openwiki-wiki/sources/git-repo.md

type, title, description, resource, tags, timestamp

type	title	description	resource	tags	timestamp
Reference	Git repo — evidence index (Obsidian vault, Robin)	Compact manifest of Robin's Obsidian vault + the local OpenWiki wiki, ingested through the local git-repo connector. Two configured repos: obsidian-vault at /home/ldw/workspace (main branch, HEAD a4fa5a32, 2026-08-16, 7 new vault commits in the 2026-08-15T18:07Z → 2026-08-17T18:09Z 48-hour window) and openwiki-wiki at /home/ldw/.openwiki/wiki (main branch, HEAD be49285, 2026-08-17). This page is a navigation index — content ingestion (paper deep reads, sales scripts, customer files) happens via the Hermes skill and RAGFlow, not here.	~/.openwiki/connectors/git-repo/config.json	git-repo evidence vault openwiki-wiki source 2026-08-17 2026-08-15 2026-08-13	2026-08-17T18:09:32Z

Git repo — evidence index (Obsidian vault + OpenWiki wiki)

Compact manifest of the two local git repos configured under the git-repo connector: Robin's Obsidian vault and the local OpenWiki wiki. This page is a navigation index — content ingestion (paper deep reads, sales scripts, customer files) happens via the Hermes skill and RAGFlow, not here. Keep this page terse and structural; it should help locate things in the vault, not summarize their content.

Connector

• Source instance: git-repo-1 (configured under ~/.openwiki/connectors/git-repo/config.json)
• Configured repos:
  • obsidian-vault → /home/ldw/workspace (Robin Obsidian vault, on main, HEAD a4fa5a323d6dcabeb9eccad49e636ee6ba5f87a6 as of 2026-08-16 +0800 — 7 new vault commits in the 2026-08-15T18:07Z → 2026-08-17T18:09Z 48-hour window: the 2026-08-16 Quintard 2024 Nat Commun 4-commit LDR cycle (0fc8db24 adds file 189 lines → 290e9635 -v2 修图床/双 H1/落款 → 24c713de -v3 Wiki.js 自带图床 6 张图 → 4073abf4 -v4 转发语标题/落款加粗/删 3Brain) + the 2026-08-16 Guo 2026 Front Cell Dev Biol 3-commit LDR cycle (2e6f5989 adds file 170 lines → 00f824f2 -v2 修图床 → a4fa5a32 -v3 补 Fig 1) — the first time two new paper LDR cycles land within the same 48-hour window since the 2026-07-28 / 2026-07-29 Parate / Lee / Hodge cluster. The 2026-08-12 Liang 2026 4-commit LDR cycle remains the prior baseline cluster).
  • openwiki-wiki → /home/ldw/.openwiki/wiki (the OpenWiki knowledge base itself, on main, HEAD be4928553364a654b888807a44438b738072c2ce as of 2026-08-17T +0800 — 4 new wiki-side commits in the 2026-08-15T18:07Z → 2026-08-17T18:09Z window: 151d22b daily update 2026-08-16 + 997b648 sources-sync 2026-08-16 + 5c70881 daily update 2026-08-17 + be49285 sources-sync 2026-08-17; the 5c70881 daily update also created the new sources/openwiki-version-drift.md auto-generated page).
• Auth: local paths only — no remote, no credentials.
• Latest fetch: 2026-08-17T18:09:32Z (raw manifest ~/.openwiki/connectors/git-repo/raw/2026-08-17T18-09-32-895Z/manifest.json).
• Source config: ~/.openwiki/connectors/git-repo/config.json
• State: ~/.openwiki/connectors/git-repo/state.json records latestIds per repo; the 2026-08-17 fetch observed vault HEAD bumped from 297f106d (2026-08-15 fetch) to a4fa5a32 (7 new vault commits in the 48-hour window) and bumped openwiki-wiki from 2507925 (2026-08-15 fetch) to be49285 (4 new wiki commits in the same 48-hour window, plus 1 new wiki-side file sources/openwiki-version-drift.md).

obsidian-vault — working-tree status (2026-08-17)

• Branch: main

• HEAD: a4fa5a323d6dcabeb9eccad49e636ee6ba5f87a6 (vault HEAD bumped from 297f106d across the 2026-08-17 fetch — 7 new commits in the 2026-08-15T18:07Z → 2026-08-17T18:09Z 48-hour window: the 2026-08-16 Quintard 2024 Nat Commun 4-commit LDR cycle

  • the 2026-08-16 Guo 2026 Front Cell Dev Biol 3-commit LDR cycle. Two new paper LDR cycles in the same 48-hour window is the first time this pattern has occurred since the 2026-07-28 / 2026-07-29 Parate / Lee / Hodge cluster).

• Ahead of origin/main: 20 commits new since 2026-08-03 fetch (was 13 at the 2026-08-15 fetch; the +7 delta is the Quintard 2024 + Guo 2026 clusters).

• Dirty: yes — the untracked file set +2 new entries in the 2026-08-17 48-hour window: celvivo_commercial/1331651_20260630_131201.pdf (the 6-30 quote PDF, moved into a new folder) + templates/类器官IRB申请清单.md (the IRB application checklist derived from Guo 2026; 180 lines; 7 mandatory points + 5 customer Q&A + China vs International flow + 10 attachments; Robin's first customer-facing template derived from a single deep-read). The carry-forward untracked set is unchanged: 8 × 02-Clients/Agents/区域-2026-0807.md distributor-rebuild files (per the 2026-08-07 Hermes hook 4 sweep) + the existing 14 working- folder files (Parfitt 2024 DJ1 LOF midbrain + Liu2026 / Miao2025 v2 / Miao2025 vascularized / Microbioreactor 2026 / __pycache__/literature_deepread_v6.cpython-312.pyc / dify精读进度-20260805.md / literature_deepread_v6.py / obsidian-vault/04-Literature/Deep-Reads/Review/zhou2023_computer_vision_microfluidics.md / obsidian-vault/rustdesk-selfhosted-2026-08-05.md / retinal_organoid_deep_read_2026-08-07.md / 文悦精读流水线.yml + v2/v3/v4/v5-clean variants). The Review/zhou2023_computer_vision_microfluidics.md first entry in the new Review/ subfolder is still untracked (Robin has not yet committed it) — the structural signal carried forward from the 2026-08-13 fetch and is now joined by 2 new untracked working-tree directories (celvivo_commercial/ + templates/).

• Working-tree status (raw manifest, abbreviated):

  Status	Path
  A (committed 2026-08-12, e542c977)	04-Literature/Deep-Reads/Liver/2026-08-12_Liang_2026_SciRep_liver_organoid_fibrosis_platform.md — NEW external evidence (Liang Y et al. Sci Rep 2026 DOI 10.1038/s41598-026-42990-2, PMID 41857098, 3 轨道 Hep-Orgs + Cho-Orgs + HSC, DAPT+Dex P1-P10 长程成熟, TGFβ 激活体外纤维化模型; Wiki.js Id=1716, NocoDB Id=770, SeaFile PDF + 7 真图)
  M (committed 2026-08-12, 8699a154)	same Liang 2026 file — page 946 9 项 SOP 重写版 (105+/122- lines)
  M (committed 2026-08-12, aacba7aa)	same Liang 2026 file — frontmatter title 改中文 + 与正文 H1 一致 (1-line touch)
  M (committed 2026-08-12, 297f106d)	same Liang 2026 file — 修齐 page 934 标杆 (H1 去括号/元数据用bold/📄PDF文件名, 5+/4- lines)
  A (committed 2026-08-16, a4fa5a32)	obsidian-vault/Literature/Deep-Reads/Organoid/guo_2026_organoid_ethical_review.md — NEW external evidence (Guo Z, Zhang N 2026 Front Cell Dev Biol DOI 10.3389/fcell.2026.1721946 — IRB / ethics systematic review; Wiki ID 1724, NocoDB Id 3298, 170 lines + 3 张真图; "与我们的产品" table lists CelVivo ClinoStar ⭐⭐⭐⭐ [临床转化类器官的伦理合规——7 大要点直接适用 IRB 申请] + Mimetas OrganoPlate ⭐⭐⭐⭐ [类器官 + 免疫细胞共培养伦理审查依据] + Emulate Organ-Chip ⭐⭐⭐; 3 commits 2e6f5989 → 00f824f2 → a4fa5a32 = adds → -v2 修图床 → -v3 补 Fig 1)
  A (committed 2026-08-16, 0fc8db24)	obsidian-vault/Literature/Deep-Reads/Organoid/quintard_2024_vasorganoid_chip.md — NEW external evidence (Quintard C et al. 2024 Nat Commun DOI 10.1038/s41467-024-45710-4 — microfluidic platform for vascularized organoid chips; Wiki IDs 1719/1720/1722, NocoDB Id 3297; 4 commits 0fc8db24 → 290e9635 → 24c713de → 4073abf4 = adds 189 lines → -v2 修图床/双 H1/落款 → -v3 Wiki.js 自带图床 6 张图 → -v4 转发语标题/落款加粗/删 3Brain; "与我们的产品" table lists Mimetas OrganoPlate ⭐⭐⭐⭐ [直接对标: Phaseguide 微流控技术用于血管化/肾/肠 organ-on-chip] + CelVivo ClinoStar ⭐⭐⭐ [类器官前段成熟期培养: BVO 在 hiPSC 分化到 day 15 需要悬浮旋转培养, ClinoStar 是该步骤的金标准; day 15 后才转入芯片, ClinoStar 是完整工作流的前置] + Emulate Organ-Chip ⭐⭐⭐)
  M (committed 2026-08-10)	04-Literature/Deep-Reads/Organoid/2026-07-29_Organoids_disease_modeling_treatment_2026_review.md (Phase A batch frontmatter — volume / pages / authors array; also touched by 6b717aef for related back-link)
  M (committed 2026-08-10)	CelVivo_精读报告_04_bioRxiv_PAH_Metabolomics.md (Phase A batch frontmatter — volume / pages / authors array; also touched by 6b717aef)
  M (committed 2026-08-10)	obsidian-vault/04-Literature/Deep-Reads/3Brain/shin-2024-thalamocortical-organoids-22q11ds.md (Phase A batch frontmatter; also touched by 6b717aef)
  M (committed 2026-08-10)	obsidian-vault/04-Literature/Deep-Reads/Cells/fernandez-vallone-2026-thsdc-brain-organoids.md (Phase A batch frontmatter; also touched by 6b717aef)
  M (committed 2026-08-10)	obsidian-vault/04-Literature/Deep-Reads/NBME-ShapeConformal/literature-liu-2026-nbme-shape-conformal-organoid.md (Phase A batch frontmatter; also touched by 6b717aef)
  M (committed 2026-08-10)	类器官综述_CMOS_HD_MEA_类器官电生理_2026-06-05.md (Phase A batch frontmatter; also touched by 6b717aef)
  M (committed 2026-08-10)	04-Literature/Deep-Reads/wang2024-org-on-chip.md (方案 2 样品 — 6 frontmatter fields + 7 alt descriptions; also touched by 6b717aef)
  A (committed 2026-08-10)	04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md (方案 1 — first MOC file; 95 lines; 沙牛《AI 时代的 Obsidian 公开课》课时 1 pattern; related: already lists [[MOC-3Brain-HD-MEA]] as a forward link)
  ?? (untracked)	02-Clients/Agents/全国经销商地图-2026-0807.md + 7 区域 *2026-0807.md files (8-07 distributor baseline refresh — see below)
  ?? (untracked, NEW 2026-08-17)	celvivo_commercial/1331651_20260630_131201.pdf — NEW untracked directory; the 6-30 quote PDF Robin migrated into a new celvivo_commercial/ folder; companion to the existing 05-Documents/Products/Celvivo/Industrial-Customers/ commercial-docs subtree
  ?? (untracked, NEW 2026-08-17)	templates/类器官IRB申请清单.md — NEW untracked directory; the IRB application checklist derived from the Guo 2026 ethics-review deep-read (180 lines; 7 mandatory points [样本来源/知情同意/数据隐私/共培养主体性/3R 动物福利/跨境监管/长期保存与终止使用] + 5 customer Q&A + China vs International flow table + 10 attachments + 7 citations); Robin's first customer-facing template derived from a single deep-read — materializes the "Robin 业务定位: 类器官厂家给三甲医院 IRB 申请的标准模板 + Robin 客户培训材料核心" framing from the Guo 2026 deep-read
  ?? (untracked)	04-Literature/Deep-Reads/Brain/2026-08-06_Parfitt_GM_et_al_NatCommun_2024_DJ1_LOF_midbrain_organoid_PD.md
  ?? (untracked)	Liu2026_NBME_shape_conformal_organoid.md
  ?? (untracked)	Miao2025_Cell_v2.md
  ?? (untracked)	Miao2025_Cell_vascularized_organoid.md
  ?? (untracked)	Microbioreactor_2026_Rosero_FrontBioeng.md
  ?? (untracked)	__pycache__/literature_deepread_v6.cpython-312.pyc — NEW (2026-08-13) Python compiled cache file (build noise from running literature_deepread_v6.py, ignored)
  ?? (untracked)	dify精读进度-20260805.md
  ?? (untracked)	literature_deepread_v6.py
  ?? (untracked)	obsidian-vault/04-Literature/Deep-Reads/Review/zhou2023_computer_vision_microfluidics.md — NEW (2026-08-13) first entry in the new Review/ subfolder (Zhou 2023 computer vision + microfluidics — Robin deep-read in progress, untracked, future-commit candidate)
  ?? (untracked)	obsidian-vault/rustdesk-selfhosted-2026-08-05.md
  ?? (untracked)	retinal_organoid_deep_read_2026-08-07.md
  ?? (untracked)	文悦精读流水线.yml + v2/v3/v4/v5-clean variants

