoids/	1 (new as of 2026-08-25 — Yang_2026_Stem_Cell_Res_Ther_Cardiac_Organoid_Review.md; expanded from the prior 2-file Cardiac/ subfolder into a dedicated Cardiac-Organoids subfolder — companion application-domain to the existing 2-paper Cardiac bucket)
Skin-Organoids/	1 (new as of 2026-08-25 — Zhai_2026_Sci_Adv_3D_Skin_Pemphigus.md; net-new application domain (autoimmune dermatology + 3D skin) to Robin's deep-read set; companion to the existing Cardiac / Brain / Liver / Vascularized-Organoids / Cancer / Kidney / Retinal application-domain subfolders)

Total ≈ 1,217 deep-read notes on main (+4 new LDR files from the 2026-08-24/25 cluster on top of +5 from the 2026-08-23/24 single-shot LDR burst and +2 from the 2026-08-16 Quintard 2024 + Guo 2026 clusters; the 5th 2026-08-25 commit 9aa2af4c is an in-place M touch on Tevonian + Yang files, not a new file). Robin's LDR cluster pattern is now 2 consecutive 5-commit windows (2026-08-23/24 + 2026-08-24/25), totalling 11 commits / 9 new files in 48 hours. Review/ zhou2023 computer vision + microfluidics, untracked — only counts once committed; +2 working-tree files in the new templates/ + celvivo_commercial/ directories, both untracked; +1 working-tree directory deepread_40240593/ (7 subdirs, 2026-08-24) carrying pipeline intermediate artifacts from the 5-paper burst). The 2026-08-23/24 single-shot LDR burst (5 papers at vault root) is the most recent committed deep-read cluster; the 2026-08-16 Quintard 2024 + Guo 2026 cluster remains the prior committed cluster; the 2026-08-07 / 2026-08-08 cluster (Microbioreactor + Cells) remains the prior-prior committed cluster. CelVivo, 3Brain, Cellink, and the broad Organoid/ bucket cover Robin's product KB per the wiki goal focus areas (类器官培养与设备, 3D 生物打印). The new templates/ folder signals Robin may be formalizing customer-facing deliverables (checklists / templates / sales scripts) as a separate vault subtree — the IRB application checklist is the first such artifact.

Distributor map refresh (2026-08-07)

Robin uploaded a refreshed b7f52af896c1e3a9.xlsx on 2026-08-07 11:11, producing 8 new *2026-0807.md regional files + a new 全国经销商地图-2026-0807.md index + a new product-association index (_known_associations.md) + a new _meta.json reflecting the 259-dealer tally. The 2026-07-24 baseline (*2026-0724.md × 7 + index) remains in the repo but is now stale.

What changed in the 2026-08-07 baseline vs the 2026-07-24 baseline:

Dimension	2026-07-24 (_meta.json)	2026-08-07 (全国经销商地图-2026-0807.md)
Total dealers	261 (明细表口径)	259 (公司数量汇总)
xlsx sha256	3afd448edcf3a9673848da0de2c554e6a4b22d7329b988695ca242c8bc8c10cf	(re-uploaded with 8-04 同名 + 新增 2-3 家)
Region table	华北 74 / 华东 68 / 华南 62 / 山东 25 / 湖北 19 / 西北 6 / 西南 7	华北 72 / 华东 68 / 华南 62 / 山东 25 / 湖北 19 / 西北 6 / 西南 7
华北 count	74	72 (-2)
Hook 4 output	(none)	4 dealer-management hooks + _known_associations.md

The numeric 261 vs 259 difference is still rooted in the 华北 表 74 vs 汇总 72 discrepancy (two unnamed companies — 序号 63 / 67 — leave the 明细表 2 rows above the 汇总表); the 2026-08-07 baseline carries the same data anomaly plus a new structural artifact: 济南成全生物科技 (曹沛起) is registered in both 华北-2026-0807.md and 山东-2026-0807.md (legitimate cross-region duplicate) — this is the only CelVivo ClinoStar agent in the 259-dealer list and is the thread Robin should follow to close the agent-dong-huiqun-celvivo open question.

_known_associations.md (2026-08-07) — product → dealer mapping

The new index file 02-Clients/Agents/_known_associations.md is the canonical hook-4 output Robin needs to evaluate before the next Chinese-region dealer visit. Key mappings surfaced (5 direct hits):

Product line	261-dealer表 命中	关联客户 / 商机
CelVivo (ClinoStar / ClinoReactor)	济南成全生物科技有限公司 (曹沛起) — registered in both 华北 + 山东 (cross-region, 2 次)	董慧群关联 (待 Robin 确认是否同公司)
FemtoBiomed (CellShot / PROLIVA)	0 direct hits (9X Bio / 汇佰生物 is the direct intermediate, not in the 261 dealer list)	TriArm Therapeutics (翁靖傑, 上海 CGT/CAR-T) — 128 万 Phase1 / 8-10 至 8-14 现场 demo
3Brain (HD-MEA)	0 direct hits	—
Cellink (BIO X)	0 direct hits	—
西南医大 心研所 殴贤红	2 dealers: 成都百乐 (杨军, 钻石级 1亿, Bio-Rad / Sartorius / Oxford Nanopore / Cytek / Leica, 覆盖川渝黔藏) + 成都立德赛 (川渝云贵陕)	(待 Robin 决策)

Hook-4 questions (Robin 优先补全, per _known_associations.md):

1. 董慧群 is which specific technical contact at 济南成全 — or is she at a different CelVivo-代理?
2. 西南医大 殴贤红 → 成都百乐 vs 成都立德赛 — which dealer first?
3. 邓昊伦 (02-Contacts/) 蛇类神经方向 → 3Brain HD-MEA 拜访?
4. 261 dealer 表 has 0 3Brain / Cellink 代理 — is the dealer list incomplete, or does Robin need to actively recruit those dealers?

Log these as a new commitment on /commitments.md (distributor-8-07-association-followup) and as updates to /open-questions.md (the agent-dong-huiqun-celvivo question now partially answered — agency identified but personal contact fields still 待补).

Notable entities surfaced by the vault (structural hints only)

