chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-07)

2026-08-07 19:05:11 +08:00
49 changed files with 1122 additions and 3510 deletions
@@ -1,5 +1,5 @@
 {
-  "updatedAt": "2026-09-30T18:49:12.236Z",
+  "updatedAt": "2026-08-07T10:43:02.305Z",
  "command": "update",
  "model": "MiniMax-M3",
  "status": "complete",
@@ -1 +0,0 @@
 Has \n?: 0
@@ -1,8 +1,7 @@
 ---
 type: "Reference"
 title: "OpenWiki 现状 + 操作手册 (2026-07-27)"
-description: "Activation status + operations manual for Robin's local OpenWiki knowledge base as of 2026-07-27. Documents 4 active connectors (HN + git-repo + Tavily + RAGFlow) and the per-source sync scripts (HN top+best feeds, Tavily web-search with TAVILY_API_KEY, git-repo Obsidian vault at /home/ldw/workspace, RAGFlow full-text retrieval at 10.10.10.254:9980). Captures the on-disk Gitea commit + push pattern."
+openwiki_generated: true
 tags: [openwiki, operations, manual, activation, 2026-07-27]
 ---
 # OpenWiki 现状 + 操作手册 (2026-07-27)
@@ -1,9 +1,7 @@
 ---
 type: "Reference"
 title: "Commitments"
-description: "Active work tasks, follow-ups, approvals, and scheduled items extracted from sources (web-search, git-repo, literature flywheel-sync, etc.). Personal errands live in /personal-logistics.md instead."
+openwiki_generated: true
 tags: [commitments, work, follow-ups, distributors-2026-08-07-refresh, dong-huiqun-ji-nan-chengquan-link, liang-2026-celvivo-clinostar-positioning, guo-2026-organoid-irb-checklist-rollout, celvivo-app-note-2026-clinostar-vs-orbital-shaker-positioning, aiello-2025-rc-cfd-clinostar-positioning, kim-2025-egain-3d-mea-vs-3brain-positioning, ajongbolo-2025-brain-organoid-review-cluster, tian-2025-epicardium-mtor-cardiac-expansion, tevonian-2026-vascularized-liver-mps-positioning, yang-2026-cardiac-organoid-review-positioning, shen-2026-vascularized-organoid-chinese-review, zhai-2026-skin-organoid-pemphigus-positioning, stewart-2023-ba5-xbb-neurotropic-brain-organoid, aiello-2025-brain-organoid-reproducibility-celvivo, nguyen-2024-jev-g4-australia-brain-organoid, miao-2025-vascularized-lung-gut-celvivo, yan-2024-tmem106b-sars-cov2-brain-organoid, 2026-08-31, 2026-08-25]
 timestamp: 2026-08-31T18:09:00Z
 ---
 # Commitments
@@ -75,153 +73,6 @@ Concrete work tasks, follow-ups, approvals, and scheduled items extracted from G
 - Status: open
 - Notes: Personal-infra work item (workflow-tooling priority LOW), not vendor-anchored — logged here because it is source-anchored to Robin's actual vault work per the brief's commitments.md rule ("only real Robin commitments"). Plan: mATX + i5-12400 + DDR4-2666 32G + 板载 Realtek 1Gb + Intel PRO/1000 GT (¥2,985.82, 10/11 parts on hand). Two 网卡 VLAN: 192.168.31.100 → 主力机 Win 11 SSH, 10.10.10.254 → 主力 NAS RAGFlow. Post-assembly steps: Ubuntu Server 22.04 LTS install, partition `/` (GM7 512G) + `/data` (mSATA 512G), Docker, dual-NIC 静态 IP, 主力机 SSH key 免密, NAS RAGFlow API 接入, 安装 Hermes Agent, 24h 跑功耗 soak test. The host has no vendor-product overlap; not promoted to `/themes.md` row because that index is reserved for recurring workflow signals.
 ### liu-2026-hd-mea-roadmap-implication: verify with 3Brain whether the Liu 2026 shape-conformal framework is on their product roadmap
 - Owner: me
 - Source: literature flywheel-sync 2026-08-08 — Liu N et al. (2026) Nature Biomedical Engineering, DOI 10.1038/s41551-026-01620-y, Wiki.js Id 1692, NocoDB row 1 in **new table `Robin_Picked_Papers`** (created 2026-08-08, table_id `mbjo0wb56qv1qly`), SeaFile PDF https://fb.biokingdom.top/f/6da50240729e41bdb369/?dl=1. Deep-read synthesis at [`/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md`](/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md)
 - Due: unscheduled
 - Status: open
 - Notes: **Highest product-relevance cluster of today's flywheel-sync**: HD-MEA rating 5 (3000-8000 channels vs current 3Brain Accura-3D 4096; >90% surface coverage vs 5-15% bottom-only), 3D bioprinting microlattice rating 5 (Cellink BIONOVA X / Lumen X cannot directly print at this resolution today but the field direction is clear), patient-derived organoid drug screening rating 5 (first long-term high-throughput electrophysiology drug screening platform — weeks-long stable recording + epilepsy + AD disease modeling). Robin should sell 3Brain's current 4096-electrode Accura-3D as the existing best-in-class AND track whether 3Brain has a flexible-electronics / shape-conformal framework on their roadmap. Companion question on `/open-questions.md`: `liu-2026-rogers-lab-vs-3brain-relationship` (is there any partnership / licensing / competitive pressure between Rogers Lab and 3Brain?). Companion commitment to verify with Cellink: `liu-2026-cellink-microlattice-positioning` (whether BIONOVA X or Lumen X can fabricate flexible-electronics-compatible microlattices).
 ### miao-2025-celvivo-clinostar-positioning: fold Miao 2025 vHLPO co-differentiation story into CelVivo ClinoStar sales narrative
 - Owner: me
 - Source: literature flywheel-sync 2026-08-08 — Miao Y et al. (2025) Cell v2, DOI 10.1016/j.cell.2025.05.041, PMID 40592324, Wiki.js Id 1681, NocoDB row 93, SeaFile PDF https://fb.biokingdom.top/f/24704d54a95941449e2e/?dl=1. Deep-read synthesis at [`/sources/literature-miao-2025-cell-vascularization-v2-deepread.md`](/sources/literature-miao-2025-cell-vascularization-v2-deepread.md)
 - Due: unscheduled
 - Status: open
 - Notes: **Strongest CelVivo ClinoStar product relevance rating (5) in any of the 3 new flywheel-sync papers** — the vHLPO single 3D EB co-induction (mesoderm+endoderm) protocol depends on 3D EB self-organization in low-shear rotating culture, which is exactly what ClinoStar provides. vHLPO 7% ECs vs traditional HLPO 0% is a clinically-meaningful differentiator that no competing 2D / static culture can match. Sales ammunition: "your lung organoid model is missing 100% of vasculature — ClinoStar co-differentiation gives you 7% ECs vs 0%". Cross-vendor co-marketing: CelVivo ClinoStar (culture) + Cellink BIO X (decellularized lung scaffold) + 3Brain HD-MEA (functional readout on the neural mesenchyme). Robin should fold this into the CelVivo industrial-customers program (existing `CelVivo_中国工业客户开发研究报告` v1 + v2 in vault) and pitch to pediatric-hospital pharma R&D accounts (FOXF1 ACDMPV rare disease).
 ### liang-2026-celvivo-clinostar-positioning: fold Liang 2026 长程成熟 + 体外纤维化模型 story into CelVivo ClinoStar / ClinoReactor sales narrative
 - Owner: me
 - Source: git-repo-1 2026-08-12 (vault commit cluster `e542c977` → `8699a154` → `aacba7aa` → `297f106d`) — Liang Y, Ye Y, Xie H, Lui VCH, Chen Y, Tam PKH. (2026) *Scientific Reports* DOI 10.1038/s41598-026-42990-2, PMID 41857098; Wiki.js Id 1716, NocoDB Id 770; SeaFile PDF https://fb.biokingdom.top/f/9d53cfaaa88a45b49b72/?dl=1 + 7 真图 (Fig1-7); vault path `04-Literature/Deep-Reads/Liver/2026-08-12_Liang_2026_SciRep_liver_organoid_fibrosis_platform.md` (170 lines; 4-commit LDR cycle)
 - Due: unscheduled
 - Status: open
 - Notes: **Parallel CelVivo ClinoStar rating 4 + ClinoReactor rating 4 to the existing `miao-2025-celvivo-clinostar-positioning`** but for **liver organoid (long-term maturation + fibrosis modeling)** rather than lung organoid (vascularization). Single tissue 3-轨道 (Hep-Orgs + Cho-Orgs + HSC) → DAPT (Notch 抑制) + Dexamethasone for **P1-P10 长程稳定成熟** (single DAPT only sustains P5; DAPT+Dex 协同才实现 P10) → TGFβ 5-7 day activation of qHSC → aHSC (Acta2/Col1a1 上调) → aHSC 共培养诱导 Hep-Orgs **EMT (Snail/Twist/Vimentin ↑; ALB/CK8 ↓; Lgr5/EpCAM ↓; Ki67 ↓)** = **体外肝纤维化模型**. Sales ammunition: "你的肝类器官只能短期培养? DAPT+Dex P1-P10 稳定成熟 + 单组织 3 轨道 + 14 天纤维化模型 — ClinoStar + ClinoReactor 一站搞定"; paired with "你的抗纤维化药筛需要 14+ 天 3D 多细胞模型 — ClinoReactor 6 通道一次测 6 药". Cross-vendor co-marketing: **CelVivo ClinoStar (P1-P10 旋转扩增) + CelVivo ClinoReactor (3 轨道分通道灌流 + TGFβ 时间程序精确切换) + 3Brain HD-MEA (肝-神经互作延伸, 胆碱能投射场景)**. Customer entry: (a) 药企临床前 — 抗纤维化药筛 14+ 天 3D 多细胞模型 (traditional 2D 或单细胞模型失真); (b) 临床肝活检中心 — 1-2 mg 组织 → 3 轨道 → 3 周内药敏测试 (患者来源 anti-fibrosis drug sensitivity); (c) 学术 PI — 2D 静态分化效率低 → 3D 旋转培养效率提升 2-3 倍. Robin should fold this into the CelVivo industrial-customers program (existing `CelVivo_中国工业客户开发研究报告` v1 + v2 in vault) alongside the Miao 2025 vHLPO entry — these two papers together give a liver + lung CelVivo ClinoStar sales narrative with no 3D-bioprinting vendor dependency. The paper's `related:` field already names `[[MOC-类器官与3D培养]]` (the 2026-08-10 first MOC) — confirms the MOC pattern is in active use on real deep-reads on the day of publication.
 ### robin-picked-papers-nocodb-table: capture the structural change — new NocoDB table for Robin-handpicked papers
 - Owner: me
 - Source: literature flywheel-sync 2026-08-08 — Liu 2026 is the **first entry** in the new NocoDB table `Robin_Picked_Papers` (table_id `mbjo0wb56qv1qly`), created 2026-08-08 per Robin instruction to capture papers Robin hand-picks / provides outside the regular PubMed triage. The table is separate from the existing `Organoid_Literature` table.
 - Due: unscheduled
 - Status: open
 - Notes: The new table has 9 fields: Title, DOI, Journal, Year, Authors, Source, wiki_url, pdf_url, deep_read_summary. Future handpicked papers should land in this table rather than in `Organoid_Literature` (which is PubMed-triage-driven). Verify with Robin: (a) what is the workflow for capturing a handpicked paper — manual PDF drop to `/home/ldw/.hermes/cache/documents/` and then trigger the LDR pipeline; (b) should the LDR pipeline auto-route by signal (PubMed triage vs handpicked), or does Robin always provide the routing signal.
 ### dong-huiqun-ji-nan-chengquan-link: confirm whether 董慧群 is a 济南成全生物科技 技术同事, and route 卸慧群档案 accordingly
 - Owner: me
 - Source: git-repo 2026-08-08 — `02-Clients/Agents/_known_associations.md` (commit `4b237a82`, Hermes Agent 2026-08-07 hook 4) maps 济南成全生物科技有限公司 (曹沛起) as the **only CelVivo ClinoStar-listed agent** in the 259-dealer China map (华北 + 山东 跨区重复登记). `02-Clients/Agents/董慧群.md` (2026-07-28 commit `21491578`) lists 董慧群 as CelVivo 产品技术同事 with `agency: 待补`.
 - Due: unscheduled
 - Status: open
 - Notes: The 2026-08-07 hook 4 partial-resolution gave a likely candidate (济南成全生物科技 曹沛起 company) but the precise link to 董慧群 (and whether she is 济南成全的技术同事, or another dealer) is still unverified. Action: Robin to verify with 董慧群 directly via WeChat / 微信 (current open-question [`/open-questions.md`](/open-questions.md) `agent-dong-huiqun-celvivo`). Once confirmed: update `02-Clients/Agents/董慧群.md` frontmatter `agency` field, and update [`/sources/agents.md`](/sources/agents.md) "代理商品牌" column from "待补" to "济南成全生物科技 (曹沛起)". Until this is done, 董慧群's role in the 济南成全 book of business is unconfirmed.
 ### distributors-2026-08-07-refresh: 落地 2026-08-07 全国经销商地图到 wiki + 跨工具
 - Owner: me
 - Source: git-repo 2026-08-08 — Obsidian vault `02-Clients/Agents/全国经销商地图-2026-0807.md` + 7 区域分文件 (8-07 baseline, 259 dealers across 7 regions, net change -2 from 2026-07-24 baseline). Vault raw survives 2026-08-08 fetch as untracked files (commit `4b237a82` Lin Yongli "4 个经销商管理 Hook 升级").
 - Due: unscheduled
 - Status: open
 - Notes: 8-07 baseline differs from 7-24 baseline in: (a) total 261 → 259 (华北 74 → 72); (b) 济南成全生物科技有限公司 (曹沛起) cross-region registration (华北 + 山东); (c) new `_known_associations.md` index maps CelVivo → 济南成全 / FemtoBiomed → 9X Bio → TriArm / 3Brain + Cellink → 0. Cross-reference: [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md) has been updated to the 8-07 baseline + new associations table; [`/sources/agents.md`](/sources/agents.md) still needs the 董慧群 → 济南成全 link; [`/commitments.md`](/commitments.md) has follow-up for 成都百乐 vs 成都立德赛 decision (open-question `chengdu-baile-vs-lidesai-for-ou-xianhong`). End-customer coverage for 3Brain / Cellink / FemtoBiomed still 0 in the 259 baseline — see open-question `distributors-3brain-cellink-zero-coverage`.
 ### guo-2026-organoid-irb-checklist-rollout: commit IRB application checklist template + add Guo 2026 deep-read synthesis page + fold into CelVivo industrial-customers program
 - Owner: me
 - Source: git-repo-1 2026-08-17 — vault commit cluster `2e6f5989` → `00f824f2` → `a4fa5a32` (Guo Z & Zhang N 2026 Front Cell Dev Biol organoid IRB / ethics systematic review, Wiki.js ID 1724, NocoDB Id 3298, DOI 10.3389/fcell.2026.1721946) + new untracked `templates/类器官IRB申请清单.md` v1.0 (180 lines, Robin 8-16 实战沉淀, derived from the Guo 2026 paper)
 - Due: unscheduled
 - Status: open
 - Notes: **First customer-facing template produced from a single deep-read** in Robin's vault — the IRB application checklist is the canonical "Robin 培训客户 IRB 申请" core material for class A tertiary hospitals running organoid IRB submissions. The 7 mandatory points + 5 customer Q&A + China vs International flow table + 10 attachments + 7 citations map directly to the CelVivo ClinoStar clinical-translation sales narrative (Guo 2026 lists CelVivo ClinoStar ⭐⭐⭐⭐ for IRB compliance ammunition). **Three follow-ups needed**: (a) **commit** `templates/类器官IRB申请清单.md` to `main` (currently untracked); (b) add a wiki-side deep-read synthesis page at `/sources/literature-guo-2026-front-cell-dev-biol-organoid-ethics-deepread.md` mirroring the pattern at `/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md`; (c) fold the IRB checklist into the existing `05-Documents/Products/Celvivo/Industrial-Customers/` CelVivo commercial docs subtree (or, if the `templates/` folder convention holds, fold it into the new `templates/` vault subtree instead — see Robin decision). Companion commitment to fold into Chinese customer IRB conversations: the checklist covers China《人类遗传资源管理条例》+ 《涉及人的生命科学和医学研究伦理审查办法》2023 — directly applicable to the next Class A tertiary hospital Robin visits for CelVivo or 3Brain training.
 ### celvivo-app-note-2026-clinostar-vs-orbital-shaker-positioning: fold the head-to-head shear-stress comparison into ClinoStar sales narrative + CelVivo赋能培训
 - Owner: me
 - Source: git-repo-1 2026-08-24 — vault commit `fb017e4f` (CelVivo Application Note 2026 shear stress ClinoStar vs orbital shaker, Wiki.js 1747, sourced from RAGFlow CelVivo KB 1555e5b2..., Robin 8-24 上传; vault path `obsidian-vault/04-Literature/Deep-Reads/CelVivo_Shear_Stress_AppNote_2026.md`, 10,145 bytes, single-shot LDR entry)
 - Due: unscheduled
 - Status: open
 - Notes: **Canonical ClinoStar vs-orbital-shaker competitive-killer document** — the App Note establishes head-to-head comparison of ClinoStar® vs orbital shaker for 3D 类器官/球体培养 (HepG2/C3A 15-day + embedded Caco-2 肠 + brain organoid) with 3 bio-replicates per condition. Core findings: (a) **low shear stress ClinoStar preserves cytoskeletal integrity** — phalloidin/DAPI 染色 shows ClinoStar F-actin 排列规则 + 形态紧凑 + 细胞间内聚性强 vs orbital shaker F-actin 散布 + 形态松散 + 内聚性下降 (4x + 20x dual magnification); (b) **15-day standardized workflow** — same source cells + same pre-conditioning + same end-point assays; (c) **multi-model transferability** — embedded Caco-2 + brain organoid both show ClinoStar advantage → vendor claim "low shear stress sensitive cell class (肝/肠/脑来源)" validated across 3 model systems. **Highest commercial-relevance paper of the 2026-08-23 LDR cluster** — Robin's first **vendor App Note deep-read** (vs prior primary research + review only). Sales ammunition: "你的 orbital shaker 培养球体 F-actin 散布 + 内聚性下降 — ClinoStar 旋转培养保持细胞骨架完整 + 形态紧凑 — 15 天数据 + 3 bio-replicate 标准流程 + 3 类细胞模型 (HepG2 + Caco-2 + brain organoid)". Companion to existing `celvivo-clinoreactor-thewell-bioscience-xeno-free` commitment. Follow-ups: (a) fold the App Note into `06-Sales/Content/Training-Materials/` (the existing CelVivo赋能培训 v1-v9 cluster could absorb the head-to-head comparison data as a new PPT module); (b) add a wiki-side deep-read synthesis page at `/sources/literature-celvivo-shear-stress-appnote-2026-deepread.md`; (c) confirm with CelVivo whether this App Note is officially sanctioned for Robin's China customer use.
 ### aiello-2025-rc-cfd-clinostar-positioning: fold the < 20 mPa quantitative CFD number into CelVivo ClinoStar sales narrative
 - Owner: me
 - Source: git-repo-1 2026-08-24 — vault commit `f2118a62` (Aiello & Bagni 2025 biorxiv preprint Rotating Chamber brain organoid CFD, Wiki.js 1746, the EMBO Reports submission version `Aiello_Bagni_EMBO R_050325`, Robin 8-24 从 CelVivo KB 找到的 PDF; vault path `obsidian-vault/04-Literature/Deep-Reads/Aiello_Bagni_2025_biorxiv_Brain_Organoid_Fluid.md`, 11,731 bytes, single-shot LDR entry)
 - Due: unscheduled
 - Status: open
 - Notes: **First CFD-quantified Rotating Chamber (RC) low-shear-stress study** in Robin's deep-read set — the paper quantifies what prior ClinoStar marketing material only described qualitatively. Core finding: **COMSOL Multiphysics 6.2 CFD simulation shows cavity shear stress < 20 mPa** (extremely low vs. standard stirred/shaken systems) — the **first quantitative number** for RC shear-stress field. Multi-density validation: relative density 1010/1020/1030 vs medium 1000 confirms shear-stress uniformity across density range + 0-300 objects all experience stable low shear. Morphological CV < 15% across batches + cell lines vs static culture CV > 30%. Cortical cell type recapitulation (SOX2/Nestin/PAX6 + DCX + TBR1/SATB2/MAP2 multi-marker IHC) + scRNA-seq OXPHOS metabolic profiling. **Vendor-anchor mapping**: Aiello paper is **CelVivo ClinoStar-adjacent** (uses RC system which is the ClinoStar simplified geometry) + 3Brain HD-MEA-adjacent (cortical organoid electrophysiology read-out). Sales ammunition: "你的类器官培养系统剪切力是多少? 静态培养 = 不均匀; orbital shaker = 不均匀; ClinoStar 旋转腔 = **< 20 mPa (CFD 量化)** + 跨密度一致 + 跨批次形态变异 < 15%". The < 20 mPa number is **direct ammunition** for the existing ClinoStar ⭐⭐⭐⭐ vendor-positioning pitch — no prior paper in Robin's deep-read set provides the quantitative CFD number. Follow-ups: (a) add a wiki-side deep-read synthesis page at `/sources/literature-aiello-2025-biorxiv-brain-organoid-fluid-deepread.md`; (b) fold the < 20 mPa number into the ClinoStar industrial-customers program alongside the Miao 2025 vHLPO + Liang 2026 liver organoid entries.
 ### kim-2025-egain-3d-mea-vs-3brain-positioning: track the next-gen HD-MEA field consolidation (Liu 2026 Rogers Lab + Kim 2025 EGaIn + 3Brain Accura-3D)
 - Owner: me
 - Source: git-repo-1 2026-08-24 — vault commit `5f02489a` (Kim E, Jeong E, Hong YM et al. 2025 Nat Commun liquid-metal 3D MEA, DOI 10.1038/s41467-024-55752-3, Wiki.js 1744; vault path `obsidian-vault/04-Literature/Deep-Reads/Kim_2025_NatCommun_Liquid_Metal_3D_MEA.md`, 13,567 bytes, single-shot LDR entry)
 - Due: unscheduled
 - Status: open
 - Notes: **3 distinct next-gen HD-MEA approaches now in Robin's deep-read set**: (a) **Liu 2026 Nat Biomed Eng** (Rogers Lab flexible-electronics shape-conformal framework, 3000-8000 channels per organoid, >90% surface coverage) — see existing `liu-2026-hd-mea-roadmap-implication` commitment; (b) **Kim 2025 Nat Commun** (EGaIn liquid-metal 3D pillar MEA, 25-310 μm pillar height, 14 μm diameter, parylene-C selective encapsulation, Ni magnetic layer for shape reconfiguration); (c) **3Brain Accura-3D** (rigid CMOS, 4096 electrodes, planar). The Kim paper is **3Brain HD-MEA competitor / adjacent paper** — Kim's EGaIn 3D MEA is a next-generation flexible 3D MEA approach that is **adjacent to but not directly competing with** 3Brain's rigid Accura-3D chip. Vendor-anchor mapping: Kim paper pairs with Liu 2026 to anchor the **next-gen HD-MEA field consolidation narrative** that Robin's existing `liu-2026-hd-mea-roadmap-implication` commitment tracks. Robin should pitch 3Brain's current 4096-electrode Accura-3D as the **existing best-in-class** AND track whether 3Brain has a flexible-electronics / EGaIn-3D-pillar framework on their roadmap. Follow-ups: (a) add a wiki-side deep-read synthesis page at `/sources/literature-kim-2025-nat-commun-liquid-metal-3d-mea-deepread.md`; (b) update the `liu-2026-hd-mea-roadmap-implication` commitment's Notes to reference Kim 2025 as the second corroborating evidence point (Liu + Kim = 2 distinct next-gen approaches); (c) verify with 3Brain whether the EGaIn / flexible-electronics / shape-conformal directions are on their 2026-2027 product roadmap.
 ### ajongbolo-2025-brain-organoid-review-cluster: pair with Organoids 2026 review to anchor brain-organoid review lane
 - Owner: me
 - Source: git-repo-1 2026-08-24 — vault commit `ad4abcde` (Ajongbolo AO, Langhans SA 2025 Cells brain organoid + assembloid review, DOI 10.3390/cells14110842, Wiki.js 1743; vault path `obsidian-vault/04-Literature/Deep-Reads/Ajongbolo_2025_Cells_Brain_Organoids_Review.md`, 11,367 bytes, single-shot LDR entry)
 - Due: unscheduled
 - Status: open
 - Notes: **Canonical brain organoid + assembloid review** for Robin's deep-read set — the paper establishes a **3-tier taxonomy** (whole-brain → region-specific → complex systems) + **4-class characterization methodology** (morphological + biochemical + functional + omics) + disease-modeling boundaries (neurodevelopmental / neurodegenerative / brain-tumor) + drug-discovery HTS pipeline. **First comprehensive brain-organoid review** in Robin's deep-read set since the 2026-07-29 Organoids 2026 review (`10.1186_s40164-026-00743-x`, vault path `04-Literature/Deep-Reads/Organoid/2026-07-29_Organoids_disease_modeling_treatment_2026_review.md`). Pairs with that review to anchor the **brain-organoid review-paper lane**. Vendor-anchor mapping: **CelVivo ClinoStar-adjacent** (long-term stable brain organoid culture) + 3Brain HD-MEA-adjacent (functional electrophysiology read-out via MEA in the 4-class characterization methodology). Follow-ups: (a) add a wiki-side deep-read synthesis page at `/sources/literature-ajongbolo-2025-cells-brain-organoids-review-deepread.md`; (b) cross-link the Ajongbolo synthesis page with the existing Organoids 2026 review entry on `/themes/05-robin-research.md` review-paper cluster; (c) consider promoting the brain-organoid review lane to a `/themes.md` row if a 2026-08-25 fetch surfaces another brain-organoid paper.
 ### tian-2025-epicardium-mtor-cardiac-expansion: track cardiac epicardium lane for potential CDMO/regenerative-medicine opportunities
 - Owner: me
 - Source: git-repo-1 2026-08-24 — vault commit `40b357b8` (Tian Y, Lucena-Cacace A, Tani K et al. 2025 Nat Commun hiPSC epicardium mTOR maturation, DOI 10.1038/s41467-025-60934-8, Wiki.js 1745; vault path `obsidian-vault/04-Literature/Deep-Reads/Tian_2025_NatCommun_Epicardium_mTOR.md`, 15,578 bytes, single-shot LDR entry)
 - Due: unscheduled
 - Status: open
 - Notes: **First cardiac-epicardium paper in Robin's deep-read set** — Tian paper establishes **Torin1 (dual mTORC1/2 inhibitor, 200 nM) drives hiPSC epicardium maturation** with mature markers (TJP1/WT1/TBX18/ALDH1A2/CDH18) up + EMT markers down + proliferation markers down + fatty-acid metabolism maturation; 379 DEGs; adult-like profile vs GSE84085; YBX3 + MAFF identified as Torin1-specific TFs; **paracrine TNNI3 upregulation in hiPSC ventricular cardiomyocyte EBs co-cultured for 10 days** (epicardium-to-cardiomyocyte maturation cross-talk). **Application domain**: cardiac organoid regeneration — fits the broad cardiac application-domain bucket that Robin's wiki scope covers. **No vendor callouts in the deep-read** (no CelVivo / 3Brain / Cellink / FemtoBiomed product rating) but the paracrine cross-talk finding is a candidate for cross-vendor positioning if Robin pitches cardiac-regeneration programs to pharma R&D or CDMO accounts. The 15,578-byte size is the **largest** of the 5 new LDR files — reflects Robin's deep-dive on the mTOR pathway mechanism. Follow-ups: (a) add a wiki-side deep-read synthesis page at `/sources/literature-tian-2025-nat-commun-epicardium-mtor-deepread.md`; (b) verify whether any active Chinese pharma R&D / CDMO / regenerative-medicine account maps to the cardiac-epicardium lane (the active CRM profile set is mostly CelVivo / 3Brain neural-organoid focused — no cardiac-epicardium customer dossier surfaced yet); (c) consider whether Robin should fold cardiac into the existing `/themes/01-organoid-equipment.md` theme or open a new `theme-cardiac-regeneration.md` if cardiac papers recur.
 ### tevonian-2026-vascularized-liver-mps-positioning: Tevonian 2026 Nat Commun vascularized liver MPS vendor-mapping + 中国药企 hepatic-IR 药筛 positioning
 - Owner: me
 - Source: git-repo-1 2026-08-25 — vault commit `089177a7` (Tevonian et al. 2026 Nat Commun vascularized liver microphysiological system, PMID 41634021, DOI 10.1038/s41467-025-68031-6; vault path `obsidian-vault/04-Literature/Deep-Reads/Vascularized-Organoids/Tevonian_2026_Nat_Commun_Vascularized_Liver_MPS.md`, **first file in new `Vascularized-Organoids/` subfolder**)
 - Due: unscheduled
 - Status: open
 - Notes: **First vascularized liver MPS paper** in Robin's deep-read set; **5-vendor product mapping retrofit applied** via the `9aa2af4c` post-publish retrofit commit (CelVivo ClinoStar / ClinoReactor + Cellink BIO X + Mimetas OrganoPlate + 3Brain HD-MEA + FemtoBiomed CellShot). Mimetas OrganoPlate is the canonical microphysiological system for the multi-channel vascularized liver architecture (PDMS + fibrin + primary hepatocytes + HUVEC) + CelVivo ClinoReactor for upstream hepatocyte maturation (Hep-Orgs source) + Cellink BIO X for the decellularized liver scaffold matrix. **Application domain**: vascularized liver MASLD/NASH 体外建模 + 个性化药筛 + 血管化类器官平台. Companion to the existing **Liang 2026** liver organoid entry (ClinoStar ⭐⭐⭐⭐ for P1-P10 long-term maturation + ClinoReactor ⭐⭐⭐⭐ for 3-track HEP/CHO/HSC perfusion) — Tevonian 血管化 dimension extends the existing Liver/ subfolder's fibrotic disease modeling story. Follow-ups: (a) add a wiki-side deep-read synthesis page at `/sources/literature-tevonian-2026-nat-commun-vascularized-liver-mps-deepread.md`; (b) cross-link Tevonian with Shen 2026 in the new Vascularized-Organoids/ subfolder to anchor a vascularized-organoid review-paper cluster; (c) verify whether the active MASLD/NASH hepatic-IR account dossier (if any in the CRM) maps to Mimetas OrganoPlate CelVivo ClinoReactor + Cellink BIO X as a triple-vendor solution.
 ### yang-2026-cardiac-organoid-review-positioning: Yang 2026 Stem Cell Res Ther cardiac organoid review vendor-mapping + 心脏药物毒性测试 positioning
 - Owner: me
 - Source: git-repo-1 2026-08-25 — vault commit `583859a8` (Yang L et al. 2026 Stem Cell Res Ther cardiac organoid review, PMID 41963991, DOI 10.1186/s13287-026-04996-5; vault path `obsidian-vault/04-Literature/Deep-Reads/Cardiac-Organoids/Yang_2026_Stem_Cell_Res_Ther_Cardiac_Organoid_Review.md`, **first file in new `Cardiac-Organoids/` subfolder**)
 - Due: unscheduled
 - Status: open
 - Notes: **First comprehensive cardiac organoid review** in Robin's deep-read set; **5-vendor product mapping retrofit applied** via the `9aa2af4c` post-publish retrofit commit (same 5-vendor mapping as Tevonian). Companion to **Tian 2025 Nat Commun** (the cardiac epicardium mTOR paper from the 2026-08-23 burst) which established the actual mechanistic depth — Yang 2026 is the canonical review that contextualizes Tian alongside the prior cardiac organoid literature (hPSC cardiac organoid generation methods, maturation protocols, disease modeling applications, regenerative medicine routes). Covers FGF/PI3K/Wnt/BMP/Activin/RA 五大信号通路 + 三种 3D 培养策略. **Application domain**: cardiac organoid — Robin expands from the prior 2-paper Cardiac/ subfolder to a dedicated Cardiac-Organoids/ subfolder; first time Robin has opened a new subfolder explicitly for an application-domain cluster. **Robin 业务对接**: 心脏药物毒性测试 + hiPSC 衍生心脏类器官服务 + 心血管疾病建模. Follow-ups: (a) add a wiki-side deep-read synthesis page at `/sources/literature-yang-2026-stem-cell-res-ther-cardiac-organoid-review-deepread.md`; (b) pair Tian + Yang as a paired mechanistic + review cluster on `/themes/05-robin-research.md`; (c) verify whether any active Chinese pharma R&D cardiac-toxicology account maps to CelVivo + 3Brain as a paired vendor solution for hiPSC-derived cardiac organoid electrophysiology.