  The 8 untracked *2026-0807.md files in 02-Clients/Agents/ are the 2026-08-07 distributor baseline refresh — see the "Distributor map refresh (2026-08-07)" section below for synthesis. The 2 NEW untracked files this fetch are: (a) Review/zhou2023_computer_vision_microfluidics.md — first entry in a new deep-read subfolder (see Notable-entity entry below); (b) __pycache__/...pyc — build noise, ignored.

Recent commits (latest first)

Date	Hash	Note
2026-08-16	a4fa5a32	literature: review 类 Guo 2026 -v3 补 Fig 1 — in-place update ID 1724, 3 张图全
2026-08-16	00f824f2	literature: review 类 Guo 2026 -v2 修图床 — in-place update ID 1724, 加 2 张 Wiki.js 自带图
2026-08-16	2e6f5989	literature: 精读 Guo 2026 Front Cell Dev Biol - 类器官伦理审查 (review 类, Wiki ID 1724, NocoDB Id 3298) — NEW external evidence (类器官研究 IRB / 伦理审查 7 大强制要点系统综述, 嘉兴市第一医院 + 嘉兴大学医学院视角)
2026-08-16	4073abf4	literature: 精读 Quintard 2024 -v4 — 转发语标题/落款加粗/删3Brain
2026-08-16	24c713de	literature: 精读 Quintard 2024 -v3 Wiki.js 自带图床 (ID 1722, 6 张图永久)
2026-08-16	290e9635	literature: 精读 Quintard 2024 -v2 修图床/双 H1/落款 (Wiki ID 1720)
2026-08-16	0fc8db24	literature: 精读 Quintard 2024 Nat Commun - 微流控血管化类器官芯片 (Wiki ID 1719, NocoDB Id 3297) — NEW external evidence (10 通道并行微流控 + hiPSC-BVO 30 天功能性灌注培养 + 跨类器官验证)
2026-08-12	297f106d	literature: 修齐 page 934 标杆 — H1 去括号 / 元数据用 bold / 📄PDF 文件名 (Liang 2026 v3)
2026-08-12	aacba7aa	literature: frontmatter title 改中文 + 与正文 H1 一致 (Liang 2026 v2)
2026-08-12	8699a154	literature: Liang 2026 Sci Rep liver organoid fibrosis - page 946 9 项 SOP 重写版 (Liang 2026 v2; 105+/122- lines; core-question / research-model / 6-finding 3-stage tables / 6 SeaFile Fig / "与我们的产品" 4-star / 4-paper refs / 转发语 / 完整落款)
2026-08-12	e542c977	literature: Liang 2026 Sci Rep liver organoid + fibrosis platform (Id=770 NocoDB) — NEW external evidence (3 轨道 Hep/Cho/HSC + DAPT+Dex P1-P10 长程成熟 + TGFβ 激活 HSC 体外纤维化模型; 7/7 Ollama qwen2.5vl 视觉审核通过; SeaFile 7/7 公网 200 验真; 飞轮 PATCH comm Id=87 + product Id=10 + NocoDB PATCH 770)
2026-08-10	d97b39ed	Phase A 批量：6 篇精读加 Front Matter 6 字段 (doi/journal/year/volume/pages/authors/pmid) — Organoids 2026 review + CelVivo PAH + Shin 2024 + Fernandez Vallone 2026 + Liu 2026 + 类器官综述_CMOS_HD_MEA
2026-08-10	3b929c2f	wang2024 方案 2 样品：6 个 Front Matter 字段 + 7 张图加 alt 描述 — wang2024-org-on-chip.md
2026-08-10	6b717aef	MOC 方案 1 样品：建 1 个 MOC + 7 篇加 Front Matter (related: 反链) — first MOC MOC-类器官与3D培养.md created; 7 papers got related: back-link frontmatter
2026-08-09	a14758b1	精读: Wang 2024 Theranostics 类器官-芯片综述 (7 张配图 + Wiki.js ID 1700) — first Organoid-on-Chip 综述 / 7 大主题板块
2026-08-08	d7df3830	cells paper v2: 双 H1 + 5张真图 (xref) — Fernandez Vallone 2026
2026-08-08	6c16dc05	精读: Fernandez Vallone 2026 Cells hiPSC 脑类器官 THSDC
2026-08-07	65fef021	fix: v2 with SeaFile links — Microbioreactor 2026
2026-08-07	18bee69f	feat: Microbioreactor design 2026 Front Bioeng Biotechnol Mini Review (PMID 42516424)
2026-08-08	1614ccf9	fix: v11 - forwarding per skill template (Liu 2026)
2026-08-08	a7cfb8a4	fix: final - per Research SOP strict + clean internal traces (Liu 2026)
2026-08-08	d1e8c6dd	fix: v5 - per Research SOP + page 946 benchmark (Liu 2026)
2026-08-08	b7882b81	fix: v4 - add forward message (Liu 2026)
2026-08-08	84e93402	fix: v3 - Fig 3 restored from page 6, audit table removed (Liu 2026)
2026-08-08	a69ad9c4	literature: liu 2026 NBME shape-conformal organoid
2026-08-08	1c05eee7	literature: miao 2025 cell organoid vascularization v2
2026-08-08	a0810433	精读: Sharma K 2026 Cell Stem Cell 视网膜类器官血管化RGC存活与功能成熟
2026-07-29	2341383e	fix(hook4): 湖北行去掉 'Robin 8 月出差高发地' 残留 (Robin 真实出差意图)
2026-07-29	aa8fd2bc	fix(hook4): 改标题 '下次出差' → '按 xlsx 缺口', Robin 后续自规划出差路径
2026-07-29	4b237a82	feat(hook): 4 个经销商管理 Hook 升级
2026-07-29	b9da34dc	fix(literature): Organoids 2026 综述 - 按 literature-deep-read-review SOP 重写
2026-07-29	0cd44fa0	feat(literature): 精读 Organoids for disease modeling and treatment 2026 综述
2026-07-28	642e3dc6	feat(agent): 新增代理商技术同事董慧群档案 (推 CelVivo 产品)
2026-07-28	2718e46d	feat(literature): Parate 2020 SCRT — PEMF 增强 MSC 旁分泌功能促软骨再生
2026-07-28	032de92f	feat: 精读 Lee 2025 Front Vet Sci 犬脂肪源 MSC 3D 球体

The 2026-08-16 cluster is a two-paper LDR cycle on the same day covering both an organ-on-chip microfluidic platform paper and an organoid ethical-review systematic-review paper:

• Quintard C et al. (2024) Nat Commun DOI 10.1038/s41467-024-45710-4 — a microfluidic platform for vascularized organoids-on-chip. The paper establishes: (i) 10-channel parallel microfluidic chip (COC 热压成型, U 型捕获位 300-800 µm 可调); (ii) fibrin + Matrigel hydrogel with Landau-Levich-Bretherton 效应 → 100% 捕获效率 in 10 sec per channel; (iii) hiPSC-derived blood vessel organoids (BVO, day 15)
  • GFP-HUVEC + 纤维细胞共培养 → 30 天功能性灌注培养; (iv) 壁剪切速率 27-2000 s⁻¹, mean 134-531 s⁻¹ (与人体毛细血管生理范围 50-1900 s⁻¹ 完美匹配); (v) 层级化血管: 37 µm 上游动脉-静脉 + 8 µm BVO 毛细管. The 4 commits are the same single file obsidian-vault/Literature/Deep-Reads/Organoid/quintard_2024_vasorganoid_chip.md walked through Robin's standard LDR cycle: (a) 0fc8db24 adds the file (189 lines, single-pass entry); (b) 290e9635 rewrites to -v2 修图床/双 H1/落款; (c) 24c713de adds -v3 Wiki.js 自带 图床 6 张图 (永久); (d) 4073abf4 is the -v4 转发语标题/落款 加粗 + 删 3Brain 工具名硬门槛合规修正. The "与我们的产品" table on the paper lists Mimetas OrganoPlate ⭐⭐⭐⭐ (直接对标: Phaseguide 微流控技术) + CelVivo ClinoStar ⭐⭐⭐ (类器官前段成熟期培养: BVO 在 hiPSC 分化到 day 15 需要悬浮旋转培养, ClinoStar 是该步骤 的金标准; day 15 后才转入芯片, ClinoStar 是完整工作流的前置) + Emulate Organ-Chip ⭐⭐⭐.
• Guo Z, Zhang N (2026) Front Cell Dev Biol DOI 10.3389/fcell.2026.1721946 — an IRB / ethical-review systematic-review paper for organoid biomedical research. The paper establishes: (i) 7 大强制要点 (样本来源合法性 / 捐赠者知情同意 [unlimited expansion / long-term cryopreservation / inter-lab sharing / cross-border / future unspecified research / commercial use / withdrawal mechanism] / 数据隐私与去标识化 / 共培养产物主体性评估 [Guo 2026 首次提出] / 动物福利 3R 原则 / 跨境监管合规 [中国 / 美国 / 欧盟 / 日本 / 韩国 对照表] / 长期保存与终止使用); (ii) 中国 IRB 实务视角 + 国际 ISSCR / GDPR / OHRP 双重参照 (作者团队 = 嘉兴市第一医院医学伦理 委员会 + 嘉兴大学医学院, 中国 IRB 实践者); (iii) 共培养产物 "新伦理实体" 框架 = 类器官 + 免疫细胞共培养 (CAR-T 培养) 不构成 "新生物体" 但构成 "新伦理实体", 需要独立审查. The 3 commits are the same single file obsidian-vault/Literature/Deep-Reads/Organoid/guo_2026_organoid_ethical_review.md walked through Robin's standard LDR cycle: (a) 2e6f5989 adds the file (170 lines, single-pass entry); (b) 00f824f2 -v2 修 图床 (加 2 张 Wiki.js 自带图); (c) a4fa5a32 -v3 补 Fig 1 (3 张图全) — Fig 1 is the "类器官共培养模型" 概念图 (Robin 8-16 实战反思: 综述类概念图通常较小, 提取阈值要从 0KB 起步全收, 再按 caption 关联; 之前 >200KB 过滤漏了 Fig 1). The "与我们的产品" table on the paper lists CelVivo ClinoStar ⭐⭐⭐⭐ (临床转化类 器官的伦理合规——本文 7 大要点直接适用于 ClinoStar 客户 IRB 申请; Robin 推广 ClinoStar 给三甲医院时, 可附带本框架作为增值) + Mimetas OrganoPlate ⭐⭐⭐⭐ (类器官共培养芯片的伦理审查依据—— Mimetas 主打"类器官 + 免疫细胞共培养", 本文主题 B 的共培养伦理 框架直接适用) + Emulate Organ-Chip ⭐⭐⭐ (类器官 + 微流控 芯片的跨境监管参考).

The 2026-08-12 cluster is a single-paper LDR cycle on Liang Y et al. (2026) Sci Rep DOI 10.1038/s41598-026-42990-2 — a mouse liver organoid platform paper from 澳门科技大学 + 香港大学 that establishes: (i) single-tissue 3-轨道 (Hep-Orgs + Cho-Orgs + HSC) separation; (ii) DAPT (Notch 抑制) + Dexamethasone for P1-P10 长程 稳定成熟 (ALB / PAS / LDL / CYP all stable across 10 passages — single DAPT only sustains P5); (iii) TGFβ 5-7 day activation of qHSC → aHSC (Acta2 / Col1a1 上调); (iv) aHSC 共培养诱导 Hep-Orgs EMT (Snail / Twist / Vimentin ↑; ALB / CK8 ↓; Lgr5 / EpCAM ↓; Ki67 ↓) = 体外肝纤维化模型. The 4 commits are the same single file 04-Literature/Deep-Reads/Liver/2026-08-12_Liang_2026_SciRep_liver_organoid_fibrosis_platform.md walked through Robin's standard 3-stage SOP cycle: (a) e542c977 adds the file (186 lines, single-pass entry); (b) 8699a154 rewrites the same file to the page 946 9 项 SOP 标杆 (105+/122- lines, adding the 6 核心发现 三段式 tables + 6 SeaFile Fig + "与我们的产品" 4-star table + 4-paper 参考文献 + 转发语 + 完整落款 + SeaFile PDF link); (c) aacba7aa + 297f106d are the page 934 修齐 micro-revisions (frontmatter title 改中文 / H1 去括号 / 元数据用 bold 单行 / 📄PDF 文件名 with actual filename) — the same alignment Robin applied across the 2026-08-11 OVB-类器官 cycle. The "与我们的产品" 4-star table on the paper lists CelVivo ClinoStar ⭐⭐⭐⭐ (P1-P10 长程扩增对应 旋转培养 30+ 天无剪切; HSC 静止态在模拟微重力下 7+ 天维持) + CelVivo ClinoReactor ⭐⭐⭐⭐ (单组织 3 轨道分通道灌流; TGFβ 时间程序 精确切换) + CelVivo PhaseHolographic 成像 ⭐⭐⭐ + 3Brain HD-MEA ⭐⭐⭐ (肝-神经互作延伸).

No new vault commits landed in the 2026-08-12T18:08Z → 2026-08-13T18:08Z window — the vault HEAD is unchanged at 297f106d. The 2026-08-12 Liang 2026 cluster remains the most recent committed vault activity. One new uncommitted file appeared in the working tree this fetch: 04-Literature/Deep-Reads/Review/zhou2023_computer_vision_microfluidics.md — the first entry in a new Review/ subfolder (see the Notable-entity section below).

7 new vault commits landed in the 2026-08-15T18:07Z → 2026-08-17T18:09Z window — the vault HEAD bumped from 297f106d to a4fa5a32. The two 2026-08-16 LDR cycles (Quintard 2024 microfluidic organ-on-chip + Guo 2026 organoid ethics systematic review) are the first time since the 2026-07-28 / 2026-07-29 Parate / Lee / Hodge cluster that two new paper deep-reads landed on main in the same 48-hour window. The 2026-08-16 cluster replaces the 2026-08-12 Liang 2026 cluster as the most recent committed vault activity. Two new untracked directories appeared in the working tree this fetch: celvivo_commercial/1331651_20260630_131201.pdf (the 6-30 quote PDF migrated into a new folder) + templates/类器官IRB申请清单.md (the IRB application checklist derived from Guo 2026 — Robin's first customer-facing sales ammunition template produced from a single deep-read; see the Notable-entity section below for synthesis).

The 2026-08-10 cluster is a frontmatter-hygiene + MOC-discipline sprint rather than new external evidence: (a) Phase A batch (d97b39ed) standardized 6 deep-read notes with the structured 6-field frontmatter (doi / journal / year / volume / pages / authors array / pmid) that the prior notes had been missing; (b) 方案 2 样品 (3b929c2f) added 7 image alt descriptions on top of the 6-field frontmatter for wang2024-org-on-chip.md; (c) MOC 方案 1 样品 (6b717aef) created Robin's first Map-of-Content file (04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md, 95 lines, 沙牛《AI 时代的 Obsidian 公开课》课时 1 pattern) and added related: back-link frontmatter to 7 papers. The MOC's own related: list already names the next planned MOC — [[MOC-3Brain-HD-MEA]] — plus [[02-Clients/Agents/_known_associations]] and [[02-Active-Deals/CellShot-TriArm-Demo-计划-v2-老师版-2026-07-20]], so the MOC pattern is expected to extend.

The 2026-08-08 cluster (prior manifest) was the literature flywheel-sync output (Liu 2026, Miao 2025 v2, Sharma 2026) — already indexed on /sources/literature.md. The 2026-08-07 / 2026-08-08 micro-revisions on Liu 2026 (a69ad9c4 → 1614ccf9) are the 8-step SOP rewrite cycle (v3 → v11) Robin re-ran on the same paper.

openwiki-wiki — working-tree status (2026-08-17)

• Branch: main
• HEAD: be4928553364a654b888807a44438b738072c2ce (the chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-17) commit — same auto-source-sync job that carried the 2026-08-15 count-data wipe; see Notable-entity § "2026-08-15 sources-sync bug" for the operational note).
• Working-tree state: 9 modified files (uncommitted — pending next CLI orchestration), down from 10 at the 2026-08-15 fetch (the sources/index.md from the 2026-08-15 dirty set was committed in the 2026-08-16 daily update 151d22b). The 9 dirty files are:
  • .last-update.json — CLI metadata, will be updated when this run's status: complete lands.
  • quickstart.md — contains the accumulated "Latest update" paragraphs from the prior HN-1 2026-08-15 + web-search-1 2026-08-15
    • git-repo-1 2026-08-13 runs, plus the new "Latest update — git-repo-1 (2026-08-15T18:07Z)" paragraph this run is adding.
  • sources/README.md — refreshed connector-roll table row for web-search-1 (added the 2026-08-15 skip to the 4-entry skip streak)
    • added frontmatter placeholders to nocodb.md / ragflow.md / seafile.md / wikijs.md during the 2026-08-15 daily update.
  • sources/hackernews.md — accumulated "Latest update — 2026-08-15 18:00 UTC" + "Latest update — 2026-08-16 18:00 UTC" + "Latest update — 2026-08-17 18:00 UTC" sections from the prior HN-1 2026-08-15 + HN-1 2026-08-16 + HN-1 2026-08-17 runs (Auto-research with codex 232x Faster Kernel + Anthropic multi-agent
    • Stripe/OpenRouter + Copilot Autofix + Qwen 3.8 27B + Agent Mesh flag-for-traceability callouts + the 4th / 5th / 6th consecutive empty / noise-only Algolia lane streak notes) — landed in uncommitted state during the HN-1 runs.
  • sources/nocodb.md — openwiki_generated: true placeholder frontmatter auto-applied during the 2026-08-15 daily update + carried forward in 2026-08-16 + 2026-08-17 daily updates; count data wiped by 2507925 2026-08-15 sources-sync (NocoDB went from 6614 → 0 records).
  • sources/ragflow.md — same openwiki_generated: true placeholder auto-applied during the 2026-08-15 daily update; count data wiped by 2507925 2026-08-15 sources-sync (landing went from 200 → 000).
  • sources/seafile.md — same openwiki_generated: true placeholder auto-applied during the 2026-08-15 daily update; count data wiped by 2507925 2026-08-15 sources-sync (libraries table emptied — SeaFile was already empty in 1737454 already — a separate, older cron issue not introduced by 2507925).
  • sources/web-search.md — accumulated "2026-08-15 attempted update — skipped" + "2026-08-17 attempted update — skipped" sections from the web-search-1 2026-08-15 + 2026-08-17 runs (5th + 6th consecutive skips on the same code path).
  • sources/wikijs.md — same openwiki_generated: true placeholder auto-applied during the 2026-08-15 daily update; count data wiped by 2507925 2026-08-15 sources-sync (Wiki.js went from 83 → 0 unique pages; ID range 22..1704 → 0..0).
• Auth: local path only — no remote, no credentials.
• New file in this window: sources/openwiki-version-drift.md was created in the 2026-08-17 daily update commit 5c70881 (auto- generated page that tracks OpenWiki installed-vs-npm-latest version drift; reports v0.3.1 local → v0.3.3 npm latest as of 2026-08-15T20:00:03Z; the page sits on the wiki to surface the drift without an external daemon).
• Auth: local path only — no remote, no credentials.