• 2026-08-23 root-level LDR burst (5 papers, single-shot entries, vault HEAD bump a4fa5a32 → fb017e4f) — largest single-day LDR cluster since the 2026-07-29 Parate / Lee / Hodge cluster; breaks the 7-fetch vault-silence streak that started after the 2026-08-16 Quintard + Guo cluster; all 5 files landed at obsidian-vault/04-Literature/Deep-Reads/ root (not in a per-vendor subfolder) on 2026-08-23/24 between 07:50 +0800 and 16:39 +0800; non-standard pattern vs the prior per-vendor subfolder discipline (every prior LDR cluster since 2026-07-28 has sorted into Organoid/ / Celvivo/ / 3Brain/ / Cells/ etc.). The 5 commits are all single-shot entries (no v2/v3 SOP rewrite cycles this cluster, unlike the 2026-08-16 Quintard 4-commit + Guo 3-commit pattern). Commit timestamps 2026-08-23 (Western time) + 2026-08-24 (UTC mtime): (a) ad4abcde 2026-08-24 feat: Ajongbolo 2025 Cells 脑类器官综述精读 (Wiki.js 1743) — Ajongbolo_2025_Cells_Brain_Organoids_Review.md, the canonical review paper of the cluster, 11,367 bytes; (b) 5f02489a 2026-08-24 feat: Kim 2025 NatCommun 液态金属 3D MEA 精读 (Wiki.js 1744) — Kim_2025_NatCommun_Liquid_Metal_3D_MEA.md, 13,567 bytes, the 3D-MEA competitor paper of the cluster; (c) 40b357b8 2026-08-24 feat: Tian 2025 NatCommun 心外膜 mTOR 精读 (Wiki.js 1745) — Tian_2025_NatCommun_Epicardium_mTOR.md, 15,578 bytes, the cardiac-epicardium paper of the cluster; (d) f2118a62 2026-08-24 feat: Aiello & Bagni 2025 biorxiv Rotating Chamber brain organoid 精读 (Wiki.js 1746) — Aiello_Bagni_2025_biorxiv_Brain_Organoid_Fluid.md, 11,731 bytes, the CelVivo-KB-derived brain-organoid CFD paper of the cluster; (e) fb017e4f 2026-08-24 feat: CelVivo App Note 2026 shear stress ClinoStar vs orbital shaker (Wiki.js 1747) — CelVivo_Shear_Stress_AppNote_2026.md, 10,145 bytes, the vendor App Note of the cluster. 3 of the 5 papers are CelVivo-aligned: the App Note (direct CelVivo document) + Aiello (CelVivo KB-sourced) + Ajongbolo review (mentions ClinoStar in the synthesis). 1 is a 3D-MEA competitor: Kim EGaIn magnetic-reshapable 3D MEA. 1 is a cardiac epicardium paper: Tian mTOR. The cluster anchors 4 of 5 to Robin's 4 vendor product lines (CelVivo=3, 3Brain-adjacent=1) plus 1 cardiac expansion. Synthesis routes into /themes/01-organoid-equipment.md (CelVivo evidence) + /themes/05-robin-research.md (vault-snapshot refresh + deep-reads breakdown) + /sources/literature.md (last-30-days table). Net-new external evidence in this run. Track on next fetch whether (a) more LDR files land in vault root (extending the root-level pattern) or migrate to per-vendor subfolders on next SOP revision, (b) the deepread_40240593/ pipeline workspace gets committed (per the Notable-entity entry below), (c) the existing MOC pattern at 04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md gets a 2026-08-23/24 LDR-cycle entry.
• CelVivo App Note 2026 shear stress ClinoStar vs orbital shaker (2026-08-23, single-shot LDR entry fb017e4f, Wiki.js 1747) — obsidian-vault/04-Literature/Deep-Reads/CelVivo_Shear_Stress_AppNote_2026.md (10,145 bytes). Stougaard Borgen Løschenkohl + Sedighi Frandsen, CelVivo Application Note 2026, sourced from RAGFlow CelVivo KB (1555e5b2..., Robin 8-24 上传). The note establishes head-to-head comparison of ClinoStar® vs orbital shaker for 3D 类器官/球体培养 (HepG2/C3A 15-day + embedded Caco-2 肠 + brain organoid). Core findings: (i) low shear stress ClinoStar preserves cytoskeletal integrity — phalloidin/DAPI 染色 shows ClinoStar F-actin 排列规则 + 形态紧凑 + 细胞间内聚性强 vs orbital shaker F-actin 散布 + 形态松散 + 内聚性下降 (4x + 20x dual magnification); (ii) 15-day standardized workflow — same source cells (HepG2/C3A) + same pre-conditioning (SP5D 24孔球形板 Kugelmeiers, 1000 cells/aggregate) + same end-point assays (image + ATP + BCA + fluorescent staining + microscopy) + 3 bio-replicates per condition; (iii) multi-model transferability — embedded Caco-2 肠 + brain organoid both show ClinoStar advantage → vendor claim "low shear stress sensitive cell class (肝/肠/脑来源)" validated across 3 model systems. Net-new external evidence in this run (git-repo-1 2026-08-24). Highest commercial-relevance paper of the cluster: this is the canonical CelVivo vs-orbital-shaker competitive-killer document and is Robin's first vendor App Note deep-read (vs. 1 primary research paper + 1 review paper from prior clusters). Track on next fetch whether (a) Robin produces a deep-read synthesis page at /sources/literature-celvivo-shear-stress-appnote-2026-deepread.md mirroring the prior pattern, (b) the App Note is folded into 06-Sales/Content/Training-Materials/ (the existing CelVivo赋能培训 v1-v9 cluster could absorb the head-to-head comparison data as a new PPT module), (c) the App Note spawns a new sales commitment similar to the existing celvivo-clinoreactor-thewell-bioscience-xeno-free item.
• Aiello & Bagni 2025 biorxiv Rotating Chamber brain organoid CFD (2026-08-23, single-shot LDR entry f2118a62, Wiki.js 1746) — obsidian-vault/04-Literature/Deep-Reads/Aiello_Bagni_2025_biorxiv_Brain_Organoid_Fluid.md (11,731 bytes). Aiello F, Bagni C et al., biorxiv preprint (the EMBO Reports submission version Aiello_Bagni_EMBO R_050325), 2026-08-24 Robin 从 CelVivo KB 找到的 PDF. The paper is the first CFD-quantified Rotating Chamber (RC) low-shear-stress study in Robin's deep-read set: (i) RC geometry: outer Ø 78.3 mm × H 24.2 mm, inner cavity Ø 37.7 mm × H 8.8 mm (reserved for organoid growth space); (ii) COMSOL Multiphysics 6.2 CFD simulation shows cavity shear stress < 20 mPa (extremely low vs. standard stirred/shaken systems) — first quantitative number on RC shear-stress field; (iii) multi-density organoid shear-stress validation — relative density 1010/1020/1030 vs medium 1000 confirms shear-stress uniformity across density range + 0-300 objects all experience stable low shear; (iv) morphological consistency — multi-batch + multi-cell-line brain organoid cultures show CV < 15% (vs static culture CV > 30%); (v) cortical cell type recapitulation (SOX2/Nestin/PAX6 + DCX + TBR1/SATB2/MAP2 multi-marker IHC) + scRNA-seq OXPHOS metabolic profiling. Net-new external evidence in this run. Vendor-anchor mapping: Aiello paper is CelVivo ClinoStar-adjacent (uses RC system which is the ClinoStar simplified geometry) + 3Brain HD-MEA-adjacent (cortical organoid electrophysiology read-out). The < 20 mPa quantitative claim is direct ammunition for the existing ClinoStar ⭐⭐⭐⭐ vendor-positioning pitch — no prior paper in Robin's deep-read set provides the quantitative CFD number for ClinoStar's low-shear-stress value proposition. Track on next fetch whether Robin produces a deep-read synthesis page; the deep-read pipeline currently does not carry an Aiello synthesis page.
• Tian 2025 Nat Commun hiPSC epicardium mTOR maturation (2026-08-23, single-shot LDR entry 40b357b8, Wiki.js 1745) — obsidian-vault/04-Literature/Deep-Reads/Tian_2025_NatCommun_Epicardium_mTOR.md (15,578 bytes, the largest of the 5 new LDR files). Tian Y, Lucena-Cacace A, Tani K et al., Nat Commun 2025, DOI 10.1038/s41467-025-60934-8. The paper establishes: (i) mTOR inhibition drives epicardium maturation — Torin1 (dual mTORC1/2 inhibitor, 200 nM) on mouse E12 embryonic heart explants upregulates WT1 (mature epicardium marker) + downregulates EMT markers (SNAI1/2) + downregulates cell cycle (MKI67/PCNA) + downregulates mTOR pathway; bulk RNA-seq PCA shows 28.53% (PC1) + 36.01% (PC2) variance explained = significant transcriptome shift toward adult epicardium identity; (ii) mTORC1/2 dual inhibition is critical — Rapamycin (single mTORC1) alone is insufficient; mTORC2 is the key node; (iii) hiPSC-derived epicardium maturation with Torin1 — qPCR validates mature markers (TJP1/WT1/TBX18/ALDH1A2/CDH18) up + EMT markers (SNAI1/SNAI2/CDH2/CDH1) down + proliferation markers (MKI67/PCNA/MCM2) down + fatty-acid metabolism maturation (PDK4/PPARGC1A/SIRT1/FASN/SREBF1); bulk RNA-seq with 379 DEGs; Torin1 vs adult epicardium GSE84085 heatmap confirms adult-like profile; YBX3 + MAFF identified as Torin1-specific TFs via Venn diagram + siRNA knockdown; (iv) paracrine effect on cardiomyocyte maturation — mature epicardium (Torin1-treated) co-cultured with hiPSC ventricular cardiomyocyte EBs for 10 days upregulates TNNI3 (adult cardiomyocyte marker) → epicardium-to-cardiomyocyte maturation cross-talk via paracrine signaling. Net-new external evidence in this run. Application domain: cardiac organoid regeneration; not directly anchored to CelVivo/3Brain/Cellink/Femtobiomed product lines (no vendor rating callouts in the deep-read) but fits the broad cardiac application-domain bucket that Robin's wiki scope covers. Track on next fetch whether (a) Robin produces a deep-read synthesis page, (b) the Tian paper routes into any commitment — there is no cardiac-specific commitment in /commitments.md yet.
• Kim 2025 Nat Commun EGaIn liquid-metal 3D MEA (2026-08-23, single-shot LDR entry 5f02489a, Wiki.js 1744) — obsidian-vault/04-Literature/Deep-Reads/Kim_2025_NatCommun_Liquid_Metal_3D_MEA.md (13,567 bytes). Kim E, Jeong E, Hong YM et al., Nat Commun 2025, DOI 10.1038/s41467-024-55752-3. The paper establishes: (i) EGaIn (eutectic gallium-indium) 3D pillar MEA — microfluidic direct-ink-writing fabrication with pillar height 25-310 μm controllable by printing speed (R² > 0.95, n=12 datapoints), pillar diameter down to 14 μm (single-neuron scale), parylene-C selective encapsulation with only pillar tip exposed as electrode; (ii) magnetically reshapable — Ni magnetic layer on pillar exterior + external magnetic field drives pillar bending → 3D MEA shape conforms to different organoid sizes/shapes (no fabrication re-spin needed); (iii) hPSC cortical organoid maturation timeline — Dorsomorphin + SB-431542 (dual-SMAD) → FGF2/EGF expansion → BDNF/NT3 maturation at 15/30/45/60/120 days; 30d SOX2+/TUJ1+ early neuronal; 60d SOX2↓ + TUJ1↑↑; 120d 6-marker co-expression (MAP2/GFAP/VGLUT1/SATB2/CTIP2) = cortical 6-layer-like structure; (iv) biocompatible integration — 4-month organoid seeded on 3D MEA, co-cultured 14 days; live/dead + qPCR (PAX6/Nestin/TUJ1) + IHC (Nestin/TUJ1/SOX2/MAP2/GFAP) all confirm biocompatibility; (v) single-unit spike + network synchronization recording — 64-channel MEA acquisition + SU spike detection + synchronization score + network graph analysis across 1/2/4/6 month organoid maturation. Net-new external evidence in this run. Vendor-anchor mapping: 3Brain HD-MEA competitor / adjacent paper — Kim's EGaIn 3D MEA is a next-generation flexible 3D MEA approach that is adjacent to but not directly competing with 3Brain's rigid Accura-3D chip (3Brain uses 4096-electrode planar CMOS, Kim uses 3D pillar EGaIn with magnetic reshape). The Liu 2026 NBME shape-conformal framework from the 2026-08-08 cluster is a third next-gen HD-MEA approach — 3 distinct next-gen HD-MEA approaches now in Robin's deep-read set: Liu 2026 Rogers Lab flexible-electronics framework (3000-8000 ch, >90% surface coverage) + Kim 2025 EGaIn 3D pillar (25-310 μm height, magnetic reshape) + Kim's pillar biocompatibility with cortical organoid (1/2/4/6-month maturation timeline). Track on next fetch whether (a) Robin produces a deep-read synthesis page at /sources/literature-kim-2025-nat-commun-liquid-metal-3d-mea-deepread.md, (b) the Kim paper routes into the existing liu-2026-hd-mea-roadmap-implication commitment as a corroborating evidence point (the "next-gen HD-MEA field" consolidation narrative now has 3 distinct data points), (c) the Kim paper pairs with Liu 2026 to anchor a new liu-kim-2025-2026-next-gen-hd-mea-roadmap consolidation synthesis page.
• Ajongbolo 2025 Cells brain organoid review (2026-08-23, single-shot LDR entry ad4abcde, Wiki.js 1743) — obsidian-vault/04-Literature/Deep-Reads/Ajongbolo_2025_Cells_Brain_Organoids_Review.md (11,367 bytes). Ajongbolo AO, Langhans SA, Cells 2025, DOI 10.3390/cells14110842. The paper is the canonical brain organoid + assembloid review for Robin's deep-read set: (i) 3-tier brain-organoid taxonomy — whole-brain organoid (Lancaster 2013 archetype, multi-brain-region identity, unguided spontaneous differentiation) → region-specific organoid (前脑/中脑/小脑/下丘脑 with patterning-factor-guided TF markers FOXG1 / OTX2 / EN1/EN2 / GBX2 / FGF8 / SHH) → complex organoid systems (assembloid multi-region fusion / OoC vascularization-perfusion / tumoroid tumor modeling / xenograft immunodeficient-mouse intracranial transplant); (ii) 4-class characterization methodology — morphological (IF + confocal) + biochemical (qPCR/Western/bulk RNA-seq) + functional (MEA / patch clamp / calcium imaging) + omics (scRNA-seq / spatial transcriptomics / mass spec) = standardized decision tree for any new brain-organoid line publication; (iii) disease-modeling real-world boundaries — neurodevelopmental (microcephaly / macrocephaly / ASD / Rett / Fragile X / Timothy syndrome) + neurodegenerative (AD / PD / HD / ALS) + brain-tumor (glioblastoma / medulloblastoma / AT/RT); (iv) drug-discovery pipeline standardization — 96-well + microfluidic chip + automated imaging + AI phenotype recognition → emerging HTS platform. Net-new external evidence in this run. Vendor-anchor mapping: CelVivo ClinoStar-adjacent (long-term stable brain organoid culture) + 3Brain HD-MEA-adjacent (functional electrophysiology read-out via MEA in the 4-class characterization). Cross-vendor: Ajongbolo review is the first comprehensive brain-organoid review in Robin's deep-read set since the 2026-07-29 Organoids 2026 review (10.1186_s40164-026-00743-x) — pairs with that review to give Robin a review-paper anchor for the brain-organoid lane. Track on next fetch whether (a) Robin produces a deep-read synthesis page at /sources/literature-ajongbolo-2025-cells-brain-organoids-review-deepread.md, (b) the review routes into /themes/05-robin-research.md as a "review-paper cluster" entry alongside the Organoids 2026 review.
• deepread_40240593/ pipeline workspace (2026-08-24 NEW → 2026-08-26, still uncommitted) — deepread_40240593/ is the first new untracked directory added at the 2026-08-24T18:05Z fetch, alongside the 5 root-level LDR files. The directory contains 7 subdirectories: deepread_40016200 + deepread_40441268 + deepread_40498018 + deepread_40593704 + deepread_41151577 + deepread_brain_organoid_fluid + deepread_shear_stress_cs_os. The directory is at the vault root (not in 04-Literature/); the numeric-name pattern (deepread_<PMID>) suggests Robin's LDR pipeline is using these directories as per-paper working folders — the names include both PMIDs (40016200, 40441268, 40498018, 40593704, 41151577) and human-readable slugs (brain_organoid_fluid → maps to Aiello paper; shear_stress_cs_os → maps to CelVivo App Note). The directory mtime is 2026-08-24 16:31 +0800 (still 2026-08-26 at this fetch — directory mtime unchanged across the 2026-08-25 + 2026-08-26 fetches, no pipeline activity since initial creation). Structural significance (carried forward from 2026-08-24): (a) the deepread_<PMID> naming convention is not the prior 04-Literature/Deep-Reads/<vendor>/ convention — the new pattern is a per-paper working-folder pattern that holds pipeline intermediate artifacts (PDFs, image-extracts, qa-pass outputs, Ollama vision-audit intermediates, etc.) before final commit to 04-Literature/Deep-Reads/. (b) The presence of 5 already-committed root-level LDR files (in 04-Literature/Deep-Reads/) plus the 2 named deepread_<slug> folders (brain_organoid_fluid + shear_stress_cs_os) — which exactly map to 2 of the 5 committed papers — suggests Robin's pipeline writes the committed LDR note to 04-Literature/Deep-Reads/ and the intermediate artifacts to deepread_40240593/deepread_<slug>/; the other 5 PMID-named subdirs are pipeline intermediates for 5 other in-progress papers not yet on main. (c) The vault-root deepread_40240593/ is not yet committed (carry-forward untracked); the 2026-08-23 7-paper burst + the 2026-08-24/25 SECOND 5-paper burst means Robin is producing pipeline output faster than the manual commit cycle — no commit despite a SECOND 5-paper burst landing at vault HEAD. Carry-forward status (2026-08-26): untracked, 3-day carry-forward (was 2-day at the 2026-08-25T18:13Z fetch, 1-day at the 2026-08-24T18:05Z fetch), future-commit candidate; 2 fetches silent since the SECOND 5-paper burst landed. Watchlist signal at the 2026-08-26 fetch: the deepread_40240593/ directory has not been committed despite the 2026-08-24/25 cluster producing 5 more committed LDR files, none of which appear to have routed through deepread_<slug>/ working folders (the directory mtime is still 2026-08-24 16:31 +0800, unchanged since initial creation); the working-folder pipeline hypothesis has weakened evidence at this fetch — if Robin had used the working folders for the 2026-08-24/25 burst, the directory mtime would have advanced to 2026-08-25 +0800; the absence of mtime movement in the 2026-08-25 + 2026-08-26 fetches suggests the working-folder pipeline may have been abandoned, formalized differently, or batched without intermediate commit. Track on next fetch whether (a) the directory is committed, (b) the directory mtime finally advances (which would re-strengthen the working-folder pipeline hypothesis), (c) the deepread_<PMID> vs 04-Literature/Deep-Reads/<slug> separation is formalized in vault conventions, (d) Robin documents the working-folder pipeline somewhere (commit message / vault README / blog post). No synthesis routes until the directory is committed.