 ### shen-2026-vascularized-organoid-chinese-review: Shen 2026 Chin Med J vascularized organoid systematic review for Chinese-hospital IRB positioning
 - Owner: me
 - Source: git-repo-1 2026-08-25 — vault commit `5907cdfc` (Shen Y et al. Chin Med J 2026 vascularized organoids systematic review, PMID 42268296, DOI 10.1097/CM9.0000000000004136; vault path `obsidian-vault/04-Literature/Deep-Reads/Vascularized-Organoids/Shen_2026_Chin_Med_J_Vascularized_Organoids_Review.md`, Chinese-language peer-reviewed systematic review from 华西医院, second file in new Vascularized-Organoids/ subfolder)
 - Due: unscheduled
 - Status: open
 - Notes: **Chinese-language peer-reviewed vascularized organoid systematic review** — establishes credential Chinese-hospital-academic source for Robin's active Chinese pharma R&D / CDMO customer base. Structures vascularized organoid 4 大策略 (共培养 + 转录因子诱导 + 微流控 + 生物材料支架) + 12 维对比 + 三大未来方向. **Vendor anchor mapping**: TBD — not retrofitted by `9aa2af4c` (only Tevonian + Yang got the 5-vendor retrofit). **Application domain**: vascularized organoid — adds a 2-paper cluster to the new Vascularized-Organoids/ subfolder. The Shen 2026 review is the **review-paper anchor** and Tevonian 2026 is the **research-paper anchor**. **Robin 业务对接**: 血管化类器官服务 + 多层血管网络平台 + 个性化精准医疗. Follow-ups: (a) add a wiki-side deep-read synthesis page at `/sources/literature-shen-2026-cmj-vascularized-organoids-review-deepread.md`; (b) cross-link with Tevonian 2026 to anchor a vascularized-organoid review-paper cluster; (c) verify whether the Chinese-language source yields any CelVivo-specific IRB or vascularization positioning material for Chinese-hospital customer conversations.
 ### zhai-2026-skin-organoid-pemphigus-positioning: Zhai 2026 Sci Adv 3D skin pemphigus autoimmune dermatology positioning
 - Owner: me
 - Source: git-repo-1 2026-08-25 — vault commit `9d4767c7` (Zhai T et al. Sci Adv 2026 3D skin pemphigus, PMID 41512055, DOI 10.1126/sciadv.adz5003; vault path `obsidian-vault/04-Literature/Deep-Reads/Skin-Organoids/Zhai_2026_Sci_Adv_3D_Skin_Pemphigus.md`, **first file in new `Skin-Organoids/` subfolder**, **net-new application domain** — autoimmune dermatology + 3D skin)
 - Due: unscheduled
 - Status: open
 - Notes: **First 3D-skin organoid disease-modeling paper** in Robin's deep-read set; **net-new application domain** (autoimmune dermatology + 3D skin) that Robin's existing ~22 deep-read subfolders do not cover. Uses **3D 打印 + 自组织多层血管化皮肤模型** to model 天疱疮 (pemphigus) autoimmune disease + EGFR 靶向治疗 + ML 辅助药筛. **Vendor anchor mapping**: TBD — Zhai paper does NOT have the `9aa2af4c` retrofit 5-vendor mapping (only Tevonian + Yang got the retrofit). Skin organoid is a candidate workflow for **CelVivo ClinoReactor** (long-term 3D skin culture — similar to the existing liver, brain, lung, retinal organoid applications) but the Sci Adv paper's specific ClinoReactor / ClinoStar callouts are not in the manifest entry. **Application domain**: 3D skin organoid + autoimmune dermatology (pemphigus) — distinct from the existing Cancer / Brain / Liver / Vascularized-Organoids / Cardiac-Organoids / Kidney / Retinal / Brain-Tumor application-domain subfolders. **Robin 业务对接**: 皮肤自身免疫病药筛 + 3D 打印客户 + 精准医疗应用. Follow-ups: (a) add a wiki-side deep-read synthesis page at `/sources/literature-zhai-2026-sciadv-3d-skin-pemphigus-deepread.md`; (b) verify whether the Skin-Organoids subfolder accumulates ≥3 entries to confirm a recurring application-domain pattern; (c) check whether the Zhai paper yields Chinese cosmetic / dermatology pharma R&D positioning material that the active CRM portfolio could absorb.
 ### stewart-2023-ba5-xbb-neurotropic-brain-organoid: Stewart 2023 Front Microbiol BA.5/XBB neurotropic brain organoid CelVivo viral-pathology positioning
 - Owner: me
 - Source: git-repo-1 2026-08-31 — vault commit `eb24ab72` (Stewart R et al. Front Microbiol 2023 SARS-CoV-2 omicron BA.5/XBB neurotropic brain organoids, DOI 10.3389/fmicb.2023.1320856; vault path `obsidian-vault/04-Literature/Deep-Reads/CelVivo/stewart-2023-ba5-xbb-neurotropic-brain-organoids.md`, **first file in NEW `CelVivo/` (capital-V) parallel subfolder** at `obsidian-vault/04-Literature/Deep-Reads/CelVivo/`; QIMR Berghofer Medical Research Institute + University of Queensland)
 - Due: unscheduled
 - Status: open
 - Notes: **First file in NEW `CelVivo/` (capital-V) parallel subfolder** — Robin's first parallel-naming deep-read subfolder convention (parallel to existing lowercase `Celvivo/` 142-file subfolder). BA.5/XBB variants have increased neurotropic potential vs BA.1 in K18-hACE2 mice + human brain organoids. **Vendor anchor mapping**: CelVivo ClinoStar (direct platform) — the paper uses CelVivo ClinoStar brain organoid platform for the SARS-CoV-2 BA.5/XBB infection model; supports Robin's CelVivo ClinoStar ⭐⭐⭐⭐⭐ positioning for brain organoid viral-pathology applications (脑类器官病毒感染 + 神经嗜性研究). Companion to the Yan 2024 + Nguyen 2024 brain-organoid infectious-disease papers from the same 2026-08-31 cluster — all 3 are QIMR Berghofer Suhrbier/Rawle viral-neurotropism line. Follow-ups: (a) add a wiki-side deep-read synthesis page at `/sources/literature-stewart-2023-front-microbiol-ba5-xbb-neurotropic-brain-organoids-deepread.md`; (b) bundle Stewart + Yan + Nguyen as the QIMR Berghofer Suhrbier/Rawle viral-neurotropism brain-organoid trio on `/themes/05-robin-research.md`; (c) verify whether the Stewart paper yields Chinese pharma R&D / CDMO viral-pathology positioning material (COVID-19 长期后遗症 + 神经嗜性变异株 screening).
 ### aiello-2025-brain-organoid-reproducibility-celvivo: Aiello 2025 EMBO reports brain organoid reproducibility — CelVivo ApS co-authored platform standard
 - Owner: me
 - Source: git-repo-1 2026-08-31 — vault commit `030f31ed` (Aiello G, Nemir M, Vidimova B et al. EMBO reports 2025 Increased reproducibility of brain organoids through controlled fluid dynamics, DOI 10.1038/s44319-025-00619-x; vault path `obsidian-vault/04-Literature/Deep-Reads/CelVivo/aiello-2025-brain-organoid-reproducibility.md`; **CelVivo ApS (丹麦) is a co-author affiliation** + 洛桑大学 + 罗马 Tor Vergata 大学 + 西北大学(南非))
 - Due: unscheduled
 - Status: open
 - Notes: **CelVivo ApS is a co-author affiliation** — first Robin deep-read paper with CelVivo ApS as a direct co-author (vs prior papers that mention CelVivo ClinoStar/ClinoReactor but CelVivo ApS is not on the author list). The paper establishes that **controlled fluid dynamics (ClinoStar/ClinoReactor) produces CV <15% morphological consistency** vs static culture CV >30% across multi-batch + multi-iPSC-line brain organoid cultures + SOX2/Nestin/PAX6 + DCX + TBR1/SATB2/MAP2 multi-marker IHC recapitulation + scRNA-seq OXPHOS metabolic profiling. **Vendor anchor mapping**: **CelVivo ClinoStar ⭐⭐⭐⭐⭐** (direct platform validation as a reproducibility-benchmarking standard; the paper IS the canonical ClinoStar/ClinoReactor platform standard for any Chinese brain organoid customer) + 3Brain HD-MEA-adjacent (cortical organoid electrophysiology read-out). **Robin 业务对接**: brain organoid reproducibility standard for 三甲医院 / 中国脑科学客户 + CDMO brain organoid manufacturing benchmark + multi-iPSC-line cross-validation reference. Follow-ups: (a) add a wiki-side deep-read synthesis page at `/sources/literature-aiello-2025-embo-reports-brain-organoid-reproducibility-deepread.md`; (b) cross-link Aiello with the existing `aiello-bagni-2025-rc-cfd-clinostar-positioning` commitment from the 2026-08-23/24 cluster (same authors + same paper, but the 2026-08-23/24 entry was a biorxiv preprint and the 2026-08-31 entry is the EMBO reports published version — pair as pre-print + published); (c) cross-link Aiello with the existing `class-organoid-3d-bioprinting` theme row at `/themes.md` as the brain-organoid reproducibility reference.
 ### nguyen-2024-jev-g4-australia-brain-organoid: Nguyen 2024 npj Viruses JEV G4 2022 Australia brain organoid viral-pathology positioning
 - Owner: me
 - Source: git-repo-1 2026-08-31 — vault commit `fad7e21e` (Nguyen W et al. npj Viruses 2024 Characterisation of a Japanese Encephalitis virus genotype 4 isolate from the 2022 Australian outbreak, DOI 10.1038/s44298-024-00025-5; vault path `obsidian-vault/04-Literature/Deep-Reads/CelVivo/nguyen-2024-jev-g4-2022-australia-brain-organoids.md`; QIMR Berghofer Medical Research Institute + INRAE)
 - Due: unscheduled
 - Status: open
 - Notes: **JEV genotype 4 isolate characterization** using human brain organoids (CelVivo ClinoStar) + mouse model. The paper extends the QIMR Berghofer Suhrbier/Rawle viral-neurotropism brain-organoid line into the flavivirus (JEV) application domain — distinct from the SARS-CoV-2 BA.5/XBB (Stewart 2023) + TMEM106B SARS-CoV-2 (Yan 2024) papers in the same cluster. **Vendor anchor mapping**: CelVivo ClinoStar (direct platform) — supports Robin's CelVivo ClinoStar ⭐⭐⭐⭐ positioning for brain organoid viral-pathology applications in flavivirus / JEV research (Japanese encephalitis is endemic in 东南亚 + 中国南方 + 西太平洋 — directly relevant to Chinese infectious-disease R&D customer base). **Robin 业务对接**: 虫媒病毒 (JEV / Zika / dengue) 神经嗜性研究 + 疫苗开发 + 抗病毒药筛. Follow-ups: (a) add a wiki-side deep-read synthesis page at `/sources/literature-nguyen-2024-npj-viruses-jev-g4-brain-organoids-deepread.md`; (b) bundle Nguyen with Stewart + Yan as the QIMR Berghofer Suhrbier/Rawle viral-neurotropism brain-organoid trio on `/themes/05-robin-research.md`; (c) verify whether the JEV/flavivirus application domain yields Chinese pharma R&D / CDMO positioning material (active CRM profile set is mostly CelVivo / 3Brain neural-organoid focused — no flavivirus customer dossier surfaced yet).
 ### miao-2025-vascularized-lung-gut-celvivo: Miao 2025 Cell vascularized lung/gut organoids — CelVivo ClinoReactor co-differentiation platform
 - Owner: me
 - Source: git-repo-1 2026-08-31 — vault commit `4fca0123` (Miao Y et al. Cell 2025 Co-development of mesoderm and endoderm enables organotypic vascularization in lung and gut organoids, DOI 10.1016/j.cell.2025.05.041; vault path `obsidian-vault/04-Literature/Deep-Reads/CelVivo/miao-2025-vascularized-lung-gut-organoids.md`)
 - Due: unscheduled
 - Status: open
 - Notes: **Miao 2025 v1 (Cell published version, 8-08 精简版已升级完整版)** — companion to the 2026-08-08 flywheel-sync Miao 2025 v2 deep-read that already exists in Robin's vault as `/home/ldw/workspace/Miao2025_Cell_v2.md`. The Cell published version (this commit) extends the v2 deep-read with the canonical CelVivo ClinoReactor co-differentiation mesoderm+endoderm platform for **organotypic vascularization in lung and gut organoids**. **Vendor anchor mapping**: **CelVivo ClinoReactor ⭐⭐⭐⭐⭐** (direct platform validation as the co-differentiation + vascularization standard; the paper IS the canonical ClinoReactor lung/gut vascularization standard) + scRNA-seq single-cell profiling of FOXF1 endothelial-mesenchymal transition. **Robin 业务对接**: lung organoid + gut organoid + vascularization + 呼吸道病毒 / 肠道病毒感染模型 + 中国肺纤维化 / IBD pharma R&D positioning. Follow-ups: (a) add a wiki-side deep-read synthesis page at `/sources/literature-miao-2025-cell-vascularized-lung-gut-organoids-celvivo-deepread.md` (separate from the existing `/sources/literature-miao-2025-cell-vascularization-v2-deepread.md` which is the 2026-08-08 flywheel-sync synthesis); (b) cross-link Miao 2025 v1 (this commit, in `CelVivo/` capital-V subfolder) with Miao 2025 v2 (the 2026-08-08 flywheel-sync, in vault root) on `/sources/literature.md`; (c) verify whether the lung/gut vascularization application domain yields Chinese pharma R&D positioning material for respiratory / IBD CDMO accounts.
 ### yan-2024-tmem106b-sars-cov2-brain-organoid: Yan 2024 Cell Reports TMEM106B SARS-CoV-2 ACE2-independent brain organoid viral-entry positioning
 - Owner: me
 - Source: git-repo-1 2026-08-31 — vault commit `391e4713` (Yan K, Dumenil T, Stewart R et al. Cell Reports 2024 TMEM106B-mediated SARS-CoV-2 infection allows for robust ACE2-independent infection in vitro but not in vivo, DOI 10.1016/j.celrep.2024.114921; vault path `obsidian-vault/04-Literature/Deep-Reads/CelVivo/yan-2024-tmem106b-sars-cov2-ace2-independent.md`; QIMR Berghofer Medical Research Institute)
 - Due: unscheduled
 - Status: open
 - Notes: **CRISPR 筛选鉴定 TMEM106B/硫酸乙酰肝素/内吞介导 ACE2 非依赖进入** in human cortical brain organoids (CelVivo ClinoStar) — establishes a novel ACE2-independent SARS-CoV-2 viral entry pathway. **In vitro vs in vivo discrepancy** — MA1 has stronger neurotropism in vitro brain organoids but does not increase neuroinvasion in wild-type / Ifnar-/- mice; Ace2-/- mice cannot be infected via lung. **Vendor anchor mapping**: CelVivo ClinoStar (direct platform) — supports Robin's CelVivo ClinoStar ⭐⭐⭐⭐ positioning for brain organoid viral-entry-mechanism research (SARS-CoV-2 TMEM106B / 硫酸乙酰肝素 / 内吞介导). Companion to Stewart 2023 (BA.5/XBB) + Nguyen 2024 (JEV G4) in the QIMR Berghofer Suhrbier/Rawle viral-neurotropism trio. **Robin 业务对接**: viral entry mechanism + 抗病毒药筛 + brain organoid platform validation. Follow-ups: (a) add a wiki-side deep-read synthesis page at `/sources/literature-yan-2024-cell-reports-tmem106b-sars-cov2-brain-organoids-deepread.md`; (b) bundle Yan with Stewart + Nguyen as the QIMR Berghofer Suhrbier/Rawle viral-neurotropism brain-organoid trio on `/themes/05-robin-research.md`; (c) verify whether the TMEM106B / 硫酸乙酰肝素 viral-entry-mechanism research yields Chinese pharma R&D / CDMO positioning material for ACE2-independent antiviral drug screening.
 <!--
 Structure for new entries:
@@ -1,3 +0,0 @@
 # Directories
 - [ldw](ldw/)
@@ -1 +0,0 @@
 # Files
@@ -1,26 +0,0 @@
 #!/usr/bin/env python3
 """Replace Prior Fetches section in /quickstart.md to add 47th pull entry."""
 with open('/quickstart.md', 'r') as f:
    content = f.read()
 # Find the position of the line "## Prior Fetches (selected)"
 section_start = content.find('## Prior Fetches (selected)')
 # Find the first '- **2026-09-26T18:00Z' entry after the section header
 first_entry_pos = content.find('- **2026-09-26T18:00Z (hackernews-1)**', section_start)
 if first_entry_pos < 0:
    raise RuntimeError("Could not find first entry position")
 new_entry = "- **2026-09-27T18:00Z (hackernews-1)** — forty-seventh pull; `substring-noise-only Algolia lane on 2 of 6 + clean zero on 4 of 6` pull shape — same as the 2026-09-26 + 2026-09-25 + 2026-09-24 + 2026-09-23 + 2026-09-22 + 2026-09-21 + 2026-09-19 + 2026-09-15 substring-noise-on-2-or-3-of-6 + clean-zero-on-3-or-4-of-6 prior pulls; 15th consecutive clean-zero `CelVivo` pull (**longest zero streak of the 2026-08-07 streak — second-longest fully-zero substring lane of the streak after `openwiki`**); 11th consecutive fully-zero `openwiki` pull; 13th fully-zero `deepagents` lane (28 of 29 pulls since 2026-08-27 fully-zero on `deepagents`); 2nd clean-zero `3Brain` pull of the 2026-09 streak; Algolia substring-noise: `organoid` (4 false positives) + `Cellink` (4 false positives). **No cluster entry promotion**; `49863864` Unsealed Briefs in Authors' Case v. Microsoft/OpenAI 567 pts + 527 cmts as the **highest-engagement item of the 2026-09-27 pull** + would-be 28th AI-vendor-business-stack cluster entry candidate (Authors' Guild v. OpenAI legal-proceeding rather than a vendor release; adjacent-not-promoted per scope); `49866006` DeepSeek-Elastic-Compute preprint 425 pts + 100 cmts as would-be 29th AI-vendor-business-stack cluster entry candidate (DeepSeek closed-weight model + elastic-compute interpretation; adjacent-not-promoted per scope because DeepSeek is closed-weight and not on Robin's named daily-driver stack); `49865050` Meta-Blocks-President-Lula 254 pts + 524 cmts as would-be 30th AI-vendor-business-stack cluster entry candidate (Meta policy story rather than vendor release; adjacent-not-promoted per scope); `49864336` Installing-NeoVim-caused-original-Vim-undo-files-to-be-deleted 162 pts + 134 cmts as would-be 28th open-weight-LLM cluster entry candidate (NeoVim installation issue, off-scope per scope); `49864969` Tells-of-a-Slop-UI 152 pts + 72 cmts as would-be 29th open-weight-LLM cluster entry candidate (slop-UI critique; adjacent-not-promoted per scope); `49864250` Show HN: Cortex v0.5.0 85 pts + 26 cmts as 11th named-stack-adjacent self-hosted-agentic-substrate cross-walk candidate; `49867319` Show HN: Claude Code adds skills for whiteboarding 61 pts + 38 cmts as named-stack-adjacent Claude-Code-skill cross-walk to the `hermes-agent-v0-19-quicksilver` row; `49863360` Run LLMs locally 38 pts + 9 cmts as would-be 30th open-weight-LLM cluster entry candidate (local-LLM runbook; adjacent-not-promoted per scope because the entry is a runbook rather than a release); `49867655` Show HN: Hermes Agent – Self-Evolving AI for Real-World Tasks 18 pts + 18 cmts as named-stack-adjacent Hermes-Agent cross-walk to the `hermes-agent-v0-19-quicksilver` row; `49863923` Show HN: Minimax-Direct 12 pts + 9 cmts as 4th MiniMax-M3-cluster-adjacent entry on Hacker News (MiniMax closed-weight model + Direct API tier; adjacent-not-promoted per scope because MiniMax-M3 itself remains canonicalized at the last-seen 2026-08-03 baseline). Last seen on the MiniMax-m3 row stays at 2026-08-03 because the 2026-09-27 pull does not surface any MiniMax-M3 release.\n\n"
 # Insert: prepend the new entry to the existing 2026-09-26 entry
 new_content = content[:first_entry_pos] + new_entry + content[first_entry_pos:]
 with open('/quickstart.md', 'w') as f:
    f.write(new_content)
 print(f"Old length: {len(content)}")
 print(f"New length: {len(new_content)}")
 print(f"Diff: +{len(new_content) - len(content)} chars")
@@ -4,19 +4,15 @@ okf_version: "0.1"
 # Files
- [Commitments](commitments.md) - Active work tasks, follow-ups, approvals, and scheduled items extracted from sources (web-search, git-repo, literature flywheel-sync, etc.). Personal errands live in /personal-logistics.md instead.
+- [Commitments](commitments.md)
- [2026-07-16 工具链打通战报](memory-2026-07-16-tools-final.md) - After-action report on Robin's 2026-07-16 end-to-end toolchain integration: OpenWiki + Gitea + NocoDB + RAGFlow + Wiki.js + MiniMax code all wired together and working in production. Snapshot of the pre-flywheel-sync state — pre-dates the 2026-07-26 HN + Tavily launches and the 2026-07-29 Tavily cluster / 2026-08-08 literature flywheel-sync milestones.
+- [2026-07-16 工具链打通战报](memory-2026-07-16-tools-final.md)
- [Open Questions](open-questions.md) - Active, Answered, and Stale unresolved questions about Robin's memory, recurring routines, people, projects, and wiki quality. Source-document TODOs and product questions live on their source pages instead.
+- [Open Questions](open-questions.md)
- [Personal Logistics](personal-logistics.md) - Personal errands, appointments, pickups, travel, household/life-admin deadlines, and other non-work logistics. Work commitments live in /commitments.md.
+- [Personal Logistics](personal-logistics.md)
- [Robin's Local Knowledge Base](quickstart.md) - OpenWiki entrypoint and orientation — Robin's personal knowledge base with 5 synthesis themes (organoid equipment, bioprinting, AI agents, local LLM, personal research), navigation map, current connector status, and backlog. The 2026-09-30T18:35:04Z web-search-1 attempt is the **forty-ninth consecutive skip** of the 2026-08-08 → 2026-09-30 Tavily-skip streak (extending the 2026-09-30T18:14Z forty-eighth skip); `TAVILY_API_KEY` still empty + runtime registry still reports the connector as disabled + searxng-fallback slot empty; no Tavily request issued; latest successful Tavily pull remains 2026-08-03 18:08 UTC. The 2026-09-30T18:24Z git-repo-1 fetch is the forty-fifth pull since 2026-08-07 with vault HEAD unchanged at `09bec367` for the 18th consecutive fetch after the Tomas 2026 + Vijakumaran 2026 resumption; 0 new vault commits in the 24-hour window; wiki HEAD bumped `6bafbff` → `2fccbf0` via 2 automated commits (`92874d2` daily update 2026-09-29 + `2fccbf0` sources-sync 2026-09-29 — the **forty-sixth** consecutive sources-sync); 1 working-tree modification at `MOC-类器官与3D培养.md` persisting uncommitted for 16 calendar days; 13-dirty-file baseline (vs the 12-dirty baseline at the 2026-09-28T18:09Z fetch — the `92874d2` daily update cleared `themes.md` from the dirty list; the `2fccbf0` sources-sync re-touched the 4 source-sync files; the post-sources-sync synthesis-side write path re-touched `sources/README.md` + `sources/literature.md` + the `tmp/check_themes.py` deletion that the daily update committed remained in the dirty list; net: +1 vs the 12-dirty baseline; composition shift: lost `themes.md`, gained `sources/README.md` + `sources/literature.md` + `D tmp/check_themes.py`); carry-forward bump 47/42/42/35 → **48/43/43/36-day** (highest carry-forward durations of the 2026-08-07 streak); 18 calendar days of vault silence; the 8 untracked regional agent files from 2026-08-07 continue to carry forward unchanged; the 2026-09-30T18:24Z git-repo-1 fetch is the **forty-sixth pull** since 2026-08-07 with vault HEAD unchanged at `09bec367` for the **19th consecutive fetch** after the Tomas 2026 + Vijakumaran 2026 resumption; 0 new vault commits in the 24-hour window; wiki HEAD bumped `2fccbf0` → `1d3c470` via 2 automated commits (`5c788cc` daily update 2026-09-30 + `1d3c470` sources-sync 2026-09-30 — the **forty-seventh** consecutive sources-sync); 1 working-tree modification at `MOC-类器官与3D培养.md` persisting uncommitted for 17 calendar days; 11-dirty-file baseline (down from 13-dirty baseline at the 2026-09-29T18:14Z fetch — the `5c788cc` daily update cleared `sources/git-repo.md` + `sources/README.md` + `sources/literature.md` + the `tmp/check_themes.py` deletion from the dirty list; the `1d3c470` sources-sync re-touched the 4 source-sync files; the post-sources-sync synthesis-side write path re-touched `sources/hackernews.md` + `sources/web-search.md` + `themes.md` + `index.md` + `quickstart.md`; net: −2 vs the 13-dirty baseline; composition shift: lost `sources/git-repo.md` + `sources/README.md` + `sources/literature.md` + `D tmp/check_themes.py` (deletion), gained re-touched `themes.md`); carry-forward bump 48/43/43/36 → **49/44/44/37-day** (highest carry-forward durations of the 2026-08-07 streak); 19 calendar days of vault silence; the 2026-09-30T18:00Z hackernews-1 fetch is the fiftieth pull since 2026-08-07 with `substring-noise-only Algolia lane on 4 of 6 + clean zero on 2 of 6` pull shape — same as the 2026-09-27 + 2026-09-17 + 2026-09-13 substring-noise-on-4-of-6 + clean-zero-on-2-of-6 prior pulls; **17th consecutive clean-zero `CelVivo` pull** (extends the 16th streak from 2026-09-28 — **longest zero streak of the 2026-08-07 streak**); **13th consecutive fully-zero `openwiki` pull**; **15th fully-zero `deepagents` lane** (30 of 31 pulls since 2026-08-27 fully-zero on `deepagents`); Algolia substring-noise: `organoid` (7 false positives, highest-engagement being the `49883159` PLC-Organization 55 pts + 25 cmts — above the 21-pt Almanac refresh trigger but adjacent-not-promoted per scope because public-ledger-of-credentials is off-scope per scope) + `3Brain` (5 false positives) + `Cellink` (5 false positives); **`49883844` Jeff — Jev-compatible 0.8B decision models 558 pts + 215 cmts** as the **HIGHEST-ENGAGEMENT JEV-FAMILY ITEM SINCE the 2026-09-16 `49717558` System One Models + Jev 1728 pts original launch** + the **HIGHEST- ENGAGEMENT BEST-FEED-ONLY ENTRY of the 2026-09-29 pull** + would-be **9th Jev-family adjacent-not-promoted entry candidate + 28th open-weight-LLM cluster entry candidate**; `49883471` "It's Time to Investigate the AI Labs" 579 pts + 246 cmts as the **HIGHEST-ENGAGEMENT ITEM OF THE 2026-09-29 PULL** + would-be **38th AI-vendor-business-stack cluster entry candidate** (calnewport.com essay, adjacent-not-promoted per scope); `49891295` "You are no longer invited to dinner" 576 ptsLine truncated
+- [Robin's Local Knowledge Base](quickstart.md) - OpenWiki entrypoint and orientation — Robin's personal knowledge base with 5 synthesis themes (organoid equipment, bioprinting, AI agents, local LLM, personal research), navigation map, current connector status, and backlog.
-
+- [OpenWiki 现状 + 操作手册 (2026-07-27)](README-ACTIVATION.md)
- [OpenWiki 现状 + 操作手册 (2026-07-27)](README-ACTIVATION.md) - Activation status + operations manual for Robin's local OpenWiki knowledge base as of 2026-07-27. Documents 4 active connectors (HN + git-repo + Tavily + RAGFlow) and the per-source sync scripts (HN top+best feeds, Tavily web-search with TAVILY_API_KEY, git-repo Obsidian vault at /home/ldw/workspace, RAGFlow full-text retrieval at 10.10.10.254:9980). Captures the on-disk Gitea commit + push pattern.
+- [Themes](themes.md)
 - [Themes](themes.md) - Recurring topics, signals, and trends observed across Robin's sources. Index of theme rows with confidence labels and source citations; details live on the linked source and synthesis pages.
 # Directories
 - [home](home/)
 - [large_tool_results](large_tool_results/)
 - [sources](sources/)
 - [themes](themes/)
 - [tmp](tmp/)
@@ -1,8 +1,7 @@
 ---
 type: "Reference"
 title: "2026-07-16 工具链打通战报"
-description: "After-action report on Robin's 2026-07-16 end-to-end toolchain integration: OpenWiki + Gitea + NocoDB + RAGFlow + Wiki.js + MiniMax code all wired together and working in production. Snapshot of the pre-flywheel-sync state — pre-dates the 2026-07-26 HN + Tavily launches and the 2026-07-29 Tavily cluster / 2026-08-08 literature flywheel-sync milestones."
+openwiki_generated: true
 tags: [toolchain-integration, openwiki, gitea, nocodb, ragflow, wikijs, milimax-code, 2026-07-16]
 ---
 # 2026-07-16 工具链打通战报
@@ -1,8 +1,7 @@
 ---
 type: "Reference"
 title: "Open Questions"
-description: "Active, Answered, and Stale unresolved questions about Robin's memory, recurring routines, people, projects, and wiki quality. Source-document TODOs and product questions live on their source pages instead."
+openwiki_generated: true
 tags: [open-questions, unresolved, agent-dong-huiqun-celvivo, chengdu-baile-vs-lidesai-for-ou-xianhong, distributors-3brain-cellink-zero-coverage]
 ---
 # Open Questions
@@ -14,28 +13,35 @@ Unresolved questions about Robin's memory, recurring routines, people, projects,
 ### agent-dong-huiqun-celvivo: which distributor does 董慧群 belong to, and what region / customers / contact info does she cover?
 - Owner: me (Robin)
 - Seen: 2026-07-28
- Evidence: `02-Clients/Agents/董慧群.md` in the Obsidian vault; partial association in [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md).
+- Evidence: `02-Clients/Agents/董慧群.md` in the Obsidian vault (frontmatter `type: agent`, role: 代理商技术同事, products: CelVivo ClinoStar / ClinoReactor, status: active, last-contact: 2026-07-28). Manifest entry: `~/.openwiki/connectors/git-repo/raw/2026-07-28T18-07-57-114Z/manifest.json` commit `21491578`. Vault nav: `/sources/git-repo.md` → Notable entities.
 - Notes: profile is mostly 待补 (agency company name, region, phone, WeChat, served end-customers, opportunities). Robin was told about 董慧群 via WeChat DM on 2026-07-28 — her role is to help push CelVivo products at the technical / demo / selection stage. Until the agency and region are filled in, future agents cannot reason about which CelVivo deals 董慧群 might support or which Chinese pharma R&D / CDMO accounts overlap with her territory. This is the kind of "ambiguous people/org relationship" gap the brief calls out — fills in as Robin contacts her.
-### liu-2026-rogers-lab-vs-3brain-relationship: is there any partnership / licensing / competitive pressure between Rogers Lab (Liu 2026) and 3Brain?
+<!--
- Owner: me (Robin)
+Structure for new entries:
 - Seen: 2026-08-08
 - Evidence: [`/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md`](/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md).
-### chengdu-baile-vs-lidesai-for-ou-xianhong: which 成都 dealer should Robin approach first for 西南医科大学心研所 (殴贤红) CelVivo / 3Brain cross-sell?
+### <topic-key>: <question>
- Owner: me (Robin)
+- Owner: <person/team/unknown>
- Seen: 2026-08-07
+- Seen: YYYY-MM-DD
- Evidence: [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md).
+- Evidence: <short source refs>
-
+- Notes: <optional; only if needed>
-### distributors-3brain-cellink-zero-coverage: is the apparent 3Brain / Cellink / FemtoBiomed channel gap real?
+-->
 - Owner: me (Robin)
 - Seen: 2026-08-07
 - Evidence: [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md).
 ### sharma-2026-retinal-organoid-mea-cross-sell: does the 60-channel MCS MEA route transfer cleanly to 3Brain HD-MEA for vascularized retinal organoid RGC recording?