Recent commits (latest first)

Date	Hash	Note
2026-08-17	be49285	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-17)
2026-08-17	5c70881	chore: daily update 2026-08-17 (added sources/openwiki-version-drift.md auto-generated page + refreshed HN-1 / web-search-1 / git-repo-1 sections)
2026-08-16	997b648	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-16)
2026-08-16	151d22b	chore: daily update 2026-08-16 (committed sources/index.md from the 2026-08-15 dirty set; refreshed HN-1 / web-search-1 / git-repo-1 / themes/05-robin-research sections)
2026-08-15	2507925	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-15) — count-data wipe (NocoDB 6614 → 0, Wiki.js 83 → 0, RAGFlow landing 200 → 000); see Notable-entity § "2026-08-15 sources-sync bug"
2026-08-15	173b58c	chore: daily update 2026-08-15 (added OKF frontmatter to nocodb.md / ragflow.md / seafile.md / wikijs.md)
2026-08-14	6258717	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-14)
2026-08-14	021e929	chore: daily update 2026-08-14
2026-08-13	1737454	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-13)
2026-08-13	8ddc6d9	chore: daily update 2026-08-13 (commitment + quickstart + sources/literature + sources/web-search + themes/01-organoid-equipment + themes/05-robin-research from the HN-1 2026-08-13 synthesis pass)
2026-08-12	c57ead4	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-12)
2026-08-12	431ee6a	chore: daily update 2026-08-12
2026-08-11	b64ae41	lit: PMID 41536916 Bioactive Materials AIVOs 综述 (Wiki.js 1711)
2026-08-11	523ee7f	lit: PMID 41686639 Cell Reports TNBC DEO + ROCK (Wiki.js 1710)
2026-08-11	9be4f55	lit: PMID 41909700 Front Immunol 2026 类器官-小胶质细胞综述 (Wiki.js 1709)
2026-08-11	cc69ece	lit: PMID 42041571 v4 - 按 literature-deep-read-research 9 项强制格式
2026-08-11	b4bc8d9	lit: PMID 42041571 修正 - 真实PDF + 10张真图链接
2026-08-11	12480ab	lit: 修正 wiki_url 到真实内网地址
2026-08-11	cdc59c5	lit: PMID 42041571 OVB-organoids vs cerebral organoids Cells 2026
2026-08-11	2bcde39	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-11)
2026-08-11	7556e31	chore: daily update 2026-08-11
2026-08-09	dde053a	auto: 2026-08-09 Wang 2024 Theranostics OrgOC 综述精读入口
2026-08-09	3267338	chore: daily update 2026-08-09
2026-08-09	06f60e1	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-09)
2026-08-08	c94940c7	feat: add Microbioreactor 2026 v4 (PMID 42516424, ID 1696)
2026-08-08	7f65024	feat: add Microbioreactor 2026 v3 (PMID 42516424)
2026-08-08	ea4f14a	feat: add Microbioreactor 2026 v2 (PMID 42516424)
2026-08-08	a193e46	feat: add Microbioreactor 2026 (PMID 42516424) deep-read entry
2026-08-08	bf90a91	fix: liu 2026 wiki link to main path
2026-08-08	cf1dbe0	fix: liu 2026 final link
2026-08-08	26efd2f	fix: liu 2026 v5 link
2026-08-08	e18993a	fix: liu 2026 v4 link
2026-08-08	b206bd9	fix: liu 2026 v3 link
2026-08-08	c26dbdf	fix: liu 2026 wiki link to v2
2026-08-08	703c3d4	literature: liu 2026 NBME shape-conformal organoid
2026-08-08	1b78735	literature: miao 2025 cell v2
2026-08-08	5adc406	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-08)
2026-08-08	037c5f3	lit: add Sharma K 2026 Cell Stem Cell vRO retinal organoid (PMID 41529691)
2026-08-07	9e80977	feat(openwiki): complete data flywheel activation (2026-08-07)
2026-08-07	45af5a4	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-07)
2026-08-07	bcd4a4f	chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-07)
2026-08-07	0bbef0f	feat(openwiki v0.3.1 --update): generate themes 4-5 + index.md + themes/ + sources/ index (2026-08-07)
2026-08-07	285c53b	feat(openwiki v0.3.1): add YAML frontmatter + install-id markers from initial init run (2026-08-07)
2026-07-24	3102e96	feat(sources): 全国 261 家经销商地图 (2026-07-24, 不含敏感信息)

The wiki repo is the OpenWiki output itself — it persists across update runs. 4 new wiki-side commits landed in the 2026-08-13T18:08Z → 2026-08-15T18:07Z window: (a) 021e929 (2026-08-14 +0800 02:18, chore: daily update 2026-08-14); (b) 6258717 (2026-08-14 +0800 02:30, chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-14)); (c) 173b58c (2026-08-15 +0800 02:00, chore: daily update 2026-08-15 — added OKF frontmatter to nocodb.md / ragflow.md / seafile.md / wikijs.md); (d) 2507925 (2026-08-15 +0800 02:31, chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-15) — count-data wipe carried into the source pages; see Notable-entity § "2026-08-15 sources-sync bug" below). Between these 4 commits, the wiki HEAD advanced from 1737454 (2026-08-13 sources-sync) to 2507925 (2026-08-15 sources-sync). The 6 wiki commits from 2026-08-11 / 2026-08-12 (7556e31 / 431ee6a daily + 2bcde39 / c57ead4 sources-sync + the 6 lit-PMID commits on 2026-08-11 + 2bc03f3 / 06f60e1 / 5adc406 / 3267338 / dde053a from the 2026-08-08 / 2026-08-09 cluster) are all already in 2507925's ancestry. The Liang 2026 wiki sync has not yet landed (the /sources/literature.md short row is in working tree only); the next wiki commit should add a fuller Liang 2026 row when the synthesis pipeline catches up.

Summary of last 48 hours

Window (UTC)	Vault	Wiki
2026-08-15T18:07:49Z → 2026-08-17T18:09:32Z	HEAD 297f106d → a4fa5a32 (7 new commits: 0fc8db24 + 290e9635 + 24c713de + 4073abf4 Quintard 2024 Nat Commun microfluidic vascularized organoid chip 4-commit LDR cycle + 2e6f5989 + 00f824f2 + a4fa5a32 Guo 2026 Front Cell Dev Biol organoid ethics systematic review 3-commit LDR cycle — first time since the 2026-07-28 / 2026-07-29 Parate / Lee / Hodge cluster that two new paper deep-reads landed on main in the same 48-hour window)	HEAD 2507925 → be49285 (4 new commits: 151d22b daily update 2026-08-16 + 997b648 sources-sync 2026-08-16 + 5c70881 daily update 2026-08-17 + be49285 sources-sync 2026-08-17)
Net new external evidence	2 new paper deep-reads: Quintard 2024 Nat Commun microfluidic vascularized organoid chip + Guo 2026 Front Cell Dev Biol organoid ethics systematic review. 2 new untracked directories: celvivo_commercial/1331651_20260630_131201.pdf (the 6-30 quote PDF migrated into a new folder) + templates/类器官IRB申请清单.md (the IRB application checklist derived from Guo 2026 — Robin's first customer-facing sales ammunition template produced from a single deep-read). The Review/zhou2023_computer_vision_microfluidics.md first-entry-in-Review/-subfolder is still untracked, carrying forward from the 2026-08-13 fetch	1 new wiki file: sources/openwiki-version-drift.md (auto-generated OpenWiki version-drift monitor; v0.3.1 local → v0.3.3 npm latest as of 2026-08-15T20:00:03Z). Synthesis-layer edits accumulated across the prior HN-1 2026-08-13 + HN-1 2026-08-15 + HN-1 2026-08-16 + HN-1 2026-08-17 + web-search-1 2026-08-15 + web-search-1 2026-08-17 + git-repo-1 2026-08-13 + git-repo-1 2026-08-15 runs are pending the next CLI commit cycle
Untracked → committed migrations	Quintard 2024 file (4 commits) + Guo 2026 file (3 commits) all moved from absent → committed on main; the 2 new untracked directories are net-new in this window	none of the 9 dirty files were committed in this window (the sources/index.md from the 2026-08-15 dirty set was committed by the 2026-08-16 daily update 151d22b; the remaining 9 dirty files are uncommitted synthesis edits accumulated across the prior HN-1 + web-search-1 + git-repo-1 runs); the 9 dirty files (.last-update.json + quickstart.md + sources/{README,hackernews,nocodb,ragflow,seafile,web-search,wikijs}.md) are awaiting the next CLI commit cycle
Operational issue carried over from prior runs	n/a	2507925 2026-08-15 sources-sync bug + the 2026-08-16 997b648 + 2026-08-17 be49285 sources-syncs (which re-applied the same operational pattern as 2507925 — NocoDB / Wiki.js / RAGFlow count values stayed zero across all 3 sources-syncs). The on-disk ~/.openwiki/connectors/web-search/config.json is unaffected — this is a wiki-side CRON issue with the auto-source-sync job, not a connector config issue. Recorded for traceability on /sources/git-repo.md Notable-entity § "2026-08-15 sources-sync bug" and on each affected /sources/{nocodb,ragflow,seafile,wikijs}.md page. The data is recoverable from git show 8ddc6d9:sources/nocodb.md etc. for any future recovery commit

Vault navigation index

The vault uses a numbered top-level layout. Scripts, caches, and temp* working folders are excluded from this index.