• 2026-08-24/25 cluster — SECOND consecutive single-day 5-paper LDR burst (vault HEAD fb017e4f → 9d4767c7, 5 new vault commits) — the 2026-08-25T18:13Z fetch observed a SECOND consecutive single-day 5-paper LDR burst at vault HEAD. Combined with the 2026-08-23/24 5-paper burst, 10 LDR files in 48 hours, the largest sustained 2-day research output in Robin's vault activity log; the cluster creates 3 NEW 04-Literature/Deep-Reads/ subfolders: Vascularized-Organoids/ (Tevonian + Shen) + Cardiac-Organoids/ (Yang) + Skin-Organoids/ (Zhai) — Robin expands the deep-read folder taxonomy from ~19 to ~22 in a single day, returning to the per-vendor / per-application-domain subfolder discipline after the 2026-08-23/24 5-paper vault-root burst (the only LDR cluster that landed at the root of 04-Literature/Deep-Reads/ rather than in a subfolder). The 5-commit cluster is (chronological): 089177a7 Tevonian 2026 Nat Commun 血管化肝 MPS deep read (PMID 41634021) → 583859a8 Yang 2026 Stem Cell Res Ther cardiac organoid review (PMID 41963991) → 9aa2af4c Update Tevonian 2026 + Yang 2026 (CelVivo/Cellink/Mimetas/3Brain/Femtobiomed product mapping retrofit + 净化 Robin mentions — FIRST post-publish vendor-mapping retrofit commit in Robin's LDR pipeline) → 5907cdfc Shen 2026 Chin Med J vascularized organoids review (PMID 42268296) → 9d4767c7 Zhai 2026 Sci Adv 3D skin pemphigus (PMID 41512055). Vendor anchor mapping (via 9aa2af4c retrofit): 4-vendor (CelVivo / Cellink / Mimetas / 3Brain / Femtobiomed) product mapping applied retroactively to Tevonian + Yang files. Net-new external evidence in this run. Synthesis routes into /themes/01-organoid-equipment.md (vascularized liver MPS + cardiac organoid review + autoimmune dermatology adjacency — likely the first significant expansion of Robin's coverage outside the canonical 4 application domains), /themes/05-robin-research.md (vault-snapshot refresh + the 2.5x expansion of subfolder taxonomy), /sources/literature.md (last-30-days table), /commitments.md (4 new commitment rows), /themes.md (potential class-organoid-3d-bioprinting evidence footprint strengthening — 4 of 5 papers are tissue-organoid deep-reads; if the 2026-08-25 burst recurs, the theme row may need a deeper evidence-footprint refresh). Track on next fetch whether (a) more per-vendor / per-application-domain subfolders land (extending the post-root-burst return to subfolder discipline), (b) the 9aa2af4c retrofit pattern is applied to the prior 5 papers from the 2026-08-23/24 cluster (currently only Tevonian + Yang got the retrofit), (c) the Vascularized-Organoids/ + Cardiac-Organoids/ + Skin-Organoids/ subfolders accumulate additional entries (≥3 total entries per subfolder is the threshold for "subfolder is in active use"), (d) the deepread_40240593/ pipeline workspace directory finally gets committed.
• Tevonian 2026 Nat Commun 血管化肝 MPS (2026-08-25, single-shot LDR entry 089177a7, PMID 41634021) — obsidian-vault/04-Literature/Deep-Reads/Vascularized-Organoids/Tevonian_2026_Nat_Commun_Vascularized_Liver_MPS.md. Tevonian et al. (2026) Nat Commun — first vascularized liver MPS (microphysiological system) paper in Robin's deep-read set. Vendor anchor mapping (via 9aa2af4c retrofit): the retrofit commit added the 5-vendor product mapping table (CelVivo + Cellink + Mimetas + 3Brain + Femtobiomed) to the file; the deep-read likely ranks Mimetas OrganoPlate for the multi-channel vascularized MPS architecture (OrganoPlate is the canonical microphysiological system for vascularized liver tissue) + CelVivo ClinoReactor for upstream hepatocyte maturation (Hep-Orgs source) + Cellink BIO X for the decellularized liver scaffold matrix. Companion to the existing Liang 2026 liver organoid entry (ClinoStar ⭐⭐⭐⭐ for P1-P10 long-term maturation + ClinoReactor ⭐⭐⭐⭐ for 3-track HEP/CHO/HSC perfusion). Application domain: vascularized liver — extends the existing Liver/ subfolder's (6 papers) fibrotic disease modeling story with a vascularization dimension. Net-new external evidence in this run (git-repo-1 2026-08-25). Synthesis routes into /themes/01-organoid-equipment.md (vascularized liver vendor mapping) + /commitments.md (new commitment entry once Robin produces a synthesis page). Track on next fetch whether (a) Robin produces a deep-read synthesis page at /sources/literature-tevonian-2026-nat-commun-vascularized-liver-mps-deepread.md, (b) the retrofitted 5-vendor mapping tables yield specific ROI for the active CelVivo / Cellink / Mimetas / 3Brain / Femtobiomed Chinese pharma R&D / CDMO account targeting, (c) the Tevonian paper pairs with Shen 2026 to anchor a vascularized-organoid review-paper cluster that the existing Subfolder lacks.
• Yang 2026 Stem Cell Res Ther cardiac organoid review (2026-08-25, single-shot LDR entry 583859a8, PMID 41963991) — obsidian-vault/04-Literature/Deep-Reads/Cardiac-Organoids/Yang_2026_Stem_Cell_Res_Ther_Cardiac_Organoid_Review.md. Yang L et al. (2026) Stem Cell Res Ther — first comprehensive cardiac organoid review in Robin's deep-read set. Vendor anchor mapping (via 9aa2af4c retrofit): the retrofit commit added the 5-vendor product mapping table to the file. Companion to Tian 2025 Nat Commun (the cardiac epicardium mTOR paper from the 2026-08-23 burst) which established the actual mechanistic depth; Yang 2026 is the canonical review that contextualizes Tian alongside the prior cardiac organoid literature (hPSC cardiac organoid generation methods, maturation protocols, disease modeling applications, regenerative medicine routes). Application domain: cardiac organoid — Robin expands from the prior 2-paper Cardiac/ subfolder to a dedicated Cardiac-Organoids/ subfolder; this is the first time Robin has opened a new subfolder explicitly for an application-domain cluster (prior new subfolders have been for review types or vendor types). Net-new external evidence in this run (git-repo-1 2026-08-25). Synthesis routes into /themes/01-organoid-equipment.md (cardiac organoid vendor mapping) + /commitments.md (new commitment entry) + /sources/literature.md (last-30-days table). Track on next fetch whether (a) Robin produces a synthesis page at /sources/literature-yang-2026-stem-cell-res-ther-cardiac-organoid-review-deepread.md, (b) the cardiac-organoid commitment folds Tian + Yang as a paired mechanistic + review cluster, (c) the Cardiac-Organoids subfolder accumulates ≥3 entries.
• Shen 2026 Chin Med J vascularized organoids review (2026-08-25, single-shot LDR entry 5907cdfc, PMID 42268296) — obsidian-vault/04-Literature/Deep-Reads/Vascularized-Organoids/Shen_2026_Chin_Med_J_Vascularized_Organoids_Review.md. Shen Y et al. Chin Med J 2026 — Chinese-language peer-reviewed vascularized organoid systematic review; companion to Tevonian 2026 in the same cluster. Vendor anchor mapping: TBD; the deep-read is in the Chinese-language journal 中华医学杂志 (English edition) which makes it a credential Chinese-hospital-academic source for Robin's active Chinese pharma R&D / CDMO customer base. Application domain: vascularized organoid — adds a 2-paper cluster to the new Vascularized-Organoids/ subfolder. The Shen 2026 review is the review-paper anchor for the new subfolder (review-type) and the Tevonian 2026 primary research paper is the research-paper anchor (primary-type). Net-new external evidence in this run. Track on next fetch whether Robin produces a deep-read synthesis page and whether the Chinese-language source yields any CelVivo-specific IRB or vascularization positioning material.
• Zhai 2026 Sci Adv 3D skin pemphigus (2026-08-25, single-shot LDR entry 9d4767c7, PMID 41512055) — obsidian-vault/04-Literature/Deep-Reads/Skin-Organoids/Zhai_2026_Sci_Adv_3D_Skin_Pemphigus.md. Zhai T et al. Sci Adv 2026 — first 3D-skin organoid disease-modeling paper in Robin's deep-read set; net-new application domain (autoimmune dermatology + 3D skin) that Robin's existing ~22 deep-read subfolders do not cover. Vendor anchor mapping: TBD; the deep-read does not have the 9aa2af4c retrofit 5-vendor mapping (the retrofit was applied only to Tevonian + Yang); skin organoid is a candidate workflow for CelVivo ClinoReactor (long-term 3D skin culture — similar to the existing liver, brain, lung, retinal organoid applications) but the Sci Adv paper's specific ClinoReactor / ClinoStar callouts are not in the manifest entry. Application domain: 3D skin organoid + autoimmune dermatology (pemphigus) — distinct from the existing Cancer / Brain / Liver / Vascularized-Organoids / Cardiac-Organoids / Kidney / Retinal / Brain-Tumor application-domain subfolders. Net-new external evidence in this run. Synthesis routes into /themes/01-organoid-equipment.md (autoimmune dermatology adjacency to the vascularized-organoid cluster) + /commitments.md (new commitment entry). Track on next fetch whether (a) Robin produces a deep-read synthesis page, (b) the Skin-Organoids subfolder accumulates ≥3 entries to confirm a recurring application-domain pattern, (c) the Zhai paper yields Chinese cosmetic / dermatology pharma R&D positioning material that the active CRM portfolio could absorb.
• 9aa2af4c post-publish vendor-mapping retrofit commit (2026-08-25, NEW SOP step in Robin's LDR pipeline) — 9aa2af4c is a non-paper-content commit that touches the Tevonian 2026 + Yang 2026 files in-place to add the 5-vendor product mapping table (CelVivo / Cellink / Mimetas / 3Brain / Femtobiomed) plus 净化 Robin mentions (sanitization of any "Robin" / "Robin 8-XX 实战沉淀" attribution strings that might leak into the production deep-read narrative). The commit is the first post-publish vendor-mapping retrofit in Robin's LDR pipeline; the prior 5-paper 2026-08-23/24 cluster (Ajongbolo + Kim + Tian + Aiello + CelVivo App Note) did NOT receive the retrofit — only the new Tevonian + Yang pair got the retroactive 5-vendor mapping. The retrofit is methodologically significant: it indicates Robin's LDR workflow is now adding a post-publish vendor-mapping step to the standard 8-step SOP (the 8 铁律 + 3 trigger modes + 5-section report pattern at /sources/ldr-report-template.md). The prior 8-step SOP does not include a vendor-mapping retrofit step — Robin has effectively iterated to a 9-step SOP for the new Tevonian + Yang pair. The retrofit's 净化 Robin mentions specifically addresses the "客户-facing deep-read 净化" concern flagged in the prior synthesis policy — Robin's deep-reads are increasingly being routed into customer conversations (the Guo 2026 IRB checklist template is the canonical example) and any Robin attribution in the body could break the "vendor-anchored customer-facing artifact" framing. Track on next fetch whether (a) the 9aa2af4c retrofit pattern is applied retroactively to the prior 5 papers (Ajongbolo + Kim + Tian + Aiello + CelVivo App Note) — if Robin retro-fits the vendor mapping, the existing class-organoid-3d-bioprinting theme evidence footprint strengthens materially; if not, the retrofit might be an LDR-pipeline ad-hoc patch rather than a recurring pattern; (b) the 9aa2af4c retrofit becomes a standard LDR step (replacing the existing 8-step SOP iteration pattern); (c) the LDR SOP iteration is documented at /sources/ldr-report-template.md and /sources/2026-07-27-4-27-sop-vs-implementation.md.
• Quintard 2024 Nat Commun microfluidic vascularized organoid chip (2026-08-16, 7 commits in 48-hour window) — obsidian-vault/Literature/Deep-Reads/Organoid/quintard_2024_vasorganoid_chip.md (189 lines; 4-commit LDR cycle 0fc8db24 adds → 290e9635 -v2 修图床/双 H1/落款 → 24c713de -v3 Wiki.js 自带图床 6 张图 → 4073abf4 -v4 转发语标题/落款加粗/删 3Brain; Wiki IDs 1719/1720/1722, NocoDB Id 3297). The paper is the first microfluidic / organ-on-chip platform paper Robin has deep-read in the 2026-08 window; the platform combines (i) 10-channel parallel microfluidic chips with U-shaped capture sites (300-800 µm adjustable), (ii) fibrin + Matrigel hydrogel layer deposition using Landau-Levich-Bretherton effect, (iii) ~10 s capture efficiency ~100%, (iv) dynamic perfusion 7-30 days with HUVEC + fibroblast co-culture + hiPSC-derived BVO + islet spheroid + lung organoid cross-validation, (v) hierarchical vasculature (37 µm upstream artery-vein + 8 µm BVO capillaries, matching physiological ranges 50-1900 s⁻¹). Net-new external evidence in this run (git-repo-1 2026-08-17). The 4-star "与我们的产品" table lists Mimetas OrganoPlate ⭐⭐⭐⭐ (direct Phaseguide-based vascularized / kidney / intestine organ-on-chip competitor) + CelVivo ClinoStar ⭐⭐⭐ (upstream workflow step: BVO differentiation day 0-15 needs rotating-wall suspension culture; ClinoStar is the canonical hardware for this stage; the paper's day 15 → chip-on-board handoff is the canonical CelVivo → organ-on-chip workflow) + Emulate Organ-Chip ⭐⭐⭐ (Colon-Intestine-Liver platform companion). Synthesis routes into /themes/05-robin-research.md (新增 by-vendor entry) and /sources/literature.md (last-30-days deep-read table). Vendor-anchor mapping: CelVivo-adjacent (workflow upstream) + Mimetas OrganoPlate / Emulate Organ-Chip (organ-on-chip product lane that Robin's portfolio does not currently cover but represents a potential cross-sell if Robin's customers ask "where do I run my CelVivo-matured organoids in a vascularized microenvironment?"). Customer-entry: 药企临床前 (vascularized drug screening) + 微流控 organ-on-chip 平台集成商 (Mimetas / Emulate channel partners) + academic PI (vascular development / diabetes). Track on next fetch whether Robin publishes a /sources/literature-quintard-2024-nat-commun-vasorganoid-chip-deepread.md synthesis page; the deep-read pipeline currently only carries liang-2026-celvivo-clinostar-positioning + miao-2025-celvivo-clinostar-positioning + liu-2026-hd-mea-roadmap-implication + sharma-2026-retinal-organoid-mea-cross-sell — no Quintard synthesis page yet.
• Guo 2026 Front Cell Dev Biol organoid ethics systematic review (2026-08-16, 7 commits in 48-hour window) — obsidian-vault/Literature/Deep-Reads/Organoid/guo_2026_organoid_ethical_review.md (170 lines + 3 真图; 3-commit LDR cycle 2e6f5989 adds → 00f824f2 -v2 修图床 (加 2 张 Wiki.js 自带图) → a4fa5a32 -v3 补 Fig 1; Wiki ID 1724, NocoDB Id 3298). The paper is the first organoid-research ethics / IRB systematic review Robin has deep-read in any window — fills the methodological gap on the IRB-side that the prior clinical-translation evidence (CDE classification + Order No. 818) does not directly cover. The paper structures the IRB review framework as 7 mandatory points (sample provenance + donor informed consent + data privacy & de-identification + co-culture agency + animal welfare 3R + cross-border regulation + long-term storage & termination); the cross-border table compares China (《人类遗传资源管理条例》+ 《涉及人的生命科学和医学研究伦理审查办法》2023), US (HIPAA + Common Rule + NIH GDS), EU (GDPR + Clinical Trials Regulation 536/2014), Japan, Korea. The 4-star "与我们的产品" table lists CelVivo ClinoStar ⭐⭐⭐⭐ (clinical-translation IRB compliance — the 7 mandatory points directly apply to ClinoStar customer IRB submissions; Robin 推广 ClinoStar 给三甲医院时, 可附带本框架作为增值) + Mimetas OrganoPlate ⭐⭐⭐⭐ (co-culture ethics — Mimetas 主营类器官 + 免疫细胞共培养, the co-culture agency framework from Guo 2026 point 4 directly applies) + Emulate Organ-Chip ⭐⭐⭐ (organoid + microfluidic cross-border regulation reference). Net-new external evidence in this run (git-repo-1 2026-08-17). Robin translated the paper into a customer-facing sales ammunition template at templates/类器官IRB申请清单.md (180 lines; 7 mandatory points checklist + 5 customer Q&A + China vs International flow table + 10 attachments + 7 citations; v1.0 dated 2026-08-16, "Robin 8-16 实战沉淀") — see the templates/ entry in the next bullet. Customer-entry: 临床转化型医院 (class A tertiary hospitals running organoid IRB submissions) + 类器官厂家 Robin 培训客户 (the IRB checklist is the canonical "Robin 培训客户 IRB 申请" core material) + academic PI (cross-border collaboration IRB paperwork). Track on next fetch whether (a) the templates/ IRB checklist gets committed, (b) the Robin-author attribution in the template is recognized as a wiki-side customer-training artifact, (c) Robin produces a deep-read synthesis page at /sources/literature-guo-2026-front-cell-dev-biol-organoid-ethics-deepread.md, and (d) the IRB checklist routes into the existing CelVivo industrial-customers program (which currently lives at 05-Documents/Products/Celvivo/Industrial-Customers/) as a standard customer-training artifact.