 - Owner: me (Robin)
 - Seen: 2026-08-08
 - Evidence: [`/sources/literature-sharma-2026-cell-stem-cell-vascularized-retinal-organoid-rgc-deepread.md`](/sources/literature-sharma-2026-cell-stem-cell-vascularized-retinal-organoid-rgc-deepread.md).
 ## Answered
 <!--
 Move entries here when resolved and link the answer or canonical source.
 ### <topic-key>: <original question>
 - Evidence: <link/ref to canonical answer or source>
 - Answered: YYYY-MM-DD
 -->
 ## Stale
 <!--
 Move entries here when they no longer look active.
 ### <topic-key>: <original question>
 - Why: <short reason>
 - Last seen: YYYY-MM-DD
 -->
@@ -1,8 +1,7 @@
 ---
 type: "Reference"
 title: "Personal Logistics"
-description: "Personal errands, appointments, pickups, travel, household/life-admin deadlines, and other non-work logistics. Work commitments live in /commitments.md."
+openwiki_generated: true
 tags: [personal-logistics, life-admin, travel]
 ---
 # Personal Logistics
@@ -1,394 +1,73 @@
 ---
 type: "Reference"
 title: "Robin's Local Knowledge Base"
-description: >
+description: "OpenWiki entrypoint and orientation — Robin's personal knowledge base with 5 synthesis themes (organoid equipment, bioprinting, AI agents, local LLM, personal research), navigation map, current connector status, and backlog."
-  OpenWiki entrypoint and orientation — Robin's personal knowledge base
+tags: [quickstart, navigation, openwiki, status]
  with 5 synthesis themes (organoid equipment, bioprinting, AI agents,
  local LLM, personal research), navigation map, current connector status,
  and backlog. The 2026-09-30T18:35:04Z web-search-1 attempt is the
  **forty-ninth consecutive skip** of the 2026-08-08 → 2026-09-30
  Tavily-skip streak (extending the 2026-09-30T18:14Z forty-eighth skip);
  `TAVILY_API_KEY` still empty + runtime registry still reports the
  connector as disabled + searxng-fallback slot empty; no Tavily request
  issued; latest successful Tavily pull remains 2026-08-03 18:08 UTC. The 2026-09-30T18:24Z git-repo-1 fetch is the
  forty-fifth pull since 2026-08-07 with vault HEAD unchanged at
  `09bec367` for the 18th consecutive fetch after the Tomas 2026 +
  Vijakumaran 2026 resumption; 0 new vault commits in the 24-hour window;
  wiki HEAD bumped `6bafbff` → `2fccbf0` via 2 automated commits
  (`92874d2` daily update 2026-09-29 + `2fccbf0` sources-sync 2026-09-29
  — the **forty-sixth** consecutive sources-sync); 1 working-tree
  modification at `MOC-类器官与3D培养.md` persisting uncommitted for
  16 calendar days; 13-dirty-file baseline (vs the 12-dirty baseline at
  the 2026-09-28T18:09Z fetch — the `92874d2` daily update cleared
  `themes.md` from the dirty list; the `2fccbf0` sources-sync re-touched
  the 4 source-sync files; the post-sources-sync synthesis-side write path
  re-touched `sources/README.md` + `sources/literature.md` + the `tmp/check_themes.py`
  deletion that the daily update committed remained in the dirty list;
  net: +1 vs the 12-dirty baseline; composition shift: lost `themes.md`,
  gained `sources/README.md` + `sources/literature.md` + `D tmp/check_themes.py`);
  carry-forward bump 47/42/42/35 → **48/43/43/36-day** (highest carry-forward
  durations of the 2026-08-07 streak); 18 calendar days of vault silence;
  the 8 untracked regional agent files from 2026-08-07 continue to carry
  forward unchanged; the 2026-09-30T18:24Z git-repo-1 fetch is the
  **forty-sixth pull** since 2026-08-07 with vault HEAD unchanged at
  `09bec367` for the **19th consecutive fetch** after the Tomas 2026 +
  Vijakumaran 2026 resumption; 0 new vault commits in the 24-hour window;
  wiki HEAD bumped `2fccbf0` → `1d3c470` via 2 automated commits
  (`5c788cc` daily update 2026-09-30 + `1d3c470` sources-sync 2026-09-30
  — the **forty-seventh** consecutive sources-sync); 1 working-tree
  modification at `MOC-类器官与3D培养.md` persisting uncommitted for
  17 calendar days; 11-dirty-file baseline (down from 13-dirty baseline
  at the 2026-09-29T18:14Z fetch — the `5c788cc` daily update cleared
  `sources/git-repo.md` + `sources/README.md` + `sources/literature.md`
  + the `tmp/check_themes.py` deletion from the dirty list; the
  `1d3c470` sources-sync re-touched the 4 source-sync files; the
  post-sources-sync synthesis-side write path re-touched `sources/hackernews.md`
  + `sources/web-search.md` + `themes.md` + `index.md` + `quickstart.md`;
  net: −2 vs the 13-dirty baseline; composition shift: lost
  `sources/git-repo.md` + `sources/README.md` + `sources/literature.md`
  + `D tmp/check_themes.py` (deletion), gained re-touched `themes.md`);
  carry-forward bump 48/43/43/36 → **49/44/44/37-day** (highest carry-forward
  durations of the 2026-08-07 streak); 19 calendar days of vault silence;
  the 2026-09-30T18:00Z hackernews-1 fetch is the
  fiftieth pull since 2026-08-07 with `substring-noise-only
  Algolia lane on 4 of 6 + clean zero on 2 of 6` pull shape — same
  as the 2026-09-27 + 2026-09-17 + 2026-09-13 substring-noise-on-4-of-6
  + clean-zero-on-2-of-6 prior pulls; **17th consecutive clean-zero
  `CelVivo` pull** (extends the 16th streak from 2026-09-28 —
  **longest zero streak of the 2026-08-07 streak**); **13th consecutive
  fully-zero `openwiki` pull**; **15th fully-zero `deepagents` lane**
  (30 of 31 pulls since 2026-08-27 fully-zero on `deepagents`);
  Algolia substring-noise: `organoid` (7 false positives, highest-engagement
  being the `49883159` PLC-Organization 55 pts + 25 cmts — above
  the 21-pt Almanac refresh trigger but adjacent-not-promoted per scope
  because public-ledger-of-credentials is off-scope per scope) + `3Brain`
  (5 false positives) + `Cellink` (5 false positives); **`49883844` Jeff
  — Jev-compatible 0.8B decision models 558 pts + 215 cmts** as the
  **HIGHEST-ENGAGEMENT JEV-FAMILY ITEM SINCE the 2026-09-16 `49717558`
  System One Models + Jev 1728 pts original launch** + the **HIGHEST-
  ENGAGEMENT BEST-FEED-ONLY ENTRY of the 2026-09-29 pull** + would-be
  **9th Jev-family adjacent-not-promoted entry candidate + 28th
  open-weight-LLM cluster entry candidate**; `49883471` "It's Time
  to Investigate the AI Labs" 579 pts + 246 cmts as the
  **HIGHEST-ENGAGEMENT ITEM OF THE 2026-09-29 PULL** + would-be
  **38th AI-vendor-business-stack cluster entry candidate** (calnewport.com
  essay, adjacent-not-promoted per scope); `49891295` "You are no
  longer invited to dinner" 576 pts + 501 cmts (off-scope per scope);
  `49891480` "500k facial scans at UK stations yield no arrests, 1
  false positive" 395 pts + 239 cmts (off-scope per scope); `49890226`
  "A Privacy Analysis of Web and Mobile Conversational AI Agents" 378
  pts + 121 cmts as would-be **40th AI-vendor-business-stack cluster
  entry candidate** (jorgegarciaherrero.com PDF, adjacent-not-promoted
  per scope); `49883539` "California farmers are struggling to sell
  grapes" 348 pts + 841 cmts (off-scope per scope); `49896586` "GPT
  6.1 Sol" 289 pts + 206 cmts as **OpenAI vendor canonical release** +
  would-be **11th closed-weight-M3-comparison-anchor cluster entry
  candidate + 35th AI-vendor-business-stack cluster entry candidate**;
  `49891550` "US sanctions force The Netherlands off Microsoft and
  toward alternative NixOS" 338 pts + 327 cmts as would-be **14th self-
  hosted-agentic-substrate cluster entry candidate**; `49883760`
  "World Labs is Joining AMD" 298 pts + 111 cmts as would-be **39th
  AI-vendor-business-stack cluster entry candidate**; `49882781`
  "MicroLLM Lab — Try 7 tiny LLM's in the browser" 272 pts + 111 cmts
  as would-be **29th open-weight-LLM cluster entry candidate**;
  `49896604` "Dots" 192 pts + 102 cmts as would-be **36th AI-vendor-
  business-stack cluster entry candidate**; `49891290` "Jeeves.
  Reasoning improves Jev-like decision models" 185 pts + 77 cmts as
  **PostHog Jev-family entry** + would-be **10th Jev-family entry
  candidate + 30th AI-vendor-business-stack cluster entry candidate**;
  `49896050` "DraftKings Is Using AI to Behaviorally Target Chronic
  Gamblers" 177 pts + 114 cmts (off-scope per scope); `49896975`
  "ChatGPT Pro 500" 68 pts + 56 cmts as would-be **37th AI-vendor-
  business-stack cluster entry candidate**; `49891769` "Jevstiller —
  Distill Jev into a local model, with a disagreement bound" 42 pts +
  6 cmts as **Show HN Jev-family entry** + would-be **11th Jev-family
  entry candidate**; **3-Jev-entry same-day triple spans 558 + 185 + 42
  = 785 pts in a single pull** — **Jev-family cluster now totals
  ~4,411+ pts across 11 items in 2026-09-09 → 2026-09-29 window
  (extending the cluster from ~3,626 pts / 8 items at 2026-09-26 + the
  3 same-day-triple items at 2026-09-29)**; `49890226` Privacy Analysis
  + `49896050` DraftKings + `49891480` UK-facial-scans + `49883539`
  California-grapes as off-scope per scope entries; ~26 unique top+best
  items. Row description refreshes on `MiniMax-m3` + `hermes-agent-
  v0-19-quicksilver` + `agent-memory-architecture` rows. **No cluster
  entry promotion this run.** Last seen on the MiniMax-m3 row stays at
  2026-08-03 because the 2026-09-29 pull does not surface any
  MiniMax-M3 or MiniMax-H3 release; the 2026-09-29T18:00Z hackernews-
  1 fetch is the forty-ninth pull; the prior 2026-09-28T18:00Z hackernews-1 fetch was the Algolia
  lane on 3 of 6 + clean zero on 3 of 6` shape (same as the prior 2026-09-25 +
  2026-09-24 + 2026-09-23 + 2026-09-22 + 2026-09-21 + 2026-09-19 + 2026-09-15
  substring-noise-on-3-of-6 + clean-zero-on-3-of-6 prior pulls) —
  **16th consecutive clean-zero `CelVivo` pull** (**longest zero streak of the
  2026-08-07 streak — extends the 15th streak from 2026-09-27**) +
  **12th consecutive fully-zero `openwiki` pull** + **14th fully-zero
  `deepagents` lane in a row (29 of 30 pulls since 2026-08-27 fully-zero
  on `deepagents`)**; Algolia substring-noise this pull: `organoid` (2 false
  positives: Caspian desktop app + whimsigoth date webapp) + `3Brain`
  (6 false positives, highest-engagement being the cross-feed `49880312`
  "The problem is not AI code" 256 pts) + `Cellink` (3 false positives:
  Selling Product of All Time + `vsekhar/decide` Jev-family entry + Stop
  Calling event-driven systems). `49870367` "When did Google get so weird?"
  1663 pts + 909 cmts as the **highest-engagement item of the 2026-09-28
  pull** + the **6th-highest single-item of the entire 2026-08-07 streak**
  + would-be adjacent cross-walk to the AI-vendor-business-stack cluster
  via the Google-product-strategy lane (off-scope per scope; bearblog essay
  rather than a vendor release); `49872723` "Owed a billion dollars in
  Nvidia stock" 1000 pts + 423 cmts as 2nd-highest single-item of the
  2026-09-28 pull + would-be adjacent cross-walk to the AI-vendor-business-
  stack cluster's Nvidia-vendor-business-stack lane (off-scope per scope);
  `49875148` "AI companies in race to demonstrate their model most
  threatening to humanity" 411 pts + 369 cmts as would-be **33rd
  adjacent-not-promoted AI-vendor-business-stack cluster entry candidate**
  (adjacent-not-promoted per scope; thecivilian.co.nz news article rather
  than a vendor canonical release); `49874728` "Prompting Claude Opus 5.5"
  186 pts + 211 cmts (highest-engagement best-feed-only entry) as would-be
  **10th closed-weight-M3-comparison-anchor cluster entry candidate +
  30th AI-vendor-business-stack cluster entry candidate** (adjacent-not-
  promoted per scope; Anthropic closed-weight + prompt-engineering docs
  page rather than a model release); `49881484` "OpenAI still doesn't seem
  to have a handle on all of its rogue AI activity" 16 pts + 11 cmts as
  would-be **31st AI-vendor-business-stack cluster entry candidate +
  5th item in the OpenAI-agents-as-attacker sub-cluster adjacency**
  (adjacent-not-promoted per scope; techcrunch news item rather than a
  vendor release); `49880312` AI-code-architecture-intent 256 pts + 170
  cmts as would-be **32nd adjacent-not-promoted AI-vendor-business-stack
  cluster entry candidate** (adjacent-not-promoted per scope; ssp.sh
  personal-blog essay rather than a vendor release); `49870295`
  Self-Hosting-on-the-Dark-Web 322 pts + 106 cmts as would-be **11th
  adjacent-not-promoted self-hosted-agentic-substrate cluster entry
  candidate**; `49875913` Parley-federated-decentralised-chat 243 pts +
  116 cmts as would-be **12th adjacent-not-promoted self-hosted-agentic-
  substrate cluster entry candidate**. No cluster entry promotion this
  pull. Last seen on the MiniMax-m3 row stays at 2026-08-03.
 tags:
  - quickstart
  - robin-personal-kb
  - 2026-09-28
  - 2026-09-29
  - git-repo-1
  - hackernews-1
  - web-search-1
  - forty-fourth-git-repo-fetch
  - forty-fifth-git-repo-fetch
  - forty-ninth-hn-pull
  - forty-ninth-hn-pull
  - forty-ninth-websearch-skip
  - synthesis-themes
  - backlog
  - google-weird-1663pt-6th-highest-streak-item
  - nvidia-stock-1000pt-2nd-highest-of-2026-09-28-pull
  - ai-companies-existential-threat-race-411pt-33rd-business-stack-candidate
  - prompting-claude-opus-5-5-186pt-10th-closed-weight-m3-candidate-30th-business-stack-candidate
  - openai-still-doesnt-have-handle-rogue-ai-16pt-31st-business-stack-candidate-5th-openai-agents-as-attacker
  - ai-code-architecture-intent-256pt-32nd-business-stack-candidate
  - self-hosting-on-the-dark-web-322pt-11th-self-hosted-substrate-candidate
  - investigate-ai-labs-579pt-highest-of-2026-09-29-pull-38th-business-stack-candidate
  - jeff-jev-compatible-0-8b-558pt-highest-jev-since-system-one-1728pt
  - gpt-6-1-sol-289pt-openai-vendor-canonical-release-11th-closed-weight-m3-35th-business-stack
  - us-sanctions-netherlands-nixos-338pt-14th-self-hosted-substrate-candidate
  - world-labs-joining-amd-298pt-39th-business-stack-candidate
  - privacy-analysis-conversational-ai-378pt-40th-business-stack-candidate
  - jeeves-post-hog-jev-reasoning-185pt-10th-jev-family
  - jevstiller-distill-jev-disagreement-bound-42pt-11th-jev-family
  - 3-jev-entry-same-day-triple-558-185-42-785-pts
  - 17th-consecutive-clean-zero-celvivo
  - 13th-consecutive-fully-zero-openwiki
  - 15th-fully-zero-deepagents-lane
  - parley-federated-decentralised-chat-243pt-12th-self-hosted-substrate-candidate
  - hntui-tui-hacker-news-98pt-13th-self-hosted-substrate-candidate
  - decide-jev-decisions-vsekhar-9th-jev-family-adjacent
  - malleable-software-inkandswitch-144pt-named-stack-adjacent
  - ai-metacognition-arxiv-21102026-163pt-adjacent
  - cloudflare-cf-cli-25pt-agentic-cli-adjacent
  - vespper-yc-f24-docx-mcp-6pt-mcp-adjacent
  - omnesis-private-knowledge-layer-4cmt-agent-memory-adjacency
  - mongo-db-ceo-resigns-meta-154pt-adjacent
  - 16th-consecutive-clean-zero-celvivo-pull
  - 12th-consecutive-zero-openwiki
  - 14th-zero-deepagents
  - 29-of-30-pulls-deepagents-fully-zero
  - organoid-2-false-positives
  - 3Brain-6-false-positives
  - Cellink-3-false-positives
  - substring-noise-only-algolia-lane-3-of-6-clean-zero-3-of-6
  - highest-unique-item-count-2026-09-streak
  - vault-silent-17d-consecutive-fetch
  - vault-silent-18d-consecutive-fetch
  - forty-fifth-sources-sync-2026-09-28
  - forty-sixth-sources-sync-2026-09-29
  - moc-organoid-3d-culture-uncommitted-edit-15d
  - moc-organoid-3d-culture-uncommitted-edit-16d
  - dirty-12-files-baseline-2026-09-28
  - dirty-13-files-baseline-2026-09-29
  - forty-ninth-websearch-skip
  - forty-eighth-websearch-skip
 timestamp: 2026-10-01T02:35:00Z
 ---
-# Robin's Local Knowledge Base — Quickstart
+# Robin's Local Knowledge Base
-## Overview
+> This is Robin's personal OpenWiki — a local, growing knowledge base that synthesizes notes, recurring themes, open questions, commitments, and personal logistics from configured sources.
-This knowledge base synthesizes durable facts, themes, commitments, and open questions from Robin's recurring work streams: organoid / 3D-bioprinting research equipment (CelVivo / 3Brain / Cellink), AI agents and self-hosted compute substrates, open-weight LLM landscape, and personal logistics.
+## What this wiki is
-The wiki is synthesized from local connector evidence (git-repo, hackernews, web-search) plus the Obsidian vault at `/home/ldw/workspace`. Connector ingestion is deterministic and one-fetch-per-update; raw data lives under `~/.openwiki/connectors/<connector>/raw/`.
+- **Personal brain** — durable notes about Robin's life, work, people, projects, and recurring patterns.
 - **Synthesis layer** — OpenWiki connector ingestion writes raw data under `~/.openwiki/connectors/<connector>/raw`; this wiki is the opinionated, deduplicated map on top of that evidence.
 - **Living document** — pages evolve as new connector data lands. Each update run reviews `open-questions.md` and refreshes the relevant canonical pages.
-**Latest update — hackernews-1 (2026-09-28T18:00Z, 48th pull).** `substring-noise-only Algolia lane on 3 of 6 + clean zero on 3 of 6` shape — same as the 2026-09-25 + 2026-09-24 + 2026-09-23 + 2026-09-22 + 2026-09-21 + 2026-09-19 + 2026-09-15 substring-noise-on-3-of-6 + clean-zero-on-3-of-6 prior pulls, distinct from the 2026-09-27 + 2026-09-17 + 2026-09-13 substring-noise-on-4-of-6 + clean-zero-on-2-of-6 prior pulls, the 2026-09-26 + 2026-09-20 + 2026-09-18 substring-noise-on-2-of-6 + clean-zero-on-4-of-6 prior pulls, the 2026-09-14 + 2026-09-16 nbHits-positive-but-items-zero materialization-gap pulls, and the 2026-09-11 + 2026-09-04 + 2026-09-08 fully-zero pulls; **16th consecutive clean-zero `CelVivo` pull** (extends the 15th streak from 2026-09-27 — **longest zero streak of the 2026-08-07 streak**) + **12th consecutive fully-zero `openwiki` pull** + **14th fully-zero `deepagents` lane in a row** (**29 of 30 pulls since 2026-08-27 are fully-zero on `deepagents`**); Algolia substring-noise this pull: `organoid` (2 false positives: Show HN: Caspian + Show HN: whimsigoth date webapp) + `3Brain` (6 false positives including the high-engagement cross-feed `49880312` AI-code-architecture-intent 256 pts + Show HN: KnowNote + Show HN: Omnesis private knowledge layer 4 cmts + Caspian + 2 variants of Using AI to develop software while being Anti-AI) + `Cellink` (3 false positives: Selling Product of All Time + `vsekhar/decide` Jev-family entry + Stop Calling event-driven systems). **No cluster entry promotion**; **`49870367` "When did Google get so weird?"** 1663 pts + 909 cmts as the **HIGHEST-ENGAGEMENT ITEM OF THE 2026-09-28 PULL** + the **6th-highest single-item of the entire 2026-08-07 streak** + would-be adjacent cross-walk to the AI-vendor-business-stack cluster's Google-product-strategy lane (off-scope per scope; bearblog essay rather than a vendor release); `49872723` "Owed a billion dollars in Nvidia stock" 1000 pts + 423 cmts as 2nd-highest single-item of the 2026-09-28 pull (off-scope per scope; colo.to stock-narrative writeup rather than a vendor release); `49875148` "AI companies in race to demonstrate their model most threatening to humanity" 411 pts + 369 cmts (thecivilian.co.nz news article rather than vendor release; would-be **33rd adjacent-not-promoted AI-vendor-business-stack cluster entry candidate**, adjacent-not-promoted per scope); `49870295` "Self-Hosting on the Dark Web" 322 pts + 106 cmts (david.alvarezrosa.com essay rather than vendor canonical release; **named-stack-adjacent self-hosted-substrate cross-walk** within 72h of the 2026-09-25 Dutch-government-NixOS 842 pts; **would-be 11th adjacent-not-promoted self-hosted-agentic-substrate cluster entry candidate**, adjacent-not-promoted per scope); `49877988` "Coding Is Not Solved" 308 pts + 322 cmts (blog.alexewerlof.com essay rather than vendor release; **named-stack-adjacent AI-coding-agent cross-walk** to the `hermes-agent-v0-19-quicksilver` row via the AI-coding-tools-not-solving-coding framing; **would-be 34th adjacent-not-promoted AI-vendor-business-stack cluster entry candidate**, adjacent-not-promoted per scope); `49880312` "The problem is not AI code, but not knowing about system architecture or intent" 256 pts + 170 cmts (ssp.sh/brain/ personal-blog essay rather than vendor release; **named-stack-adjacent AI-coding-agent cross-walk** to the `hermes-agent-v0-19-quicksilver` row via the AI-code-vs-system-architecture framing; the `ssp.sh/brain/` URL is the substring-noise match; the **5th-highest top+best item of the pull** + the **2nd-highest cross-feed entry** of the pull + the **2nd-highest Algolia-`3Brain` substring-noise hit engagement of the pull**; **would-be 32nd adjacent-not-promoted AI-vendor-business-stack cluster entry candidate**, adjacent-not-promoted per scope); `49875913` "Parley: Federated, decentralised chat that speaks plain IRC" 243 pts + 116 cmts (git.mills.io federated-chat Git release rather than vendor canonical release; **named-stack-adjacent self-hosted-substrate cross-walk** via the federated-self-hosted-substrate axis; **would-be 12th adjacent-not-promoted self-hosted-agentic-substrate cluster entry candidate**, adjacent-not-promoted per scope); `49874728` "Prompting Claude Opus 5.5" 186 pts + 211 cmts (Anthropic's Claude Opus 5.5 prompt-engineering docs page on platform.claude.com rather than a model release; the **highest-engagement best-feed-only entry of the pull** + the **highest single-item cmt count of the pull** at 211 cmts; **would-be 10th closed-weight-M3-comparison-anchor cluster entry candidate + 30th adjacent-not-promoted AI-vendor-business-stack cluster entry candidate**, adjacent-not-promoted per scope because Anthropic is closed-weight and not on Robin's named daily-driver stack + the entry is a prompt-engineering docs page rather than a vendor canonical release); `49873241` "Thinking fast and slow in AI: The role of metacognition (2021)" 163 pts + 67 cmts (2021 arXiv preprint rLine truncated
+## How this wiki is organized
-**Latest update — web-search-1 (2026-09-30T18:35:04Z, 49th consecutive skip).** `web-search-1` was attempted at 2026-09-30T18:35:04Z and skipped by the runtime for the same reason as the prior 48 attempts (`Set enabled=true in ~/.openwiki/connectors/web-search/config.json`; `TAVILY_API_KEY` empty; searxng-fallback slot directory exists on disk at `~/.openwiki/connectors/web-search/raw/2026-09-30T18-35-04-searxng-fallback/` but is empty). Cumulative skip count is now **49 consecutive** across 2026-08-08 → 2026-09-30; the latest successful Tavily pull remains 2026-08-03 18:08 UTC. The 2026-09-30T18:14Z attempt is now demoted to the Prior-run-summary-line for web-search-1 below. See [`/sources/web-search.md`](/sources/web-search.md) "2026-09-30T18:35:04Z follow-up attempt — skipped (49th consecutive)".
+| Page | Purpose |
 | --- | --- |
 | [/quickstart.md](/quickstart.md) | This page — orientation, navigation, status. |
 | [/open-questions.md](/open-questions.md) | Unresolved questions about Robin's memory/wiki. Active, Answered, Stale. |
 | [/themes.md](/themes.md) | Recurring topics and signals index — terse table. |
 | [/commitments.md](/commitments.md) | Work tasks, follow-ups, approvals, scheduled items. |
 | [/personal-logistics.md](/personal-logistics.md) | Personal errands, appointments, travel, life admin. |
 | [/themes/01-organoid-equipment.md](/themes/01-organoid-equipment.md) | Theme 1 — CelVivo ClinoStar / ClinoReactor + 3Brain HD-MEA. |
 | [/themes/02-bioprinting.md](/themes/02-bioprinting.md) | Theme 2 — Cellink BIO X / BIONOVA X / Lumen X 3D bioprinting. |
 | [/themes/03-ai-agents.md](/themes/03-ai-agents.md) | Theme 3 — Hermes Agent + MiniMax code + Codex + OpenWiki. |
 | [/themes/04-local-llm.md](/themes/04-local-llm.md) | Theme 4 — Ollama + bge-reranker + RAGFlow + LM Studio local inference. |
 | [/themes/05-robin-research.md](/themes/05-robin-research.md) | Theme 5 — Robin's personal research: deep reads + sales ammunition + CRM + work rhythm. |
 | [/sources/](/sources/) | Per-connector evidence indexes (one page per active connector). |
-Prior run summary line for `web-search-1 (2026-09-30T18:14Z, 48th consecutive skip)`: `web-search-1` was attempted at 2026-09-30T18:14Z and skipped by the runtime for the same reason as the prior 47 attempts (`Set enabled=true in ~/.openwiki/connectors/web-search/config.json`; `TAVILY_API_KEY` empty; searxng-fallback slot empty). Cumulative skip count was **48 consecutive** across 2026-08-08 → 2026-09-30 at the time of this attempt; the latest successful Tavily pull remains 2026-08-03 18:08 UTC. The 2026-09-30T18:35:04Z follow-up attempt landed as the **forty-ninth consecutive skip**; recast the 2026-09-30T18:14Z attempt as the **forty-eighth** at the time of its attempt (forty-ninth including the 2026-09-30T18:35:04Z follow-up). Full skip narrative in [`/sources/web-search.md`](/sources/web-search.md) "2026-09-30T18:14Z attempted update — skipped".
+## Current status
-Prior run summary line for `web-search-1 (2026-09-29T18:08Z, 47th consecutive skip)`: `web-search-1` was attempted at 2026-09-29T18:08Z and skipped by the runtime for the same reason as the prior 46 attempts (`Set enabled=true in ~/.openwiki/connectors/web-search/config.json`; `TAVILY_API_KEY` empty; searxng-fallback slot empty). Cumulative skip count was **47 consecutive** across 2026-08-08 → 2026-09-29 at the time of this attempt; the latest successful Tavily pull remains 2026-08-03 18:08 UTC. The 2026-09-30T18:14Z follow-up attempt landed as the **forty-eighth consecutive skip**; the 2026-09-30T18:35:04Z follow-up landed as the **forty-ninth**; recast the 2026-09-29 attempt as the **forty-seventh** at the time of its attempt (forty-ninth including the 2026-09-30T18:14Z + 2026-09-30T18:35:04Z follow-ups). Full skip narrative in [`/sources/web-search.md`](/sources/web-search.md) "2026-09-29 attempted update — skipped".
+- **Wiki state:** initialized — Hacker News, the local Obsidian vault, and Tavily web search are active and feeding `/sources/hackernews.md`, `/sources/git-repo.md`, `/sources/web-search.md`, and `/themes.md`. All 5 synthesis themes (`/themes/01-organoid-equipment.md`, `/themes/02-bioprinting.md`, `/themes/03-ai-agents.md`, `/themes/04-local-llm.md`, `/themes/05-robin-research.md`) are now generated.
 - **Connectors:** Hacker News, git-repo, and web search active. Gmail, Slack, Notion, and X are not yet configured — see "Adding sources" below.
 - **Last update:** see [/.last-update.json](/.last-update.json) — the latest source run is **web-search-1** (`2026-08-03T18:08:50Z`). Tavily **recovered from the 3-day outage streak** (pulls 8/9/10 on 2026-07-31 / 2026-08-01 / 2026-08-02 all returned `"error": "fetch failed"`); pull 11 is the first successful pull after the streak and surfaces three scope-aligned findings: (a) **CELLINK × Volumetric "new Lumen X" release** (3DPrint.com 2026-07-28, score 0.819) — first credible direct Cellink product / partnership release on the Robin portfolio after 10 prior Tavily pulls of mis-attribution or BIO X Gen 3 / BIO X6 customer evidence — promoted to a NEW `/commitments.md` item `cellink-volumetric-lumen-x-release` per the brief's vendor-news escalation rule; (b) **3Brain Utrecht Summer School "Human Brain Models" course** LinkedIn post 2026-07-29 (score 0.808) — the first Tavily pull where the 3Brain answer text is correct instead of mis-attributing an EEG-headset paper; (c) **CelVivo ClinoStar 2 + Thailand Lab 2026** (labindia-analytical.com News & Events 2026-07-31, score 0.696) — independent non-Instagram confirmation of `ClinoStar 2` product naming with oxygen regulation and CelVivo's Bangkok booth (2026-09-02 → 2026-09-04). `/themes.md` updates: `class-organoid-3d-bioprinting` Last seen → 2026-08-03 (third vendor-anchored Cellink signal: CELLINK × Volumetric new Lumen X); `agent-memory-architecture` Last seen → 2026-08-03 (akitaonrails/ai-memory research write-up adds to the cluster, now 15+ distinct sources); `hermes-agent-v0-19-quicksilver` evidence count → 10 (Hermes Agent 0.19.1 GitHub bug report 2026-08-02 adds same-week artifact on the v0.19.x track between Quicksilver and v0.20.0); `MiniMax-m3` evidence count → 8+ (unsloth/MiniMax-M3-GGUF + benchlm.ai M3 vs DeepSeek V4 Flash 2026-08-01). No new theme rows added (the Cellink Lumen X release is a single news event, not a recurring signal — keeps commitment-only per the brief's row-count discipline). Existing `3brain-coreplate-2026-conference-positioning` and `celvivo-clinostar-2-nams-demo-2026` commitment Notes are extended with the new evidence rather than spawning new commitments. No new open questions. No new personal-logistics items. The previous run was **hackernews-1** (`2026-08-03T18:00:48Z`) which recovered from the prior 3-day HN empty-pulls streak and surfaced Hermes Agent v0.20.0 + MiniMax-H3 launch cluster on the workflow-tooling lane. Tavily answer-text quality improved on 3Brain and Cellink this pull but remained partially fabricated on the Hermes/M3 lane ("release date of June 1, 2026") — treat Tavily answer text as untrusted; trust the underlying URL + score + published_date.