Dir	Purpose	Size hint
01-Active-Sales/	Active sales pipeline files (board + per-account)	6 .md
02-Active-Deals/	Deal-level active docs	1 .md
02-Clients/, 02-Contacts/	Client & contact records	sparse
03-Product/	Product briefs (e.g. 3Brain-Maxwell comparison)	1 .md
03-Resources/Agents/	Distributor / agent profiles	a handful
03-Resources/End-Customers/	End-customer dossiers (3Brain MEA accounts, etc.)	11+ .md
03-Resources/ITX-24h-Host/	Personal 24h Hermes-Agent / AI-workflow host build config (2026-07-31 untracked; not yet on main)	1 .md
04-Literature/	Paper deep-reads + curated vendor PDFs	see breakdown
05-Documents/Contracts/	Signed/pending contracts (Celvivo subfolder)	—
05-Documents/Products/	Vendor-facing product docs (Celvivo/Industrial-Customers)	—
05-Documents/{Proposals,Quotes,Visit-Plans}/	Active commercial docs	—
05-Products/	In-house product briefs (MappingLab family)	2 .md
06-Sales/Competitors/	Competitor tracking	—
06-Sales/Configurations/	Product configurations	—
06-Sales/Content/{FAQ,Pain-Points,PPT-Scripts,Success-Stories,Training-Materials,推文模板}/	Sales content library	—
06-Sales/{Price-List,Product-Mapping,Recommendation-Engine}/	Sales tooling	—
99-Templates/	Reusable Obsidian templates	14 .md
memory/	Daily reports, weekly digests, .dreams, archive	147 .md

04-Literature/Deep-Reads/ breakdown

Markdown file counts per deep-read subfolder:

Subfolder	.md count
Organoid/	661 (+2 from 2026-08-16 — Quintard 2024 Nat Commun microfluidic vascularized organoid chip + Guo 2026 Front Cell Dev Biol organoid ethics systematic review)
Celvivo/	142
3Brain/	136
Cellink/	129
Organoid-List/	51
Product-Reports/	38
Brain/	11
Brain-Tumor/	9
Cancer/	6
Liver/	6
Other/	6
RegenMed/	1
3Brain MEA/	3
Cardiac/	2
Kidney/	2
Retinal/	1
Microbioreactor/	1 (new as of 2026-08-07 — Rosero 2026 Front Bioeng Biotechnol)
Cells/	1 (new as of 2026-08-08 — Fernandez Vallone 2026 Cells THSDC)
Review/	1 (new as of 2026-08-13 — Zhou 2023 computer vision + microfluidics, untracked)
templates/	1 (new as of 2026-08-17 — 类器官IRB申请清单.md, derived from the Guo 2026 ethics deep-read; Robin's first customer-facing template produced from a single deep-read, untracked)
celvivo_commercial/	1 (new as of 2026-08-17 — 1331651_20260630_131201.pdf, the 6-30 quote PDF migrated into a new folder, untracked)

Total ≈ 1,207 deep-read notes on main (+2 from the 2026-08-16 Quintard 2024 + Guo 2026 clusters). Review/ zhou2023 computer vision + microfluidics, untracked — only counts once committed; +2 working-tree files in the new templates/ + celvivo_commercial/ directories, both untracked). The 2026-08-16 Quintard 2024 + Guo 2026 cluster is the most recent committed deep-read additions; the 2026-08-07 / 2026-08-08 cluster (Microbioreactor + Cells) remains the prior committed cluster. CelVivo, 3Brain, Cellink, and the broad Organoid/ bucket cover Robin's product KB per the wiki goal focus areas (类器官培养与设备, 3D 生物打印). The new templates/ folder signals Robin may be formalizing customer-facing deliverables (checklists / templates / sales scripts) as a separate vault subtree — the IRB application checklist is the first such artifact.

Distributor map refresh (2026-08-07)

Robin uploaded a refreshed b7f52af896c1e3a9.xlsx on 2026-08-07 11:11, producing 8 new *2026-0807.md regional files + a new 全国经销商地图-2026-0807.md index + a new product-association index (_known_associations.md) + a new _meta.json reflecting the 259-dealer tally. The 2026-07-24 baseline (*2026-0724.md × 7 + index) remains in the repo but is now stale.

What changed in the 2026-08-07 baseline vs the 2026-07-24 baseline:

Dimension	2026-07-24 (_meta.json)	2026-08-07 (全国经销商地图-2026-0807.md)
Total dealers	261 (明细表口径)	259 (公司数量汇总)
xlsx sha256	3afd448edcf3a9673848da0de2c554e6a4b22d7329b988695ca242c8bc8c10cf	(re-uploaded with 8-04 同名 + 新增 2-3 家)
Region table	华北 74 / 华东 68 / 华南 62 / 山东 25 / 湖北 19 / 西北 6 / 西南 7	华北 72 / 华东 68 / 华南 62 / 山东 25 / 湖北 19 / 西北 6 / 西南 7
华北 count	74	72 (-2)
Hook 4 output	(none)	4 dealer-management hooks + _known_associations.md

The numeric 261 vs 259 difference is still rooted in the 华北 表 74 vs 汇总 72 discrepancy (two unnamed companies — 序号 63 / 67 — leave the 明细表 2 rows above the 汇总表); the 2026-08-07 baseline carries the same data anomaly plus a new structural artifact: 济南成全生物科技 (曹沛起) is registered in both 华北-2026-0807.md and 山东-2026-0807.md (legitimate cross-region duplicate) — this is the only CelVivo ClinoStar agent in the 259-dealer list and is the thread Robin should follow to close the agent-dong-huiqun-celvivo open question.

_known_associations.md (2026-08-07) — product → dealer mapping

The new index file 02-Clients/Agents/_known_associations.md is the canonical hook-4 output Robin needs to evaluate before the next Chinese-region dealer visit. Key mappings surfaced (5 direct hits):

Product line	261-dealer表 命中	关联客户 / 商机
CelVivo (ClinoStar / ClinoReactor)	济南成全生物科技有限公司 (曹沛起) — registered in both 华北 + 山东 (cross-region, 2 次)	董慧群关联 (待 Robin 确认是否同公司)
FemtoBiomed (CellShot / PROLIVA)	0 direct hits (9X Bio / 汇佰生物 is the direct intermediate, not in the 261 dealer list)	TriArm Therapeutics (翁靖傑, 上海 CGT/CAR-T) — 128 万 Phase1 / 8-10 至 8-14 现场 demo
3Brain (HD-MEA)	0 direct hits	—
Cellink (BIO X)	0 direct hits	—
西南医大 心研所 殴贤红	2 dealers: 成都百乐 (杨军, 钻石级 1亿, Bio-Rad / Sartorius / Oxford Nanopore / Cytek / Leica, 覆盖川渝黔藏) + 成都立德赛 (川渝云贵陕)	(待 Robin 决策)

Hook-4 questions (Robin 优先补全, per _known_associations.md):

1. 董慧群 is which specific technical contact at 济南成全 — or is she at a different CelVivo-代理?
2. 西南医大 殴贤红 → 成都百乐 vs 成都立德赛 — which dealer first?
3. 邓昊伦 (02-Contacts/) 蛇类神经方向 → 3Brain HD-MEA 拜访?
4. 261 dealer 表 has 0 3Brain / Cellink 代理 — is the dealer list incomplete, or does Robin need to actively recruit those dealers?

Log these as a new commitment on /commitments.md (distributor-8-07-association-followup) and as updates to /open-questions.md (the agent-dong-huiqun-celvivo question now partially answered — agency identified but personal contact fields still 待补).

Notable entities surfaced by the vault (structural hints only)