• Review/ subfolder — first entry (2026-08-13, still uncommitted at 2026-08-26, 15-day carry-forward, watchlist signal continuing to weaken) — obsidian-vault/04-Literature/Deep-Reads/Review/zhou2023_computer_vision_microfluidics.md is the first file in a new Review/ subfolder under 04-Literature/Deep-Reads/. The file is untracked at the 2026-08-26 fetch (Robin has not yet committed it — same state as the 2026-08-13 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 + 2026-08-26 fetches, 0 progress in the 2026-08-13 → 2026-08-26 312-hour window, 13 consecutive fetches silent on the file). Watchlist signal continuing to weaken at this fetch: per the 2026-08-15 watchlist-trigger rubric ("if the file remains uncommitted at the next fetch (2026-08-17 or later), the structural signal weakens"), the Review/ subfolder at the 2026-08-26 fetch is still single-entry, still untracked — the structural signal continues to weaken at this fetch (15-day carry-forward with no commit, no follow-up paper landed in the subfolder across 13 consecutive fetches). The Review/ subfolder is more likely to be a one-off than a recurring pattern. The file should either be committed on a future fetch (which would re-strengthen the signal) or remain untracked indefinitely (which would confirm the one-off interpretation). Watchlist downgrade consideration at the 2026-08-26 fetch: with the structural signal continuing to weaken for 13 consecutive fetches with no follow-up paper landing in the subfolder (and 4 consecutive bursts of LDR activity landing at the vault HEAD without routing any review-type paper to the Review/ subfolder), the Review/ subfolder entry's watchlist status is approaching a downgrade-to-stale threshold; a 2026-08-27 fetch that lands the file as still-uncommitted would confirm the one-off interpretation and the entry should be demoted to a "stale / not recurring" carry-forward note rather than an active watchlist entry. No synthesis routes until the file is committed.
• templates/ subfolder — first entry (2026-08-16, NEW → 2026-08-26, still uncommitted) — templates/类器官IRB申请清单.md (180 lines, mtime 2026-08-16, untracked) is the first file in a new templates/ directory at the vault root. The file is Robin's first customer-facing sales ammunition template produced from a single deep-read (the Guo 2026 IRB ethics systematic review). Content: 7 mandatory IRB review points checklist (样本来源/知情同意/数据隐私/共培养主体性/3R 动物福利/跨境监管/长期保存与终止使用) + 5 customer Q&A ("类器官研究要不要 IRB 申请?" / "类器官共培养产品怎么申请 IRB?" / "类器官跨境研究怎么报?" / "3R 原则怎么写?" / "类器官 + 免疫细胞共培养 = CAR-T 体外培养, 算不算新生物体? 伦理上算什么?") + China vs International flow comparison table + 10-row 申请附件清单 + 7 references (Guo 2026 + ISSCR 2021 + OHRP 2016 + GDPR 2018 + China 2023 + China 2019 + Cambridge 2020). The template's version: v1.0 (2026-08-16, Robin 8-16 实战沉淀) and Robin 业务定位: 类器官厂家给三甲医院 IRB 申请的标准模板 + Robin 客户培训材料核心 framing makes it explicit that this is the canonical "Robin 培训客户 IRB 申请" core material. Structural significance (carried forward from 2026-08-16): the templates/ directory is new — none of the existing top-level folders (01-Active-Sales/ / 02-Clients/ / 02-Active-Deals/ / 02-Contacts/ / 03-Product/ / 03-Resources/ / 04-Literature/ / 05-Documents/ / 06-Sales/ / 99-Templates/ / memory/) provides a vendor-agnostic customer-training-artifact slot at the vault root. The Obsidian vault already has 99-Templates/ for reusable Obsidian templates (note templates, daily-report templates — per 99-Templates/ size hint 14 .md), but the new templates/ directory is for customer-facing sales ammunition, not Obsidian note templates — a different artifact type. The naming convention overlaps with 99-Templates/ and may need disambiguation; Robin's intent (per the file header) is for this templates/ to be the canonical customer-training artifact directory, distinct from 99-Templates/ Obsidian-note templates. Customer-entry scenarios called out in the template: (a) 类器官厂家研发负责人 = IRB 申请准备, (b) Robin 客户开发 = 培训客户 IRB 申请核心材料, (c) 医院 IRB 委员会 = 类器官研究 IRB 审查标准参考, (d) 学术合作方 = 跨境合作时多国法规差异对照. Carry-forward status (2026-08-26): untracked, 10-day carry-forward since first observation (was 9-day at the 2026-08-25T18:13Z fetch, 8-day at the 2026-08-24T18:05Z fetch, 7-day at the 2026-08-23T18:11Z fetch, 6-day at the 2026-08-22T18:13Z fetch, 5-day at the 2026-08-21T18:09Z fetch), future-commit candidate; 9 fetches silent since the directory first appeared (first observed at the 2026-08-17T18:09Z fetch). The file mtime is still 2026-08-16 +0800 (unchanged since initial creation) — no template authoring activity since the original 2026-08-16 creation, despite 4 consecutive bursts of LDR activity (Quintard + Guo 2026-08-16 + the 2026-08-23 5-paper burst + the 2026-08-25 5-paper burst) that could have generated follow-up templates. Watchlist signal weakening (similar to the Review/ subfolder): the templates/ directory has remained single-entry + uncommitted for 10 consecutive fetches with no follow-up template landing despite multiple LDR bursts that could plausibly have generated sales ammunition templates. The directory is approaching a "one-off" interpretation. Track on next fetch whether (a) Robin commits the file to main, (b) more templates land in the directory (extending the customer-training-artifact slot), (c) the templates/ and 99-Templates/ naming overlap gets resolved (rename / docs / conventions), (d) any of the 4 prior LDR bursts produces a follow-up template (which would re-strengthen the sales-ammunition-pipeline hypothesis). Synthesis routes into /themes/05-robin-research.md (sales ammunition pipeline section).
• celvivo_commercial/ subfolder — first entry (2026-08-17, NEW → 2026-08-26, still uncommitted) — celvivo_commercial/1331651_20260630_131201.pdf (56 KB PDF, mtime 2026-08-17, untracked) is the first file in a new celvivo_commercial/ directory at the vault root. The PDF is the existing 6-30 quote PDF that Robin migrated into a new folder. The file is a quote PDF, not a synthesis target — the on-disk evidence is the existing 6-30 quote document that already exists in 05-Documents/Products/Celvivo/Industrial-Customers/ (per the 2026-08-15 synthesis-policy section above, "commercial docs (8 files: Exhibit 1 Price Book / Exhibit 3 SuperUser certification / Huibai demo discount agreement / 惠百 PO 盖章版 / Celvivo Distribution Agreement 2026 Huibai Bio / 1331651_20260630_131201 (6-30 quote) / Packing Slip Ordre 726_1 / Packing Slip Ordre 726_2)"). Structural significance (carried forward from 2026-08-17): the celvivo_commercial/ directory is new — Robin has migrated the 6-30 quote out of wherever it was previously (presumably a working folder or 05-Documents/Products/Celvivo/ deep path) into a top-level dedicated directory. The migration is unfinished — only 1 file in the new directory; if Robin intends the directory to consolidate all 8 commercial docs from 05-Documents/Products/Celvivo/Industrial-Customers/, the other 7 files (Exhibit 1 Price Book / Exhibit 3 SuperUser certification / Huibai demo discount agreement / 惠百 PO 盖章版 / Celvivo Distribution Agreement 2026 / Packing Slip Ordre 726_1 / Packing Slip Ordre 726_2) should eventually land here too. No synthesis routes until Robin commits the file or migrates more docs into the directory. Carry-forward status (2026-08-26): untracked, single-entry, 10-day carry-forward since first observation (was 9-day at the 2026-08-25T18:13Z fetch, 8-day at the 2026-08-24T18:05Z fetch, 7-day at the 2026-08-23T18:11Z fetch, 6-day at the 2026-08-22T18:13Z fetch, 5-day at the 2026-08-21T18:09Z fetch); 9 fetches silent since the directory first appeared (first observed at the 2026-08-17T18:09Z fetch). The file mtime is still 2026-08-17 +0800 (unchanged since initial creation) — no commercial-doc migration activity since the original 2026-08-17 migration, despite the 2026-08-25 SECOND 5-paper burst landing 5 more LDR commits in the vault (none of which involved commercial-doc migration). Watchlist signal weakening (similar to the Review/ + templates/ subfolders): the celvivo_commercial/ directory has remained single-entry + uncommitted for 10 consecutive fetches with no follow-up commercial-doc migration despite 4 LDR bursts landing at vault HEAD; the directory is approaching a "one-off" interpretation. Track on next fetch whether (a) the file gets committed, (b) more commercial docs migrate into the directory (which would re-strengthen the consolidation hypothesis), (c) the directory mtime finally advances.
• 2026-08-15 sources-sync bug — count-data wipe (operational) — the 2507925e27b83b4f9d2e6f3b9c939d081a90f9f2 chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-15) commit at 2026-08-15 +0800 02:31 committed empty count values for NocoDB / Wiki.js / RAGFlow (SeaFile was already empty so the commit was a no-op there): (a) NocoDB: 6614 → 0 total records, with all 13 per-table counts (brain_organoid_literature / intestinal_organoid_literature / Celvivo_literature / cardiac_organoid_literature / cancer_organoid_literature / liver_organoid_literature / other_organoid_literature / kidney_organoid_literature / retinal_organoid_literature / Cellink_literature / organoid_literature_old / lung_organoid_literature / 3Brain_literature) cleared to empty cells; (b) SeaFile: libraries table unchanged (was empty in 1737454 already — a separate, older cron issue not introduced by 2507925); (c) Wiki.js: 83 → 0 unique pages, ID range 22..1704 → 0..0, Locale 分布 → empty, Top-level 路径分布 → empty; (d) RAGFlow: landing 200 → 000, /api/v1/health 404 → 000, /api/v1/datasets 401 → 000. The header lines on each affected /sources/{nocodb,ragflow,seafile,wikijs}.md page still report 上次同步: 2026-08-14T18:30:42Z (the prior successful sync timestamp), but the body count values are wiped. Probable root cause: the auto-source-sync CRON job ran but the underlying NocoDB / Wiki.js / RAGFlow API calls failed (likely the same operational issue already documented on /sources/web-search.md and /sources/README.md — runtime registry disagreement on enabled: true vs. disabled); the script committed the empty values instead of skipping the commit on failure. Impact: 3 source pages now show misleading zero/null values (NocoDB / Wiki.js / RAGFlow); Tavily / HN / git-repo synthesis is unaffected. Recovery: the wiped data is recoverable from the prior wiki commit (git show 1737454:sources/nocodb.md etc. will restore the pre-wipe state). This run restored the wiped data on all 3 affected pages (plus an operational note documenting the bug) so the wiki is internally consistent again. Wiki-synthesis concern: none — the synthesis layer (themes / commitments / open-questions / personal-logistics) is independent of the source-page counters. Operational concern: yes — the auto-source-sync job should (a) check connectivity before committing, (b) skip the commit on API failure rather than committing empty values, or (c) preserve the prior counter values when a fresh pull returns null/empty. Recorded for traceability here + on each affected /sources/{nocodb,ragflow,seafile,wikijs}.md page.
• Liang 2026 liver organoid fibrosis platform (2026-08-12) — 04-Literature/Deep-Reads/Liver/2026-08-12_Liang_2026_SciRep_liver_organoid_fibrosis_platform.md (170 lines; [[MOC-类器官与3D培养]] already names this paper via related: back-link). The paper is the net-new external evidence this run (git-repo-1 2026-08-12) brought into the vault; see synthesis at /themes/01-organoid-equipment.md § CelVivo evidence (added 2026-08-12) and /commitments.md liang-2026-celvivo-clinostar-positioning. Single-paper LDR cycle: 4 commits (e542c977 → 8699a154 → aacba7aa → 297f106d) walked Robin's standard 3-stage SOP on the same file (186 lines → 105+/122- page 946 rewrite → page 934 修齐 micro-revisions). The 4-star "与我们的产品" table on the paper lists CelVivo ClinoStar ⭐⭐⭐⭐ (P1-P10 长程扩增对应旋转培养 30+ 天无剪切; HSC 静止态在模拟微重力下 7+ 天维持) + CelVivo ClinoReactor ⭐⭐⭐⭐ (单组织 3 轨道分通道灌流; TGFβ 时间程序精确切换) — parallel CelVivo ClinoStar rating 5 to Miao 2025 v2's ClinoStar rating 5 from the 2026-08-08 flywheel-sync, but for liver organoid (long-term maturation + fibrosis modeling) rather than lung organoid (vascularization). 7 SeaFile Fig (Fig1-7) + 4-paper 参考文献 (Huch 2013 / Huch 2015 / Clevers 2016). Customer-entry: 药企临床前 (抗纤维化药筛) + 临床肝活检中心 (1-2 mg → 3 周药敏) + 学术 PI (2D vs 3D 旋转 efficiency). MOC linkage: the paper's related: field already names [[MOC-类器官与3D培养]] (the first MOC, created 2026-08-10) — confirming the MOC pattern is in active use on real deep-reads.
• CelVivo industrial customers program — a dedicated subfolder under 05-Documents/Products/Celvivo/Industrial-Customers/ holds CelVivo_中国工业 客户开发研究报告 (v1 + v2), 客户管线定位_1页图, and 工业客户开发手册-v3. This is a self-contained CelVivo China commercial effort.
• CelVivo sales training cluster — 06-Sales/Content/Training-Materials/ contains a Robin稿生成通字稿 family (v3–v6), a CelVivo赋能培训 PowerPoint family (v1–v9, depth-flavored edits), and a 销售基础话术包 pair. Versions progress from 基础 → 5大管线 → 深度版 → 终稿修正 → 销量仅看.
• 3Brain end-customer dossier set — 11+ dossiers under 03-Resources/End-Customers/ covering 神经所 (上海), 北京大学, 北京天坛医院, 浙大一附院, 中科院昆明动物所, 西南医科大学, 贵州医科大学, plus TCM accounts at 云南中医药大学 and 天津创新中药.
• CelVivo distributor technical contact (2026-07-28, partially resolved 2026-08-07) — 02-Clients/Agents/董慧群.md is the first profile under the 02-Clients/Agents/ bucket (frontmatter type: agent, role: 代理商技术同事, products: CelVivo ClinoStar / ClinoReactor). The 2026-08-07 _known_associations.md index now identifies the CelVivo dealer as 济南成全生物科技 (曹沛起) — the only ClinoStar agent in the 259-dealer list, registered in both 华北 + 山东. Robin still needs to confirm: (a) is 董慧群 the same agency? (b) phone / WeChat / served end-customers / opportunities. The agency-side gap is now closed.
• ITX 24h host build (first observed 2026-07-31; still untracked) — 03-Resources/ITX-24h-Host/ITX_24h_Host_v18_Config_2026-07-31.md is a top-level bucket first observed between the 2026-07-30T18:13 fetch and the 2026-07-31T18:08 fetch; it remains untracked. Single file: Robin's personal 24h server build plan for hosting Hermes Agent + AI workflow stack — mATX + i5-12400 + DDR4-2666 32G + 板载 Realtek 1Gb + Intel PRO/1000 GT 双网卡 NAS 隔离, ¥2,985.82, 10/11 parts arrived, planned hostnames/roles: 192.168.31.100 (主力机 SSH) vs 10.10.10.254 (RAGFlow / NAS RAGFlow API). Workflow-tooling priority LOW (not vendor-anchored), so it does not earn a /themes.md row, but the build remains a source-anchored personal-infra work item and was promoted to /commitments.md as itx-24h-host-build-2026-q3 (Owner: me) for the post-assembly steps (Ubuntu Server 22.04 install + 双网卡静态 IP + Hermes Agent install + 24h soak test).
• Cells + 2026-08-08 cluster — Fernandez Vallone 2026 Cells (hiPSC brain organoids for THSDC chemical screening, NAMs platform) is the first 04-Literature/Deep-Reads/Cells/ entry. New application domain (toxicology + NAMs) compared to the prior Brain / Cancer / Liver buckets. CelVivo + 3Brain application scenarios called out in tags.
• Microbioreactor + 2026-08-07 cluster — Rosero 2026 Front Bioeng Biotechnol Microbioreactor design Mini Review is the first 04-Literature/Deep-Reads/Microbioreactor/ entry. Cross-vendor adjacent (CelVivo ClinoStar / Cellink BIO X / FemtoBiomed CellShot). Landed in NocoDB Robin_Picked_Papers (PMID 42516424, Wiki.js ID 1696).
• Parfitt 2024 Nat Commun (DJ1 LOF midbrain organoid + PD) — untracked file 04-Literature/Deep-Reads/Brain/2026-08-06_Parfitt_GM_et_al_NatCommun_2024_DJ1_LOF_midbrain_organoid_PD.md (15,972 bytes, mtime 2026-08-06). DJ1 LOF through astrocyte lysosomal dysfunction → AGE → α-syn → DA neuron death; CelVivo + 3Brain application scenarios in tags. Not yet on main; pending Robin commit.
• CellSweep — referenced in the wiki goal focus areas; not surfaced as a top-level vault folder in this run, so it likely lives under Work/ or scripts/ (outside the navigation index).
• Phase A metadata batch + first MOC (2026-08-10) — Robin ran a frontmatter-hygiene + MOC-discipline sprint on 2026-08-10: (a) d97b39ed Phase A 批量 standardized 6 deep-read notes with the 6-field frontmatter (doi / journal / year / volume / pages / authors array / pmid) — Organoids 2026 review + CelVivo PAH Metabolomics + Shin 2024 thalamocortical organoids 22q11ds + Fernandez Vallone 2026 Cells THSDC + Liu 2026 NBME shape-conformal organoid + 类器官综述_CMOS_HD_MEA_类器官电生理_2026-06-05; (b) 6b717aef MOC 方案 1 样品 created the first MOC at 04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md (95 lines, 沙牛《AI 时代的 Obsidian 公开课》课时 1 pattern, type: moc) and added related: back-link frontmatter to 7 papers; (c) 3b929c2f wang2024 方案 2 样品 added 7 image alt descriptions on top of the 6-field frontmatter for wang2024-org-on-chip.md. The MOC's own related: list already names [[MOC-3Brain-HD-MEA]] as the next planned MOC, plus [[02-Clients/Agents/_known_associations]] and [[02-Active-Deals/CellShot-TriArm-Demo-计划-v2-老师版-2026-07-20]], so the pattern is expected to extend. None of the changes add new external evidence — the 6 papers already existed on main; this commit set only normalizes their metadata and cross-references. The MOC creation is the first durable structural artifact on the knowledge-graph side and is worth tracking on the next git-repo fetch.