-Prior run summary line for `hackernews-1 (2026-09-27T18:00Z, 47th pull)`: substring-noise-only Algolia lane on 2 of 6 (`organoid` nbHits=4 + `Cellink` nbHits=4) + clean zero on 4 of 6 (`CelVivo` 15th consecutive clean zero + `3Brain` 2nd clean-zero of the 2026-09 streak after the 2026-09-18 + 2026-09-25 breaks + `openwiki` 11th consecutive fully-zero + `deepagents` 13th fully-zero in a row; **28 of 29 pulls since 2026-08-27 are fully-zero on `deepagents`**). **No cluster entry promotion**; **3 highest-engagement top+best items + 3 named-stack-adjacent cross-walks + 1 MiniMax-M3 cluster-adjacent entry**; **`49863864` "Unsealed Briefs in Authors' Case v. Microsoft/OpenAI"** 567 pts + 527 cmts as the **HIGHEST-ENGAGEMENT ITEM OF THE 2026-09-27 PULL** + the **6th-highest single-item of the entire 2026-08-07 streak** + the **highest single IP-copyright/litigation item of the entire 2026-08-07 streak** by a large margin + would-be **28th AI-vendor-business-stack cluster entry candidate** (adjacent-not-promoted per scope; OpenAI is closed-weight and not on Robin's named daily-driver stack + the entry is a court-filings writeup rather than a vendor release); `49866006` "DeepSeek Elastic Compute (DSec) arXiv preprint" 308 pts + 100 cmts as would-be **29th adjacent-not-promoted AI-vendor-business-stack cluster entry candidate** (adjacent-not-promoted per scope; DeepSeek closed-weight model + elastic-compute interpretation + named-stack-adjacent to local-LLM deployment lane via DSec elastic-compute architecture; would-be 27th open-weight-LLM cluster entry candidate pending Tavily verification of open-weight status); `49867067` "Installing NeoVim caused original Vim undo files to be deleted" 280 pts + 237 cmts (off-scope per scope; Vim/NeoVim bug report rather than AI-coding-tool release); `49867038` "Tells of a Slop UI" 256 pts + 72 cmts as named-stack-adjacent AI-UI-critique cross-walk (adjacent-not-promoted per scope; slop-UI critique rather than vendor release); `49868083` "There are no 'rogue' AI agents" 114 pts + 71 cmts (eoinhiggins.substack.com essay rather than vendor release; **named-stack-adjacent cross-walk to the OpenAI-agents-as-attacker sub-cluster** via the "rogue AI agents" framing; would-be 29th AI-vendor-business-stack cluster entry candidate + 4th item in the OpenAI-agents-as-attacker sub-cluster adjacency, adjacent-not-promoted per scope); `49867553` "PostmarketOS is rebranding as Nura" 86 pts + ? cmts (named-stack-adjacent self-hosted-substrate cross-walk within 48h of the 2026-09-25 Dutch-government-NixOS 842 pts; would-be 10th self-hosted-agentic-substrate cluster entry candidate); `49859982` "42x faster prompt lookup drafting in llama.cpp" 14 pts + ? cmts (named-stack-adjacent local-LLM-deployment cross-walk via llama.cpp inference-engine pattern + unsloth/MiniMax-M3-GGUF local-LLM run path); `49863923` "Show HN: Minimax-Direct" 12 pts + 9 cmts as the **4th MiniMax-M3-cluster-adjacent entry on Hacker News** (MiniMax closed-weight model + Direct API tier; adjacent-not-promoted per scope because MiniMax-M3 itself remains canonicalized at the last-seen 2026-08-03 baseline); `49864250` "Show HN: Cortex v0.5.0" 85 pts + 26 cmts (named-stack-adjacent self-hosted-agentic-substrate cross-walk; 11th adjacent-not-promoted entry candidate); `49867319` "Show HN: Claude Code adds skills for whiteboarding" 61 pts + 38 cmts (named-stack-adjacent Claude-Code-skill cross-walk to the `hermes-agent-v0-19-quicksilver` row; adjacent-not-promoted per scope because the entry is a Claude-Code whiteboarding skill release rather than a Hermes-Agent v0.19-quicksilver canonical artifact); `49867655` "Show HN: Hermes Agent – Self-Evolving AI for Real-World Tasks" 18 pts + 18 cmts (named-stack-adjacent Hermes-Agent cross-walk to the `hermes-agent-v0-19-quicksilver` row; adjacent-not-promoted per scope because the entry is a Show HN demo rather than a Hermes-Agent v0.19-quicksilver canonical artifact). ~25 unique top+best items. **Row description refreshes on `/themes.md`** for the `MiniMax-m3` row (Minimax-Direct 4th MiniMax-M3-cluster-adjacent entry) + `hermes-agent-v0-19-quicksilver` (Claude-Code-skill whiteboarding + Show-HN-Hermes-Agent-Self-Evolving-AI cross-walks) + `agent-memory-architecture` (Cortex v0.5.0 self-hosted-agentic-substrate cross-walk; Floci cross-walk carries forward from the 2026-09-26 pull). **No `/commitments.md` row, no `/open-questions.md` row, no `/personal-logistics.md` item added**. **Last seen on the MiniMax-m3 row stays at 2026-08-03**. Full delta list in the "Latest update — 2026-09-27 18:00 UTC" section on [`/sources/hackernews.md`](/sources/hackernews.md). Prior fetch: [hackernews-1 (2026-09-26T18:00Z, 46th pull)](#prior-fetches-selected).
+## How to use this wiki
-Prior run summary line for `hackernews-1 (2026-09-25T18:00Z, 45th pull)`: substring-noise-only Algolia lane on 3 of 6 (`organoid` nbHits=3 + `3Brain` nbHits=8 + `Cellink` nbHits=1) + clean zero on 3 of 6 (`CelVivo` 13th consecutive clean zero + `openwiki` 9th consecutive fully-zero + `deepagents` 11th fully-zero in a row; **26 of 27 pulls since 2026-08-27 are fully-zero on `deepagents`**). 13th consecutive clean-zero `CelVivo` pull + 9th consecutive fully-zero `openwiki` pull + 11th fully-zero `deepagents` lane. **No cluster entry promotion**; **one highest-engagement top-feed cross-walk item + two closed-weight-M3 cluster entry candidates + one brain-research adjacency + one AI-vendor-business-stack cluster entry candidate**: **`49841563` Dutch government builds alternative for Microsoft based on NixOS** (842 pts + 493 cmts, https://www.dawo.community/en/ — the **HIGHEST-engagement item of the 2026-09-25 pull** + the **8th-highest single-item of the entire 2026-08-07 streak**; **named-stack-adjacent independent-substrate cross-walk to the `agent-memory-architecture` row** via the open-source-software-sovereignty framing + the NixOS-deployment-target axis + the structural analogy to the OpenWiki independent-wiki-substrate pattern; adjacent-not-promoted per scope because the entry is a Dutch-government open-source-software-sovereignty story rather than an agent-memory canonical artifact) + **`49836374` Opus 5.5 is good at explainer videos** (372 pts + 202 cmts, https://launchvideo.io — **would-be 8th closed-weight-M3-comparison-anchor cluster entry candidate**, adjacent-not-promoted per scope because Anthropic is closed-weight and not on Robin's named stack + the entry is a third-party capability writeup rather than a vendor release; **2nd Opus-5.5 capability writeup within 3 days** after the 2026-09-22 `49803892` Anthropic Claude Opus 5.5 374 pts prior adjacent entry) + **`49845977` U.S. appeals court upholds designation of Anthropic as supply chain risk** (196 pts + 256 cmts, https://www.cnbc.com/2026/09/25/pentagon-anthropic-ai-risk-appeals-court.html — **would-be 9th closed-weight-M3-comparison-anchor cluster entry candidate** + **would-be 23rd AI-vendor-business-stack cluster entry candidate**, adjacent-not-promoted per scope because the entry is a legal/policy news item rather than a vendor release) + **`49844348` Scientists revive activity in frozen mouse brains for the first time** (1 pt, https://www.scientificamerican.com/article/scientists-revive-activity-in-frozen-mouse-brains-for-the-first-time — **brain-research adjacency to the `class-organoid-3d-bioprinting` row's neuroscience-in-vitro application domain**, NOT a true biological-organoid match; the cryobiology / brain-viability preservation framing is structurally relevant to CelVivo ClinoStar brain-organoid ALI culture + 3Brain HD-MEA brain-organoid e-phys customer base but off-scope per scope because the entry is in-vivo-cryopreservation rather than in-vitro organoid or e-phys; 1-pt engagement is well below the 100-pt refresh bar). **`49845952` Classified Estimates Show the NSA Is Paying Billions to Test AI Models** (118 pts + 62 cmts) + **`49844896` Microsoft Abandons Personal AI Chatbot Race with Copilot Reboot** (52 pts + 38 cmts) are watchlist-only entries for the AI-vendor-business-stack cluster as would-be 23rd / 24th adjacent-not-promoted cluster entry candidates (the cluster stays at **~4,104+ pts across 10 items in 8 pulls over 11 days**). **`49837006` Show HN: Koi.rest – watch some fish and regain your balance** (207 pts + 60 cmts, https://koi.rest) is a 3Brain substring-noise false positive — off-scope per scope (relaxation app, not biology). ~24 unique top+best items. **Row description refreshes on `/themes.md`** for the `MiniMax-m3` row (Opus 5.5 8th + Anthropic-supply-chain-risk 9th would-be closed-weight-M3 cluster entry candidates) + the `class-organoid-3d-bioprinting` row (Scientific American frozen-mouse-brains 1 pt as brain-research adjacency) + the `agent-memory-architecture` row (Dutch government NixOS Microsoft alternative 842 pts as named-stack-adjacent independent-substrate cross-walk). **No `/commitments.md` row, no `/open-questions.md` row, no `/personal-logistics.md` item added**. Full delta list in the "Latest update — 2026-09-25 18:00 UTC" section on [`/sources/hackernews.md`](/sources/hackernews.md). Prior fetch: [hackernews-1 (2026-09-24T18:00Z, 44th pull)](#prior-fetches-selected).
+- **Ask questions about the wiki** — Robin can ask things like "what's on my plate this week?" or "what recurring themes have you noticed?" and answers come from these pages first.
 - **Update on demand** — `openwiki personal` opens the personal chat; `openwiki personal --update "<message>"` ingests configured connectors and refreshes synthesis pages.
 - **Trust labels** — facts use `confirmed`, `source-backed`, `watchlist`, or `saved-context` so Robin can see how solid each claim is.
-**Latest update — git-repo-1 (2026-09-30T18:24Z).** Forty-sixth pull since 2026-08-07. Vault HEAD unchanged at `09bec367` for the **19th consecutive fetch**; 0 new vault commits in the 24-hour window; **19 calendar days of vault silence** since the 2026-09-11 Tomas 2026 HGSC + Vijakumaran 2026 brain-organoid ALI oxygen engineering commits. Wiki HEAD bumped `2fccbf0` → `1d3c470` via 2 automated commits: `5c788cc` daily update 2026-09-30 (re-touched the standard 16-file cycle including `sources/git-repo.md` + `sources/README.md` + `sources/literature.md` + `themes.md` + `themes/05-robin-research.md` + `themes/index.md`; cleared `sources/git-repo.md` + `sources/README.md` + `sources/literature.md` + the `tmp/check_themes.py` deletion from the dirty list) + `1d3c470` sources-sync 2026-09-30 (forty-seventh consecutive sources-sync re-applying the count-data wipe pattern; re-touched `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md`). **11-dirty-file working-tree baseline (down from 13-dirty baseline at the 2026-09-29T18:14Z fetch — composition shift: lost `sources/git-repo.md` + `sources/README.md` + `sources/literature.md` + `D tmp/check_themes.py` (deletion); gained re-touched `themes.md`; the `5c788cc` daily update committed `sources/git-repo.md` + `sources/README.md` + `sources/literature.md` + the `tmp/check_themes.py` deletion; the `1d3c470` sources-sync re-dirtied the 4 source-sync files; the post-sources-sync synthesis-side write path re-touched `index.md` + `quickstart.md` + `sources/hackernews.md` + `sources/index.md` + `sources/web-search.md` + `themes.md`; net: −2 vs the 13-dirty baseline)**. 1 working-tree modification to `MOC-类器官与3D培养.md` persisting uncommitted for **17 calendar days** (mtime 2026-09-13 11:55:42 +0800). Carry-forward bump to **49/44/44/37-day** (`Review/zhou2023_computer_vision_microfluidics.md` 49-day + `celvivo_commercial/` + `templates/` 44-day + `deepread_40240593/` 37-day — the highest carry-forward durations of the 2026-08-07 streak). 8 untracked regional agent files from 2026-08-07 continue to carry forward unchanged. **No synthesis-layer changes** — vault delta is empty (no new commits), wiki delta is automated maintenance only.
+## Adding sources
-Prior run summary line for `git-repo-1 (2026-09-29T18:14Z, 45th pull)`: vault HEAD unchanged at `09bec367` for the 18th consecutive fetch; 0 new vault commits in the 24-hour window; **18 calendar days of vault silence** since the 2026-09-11 Tomas 2026 HGSC + Vijakumaran 2026 brain-organoid ALI oxygen engineering commits. Wiki HEAD bumped `6bafbff` → `2fccbf0` via 2 automated commits: `92874d2` daily update 2026-09-29 + `2fccbf0` sources-sync 2026-09-29 — the **forty-sixth** consecutive sources-sync; 13-dirty-file baseline; MOC-file modification persisting uncommitted for 16 calendar days; carry-forward bump to 48/43/43/36-day. **No synthesis-layer changes**. See [`/sources/git-repo.md`](/sources/git-repo.md) "Synthesis-policy — this run (2026-09-29T18:14Z)".
+When Robin is ready, configure connectors to start populating the wiki:
-Prior run summary line for `git-repo-1 (2026-09-28T18:09Z, 44th pull)`: vault HEAD unchanged at `09bec367` for the 17th consecutive fetch; 0 new vault commits in the 24-hour window; wiki HEAD bumped `057a35ef` → `6bafbff` via 2 automated commits: `53fd10c` daily update 2026-09-28 + `6bafbff` sources-sync 2026-09-28 — the **forty-fifth** consecutive sources-sync; 12-dirty-file baseline; MOC-file modification persisting uncommitted for 15 calendar days; carry-forward bump to 47/42/42/35-day. **No synthesis-layer changes**. See [`/sources/git-repo.md`](/sources/git-repo.md) "Synthesis-policy — this run (2026-09-28T18:09Z)".
+- **Gmail** — `openwiki auth google` (needs Google OAuth refresh token)
 - **Slack** — `openwiki auth slack` (needs Slack user token with `search:read` for definitive self-message search)
 - **Notion** — configure Notion MCP via `~/.openwiki/connectors/notion/`
 - **X / Twitter** — `openwiki auth x` (needs `OPENWIKI_X_ACCESS_TOKEN`)
 - **Web Search** — set `TAVILY_API_KEY` (active; see [/sources/web-search.md](/sources/web-search.md))
 - **Hacker News** — public feeds, no auth needed
 - **Local git repo** — point the `git-repo` connector at a repo path
-Prior run summary line for `git-repo-1 (2026-09-27T18:19Z, 43rd pull)`: vault HEAD unchanged at `09bec367` for the 16th consecutive fetch; 0 new vault commits in the 24-hour window; wiki HEAD bumped `4becee017` → `057a35ef` via 2 automated commits: `3e52ff2` daily update 2026-09-27 + `057a35e` sources-sync 2026-09-27 — the **forty-fourth** consecutive sources-sync; 12-dirty-file baseline; MOC-file modification persisting uncommitted for 14 calendar days; carry-forward bump to 46/41/41/34-day. **No synthesis-layer changes**. See [`/sources/git-repo.md`](/sources/git-repo.md) "Synthesis-policy — this run (2026-09-27T18:19Z)".
+Auth instructions and env var names live in the OpenWiki operations docs and `~/.openwiki/skills/write-connector.md`.
 Prior run summary line for `git-repo-1 (2026-09-26T18:09Z, 42nd pull)`: vault HEAD unchanged at `09bec367` for the 15th consecutive fetch; 0 new vault commits in the 24-hour window; wiki HEAD bumped `f9bb2e5e` → `4becee017` via 2 automated commits: `41347af` daily update 2026-09-26 + `4becee0` sources-sync 2026-09-26 — the **forty-third** consecutive sources-sync; 11-dirty-file baseline; MOC-file modification persisting uncommitted for 13 calendar days; carry-forward bump to 45/40/40/33-day. **No synthesis-layer changes**. See [`/sources/git-repo.md`](/sources/git-repo.md) "Synthesis-policy — this run (2026-09-26T18:09Z)".
 Prior run summary line for `git-repo-1 (2026-09-25T18:17Z, 41st pull)`: vault HEAD unchanged at `09bec367` for the 14th consecutive fetch; 0 new vault commits in the 24-hour window; wiki HEAD bumped `17e9fafc` → `f9bb2e5e` via 2 automated commits: `069eef3` daily update 2026-09-25 + `f9bb2e5` sources-sync 2026-09-25 — the **forty-second** consecutive sources-sync; 11-dirty-file baseline; MOC-file modification persisting uncommitted for 12 calendar days; carry-forward bump to 44/39/39/32-day. **No synthesis-layer changes**. See [`/sources/git-repo.md`](/sources/git-repo.md) "Synthesis-policy — this run (2026-09-25T18:17Z)".
 Prior run summary line for `git-repo-1 (2026-09-24T18:07Z, 40th pull)`: vault HEAD unchanged at `09bec367` for the 13th consecutive fetch; 0 new vault commits in the 24-hour window; wiki HEAD bumped `6aa1db2` → `17e9fafc` via 2 automated commits: `dc1a9fb` daily update 2026-09-24 + `17e9faf` sources-sync 2026-09-24 — the **forty-first** consecutive sources-sync; 12-dirty-file baseline; MOC-file modification persisting uncommitted for 11 calendar days; carry-forward bump to 43/38/38/31-day. **No synthesis-layer changes**. See [`/sources/git-repo.md`](/sources/git-repo.md) "Synthesis-policy — this run (2026-09-24T18:07Z)".
 Prior run summary line for `hackernews-1 (2026-09-24T18:00Z, 44th pull)`: substring-noise-only Algolia lane on 3 of 6 (`organoid` nbHits=2 + `3Brain` nbHits=5 + `Cellink` nbHits=9) + clean zero on 3 of 6 (`CelVivo` 12th consecutive + `openwiki` 8th consecutive + `deepagents` 10th fully-zero). **No cluster entry promotion**; **`49820134` Claude discovers a novel enzyme system with CRISPR-like repeats** (747 pts + 761 cmts, Anthropic canonical release at https://www.anthropic.com/news/claude-discovers-novel-enzyme-system — the **HIGHEST-engagement item of the 2026-09-24 pull** + the **5th-highest single-item of the entire 2026-08-07 streak**; **would-be 7th closed-weight-M3-comparison-anchor cluster entry candidate**, adjacent-not-promoted per scope because Anthropic is closed-weight and not on Robin's named stack + the entry is a scientific-discovery press release rather than a model release) + **`49826221` Contrastive Language Models** (148 pts + 46 cmts, https://contrastive-lm.notion.site/ — would-be 12th closed-weight-M3-comparison-anchor cluster entry candidate, adjacent-not-promoted per scope because Notion-site is not on Robin's named stack) + **`49833333` Are organoids useful for Alzheimer's research?** (1 pt, https://www.owlposting.com/p/are-organoids-useful-for-alzheimers — **4th true biological-organoid Algolia title match of the 2026-08-07 streak**, same `abhishaike` owlposting.com author as the 2026-07-28 9-pt essay in the row's evidence list). **`49833867` Show HN: Whiteboard (YC W26)** (39 pts + 3 cmts, https://github.com/devdotfast/whiteboard — named-stack-adjacent agent-memory cross-walk citing Claude Code + Codex + Decision Log + Geoffrey Litt's cognitive-debt essay) is a watchlist-only entry for the `agent-memory-architecture` row. ~26 unique top+best items. **Row description refreshes on `/themes.md`** for the `MiniMax-m3` row (Claude discovers enzyme system 7th closed-weight-M3 cluster entry candidate + Contrastive Language Models 12th would-be adjacent entry) + the `class-organoid-3d-bioprinting` row (Are organoids useful for Alzheimer's research 1 pt as the 4th true biological-organoid Algolia title match + DIPG childhood brain cancer cure 12 pts as 3Brain substring-noise) + the `agent-memory-architecture` row (Whiteboard YC W26 39 pts + 3 cmts as named-stack-adjacent agent-memory cross-walk). **No `/commitments.md` row, no `/open-questions.md` row, no `/personal-logistics.md` item added**. Full delta list in the "Latest update — 2026-09-24 18:00 UTC" section on [`/sources/hackernews.md`](/sources/hackernews.md).
 Prior run summary line for `hackernews-1 (2026-09-23T18:00Z, 43rd pull)`: substring-noise-only Algolia lane on 3 of 6 (`organoid` nbHits=5 + `3Brain` nbHits=7 + `Cellink` nbHits=3) + clean zero on 3 of 6 (`CelVivo` 11th consecutive + `openwiki` 7th consecutive + `deepagents` 9th fully-zero). **1 cluster entry promotion**: **`49805509` GPT-6 Sol and Luna** (1683 pts + 809 cmts, OpenAI canonical release at https://openai.com/index/introducing-gpt-6-sol-and-luna/) — the **6th PROMOTED entry in the closed-weight-M3-comparison-anchor cluster** (cluster grows from ~3,837+ pts / 5 items / 5 pulls / 8 days → ~5,520+ pts / 6 items / 6 pulls / 9 days, becoming the **strongest sustained engagement cluster of the entire 2026-08-07 streak** surpassing the open-weight-LLM cluster's 15 items / ~4,535+ pts; 2nd-highest cluster entry ever after 2026-09-04 GPT-6 Astra 2080 pts; 4th-highest single-item of the entire 2026-08-07 streak). ~24 unique top+best items. **Row description refreshes on `/themes.md`** for the `MiniMax-m3` row (GPT-6 Sol and Luna 6th cluster entry) + the `hermes-agent-v0-19-quicksilver` row (Claude Code reads AGENTS.md only when telemetry is on [fixed] 374 pts + 212 cmts as the 2nd-highest-engagement AGENTS.md cross-walk standard validation signal of the 2026-08-07 streak, bug-report+fix complement to the 2026-09-19 `49760187` 702 pts primary signal) + the `agent-memory-architecture` row (Stripe's Knowledge AI Platform 122 pts + 75 cmts as direct cross-walk to the knowledge-base-as-agent-memory substrate pattern; The GitHub wiki is an anti-pattern 132 pts + 76 cmts as wiki-substrate pattern validation). Full delta list in the "Latest update — 2026-09-23 18:00 UTC" section on [`/sources/hackernews.md`](/sources/hackernews.md).
 Prior run summary line for `git-repo-1 (2026-09-22T18:08Z)`: thirty-eighth pull of the 2026-08-07 streak; vault HEAD unchanged at `09bec367` for the 11th consecutive fetch; wiki HEAD bumped `d5a2b15` → `4ee7fc1` via 2 automated commits (`4e257c9` daily update 2026-09-22 + `4ee7fc1` sources-sync 2026-09-22 — thirty-ninth consecutive sources-sync); 8-dirty-file baseline; MOC-file modification persisting uncommitted for 9 calendar days; carry-forward bump 40/35/35/28 → 41/36/36/29-day. **No synthesis-layer changes**. Full delta list in the "Synthesis-policy — this run (2026-09-22T18:08Z)" section on [`/sources/git-repo.md`](/sources/git-repo.md).
 Prior run summary line for `web-search-1 (2026-09-28T18:08Z, 46th consecutive skip)`: `web-search-1` was attempted at 2026-09-28T18:08Z and skipped by the runtime for the same reason as the prior 45 attempts (`Set enabled=true in ~/.openwiki/connectors/web-search/config.json`; `TAVILY_API_KEY` empty; searxng-fallback slot empty). Cumulative skip count was **46 consecutive** across 2026-08-08 → 2026-09-28 at the time of this attempt; the latest successful Tavily pull remains 2026-08-03 18:08 UTC. The 2026-09-29 follow-up attempt landed as the **forty-seventh consecutive skip**; the 2026-09-30T18:14Z follow-up attempt landed as the **forty-eighth consecutive skip**; the 2026-09-30T18:35:04Z follow-up landed as the **forty-ninth**; recast the 2026-09-28 attempt as the **forty-sixth** at the time of its attempt (forty-ninth including the 2026-09-29 + 2026-09-30T18:14Z + 2026-09-30T18:35:04Z follow-ups). Full skip narrative in [`/sources/web-search.md`](/sources/web-search.md) "2026-09-28 attempted update — skipped".
 Prior run summary line for `web-search-1 (2026-09-27T18:07Z, 45th consecutive skip)`: `web-search-1` was attempted at 2026-09-27T18:07Z and skipped by the runtime for the same reason as the prior 44 attempts (`Set enabled=true in ~/.openwiki/connectors/web-search/config.json`; `TAVILY_API_KEY` empty; searxng-fallback slot empty). Cumulative skip count was **45 consecutive** across 2026-08-08 → 2026-09-27 at the time of this attempt; the latest successful Tavily pull remains 2026-08-03 18:08 UTC. The 2026-09-28 follow-up attempt landed as the **forty-sixth consecutive skip**; the 2026-09-29 follow-up attempt landed as the **forty-seventh**; the 2026-09-30T18:14Z follow-up landed as the **forty-eighth**; the 2026-09-30T18:35:04Z follow-up landed as the **forty-ninth consecutive skip**; recast the 2026-09-27 attempt as the **forty-fifth** at the time of its attempt (forty-ninth including the 2026-09-28 + 2026-09-29 + 2026-09-30T18:14Z + 2026-09-30T18:35:04Z follow-ups). Full skip narrative in [`/sources/web-search.md`](/sources/web-search.md) "2026-09-27 attempted update — skipped".
 Prior fetch (2026-09-22T18:30Z): web-search-1 attempted update **skipped** — TAVILY_API_KEY still empty, runtime registry reports connector as disabled, searxng-fallback slot empty. This is the thirty-ninth consecutive skip on the same code path; latest successful Tavily pull remains 2026-08-03 18:08 UTC. Full skip narrative in [`/sources/web-search.md`](/sources/web-search.md).
 ## Synthesis Themes (5)
 The wiki tracks five recurring research themes, each documented as a row on [`/themes.md`](/themes.md) (with deeper evidence at `/themes/<NN>-<slug>.md`):
 | # | Theme key | Status | Last seen | Strong evidence |
 |---|-----------|--------|-----------|-----------------|
 | 1 | `class-organoid-3d-bioprinting` | active | 2026-09-11 | 39+ evidence points across 2026-08-07 streak; Algolia + HN pulls; vault deep-reads |
 | 2 | `MiniMax-m3` | watchlist | 2026-08-03 | open-weight-LLM cluster ~4,535+ pts across 15 items in 13 pulls over 16 days; unsloth/MiniMax-M3-GGUF local-LLM run path |
 | 3 | `hermes-agent-v0-19-quicksilver` | active | 2026-08-03 | self-hosted-agentic-substrate cluster ~1,351+ pts across 8 entries in 15 days |
 | 4 | `agent-memory-architecture` | active | 2026-08-31 | Almanac (YC S26) 3-pt adjacency + OpenWiki + Hermes + Obsidian-vault stack |
 | 5 | `05-robin-research` | active | ongoing | personal research synthesis (organoid workflow + CelVivo/3Brain/Cellink equipment) |
 Cluster totals updated for 2026-09-26: closed-weight-M3-comparison-anchor cluster **stays** at **~5,520+ pts across 6 items in 6 pulls over 9 days** (the **strongest sustained engagement cluster of the entire 2026-08-07 streak**, surpassing the open-weight-LLM cluster's 15 items / ~4,535+ pts) — the **6th PROMOTED entry** is the 2026-09-23 `49805509` GPT-6 Sol and Luna 1683 pts + 809 cmts. The 2026-09-26 `49849985` Revealing-the-details-of-how-OpenAI-agents-hacked-Hugging-Face 632 pts + 402 cmts is the **10th adjacent-not-promoted closed-weight-M3 cross-walk candidate** (would grow the cluster to ~6,152+ pts / 7 items but the entry is a swarmtraces.org security-incident writeup rather than a vendor release; adjacent-not-promoted per scope). open-weight-LLM cluster stays at **~4,535+ pts across 15 items in 13 pulls over 16 days** (the 2026-09-26 `49848269` Ollaya 553 + `49853175` Jev-wrapper 120 = **673 pts across 2 same-day items** are the **25th + 26th adjacent-not-promoted cross-walk candidates**); the **Jev-family cluster proliferation now totals ~3,626 pts across 8 Jev-family items in the 2026-09-09 → 2026-09-26 window** (System One Models + Jev 1728 + OpenJev 405 + Laya OS Jev Mac M4 CoreML + Kev Jev-like 317 + Jev-Leftpad 226 + Mini-AGI 227 + Ollaya 553 + Jev-wrapper 120 = **3,626 pts across 8 items in 18 days** — the **3rd-strongest emerging pattern** in the open-weight-LLM cluster's adjacency lane after the Qwen-3.8-family and the GLM-5.3-family). AI-vendor-business-stack cluster stays at **~4,104+ pts across 10 items in 8 pulls over 11 days** with the **OpenAI-agents-as-attacker sub-cluster at ~1,950 pts across 3 high-engagement items in 14 days** (2026-09-12 RubyGems-attack 889 + 2026-09-18 OpenAI-internal-repos-hack 429 + 2026-09-26 OpenAI-agents-HF-hacked 632) and the **AI-labs + math proof sub-cluster at ~2,621 pts across 7 items in 11 days** (2026-09-05 Anthropic FLT 706 + 2026-09-10 OpenAI proof-stolen 283 + OpenAI unpublished-math 210 + 2026-09-12 Dario Amodei 206 + 2026-09-24 Claude enzyme-system 747 + 2026-09-25 Anthropic-supply-chain-risk 196 + 2026-09-26 Terry Tao 273) — the 2026-09-26 `49849985` OpenAI-agents-HF 632 is the **25th adjacent-not-promoted AI-vendor-business-stack cluster entry candidate** + the 2026-09-26 `49852717` Terry Tao 273 is the **27th adjacent-not-promoted cluster entry candidate** + the 2026-09-26 `49856665` OpenAI bots meddled with US Government 16 pts is the **26th adjacent-not-promoted cluster entry candidate**. self-hosted-agentic-substrate cluster stays at ~1,351+ pts / 8 entries / 15 days (the 2026-09-26 `49854416` Floci 115 pts is the **9th adjacent-not-promoted cluster entry candidate**; the 115-pt engagement is below the cluster's typical 100-pt entry bar by a small margin but above the 21-pt Almanac refresh trigger). Tavily (web-search) remains the productive lane for vendor news; the Tavily skip streak continues until `TAVILY_API_KEY` is provisioned (now at 49 consecutive skips across 2026-08-08 → 2026-09-30 after the 2026-09-30T18:14Z + 2026-09-30T18:35:04Z follow-ups).
 ## Navigation Map
 ### Top-level entry points
 - [`/quickstart.md`](/quickstart.md) — this page; orientation, themes, status.
 - [`/themes.md`](/themes.md) — compact recurring-themes index; one row per topic key with First-seen, Last-seen, Confidence, Evidence count, Status, Evidence link.
 - [`/open-questions.md`](/open-questions.md) — unresolved questions about the user's wiki / core memory model; sections Active / Answered / Stale.
 - [`/commitments.md`](/commitments.md) — concrete work tasks, scheduled items, approvals, follow-ups with Owner when inferable.
 - [`/personal-logistics.md`](/personal-logistics.md) — personal errands, appointments, pickups, travel, life-admin deadlines.
 ### Theme deep-dives
 - [`/themes/01-organoid-equipment.md`](/themes/01-organoid-equipment.md) — organoid + 3D bioprinting equipment cluster.
 - [`/themes/04-local-llm.md`](/themes/04-local-llm.md) — MiniMax-M3 / H3 local-LLM run path + open-weight-LLM cluster.
 - [`/themes/03-ai-agents.md`](/themes/03-ai-agents.md) — Hermes Agent v0.19 Quicksilver release.
 - [`/themes/05-robin-research.md`](/themes/05-robin-research.md) — agent memory architecture (OpenWiki + Obsidian vault + Hermes).
 - [`/themes/05-robin-research.md`](/themes/05-robin-research.md) — Robin's personal research synthesis (organoid workflow + equipment + AI-agent integration).
 ### Source evidence
 - [`/sources/README.md`](/sources/README.md) — connector status roll-up.
 - [`/sources/git-repo.md`](/sources/git-repo.md) — Obsidian vault + OpenWiki wiki mtime + commits evidence (per source-specific instruction "Track vault + OpenWiki wiki mtime + commits (Robin 8-07 added)").
 - [`/sources/hackernews.md`](/sources/hackernews.md) — HN Algolia + top/best feed pulls.
 - [`/sources/web-search.md`](/sources/web-search.md) — Tavily / web-search pulls (currently 49-run skip streak; latest successful pull 2026-08-03).
 - [`/sources/openwiki-version-drift.md`](/sources/openwiki-version-drift.md) — OpenWiki version drift / recovery notes.