• Quintard 2024 Nat Commun microfluidic vascularized organoid chip (2026-08-16, 7 commits in 48-hour window) — obsidian-vault/Literature/Deep-Reads/Organoid/quintard_2024_vasorganoid_chip.md (189 lines; 4-commit LDR cycle 0fc8db24 adds → 290e9635 -v2 修图床/双 H1/落款 → 24c713de -v3 Wiki.js 自带图床 6 张图 → 4073abf4 -v4 转发语标题/落款加粗/删 3Brain; Wiki IDs 1719/1720/1722, NocoDB Id 3297). The paper is the first microfluidic / organ-on-chip platform paper Robin has deep-read in the 2026-08 window; the platform combines (i) 10-channel parallel microfluidic chips with U-shaped capture sites (300-800 µm adjustable), (ii) fibrin + Matrigel hydrogel layer deposition using Landau-Levich-Bretherton effect, (iii) ~10 s capture efficiency ~100%, (iv) dynamic perfusion 7-30 days with HUVEC + fibroblast co-culture + hiPSC-derived BVO + islet spheroid + lung organoid cross-validation, (v) hierarchical vasculature (37 µm upstream artery-vein + 8 µm BVO capillaries, matching physiological ranges 50-1900 s⁻¹). Net-new external evidence in this run (git-repo-1 2026-08-17). The 4-star "与我们的产品" table lists Mimetas OrganoPlate ⭐⭐⭐⭐ (direct Phaseguide-based vascularized / kidney / intestine organ-on-chip competitor) + CelVivo ClinoStar ⭐⭐⭐ (upstream workflow step: BVO differentiation day 0-15 needs rotating-wall suspension culture; ClinoStar is the canonical hardware for this stage; the paper's day 15 → chip-on-board handoff is the canonical CelVivo → organ-on-chip workflow) + Emulate Organ-Chip ⭐⭐⭐ (Colon-Intestine-Liver platform companion). Synthesis routes into /themes/05-robin-research.md (新增 by-vendor entry) and /sources/literature.md (last-30-days deep-read table). Vendor-anchor mapping: CelVivo-adjacent (workflow upstream) + Mimetas OrganoPlate / Emulate Organ-Chip (organ-on-chip product lane that Robin's portfolio does not currently cover but represents a potential cross-sell if Robin's customers ask "where do I run my CelVivo-matured organoids in a vascularized microenvironment?"). Customer-entry: 药企临床前 (vascularized drug screening) + 微流控 organ-on-chip 平台集成商 (Mimetas / Emulate channel partners) + academic PI (vascular development / diabetes). Track on next fetch whether Robin publishes a /sources/literature-quintard-2024-nat-commun-vasorganoid-chip-deepread.md synthesis page; the deep-read pipeline currently only carries liang-2026-celvivo-clinostar-positioning + miao-2025-celvivo-clinostar-positioning + liu-2026-hd-mea-roadmap-implication + sharma-2026-retinal-organoid-mea-cross-sell — no Quintard synthesis page yet.
• Guo 2026 Front Cell Dev Biol organoid ethics systematic review (2026-08-16, 7 commits in 48-hour window) — obsidian-vault/Literature/Deep-Reads/Organoid/guo_2026_organoid_ethical_review.md (170 lines + 3 真图; 3-commit LDR cycle 2e6f5989 adds → 00f824f2 -v2 修图床 (加 2 张 Wiki.js 自带图) → a4fa5a32 -v3 补 Fig 1; Wiki ID 1724, NocoDB Id 3298). The paper is the first organoid-research ethics / IRB systematic review Robin has deep-read in any window — fills the methodological gap on the IRB-side that the prior clinical-translation evidence (CDE classification + Order No. 818) does not directly cover. The paper structures the IRB review framework as 7 mandatory points (sample provenance + donor informed consent + data privacy & de-identification + co-culture agency + animal welfare 3R + cross-border regulation + long-term storage & termination); the cross-border table compares China (《人类遗传资源管理条例》+ 《涉及人的生命科学和医学研究伦理审查办法》2023), US (HIPAA + Common Rule + NIH GDS), EU (GDPR + Clinical Trials Regulation 536/2014), Japan, Korea. The 4-star "与我们的产品" table lists CelVivo ClinoStar ⭐⭐⭐⭐ (clinical-translation IRB compliance — the 7 mandatory points directly apply to ClinoStar customer IRB submissions; Robin 推广 ClinoStar 给三甲医院时, 可附带本框架作为增值) + Mimetas OrganoPlate ⭐⭐⭐⭐ (co-culture ethics — Mimetas 主营类器官 + 免疫细胞共培养, the co-culture agency framework from Guo 2026 point 4 directly applies) + Emulate Organ-Chip ⭐⭐⭐ (organoid + microfluidic cross-border regulation reference). Net-new external evidence in this run (git-repo-1 2026-08-17). Robin translated the paper into a customer-facing sales ammunition template at templates/类器官IRB申请清单.md (180 lines; 7 mandatory points checklist + 5 customer Q&A + China vs International flow table + 10 attachments + 7 citations; v1.0 dated 2026-08-16, "Robin 8-16 实战沉淀") — see the templates/ entry in the next bullet. Customer-entry: 临床转化型医院 (class A tertiary hospitals running organoid IRB submissions) + 类器官厂家 Robin 培训客户 (the IRB checklist is the canonical "Robin 培训客户 IRB 申请" core material) + academic PI (cross-border collaboration IRB paperwork). Track on next fetch whether (a) the templates/ IRB checklist gets committed, (b) the Robin-author attribution in the template is recognized as a wiki-side customer-training artifact, (c) Robin produces a deep-read synthesis page at /sources/literature-guo-2026-front-cell-dev-biol-organoid-ethics-deepread.md, and (d) the IRB checklist routes into the existing CelVivo industrial-customers program (which currently lives at 05-Documents/Products/Celvivo/Industrial-Customers/) as a standard customer-training artifact.
• Review/ subfolder — first entry (2026-08-13, still uncommitted at 2026-08-17, 4-day carry-forward, watchlist signal weakening) — obsidian-vault/04-Literature/Deep-Reads/Review/zhou2023_computer_vision_microfluidics.md is the first file in a new Review/ subfolder under 04-Literature/Deep-Reads/. The file is untracked at the 2026-08-17 fetch (Robin has not yet committed it — same state as the 2026-08-13 + 2026-08-15 fetches, 0 progress in the 2026-08-13 → 2026-08-17 96-hour window). Watchlist trigger met at this fetch: per the 2026-08-15 watchlist-trigger rubric ("if the file remains uncommitted at the next fetch (2026-08-17 or later), the structural signal weakens"), the Review/ subfolder at the 2026-08-17 fetch is still single-entry, still untracked — the structural signal does weaken at this fetch (4-day carry-forward with no commit, no follow-up paper landed in the subfolder). The Review/ subfolder is more likely to be a one-off than a recurring pattern. The file should either be committed on a future fetch (which would re-strengthen the signal) or remain untracked indefinitely (which would confirm the one-off interpretation). No synthesis routes until the file is committed.
• templates/ subfolder — first entry (2026-08-16, NEW this run) — templates/类器官IRB申请清单.md (180 lines, mtime 2026-08-16, untracked) is the first file in a new templates/ directory at the vault root. The file is Robin's first customer-facing sales ammunition template produced from a single deep-read (the Guo 2026 IRB ethics systematic review). Content: 7 mandatory IRB review points checklist (样本来源/知情同意/数据隐私/共培养主体性/3R 动物福利/跨境监管/长期保存与终止使用) + 5 customer Q&A ("类器官研究要不要 IRB 申请?" / "类器官共培养产品怎么申请 IRB?" / "类器官跨境研究怎么报?" / "3R 原则怎么写?" / "类器官 + 免疫细胞共培养 = CAR-T 体外培养, 算不算新生物体? 伦理上算什么?") + China vs International flow comparison table + 10-row 申请附件清单 + 7 references (Guo 2026 + ISSCR 2021 + OHRP 2016 + GDPR 2018 + China 2023 + China 2019 + Cambridge 2020). The template's version: v1.0 (2026-08-16, Robin 8-16 实战沉淀) and Robin 业务定位: 类器官厂家给三甲医院 IRB 申请的标准模板 + Robin 客户培训材料核心 framing makes it explicit that this is the canonical "Robin 培训客户 IRB 申请" core material. Structural significance: the templates/ directory is new — none of the existing top-level folders (01-Active-Sales/ / 02-Clients/ / 02-Active-Deals/ / 02-Contacts/ / 03-Product/ / 03-Resources/ / 04-Literature/ / 05-Documents/ / 06-Sales/ / 99-Templates/ / memory/) provides a vendor-agnostic customer-training-artifact slot at the vault root. The Obsidian vault already has 99-Templates/ for reusable Obsidian templates (note templates, daily-report templates — per 99-Templates/ size hint 14 .md), but the new templates/ directory is for customer-facing sales ammunition, not Obsidian note templates — a different artifact type. The naming convention overlaps with 99-Templates/ and may need disambiguation; Robin's intent (per the file header) is for this templates/ to be the canonical customer-training artifact directory, distinct from 99-Templates/ Obsidian-note templates. Customer-entry scenarios called out in the template: (a) 类器官厂家研发负责人 = IRB 申请准备, (b) Robin 客户开发 = 培训客户 IRB 申请核心材料, (c) 医院 IRB 委员会 = 类器官研究 IRB 审查标准参考, (d) 学术合作方 = 跨境合作时多国法规差异对照. Carry-forward status (2026-08-17): untracked, future-commit candidate. Track on next fetch whether (a) Robin commits the file to main, (b) more templates land in the directory (extending the customer-training-artifact slot), (c) the templates/ and 99-Templates/ naming overlap gets resolved (rename / docs / conventions). Synthesis routes into /themes/05-robin-research.md (sales ammunition pipeline section).
• celvivo_commercial/ subfolder — first entry (2026-08-17, NEW this run) — celvivo_commercial/1331651_20260630_131201.pdf (56 KB PDF, mtime 2026-08-17, untracked) is the first file in a new celvivo_commercial/ directory at the vault root. The PDF is the existing 6-30 quote PDF that Robin migrated into a new folder. The file is a quote PDF, not a synthesis target — the on-disk evidence is the existing 6-30 quote document that already exists in 05-Documents/Products/Celvivo/Industrial-Customers/ (per the 2026-08-15 synthesis-policy section above, "commercial docs (8 files: Exhibit 1 Price Book / Exhibit 3 SuperUser certification / Huibai demo discount agreement / 惠百 PO 盖章版 / Celvivo Distribution Agreement 2026 Huibai Bio / 1331651_20260630_131201 (6-30 quote) / Packing Slip Ordre 726_1 / Packing Slip Ordre 726_2)"). Structural significance: the celvivo_commercial/ directory is new — Robin has migrated the 6-30 quote out of wherever it was previously (presumably a working folder or 05-Documents/Products/Celvivo/ deep path) into a top-level dedicated directory. The migration is unfinished — only 1 file in the new directory; if Robin intends the directory to consolidate all 8 commercial docs from 05-Documents/Products/Celvivo/Industrial-Customers/, the other 7 files (Exhibit 1 Price Book / Exhibit 3 SuperUser certification / Huibai demo discount agreement / 惠百 PO 盖章版 / Celvivo Distribution Agreement 2026 / Packing Slip Ordre 726_1 / Packing Slip Ordre 726_2) should eventually land here too. No synthesis routes until Robin commits the file or migrates more docs into the directory. Carry-forward status (2026-08-17): untracked, single-entry, future-commit candidate. Track on next fetch whether (a) the file gets committed, (b) more commercial docs migrate into the directory.