Synthesis policy for this source

• This run (2026-08-26, git-repo-1 18:06Z): 0 new vault commits in the 2026-08-25T18:13Z → 2026-08-26T18:06Z 24-hour window — vault HEAD unchanged at 9d4767c7 (same as the 2026-08-25T18:13Z fetch); vault silent for the 1st consecutive fetch since the 2026-08-24/25 SECOND 5-paper burst, 1 calendar day stale. No new external evidence in this run. The 2026-08-24/25 cluster remains the most recent committed vault activity (Tevonian + Yang + Shen + Zhai + the 9aa2af4c retrofit). The carry-forward untracked-file set bumps: Review/zhou2023_computer_vision_microfluidics.md 14-day → 15-day carry-forward (12 → 13 fetches silent, structural signal continuing to weaken — subfolder is more likely one-off than recurring) + celvivo_commercial/ + templates/ 9-day → 10-day carry-forward + deepread_40240593/ 2-day → 3-day carry-forward. Wiki-side: 2 new automated wiki commits landed in the 2026-08-25T18:13Z → 2026-08-26T18:06Z 24-hour window — 81ac94a chore: daily update 2026-08-26 (2026-08-26 02:23 +0800; per git show --stat 81ac94a the commit touched 14 files from the prior dirty set including .last-update.json + commitments.md + index.md + quickstart.md + sources/README.md + sources/git-repo.md + sources/hackernews.md + sources/index.md + sources/literature.md + sources/openwiki-version-drift.md + sources/web-search.md + themes.md + themes/index.md + themes/05-robin-research.md; reducing uncommitted-file count from 11 → 8) + ebb95c0 chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-26, 2026-08-26 02:30 +0800, the twelfth consecutive sources-sync re-applying the 2507925 2026-08-15 count-data wipe pattern after 997b648 2026-08-16 + be49285 2026-08-17 + 1fc73ae 2026-08-18 + dcb53a2 2026-08-19 + bd30339 2026-08-20 + f6c2576 2026-08-21 + 43d4548 2026-08-22 + 8f8f767 2026-08-23 + 127c2dc 2026-08-24 + 1003b92 2026-08-25 + now ebb95c0 2026-08-26). The manifest changedFiles shows 8 dirty wiki files this fetch — M .last-update.json + M quickstart.md + M sources/README.md + M sources/hackernews.md + M sources/nocodb.md + M sources/ragflow.md + M sources/seafile.md + M sources/wikijs.md — the same set of synthesis-layer files the very next run will re-touch. Synthesis-layer impact: none — vault delta is empty (no new commits, no new mtime changes) and the wiki delta is automated maintenance only; the synthesis layer (themes / commitments / open-questions / personal-logistics) is independent of the wiki-side automated maintenance commits. No /themes.md row change, no /commitments.md row, no /open-questions.md row, no /personal-logistics.md item at this fetch. Prior run (this section demoted): git-repo-1 2026-08-25T18:13Z.

• Previous run (2026-08-25, git-repo-1 18:13Z): 5 new vault commits in the 2026-08-24T18:05Z → 2026-08-25T18:13Z 24-hour window — the vault HEAD bumped from fb017e4f (2026-08-24T18:05Z fetch) to 9d4767c7 (2026-08-25T18:13Z fetch) — SECOND consecutive single-day 5-paper LDR burst at vault HEAD. Combined with the 2026-08-23/24 5-paper burst, 10 LDR files in 48 hours, the largest sustained 2-day research output in Robin's vault activity log. The 2026-08-25 cluster returns to the per-vendor / per-application-domain subfolder discipline (Tevonian → Vascularized-Organoids/ + Shen → Vascularized-Organoids/ + Yang → Cardiac-Organoids/ + Zhai → Skin-Organoids/), creating 3 NEW subfolders in 04-Literature/Deep-Reads/ (one less than the 5 papers, because Tevonian + Shen share the Vascularized-Organoids/ subfolder). The 5 commits are (a) 089177a7 Tevonian 2026 Nat Commun 血管化肝 MPS deep read (PMID 41634021) — first vascularized liver MPS paper + first file in the new Vascularized-Organoids/ subfolder; (b) 583859a8 Yang 2026 Stem Cell Res Ther cardiac organoid review (PMID 41963991) — first comprehensive cardiac organoid review + first file in the new Cardiac-Organoids/ subfolder; (c) 9aa2af4c post-publish vendor-mapping retrofit commit on Tevonian + Yang files — FIRST post-publish vendor-mapping retrofit in Robin's LDR pipeline (adds CelVivo / Cellink / Mimetas / 3Brain / Femtobiomed 5-vendor mapping + 净化 Robin mentions); (d) 5907cdfc Shen 2026 Chin Med J vascularized organoids review (PMID 42268296) — Chinese-language peer-reviewed vascularized organoid systematic review + second file in the new Vascularized-Organoids/ subfolder; (e) 9d4767c7 Zhai 2026 Sci Adv 3D skin pemphigus (PMID 41512055) — first 3D skin organoid disease-modeling paper + first file in the new Skin-Organoids/ subfolder (NEW application domain — autoimmune dermatology + 3D skin). The 2026-08-24/25 cluster differs from the prior 2026-08-23/24 cluster in three ways: (i) all 5 files landed in per-application-domain subfolders rather than at the 04-Literature/Deep-Reads/ root (return to standard subfolder discipline after the 2026-08-23/24 root-level non-standard pattern); (ii) the cluster includes a non-paper-content retrofit commit (9aa2af4c) which reflects a new SOP step not present in the prior 8 铁律 + 3 trigger modes pattern; (iii) the cluster's application-domain coverage expands into autoimmune dermatology (Zhai skin) which is the first new application-domain subfolder Robin has opened since the 2026-08-13 Review subfolder was added (and even then, Review is type-based, not application-domain-based). Vendor anchor mapping via the 9aa2af4c retrofit: 5-vendor product mapping applied retroactively to Tevonian + Yang; the prior 5-paper 2026-08-23/24 cluster (Ajongbolo + Kim + Tian + Aiello + CelVivo App Note) did NOT receive retroactive retrofit — Tevonian

  • Yang are the first LDR files to use the new post-publish vendor-mapping step. Net-new external evidence in this run (4 paper deep-reads + 1 retrofit commit) — CelVivo/Cellink/Mimetas/3Brain/Femtobiomed product mapping table is the net-new contribution. Wiki-side: 2 new automated wiki commits landed in the 2026-08-24T18:05Z → 2026-08-25T18:13Z 24-hour window — 3255613 chore: daily update 2026-08-25 (2026-08-25 02:23 +0800; per git show --stat 3255613 the commit touched 17 files including commitments.md + sources/git-repo.md + sources/hackernews.md + sources/index.md + sources/literature.md + sources/nocodb.md + sources/openwiki-version-drift.md + sources/ragflow.md + sources/seafile.md + sources/web-search.md + sources/wikijs.md + index.md + quickstart.md + sources/README.md
  • themes.md + themes/05-robin-research.md + themes/index.md) + 1003b92 chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-25, 2026-08-25 02:30 +0800 — the eleventh consecutive sources-sync re-applying the 2507925 2026-08-15 count-data wipe pattern after 997b648 2026-08-16 + be49285 2026-08-17 + 1fc73ae 2026-08-18 + dcb53a2 2026-08-19 + bd30339 2026-08-20 + f6c2576 2026-08-21 + 43d4548 2026-08-22 + 8f8f767 2026-08-23 + 127c2dc 2026-08-24 + now 1003b92 2026-08-25). Both commits are routine auto-orchestration: (a) the 3255613 daily update carried the synthesis-layer edits from the prior HN-1 2026-08-25T18:00Z + web-search-1 2026-08-25 (skipped) + git-repo-1 2026-08-24T18:05Z runs; the 3255613 daily update committed 17 of the prior dirty files; (b) the 1003b92 sources-sync re-applied the count-data wipe pattern on NocoDB / SeaFile / Wiki.js / RAGFlow for the eleventh consecutive sources-sync. The manifest changedFiles shows 11 dirty wiki files this fetch — M .last-update.json + M index.md + M quickstart.md + M sources/README.md + M sources/git-repo.md + M sources/hackernews.md
  • M sources/literature.md + M sources/nocodb.md + M sources/ragflow.md
  • M sources/seafile.md + M sources/web-search.md + M sources/wikijs.md. Net-new external evidence in this run: 4 new paper deep-reads (1 vascularized liver MPS primary research + 1 cardiac organoid review + 1 vascularized organoid Chinese-language review + 1 3D skin pemphigus primary research) + 1 vendor-mapping retrofit commit. New commitments added on /commitments.md: (a) tevonian-2026-vascularized-liver-mps-positioning (Mimetas OrganoPlate + CelVivo ClinoReactor + Cellink BIO X vendor mapping for vascularized liver MPS); (b) yang-2026-cardiac-organoid-review-positioning (canonical cardiac organoid review that contextualizes the Tian 2025 epicardium mTOR deep-read); (c) shen-2026-vascularized-organoid-chinese-review (Chinese-language peer-reviewed systematic review for Chinese-hospital IRB positioning); (d) zhai-2026-skin-organoid-pemphigus-positioning (first autoimmune dermatology + 3D skin entry, candidate workflow for CelVivo ClinoReactor long-term 3D skin culture). New themes-row refresh candidate for /themes.md class-organoid-3d-bioprinting: the 2026-08-24/25 5-paper cluster is the SECOND consecutive single-day 5-paper burst in 48 hours, the 2-day burst is the largest sustained 2-day research output in Robin's vault activity log, and the new application-domain subfolders (Vascularized-Organoids + Cardiac-Organoids + Skin-Organoids) materially expand the per-application-domain subfolder taxonomy. The class-organoid-3d-bioprinting row's evidence footprint is materially strengthened even with no formal row-level Last-seen refresh. Wiki edits this run: (a) /sources/git-repo.md (this page) — refreshed frontmatter HEAD pointers (vault HEAD fb017e4f → 9d4767c7, wiki HEAD 127c2dc → 1003b92, tags + 2026-08-25, timestamp → 2026-08-25T18:13:00Z), refreshed the Connector / State section to the new 2026-08-25T18-13-42-494Z raw manifest, refreshed the obsidian-vault working-tree-status section to 2026-08-25 (5 new vault commits, Review/ 13-day → 14-day carry-forward + templates/ + celvivo_commercial/ 8-day → 9-day carry-forward + deepread_40240593/ 1-day → 2-day carry-forward), refreshed the openwiki-wiki working-tree-status section to 2026-08-25 (2 new automated wiki commits + 11 uncommitted synthesis- layer edits per the manifest changedFiles list — +3 vs the 8-dirty-file baseline at the 2026-08-24 fetch because the 3255613 daily update added 3 newly dirty files: index.md + quickstart.md + sources/git-repo.md vs the 2026-08-24 prior baseline), added 5 new entries at the top of the Recent-commits-for-vault table (9d4767c7 Zhai + 5907cdfc Shen + 9aa2af4c vendor-mapping retrofit + 583859a8 Yang + 089177a7 Tevonian), added 2 new entries at the top of the Recent-commits-for-wiki table (1003b92 sources-sync 2026-08-25 + 3255613 daily update 2026-08-25), refreshed the Summary-of-last-48-hours table to add the 2026-08-24T18:05Z → 2026-08-25T18:13Z window data (5 vault commits / 2 wiki commits / operational row noting the eleventh consecutive sources-sync re-applying the count-data wipe pattern + the SECOND 5-paper LDR burst detail), refreshed the 04-Literature/Deep-Reads/ breakdown table (added 3 new subfolders Vascularized-Organoids/ + Cardiac-Organoids/
  • Skin-Organoids/ + bumped total 1,212 → 1,217 + Review/ 13-day → 14-day + celvivo_commercial/ + templates/ 8-day → 9-day carry-forward), added 7 new entries to the Notable-entity section (the 2026-08-24/25 cluster overview + 4 individual paper entries + 9aa2af4c retrofit pattern entry + Review/ 13 → 14-day carry-forward bump); refreshed the Synthesis-policy section with this run's delta summary (the old 2026-08-24 "This run" was demoted to "Previous run" and the new "This run" reflects the 2026-08-24/25 SECOND consecutive 5-paper LDR burst); (b) /themes/05-robin-research.md — vault-snapshot metadata refreshed (fetch timestamp → 2026-08-25T18:13:00Z, raw-manifest path → the new 2026-08-25T18-13-42-494Z manifest, HEAD bumped fb017e4f → 9d4767c7, the SECOND 5-paper LDR burst noted in the cluster section + 3 new subfolders + the 9aa2af4c retrofit pattern); (c) /commitments.md — added 4 new commitment entries corresponding to the 4 new LDR papers (each with Owner: me + Source: git-repo-1 2026-08-25 + Status: open); (d) /sources/literature.md — added 4 new rows to the "Last 30 days of deep reads" table under a new 2026-08-25 subsection; (e) /quickstart.md — added this "Latest update — git-repo-1 (2026-08-25T18:13Z)" paragraph; updated the Backlog git-repo entry to reflect the new wiki HEAD 1003b92 + 2 new automated wiki commits + the carry-forward 11 uncommitted synthesis-layer edits + the eleventh consecutive sources-sync note + the SECOND 5-paper LDR burst detail; (f) /sources/README.md — refreshed Active connectors Git repo row + Connector roll Git repo row to mention the 2026-08-25 18:13 UTC fetch + the eleventh consecutive sources-sync + the 5 new vault commits + the 3 new subfolders. No new /themes.md row added — the existing class-organoid-3d-bioprinting row's evidence footprint is materially strengthened (10 papers in 48 hours, 3 new application-domain subfolders) but the theme row already covers the same general topic; per scope discipline, theme-row additions require a topic-key that doesn't already exist; (the recurrent nature of the LDR burst — 2 consecutive 5-paper clusters in 48 hours — is the strongest evidence to date that Robin has entered a "research-sprint mode" that might justify a future robin-research-sprint-2026-08-23-25 watchlist row, but such a row would be too transient for the durable /themes.md index). No /open-questions.md row added — none of the 4 new LDR papers surfaces a new memory/wiki gap; the existing 5 active open questions (agent-dong-huiqun-celvivo / liu-2026-rogers-lab-vs-3brain-relationship / chengdu-baile-vs-lidesai-for-ou-xianhong / distributors-3brain-cellink- zero-coverage / sharma-2026-retinal-organoid-mea-cross-sell) carry forward unchanged. No /personal-logistics.md item — the vault delta is work-side only.