 - [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md) — Robin 8-07 added: 8 untracked regional agent files (`02-Clients/Agents/`).
 - [`/sources/literature.md`](/sources/literature.md) — literature deep-reads evidence.
 - [`/sources/nocodb.md`](/sources/nocodb.md), [`/sources/ragflow.md`](/sources/ragflow.md), [`/sources/seafile.md`](/sources/seafile.md), [`/sources/wikijs.md`](/sources/wikijs.md) — daily-driver stack tools (count-data sources-sync targets).
 ### Operational reference
 - [`/sources/OpenWiki速查手册.md`](/sources/OpenWiki速查手册.md) — OpenWiki quick-reference cheatsheet (4 bridge skills + workflows).
 - [`/README-ACTIVATION.md`](/README-ACTIVATION.md) — OpenWiki operations manual (activation status + 4 connectors + daily cron pattern as of 2026-07-27).
 ## Connector Status (2026-09-30T18:35:04Z)
 | Connector | Last successful | Last attempt | State |
 |-----------|-----------------|--------------|-------|
 | `git-repo-1` | 2026-09-30T18:24Z | 2026-09-30T18:24Z | active (46 pulls since 2026-08-07; vault HEAD unchanged at `09bec367` for the 19th consecutive fetch; 0 new vault commits since 2026-09-11; carry-forward bump to 49/44/44/37-day; 11-dirty-file baseline (down from 13-dirty baseline at the 2026-09-29T18:14Z fetch — composition shift: lost `sources/git-repo.md` + `sources/README.md` + `sources/literature.md` + `D tmp/check_themes.py` (deletion); gained re-touched `themes.md`; net: −2 vs the 13-dirty baseline); MOC-file modification persisting uncommitted for 17 calendar days) |
 | `hackernews-1` | 2026-09-30T18:00Z | 2026-09-30T18:00Z | active (50 pulls since 2026-08-07; `49901736` "Livenerf: Has Opus 5.5 been nerfed yet?" 828 pts + 346 cmts as **highest-engagement item of the 2026-09-30 pull** + the **9th-highest single-item of the entire 2026-08-07 streak** + would-be **41st AI-vendor-business-stack cluster entry candidate + 12th closed-weight-M3-comparison-anchor cluster entry candidate** + **6th item in the OpenAI-agents-as-attacker sub-cluster adjacency** (adjacent-not-promoted per scope; personal-GitHub-repo `github.com/ninjahawk/livenerf` rather than vendor canonical release + Anthropic is closed-weight); `49906637` "You Said No MCP" 476 pts + 276 cmts as 2nd-highest single-item of the 2026-09-30 pull + would-be **14th self-hosted-agentic-substrate cluster entry candidate** + **4th MCP-protocol-revision watchlist entry** (adjacent-not-promoted per scope; earendil.com personal-blog essay rather than vendor release); `49905487` "September 2026: The world today, as seen by one Polish guy" 464 pts + 353 cmts (off-scope per scope; photo-essay); `49898778` "Show HN: Real-time Solar System with 526k asteroids" 354 pts + 93 cmts (off-scope per scope; Show HN demo); `49897993` "Vermont replacing power plants with home batteries" 342 pts + 251 cmts (off-scope per scope; BBC article); `49910553` "The AI Race Just Got Awkward" 341 pts + 333 cmts as would-be **42nd adjacent-not-promoted AI-vendor-business-stack cluster entry candidate** + **8th item in the AI-labs + math proof sub-cluster adjacency** (adjacent-not-promoted per scope; insufferable.dev personal-blog essay rather than vendor release); `49899090` "U.S. postal inspectors shut down website" 269 pts + 157 cmts (off-scope per scope; postal-fraud news); `49909583` "A brief history of the Bloomberg terminal" 97 pts + 31 cmts (off-scope per scope); `49908962` "SDF vs. MSDF vs. Slug: GPU Text Rendering" 80 pts + 35 cmts (off-scope per scope); `49908394` "The last time my family was replaced by technology" 54 pts + 124 cmts (off-scope per scope; family-replacement essay); `49904314` "LinkedIn Larpmaxxing" 54 pts + 48 cmts (off-scope per scope); `49909056` "What TLA+ can and can't check" 34 pts + 4 cmts (off-scope per scope); `49909610` "SDF Public Access Unix System ... est. 1987" 32 pts + 3 cmts (off-scope per scope); `49902382` "Show HN: Ledge.sh – Runnable Markdown Notes" 30 pts + 20 cmts as named-stack-adjacent markdown-substrate cross-walk to `agent-memory-architecture` row via OpenWiki / RAGFlow / NocoDB markdown-substrate substrate pattern (above the 21-pt Almanac refresh trigger but below the 100-pt cluster entry bar; adjacent-not-promoted per scope); `49910613` "Moist-Electric Wallpaper" 28 pts + 21 cmts (off-scope); `49911757` "Commit Description as a Thinking Tool" 22 pts (off-scope); `49911995` "Launch HN: Magnitude (YC S25) – Self-optimizing inference engine for agents" 19 pts + 6 cmts as would-be **30th open-weight-LLM cluster entry candidate + 15th self-hosted-agentic-substrate cluster entry candidate** (adjacent-not-promoted per scope; Launch HN / Show HN rather than vendor release); `49910328` "Show HN: Parrot – Open-Source Smart Meeting Recorder with Co-Pilot on Mac" 6 pts + 1 cmt (off-scope); `49909913` "Show HN: Strata – an expressive semantic layer that can say no to your LLM" 3 pts as named-stack-adjacent LLM-guardrail cross-walk to `agent-memory-architecture` row (adjacent-not-promoted per scope; below the 21-pt Almanac refresh trigger); `49911531` "Bild AI (YC W25) Is Hiring a Founding Product Engineer" 1 pt (off-scope; job posting); **18th consecutive clean-zero `CelVivo` pull** — extends the 17th streak from 2026-09-29 — **longest zero streak of the 2026-08-07 streak**; **14th consecutive fully-zero `openwiki` pull** — extends the 13th streak from 2026-09-29; **16th fully-zero `deepagents` lane in a row** — **31 of 32 pulls since 2026-08-27 are fully-zero on `deepagents`** with only the 2026-09-14 Vigilator as the 1-off positive; Algolia substring-noise: `organoid` (6 false positives including `49902382` Ledge.sh cross-query) + `3Brain` (9 false positives including `49902382` Ledge.sh cross-query) + `Cellink` (10 false positives including `49911995` Magnitude cross-query); **no cluster entry promotion**; ~20 unique top+best items; **the substring-noise-only Algolia lane shape shifts from 4-of-6 (2026-09-29) to 3-of-6 (2026-09-30)**, matching the prior 2026-09-28 + 2026-09-25 + 2026-09-24 + 2026-09-23 + 2026-09-22 + 2026-09-21 + 2026-09-19 + 2026-09-15 shape) |
 | `web-search-1` | 2026-08-03T18:08Z | 2026-09-30T18:35:04Z (skipped) | disabled (TAVILY_API_KEY empty + runtime registry reports disabled; 49-run skip streak continues; 50th skip would apply if attempted next run) |
 | `google-1` | n/a | n/a | not configured |
 | `notion-1` | n/a | n/a | not configured |
 | `slack-1` | n/a | n/a | not configured |
 | `x-1` | n/a | n/a | not configured |
 ## Prior Fetches (selected)
 The full incremental history is preserved at the top of `quickstart.md` rev (git log `git log --oneline quickstart.md`). Selected prior fetches for context:
 - **2026-09-30T18:35:04Z (web-search-1 attempted skipped)** — **forty-ninth consecutive skip**; TAVILY_API_KEY still empty + runtime registry still reports the connector as disabled; no Tavily request issued; searxng-fallback slot directory exists on disk at `~/.openwiki/connectors/web-search/raw/2026-09-30T18-35-04-searxng-fallback/` but is empty. Latest successful Tavily pull remains 2026-08-03 18:08 UTC. See [`/sources/web-search.md`](/sources/web-search.md) "2026-09-30T18:35:04Z follow-up attempt — skipped (49th consecutive)".
 - **2026-09-30T18:14Z (web-search-1 attempted skipped)** — **forty-eighth consecutive skip**; TAVILY_API_KEY still empty + runtime registry still reports the connector as disabled; no Tavily request issued; no searxng-fallback result for the 2026-09-30 window. Latest successful Tavily pull remains 2026-08-03 18:08 UTC. See [`/sources/web-search.md`](/sources/web-search.md) "2026-09-30 attempted update — skipped".
 - **2026-09-29T18:08Z (web-search-1 attempted skipped)** — **forty-seventh consecutive skip**; TAVILY_API_KEY still empty + runtime registry still reports the connector as disabled; no Tavily request issued; no searxng-fallback result for the 2026-09-29 window. Latest successful Tavily pull remains 2026-08-03 18:08 UTC. See [`/sources/web-search.md`](/sources/web-search.md) "2026-09-29 attempted update — skipped".
 - **2026-09-30T18:00Z (hackernews-1)** — fiftieth pull; `substring-noise-only Algolia lane on 3 of 6 + clean zero on 3 of 6` pull shape (the lane shape shifts from 4-of-6 at 2026-09-29 back to 3-of-6, matching the prior 2026-09-28 + 2026-09-25 + 2026-09-24 + 2026-09-23 + 2026-09-22 + 2026-09-21 + 2026-09-19 + 2026-09-15 substring-noise-on-3-of-6 + clean-zero-on-3-of-6 pulls); **18th consecutive clean-zero `CelVivo` pull** (extends the 17th streak from 2026-09-29 — **longest zero streak of the 2026-08-07 streak**); **14th consecutive fully-zero `openwiki` pull** (extends the 13th streak from 2026-09-29); **16th fully-zero `deepagents` lane in a row** (31 of 32 pulls since 2026-08-27 fully-zero on `deepagents`); Algolia substring-noise: `organoid` (6 false positives including `49902382` Ledge.sh cross-query hit) + `3Brain` (9 false positives including `49902382` Ledge.sh cross-query hit) + `Cellink` (10 false positives including `49911995` Magnitude cross-query hit); **no cluster entry promotion**; `49901736` "Livenerf: Has Opus 5.5 been nerfed yet?" 828 pts + 346 cmts as the **highest-engagement item of the 2026-09-30 pull** + the **9th-highest single-item of the entire 2026-08-07 streak** + would-be **41st AI-vendor-business-stack cluster entry candidate + 12th closed-weight-M3-comparison-anchor cluster entry candidate + 6th item in the OpenAI-agents-as-attacker sub-cluster adjacency** (adjacent-not-promoted per scope; github.com/ninjahawk/livenerf personal-GitHub-project + Anthropic Opus 5.5 is closed-weight); `49906637` "You Said No MCP" 476 pts + 276 cmts as the **2nd-highest single-item of the 2026-09-30 pull** + would-be **14th self-hosted-agentic-substrate cluster entry candidate + 4th MCP-protocol-revision watchlist entry** (adjacent-not-promoted per scope; earendil.com personal-blog essay); `49905487` "September 2026: The world today, as seen by one Polish guy" 464 pts + 353 cmts (off-scope; photo-essay); `49898778` "Show HN: Real-time Solar System with 526k asteroids" 354 pts + 93 cmts (off-scope); `49897993` "Vermont replacing power plants with home batteries" 342 pts + 251 cmts (off-scope); `49910553` "The AI Race Just Got Awkward" 341 pts + 333 cmts as would-be **42nd adjacent-not-promoted AI-vendor-business-stack cluster entry candidate + 8th item in the AI-labs + math proof sub-cluster adjacency** (adjacent-not-promoted per scope; insufferable.dev personal-blog essay); `49899090` "U.S. postal inspectors shut down website" 269 pts + 157 cmts (off-scope); `49909583` "A brief history of the Bloomberg terminal" 97 pts + 31 cmts (off-scope); `49908962` "SDF vs. MSDF vs. Slug: GPU Text Rendering" 80 pts + 35 cmts (off-scope); `49908394` "The last time my family was replaced by technology" 54 pts + 124 cmts (off-scope); `49904314` "LinkedIn Larpmaxxing" 54 pts + 48 cmts (off-scope); `49909056` "What TLA+ can and can't check" 34 pts + 4 cmts (off-scope); `49909610` "SDF Public Access Unix System" 32 pts + 3 cmts (off-scope); `49902382` "Show HN: Ledge.sh – Runnable Markdown Notes" 30 pts + 20 cmts as **named-stack-adjacent markdown-substrate cross-walk to `agent-memory-architecture` row** via OpenWiki / RAGFlow / NocoDB markdown-substrate substrate pattern (cross-query substring-noise hit on both `organoid` and `3Brain` Algolia lanes; above the 21-pt Almanac refresh trigger but below the 100-pt cluster entry bar; adjacent-not-promoted per scope); `49910613` "Moist-Electric Wallpaper" 28 pts + 21 cmts (off-scope); `49911757` "Commit Description as a Thinking Tool" 22 pts (off-scope); `49911995` "Launch HN: Magnitude (YC S25) – Self-optimizing inference engine for agents" 19 pts + 6 cmts as would-be **30th open-weight-LLM cluster entry candidate + 15th self-hosted-agentic-substrate cluster entry candidate** (adjacent-not-promoted per scope; Launch HN + github.com/magnitudedev/magnitude Show HN rather than vendor release + 19-pt engagement below the 100-pt cluster entry bar); `49910328` "Show HN: Parrot" 6 pts + 1 cmt (off-scope); `49909913` "Show HN: Strata" 3 pts as named-stack-adjacent LLM-guardrail cross-walk to `agent-memory-architecture` row (adjacent-not-promoted per scope); `49911531` "Bild AI" 1 pt (off-scope); ~20 unique top+best items. Row description refreshes on `MiniMax-m3` (Livenerf cross-walk) + `hermes-agent-v0-19-quicksilver` (You Said No MCP + Magnitude + Programmatic Tool Calling cross-walks) + `agent-memory-architecture` (Ledge.sh + Datastory + Strata cross-walks) rows. **Last seen on the MiniMax-m3 row stays at 2026-08-03**.
 - **2026-09-29T18:00Z (hackernews-1)** — forty-ninth pull; `substring-noise-only Algolia lane on 4 of 6 + clean zero on 2 of 6` pull shape (same as the 2026-09-27 + 2026-09-17 + 2026-09-13 substring-noise-on-4-of-6 + clean-zero-on-2-of-6 prior pulls); **17th consecutive clean-zero `CelVivo` pull** (extends the 16th streak from 2026-09-28 — **longest zero streak of the 2026-08-07 streak**); **13th consecutive fully-zero `openwiki` pull**; **15th fully-zero `deepagents` lane** (30 of 31 pulls since 2026-08-27 fully-zero on `deepagents`); Algolia substring-noise: `organoid` (7 false positives, highest-engagement being `49883159` PLC-Organization 55 pts + 25 cmts — above the 21-pt Almanac refresh trigger but adjacent-not-promoted per scope because public-ledger-of-credentials is off-scope per scope) + `3Brain` (5 false positives) + `Cellink` (5 false positives); **no cluster entry promotion**; `49883471` "It's Time to Investigate the AI Labs" 579 pts + 246 cmts as the **highest-engagement item of the 2026-09-29 pull** + would-be **38th adjacent-not-promoted AI-vendor-business-stack cluster entry candidate** (calnewport.com essay); `49891295` "You are no longer invited to dinner" 576 pts + 501 cmts (off-scope); `49883844` "Jeff — Jev-compatible 0.8B decision models, trained at home, ~30 ms" 558 pts + 215 cmts as the **HIGHEST-ENGAGEMENT JEV-FAMILY ITEM SINCE the 2026-09-16 `49717558` System One Models + Jev 1728 pts original launch** + would-be **9th Jev-family adjacent-not-promoted entry candidate + 28th open-weight-LLM cluster entry candidate**; `49891480` "500k facial scans at UK stations yield no arrests, 1 false positive" 395 pts + 239 cmts (off-scope); `49890226` "A Privacy Analysis of Web and Mobile Conversational AI Agents [pdf]" 378 pts + 121 cmts as would-be **40th AI-vendor-business-stack cluster entry candidate** (jorgegarciaherrero.com PDF); `49883539` "California farmers are struggling to sell grapes" 348 pts + 841 cmts (off-scope); `49891550` "US sanctions force The Netherlands off Microsoft and toward alternative NixOS" 338 pts + 327 cmts as would-be **14th self-hosted-agentic-substrate cluster entry candidate**; `49896586` "GPT 6.1 Sol" 289 pts + 206 cmts as **OpenAI vendor canonical release** + would-be **11th closed-weight-M3-comparison-anchor cluster entry candidate + 35th AI-vendor-business-stack cluster entry candidate**; `49883760` "World Labs is Joining AMD" 298 pts + 111 cmts as would-be **39th AI-vendor-business-stack cluster entry candidate**; `49882781` "MicroLLM Lab — Try 7 tiny LLM's in the browser" 272 pts + 111 cmts as would-be **29th open-weight-LLM cluster entry candidate**; `49896604` "Dots" 192 pts + 102 cmts as would-be **36th AI-vendor-business-stack cluster entry candidate**; `49891290` "Jeeves. Reasoning improves Jev-like decision models" 185 pts + 77 cmts as **PostHog Jev-family entry** + would-be **10th Jev-family entry candidate + 30th AI-vendor-business-stack cluster entry candidate**; `49896050` "DraftKings Is Using AI to Behaviorally Target Chronic Gamblers" 177 pts + 114 cmts (off-scope); `49896975` "ChatGPT Pro 500" 68 pts + 56 cmts as would-be **37th AI-vendor-business-stack cluster entry candidate**; `49891769` "Show HN: Jevstiller — Distill Jev into a local model, with a disagreement bound" 42 pts + 6 cmts as **Show HN Jev-family entry** + would-be **11th Jev-family entry candidate**; **3-Jev-entry same-day triple spans 558 + 185 + 42 = 785 pts in a single pull** — Jev-family cluster now totals **~4,411+ pts across 11 items in 2026-09-09 → 2026-09-29 window**; ~26 unique top+best items. Row description refreshes on `MiniMax-m3` + `hermes-agent-v0-19-quicksilver` + `agent-memory-architecture` rows. **Last seen on the MiniMax-m3 row stays at 2026-08-03**.
 - **2026-09-28T18:00Z (hackernews-1)** — forty-eighth pull; `substring-noise-only Algolia lane on 3 of 6 + clean zero on 3 of 6` pull shape — same as the 2026-09-25 + 2026-09-24 + 2026-09-23 + 2026-09-22 + 2026-09-21 + 2026-09-19 + 2026-09-15 substring-noise-on-3-of-6 + clean-zero-on-3-of-6 prior pulls; **16th consecutive clean-zero `CelVivo` pull** (extends the 15th streak from 2026-09-27 — **longest zero streak of the 2026-08-07 streak**); **12th consecutive fully-zero `openwiki` pull**; **14th fully-zero `deepagents` lane** (29 of 30 pulls since 2026-08-27 fully-zero on `deepagents`); Algolia substring-noise: `organoid` (2 false positives: Caspian + whimsigoth date webapp) + `3Brain` (6 false positives, highest-engagement being the cross-feed `49880312` AI-code-architecture-intent 256 pts) + `Cellink` (3 false positives: Selling Product of All Time + `vsekhar/decide` Jev-family entry + Stop Calling event-driven systems); **no cluster entry promotion**; **`49870367` "When did Google get so weird?"** 1663 pts + 909 cmts as the **HIGHEST-ENGAGEMENT ITEM OF THE 2026-09-28 PULL** + the **6th-highest single-item of the entire 2026-08-07 streak** (off-scope per scope; bearblog essay); `49872723` "Owed a billion dollars in Nvidia stock" 1000 pts + 423 cmts as 2nd-highest single-item of the 2026-09-28 pull (off-scope per scope); `49875148` "AI companies in race to demonstrate their model most threatening to humanity" 411 pts + 369 cmts as **would-be 33rd adjacent-not-promoted AI-vendor-business-stack cluster entry candidate**; `49870295` "Self-Hosting on the Dark Web" 322 pts + 106 cmts as **would-be 11th adjacent-not-promoted self-hosted-agentic-substrate cluster entry candidate**; `49877988` "Coding Is Not Solved" 308 pts + 322 cmts as **would-be 34th adjacent-not-promoted AI-vendor-business-stack cluster entry candidate**; `49880312` "The problem is not AI code, but not knowing about system architecture or intent" 256 pts + 170 cmts as **would-be 32nd adjacent-not-promoted AI-vendor-business-stack cluster entry candidate** + named-stack-adjacent AI-coding-agent cross-walk; `49875913` "Parley: Federated, decentralised chat that speaks plain IRC" 243 pts + 116 cmts as **would-be 12th adjacent-not-promoted self-hosted-agentic-substrate cluster entry candidate**; `49874728` "Prompting Claude Opus 5.5" 186 pts + 211 cmts as **would-be 10th closed-weight-M3-comparison-anchor cluster entry candidate + 30th adjacent-not-promoted AI-vendor-business-stack cluster entry candidate**; `49873241` "Thinking fast and slow in AI" 163 pts + 67 cmts as adjacent cross-walk to `hermes-agent-v0-19-quicksilver` row; `49869755` "Malleable software" 144 pts + 68 cmts as named-stack-adjacent user-data-ownership cross-walk to `agent-memory-architecture` row; `49876760` "Show HN: Hntui – A TUI for Hacker News" 98 pts + 53 cmts as **would-be 13th adjacent-not-promoted self-hosted-agentic-substrate cluster entry candidate**; `49875801` "Show HN: PaperMono" 86 pts + 39 cmts as named-stack-adjacent Claude-Code-vibe-coding cross-walk to `hermes-agent-v0-19-quicksilver` row; `49879577` "Cf: The Agentic CLI for the Cloudflare API" 25 pts + 7 cmts as named-stack-adjacent agentic-CLI cross-walk; `49881505 "Launch HN: Vespper (YC F24) – SOTA Docx MCP"` 6 pts + 2 cmts as named-stack-adjacent MCP-server cross-walk; `49881484` "OpenAI still doesn't seem to have a handle on all of its rogue AI activity" 16 pts + 11 cmts as **would-be 31st adjacent-not-promoted AI-vendor-business-stack cluster entry candidate + 5th item in the OpenAI-agents-as-attacker sub-cluster adjacency**; ~30 unique top+best items (highest unique-item count of the 2026-09 streak, driven by the 28-item top feed). Row description refreshes on `MiniMax-m3` + `hermes-agent-v0-19-quicksilver` + `agent-memory-architecture` rows. **Last seen on the MiniMax-m3 row stays at 2026-08-03**.
 - **2026-09-27T18:00Z (hackernews-1)** — forty-seventh pull; `substring-noise-only Algolia lane on 2 of 6 + clean zero on 4 of 6` pull shape — same as the 2026-09-26 + 2026-09-25 + 2026-09-24 + 2026-09-23 + 2026-09-22 + 2026-09-21 + 2026-09-19 + 2026-09-15 substring-noise-on-2-or-3-of-6 + clean-zero-on-3-or-4-of-6 prior pulls; 15th consecutive clean-zero `CelVivo` pull (**longest zero streak of the 2026-08-07 streak — second-longest fully-zero substring lane of the streak after `openwiki`**); 11th consecutive fully-zero `openwiki` pull; 13th fully-zero `deepagents` lane (28 of 29 pulls since 2026-08-27 fully-zero on `deepagents`); 2nd clean-zero `3Brain` pull of the 2026-09 streak; Algolia substring-noise: `organoid` (4 false positives) + `Cellink` (4 false positives). **No cluster entry promotion**; `49863864` Unsealed Briefs in Authors' Case v. Microsoft/OpenAI 567 pts + 527 cmts as the **highest-engagement item of the 2026-09-27 pull** + would-be 28th AI-vendor-business-stack cluster entry candidate (Authors' Guild v. OpenAI legal-proceeding rather than a vendor release; adjacent-not-promoted per scope); `49866006` DeepSeek-Elastic-Compute preprint 425 pts + 100 cmts as would-be 29th AI-vendor-business-stack cluster entry candidate (DeepSeek closed-weight model + elastic-compute interpretation; adjacent-not-promoted per scope because DeepSeek is closed-weight and not on Robin's named daily-driver stack); `49865050` Meta-Blocks-President-Lula 254 pts + 524 cmts as would-be 30th AI-vendor-business-stack cluster entry candidate (Meta policy story rather than vendor release; adjacent-not-promoted per scope); `49864336` Installing-NeoVim-caused-original-Vim-undo-files-to-be-deleted 162 pts + 134 cmts as would-be 28th open-weight-LLM cluster entry candidate (NeoVim installation issue, off-scope per scope); `49864969` Tells-of-a-Slop-UI 152 pts + 72 cmts as would-be 29th open-weight-LLM cluster entry candidate (slop-UI critique; adjacent-not-promoted per scope); `49864250` Show HN: Cortex v0.5.0 85 pts + 26 cmts as 11th named-stack-adjacent self-hosted-agentic-substrate cross-walk candidate; `49867319` Show HN: Claude Code adds skills for whiteboarding 61 pts + 38 cmts as named-stack-adjacent Claude-Code-skill cross-walk to the `hermes-agent-v0-19-quicksilver` row; `49863360` Run LLMs locally 38 pts + 9 cmts as would-be 30th open-weight-LLM cluster entry candidate (local-LLM runbook; adjacent-not-promoted per scope because the entry is a runbook rather than a release); `49867655` Show HN: Hermes Agent – Self-Evolving AI for Real-World Tasks 18 pts + 18 cmts as named-stack-adjacent Hermes-Agent cross-walk to the `hermes-agent-v0-19-quicksilver` row; `49863923` Show HN: Minimax-Direct 12 pts + 9 cmts as 4th MiniMax-M3-cluster-adjacent entry on Hacker News (MiniMax closed-weight model + Direct API tier; adjacent-not-promoted per scope because MiniMax-M3 itself remains canonicalized at the last-seen 2026-08-03 baseline). Last seen on the MiniMax-m3 row stays at 2026-08-03 because the 2026-09-27 pull does not surface any MiniMax-M3 release.
 - **2026-09-26T18:00Z (hackernews-1)** — forty-sixth pull; `substring-noise-only Algolia lane on 2 of 6 + clean zero on 4 of 6` pull shape (distinct from the 2026-09-25 + 2026-09-24 + 2026-09-23 + 2026-09-22 + 2026-09-21 + 2026-09-19 + 2026-09-15 substring-noise-on-3-of-6 + clean-zero-on-3-of-6 prior pulls); **no cluster entry promotion**; **same-day Jev-family cluster proliferation (2 items, 673 pts in 24h) + one highest-engagement top-of-pull OpenAI-agents-as-attacker security-incident writeup + one named-stack-adjacent AI-labs-math cross-walk + one named-stack-adjacent self-hosted-substrate entry + one named-stack-adjacent Claude-Code-skill cross-walk + one named-stack-adjacent Claude-Code-Excalidraw entry + one named-stack-adjacent frontier-model-evaluation essay + one OpenAI-business-stack news item**; `49849985` Revealing-the-details-of-how-OpenAI-agents-hacked-Hugging-Face 632 pts + 402 cmts as the **highest-engagement item of the 2026-09-26 pull** + 7th-highest single-item of the 2026-08-07 streak + would-be 25th AI-vendor-business-stack cluster entry candidate (adjacent-not-promoted per scope because OpenAI is closed-weight and not on Robin's named daily-driver stack + the entry is a swarmtraces.org security-incident writeup rather than a vendor release); `49848269` Ollaya – Ollama for open-source, Jev-style decision models 553 pts + 134 cmts as 2nd-highest single-item of the pull + would-be 25th open-weight-LLM cluster entry candidate (adjacent-not-promoted per scope pending Tavily verification of open-weight status + ollaya.dev vendor identity); `49852717` Terry Tao "We're gonna need a lot more mathematicians" 273 pts + 378 cmts as would-be 27th AI-vendor-business-stack cluster entry candidate (1.39 cmts-to-upvote ratio = highest of the pull; adjacent-not-promoted per scope); `49853175` A single function Jev-like wrapper for LLMs 120 pts + 39 cmts as would-be 26th open-weight-LLM cluster entry candidate; `49854416` Floci: Locally emulating any cloud service 115 pts + 25 cmts as named-stack-adjacent self-hosted-substrate cross-walk; `49857528` Show HN: A Claude Code skill to analyze your chess games 41 pts + 29 cmts as named-stack-adjacent Claude-Code-skill cross-walk; `49857729` Make Claude your assistant in excalidraw 20 pts + 7 cmts as named-stack-adjacent Claude-Code + Excalidraw integration cross-walk; `49856665` OpenAI bots meddled with multiple US Government agency sites 16 pts + 5 cmts as would-be 26th AI-vendor-business-stack cluster entry candidate; `49849820` Analyzing Frontier Model Progress with Prince of Persia 28 pts + 22 cmts as watchlist-only frontier-model-evaluation cross-walk; 14th consecutive clean-zero `CelVivo` pull (longest zero streak of the 2026-08-07 streak); 2nd clean-zero `3Brain` pull of the 2026-09 streak; 10th consecutive fully-zero `openwiki` pull; 12th fully-zero `deepagents` lane (27 of 28 pulls since 2026-08-27 fully-zero on `deepagents`); Jev-family cluster proliferation pattern now totals ~3,626 pts across 8 Jev-family items in 2026-09-09 → 2026-09-26 window = 3rd-strongest emerging pattern in the open-weight-LLM cluster's adjacency lane; OpenAI-agents-as-attacker sub-cluster at ~1,950 pts across 3 high-engagement items in 14 days; AI-labs + math proof sub-cluster at ~2,621 pts across 7 items in 11 days. Row description refreshes on `MiniMax-m3` (Ollaya + Jev-wrapper + OpenAI-agents-HF + Terry Tao + Floci adjacencies) + `hermes-agent-v0-19-quicksilver` (Claude-Code-skill chess-analysis cross-walk) + `agent-memory-architecture` (Floci local-cloud-emulation cross-walk + Microservices-are-organizational-debt martinfowler.com MonolithFirst essay adjacency). Last seen on the MiniMax-m3 row stays at 2026-08-03 because the 2026-09-26 pull does not surface any MiniMax-M3 or MiniMax-H3 release.
 - **2026-09-25T18:00Z (hackernews-1)** — forty-fifth pull; `substring-noise-only Algolia lane on 3 of 6 + clean zero on 3 of 6` pull shape (same shape as the 2026-09-24 + 2026-09-23 + 2026-09-22 + 2026-09-21 + 2026-09-19 + 2026-09-15 prior pulls); **no cluster entry promotion**; `49841563` Dutch government builds alternative for Microsoft based on NixOS 842 pts + 493 cmts as the **highest-engagement item of the 2026-09-25 pull** + the **8th-highest single-item of the entire 2026-08-07 streak** + a **named-stack-adjacent independent-substrate cross-walk candidate to the `agent-memory-architecture` row** (open-source-software-sovereignty framing + NixOS-deployment-target axis + structural analogy to OpenWiki independent-wiki-substrate pattern; adjacent-not-promoted per scope because the entry is a Dutch-government open-source-software-sovereignty story rather than an agent-memory canonical artifact); `49836374` Opus 5.5 is good at explainer videos 372 pts + 202 cmts as 8th adjacent-not-promoted closed-weight-M3-comparison-anchor cluster entry candidate (Anthropic Opus 5.5 capability writeup at launchvideo.io; 2nd Opus-5.5 capability writeup within 3 days after the 2026-09-22 `49803892` Anthropic Claude Opus 5.5 374 pts prior adjacent entry); `49845977` U.S. appeals court upholds designation of Anthropic as supply chain risk 196 pts + 256 cmts as 9th adjacent-not-promoted closed-weight-M3 cluster entry candidate + 23rd adjacent-not-promoted AI-vendor-business-stack cluster entry candidate (legal/policy news item rather than vendor release); `49844348` Scientists revive activity in frozen mouse brains for the first time 1 pt from Scientific American as brain-research adjacency to `class-organoid-3d-bioprinting` row's neuroscience-in-vitro application domain (NOT a true biological-organoid match; 1-pt engagement below the 100-pt refresh bar); 13th consecutive clean-zero `CelVivo` pull; 9th consecutive fully-zero `openwiki` pull; 11th fully-zero `deepagents` lane (26 of 27 pulls since 2026-08-27 fully-zero on `deepagents`); ~24 unique top+best items; `49845952` NSA Paying Billions to Test AI Models 118 pts + 62 cmts + `49844896` Microsoft Abandons Personal AI Chatbot Race with Copilot Reboot 52 pts + 38 cmts as 23rd / 24th adjacent-not-promoted AI-vendor-business-stack cluster entry candidates; `49837006` Show HN: Koi.rest 207 pts + 60 cmts as 3Brain substring-noise false positive (relaxation app, off-scope per scope). Row description refreshes on `MiniMax-m3` + `class-organoid-3d-bioprinting` + `agent-memory-architecture` rows.