• 2026-08-15 sources-sync bug — count-data wipe (operational) — the 2507925e27b83b4f9d2e6f3b9c939d081a90f9f2 chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-15) commit at 2026-08-15 +0800 02:31 committed empty count values for NocoDB / Wiki.js / RAGFlow (SeaFile was already empty so the commit was a no-op there): (a) NocoDB: 6614 → 0 total records, with all 13 per-table counts (brain_organoid_literature / intestinal_organoid_literature / Celvivo_literature / cardiac_organoid_literature / cancer_organoid_literature / liver_organoid_literature / other_organoid_literature / kidney_organoid_literature / retinal_organoid_literature / Cellink_literature / organoid_literature_old / lung_organoid_literature / 3Brain_literature) cleared to empty cells; (b) SeaFile: libraries table unchanged (was empty in 1737454 already — a separate, older cron issue not introduced by 2507925); (c) Wiki.js: 83 → 0 unique pages, ID range 22..1704 → 0..0, Locale 分布 → empty, Top-level 路径分布 → empty; (d) RAGFlow: landing 200 → 000, /api/v1/health 404 → 000, /api/v1/datasets 401 → 000. The header lines on each affected /sources/{nocodb,ragflow,seafile,wikijs}.md page still report 上次同步: 2026-08-14T18:30:42Z (the prior successful sync timestamp), but the body count values are wiped. Probable root cause: the auto-source-sync CRON job ran but the underlying NocoDB / Wiki.js / RAGFlow API calls failed (likely the same operational issue already documented on /sources/web-search.md and /sources/README.md — runtime registry disagreement on enabled: true vs. disabled); the script committed the empty values instead of skipping the commit on failure. Impact: 3 source pages now show misleading zero/null values (NocoDB / Wiki.js / RAGFlow); Tavily / HN / git-repo synthesis is unaffected. Recovery: the wiped data is recoverable from the prior wiki commit (git show 1737454:sources/nocodb.md etc. will restore the pre-wipe state). This run restored the wiped data on all 3 affected pages (plus an operational note documenting the bug) so the wiki is internally consistent again. Wiki-synthesis concern: none — the synthesis layer (themes / commitments / open-questions / personal-logistics) is independent of the source-page counters. Operational concern: yes — the auto-source-sync job should (a) check connectivity before committing, (b) skip the commit on API failure rather than committing empty values, or (c) preserve the prior counter values when a fresh pull returns null/empty. Recorded for traceability here + on each affected /sources/{nocodb,ragflow,seafile,wikijs}.md page.
• Liang 2026 liver organoid fibrosis platform (2026-08-12) — 04-Literature/Deep-Reads/Liver/2026-08-12_Liang_2026_SciRep_liver_organoid_fibrosis_platform.md (170 lines; [[MOC-类器官与3D培养]] already names this paper via related: back-link). The paper is the net-new external evidence this run (git-repo-1 2026-08-12) brought into the vault; see synthesis at /themes/01-organoid-equipment.md § CelVivo evidence (added 2026-08-12) and /commitments.md liang-2026-celvivo-clinostar-positioning. Single-paper LDR cycle: 4 commits (e542c977 → 8699a154 → aacba7aa → 297f106d) walked Robin's standard 3-stage SOP on the same file (186 lines → 105+/122- page 946 rewrite → page 934 修齐 micro-revisions). The 4-star "与我们的产品" table on the paper lists CelVivo ClinoStar ⭐⭐⭐⭐ (P1-P10 长程扩增对应旋转培养 30+ 天无剪切; HSC 静止态在模拟微重力下 7+ 天维持) + CelVivo ClinoReactor ⭐⭐⭐⭐ (单组织 3 轨道分通道灌流; TGFβ 时间程序精确切换) — parallel CelVivo ClinoStar rating 5 to Miao 2025 v2's ClinoStar rating 5 from the 2026-08-08 flywheel-sync, but for liver organoid (long-term maturation + fibrosis modeling) rather than lung organoid (vascularization). 7 SeaFile Fig (Fig1-7) + 4-paper 参考文献 (Huch 2013 / Huch 2015 / Clevers 2016). Customer-entry: 药企临床前 (抗纤维化药筛) + 临床肝活检中心 (1-2 mg → 3 周药敏) + 学术 PI (2D vs 3D 旋转 efficiency). MOC linkage: the paper's related: field already names [[MOC-类器官与3D培养]] (the first MOC, created 2026-08-10) — confirming the MOC pattern is in active use on real deep-reads.
• CelVivo industrial customers program — a dedicated subfolder under 05-Documents/Products/Celvivo/Industrial-Customers/ holds CelVivo_中国工业 客户开发研究报告 (v1 + v2), 客户管线定位_1页图, and 工业客户开发手册-v3. This is a self-contained CelVivo China commercial effort.
• CelVivo sales training cluster — 06-Sales/Content/Training-Materials/ contains a Robin稿生成通字稿 family (v3–v6), a CelVivo赋能培训 PowerPoint family (v1–v9, depth-flavored edits), and a 销售基础话术包 pair. Versions progress from 基础 → 5大管线 → 深度版 → 终稿修正 → 销量仅看.
• 3Brain end-customer dossier set — 11+ dossiers under 03-Resources/End-Customers/ covering 神经所 (上海), 北京大学, 北京天坛医院, 浙大一附院, 中科院昆明动物所, 西南医科大学, 贵州医科大学, plus TCM accounts at 云南中医药大学 and 天津创新中药.
• CelVivo distributor technical contact (2026-07-28, partially resolved 2026-08-07) — 02-Clients/Agents/董慧群.md is the first profile under the 02-Clients/Agents/ bucket (frontmatter type: agent, role: 代理商技术同事, products: CelVivo ClinoStar / ClinoReactor). The 2026-08-07 _known_associations.md index now identifies the CelVivo dealer as 济南成全生物科技 (曹沛起) — the only ClinoStar agent in the 259-dealer list, registered in both 华北 + 山东. Robin still needs to confirm: (a) is 董慧群 the same agency? (b) phone / WeChat / served end-customers / opportunities. The agency-side gap is now closed.
• ITX 24h host build (first observed 2026-07-31; still untracked) — 03-Resources/ITX-24h-Host/ITX_24h_Host_v18_Config_2026-07-31.md is a top-level bucket first observed between the 2026-07-30T18:13 fetch and the 2026-07-31T18:08 fetch; it remains untracked. Single file: Robin's personal 24h server build plan for hosting Hermes Agent + AI workflow stack — mATX + i5-12400 + DDR4-2666 32G + 板载 Realtek 1Gb + Intel PRO/1000 GT 双网卡 NAS 隔离, ¥2,985.82, 10/11 parts arrived, planned hostnames/roles: 192.168.31.100 (主力机 SSH) vs 10.10.10.254 (RAGFlow / NAS RAGFlow API). Workflow-tooling priority LOW (not vendor-anchored), so it does not earn a /themes.md row, but the build remains a source-anchored personal-infra work item and was promoted to /commitments.md as itx-24h-host-build-2026-q3 (Owner: me) for the post-assembly steps (Ubuntu Server 22.04 install + 双网卡静态 IP + Hermes Agent install + 24h soak test).
• Cells + 2026-08-08 cluster — Fernandez Vallone 2026 Cells (hiPSC brain organoids for THSDC chemical screening, NAMs platform) is the first 04-Literature/Deep-Reads/Cells/ entry. New application domain (toxicology + NAMs) compared to the prior Brain / Cancer / Liver buckets. CelVivo + 3Brain application scenarios called out in tags.
• Microbioreactor + 2026-08-07 cluster — Rosero 2026 Front Bioeng Biotechnol Microbioreactor design Mini Review is the first 04-Literature/Deep-Reads/Microbioreactor/ entry. Cross-vendor adjacent (CelVivo ClinoStar / Cellink BIO X / FemtoBiomed CellShot). Landed in NocoDB Robin_Picked_Papers (PMID 42516424, Wiki.js ID 1696).
• Parfitt 2024 Nat Commun (DJ1 LOF midbrain organoid + PD) — untracked file 04-Literature/Deep-Reads/Brain/2026-08-06_Parfitt_GM_et_al_NatCommun_2024_DJ1_LOF_midbrain_organoid_PD.md (15,972 bytes, mtime 2026-08-06). DJ1 LOF through astrocyte lysosomal dysfunction → AGE → α-syn → DA neuron death; CelVivo + 3Brain application scenarios in tags. Not yet on main; pending Robin commit.
• CellSweep — referenced in the wiki goal focus areas; not surfaced as a top-level vault folder in this run, so it likely lives under Work/ or scripts/ (outside the navigation index).
• Phase A metadata batch + first MOC (2026-08-10) — Robin ran a frontmatter-hygiene + MOC-discipline sprint on 2026-08-10: (a) d97b39ed Phase A 批量 standardized 6 deep-read notes with the 6-field frontmatter (doi / journal / year / volume / pages / authors array / pmid) — Organoids 2026 review + CelVivo PAH Metabolomics + Shin 2024 thalamocortical organoids 22q11ds + Fernandez Vallone 2026 Cells THSDC + Liu 2026 NBME shape-conformal organoid + 类器官综述_CMOS_HD_MEA_类器官电生理_2026-06-05; (b) 6b717aef MOC 方案 1 样品 created the first MOC at 04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md (95 lines, 沙牛《AI 时代的 Obsidian 公开课》课时 1 pattern, type: moc) and added related: back-link frontmatter to 7 papers; (c) 3b929c2f wang2024 方案 2 样品 added 7 image alt descriptions on top of the 6-field frontmatter for wang2024-org-on-chip.md. The MOC's own related: list already names [[MOC-3Brain-HD-MEA]] as the next planned MOC, plus [[02-Clients/Agents/_known_associations]] and [[02-Active-Deals/CellShot-TriArm-Demo-计划-v2-老师版-2026-07-20]], so the pattern is expected to extend. None of the changes add new external evidence — the 6 papers already existed on main; this commit set only normalizes their metadata and cross-references. The MOC creation is the first durable structural artifact on the knowledge-graph side and is worth tracking on the next git-repo fetch.