• This run (2026-08-24, git-repo-1 18:05Z): 5 new vault commits Cells brain organoid review (Wiki.js 1743); (b) 5f02489a Kim 2025 Nat Commun EGaIn liquid-metal 3D MEA (Wiki.js 1744); (c) 40b357b8 Tian 2025 Nat Commun hiPSC epicardium mTOR maturation (Wiki.js 1745); (d) f2118a62 Aiello & Bagni 2025 biorxiv Rotating Chamber brain organoid CFD (Wiki.js 1746, CelVivo KB-derived); (e) fb017e4f CelVivo App Note 2026 shear stress ClinoStar vs orbital shaker (Wiki.js 1747). All 5 files landed at obsidian-vault/04-Literature/Deep-Reads/ root (not in a per-vendor subfolder — non-standard pattern, see Notable-entity § "2026-08-23 root-level LDR burst"). Vendor-anchor mapping: 3 CelVivo-aligned (App Note + Aiello + Ajongbolo review) + 1 3Brain-adjacent (Kim EGaIn 3D MEA) + 1 cardiac epicardium (Tian mTOR, no vendor callouts). 1 new untracked directory appeared in the working tree this fetch — deepread_40240593/ (7 subdirs: 5 PMID-named + 2 slug-named that exactly map to the Aiello + CelVivo App Note papers; the new directory is Robin's LDR pipeline intermediate-artifact workspace, see Notable-entity). The 2 prior untracked directories (celvivo_commercial/ + templates/) and the Review/zhou2023_computer_vision_microfluidics.md first-entry-in-Review/-subfolder carry forward unchanged from the prior fetch (now 8-day carry-forward for celvivo_commercial/ + templates/; 13-day carry-forward + 11 fetches silent for the Review/ file). Wiki-side: 2 new automated wiki commits landed in the 24-hour window — 9cc5e63 chore: daily update 2026-08-24 (2026-08-24 02:23 +0800) + 127c2dc chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-24, 2026-08-24 02:30 +0800) — advancing wiki HEAD from a9568d8 (2026-08-23T18:11Z fetch) to 127c2dc. Both commits are routine auto-orchestration: (a) the 9cc5e63 daily update carried the synthesis-layer edits from the prior HN-1 2026-08-23T18:00Z + web-search-1 2026-08-23 (skipped) + git-repo-1 2026-08-23T18:11Z runs; the 9cc5e63 daily update committed sources/git-repo.md + sources/hackernews.md + sources/index.md + sources/openwiki-version-drift.md + sources/web-search.md + themes/05-robin-research.md from the 2026-08-23 dirty set; (b) the 127c2dc sources-sync re-applied the count-data wipe pattern on NocoDB / SeaFile / Wiki.js / RAGFlow for the tenth consecutive sources-sync (after 2026-08-15 2507925 + 2026-08-16 997b648 + 2026-08-17 be49285 + 2026-08-18 1fc73ae + 2026-08-19 dcb53a2 + 2026-08-20 bd30339 + 2026-08-21 f6c2576 + 2026-08-22 43d4548 + 2026-08-23 8f8f767). Net-new external evidence in this run: 5 new paper deep-reads (1 vendor App Note + 4 primary research papers / 1 review / 1 preprint) — all committed to main. Net-new working-tree artifact: deepread_40240593/ pipeline-workspace directory (1 new untracked dir). New commitments added on /commitments.md: (a) celvivo-app-note-2026-clinostar-vs-orbital-shaker-positioning (fold the head-to-head shear-stress comparison into the ClinoStar sales narrative + into the existing CelVivo赋能培训 cluster); (b) aiello-2025-rc-cfd-clinostar-positioning (the < 20 mPa quantitative number is direct ClinoStar value-prop ammunition); (c) kim-2025-egain-3d-mea-vs-3brain-positioning (next-gen HD-MEA field consolidation: Liu 2026 Rogers Lab + Kim 2025 EGaIn + 3Brain Accura-3D); (d) ajongbolo-2025-brain-organoid-review-cluster (pair with the existing Organoids 2026 review to anchor brain-organoid review lane); (e) tian-2025-epicardium-mtor-cardiac-expansion (first cardiac-epicardium paper in deep-read set; no vendor callouts). New themes-row refresh candidate for /themes.md class-organoid-3d-bioprinting row: the 5-paper burst is the largest single-day cluster since 2026-07-29 + breaks the 7-fetch silence; 3 of the 5 papers directly reference CelVivo ClinoStar or 3Brain, validating the recurring-signal evidence footprint. Track on next fetch whether (a) the deepread_40240593/ directory gets committed (currently untracked, 1-day-old); (b) any of the 5 new LDR files get a wiki-side synthesis page (none currently in /sources/literature-* naming pattern). Wiki edits this run: (a) /sources/git-repo.md (this page) — refreshed frontmatter HEAD pointers (vault HEAD a4fa5a32 → fb017e4f, wiki HEAD a9568d8 → 127c2dc, tags + 2026-08-24, timestamp → 2026-08-24T18:05:00Z), refreshed the Connector / State section to the new 2026-08-24T18-05-31-919Z raw manifest, refreshed the obsidian-vault working-tree-status section to 2026-08-24 (5 new vault commits, 1 new untracked dir deepread_40240593/, celvivo_commercial/ + templates/ 7-day → 8-day carry-forward, Review/ 12-day → 13-day + 10 fetches silent → 11 fetches silent), refreshed the openwiki-wiki working-tree-status section to 2026-08-24 (2 new automated wiki commits + 8 uncommitted synthesis-layer edits per the manifest changedFiles list), added 2 new entries at the top of the Recent-commits-for-vault table (5 new vault commits) + 2 new entries at the top of the Recent-commits-for-wiki table (127c2dc sources-sync 2026-08-24

  • 9cc5e63 daily update 2026-08-24), refreshed the Summary-of-last-48-hours table to add the 2026-08-23T18:11Z → 2026-08-24T18:05Z window data (5 vault commits / 2 wiki commits / operational row noting the tenth consecutive sources-sync re-applying the count-data wipe pattern
  • the 5-paper LDR burst detail), refreshed the 04-Literature/Deep-Reads/ breakdown table (added the root-level 5-file entry + bumped Review/ 12 → 13-day + celvivo_commercial/ + templates/ 7 → 8-day carry-forward + total 1,207 → 1,212), added 7 new entries to the Notable-entity section (the 2026-08-23 root-level LDR burst overview + 5 individual paper entries + the deepread_40240593/ pipeline workspace entry), refreshed the Synthesis-policy section with this run's delta summary (the old 2026-08-23 "This run" was demoted to "Previous run (2026-08-23, git-repo-1 18:11Z)" and the new "This run" reflects the 5-paper LDR burst); (b) /themes/05-robin-research.md — vault-snapshot metadata refreshed (fetch timestamp → 2026-08-24T18:05:00Z, raw-manifest path → the new 2026-08-24T18-05-31-919Z manifest, HEAD bumped a4fa5a32 → fb017e4f, the 5-paper LDR burst noted in the cluster section, the 04-Literature/Deep-Reads/ breakdown table updated with the root-level 5-file entry + total 1,207 → 1,212, celvivo_commercial/ + templates/ 7-day → 8-day carry-forward + Review/ 12-day → 13-day + 10 fetches silent → 11 fetches silent); (c) /commitments.md — added 5 new commitment entries corresponding to the 5 new LDR papers (each with Owner: me + Source: git-repo-1 2026-08-24 + Status: open); (d) /sources/literature.md — added 5 new rows to the "Last 30 days of deep reads" table under a new 2026-08-23 subsection; (e) /quickstart.md — added this "Latest update — git-repo-1 (2026-08-24T18:05Z)" paragraph; updated the Backlog git-repo entry to reflect the new wiki HEAD 127c2dc + 2 new automated wiki commits + the carry-forward 8 uncommitted synthesis-layer edits
  • the tenth consecutive sources-sync note + the 5-paper LDR burst detail; (f) /sources/README.md — refreshed Active connectors Git repo row + Connector roll Git repo row to mention the 2026-08-24 18:05 UTC fetch + the tenth consecutive sources-sync. No /themes.md row change — the 5-paper LDR burst strengthens the existing class-organoid-3d-bioprinting evidence footprint (3 of 5 papers vendor-aligned to CelVivo + 3Brain) but does not warrant a new theme row at this fetch (single-day burst, no recurrence yet); if a 2026-08-25 fetch surfaces another deep-read cluster, that becomes the recurrence trigger for a theme-row promotion.

• Previous run (2026-08-23, git-repo-1 18:11Z): 0 new vault commits in the 2026-08-22T18:13Z → 2026-08-23T18:11Z 24-hour window — the vault HEAD is unchanged at a4fa5a32 for the 7th consecutive fetch (the 2026-08-16 Quintard 2024 Nat Commun 4-commit LDR cycle

  • Guo 2026 Front Cell Dev Biol 3-commit LDR cycle remain the most recent vault activity, 7 calendar days stale at this fetch). 0 new vault mtime changes — the 2 untracked directories (celvivo_commercial/ + templates/) and the 23+ untracked files from the 2026-08-17T18:09Z fetch carry forward unchanged. The Review/zhou2023_computer_vision_microfluidics.md first-entry in the new Review/ subfolder is 12-day carry-forward at this fetch (uncommitted since 2026-08-11); the structural signal for Review/ continues to weaken per the Notable-entity entry (the subfolder has been a single-entry watchlist since 2026-08-13, now 10 fetches silent). Wiki-side: 2 new automated wiki commits landed in the 24-hour window — 8f8f767 chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-23, 2026-08-23 02:30 +0800) + a9568d8 chore: daily update 2026-08-23 (2026-08-23 02:29 +0800) — advancing wiki HEAD from 43d4548 (2026-08-22T18:13Z fetch) to a9568d8. Both commits are routine auto-orchestration: (a) the a9568d8 daily update carried the synthesis-layer edits from the prior HN-1 2026-08-22T18:00Z + web-search-1 2026-08-22 (skipped) + web-search-1 2026-08-23 (skipped) + git-repo-1 2026-08-22T18:13Z runs; the a9568d8 daily update committed sources/git-repo.md + sources/index.md + sources/nocodb.md + sources/ragflow.md + sources/seafile.md
  • sources/wikijs.md + themes/05-robin-research.md from the 2026-08-22 dirty set, reducing the uncommitted-file count from 9 → 6; (b) the 8f8f767 sources-sync re-applied the count-data wipe pattern on NocoDB / SeaFile / Wiki.js / RAGFlow for the ninth consecutive sources-sync (after 2026-08-15 2507925 + 2026-08-16 997b648 + 2026-08-17 be49285 + 2026-08-18 1fc73ae + 2026-08-19 dcb53a2 + 2026-08-20 bd30339 + 2026-08-21 f6c2576 + 2026-08-22 43d4548). No new external evidence in this run (vault silent), no new theme row, no new commitment row, no new open-question row, no new personal-logistics item — the synthesis layer is unchanged. Wiki edits this run: (a) /sources/git-repo.md (this page) — refreshed frontmatter HEAD pointers (vault HEAD unchanged at a4fa5a32, wiki HEAD 43d4548 → a9568d8, tags + 2026-08-23, timestamp → 2026-08-23T18:11:00Z), refreshed the Connector / State section to the new 2026-08-23T18-11-34-883Z raw manifest, refreshed the obsidian-vault working-tree-status section to 2026-08-23 (0 new commits, 0 new mtime changes, untracked set unchanged; Review/ 11-day → 12-day + templates/ + celvivo_commercial/ 6-day → 7-day carry-forward), refreshed the openwiki-wiki working-tree-status section to 2026-08-23 (2 new automated wiki commits + 6 uncommitted synthesis-layer edits, down from 9 at the 2026-08-22T18:13Z fetch because a9568d8 committed 7 of the prior 9 dirty files), added 2 new entries at the top of the Recent-commits-for-wiki table (a9568d8 daily update 2026-08-23 + 8f8f767 sources-sync 2026-08-23), refreshed the Summary-of-last-48-hours table to add the 2026-08-22T18:13Z → 2026-08-23T18:11Z window data (0 vault commits / 2 wiki commits / operational row noting the ninth consecutive sources-sync re-applying the count-data wipe pattern), refreshed the Notable-entity Review/ entry (11-day → 12-day carry- forward, 9 fetches silent → 10 fetches silent) + bumped templates/ + celvivo_commercial/ 6-day → 7-day + refreshed the 04-Literature/Deep-Reads/ breakdown table, refreshed the Synthesis-policy section with this run's delta summary; (b) /themes/05-robin-research.md — vault-snapshot metadata refreshed (fetch timestamp → 2026-08-23T18:11:00Z, raw-manifest path → the new 2026-08-23T18-11-34-883Z manifest); the vault HEAD pointer stays a4fa5a32 (unchanged across the 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 fetches); Review/ 11-day → 12-day carry-forward; Templates/ + CelVivo-commercial/ 6-day → 7-day; (c) /quickstart.md — added the "Latest update — git-repo-1 (2026-08-23T18:11Z)" paragraph; updated the Backlog git-repo entry to reflect the new wiki HEAD a9568d8 + 2 new automated wiki commits + 6 uncommitted synthesis-layer edits (down from 9 at the prior fetch because a9568d8 committed 7 of the prior 9 dirty files) + the ninth consecutive sources-sync note; (d) /sources/README.md — refreshed Active connectors Git repo row + Connector roll Git repo row to mention the 2026-08-23 18:11 UTC fetch + the ninth consecutive sources-sync. No /themes.md row change, no /commitments.md row, no /open-questions.md row, no /personal-logistics.md item — the vault delta is empty and the wiki delta is automated maintenance only. The "vault is silent on a 24-hour window" pattern continues to be normal cadence for Robin's workflow (the 2026-08-13 + 2026-08-15 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 fetches were also 0-new-vault-commits daily-cycle follow-ups; the 2026-08-23 fetch makes it 8 consecutive 0-new-vault-commit fetches). The synthesis layer (themes / commitments / open-questions / personal-logistics) is independent of the wiki-side automated maintenance commits.

• Previous run (2026-08-22, git-repo-1 18:13Z): 0 new vault commits in the 2026-08-21T18:09Z → 2026-08-22T18:13Z 24-hour window — the vault HEAD is unchanged at a4fa5a32 for the 6th consecutive fetch (the 2026-08-16 Quintard 2024 Nat Commun 4-commit LDR cycle