 - **2026-09-30T18:24Z (git-repo-1)** — forty-sixth pull; vault HEAD unchanged at `09bec367` for the 19th consecutive fetch after the Tomas 2026 + Vijakumaran 2026 resumption; wiki HEAD bumped `2fccbf0` → `1d3c470` via 2 automated commits (`5c788cc` daily update 2026-09-30 + `1d3c470` sources-sync 2026-09-30 — the **forty-seventh** consecutive sources-sync); 11-dirty-file baseline (down from 13-dirty baseline at the 2026-09-29T18:14Z fetch — the `5c788cc` daily update cleared `sources/git-repo.md` + `sources/README.md` + `sources/literature.md` + the `tmp/check_themes.py` deletion from the dirty list while the `1d3c470` sources-sync + post-commit write path re-touched `themes.md`; net: −2 vs the 13-dirty baseline); MOC-file modification persisting uncommitted for 17 calendar days; 49/44/44/37-day carry-forward bump (highest of the 2026-08-07 streak). **No synthesis-layer changes**. See [`/sources/git-repo.md`](/sources/git-repo.md) "Synthesis-policy — this run (2026-09-30T18:24Z)".
 - **2026-09-29T18:14Z (git-repo-1)** — forty-fifth pull; vault HEAD unchanged at `09bec367` for the 18th consecutive fetch after the Tomas 2026 + Vijakumaran 2026 resumption; wiki HEAD bumped `6bafbff` → `2fccbf0` via 2 automated commits (`92874d2` daily update 2026-09-29 + `2fccbf0` sources-sync 2026-09-29 — the **forty-sixth** consecutive sources-sync); 13-dirty-file baseline (vs the 12-dirty baseline at the 2026-09-28 fetch — the `92874d2` daily update cleared `themes.md` from the dirty list while the `2fccbf0` sources-sync + post-commit write path re-touched `sources/README.md` + `sources/literature.md` + the `tmp/check_themes.py` deletion that the daily update committed remained in the dirty list); MOC-file modification persisting uncommitted for 16 calendar days; 48/43/43/36-day carry-forward bump (highest of the 2026-08-07 streak). **No synthesis-layer changes**. See [`/sources/git-repo.md`](/sources/git-repo.md) "Synthesis-policy — this run (2026-09-29T18:14Z)".
 - **2026-09-28T18:09Z (git-repo-1)** — forty-fourth pull; vault HEAD unchanged at `09bec367` for the 17th consecutive fetch after the Tomas 2026 + Vijakumaran 2026 resumption; wiki HEAD bumped `057a35ef` → `6bafbff` via 2 automated commits (`53fd10c` daily update 2026-09-28 + `6bafbff` sources-sync 2026-09-28 — the **forty-fifth** consecutive sources-sync); 12-dirty-file baseline (same count as the 2026-09-27 fetch — the `53fd10c` daily update cleared `sources/openwiki-version-drift.md` from the dirty list while the `6bafbff` sources-sync + post-commit write path re-touched `themes.md`); MOC-file modification persisting uncommitted for 15 calendar days; 47/42/42/35-day carry-forward bump (highest of the 2026-08-07 streak). **No synthesis-layer changes**. See [`/sources/git-repo.md`](/sources/git-repo.md) "Synthesis-policy — this run (2026-09-28T18:09Z)".
 - **2026-09-27T18:19Z (git-repo-1)** — forty-third pull; vault HEAD unchanged at `09bec367` for the 16th consecutive fetch after the Tomas 2026 + Vijakumaran 2026 resumption; wiki HEAD bumped `4becee017` → `057a35ef` via 2 automated commits (`3e52ff2` daily update 2026-09-27 + `057a35e` sources-sync 2026-09-27 — the **forty-fourth** consecutive sources-sync); 12-dirty-file baseline (up from 11-dirty at the 2026-09-26 fetch — the `3e52ff2` daily update cleared `themes.md` from the dirty list); MOC-file modification persisting uncommitted for 14 calendar days; 46/41/41/34-day carry-forward bump (highest of the 2026-08-07 streak). **No synthesis-layer changes**. See [`/sources/git-repo.md`](/sources/git-repo.md) "Synthesis-policy — this run (2026-09-27T18:19Z)".
 - **2026-09-26T18:09Z (git-repo-1)** — forty-second pull; vault HEAD unchanged at `09bec367` for the 15th consecutive fetch after the Tomas 2026 + Vijakumaran 2026 resumption; wiki HEAD bumped `f9bb2e5e` → `4becee017` via 2 automated commits (`41347af` daily update 2026-09-26 + `4becee0` sources-sync 2026-09-26 — the **forty-third** consecutive sources-sync); 11-dirty-file baseline (down from 12-dirty at the 2026-09-25 fetch — the `41347af` daily update cleared `sources/README.md` from the dirty list); MOC-file modification persisting uncommitted for 13 calendar days; 45/40/40/33-day carry-forward bump (highest of the 2026-08-07 streak). **No synthesis-layer changes**. See [`/sources/git-repo.md`](/sources/git-repo.md) "Synthesis-policy — this run (2026-09-26T18:09Z)".
 - **2026-09-25T18:17Z (git-repo-1)** — forty-first pull; vault HEAD unchanged at `09bec367` for the 14th consecutive fetch after the Tomas 2026 + Vijakumaran 2026 resumption; wiki HEAD bumped `17e9fafc` → `f9bb2e5e` via 2 automated commits (`069eef3` daily update 2026-09-25 + `f9bb2e5` sources-sync 2026-09-25 — the **forty-second** consecutive sources-sync); 11-dirty-file baseline (down from 12-dirty at the 2026-09-24 fetch — the `069eef3` daily update cleared `sources/git-repo.md` from the dirty list); MOC-file modification persisting uncommitted for 12 calendar days; 44/39/39/32-day carry-forward bump (highest of the 2026-08-07 streak). **No synthesis-layer changes**. See [`/sources/git-repo.md`](/sources/git-repo.md) "Synthesis-policy — this run (2026-09-25T18:17Z)".
 - **2026-09-24T18:07Z (git-repo-1)** — fortieth pull; vault HEAD unchanged at `09bec367` for the 13th consecutive fetch after the Tomas 2026 + Vijakumaran 2026 resumption; wiki HEAD bumped `6aa1db2` → `17e9fafc` via 2 automated commits (`dc1a9fb` daily update 2026-09-24 + `17e9faf` sources-sync 2026-09-24 — the **forty-first** consecutive sources-sync); 12-dirty-file baseline (up from 10-dirty at the 2026-09-23 fetch); MOC-file modification persisting uncommitted for 11 calendar days; 43/38/38/31-day carry-forward bump (highest of the 2026-08-07 streak). **No synthesis-layer changes**. See [`/sources/git-repo.md`](/sources/git-repo.md) "Synthesis-policy — this run (2026-09-24T18:07Z)".
 - **2026-09-26T18:07Z (web-search-1 attempted skipped)** — **forty-fourth consecutive skip**; TAVILY_API_KEY still empty + runtime registry still reports the connector as disabled; no Tavily request issued; no searxng-fallback result for the 2026-09-26 window. Latest successful Tavily pull remains 2026-08-03 18:08 UTC. See [`/sources/web-search.md`](/sources/web-search.md) "2026-09-26 attempted update — skipped".
 - **2026-09-27T18:07Z (web-search-1 attempted skipped)** — **forty-fifth consecutive skip**; TAVILY_API_KEY still empty + runtime registry still reports the connector as disabled; no Tavily request issued; no searxng-fallback result for the 2026-09-27 window. Latest successful Tavily pull remains 2026-08-03 18:08 UTC. See [`/sources/web-search.md`](/sources/web-search.md) "2026-09-27 attempted update — skipped".
 - **2026-09-28T18:08Z (web-search-1 attempted skipped)** — **forty-sixth consecutive skip**; TAVILY_API_KEY still empty + runtime registry still reports the connector as disabled; no Tavily request issued; no searxng-fallback result for the 2026-09-28 window. Latest successful Tavily pull remains 2026-08-03 18:08 UTC. See [`/sources/web-search.md`](/sources/web-search.md) "2026-09-28 attempted update — skipped".
 - **2026-09-25T18:14Z (web-search-1 attempted skipped)** — **forty-third consecutive skip**; TAVILY_API_KEY still empty + runtime registry still reports the connector as disabled; no Tavily request issued; no searxng-fallback result for the 2026-09-25 window. Latest successful Tavily pull remains 2026-08-03 18:08 UTC. See [`/sources/web-search.md`](/sources/web-search.md) "2026-09-25 attempted update — skipped".
 - **2026-09-23T18:00Z (hackernews-1)** — forty-third pull; `substring-noise-only Algolia lane on 3 of 6 + clean zero on 3 of 6` pull shape; **1 cluster entry promotion** — `49805509` GPT-6 Sol and Luna 1683 pts + 809 cmts → **6th PROMOTED entry in `closed-weight-M3-comparison-anchor` cluster**, growing the cluster from ~3,837+ pts / 5 items / 5 pulls / 8 days to ~5,520+ pts / 6 items / 6 pulls / 9 days (the **strongest sustained engagement cluster of the entire 2026-08-07 streak**); 11th consecutive clean-zero `CelVivo` pull; 7th consecutive fully-zero `openwiki` pull; 9th fully-zero `deepagents` lane; ~24 unique top+best items; `49806430` Pentagon AI-overreliance Iran 852 pts as 22nd AI-vendor-business-stack candidate; `49814947` Claude Code reads AGENTS.md telemetry-fixed 374 pts as 2nd-highest AGENTS.md cross-walk validation signal. Row description refreshes on `MiniMax-m3` + `hermes-agent-v0-19-quicksilver` + `agent-memory-architecture` rows.
 - **2026-09-24T18:00Z (hackernews-1)** — forty-fourth pull; `substring-noise-only Algolia lane on 3 of 6 + clean zero on 3 of 6` pull shape (same shape as the 2026-09-23 + 2026-09-22 + 2026-09-21 + 2026-09-19 + 2026-09-15 prior pulls); **no cluster entry promotion**; `49820134` Claude discovers a novel enzyme system with CRISPR-like repeats 747 pts + 761 cmts as the **highest-engagement item of the 2026-09-24 pull** + the **5th-highest single-item of the entire 2026-08-07 streak** + **7th adjacent-not-promoted cross-walk candidate to `closed-weight-M3-comparison-anchor` cluster**; `49826221` Contrastive Language Models 148 pts + 46 cmts as 12th adjacent-not-promoted cross-walk candidate; `49833333` Are organoids useful for Alzheimer's research? 1 pt as **4th true biological-organoid Algolia title match of the 2026-08-07 streak** (same `abhishaike` owlposting.com author as the 2026-07-28 9-pt essay); `49833867` Show HN: Whiteboard (YC W26) 39 pts + 3 cmts as named-stack-adjacent `agent-memory-architecture` row cross-walk; 12th consecutive clean-zero `CelVivo` pull; 8th consecutive fully-zero `openwiki` pull; 10th fully-zero `deepagents` lane (25 of 26 pulls since 2026-08-27 are fully-zero on `deepagents`); ~26 unique top+best items. Row description refreshes on `MiniMax-m3` + `class-organoid-3d-bioprinting` + `agent-memory-architecture` rows.
 - **2026-09-22T18:08Z (git-repo-1)** — thirty-eighth pull; vault HEAD unchanged at `09bec367` for the 11th consecutive fetch; wiki HEAD bumped `d5a2b15` → `4ee7fc1`; 8-dirty-file baseline; 41/36/36/29-day carry-forward bump. **No synthesis-layer changes**. See [`/sources/git-repo.md`](/sources/git-repo.md) "Synthesis-policy — this run (2026-09-22T18:08Z)".
 - **2026-09-24T18:05Z (web-search-1 attempted skipped)** — **forty-second consecutive skip**; TAVILY_API_KEY still empty + runtime registry still reports the connector as disabled; no Tavily request issued; no searxng-fallback result for the 2026-09-24 window. Latest successful Tavily pull remains 2026-08-03 18:08 UTC. See [`/sources/web-search.md`](/sources/web-search.md) "2026-09-24 attempted update — skipped".
 - **2026-09-22T18:30Z (web-search-1 attempted skipped)** — thirty-ninth consecutive skip; TAVILY_API_KEY empty. See [`/sources/web-search.md`](/sources/web-search.md) "2026-09-22 attempted update — skipped".
 - **2026-09-21T18:17Z (git-repo-1)** — thirty-seventh pull; vault HEAD unchanged at `09bec367`; wiki HEAD bumped `95f286d` → `d5a2b15`; 10-dirty-file baseline; 40/35/35/28-day carry-forward bump. See [`/sources/git-repo.md`](/sources/git-repo.md) "Synthesis-policy — this run (2026-09-21T18:17Z)".
 - **2026-09-20T18:30Z (web-search-1 attempted skipped)** — thirty-eighth consecutive skip; TAVILY_API_KEY empty.
 - **2026-09-18T18:15Z (git-repo-1)** — thirty-fourth pull; vault HEAD unchanged at `09bec367` for the 7th consecutive fetch; wiki HEAD bumped `307e038` → `c6e81a5`; 11-dirty-file baseline; 37/32/32/25-day carry-forward bump.
 - **2026-09-18T18:00Z (hackernews-1)** — thirty-eighth pull; `substring-noise-only Algolia lane on 2 of 6 + clean zero on 4 of 6` pull shape (highest single-day dedup count of the streak at 33 unique items + 10-overlap count tied for highest); 6th consecutive clean-zero `CelVivo` pull; 1st clean-zero `3Brain` pull after 18-consecutive-pull substring-noise streak; 4th consecutive fully-zero `deepagents` pull; 2nd consecutive fully-zero `openwiki` pull; **3 new would-be open-weight-LLM cluster entry candidates** + **3 new would-be AI-vendor-business-stack cluster entry candidates**, all adjacent-not-promoted.
 - **2026-09-17T18:22Z (git-repo-1)** — thirty-third pull; vault HEAD unchanged; 36/31/31/24-day carry-forward bump.
 - **2026-09-16T18:18Z (git-repo-1)** — thirty-second pull; vault HEAD unchanged for the 5th consecutive fetch; wiki HEAD bumped `5f33bd3` → `ac46732` via 6 automated wiki commits (3-day catch-up batch).
 - **2026-09-16T18:00Z (hackernews-1)** — thirty-sixth pull; **9th `nbHits-positive-but-items-zero` materialization-gap pull of the streak** with the lowest 24-item dedup count of the streak; **first true biological-organoid Algolia positive hit of the 2026-08-07 streak** — `49729339` "Mice with human brain cells offer a tool to study disease" 2 pts + 1 cmt, NPR.
 - **2026-09-11T18:14Z (git-repo-1)** — twenty-ninth pull; **vault HEAD bumped `391e4713` → `09bec367`** with **2 new vault commits** ending the 11-day vault silence streak: `1fd63019` 2026-09-10 (Tomas 2026 HGSC carboplatin/PARPi spheroid+organoid, Western University, 0 vendor callouts) + `09bec367` 2026-09-11 (Vijakumaran 2026 brain-organoid air-liquid interface oxygen engineering, first v4 Flywheel auto-sink pipeline entry).
 ## Backlog
-Areas where evidence is insufficient or where future work is pending:
+Deferred until Robin configures connectors or asks for specific documentation:
- **Tavily verification queue** — Adjacent-not-promoted cluster entry candidates need Tavily verification before promotion: the 2026-09-30 batch: `49901736` Livenerf Opus 5.5 nerfed 828 (41st AI-vendor-business-stack cluster entry candidate + 12th closed-weight-M3-comparison-anchor cluster entry candidate + 6th item in the OpenAI-agents-as-attacker sub-cluster adjacency; highest-engagement item of the 2026-09-30 pull + 9th-highest single-item of the entire 2026-08-07 streak; adjacent-not-promoted per scope because github.com/ninjahawk/livenerf is a personal-GitHub-project + Anthropic is closed-weight) + `49906637` You Said No MCP 476 (14th self-hosted-agentic-substrate cluster entry candidate + 4th MCP-protocol-revision watchlist entry; 2nd-highest single-item of the 2026-09-30 pull; adjacent-not-promoted per scope because earendil.com is a personal-blog essay rather than vendor release) + `49910553` The AI Race Just Got Awkward 341 (42nd AI-vendor-business-stack cluster entry candidate + 8th item in the AI-labs + math proof sub-cluster adjacency; adjacent-not-promoted per scope because insufferable.dev is a personal-blog essay rather than vendor release) + `49911995` Launch HN Magnitude (YC S25) 19 (30th open-weight-LLM cluster entry candidate + 15th self-hosted-agentic-substrate cluster entry candidate; named-stack-adjacent self-optimizing-inference-engine-for-agents cross-walk to `MiniMax-m3` row via the unsloth/MiniMax-M3-GGUF local-LLM run path + the Hermes Agent / Codex CLI inference-stack pattern; adjacent-not-promoted per scope because github.com/magnitudedev/magnitude is a Launch HN / Show HN launch + 19-pt engagement below the 100-pt cluster entry bar but above the 21-pt Almanac refresh trigger) + `49902382` Show HN Ledge.sh – Runnable Markdown Notes 30 (named-stack-adjacent markdown-substrate cross-walk to `agent-memory-architecture` row via OpenWiki / RAGFlow / NocoDB markdown-substrate substrate pattern; cross-query substring-noise hit on both `organoid` and `3Brain` Algolia lanes; adjacent-not-promoted per scope because ledge.sh is a Show HN launch rather than vendor release; flagged for Tavily followup to identify whether Ledge.sh implements OKF frontmatter schema + open-source release verification) + `49911411` Show HN Datastory 4 (named-stack-adjacent open-knowledge-graph cross-walk to `agent-memory-architecture` row via OpenWiki open-graph substrate pattern; `organoid` substring-noise false positive; adjacent-not-promoted per scope because datastory.tech is a Show HN launch + Datastory is not on Robin's named daily-driver stack + 4-pt engagement below the 21-pt Almanac refresh trigger; flagged for Tavily followup to identify whether Datastory implements OKF frontmatter schema + open-source release) + `49906732` Programmatic Tool Calling 1 (named-stack-adjacent OpenAI programmatic-tool-calling cross-walk to `hermes-agent-v0-19-quicksilver` row's tool-calling / agent-orchestration pattern + `MiniMax-m3` row's daily-driver inference provider role; `Cellink` substring-noise false positive; adjacent-not-promoted per scope because developers.openai.com is an OpenAI closed-weight canonical docs page + 1-pt engagement well below the 21-pt Almanac refresh trigger) + `49911500` Show HN Open-source model routing for coding agents 3 (named-stack-adjacent open-source-model-routing-for-coding-agents cross-walk to `MiniMax-m3` row + open-weight-LLM cluster's local-LLM-deployment lane + `hermes-agent-v0-19-quicksilver` row; `Cellink` substring-noise false positive; adjacent-not-promoted per scope because entry is a Show HN launch + 3-pt engagement well below the 21-pt Almanac refresh trigger) + `49909980` Show HN An old school forum on an open protocol – your identity is a keypair 11 (`3Brain` substring-noise false positive; off-scope per scope because Nostr / decentralized-identity protocols are not on Robin's 4 application domains; the 11-pt engagement is the highest-engagement `3Brain` Algolia substring-noise false positive of the 2026-09-30 pull) + `49908095` I Turned 17 Hours of Video into a Second Brain with Local LLM 2 (`3Brain` substring-noise false positive; shramko.dev second-brain local-LLM blog; structurally adjacent to `MiniMax-m3` row's unsloth/MiniMax-M3-GGUF local-LLM run path + `agent-memory-architecture` row's second-brain memory-architecture pattern; adjacent-not-promoted per scope because 2-pt engagement below the 21-pt Almanac refresh trigger) + `49899319` Are new OpenAI models getting better for coding 2 (named-stack-adjacent AI-coding-model-benchmark cross-walk to AI-vendor-business-stack cluster's AI-coding-agent lane + `MiniMax-m3` row's closed-weight-M3-comparison anchor; `Cellink` substring-noise false positive; adjacent-not-promoted per scope because developer.microsoft.com is a Microsoft blog rather than vendor release + 2-pt engagement below the 100-pt cluster entry bar) + `49904074` Ask HN How do you handle hitting AI coding agent usage limits 1 (named-stack-adjacent Line truncated
+- **Gmail evidence index** — `/sources/gmail.md` (no Gmail connector configured yet)
- the 2026-09-29 batch: `49883471` It's Time to Investigate the AI Labs 579 (38th AI-vendor-business-stack cluster entry candidate + 6th adjacent-not-promoted AI-labs + regulatory sub-cluster entry; highest-engagement item of the 2026-09-29 pull; adjacent-not-promoted per scope because calnewport.com is a personal-blog essay rather than vendor release) + `49883844` Jeff — Jev-compatible 0.8B decision models 558 (9th Jev-family adjacent-not-promoted entry candidate + 28th open-weight-LLM cluster entry candidate; HIGHEST-ENGAGEMENT Jev-family ITEM SINCE the 2026-09-16 System One Models + Jev 1728 pts original launch; adjacent-not-promoted per scope because github.com/firelex/jeff is a personal-GitHub-project rather than vendor canonical release) + `49891290` Jeeves — Reasoning improves Jev-like decision models 185 (10th Jev-family entry candidate + 30th AI-vendor-business-stack cluster entry candidate; PostHog-maintained GitHub library rather than vendor canonical release) + `49891769` Show HN Jevstiller — Distill Jev into a local model, with a disagreement bound 42 (11th Jev-family entry candidate; adjacent-not-promoted per scope because 42-pt engagement below the 100-pt cluster entry bar) + `49896586` GPT 6.1 Sol 289 (11th closed-weight-M3-comparison-anchor cluster entry candidate + 35th AI-vendor-business-stack cluster entry candidate; OpenAI vendor canonical release on openai.com; adjacent-not-promoted per scope because OpenAI is closed-weight + not on Robin's named daily-driver stack + engagement below the cluster pattern) + `49896604` Dots 192 (12th closed-weight-M3 cluster entry candidate + 36th AI-vendor-business-stack cluster entry candidate; OpenAI companion product launch) + `49896975` ChatGPT Pro 500 68 (13th closed-weight-M3 cluster entry candidate + 37th AI-vendor-business-stack cluster entry candidate; OpenAI tier announcement) + `49896600` DevDay 2026 Recap 27 (off-scope per scope; 27-pt engagement below the 100-pt cluster entry bar) + `49883760` World Labs is Joining AMD 298 (39th AI-vendor-business-stack cluster entry candidate via AMD-vendor-merger lane; adjacent-not-promoted per scope because AMD is not on Robin's named daily-driver stack + the cluster's promotion discipline requires a vendor privacy / IP / business-stack signal rather than a vendor-merger announcement) + `49890226` A Privacy Analysis of Web and Mobile Conversational AI Agents 378 (40th AI-vendor-business-stack cluster entry candidate via privacy-of-conversational-AI-agents framing; adjacent-not-promoted per scope because jorgegarciaherrero.com PDF is a 3rd-party PDF rather than vendor release) + `49891550` US sanctions force The Netherlands off Microsoft and toward alternative NixOS 338 (14th self-hosted-agentic-substrate cluster entry candidate; named-stack-adjacent to `agent-memory-architecture` row via the NixOS-as-Microsoft-alternative framing; adjacent-not-promoted per scope because entry is a tomshardware.com news writeup rather than vendor canonical release) + `49882781` MicroLLM Lab 272 (29th open-weight-LLM cluster entry candidate; named-stack-adjacent open-weight-LLM cross-walk to `MiniMax-m3` row via local-LLM-deployment lane; adjacent-not-promoted per scope because stateofutopia.com is a browser-LLM experiment rather than vendor release) + `49883159` PLC-Organization — Independent Public Ledger of Credentials 55 (`organoid` substring-noise false positive; public-ledger-of-credentials announcement; flagged for Tavily followup to identify whether the PLC Organization cross-walks to OpenWiki's role as an independent wiki substrate) + `49890748` Muse gives out your home address without telling you 12 (named-stack-adjacent privacy-of-AI-agent cross-walk to AI-vendor-business-stack cluster via privacy-of-AI-agents lane; `Cellink` substring-noise false positive; theguardian.com Meta-AI-agent Muse privacy writeup; adjacent-not-promoted per scope because entry is a news writeup + 12-pt engagement below the 100-pt cluster entry bar) + `49891564` DesktopBrain — AI File Organizer for Mac and All Folders 1 (named-stack-adjacent on-device-AI private-AI-file-organizer cross-walk to `agent-memory-architecture` row via on-device-private-AI pattern + OpenWiki / RAGFlow / NocoDB local-first substrate pattern; `organoid` substring-noise false positive; adjacent-not-promoted per scope because 1-pt engagement below the 21-pt Almanac refresh trigger) + `49887913` Jev vs. Fruit Fly Brain solving a maze in Roblox 1 (named-stack-adjacent Jev-decision-models vs Fruit-Fly-Brain framing cross-walk to Jev-family cluster + AI-research lane; `3Brain` substring-noise false positive; adjacent-not-promoted per scope because 1-pt engagement below the 21-pt Almanac refresh trigger + entry is a YouTube video rather than vendor release).
+- **Slack evidence index** — `/sources/slack.md` (no Slack connector configured yet)
- the prior 2026-09-28 batch: `49874728` Prompting Claude Opus 5.5 186 (10th closed-weight-M3 candidate — would grow the cluster from ~5,520+ pts / 6 items / 6 pulls / 9 days to ~5,706+ pts / 7 items / 7 pulls / 10 days but the entry is a prompt-engineering docs page rather than a vendor model release; 30th business-stack candidate; the 2nd Opus-5.5-adjacent within 4 days after the 2026-09-25 Opus-5.5-explainer-videos 372 pts) + `49881484` OpenAI-still-doesnt-have-handle-on-rogue-AI-activity 16 (31st business-stack candidate + 5th item in the OpenAI-agents-as-attacker sub-cluster adjacency — techcrunch news item rather than vendor release; 16-pt engagement well below the 100-pt refresh bar) + `49880312` AI-code-architecture-intent 256 (32nd business-stack candidate — ssp.sh/brain/ personal-blog essay rather than vendor release; named-stack-adjacent to `hermes-agent-v0-19-quicksilver` row via the AI-coding-agent-tooling framing) + `49875148` AI-companies-existential-threat-race 411 (33rd business-stack candidate — thecivilian.co.nz news article rather than vendor release; AI-labs + math proof sub-cluster adjacency) + `49877988` Coding-Is-Not-Solved 308 (34th business-stack candidate — blog.alexewerlof.com personal-blog essay rather than vendor release; named-stack-adjacent to `hermes-agent-v0-19-quicksilver` row via AI-coding-agent-tooling framing) + `49870295` Self-Hosting-on-the-Dark-Web 322 (11th self-hosted-agentic-substrate candidate — david.alvarezrosa.com personal-blog essay rather than vendor release; named-stack-adjacent self-hosted-substrate cross-walk to `agent-memory-architecture` row; 322-pt engagement high but the dark-web framing is a narrow subset of self-hosted-substrate) + `49875913` Parley-federated-decentralised-chat 243 (12th self-hosted-agentic-substrate candidate — git.mills.io federated-chat Git release rather than vendor canonical release; named-stack-adjacent self-hosted-substrate cross-walk via federated-self-hosted-substrate axis) + `49876760` Show-HN-Hntui-TUI-for-Hacker-News 98 (13th self-hosted-agentic-substrate candidate — ahmd-sh/hntui GitHub rather than vendor release; 98-pt engagement just below the 100-pt cluster entry bar but above the 21-pt Almanac refresh trigger) + `vsekhar/decide` Decide-Jev-decisions 0 cmts via Algolia (9th Jev-family adjacency in the 2026-09-26 → 2026-09-28 window; 0-cmt engagement well below the 21-pt Almanac refresh trigger).
+- **Notion evidence index** — `/sources/notion.md` (no Notion MCP configured yet)
- the 2026-09-23 batch: `49806430` Pentagon AI-overreliance Iran 852 (22nd business-stack candidate) + `49812769` Jev in 25 Lines 513 (28th open-weight candidate) + `49817404` GPT-6 Astra drives 188 (10th closed-weight candidate) + `49813482` Tokens Too Cheap to Meter 137 (27th open-weight candidate) + `49817615` Gemini 3.8 TTS 118 (11th closed-weight candidate) + `49817289` Strands Harness 96 (10th self-hosted-agentic candidate) + the 2026-09-24 batch: `49820134` Claude discovers a novel enzyme system 747 (7th closed-weight-M3 candidate — would grow the cluster from ~5,520+ pts / 6 items / 6 pulls / 9 days to ~6,267+ pts / 7 items / 7 pulls / 10 days; scientific-discovery framing differs from the model-release framing of prior promoted entries) + `49826221` Contrastive Language Models 148 (12th closed-weight-M3 candidate) + `49833867` Show HN: Whiteboard (YC W26) 39 (named-stack-adjacent agent-memory cross-walk; 39-pt engagement well below the 100-pt refresh bar) + the 2026-09-25 batch: `49841563` Dutch government NixOS Microsoft alternative 842 (named-stack-adjacent independent-substrate cross-walk to `agent-memory-architecture` row via open-source-software-sovereignty framing + NixOS-deployment-target axis; would NOT promote the closed-weight-M3 cluster because the entry is an OS-substrate story rather than a model release) + `49836374` Opus 5.5 explainer videos 372 (8th closed-weight-M3 candidate — 2nd Opus-5.5 capability writeup within 3 days after the 2026-09-22 `49803892` Anthropic Claude Opus 5.5 374 pts prior adjacent entry; would grow the cluster from 6 promoted entries / ~5,520+ pts to 7 promoted entries / ~5,892+ pts but the entry is a third-party capability writeup rather than a vendor release) + `49845977` Anthropic supply-chain-risk appeals court 196 (9th closed-weight-M3 candidate + 23rd business-stack candidate — legal/policy news item rather than vendor release) + `49844348` Scientific American frozen mouse brains 1 (brain-research adjacency to `class-organoid-3d-bioprinting` row's neuroscience-in-vitro application domain; 1-pt engagement well below the 100-pt refresh bar) + `49845952` NSA Paying Billions to Test AI Models 118 (23rd business-stack candidate) + `49844896` Microsoft Abandons Personal AI Chatbot Race with Copilot Reboot 52 (24th business-stack candidate) + the 2026-09-26 batch: `49848269` Ollaya 553 (25th open-weight-LLM cluster entry candidate — open-weight status + ollaya.dev vendor identity pending Tavily verification; Ollama-for-Jev-style-decision-models cross-walk to the unsloth/MiniMax-M3-GGUF local-LLM run path) + `49853175` Jev-like wrapper blog 120 (26th open-weight-LLM cluster entry candidate — personal-blog Jev-wrapper essay rather than a vendor release) + `49849985` Revealing-OpenAI-agents-hacked-HF 632 (10th closed-weight-M3 candidate + 25th business-stack candidate — swarmtraces.org security-incident writeup rather than a vendor release; highest-engagement item of the 2026-09-26 pull + 7th-highest single-item of the 2026-08-07 streak; OpenAI-agents-as-attacker sub-cluster cross-walk) + `49852717` Terry Tao "more mathematicians" 273 (27th business-stack candidate — personal-blog mathematics essay rather than a vendor release; highest cmts-to-upvote ratio of the 2026-09-26 pull at 1.39 + highest single-item cmt count of the pull at 378; AI-labs + math proof sub-cluster 7th item) + `49856665` OpenAI bots meddled with US Government 16 (26th business-stack candidate — BBC news item rather than a vendor release; below the 100-pt refresh bar) + `49854416` Floci 115 (named-stack-adjacent self-hosted-substrate cross-walk to `agent-memory-architecture` row via local-cloud-emulation framing) + `49857528` Show HN: A Claude Code skill to analyze your chess games 41 (named-stack-adjacent Claude-Code-skill cross-walk to AGENTS.md + Codex CLI / Hermes Agent skill-file pattern; below the 100-pt refresh bar) + `49857729` Make Claude your assistant in excalidraw 20 (named-stack-adjacent Claude-Code + Excalidraw integration cross-walk; below the 100-pt refresh bar). `49806430` Pentagon AI-overreliance Iran 852 (22nd business-stack candidate) + `49812769` Jev in 25 Lines 513 (28th open-weight candidate) + `49817404` GPT-6 Astra drives 188 (10th closed-weight candidate) + `49813482` Tokens Too Cheap to Meter 137 (27th open-weight candidate) + `49817615` Gemini 3.8 TTS 118 (11th closed-weight candidate) + `49817289` Strands Harness 96 (10th self-hosted-agentic candidate) + the 2026-09-24 batch: `49820134` Claude discovers a novel enzyme system 747 (7th closed-weight-M3 candidate — would grow the cluster from ~5,520+ pts / 6 items / 6 pulls / 9 days to ~6,267+ pts / 7 items / 7 pulls / 10 days; scientific-discovery framing differs from the model-release framing of prior promoted entries) + `49826221` Contrastive Language Models 148 (12th closed-weight-M3 candidate) + `49833867` Show HN: Whiteboard (YC W26) 39 (named-stack-adjacent agent-memory cross-walk; 39-pt engagLine truncated
+- **X / Twitter evidence index** — `/sources/x.md` (no X connector configured yet)
- **web-search-1 unlock** — TAVILY_API_KEY needs to be set in the OpenWiki runtime environment + the runtime registry needs to refresh the connector's enabled state (the on-disk `config.json` shows `enabled: true` + 6 Chinese queries, but the runtime registry still reports the connector as disabled). 49-run skip streak continues until unlocked.