Synthesis policy for this source

• This run (2026-08-17, git-repo-1 18:09Z): 7 new vault commits landed in the 2026-08-15T18:07Z → 2026-08-17T18:09Z window — the vault HEAD bumped from 297f106d (the 2026-08-12 Liang 2026 cluster) to a4fa5a32 (the 2026-08-16 Quintard 2024 + Guo 2026 cluster). The cluster breaks down as: (a) Quintard 2024 Nat Commun 4-commit LDR cycle (0fc8db24 adds 189 lines → 290e9635 -v2 修图床/双 H1/落款 → 24c713de -v3 Wiki.js 自带图床 6 张图 → 4073abf4 -v4 转发语标题/ 落款加粗/删 3Brain) on obsidian-vault/Literature/Deep-Reads/Organoid/quintard_2024_vasorganoid_chip.md; (b) Guo 2026 Front Cell Dev Biol 3-commit LDR cycle (2e6f5989 adds 170 lines → 00f824f2 -v2 修图床 (加 2 张 Wiki.js 自带图) → a4fa5a32 -v3 补 Fig 1) on obsidian-vault/Literature/Deep-Reads/Organoid/guo_2026_organoid_ethical_review.md. The 2026-08-16 cluster is the first time since the 2026-07-28 / 2026-07-29 Parate / Lee / Hodge cluster that two new paper deep-reads landed on main in the same 48-hour window, and the first time a review-type IRB / ethics systematic review (Guo 2026) was deep-read in any vault window. 2 new untracked directories appeared in the working tree this fetch: (a) celvivo_commercial/1331651_20260630_131201.pdf (the 6-30 quote PDF migrated into a new folder); (b) templates/类器官IRB申请清单.md (the IRB application checklist Robin produced from the Guo 2026 review — Robin's first customer-facing sales ammunition template derived from a single deep-read). The 23 untracked working-tree files from the 2026-08-13 fetch are unchanged at this fetch (the Review/zhou2023_computer_vision_microfluidics.md first-entry-in-Review/-subfolder is still untracked, now a 4-day carry-forward with watchlist signal weakening per the Notable-entity entry). Wiki-side: 4 new wiki commits landed (151d22b daily update 2026-08-16 + 997b648 sources-sync 2026-08-16 + 5c70881 daily update 2026-08-17 (created the new sources/openwiki-version-drift.md auto-generated page) + be49285 sources-sync 2026-08-17), advancing HEAD from 2507925 (2026-08-15) to be49285 (2026-08-17). 9 dirty wiki files in the working tree (.last-update.json + quickstart.md + sources/README.md + sources/hackernews.md + sources/nocodb.md
  • sources/ragflow.md + sources/seafile.md + sources/web-search.md
  • sources/wikijs.md) are accumulated synthesis-layer edits from the prior HN-1 2026-08-15 + HN-1 2026-08-16 + HN-1 2026-08-17 + web-search-1 2026-08-15 + web-search-1 2026-08-17 + git-repo-1 2026-08-15 runs that are pending the next CLI orchestration commit (down from 10 dirty files at the 2026-08-15 fetch — sources/index.md got committed in the 151d22b 2026-08-16 daily update). One new wiki file added in the window: sources/openwiki-version-drift.md (auto-generated OpenWiki version drift monitor; reports v0.3.1 local → v0.3.3 npm latest as of 2026-08-15T20:00:03Z with a manual npm install -g openwiki@latest action and a WARNING that v0.3.1 → v0.4+ may have breaking changes; the page is informational, not a synthesis target). No /commitments.md row, no /open-questions.md row, no /personal-logistics.md item added this run beyond the canonical synthesis pipeline — the Quintard 2024 deep-read has no existing synthesis page yet (the deep-read pipeline currently only carries liang-2026-celvivo-clinostar-positioning
  • miao-2025-celvivo-clinostar-positioning + liu-2026-hd-mea-roadmap-implication
  • sharma-2026-retinal-organoid-mea-cross-sell); the Guo 2026 IRB review is the first ethics-side deep-read and the IRB checklist template is the first customer-facing sales ammunition template, both of which warrant a commitment + a synthesis page on a future fetch. Wiki edits this run: (a) /sources/git-repo.md (this page) — refreshed frontmatter HEAD pointers (vault HEAD 297f106d → a4fa5a32, wiki HEAD 2507925 → be49285, tags + 2026-08-17, timestamp → 2026-08-17T18:09:32Z), refreshed the Connector / State section to the new 2026-08-17T18-09-32-895Z raw manifest, refreshed the obsidian-vault working-tree-status section to 2026-08-17 (7 new vault commits, 2 new untracked dirs, the Review/zhou2023_computer_vision_microfluidics.md carries forward as still-untracked), refreshed the Recent-commits-for-vault table to put the 7 new 2026-08-16 commits on top of the 2026-08-12 cluster, refreshed the openwiki-wiki working-tree-status section to 2026-08-17 (4 new wiki commits + 9 uncommitted synthesis-layer edits — sources/index.md got committed in 151d22b), refreshed the Recent-commits-for-wiki table to put the 4 new 2026-08-16/2026-08-17 commits on top of the 2026-08-15 cluster, refreshed the Summary-of-last-48-hours table to add the 2026-08-15T18:07Z → 2026-08-17T18:09Z window data (7 vault commits / 4 wiki commits / 9 uncommitted wiki files / 1 new wiki file + 2 new untracked dirs + 4-day carry-forward on Review/ subfolder), refreshed the Notable-entity section to add (a) "Quintard 2024 microfluidic vascularized organoid chip" entry (with 4-star Mimetas/CelVivo/Emulate mapping), (b) "Guo 2026 organoid ethics systematic review" entry (with 4-star Mimetas/CelVivo/Emulate mapping + IRB checklist template cross-link), (c) refreshed "Review/ subfolder" entry with watchlist-trigger-met note, (d) new "templates/ subfolder" entry (first customer-facing sales ammunition template), (e) new "celvivo_commercial/ subfolder" entry (the 6-30 quote PDF migration), refreshed the Synthesis-policy section with this run's delta summary. No /themes.md row change — the new external evidence routes into the existing class-organoid-3d-bioprinting theme row (Quintard 2024 is organ-on-chip adjacent to Robin's 4 application domains; Guo 2026 is IRB-side adjacent to the same row); the Robin-authored IRB checklist template routes into the existing /themes/05-robin-research.md "Sales ammunition pipeline" section rather than a new theme row. No /open-questions.md row, no /personal-logistics.md item — the IRB checklist is a vendor-anchored customer-training artifact, not a memory-graph uncertainty. (b) /themes/05-robin-research.md — vault-snapshot metadata refreshed (fetch timestamp → 2026-08-17T18:09:32Z, raw-manifest path → the new 2026-08-17T18-09-32-895Z manifest; vault HEAD 297f106d → a4fa5a32; untracked-dir set refreshed with celvivo_commercial/ + templates/ entries; 04-Literature/Deep-Reads/Organoid/ count 659 → 661 (Quintard + Guo); 30-day research output table extended with the 2026-08-16 Quintard 2024 + Guo 2026 row; by-vendor table extended with Microfluidic / organ-on-chip adjacent and Ethics / IRB rows; Sales ammunition pipeline section extended with the templates/类器官IRB申请清单.md IRB checklist template). (c) /themes/01-organoid-equipment.md — Quintard 2024 added to CelVivo evidence anchors (CelVivo ClinoStar rating 3 upstream workflow step) and Guo 2026 added to the Regulatory / China-specific context section (CelVivo ClinoStar rating 4 IRB compliance ammunition; companion to the existing CDE classification
  • Order No. 818 items). (d) /sources/literature.md — Quintard 2024
  • Guo 2026 added to the 30-day deep-read index. (e) /sources/README.md — git-repo last-updated refreshed from 2026-08-15 18:07 UTC to 2026-08-17 18:09 UTC. (f) /quickstart.md — added the "Latest update — git-repo-1 (2026-08-17T18:09Z)" paragraph. Wiki-side: 4 new wiki commits landed (021e929 daily update 2026-08-14 + 6258717 sources-sync 2026-08-14 + 173b58c daily update 2026-08-15 + 2507925 sources-sync 2026-08-15), advancing HEAD from 1737454 (2026-08-13) to 2507925 (2026-08-15). One operational issue was surfaced by 2507925: the 2026-08-15 sources-sync committed empty count values for NocoDB / SeaFile / Wiki.js / RAGFlow (NocoDB 6614 → 0, Wiki.js 83 → 0, RAGFlow landing 200 → 000) — see Notable-entity § "2026-08-15 sources-sync bug" below. 10 dirty wiki files in the working tree (.last-update.json + quickstart.md + sources/README.md + sources/hackernews.md + sources/index.md + sources/nocodb.md + sources/ragflow.md + sources/seafile.md + sources/web-search.md
  • sources/wikijs.md) are accumulated synthesis-layer edits from the prior HN-1 2026-08-13 + HN-1 2026-08-15 + web-search-1 2026-08-15 + this git-repo-1 2026-08-15 runs that are pending the next CLI orchestration commit. Wiki edits this run: (a) /sources/git-repo.md (this page) — refreshed frontmatter HEAD pointers (vault HEAD unchanged, wiki HEAD 1737454 → 2507925, tags + 2026-08-15, timestamp → 2026-08-15T18:07:49Z), refreshed the Connector / State section to the new 2026-08-15T18-07-49-711Z raw manifest, refreshed the obsidian-vault working-tree-status section to 2026-08-15 (no new untracked files; the Review/zhou2023_computer_vision_microfluidics.md carries forward as still-untracked), refreshed the openwiki-wiki working-tree-status section to 2026-08-15 (4 new wiki commits + 10 uncommitted synthesis-layer edits + the count-data wipe surfaced in the Notable-entity section), refreshed the recent-commits table with the 4 new wiki commits on top of the prior 2026-08-13 cluster, refreshed the Summary-of-last-24-hours table with the 2026-08-13 → 2026-08-15 window data (0 vault commits / 4 wiki commits / 10 uncommitted wiki files / operational issue row), refreshed the Notable-entity section to add a "2026-08-15 sources-sync bug" entry + carry-forward note on the Review/ subfolder entry, refreshed the synthesis-policy section with this run's delta summary
  • the operational-issue observation; (b) /themes/05-robin-research.md — vault-snapshot metadata refreshed (fetch timestamp → 2026-08-15T18:07:49Z, raw-manifest path → the new 2026-08-15T18-07-49-711Z manifest); the vault HEAD pointer stays 297f106d (unchanged across both 2026-08-13 and 2026-08-15 fetches); (c) /quickstart.md — added the "Latest update — git-repo-1 (2026-08-15T18:07Z)" paragraph ahead of the current "Latest update — web-search-1 attempted 2026-08-15 skipped" paragraph; demoted the web-search-1 paragraph to a prior-run reference; updated the Backlog git-repo entry to reflect the new wiki HEAD 2507925 + 4 new wiki commits + 10 uncommitted files + the operational issue note. No /commitments.md row, no /open-questions.md row, no /personal-logistics.md item, no /themes.md row change — the vault delta is empty (no new commits, no new untracked files), and the existing 2026-08-12 Liang 2026 commitment / class-organoid-3d-bioprinting theme row already cover the structural evidence.
• Previous run (2026-08-13, git-repo-1 18:08Z): 0 new vault commits in the 24-hour window — the vault HEAD was unchanged at 297f106d (the 2026-08-12 Liang 2026 4-commit LDR cluster remained the most recent vault activity). The only vault-side delta was 1 new untracked file: 04-Literature/Deep-Reads/Review/zhou2023_computer_vision_microfluidics.md — the first entry in a new Review/ subfolder under 04-Literature/Deep-Reads/ (see Notable-entity entry above). 1 noise file (__pycache__/...pyc) was ignored. Wiki-side: 2 new wiki commits landed (8ddc6d9 daily update 2026-08-13 + 1737454 sources-sync 2026-08-13), advancing HEAD from c57ead4 (2026-08-12) to 1737454 (2026-08-13). 8 dirty wiki files in the working tree were synthesis-layer edits from the prior HN-1 2026-08-13 run that landed after 1737454 committed and were pending the next CLI orchestration commit.
• Previous run (2026-08-12, git-repo-1 18:08Z): 4 new vault commits on the same single Liang 2026 Sci Rep liver organoid paper walked through Robin's standard 3-stage LDR cycle (e542c977 adds file → 8699a154 page 946 9 项 SOP 重写版 → aacba7aa + 297f106d page 934 修齐 micro-revisions) — this was the net-new external evidence for that run. Wiki edits at that time are described in the synthesis-policy paragraph above; the canonical synthesis continues to live at /themes/01-organoid-equipment.md, /themes/05-robin-research.md, and /commitments.md liang-2026-celvivo-clinostar-positioning.
• The vault is a knowledge base, not a live signal stream; durable per-document synthesis (paper deep reads, sales scripts, customer files) requires reading individual files, which is delegated to the Hermes skill and RAGFlow.
• Future runs should keep this page structural. Promote a row to a canonical theme only when the connector observes a recurring workflow (e.g. weekly literature digest cadence, sales training iteration pattern) across multiple fetches.
• Process signal worth watching (2026-08-13): (a) New Review/ subfolder signal — Robin added a 20th subfolder under 04-Literature/Deep-Reads/ dedicated to review-type papers, with zhou2023_computer_vision_microfluidics.md as the first entry. If the subfolder accumulates ≥3 entries, this signals a formal review-paper stream is being built separately from the original-research stream; if it stays at 1 entry, it's a one-off. (b) Liang 2026's MOC linkage confirms the MOC pattern is in active use — the paper's related: field already names [[MOC-类器官与3D培养]] (the first MOC, created 2026-08-10) on the day of publication, not a future-state plan. Track on the next git-repo fetch whether more papers acquire MOC related: back-links and whether MOC-3Brain-HD-MEA / MOC-Cellink-BIO-X land. (c) Page 934 修齐 micro-revisions now appear on every new LDR cycle — 297f106d is the second paper (after 381fcbaa OVB-organoids 2026-08-11) where Robin applied the H1 去括号 / 元数据 bold / 📄PDF 文件名 alignment. The pattern appears to be the new standard end-state. (d) Phase A frontmatter batch rollout is still paused (only 6 of ~1,204 deep-reads received the 6-field frontmatter); no progress this run.

Next update

Run openwiki_ingest_connector connectorId=git-repo (or openwiki personal --update) to refresh. Expect HEAD bump, refreshed recentCommits, and updated working-tree status.