  • Guo 2026 Front Cell Dev Biol 3-commit LDR cycle remain the most recent vault activity, 6 calendar days stale at this fetch). 0 new vault mtime changes — the 2 untracked directories (celvivo_commercial/ + templates/) and the 23+ untracked files from the 2026-08-17T18:09Z fetch carry forward unchanged. The Review/zhou2023_computer_vision_microfluidics.md first-entry in the new Review/ subfolder is 11-day carry-forward at this fetch (uncommitted since 2026-08-11); the structural signal for Review/ continues to weaken per the Notable-entity entry (the subfolder has been a single-entry watchlist since 2026-08-13, now 9 fetches silent). Wiki-side: 2 new automated wiki commits landed in the 24-hour window — d8e2277 chore: daily update 2026-08-22 (2026-08-22 02:23 +0800) + 43d4548 chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-22, 2026-08-22 02:30 +0800) — advancing wiki HEAD from f6c2576 (2026-08-21T18:09Z fetch) to 43d4548. Both commits are routine auto-orchestration: (a) the d8e2277 daily update carried the synthesis-layer edits from the prior HN-1 2026-08-22T18:00Z + web-search-1 2026-08-22 (skipped) + git-repo-1 2026-08-21T18:09Z runs; (b) the 43d4548 sources-sync re-applied the count-data wipe pattern on NocoDB / SeaFile / Wiki.js / RAGFlow for the eighth consecutive sources-sync (after 2026-08-15 2507925 + 2026-08-16 997b648 + 2026-08-17 be49285 + 2026-08-18 1fc73ae + 2026-08-19 dcb53a2 + 2026-08-20 bd30339 + 2026-08-21 f6c2576). No new external evidence in this run (vault silent), no new theme row, no new commitment row, no new open-question row, no new personal-logistics item — the synthesis layer is unchanged. Wiki edits this run: (a) /sources/git-repo.md (this page) — refreshed frontmatter HEAD pointers (vault HEAD unchanged at a4fa5a32, wiki HEAD f6c2576 → 43d4548, tags + 2026-08-22, timestamp → 2026-08-22T18:13:00Z), refreshed the Connector / State section to the new 2026-08-22T18-13-00-193Z raw manifest, refreshed the obsidian-vault working-tree-status section to 2026-08-22 (0 new commits, 0 new mtime changes, untracked set unchanged; Review/ 10-day → 11-day + templates/ + celvivo_commercial/ 5-day → 6-day carry-forward), refreshed the openwiki-wiki working-tree-status section to 2026-08-22 (2 new automated wiki commits + 9 uncommitted synthesis-layer edits, the same dirty count as the 2026-08-21T18:09Z fetch), added 2 new entries at the top of the Recent-commits-for-wiki table (43d4548 sources-sync 2026-08-22 + d8e2277 daily update 2026-08-22), refreshed the Summary-of-last-48-hours table to add the 2026-08-21T18:09Z → 2026-08-22T18:13Z window data (0 vault commits / 2 wiki commits / operational row noting the eighth consecutive sources-sync re-applying the count-data wipe pattern), refreshed the Notable-entity Review/ entry (10-day → 11-day carry- forward, 8 fetches silent → 9 fetches silent) + bumped templates/ + celvivo_commercial/ 5-day → 6-day, refreshed the Synthesis-policy section with this run's delta summary; (b) /themes/05-robin-research.md — vault-snapshot metadata refreshed (fetch timestamp → 2026-08-22T18:13:00Z, raw-manifest path → the new 2026-08-22T18-13-00-193Z manifest); the vault HEAD pointer stays a4fa5a32 (unchanged across the 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 fetches); Review/ 10-day → 11-day carry-forward; Templates/ + CelVivo-commercial/ 5-day → 6-day; (c) /quickstart.md — added the "Latest update — git-repo-1 (2026-08-22T18:13Z)" paragraph; updated the Backlog git-repo entry to reflect the new wiki HEAD 43d4548 + 2 new automated wiki commits + 9 uncommitted synthesis-layer edits (same count as prior fetch) + the eighth consecutive sources-sync note; (d) /sources/README.md — refreshed Active connectors Git repo row + Connector roll Git repo row to mention the 2026-08-22 18:13 UTC fetch + the eighth consecutive sources-sync. No /themes.md row change, no /commitments.md row, no /open-questions.md row, no /personal-logistics.md item — the vault delta is empty and the wiki delta is automated maintenance only. The "vault is silent on a 24-hour window" pattern continues to be normal cadence for Robin's workflow (the 2026-08-13 + 2026-08-15 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 fetches were also 0-new-vault-commits daily-cycle follow-ups; the 2026-08-22 fetch makes it 7 consecutive 0-new-vault-commit fetches). The synthesis layer (themes / commitments / open-questions / personal-logistics) is independent of the wiki-side automated maintenance commits.

• Previous run (2026-08-21, git-repo-1 18:09Z): 0 new vault commits in the 2026-08-20T18:09Z → 2026-08-21T18:09Z 24-hour window — the vault HEAD is unchanged at a4fa5a32 for the 5th consecutive fetch (the 2026-08-16 Quintard 2024 Nat Commun 4-commit LDR cycle

  • Guo 2026 Front Cell Dev Biol 3-commit LDR cycle remain the most recent vault activity, 5 calendar days stale at this fetch). 0 new vault mtime changes — the 2 untracked directories (celvivo_commercial/ + templates/) and the 23+ untracked files from the 2026-08-17T18:09Z fetch carry forward unchanged. The Review/zhou2023_computer_vision_microfluidics.md first-entry in the new Review/ subfolder is 10-day carry-forward at this fetch (uncommitted since 2026-08-11); the structural signal for Review/ continues to weaken per the Notable-entity entry (the subfolder has been a single-entry watchlist since 2026-08-13, now 8 fetches silent). Wiki-side: 2 new automated wiki commits landed in the 24-hour window — b6dc337 chore: daily update 2026-08-21 (2026-08-21 02:27 +0800) + f6c2576 chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-21, 2026-08-21 02:30 +0800) — advancing wiki HEAD from bd30339 (2026-08-20T18:09Z fetch) to f6c2576. Both commits are routine auto-orchestration: (a) the b6dc337 daily update carried the synthesis-layer edits from the prior HN-1 2026-08-21T18:00Z + web-search-1 2026-08-21 (skipped) + git-repo-1 2026-08-20T18:09Z runs; the b6dc337 daily update committed sources/index.md from the 2026-08-20 dirty set (reducing uncommitted-file count from 10 → 9 at this fetch); (b) the f6c2576 sources-sync re-applied the count-data wipe pattern on NocoDB / SeaFile / Wiki.js / RAGFlow for the seventh consecutive sources-sync (after 2026-08-15 2507925 + 2026-08-16 997b648 + 2026-08-17 be49285 + 2026-08-18 1fc73ae + 2026-08-19 dcb53a2 + 2026-08-20 bd30339). No new external evidence in this run (vault silent), no new theme row, no new commitment row, no new open-question row, no new personal-logistics item — the synthesis layer is unchanged. Wiki edits this run: (a) /sources/git-repo.md (this page) — refreshed frontmatter HEAD pointers (vault HEAD unchanged at a4fa5a32, wiki HEAD dcb53a2 → bd30339, tags + 2026-08-20, timestamp → 2026-08-20T18:09:15Z), refreshed the Connector / State section to the new 2026-08-20T18-09-15-122Z raw manifest, refreshed the obsidian-vault working-tree-status section to 2026-08-20 (0 new commits, 0 new mtime changes, untracked set unchanged; Review/ 8-day → 9-day + templates/ + celvivo_commercial/ 3-day → 4-day carry-forward), refreshed the openwiki-wiki working-tree-status section to 2026-08-20 (2 new automated wiki commits + the carry-forward 10 uncommitted synthesis-layer edits), added 2 new entries at the top of the Recent-commits-for-wiki table (bd30339 sources-sync 2026-08-20 + a44f284 daily update 2026-08-20), refreshed the Summary-of-last-48-hours table to add the 2026-08-19T18:08Z → 2026-08-20T18:09Z window data (0 vault commits / 2 wiki commits / operational row noting the sixth consecutive sources-sync re-applying the count-data wipe pattern), refreshed the Notable-entity Review/ entry (8-day → 9-day carry- forward, 6 fetches silent → 7 fetches silent) + bumped templates/ + celvivo_commercial/ 3-day → 4-day, refreshed the Synthesis-policy section with this run's delta summary; (b) /themes/05-robin-research.md — vault-snapshot metadata refreshed (fetch timestamp → 2026-08-20T18:09:15Z, raw-manifest path → the new 2026-08-20T18-09-15-122Z manifest); the vault HEAD pointer stays a4fa5a32 (unchanged across the 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 fetches); Review/ 8-day → 9-day carry-forward; Templates/ + CelVivo-commercial/ 3-day → 4-day; (c) /quickstart.md — added the "Latest update — git-repo-1 (2026-08-20T18:09Z)" paragraph; updated the Backlog git-repo entry to reflect the new wiki HEAD bd30339 + 2 new automated wiki commits + the carry-forward 10 uncommitted files + the sixth consecutive sources-sync note; (d) /sources/README.md — refreshed Active connectors Git repo row + Connector roll Git repo row to mention the 2026-08-20 18:09 UTC fetch + the sixth consecutive sources-sync. No /themes.md row change, no /commitments.md row, no /open-questions.md row, no /personal-logistics.md item — the vault delta is empty and the wiki delta is automated maintenance only. The "vault is silent on a 24-hour window" pattern continues to be normal cadence for Robin's workflow (the 2026-08-13 + 2026-08-15 + 2026-08-18 + 2026-08-19 fetches were also 0-new-vault-commits daily-cycle follow-ups; the 2026-08-20 fetch makes it 5 consecutive 0-new-vault-commit fetches). The synthesis layer (themes / commitments / open-questions / personal-logistics) is independent of the wiki-side automated maintenance commits.

• Previous run (2026-08-19, git-repo-1 18:08Z): 0 new vault commits in the 2026-08-18T18:10Z → 2026-08-19T18:08Z 24-hour window — the vault HEAD is unchanged at a4fa5a32 for the 3rd consecutive fetch (the 2026-08-16 Quintard 2024 Nat Commun 4-commit LDR cycle

  • Guo 2026 Front Cell Dev Biol 3-commit LDR cycle remain the most recent vault activity, 3 calendar days stale at this fetch). 0 new vault mtime changes — the 2 untracked directories (celvivo_commercial/ + templates/) and the 23+ untracked files from the 2026-08-17T18:09Z fetch carry forward unchanged. The Review/zhou2023_computer_vision_microfluidics.md first-entry in the new Review/ subfolder is 8-day carry-forward at this fetch (uncommitted since 2026-08-11); the structural signal for Review/ continues to weaken per the Notable-entity entry (the subfolder has been a single-entry watchlist since 2026-08-13, now 6 fetches silent). Wiki-side: 2 new automated wiki commits landed in the 24-hour window — 7e904ec chore: daily update 2026-08-19 (2026-08-19 02:23 +0800) + dcb53a2 chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-19, 2026-08-19 02:30 +0800) — advancing wiki HEAD from 1fc73ae (2026-08-18T18:10Z fetch) to dcb53a2. Both commits are routine auto-orchestration: (a) the 7e904ec daily update carried the synthesis-layer edits from the prior HN-1 2026-08-19T18:00Z + web-search-1 2026-08-19 + git-repo-1 2026-08-18T18:10Z runs (touching .last-update.json + quickstart.md + sources/{README,git-repo,hackernews,index,nocodb,ragflow,seafile,web-search,wikijs}.md
  • themes/05-robin-research.md per git show --stat 7e904ec); (b) the dcb53a2 sources-sync re-applied the count-data wipe pattern on NocoDB / SeaFile / Wiki.js / RAGFlow for the fifth consecutive sources-sync (after 2026-08-15 2507925 + 2026-08-16 997b648 + 2026-08-17 be49285 + 2026-08-18 1fc73ae). No new external evidence in this run (vault silent), no new theme row, no new commitment row, no new open-question row, no new personal-logistics item — the synthesis layer is unchanged. Wiki edits this run: (a) /sources/git-repo.md (this page) — refreshed frontmatter HEAD pointers (vault HEAD unchanged at a4fa5a32, wiki HEAD 1fc73ae → dcb53a2, tags + 2026-08-19, timestamp → 2026-08-19T18:08:24Z), refreshed the Connector / State section to the new 2026-08-19T18-08-24-164Z raw manifest, refreshed the obsidian-vault working-tree-status section to 2026-08-19 (0 new commits, 0 new mtime changes, untracked set unchanged), refreshed the openwiki-wiki working-tree-status section to 2026-08-19 (2 new automated wiki commits + the carry-forward 10 uncommitted synthesis-layer edits — sources/index.md re-appears as dirty in the working tree at this fetch), added 2 new entries at the top of the Recent-commits-for-wiki table (dcb53a2 + 7e904ec), refreshed the Summary-of-last-48-hours table to add the 2026-08-18T18:10Z → 2026-08-19T18:08Z window data (0 vault commits / 2 wiki commits / operational row noting the fifth consecutive sources-sync re-applying the count-data wipe pattern), refreshed the Synthesis-policy section with this run's delta summary; (b) /themes/05-robin-research.md — vault-snapshot metadata refreshed (fetch timestamp → 2026-08-19T18:08:24Z, raw-manifest path → the new 2026-08-19T18-08-24-164Z manifest); the vault HEAD pointer stays a4fa5a32 (unchanged across the 2026-08-17 + 2026-08-18 + 2026-08-19 fetches); (c) /quickstart.md — added the "Latest update — git-repo-1 (2026-08-19T18:08Z)" paragraph; updated the Backlog git-repo entry to reflect the new wiki HEAD dcb53a2 + 2 new automated wiki commits + the carry-forward 10 uncommitted files + the fifth consecutive sources-sync note. No /themes.md row change, no /commitments.md row, no /open-questions.md row, no /personal-logistics.md item — the vault delta is empty and the wiki delta is automated maintenance only. The "vault is silent on a 24-hour window" pattern continues to be normal cadence for Robin's workflow (the 2026-08-13 + 2026-08-15 + 2026-08-18 fetches were also 0-new-vault-commits daily-cycle follow-ups; the 2026-08-19 fetch made it 4 consecutive 0-new-vault-commit fetches). The synthesis layer (themes / commitments / open-questions / personal-logistics) is independent of the wiki-side automated maintenance commits.

• Previous run (2026-08-18, git-repo-1 18:10Z): 0 new vault commits in the 2026-08-17T18:09Z → 2026-08-18T18:10Z 24-hour window — the vault HEAD is unchanged at a4fa5a32 (the 2026-08-16 Quintard 2024 Nat Commun 4-commit LDR cycle + Guo 2026 Front Cell Dev Biol 3-commit LDR cycle remain the most recent vault activity, 2 calendar days stale at this fetch). 0 new vault mtime changes — the 2 untracked directories (celvivo_commercial/ + templates/) and the 23+ untracked files from the 2026-08-17T18:09Z fetch carry forward unchanged. The Review/zhou2023_computer_vision_microfluidics.md first-entry in the new Review/ subfolder is 7-day carry-forward at this fetch (uncommitted since 2026-08-11); the structural signal for Review/ continues to weaken per the Notable-entity entry (the subfolder has been a single-entry watchlist since 2026-08-13). Wiki-side: 2 new automated wiki commits landed in the 24-hour window — 8127797 chore: daily update 2026-08-18 (2026-08-18 02:23 +0800) + 1fc73ae chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-18, 2026-08-18 02:30 +0800) — advancing wiki HEAD from be49285 (2026-08-17T18:09Z fetch) to 1fc73ae. Both commits are routine auto-orchestration: (a) the 8127797 daily update carried the synthesis-layer edits from the prior HN-1 2026-08-18T18:00Z run + this git-repo-1 2026-08-17T18:09Z run (touching commitments.md + index.md + quickstart.md + sources/{README,git-repo,hackernews,index,literature,nocodb,ragflow,seafile,web-search,wikijs}.md

  • themes/{01-organoid-equipment,05-robin-research}.md per git show --stat 8127797); (b) the 1fc73ae sources-sync re-applied the count-data wipe pattern on NocoDB / SeaFile / Wiki.js / RAGFlow for the fourth consecutive sources-sync (after 2026-08-15 2507925 + 2026-08-16 997b648 + 2026-08-17 be49285). No new external evidence in this run (vault silent), no new theme row, no new commitment row, no new open-question row, no new personal-logistics item — the synthesis layer is unchanged. Wiki edits this run: (a) /sources/git-repo.md (this page) — refreshed frontmatter HEAD pointers (vault HEAD unchanged at a4fa5a32, wiki HEAD be49285 → 1fc73ae, tags + 2026-08-18, timestamp → 2026-08-18T18:10:12Z), refreshed the Connector / State section to the new 2026-08-18T18-10-12-916Z raw manifest, refreshed the obsidian-vault working-tree-status section to 2026-08-18 (0 new commits, 0 new mtime changes, untracked set unchanged), refreshed the openwiki-wiki working-tree-status section to 2026-08-18 (2 new automated wiki commits + the carry-forward 9 uncommitted synthesis-layer edits), added 2 new entries at the top of the Recent-commits-for-wiki table (1fc73ae + 8127797), refreshed the Summary-of-last-48-hours table to add the 2026-08-17T18:09Z → 2026-08-18T18:10Z window data (0 vault commits / 2 wiki commits / operational row noting the fourth consecutive sources-sync re-applying the count-data wipe pattern), refreshed the Synthesis-policy section with this run's delta summary; (b) /themes/05-robin-research.md — vault-snapshot metadata refreshed (fetch timestamp → 2026-08-18T18:10:12Z, raw-manifest path → the new 2026-08-18T18-10-12-916Z manifest); the vault HEAD pointer stays a4fa5a32 (unchanged across both 2026-08-17 and 2026-08-18 fetches); (c) /quickstart.md — added the "Latest update — git-repo-1 (2026-08-18T18:10Z)" paragraph; updated the Backlog git-repo entry to reflect the new wiki HEAD 1fc73ae + 2 new automated wiki commits + the carry-forward 9 uncommitted files + the fourth consecutive sources-sync note. No /themes.md row change, no /commitments.md row, no /open-questions.md row, no /personal-logistics.md item — the vault delta is empty and the wiki delta is automated maintenance only. The "vault is silent on a 24-hour window" pattern continues to be normal cadence for Robin's workflow (the 2026-08-13 fetch was also a 0-new-vault-commits daily-cycle follow-up; the 2026-08-15 fetch was also a 0-new-vault- commits daily-cycle follow-up). The synthesis layer (themes / commitments / open-questions / personal-logistics) is independent of the wiki-side automated maintenance commits.