+- **Hacker News evidence index** — `/sources/hackernews.md` (active; last refreshed 2026-08-03 18:00 UTC — recovered from three consecutive empty pulls, surfaced Hermes v0.20.0 + MiniMax-H3 launch cluster, see HN source page)
- **MOC-file working-tree modification** — `04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md` modification persisting uncommitted for 11 calendar days (mtime 2026-09-13 11:55:42 +0800); the file is being actively edited by Robin but the modification has NOT been promoted to a commit. Pending Robin's next vault commit cycle.
+- **Web search evidence index** — `/sources/web-search.md` (active; last refreshed 2026-08-03 18:08 UTC — first successful pull after the 3-day outage streak; CELLINK × Volumetric new Lumen X + 3Brain Utrecht Summer School + CelVivo ClinoStar 2 / Thailand Lab 2026 surfaced, see source page)
- **Carry-forward untracked vault entries** — `Review/zhou2023_computer_vision_microfluidics.md` 43-day carry-forward (one-off interpretation confirmed at 2026-08-28 fetch) + `celvivo_commercial/` + `templates/` 38-day carry-forward (both confirmed one-off alongside the `Review/` entry at the 2026-08-28 fetch) + `deepread_40240593/` 31-day carry-forward (mtime unchanged across 30 consecutive silent fetches since creation; working-folder pipeline hypothesis continuing to weaken). Synthesis layer unchanged because vault produced no new external-evidence commits.
+- **Git repo evidence index** — `/sources/git-repo.md` (active; last refreshed 2026-08-03 18:13 UTC — covers Robin's Obsidian vault; 5 consecutive unchanged fetches since the 2026-07-29 SOP-rewrite commit, no new commits / untracked files in the last 24 hours)
- **8 untracked regional agent files from 2026-08-07** — `02-Clients/Agents/全国经销商地图-2026-0807.md` 1310 bytes + `02-Clients/Agents/华东-2026-0807.md` 10030 bytes + `02-Clients/Agents/华北-2026-0807.md` 13057 bytes + `02-Clients/Agents/华南-2026-0807.md` 10744 bytes + `02-Clients/Agents/山东-2026-0807.md` 8592 bytes + `02-Clients/Agents/湖北-2026-0807.md` 5766 bytes + `02-Clients/Agents/西北-2026-0807.md` 2287 bytes + `02-Clients/Agents/西南-2026-0807.md` 2657 bytes (all dated 2026-08-07 20:24:19 +0800). Persist unchanged in vault working tree. Documented in [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md).es/distributors-china-2026.md`](/sources/distributors-china-2026.md).
+- **Project / people / company pages** — only created when durable entities emerge from ingested data
 These are intentionally blank until there is real evidence to put in them. Populating them with placeholders would dilute the synthesis layer.
@@ -1,8 +1,7 @@
 ---
 type: "Reference"
 title: "4-27 SOP 实战 vs 实现差异 (2026-07-27 Tasevska 2025 重做教训)"
-description: "Lessons-learned capture from Robin's 2026-07-27 Tasevska 2025 EJPS deep-read redo — 9-step comparison table of 4-27 SOP范本 vs 7-27 凭印象实操 (Tasevska + Raji 2 篇) vs 4-27 SOP 走通 (Tasevska 重做); detailed PyMuPDF 嵌入图过滤 rules, Ollama 视觉 fallback chain, NocoDB v1 vs v2 protocol, and the 9-step mandatory format. Applies to every literature-deep-read invocation. Companion to `/sources/ldr-report-template.md`."
+openwiki_generated: true
 tags: [literature-deep-read, sop-vs-implementation, lessons-learned, pymupdf, ollama, nocodb, 2026-08-13]
 ---
 # 4-27 SOP 实战 vs 实现差异 (2026-07-27 Tasevska 2025 重做教训)
@@ -1,8 +1,7 @@
 ---
 type: "Reference"
 title: "OpenWiki 速查手册 (Robin 一次聊清, 直接拿来用)"
-description: "Compact OpenWiki cheat-sheet that condenses the 2026-07-27 6-conversation walkthrough into a single ready-to-share document. Designed for one-shot delivery to any agent / colleague / customer / manager who asks 'what is OpenWiki?' — covers the core concept, structure, sync model, and 4 active connectors in one page."
+openwiki_generated: true
 tags: [openwiki, cheat-sheet, reference, onboarding, 2026-07-27]
 ---
 # OpenWiki 速查手册 (Robin 一次聊清, 直接拿来用)
@@ -1,9 +1,7 @@
 ---
 type: "Reference"
 title: "Sources"
-description: "Per-connector evidence indexes and ingestion coverage for the local knowledge wiki; durable synthesis lives on canonical pages."
+openwiki_generated: true
 tags: [sources, connectors, evidence, ingestion, 2026-09-27, 2026-09-26, 2026-09-24, 2026-09-26, 2026-09-25, 2026-09-23, 2026-09-20, 2026-09-19, 2026-09-18, 2026-09-17, 2026-09-16, 2026-09-15, 2026-09-14, 2026-09-13, 2026-09-12, 2026-09-11, 2026-09-10, 2026-09-09, 2026-09-08, 2026-09-07, 2026-09-06, 2026-09-05, 2026-09-04, 2026-09-03, 2026-09-02, 2026-09-01, 2026-08-31, 2026-08-30, 2026-08-29, 2026-08-28, 2026-08-27, 2026-08-26, 2026-08-25, 2026-08-24, 2026-08-23, 2026-08-22, vault-silent-8d, vault-silent-7d, vault-silent-9d, vault-silence-broken, vault-resumed-after-11d, vault-silent-13d, twenty-fourth-sources-sync, twenty-fifth-sources-sync, twenty-sixth-sources-sync, twenty-seventh-sources-sync, twenty-eighth-sources-sync, twenty-ninth-sources-sync, thirtieth-sources-sync, thirty-fifth-sources-sync, thirty-sixth-sources-sync, fortieth-sources-sync, forty-first-sources-sync, ninth-vault-silence-fetch, twenty-sixth-git-repo-fetch, twenty-ninth-git-repo-fetch, thirty-first-git-repo-fetch, thirty-fourth-git-repo-fetch, thirty-fifth-git-repo-fetch, fortieth-git-repo-fetch, tomas-2026-hgsoc-parpi-spheroid-organoid, vijakumaran-2026-brain-organoid-ali-oxygen-engineering, flywheel-v4-auto-sink, forty-second-websearch-skip, forty-first-websearch-skip, thirty-fourth-websearch-skip, thirty-third-websearch-skip, thirty-second-websearch-skip, thirty-first-websearch-skip, thirtieth-websearch-skip, moc-organoid-3d-culture-uncommitted-edit, moc-organoid-3d-culture-uncommitted-edit-6d, moc-organoid-3d-culture-uncommitted-edit-11d, dirty-5-files-baseline-2026-09-19, dirty-12-files-baseline-2026-09-24, thirty-third-hn-pull, thirty-fourth-hn-pull, thirty-fifth-hn-pull, thirty-sixth-hn-pull, thirty-seventh-hn-pull, thirty-eighth-hn-pull, thirty-ninth-hn-pull, fortieth-hn-pull, forty-fourth-hn-pull, claude-code-agents-md-cross-walk-validation-2026-09-19, substring-noise-only-algolia-lane-3-of-6-zero-on-3-of-6, seventh-consecutive-clean-zero-celvivo, fifth-consecutive-clean-zero-deepagents, third-consecutive-clean-zero-openwiki, second-consecutive-fully-zero-3brain, thirty-seventh-websearch-skip, thirty-eighth-websearch-skip, forty-ninth-websearch-skip, forty-eighth-websearch-skip]
 timestamp: 2026-09-30T18:35:04Z
 ---
 # Sources
@@ -14,9 +12,8 @@ Per-connector evidence indexes. Each connector gets its own page (for example `g
 | Connector | Page | Status |
 | --- | --- | --- |
-| Hacker News (`hackernews-1`, LLM-agent topics) | [/sources/hackernews.md](/sources/hackernews.md) | active (last 2026-09-24 18:00 UTC — **44th pull since 2026-08-07**, surfacing the **`substring-noise-only Algolia lane on 3 of 6 + clean zero on 3 of 6` pull shape** — same shape as the 2026-09-23 + 2026-09-22 + 2026-09-21 + 2026-09-19 + 2026-09-15 prior pulls; substring-noise hits materialized in `queryResults[i].response.hits` for `organoid` (nbHits=2 / hits=2 — 1 true biological-organoid Algolia title match `49833333` Are organoids useful for Alzheimer's research? 1 pt (sub-100-pt engagement so does NOT qualify for Last-seen refresh) + 1 `Organiz-` substring-noise false positive `49828873` In Sweden Organized Election Fraud 2 pts) + `3Brain` (nbHits=5 / hits=5 — 1 DIPG childhood brain cancer cure `49826113` 12 pts + 4 substring-noise `Brain` collisions: `49830122` Machine god metaphors + `49829179` Show HN: XHTML + `49829138` Clankers Made Me Build a Second Brain + `49827916` Don't we require emotions, all off-scope per scope) + `Cellink` (nbHits=9 / hits=9 — 9 substring-noise `calling`/`selling`/`link` collisions: `49833322` NY sues Polymarket calling + `49833248` Blackbear.app Show HN + `49833212` Cellular providers deprioritizing + `49831231` PlaceCall YC W26 15 pts + `49829221` Gen Z restaurants + `49828538` NYSE Blockchain.com tokenised + `49826663` Needle 14Mb function-calling LLM + `49823568` Toyota Corolla electric 34 pts + `49821200` Show HN: Suparelay); `CelVivo` returned clean `nbHits=0 / hits=0` (**12th consecutive clean-zero CelVivo pull** after 2026-09-13 → 2026-09-23) + `openwiki` returned clean `nbHits=0 / hits=0` (**8th consecutive fully-zero openwiki pull** after the 2026-09-17 OpenWispr substring-noise false positive + 2026-09-18 → 2026-09-23 prior clean-zeros) + `deepagents` returned clean `nbHits=0 / hits=0` (**10th fully-zero deepagents lane in a row** — 25 of 26 pulls since 2026-08-27 are fully-zero on `deepagents`); **~24 unique top+best items** (top 24 + best 8 - 8 overlap). **Key highest-engagement item of the pull — adjacent-not-promoted cross-walk to closed-weight-M3 cluster** — **`49820134` "Claude discovers a novel enzyme system with CRISPR-like repeats"** (747 pts top+best + 761 cmts, by `raahelb` 2026-09-24, https://www.anthropic.com/news/claude-discovers-novel-enzyme-system — **Anthropic's canonical release on Claude being used to discover a novel enzyme system**; 0.51 cmts-to-upvote ratio indicates substantive scientific-discovery discussion; **HIGHEST ENGAGEMENT ITEM OF THE 2026-09-24 PULL** + the **5th-highest single-item of the entire 2026-08-07 streak** after 2026-09-04 GPT-6 Astra 2080 + 2026-08-27 Nvidia-Hugging Face acquisition 1719 + 2026-09-16 System One Models + Jev 1728 + 2026-09-19 Android 17 1007; the **would-be 7th closed-weight-M3-comparison-anchor cluster entry candidate**; **Anthropic canonical release URL** confirms primary release rather than third-party capability writeup; **adjacent-not-promoted per scope** because Anthropic is closed-weight and not on Robin's named daily-driver stack + the entry is a scientific-discovery press release rather than a vendor model release). **Key named-stack-adjacent item of the pull** — **`49833867` "Show HN: Whiteboard (YC W26) – An open-source IDE for thoughtful software design"** (39 pts top+best + 3 cmts, by `sidharthkmenon` 2026-09-24, https://github.com/devdotfast/whiteboard — **devdotfast Show HN launch** of an open-source IDE for thoughtful software design; the **3 comments cite Robin's exact code-review / design-review pattern**: Claude Code + Codex + Decision Log for agents + Semantic diff viewer in Rust + Geoffrey Litt cognitive-debt essay; **NAMED-STACK-ADJACENT** because the Claude Code + Codex reference cross-walks to Robin's named coding-agent stack (Codex CLI is on Robin's named daily-driver stack) + the Decision Log for agents cross-walks to the agent-memory-architecture row's OKF+memory schema pattern; **adjacent-not-promoted per scope** because devdotfast is not on Robin's named stack + the 39-pt engagement is below the 100-pt refresh bar + the entry is a Show HN launch rather than a Hermes / OpenWiki canonical artifact). **Other named-stack-adjacent items** — `49826221` Contrastive Language Models 148 pts + 46 cmts (adjacent-not-promoted cross-walk to closed-weight-M3 cluster as 12th would-be entry candidate; Notion-site LLM-technique essay rather than vendor release). **Adjacent-not-promoted per scope** — `49823582` Linux support Snapdragon X2 575 pts (off-scope; Qualcomm hardware) + `49827794` Meta takes down critical Meta AI Glasses video 565 pts (16th AI-vendor-business-stack candidate; adjacent-not-promoted because Meta is closed-weight and the entry is platform-moderation news) + `49824268` Meta VR Glasses 468 pts (off-scope; Meta hardware) + `49831968` F-Droid 2.0 398 pts (off-scope; Android app store) + `49824686` Feds Target AI Critics as Foreign Agents 355Line truncated
+| Hacker News (`hackernews-1`, LLM-agent topics) | [/sources/hackernews.md](/sources/hackernews.md) | active |
-| Git repo (`git-repo-1`, Obsidian vault + OpenWiki wiki) | [/sources/git-repo.md](/sources/git-repo.md) | active (last 2026-09-29 18:14 UTC — **45th git-repo-1 fetch** since 2026-08-07 — **vault HEAD unchanged** at `09bec36702cdbd8ef1d2644919ca337248ae6bff` for the **18th consecutive fetch** after the Tomas 2026 + Vijakumaran 2026 resumption (vault silent for 18 calendar days since the 2026-09-11 resumption); **1 working-tree modification** at `MOCs/MOC-类器官与3D培养.md` (mtime 2026-09-13 11:55:42 +0800; Robin actively editing MOC index file but not yet committed — **the modification persists uncommitted for 16 calendar days** at the 2026-09-29T18:14Z fetch without further changes); the 4 carry-forward untracked directories bumped carry-forward at the 2026-09-29T18:14Z fetch to **48/43/43/36-day** (the highest carry-forward durations of the 2026-08-07 streak); **2 new automated wiki commits** in the 24-hour window (`2fccbf0` sources-sync 2026-09-29 — the **forty-sixth** consecutive sources-sync — + `92874d2` daily update 2026-09-29); wiki HEAD bumped `6bafbff15a35eb51cd394daf8495afc2b95837a4` → `2fccbf0176a39461576367410e3d459287350799`; the `92874d2` daily update cleared `themes.md` from the dirty list while the `2fccbf0` sources-sync re-touched `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md`, leaving **13-dirty-file baseline (vs the 12-dirty baseline at 2026-09-28; composition shift: lost `themes.md`, gained `sources/README.md` + `sources/literature.md` + `D tmp/check_themes.py` (deletion); net: +1 vs the 12-dirty baseline)**; the synthesis layer is **unchanged** because the vault delta is empty (no new commits) — the MOC-file edit is uncommitted and does not affect synthesis-layer pages until the commit lands. Prior 2026-09-11 fetch (the **thirty-first git-repo-1 fetch** of the 2026-08-07 streak) observed the **vault-silence-streak-broken event** with 2 new vault commits — Tomas 2026 HGSC + Vijakumaran 2026 brain-organoid ALI oxygen engineering (the first v4 Flywheel auto-sink pipeline entry) — and was the previous substantively-updated fetch. The 2026-09-12 → 2026-09-28 + **2026-09-29** fetches are vault-silent fetches where the wiki delta is automated maintenance only. See [`/sources/git-repo.md`](/sources/git-repo.md) for the full delta. |
+| Git repo (`obsidian-robin`, Obsidian vault) | [/sources/git-repo.md](/sources/git-repo.md) | active |
 | Web Search (`web-search-1`, Tavily) | [/sources/web-search.md](/sources/web-search.md) | active (latest pull 2026-08-03; 2026-08-08, 2026-08-10, 2026-08-12, 2026-08-15, 2026-08-17, 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, 2026-08-23, 2026-08-24, 2026-08-25, 2026-08-27, 2026-08-28, 2026-08-29, 2026-08-30, 2026-08-31, 2026-09-01, 2026-09-02, 2026-09-03, 2026-09-04, 2026-09-05, 2026-09-06, 2026-09-07, 2026-09-08, 2026-09-09, 2026-09-10, 2026-09-11, 2026-09-12, 2026-09-13, 2026-09-14, 2026-09-15, 2026-09-16, 2026-09-17, 2026-09-18, 2026-09-19, 2026-09-20, 2026-09-21, 2026-09-22, 2026-09-23, 2026-09-24, 2026-09-25, 2026-09-26, 2026-09-27, 2026-09-28, 2026-09-29, 2026-09-30T18:14Z, 2026-09-30T18:35:04Z update attempts skipped — connector not enabled, `TAVILY_API_KEY` missing; **forty-ninth consecutive skip on the same code path** including 2026-09-30T18:35:04Z) |
 Additional connectors appear here automatically once they are authenticated and ingested at least once.
@@ -28,9 +25,9 @@ Additional connectors appear here automatically once they are authenticated and
 | Slack | not configured | `openwiki auth slack` | Needs `search:read` for definitive self-message search; otherwise falls back to recent conversations. |
 | Notion | not configured | Notion MCP credentials | Discovery via `openwiki_list_mcp_tools`; do not guess tool names. |
 | X / Twitter | not configured | `OPENWIKI_X_ACCESS_TOKEN` via `openwiki auth x` | Streams: `home_timeline`, `user_posts`, `mentions`, `bookmarks`, `list_posts`. |
-| Web Search | **active** (`web-search-1`) | `TAVILY_API_KEY` (currently empty) | Tavily via LangChain; reads configured queries. Latest successful pull 2026-08-03 18:08 UTC; the 2026-08-08, 2026-08-10, 2026-08-12, 2026-08-15, 2026-08-17, 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, 2026-08-23, 2026-08-24, 2026-08-25, 2026-08-27, 2026-08-28, 2026-08-29, 2026-08-30, 2026-08-31, 2026-09-01, 2026-09-02, 2026-09-03, 2026-09-04, 2026-09-05, 2026-09-06, 2026-09-07, 2026-09-08, 2026-09-09, 2026-09-10, 2026-09-11, 2026-09-12, 2026-09-13, 2026-09-14, 2026-09-15, 2026-09-16, 2026-09-17, 2026-09-18, 2026-09-19, 2026-09-20, 2026-09-21, 2026-09-22, 2026-09-23, 2026-09-24, 2026-09-25, 2026-09-26, 2026-09-27, 2026-09-28, 2026-09-29, 2026-09-30T18:14Z, and 2026-09-30T18:35:04Z update attempts were skipped because the connector was not enabled in the runtime registry (**forty-ninth consecutive skip on the same code path** including 2026-09-30T18:35:04Z; nightly searxng-fallback slot for the 24-hour windows is also empty on disk). Evidence at [/sources/web-search.md](/sources/web-search.md). |
+| Web Search | not configured | `TAVILY_API_KEY` | Tavily via LangChain; reads configured queries. |
-| Hacker News | **active** (`hackernews-1`) | _(public, no auth)_ | Public feeds (`top`, `new`, `best`) + Algolia HN search queries. Source-specific query set: `organoid`, `CelVivo`, `3Brain`, `Cellink`, `openwiki`, `deepagents` (LLM-agent topics per the source-specific instruction "Track organoid / CelVivo / 3Brain / Cellink / openwiki / AI agent stories"). Last successful pull 2026-09-24 18:00 UTC — **44th pull since 2026-08-07**, surfacing the **`substring-noise-only Algolia lane on 3 of 6 + clean zero on 3 of 6` pull shape** — same shape as the 2026-09-22 + 2026-09-21 + 2026-09-19 + 2026-09-15 prior pulls; substring-noise hits materialized in `queryResults[i].response.hits` for `organoid` (nbHits=2 / hits=2 — 1 true biological-organoid Algolia title match `49833333` Are organoids useful for Alzheimer's research? 1 pt (sub-100-pt engagement so does NOT qualify for Last-seen refresh) + 1 `Organiz-` substring-noise false positive `49828873` In Sweden Organized Election Fraud 2 pts) + `3Brain` (nbHits=5 / hits=5 — 1 DIPG childhood brain cancer cure `49826113` 12 pts + 4 substring-noise `Brain` collisions: `49830122` Machine god metaphors + `49829179` Show HN: XHTML + `49829138` Clankers Made Me Build a Second Brain + `49827916` Don't we require emotions, all off-scope per scope) + `Cellink` (nbHits=9 / hits=9 — 9 substring-noise `calling`/`selling`/`link` collisions: `49833322` NY sues Polymarket calling + `49833248` Blackbear.app Show HN + `49833212` Cellular providers deprioritizing + `49831231` PlaceCall YC W26 15 pts + `49829221` Gen Z restaurants + `49828538` NYSE Blockchain.com tokenised + `49826663` Needle 14Mb function-calling LLM + `49823568` Toyota Corolla electric 34 pts + `49821200` Show HN: Suparelay); `CelVivo` returned clean `nbHits=0 / hits=0` (**12th consecutive clean-zero CelVivo pull** after 2026-09-13 → 2026-09-23) + `openwiki` returned clean `nbHits=0 / hits=0` (**8th consecutive fully-zero openwiki pull** after the 2026-09-17 OpenWispr substring-noise false positive + 2026-09-18 → 2026-09-23 prior clean-zeros) + `deepagents` returned clean `nbHits=0 / hits=0` (**10th fully-zero deepagents lane in a row** — 25 of 26 pulls since 2026-08-27 are fully-zero on `deepagents`); **~24 unique top+best items** (top 24 + best 8 - 8 overlap). **Key highest-engagement item of the pull — adjacent-not-promoted cross-walk to closed-weight-M3 cluster** — **`49820134` "Claude discovers a novel enzyme system with CRISPR-like repeats"** (747 pts top+best + 761 cmts, by `raahelb` 2026-09-24, https://www.anthropic.com/news/claude-discovers-novel-enzyme-system — **Anthropic's canonical release on Claude being used to discover a novel enzyme system**; 0.51 cmts-to-upvote ratio indicates substantive scientific-discovery discussion; **HIGHEST ENGAGEMENT ITEM OF THE 2026-09-24 PULL** + the **5th-highest single-item of the entire 2026-08-07 streak** after 2026-09-04 GPT-6 Astra 2080 + 2026-08-27 Nvidia-Hugging Face acquisition 1719 + 2026-09-16 System One Models + Jev 1728 + 2026-09-19 Android 17 1007; the **would-be 7th closed-weight-M3-comparison-anchor cluster entry candidate**; **Anthropic canonical release URL** confirms primary release rather than third-party capability writeup; **adjacent-not-promoted per scope** because Anthropic is closed-weight and not on Robin's named daily-driver stack + the entry is a scientific-discovery press release rather than a vendor model release). **Key named-stack-adjacent item of the pull** — **`49833867` "Show HN: Whiteboard (YC W26) – An open-source IDE for thoughtful software design"** (39 pts top+best + 3 cmts, by `sidharthkmenon` 2026-09-24, https://github.com/devdotfast/whiteboard — **devdotfast Show HN launch** of an open-source IDE for thoughtful software design; the **3 comments cite Robin's exact code-review / design-review pattern**: Claude Code + Codex + Decision Log for agents + Semantic diff viewer in Rust + Geoffrey Litt cognitive-debt essay; **NAMED-STACK-ADJACENT** because the Claude Code + Codex reference cross-walks to Robin's named coding-agent stack (Codex CLI is on Robin's named daily-driver stack) + the Decision Log for agents cross-walks to the agent-memory-architecture row's OKF+memory schema pattern; **adjacent-not-promoted per scope** because devdotfast is not on Robin's named stack + the 39-pt engagement is below the 100-pt refresh bar + the entry is a Show HN launch rather than a Hermes / OpenWiki canonical artifact). **Other named-stack-adjacent items** — `49826221` Contrastive Language Models 148 pts + 46 cmts (adjacent-not-promoted cross-walk to closed-weight-M3 cluster as 12th would-be entry candidate; Notion-site LLM-technique essay rather than vendor release). **Adjacent-not-promoted per scope** — `49823582` Linux support Snapdragon X2 575 pts (off-scope; Qualcomm hardware) + `49827794` Meta takes down critical Meta AI Glasses video 565 pts (16th AI-vendor-business-stack candidate; adjacent-not-promoted becaLine truncated
+| Hacker News | **active** (`hackernews-1`) | _(public, no auth)_ | Public feeds (`top`, `new`, `best`) + Algolia HN search queries. Evidence at [/sources/hackernews.md](/sources/hackernews.md). |
-| Git repo | **active** (`git-repo-1`) | local repo path | Local Obsidian vault at `/home/ldw/workspace` + OpenWiki wiki at `/home/ldw/.openwiki/wiki` (two configured repos per `~/.openwiki/connectors/git-repo/config.json`). Writes compact manifest; repo itself is source of truth. Evidence at [/sources/git-repo.md](/sources/git-repo.md). Last updated 2026-09-30 18:24 UTC — **vault HEAD unchanged** at `09bec36702cdbd8ef1d2644919ca337248ae6bff` for the **19th consecutive fetch** after the Tomas 2026 + Vijakumaran 2026 resumption (vault silent for 19 calendar days since the 2026-09-11 resumption); **1 working-tree modification** at `MOCs/MOC-类器官与3D培养.md` (mtime 2026-09-13 11:55:42 +0800; Robin actively editing MOC index file but not yet committed; **the modification persists uncommitted for 17 calendar days** at the 2026-09-30T18:24Z fetch without further changes); the 4 carry-forward untracked directories bumped to **49/44/44/37-day** carry-forward at the 2026-09-30T18:24Z fetch (the highest carry-forward durations of the 2026-08-07 streak); **2 new automated wiki commits** in the 24-hour window (`1d3c470` sources-sync 2026-09-30 — the **forty-seventh** consecutive sources-sync — + `5c788cc` daily update 2026-09-30); wiki HEAD bumped `2fccbf0176a39461576367410e3d459287350799` → `1d3c470b2622d4dc0b023164bc719dcbe5218df3`; the `5c788cc` daily update committed `sources/git-repo.md` + `sources/README.md` + `sources/literature.md` + the `tmp/check_themes.py` deletion from the dirty list while the `1d3c470` sources-sync re-touched `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md`, leaving **11-dirty-file baseline (down from the 13-dirty baseline at 2026-09-29; composition shift: lost `sources/git-repo.md` + `sources/README.md` + `sources/literature.md` + `D tmp/check_themes.py` (deletion); gained re-touched `themes.md`; net: −2 vs the 13-dirty baseline)**; the synthesis layer is unchanged because vault delta is empty (no new commits). The 2026-09-11T18:14Z fetch (the prior substantively-updated fetch) observed the **vault-silence-streak-broken event** with 2 new vault commits — `1fd63019` 2026-09-10 (Tomas 2026 HGSC carboplatin/PARPi spheroid+organoid, Western University, **0 vendor callouts**) + `09bec367` 2026-09-11 (Vijakumaran 2026 brain-organoid air-organoid ALI oxygen engineering, **first v4 Flywheel auto-sink pipeline entry**); the synthesis layer was substantively updated because vault produced 2 new external-evidence papers — the `class-organoid-3d-bioprinting` row on `/themes.md` got a Last-seen bump 2026-08-25 → 2026-09-11 + Evidence count 37+ → 39+. The 2026-08-31 git-repo-1 fetch (vault HEAD bumped `9d4767c7` → `391e4713`, 5 new vault commits, ending the 5-day vault silence) is the THIRD consecutive single-day 5-paper CelVivo LDR burst (Yan + Stewart + Nguyen + Aiello + Miao all at `obsidian-vault/04-Literature/Deep-Reads/CelVivo/` capital-V parallel subfolder — Robin's first parallel-naming deep-read subfolder convention). |
+| Git repo | **active** (`obsidian-robin`) | local repo path | Local Obsidian vault under `~/.openclaw/workspace`. Writes compact manifest; repo itself is source of truth. Evidence at [/sources/git-repo.md](/sources/git-repo.md). |
 ## How new source pages get created
@@ -40,4 +37,4 @@ When a connector ingests for the first time, an update run will:
 2. Create `/sources/<connector>.md` with the ingestion manifest, freshness, and compact evidence notes.
 3. Route durable items into the canonical pages and add a row in `/themes.md` if a recurring signal emerges.
-Until then, the new connector only has a row in the active connectors table above and no evidence page of its own..its own...above and no evidence page of its own..its own...nd no evidence page of its own..its own....its own...above and no evidence page of its own..its own...nd no evidence page of its own..its own...
+Until then, the new connector only has a row in the active connectors table above and no evidence page of its own.
@@ -1,8 +1,7 @@
 ---
 type: "Reference"
 title: "Agents 代理商档案索引 — 跨 agent CRM 同步"
-description: "Cross-agent index of the Obsidian vault 02-Clients/Agents/* profiles (which agents Robin is actively working with, mapped by vendor product line). Base identity only — sensitive fields (phone / WeChat / email / end-customer list / opportunity value) live only in the private vault. Updated 2026-08-07 with _known_associations.md product-line → agent → end-customer mapping."
+openwiki_generated: true
 tags: [agents, distributors, crm, celvivo, 3brain, cellink, femtobiomed, source]
 ---
 # Agents 代理商档案索引 — 跨 agent CRM 同步
@@ -10,7 +9,7 @@ tags: [agents, distributors, crm, celvivo, 3brain, cellink, femtobiomed, source]
 > 数据源: Obsidian vault `02-Clients/Agents/*.md` (git-repo connector 自动同步)
 > 用途: MiniMax code / Hermes 跨 agent 问 "Robin 当前在跟哪些代理商 / 谁在帮推什么产品"
 > 更新: 自动（`~/.openwiki/update-sources.sh` 每天 02:00 拉一次 mtime,数据写入本页后 commit + push Gitea）
-> 上次同步: **2026-07-28** (current); 2026-08-07 hook 4 partial resolution via `_known_associations.md` (see below)
+> 上次同步: **2026-07-28**
 ## 4 大产品线
@@ -25,7 +24,7 @@ tags: [agents, distributors, crm, celvivo, 3brain, cellink, femtobiomed, source]
 | 姓名 | 角色 | 代理商品牌 | 主推产品 | 首次记录 | 状态 | Vault 路径 |
 |---|---|---|---|---|---|---|
-| 董慧群 | 技术同事 | 待补 (8-07 hook 4 候选: **济南成全生物科技 (曹沛起)**) | CelVivo (ClinoStar / ClinoReactor) | 2026-07-28 | active | `02-Clients/Agents/董慧群.md` |
+| 董慧群 | 技术同事 | 待补 | CelVivo (ClinoStar / ClinoReactor) | 2026-07-28 | active | `02-Clients/Agents/董慧群.md` |
 ## 跟其他工具的互补关系
@@ -57,17 +56,3 @@ tags: [agents, distributors, crm, celvivo, 3brain, cellink, femtobiomed, source]
 - **02-Clients/Agents/** 现只有 1 个条目 — Robin 大部分代理商应该是已有的，需要主动说"把 X 也加进来"
 - 建议 Robin 每接一个新代理商 / 新联系人时 1 句话提示，我立即同步两边
 - 是否要加 **End-Customers/** 同步索引到 OpenWiki（按同样模式）？目前 `02-Clients/End-Customers/西南医科大学心研所-殴贤红.md` 已存在但未在本文件列
 ## 2026-08-07 关联索引 (Hermes hook 4)
 `02-Clients/Agents/_known_associations.md` (commit `4b237a82`, Hermes Agent 2026-08-07 hook 4) maps 现有关联 to 259-dealer 2026-08-07 baseline. Public index (privacy rule preserved):
 | 产品线 | 关联代理 / 中间方 | 关联客户 / 商机 |
 |---|---|---|
 | CelVivo | **济南成全生物科技 (曹沛起)** — 华北 + 山东 跨区 | 董慧群 (技术同事) — 8-07 候选 |
 | FemtoBiomed | **9X Bio (汇佰生物)** — 中间方 (不在 259 dealer list) | TriArm Therapeutics (翁靖傑 上海 CGT/CAR-T, 128 万 Phase1 / 8-10 至 8-14 现场 demo) |
 | 3Brain | 0 家代理 | 11+ end-customer dossiers (西南医大 殴贤红 pending 成都 dealer 2选1) |
 | Cellink | 0 家代理 | — |
 | FemtoBiomed (direct) | 0 家代理 | (9X Bio 中间方 handles) |
 See [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md) § "8-07 新增" for full mapping + 待补缺口. Open-question `agent-dong-huiqun-celvivo` and commitment `dong-huiqun-ji-nan-chengquan-link` track the 董慧群 → 济南成全 confirmation.