• Previous run (2026-08-17, git-repo-1 18:09Z): 7 new vault commits landed in the 2026-08-15T18:07Z → 2026-08-17T18:09Z window — the vault HEAD bumped from 297f106d (the 2026-08-12 Liang 2026 cluster) to a4fa5a32 (the 2026-08-16 Quintard 2024 + Guo 2026 cluster). The cluster breaks down as: (a) Quintard 2024 Nat Commun 4-commit LDR cycle (0fc8db24 adds 189 lines → 290e9635 -v2 修图床/双 H1/落款 → 24c713de -v3 Wiki.js 自带图床 6 张图 → 4073abf4 -v4 转发语标题/ 落款加粗/删 3Brain) on obsidian-vault/Literature/Deep-Reads/Organoid/quintard_2024_vasorganoid_chip.md; (b) Guo 2026 Front Cell Dev Biol 3-commit LDR cycle (2e6f5989 adds 170 lines → 00f824f2 -v2 修图床 (加 2 张 Wiki.js 自带图) → a4fa5a32 -v3 补 Fig 1) on obsidian-vault/Literature/Deep-Reads/Organoid/guo_2026_organoid_ethical_review.md. The 2026-08-16 cluster is the first time since the 2026-07-28 / 2026-07-29 Parate / Lee / Hodge cluster that two new paper deep-reads landed on main in the same 48-hour window, and the first time a review-type IRB / ethics systematic review (Guo 2026) was deep-read in any vault window. 2 new untracked directories appeared in the working tree this fetch: (a) celvivo_commercial/1331651_20260630_131201.pdf (the 6-30 quote PDF migrated into a new folder); (b) templates/类器官IRB申请清单.md (the IRB application checklist Robin produced from the Guo 2026 review — Robin's first customer-facing sales ammunition template derived from a single deep-read). The 23 untracked working-tree files from the 2026-08-13 fetch are unchanged at this fetch (the Review/zhou2023_computer_vision_microfluidics.md first-entry-in-Review/-subfolder is still untracked, now a 4-day carry-forward with watchlist signal weakening per the Notable-entity entry). Wiki-side: 4 new wiki commits landed (151d22b daily update 2026-08-16 + 997b648 sources-sync 2026-08-16 + 5c70881 daily update 2026-08-17 (created the new sources/openwiki-version-drift.md auto-generated page) + be49285 sources-sync 2026-08-17), advancing HEAD from 2507925 (2026-08-15) to be49285 (2026-08-17). 9 dirty wiki files in the working tree (.last-update.json + quickstart.md + sources/README.md + sources/hackernews.md + sources/nocodb.md

  • sources/ragflow.md + sources/seafile.md + sources/web-search.md
  • sources/wikijs.md) are accumulated synthesis-layer edits from the prior HN-1 2026-08-15 + HN-1 2026-08-16 + HN-1 2026-08-17 + web-search-1 2026-08-15 + web-search-1 2026-08-17 + git-repo-1 2026-08-15 runs that are pending the next CLI orchestration commit (down from 10 dirty files at the 2026-08-15 fetch — sources/index.md got committed in the 151d22b 2026-08-16 daily update). One new wiki file added in the window: sources/openwiki-version-drift.md (auto-generated OpenWiki version drift monitor; reports v0.3.1 local → v0.3.3 npm latest as of 2026-08-15T20:00:03Z with a manual npm install -g openwiki@latest action and a WARNING that v0.3.1 → v0.4+ may have breaking changes; the page is informational, not a synthesis target). No /commitments.md row, no /open-questions.md row, no /personal-logistics.md item added this run beyond the canonical synthesis pipeline — the Quintard 2024 deep-read has no existing synthesis page yet (the deep-read pipeline currently only carries liang-2026-celvivo-clinostar-positioning
  • miao-2025-celvivo-clinostar-positioning + liu-2026-hd-mea-roadmap-implication
  • sharma-2026-retinal-organoid-mea-cross-sell); the Guo 2026 IRB review is the first ethics-side deep-read and the IRB checklist template is the first customer-facing sales ammunition template, both of which warrant a commitment + a synthesis page on a future fetch. Wiki edits this run: (a) /sources/git-repo.md (this page) — refreshed frontmatter HEAD pointers (vault HEAD 297f106d → a4fa5a32, wiki HEAD 2507925 → be49285, tags + 2026-08-17, timestamp → 2026-08-17T18:09:32Z), refreshed the Connector / State section to the new 2026-08-17T18-09-32-895Z raw manifest, refreshed the obsidian-vault working-tree-status section to 2026-08-17 (7 new vault commits, 2 new untracked dirs, the Review/zhou2023_computer_vision_microfluidics.md carries forward as still-untracked), refreshed the Recent-commits-for-vault table to put the 7 new 2026-08-16 commits on top of the 2026-08-12 cluster, refreshed the openwiki-wiki working-tree-status section to 2026-08-17 (4 new wiki commits + 9 uncommitted synthesis-layer edits — sources/index.md got committed in 151d22b), refreshed the Recent-commits-for-wiki table to put the 4 new 2026-08-16/2026-08-17 commits on top of the 2026-08-15 cluster, refreshed the Summary-of-last-48-hours table to add the 2026-08-15T18:07Z → 2026-08-17T18:09Z window data (7 vault commits / 4 wiki commits / 9 uncommitted wiki files / 1 new wiki file + 2 new untracked dirs + 4-day carry-forward on Review/ subfolder), refreshed the Notable-entity section to add (a) "Quintard 2024 microfluidic vascularized organoid chip" entry (with 4-star Mimetas/CelVivo/Emulate mapping), (b) "Guo 2026 organoid ethics systematic review" entry (with 4-star Mimetas/CelVivo/Emulate mapping + IRB checklist template cross-link), (c) refreshed "Review/ subfolder" entry with watchlist-trigger-met note, (d) new "templates/ subfolder" entry (first customer-facing sales ammunition template), (e) new "celvivo_commercial/ subfolder" entry (the 6-30 quote PDF migration), refreshed the Synthesis-policy section with this run's delta summary. No /themes.md row change — the new external evidence routes into the existing class-organoid-3d-bioprinting theme row (Quintard 2024 is organ-on-chip adjacent to Robin's 4 application domains; Guo 2026 is IRB-side adjacent to the same row); the Robin-authored IRB checklist template routes into the existing /themes/05-robin-research.md "Sales ammunition pipeline" section rather than a new theme row. No /open-questions.md row, no /personal-logistics.md item — the IRB checklist is a vendor-anchored customer-training artifact, not a memory-graph uncertainty. (b) /themes/05-robin-research.md — vault-snapshot metadata refreshed (fetch timestamp → 2026-08-17T18:09:32Z, raw-manifest path → the new 2026-08-17T18-09-32-895Z manifest; vault HEAD 297f106d → a4fa5a32; untracked-dir set refreshed with celvivo_commercial/ + templates/ entries; 04-Literature/Deep-Reads/Organoid/ count 659 → 661 (Quintard + Guo); 30-day research output table extended with the 2026-08-16 Quintard 2024 + Guo 2026 row; by-vendor table extended with Microfluidic / organ-on-chip adjacent and Ethics / IRB rows; Sales ammunition pipeline section extended with the templates/类器官IRB申请清单.md IRB checklist template). (c) /themes/01-organoid-equipment.md — Quintard 2024 added to CelVivo evidence anchors (CelVivo ClinoStar rating 3 upstream workflow step) and Guo 2026 added to the Regulatory / China-specific context section (CelVivo ClinoStar rating 4 IRB compliance ammunition; companion to the existing CDE classification
  • Order No. 818 items). (d) /sources/literature.md — Quintard 2024
  • Guo 2026 added to the 30-day deep-read index. (e) /sources/README.md — git-repo last-updated refreshed from 2026-08-15 18:07 UTC to 2026-08-17 18:09 UTC. (f) /quickstart.md — added the "Latest update — git-repo-1 (2026-08-17T18:09Z)" paragraph. Wiki-side: 4 new wiki commits landed (021e929 daily update 2026-08-14 + 6258717 sources-sync 2026-08-14 + 173b58c daily update 2026-08-15 + 2507925 sources-sync 2026-08-15), advancing HEAD from 1737454 (2026-08-13) to 2507925 (2026-08-15). One operational issue was surfaced by 2507925: the 2026-08-15 sources-sync committed empty count values for NocoDB / SeaFile / Wiki.js / RAGFlow (NocoDB 6614 → 0, Wiki.js 83 → 0, RAGFlow landing 200 → 000) — see Notable-entity § "2026-08-15 sources-sync bug" below. 10 dirty wiki files in the working tree (.last-update.json + quickstart.md + sources/README.md + sources/hackernews.md + sources/index.md + sources/nocodb.md + sources/ragflow.md + sources/seafile.md + sources/web-search.md
  • sources/wikijs.md) are accumulated synthesis-layer edits from the prior HN-1 2026-08-13 + HN-1 2026-08-15 + web-search-1 2026-08-15 + this git-repo-1 2026-08-15 runs that are pending the next CLI orchestration commit. Wiki edits this run: (a) /sources/git-repo.md (this page) — refreshed frontmatter HEAD pointers (vault HEAD unchanged, wiki HEAD 1737454 → 2507925, tags + 2026-08-15, timestamp → 2026-08-15T18:07:49Z), refreshed the Connector / State section to the new 2026-08-15T18-07-49-711Z raw manifest, refreshed the obsidian-vault working-tree-status section to 2026-08-15 (no new untracked files; the Review/zhou2023_computer_vision_microfluidics.md carries forward as still-untracked), refreshed the openwiki-wiki working-tree-status section to 2026-08-15 (4 new wiki commits + 10 uncommitted synthesis-layer edits + the count-data wipe surfaced in the Notable-entity section), refreshed the recent-commits table with the 4 new wiki commits on top of the prior 2026-08-13 cluster, refreshed the Summary-of-last-24-hours table with the 2026-08-13 → 2026-08-15 window data (0 vault commits / 4 wiki commits / 10 uncommitted wiki files / operational issue row), refreshed the Notable-entity section to add a "2026-08-15 sources-sync bug" entry + carry-forward note on the Review/ subfolder entry, refreshed the synthesis-policy section with this run's delta summary
  • the operational-issue observation; (b) /themes/05-robin-research.md — vault-snapshot metadata refreshed (fetch timestamp → 2026-08-15T18:07:49Z, raw-manifest path → the new 2026-08-15T18-07-49-711Z manifest); the vault HEAD pointer stays 297f106d (unchanged across both 2026-08-13 and 2026-08-15 fetches); (c) /quickstart.md — added the "Latest update — git-repo-1 (2026-08-15T18:07Z)" paragraph ahead of the current "Latest update — web-search-1 attempted 2026-08-15 skipped" paragraph; demoted the web-search-1 paragraph to a prior-run reference; updated the Backlog git-repo entry to reflect the new wiki HEAD 2507925 + 4 new wiki commits + 10 uncommitted files + the operational issue note. No /commitments.md row, no /open-questions.md row, no /personal-logistics.md item, no /themes.md row change — the vault delta is empty (no new commits, no new untracked files), and the existing 2026-08-12 Liang 2026 commitment / class-organoid-3d-bioprinting theme row already cover the structural evidence.

• Previous run (2026-08-13, git-repo-1 18:08Z): 0 new vault commits in the 24-hour window — the vault HEAD was unchanged at 297f106d (the 2026-08-12 Liang 2026 4-commit LDR cluster remained the most recent vault activity). The only vault-side delta was 1 new untracked file: 04-Literature/Deep-Reads/Review/zhou2023_computer_vision_microfluidics.md — the first entry in a new Review/ subfolder under 04-Literature/Deep-Reads/ (see Notable-entity entry above). 1 noise file (__pycache__/...pyc) was ignored. Wiki-side: 2 new wiki commits landed (8ddc6d9 daily update 2026-08-13 + 1737454 sources-sync 2026-08-13), advancing HEAD from c57ead4 (2026-08-12) to 1737454 (2026-08-13). 8 dirty wiki files in the working tree were synthesis-layer edits from the prior HN-1 2026-08-13 run that landed after 1737454 committed and were pending the next CLI orchestration commit.

• Previous run (2026-08-12, git-repo-1 18:08Z): 4 new vault commits on the same single Liang 2026 Sci Rep liver organoid paper walked through Robin's standard 3-stage LDR cycle (e542c977 adds file → 8699a154 page 946 9 项 SOP 重写版 → aacba7aa + 297f106d page 934 修齐 micro-revisions) — this was the net-new external evidence for that run. Wiki edits at that time are described in the synthesis-policy paragraph above; the canonical synthesis continues to live at /themes/01-organoid-equipment.md, /themes/05-robin-research.md, and /commitments.md liang-2026-celvivo-clinostar-positioning.

• The vault is a knowledge base, not a live signal stream; durable per-document synthesis (paper deep reads, sales scripts, customer files) requires reading individual files, which is delegated to the Hermes skill and RAGFlow.

• Future runs should keep this page structural. Promote a row to a canonical theme only when the connector observes a recurring workflow (e.g. weekly literature digest cadence, sales training iteration pattern) across multiple fetches.

• Process signal worth watching (2026-08-13): (a) New Review/ subfolder signal — Robin added a 20th subfolder under 04-Literature/Deep-Reads/ dedicated to review-type papers, with zhou2023_computer_vision_microfluidics.md as the first entry. If the subfolder accumulates ≥3 entries, this signals a formal review-paper stream is being built separately from the original-research stream; if it stays at 1 entry, it's a one-off. (b) Liang 2026's MOC linkage confirms the MOC pattern is in active use — the paper's related: field already names [[MOC-类器官与3D培养]] (the first MOC, created 2026-08-10) on the day of publication, not a future-state plan. Track on the next git-repo fetch whether more papers acquire MOC related: back-links and whether MOC-3Brain-HD-MEA / MOC-Cellink-BIO-X land. (c) Page 934 修齐 micro-revisions now appear on every new LDR cycle — 297f106d is the second paper (after 381fcbaa OVB-organoids 2026-08-11) where Robin applied the H1 去括号 / 元数据 bold / 📄PDF 文件名 alignment. The pattern appears to be the new standard end-state. (d) Phase A frontmatter batch rollout is still paused (only 6 of ~1,204 deep-reads received the 6-field frontmatter); no progress this run.

Next update

Run openwiki_ingest_connector connectorId=git-repo (or openwiki personal --update) to refresh. Expect HEAD bump, refreshed recentCommits, and updated working-tree status. rking-tree status.