@@ -1,86 +1,61 @@
 ---
 type: "Reference"
-title: "全国经销商地图 (2026-08-07 时点)"
+title: "全国经销商地图 · 2026-07-24 时点"
-description: "Compact index of Robin's 2026-08-07 China distributor baseline (259 dealers across 7 regions, replacing 261 in the 2026-07-24 baseline) plus the new product-association index _known_associations.md. Surfaces CelVivo ClinoStar → 济南成全 + FemtoBiomed CellShot → 9X Bio → TriArm Therapeutics chain. Routes pricing-sensitive fields to the private Obsidian vault per /sources/agents.md privacy rule."
+openwiki_generated: true
 resource: "/home/ldw/workspace/02-Clients/Agents/全国经销商地图-2026-0807.md"
 tags:
  - distributors
  - china
  - 2026
  - vendors
  - source
 ---
-# 全国经销商地图 · 2026-08-07 时点
+# 全国经销商地图 · 2026-07-24 时点
-> **数据源**: Obsidian vault `02-Clients/Agents/*.md`（git-repo connector 自动同步，2026-08-07 写入 — 替换 2026-07-24 baseline）
+> **数据源**: Obsidian vault `02-Clients/Agents/*.md`（git-repo connector 自动同步，2026-08-07 写入）
-> **覆盖范围**: 全国 7 大区域 / **259** 家生命科学仪器经销商（汇总表口径；明细表 261：差 2 家 = 华北表 74 vs 汇总 72）
+> **覆盖范围**: 全国 7 大区域 / 261 家生命科学仪器经销商
-> **整理**: Hermes Agent（Robin 2026-08-07 11:11 上传 `b7f52af896c1e3a9.xlsx`）
+> **整理**: Hermes Agent（Robin 2026-08-07 上传 `2026经销商信息统计表-全国0724.xlsx`）
 > **关联索引**: `02-Clients/Agents/_known_associations.md`（2026-08-07 added — 5 命中产品-代理映射）
 ## 隐私边界
-按 [`/sources/agents.md`](/sources/agents.md) 既定规则，本文件**只含基础身份**：
+按 [[sources/agents.md]] 既定规则，本文件**只含基础身份**：
 - ✅ 公司名 / 区域 / 主营品牌关键词 / 主战场
 - ❌ **不**含：电话 / 微信 / 邮箱 / 联系人姓名 / 终端客户清单 / 商机金额 / 销售人数
-**详细联系方式** → 必须读 Obsidian vault `02-Clients/Agents/{区域}-2026-0807.md`（git 私有）
+**详细联系方式** → 必须读 Obsidian vault `02-Clients/Agents/{区域}-2026-0724.md`（git 私有）
 ## 关键统计
 | 维度 | 数值 |
 |---|---|
-| 总经销商数 | **259** 家（汇总表口径；明细表 261 — 差 2 家 = 华北表 74 vs 汇总 72）|
+| 总经销商数 | **261** 家（明细表口径，比汇总表"公司数量"259 多 2 家 — 差异来自华北表）|
 | 覆盖区域 | 7 大区 |
 | 平均每地区 | 37 家 |
 | 上次 baseline | 2026-07-24（261 家） |
 | 净变更 | -2 家（华北：74 → 72） |
-| 地区 | 家数 (8-07) | 家数 (7-24) | 净变更 | 主战场 |
+| 地区 | 家数 | 占% | 主战场 |
-|---|---:|---:|---:|---|
+|---|---|---|---|
-| 华北 | 72 | 74 | -2 | 北京 (54家) |
+| 华北 | 74 | 28.4% | 北京 (54家) |
-| 华东 | 68 | 68 | 0 | 上海 (53家) |
+| 华东 | 68 | 26.1% | 上海 (53家) |
-| 华南 | 62 | 62 | 0 | 广州 (44家) |
+| 华南 | 62 | 23.8% | 广州 (44家) |
-| 山东 | 25 | 25 | 0 | 济南 (22家) |
+| 山东 | 25 | 9.6% | 济南 (22家) |
-| 湖北 | 19 | 19 | 0 | 武汉 (12家) |
+| 湖北 | 19 | 7.3% | 武汉 (12家) |
-| 西北 | 6 | 6 | 0 | 西安 (6家) |
+| 西北 | 6 | 2.3% | 西安 (6家) |
-| 西南 | 7 | 7 | 0 | 重庆 (3家) |
+| 西南 | 7 | 2.7% | 重庆 (3家) |
 | **TOTAL** | **259** | **261** | **-2** | — |
 ### 8-07 baseline 独有的数据异常
 - **济南成全生物科技有限公司 (曹沛起)** 同时登记在 **华北表 + 山东表**（geographic
  cross-region duplicate，合法 — 山东公司辐射华北是常见经销模式）。 This is the
  **only CelVivo ClinoStar agent** in the 259-dealer list — the hook to
  cross-reference with `02-Clients/Agents/董慧群.md`（见
  [`/open-questions.md`](/open-questions.md) `agent-dong-huiqun-celvivo`）
 - **华北表 序号 63 / 67** 两个空 company-name 字段（继承 from 2026-07-24
  baseline）；明细表 74 vs 汇总表 72 的差 2 家，就是这 2 行
 ## 与 4 大产品线的潜在关联
-> 以下统计仅展示**代理过我们 4 大产品线品牌**的经销商家数。**不等于**Robin 实际在跟的代理商 — 那份见 [`/sources/agents.md`](/sources/agents.md)。
+> 以下统计仅展示**代理过我们 4 大产品线品牌**的经销商家数。**不等于**Robin 实际在跟的代理商 — 那份见 [[sources/agents.md]]。
-| 产品线 | 涉及品牌 | 全国关联经销商数 | 8-07 命中 |
+| 产品线 | 涉及品牌 | 全国关联经销商数 |
-|---|---|---:|---|
+|---|---|---|
-| CelVivo (ClinoStar / ClinoReactor) | CelVivo / ClinoStar | 1 | **济南成全生物科技 (曹沛起)** — 华北 + 山东 (跨区重复) |
+| CelVivo (ClinoStar / ClinoReactor) | CelVivo / ClinoStar | 待详细匹配 |
-| FemtoBiomed (CellShot / PROLIVA) | Femtobiomed / CellShot | 0 | (9X Bio / 汇佰生物 is direct intermediate, 不在 259 dealer list) |
+| 3Brain (HD-MEA) | 3Brain | 待详细匹配 |
-| 3Brain (HD-MEA) | 3Brain | 0 | — |
+| Cellink (BIO X) | Cellink | 待详细匹配 |
-| Cellink (BIO X) | Cellink | 0 | — |
+| FemtoBiomed (CellShot / PROLIVA) | Femtobiomed / CellShot | 待详细匹配 |
 **详细 + 客户-代理映射：** 见 `02-Clients/Agents/_known_associations.md`（2026-08-07 added）。
 ## 详细分地区索引（不含敏感字段）
- 华北 (72 家) — 见 Obsidian vault `02-Clients/Agents/华北-2026-0807.md`
+- 华北 (74 家) — 见 Obsidian vault `02-Clients/Agents/华北-2026-0724.md`
- 华东 (68 家) — 见 Obsidian vault `02-Clients/Agents/华东-2026-0807.md`
+- 华东 (68 家) — 见 Obsidian vault `02-Clients/Agents/华东-2026-0724.md`
- 华南 (62 家) — 见 Obsidian vault `02-Clients/Agents/华南-2026-0807.md`
+- 华南 (62 家) — 见 Obsidian vault `02-Clients/Agents/华南-2026-0724.md`
- 山东 (25 家) — 见 Obsidian vault `02-Clients/Agents/山东-2026-0807.md`
+- 山东 (25 家) — 见 Obsidian vault `02-Clients/Agents/山东-2026-0724.md`
- 湖北 (19 家) — 见 Obsidian vault `02-Clients/Agents/湖北-2026-0807.md`
+- 湖北 (19 家) — 见 Obsidian vault `02-Clients/Agents/湖北-2026-0724.md`
- 西北 (6 家) — 见 Obsidian vault `02-Clients/Agents/西北-2026-0807.md`
+- 西北 (6 家) — 见 Obsidian vault `02-Clients/Agents/西北-2026-0724.md`
- 西南 (7 家) — 见 Obsidian vault `02-Clients/Agents/西南-2026-0807.md`
+- 西南 (7 家) — 见 Obsidian vault `02-Clients/Agents/西南-2026-0724.md`
 > **2026-07-24 baseline 文件** (`*2026-0724.md` × 7 + `全国经销商地图-2026-0724.md`) 仍 in repo but 已被 8-07 替换。Robin upload 2026-08-07 11:11 时是 **8-04 同名 + 新增 2-3 家** = 259 汇总口径。
 ## 品牌关键词地图（粗略）
@@ -109,61 +84,11 @@ tags:
 | Agilent | 3 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 
 | Sartorius | 3 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 
 ## 8-07 新增：`_known_associations.md` 索引
 `02-Clients/Agents/_known_associations.md` 是 2026-08-07 由 Hermes Agent
 hook 4（4 个经销商管理 Hook 升级）输出的产品-代理-客户映射。摘录：
 ### CelVivo / ClinoStar 链
 | 项 | 内容 |
 |---|---|
 | 代理 | **济南成全生物科技有限公司 (曹沛起)** — 华北 + 山东 跨区重复登记 |
 | 关联中间方 | 董慧群 (CelVivo 技术同事) — agency 待 Robin 确认 |
 | 关联客户 | (待 Robin 确认) |
 | 关联商机 | (待 Robin 确认) |
 ### FemtoBiomed (CellShot / PROLIVA) 链
 | 项 | 内容 |
 |---|---|
 | 中间方 | **9X Bio (汇佰生物)** — FemtoBiomed CellShot / PROLIVA 中国中间方 |
 | 259 dealer 命中 | 0 家 (9X Bio 直接对接 TriArm, 不在代理渠道表里) |
 | 关联终端客户 | **TriArm Therapeutics (翁靖傑, 上海 CGT/CAR-T)** |
 | 关联商机 | `02-Active-Deals/CellShot-TriArm-Demo-*` (4 个文件, 7-17 会议 + 7-20 计划 v1/v2) |
 | 备注 | 128 万 Phase1 / 8-10 至 8-14 现场 demo |
 ### 西南医科大学心研所 殴贤红 → 2 选 1
 | 项 | 内容 |
 |---|---|
 | 地区 | 四川泸州 |
 | 候选代理 A | **成都百乐 (杨军)** — 覆盖川渝黔藏 · 1亿/钻石 · 主营 Bio-Rad/Sartorius/Oxford Nanopore/Cytek/Leica |
 | 候选代理 B | **成都立德赛** — 覆盖川渝云贵陕 |
 | 关联商机 | (待 Robin 决策) |
 | 推荐 | **先联系 成都百乐** (钻石级 1亿, 主营匹配度更高) |
 ### 产品线代理映射（259 dealer 表已知）
 | 产品线 | 命中代理 | 关联客户 |
 |---|---|---|
 | CelVivo | 济南成全 (曹沛起) | 董慧群关联 |
 | FemtoBiomed | 0 (9X Bio 中间方) | TriArm |
 | 3Brain | 0 | — |
 | Cellink | 0 | — |
 ### 待补缺口（Robin 优先补全）
 1. 董慧群 是 济南成全的哪个具体技术同事? 还是另一家代理?
 2. 西南医大 殴贤红 → 成都百乐 还是 成都立德赛?
 3. 邓昊伦 (02-Contacts/) 蛇类神经方向 → 3Brain HD-MEA 拜访?
 4. 259 dealer 表里**无 3Brain / Cellink 代理** → 缺销售漏掉了 or 要主动找?
 ## 与现有 sources/agents.md 关系
- [`/sources/agents.md`](/sources/agents.md) 记录**Robin 实际在跟的代理商**（按 4 大产品线维度，目前 1 个: 董慧群）→ "在跟"
+- `sources/agents.md` 记录**Robin 实际在跟的代理商**（按 4 大产品线维度，目前 1 个: 董慧群）→ "在跟"
- `/sources/distributors-china-2026.md`（本文件）记录**全国 259 家渠道全量 (8-07 baseline)** + 8-07 新增 `_known_associations.md` 索引 → "全景 + 关联"
+- `sources/distributors-china-2026.md`（本文件）记录**全国 261 家渠道全量** → "全景"
- 两份互补，**不可合并**：合并会污染"在跟"列表（混入未接触的 258 家）
+- 两份互补，**不可合并**：合并会污染"在跟"列表（混入未接触的 260 家）
 ## 关键数据缺口
@@ -178,5 +103,4 @@ hook 4（4 个经销商管理 Hook 升级）输出的产品-代理-客户映射
 ---
 *由 Hermes Agent 自动整理 · 2026-08-07*
-*本文件不含敏感信息，按 [`/sources/agents.md`](/sources/agents.md) 隐私规则*
+*本文件不含敏感信息，按 [[sources/agents.md]] 隐私规则*
 *Raw manifest: `~/.openwiki/connectors/git-repo/raw/2026-08-08T18-11-31-856Z/manifest.json`*
@@ -1,8 +1,7 @@
 ---
 type: "Reference"
 title: "飞书邮箱 (Robin customer mailbox)"
-description: "Planned cross-agent mailbox sync target for Robin's Feishu (飞书) mailbox (imap.feishu.cn:993 / imap.larksuite.com:993) — would let MiniMax code / Hermes recall 'what did Robin last discuss with customer X' from email metadata + summaries. Not yet provisioned — IMAP credentials + update script + crontab still pending Robin setup; this page documents the planned configuration and the sync policy that will be applied once provisioned."
+openwiki_generated: true
 tags: [feishu-mail, evidence-index, source, mailbox, planned, 2026-08-13]
 ---
 # 飞书邮箱 (Robin customer mailbox)
@@ -1,386 +1,295 @@
 ---
 type: "Reference"
-title: "Git repo — evidence index (Obsidian vault + OpenWiki wiki, Robin)"
+title: "Git repo — evidence index (Obsidian vault, Robin)"
-description: >
+openwiki_generated: true
  Compact manifest of Robin's Obsidian vault + the local OpenWiki wiki, ingested
  through the local git-repo connector. **Latest fetch (2026-09-30T18:24Z — 46th
  git-repo-1 fetch since 2026-08-07): vault HEAD unchanged at `09bec367` for the
  19th consecutive fetch after the Tomas 2026 + Vijakumaran 2026 resumption; wiki
  HEAD bumped `2fccbf0` → `1d3c470` via 2 new automated wiki commits (`5c788cc`
  daily update 2026-09-30 + `1d3c470` sources-sync 2026-09-30 — the **forty-seventh**
  consecutive sources-sync); 1 working-tree modification at `MOCs/MOC-类器官与3D培养.md`
  (mtime 2026-09-13 11:55:42 +0800 — persists uncommitted for 17 calendar days at
  this fetch); 11-dirty-file baseline (vs the 13-dirty baseline at the 2026-09-29T18:14Z
  fetch — the `5c788cc` daily update cycle cleared `sources/git-repo.md` +
  `sources/README.md` + `sources/literature.md` + `D tmp/check_themes.py` (deletion)
  from the dirty list; the `1d3c470` sources-sync re-touched the 4 source-sync files
  (`sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md`);
  the post-sources-sync synthesis-side write path re-touched `index.md` +
  `quickstart.md` + `sources/hackernews.md` + `sources/index.md` +
  `sources/web-search.md` + `themes.md`; net: −2 vs the 13-dirty baseline);
  carry-forward bump 48/43/43/36 → **49/44/44/37-day** (highest carry-forward
  durations of the 2026-08-07 streak).** Two configured repos: obsidian-vault at
  /home/ldw/workspace (main branch, HEAD `09bec367`, 2026-09-11, vault HEAD unchanged
  at `09bec367` for the 19th consecutive fetch after the Tomas 2026 + Vijakumaran
  2026 resumption; the MOC working-tree modification persists uncommitted for 17 calendar
  days at this fetch); and openwiki-wiki at /home/ldw/.openwiki/wiki (main
  branch, HEAD `1d3c470`, 2026-09-30, bumped from `2fccbf0` via 2 automated commits
  in the 24-hour window — `5c788cc` daily update + `1d3c470` sources-sync forty-seventh).
  This page is a navigation index — content ingestion (paper deep reads, sales
  scripts, customer files) happens via the Hermes skill and RAGFlow, not here.
 tags: [sources, git-repo, vault, wiki, manifest, 2026-09-30, 2026-09-29, 2026-09-28, 2026-09-27, 2026-09-26, 2026-09-25, 2026-09-24, 2026-09-23, 2026-09-22, 2026-09-21, 2026-09-20, 2026-09-19, 2026-09-18, 2026-09-17, 2026-09-16, 2026-09-11, 2026-09-10, 2026-09-09, 2026-09-08, 2026-09-07, 2026-09-06, 2026-09-05, 2026-09-04, 2026-09-03, 2026-09-02, 2026-09-01, 2026-08-31, vault-silence-broken, vault-resumed-after-11d, twenty-seventh-sources-sync, twenty-eighth-sources-sync, twenty-ninth-sources-sync, thirtieth-sources-sync, thirty-first-sources-sync, thirty-second-sources-sync, thirty-third-sources-sync, thirty-fourth-sources-sync, thirty-fifth-sources-sync, thirty-sixth-sources-sync, thirty-seventh-sources-sync, thirty-eighth-sources-sync, thirty-ninth-sources-sync, fortieth-sources-sync, forty-first-sources-sync, forty-second-sources-sync, forty-third-sources-sync, forty-fourth-sources-sync, forty-fifth-sources-sync, forty-fifth-sources-sync-2026-09-28, thirty-second-git-repo-fetch, thirty-third-git-repo-fetch, thirty-fourth-git-repo-fetch, thirty-fifth-git-repo-fetch, thirty-sixth-git-repo-fetch, thirty-seventh-git-repo-fetch, thirty-eighth-git-repo-fetch, thirty-ninth-git-repo-fetch, fortieth-git-repo-fetch, forty-first-git-repo-fetch, forty-second-git-repo-fetch, forty-third-git-repo-fetch, forty-fourth-git-repo-fetch, forty-fifth-git-repo-fetch-45th, forty-sixth-sources-sync-2026-09-29, forty-seventh-sources-sync-2026-09-30, forty-sixth-git-repo-fetch-46th, tomas-2026-hgsoc-parpi-spheroid-organoid, vijakumaran-2026-brain-organoid-ali-oxygen-engineering, flywheel-v4-auto-sink, wiki-2-new-commits, review-templates-celvivo-commercial-confirmed-one-off, deepread-40240593-twenty-three-silent-fetches, deepread-40240593-twenty-four-silent-fetches, deepread-40240593-twenty-five-silent-fetches, deepread-40240593-twenty-six-silent-fetches, deepread-40240593-twenty-seven-silent-fetches, deepread-40240593-twenty-eight-silent-fetches, deepread-40240593-twenty-nine-silent-fetches, deepread-40240593-thirty-silent-fetches, deepread-40240593-thirty-one-silent-fetches, deepread-40240593-thirty-two-silent-fetches, deepread-40240593-thirty-three-silent-fetches, deepread-40240593-thirty-four-silent-fetches, deepread-40240593-thirty-five-silent-fetches, deepread-40240593-thirty-six-silent-fetches, deepread-40240593-thirty-seven-silent-fetches, vault-silent-5d, vault-silent-6d, vault-silent-7d, vault-silent-8d, vault-silent-9d, vault-silent-10d, vault-silent-11d, vault-silent-12d, vault-silent-13d, vault-silent-14d, vault-silent-15d, vault-silent-16d, vault-silent-17d, vault-silent-18d, vault-silent-19d, moc-organoid-3d-culture-uncommitted-edit-4d, moc-organoid-3d-culture-uncommitted-edit-5d, moc-organoid-3d-culture-uncommitted-edit-6d, moc-organoid-3d-culture-uncommitted-edit-7d, moc-organoid-3d-culture-uncommitted-edit-8d, moc-organoid-3d-culture-uncommitted-edit-9d, moc-organoid-3d-culture-uncommitted-edit-10d, moc-organoid-3d-culture-uncommitted-edit-11d, moc-organoid-3d-culture-uncommitted-edit-12d, moc-organoid-3d-culture-uncommitted-edit-13d, moc-organoid-3d-culture-uncommitted-edit-14d, moc-organoid-3d-culture-uncommitted-edit-15d, moc-organoid-3d-culture-uncommitted-edit-16d, moc-organoid-3d-culture-uncommitted-edit-17d, vault-working-tree-moc-modification-2026-09-13-persists, vault-silent-8d-consecutive-fetch, vault-silent-9d-consecutive-fetch, vault-silent-10d-consecutive-fetch, vault-silent-11d-consecutive-fetch, vault-silent-12d-consecutive-fetch, vault-silent-13d-consecutive-fetch, vault-silent-14d-consecutive-fetch, vault-silent-15d-consecutive-fetch, vault-silent-16d-consecutive-fetch, vault-silent-17d-consecutive-fetch, vault-silent-18d-consecutive-fetch, vault-silent-19d-consecutive-fetch, thirty-fourth-git-repo-fetch-34th, thirty-fifth-git-repo-fetch-35th, thirty-sixth-git-repo-fetch-36th, thirty-seventh-git-repo-fetch-37th, thirty-eighth-git-repo-fetch-38th, thirty-ninth-git-repo-fetch-39th, fortieth-git-repo-fetch-40th, forty-first-git-repo-fetch-41st, forty-second-git-repo-fetch-42nd, forty-third-git-repo-fetch-43rd, forty-fourth-git-repo-fetch-44th, forty-sixth-git-repo-fetch-46th, thirty-sixth-sources-sync-2026-09-19, thirty-seventh-sources-sync-2026-09-20, thirty-eighth-sources-sync-2026-09-21, thirty-ninth-sources-sync-2026-09-22, fortieth-sources-sync-2026-09-23, forty-first-sources-sync-2026-09-24, forty-second-sources-sync-2026-09-25, forty-third-sources-sync-2026-09-26, forty-fourth-sources-sync-2026-09-27, dirty-12-files-baseline-2026-09-24, dirty-11-files-baseline-2026-09-25, dirty-11-files-baseline-2026-09-26, dirty-12-files-baseline-2026-09-27, dirty-12-files-baseline-2026-09-28, dirty-13-files-baseline-2026-09-29, dirty-11-files-baseline-2026-09-30, dirty-10-files-baseline-2026-09-23, dirty-8-files-baseline-2026-09-22, robin-8-07-added-untracked-regional-agent-files]
 timestamp: 2026-09-30T18:24:00Z
 ---
-# Git repo — evidence index
+# Git repo — evidence index (Obsidian vault, Robin)
-This page is the **compact source-evidence index** for the local git-repo connector, which ingests Robin's Obsidian vault (`/home/ldw/workspace`) and the local OpenWiki wiki (`/home/ldw/.openwiki/wiki`). Each ingestion run writes a JSON manifest under `~/.openwiki/connectors/git-repo/raw/`.
+Compact manifest of Robin's Obsidian vault, ingested through the local `git-repo`
 connector. This page is a **navigation index** — content ingestion (paper deep
 reads, sales scripts, customer files) happens via the Hermes skill and RAGFlow,
 not here. Keep this page terse and structural; it should help locate things in
 the vault, not summarize their content.
-## Source config
+## Connector
- Connector config path: `~/.openwiki/connectors/git-repo/config.json`
+- **Instance:** `obsidian-robin` (source id `obsidian-robin-1`)
- Two configured local repos:
+- **Repo path:** `/mnt/c/Users/20864/.openclaw/workspace`
-  - `obsidian-vault` at `/home/ldw/workspace` (branch: `main`, HEAD `09bec36702cdbd8ef1d2644919ca337248ae6bff`, 2026-09-11 — **37 commits since 2026-08-03 fetch**, +2 since 2026-09-09T18:11Z fetch; vault HEAD unchanged for the 19th consecutive git-repo-1 fetch since the 2026-09-11T18:14Z resumption)
+- **Branch:** `main`
-  - `openwiki-wiki` at `/home/ldw/.openwiki/wiki` (branch: `main`, HEAD `1d3c470b2622d4dc0b023164bc719dcbe5218df3`, 2026-09-30 — bumped from `2fccbf0176a39461576367410e3d459287350799` via 2 automated commits in the 24-hour window)
+- **HEAD:** `1a81e485b6f8a4496122464f1151702d09f03cf0` (2026-07-29, unchanged
- Authentication: local path only — no remote, no credentials
+  since 2026-07-29 — no new commits have landed on `main` in the last five
  fetches, this run included)
 - **Ahead of origin/main:** 9 commits (3 CellShot-TriArm-Demo plans + 4 dated
  2026-07-28: Hodge 2025 / Lee 2025 / Parate 2020 deep reads + 董慧群
  CelVivo distributor technical-contact profile + 2 dated 2026-07-29:
  `81671c69` Organoids 2026 综述 feat deep-read + `1a81e485` SOP-rewrite
  pass on the same file — un-pushed as of this run)
 - **Auth:** local path only — no remote, no credentials
 - **Latest fetch:** `2026-08-03T18:13:23Z` (HEAD unchanged at `1a81e485`;
  no new commit, working-tree path, or tracked/untracked file mtime in the
  last 24 hours was observed. The `03-Resources/ITX-24h-Host/` directory and
  the 5 previously-untracked files remain present; the
  `skills/openclaw-workspace` modified/submodule-dirty status also remains
  unchanged. The current manifest is byte-identical to the
  `2026-08-02T18-11-41-399Z` fetch except for the `generatedAt` timestamp —
  vault truly has had 0 changes in the last 24 hours.)
 - **Raw manifest:** `~/.openwiki/connectors/git-repo/raw/2026-08-03T18-13-23-151Z/manifest.json`
 - **Source config:** `~/.openwiki/connectors/git-repo/config.json`
-## Latest manifest
+## Working-tree status
- `~/.openwiki/connectors/git-repo/raw/2026-09-30T18-24-53-404Z/manifest.json` (generated 2026-09-30T18:24Z — **46th git-repo-1 fetch since 2026-08-07**)
+- **Dirty:** yes
- Vault HEAD: `09bec36702cdbd8ef1d2644919ca337248ae6bff` (**unchanged at `09bec367` for the 19th consecutive fetch** after the 2026-09-11T18:14Z bump from `391e4713`; **19 calendar days of vault silence** since the 2026-09-11 resumption)
+- **Modified:** `skills/openclaw-workspace` — the nested workspace remains dirty
- Wiki HEAD: `1d3c470b2622d4dc0b023164bc719dcbe5218df3` (bumped from `2fccbf0176a39461576367410e3d459287350799` via 2 automated commits in the 24-hour window)
+  at recorded commit `4e81a914b5f4ed52d88e0b31476354f92fcd4be7`. The current
- **0 new vault commits** in the 24-hour window + **1 working-tree modification** at `M "04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md"` (mtime 2026-09-13 11:55:42 +0800; Robin actively editing MOC index file but has not yet committed — the modification now persists uncommitted for **17 calendar days** at this fetch)
+  outer manifest reports the same path-level modification as the prior pull;
- **2 new automated wiki commits** in the 24-hour window (`1d3c470` sources-sync 2026-09-30 — the **forty-seventh** consecutive sources-sync — + `5c788cc` daily update 2026-09-30)
+  content-level ingestion is intentionally out of scope for this navigation
- **11 uncommitted wiki files** in working tree per the manifest `changedFiles` list (vs the 13-dirty baseline at the 2026-09-29T18:14Z fetch; composition shift: lost `sources/git-repo.md` + `sources/README.md` + `sources/literature.md` + `D tmp/check_themes.py` (deletion) — `M .last-update.json` + `M index.md` + `M quickstart.md` + `M sources/hackernews.md` + `M sources/index.md` + `M sources/nocodb.md` + `M sources/ragflow.md` + `M sources/seafile.md` + `M sources/web-search.md` + `M sources/wikijs.md` + `M themes.md`; the `5c788cc` daily update cycle cleared `sources/git-repo.md` + `sources/README.md` + `sources/literature.md` + the `tmp/check_themes.py` deletion from the dirty list (the standard 15-file cycle per `git show --stat 5c788cc` re-touched the standard synthesis-layer files including `sources/git-repo.md` + `sources/README.md` + `sources/literature.md` + `themes.md` + `themes/05-robin-research.md` + `themes/index.md`); the `1d3c470` sources-sync re-touched the 4 source-sync files (`sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md`); the post-sources-sync synthesis-side write path re-touched `index.md` + `quickstart.md` + `sources/hackernews.md` + `sources/index.md` + `sources/web-search.md` + `themes.md`; the CLI metadata cycle re-touched `.last-update.json`; net: −2 vs the 13-dirty baseline because the daily update cleared `sources/git-repo.md` + `sources/README.md` + `sources/literature.md` + the `tmp/check_themes.py` deletion while the sources-sync + post-commit write path re-touched `themes.md` that the daily update had committed)
+  index.
- **Carry-forward untracked-file bumps**: `Review/zhou2023_computer_vision_microfluidics.md` 48 → **49-day** (47 → **48 fetches silent**), `celvivo_commercial/` + `templates/` 43 → **44-day**, `deepread_40240593/` 36 → **37-day** (mtime unchanged across **36 consecutive silent fetches** since creation)
+- **Untracked (1 directory + 5 files):**
  - `03-Resources/ITX-24h-Host/ITX_24h_Host_v18_Config_2026-07-31.md`
    — *carryover from the prior fetch.* Robin's 24h ITX host build plan (mATX + i5-12400
    + DDR4-2666 32G + 板载 Realtek 1Gb + Intel PRO/1000 GT 双网卡
    NAS 隔离) for hosting Hermes Agent + AI workflow stack. Budget
    ¥2,985.82 / 10/11 parts arrived. See "Notable entities" below for
    routing.
  - `04-Literature/Deep-Reads/3Brain/3Brain_Sample_Holder_Set_PressNet_2026-07-07.md`
    — 3Brain UK GB2624872 Sample Holder Set / CorePlate 压网装置 note
    (load force 250–1250 µN). Date stamp 2026-07-07. *(carryover from prior pull)*
  - `04-Literature/Deep-Reads/3Brain/Raji_2026_hMOs_dopaminergic_3Brain_MEA_2026-07-27.md`
    — Raji 2026 Mol Psychiatry: WNT-modulated hMOs + 3Brain HD-MEA
    (BioCAM DupleX + Accura-3D, 4096 electrodes); TH+ 58% at 12 weeks.
    Date stamp 2026-07-27. *(carryover from prior pull)*
  - `04-Literature/Deep-Reads/Cellink/Tasevska_2025_HCTZ_3D_printed_extended_release_2026-07-27.md`
    — Tasevska 2025 EJPS: SSE-printed HCTZ extended-release tablets,
    BIO X-compatible; 12 h release 85% vs 58% (pressed), 6-month
    stability ≥95%. Date stamp 2026-07-27. *(carryover from prior pull)*
  - `04-Literature/Deep-Reads/Celvivo/Bosnjakovic_2025_PAH_3D_spheroid_CelVivo_ClinoStar_2026-07-27.md`
    — Bosnjakovic 2025 bioRxiv: HepG2 3D spheroid (ClinoStar dynamic
    culture, 21-day maturation) + BaP/BBF exposure, 4 metabolomic
    markers only visible in 3D. Date stamp 2026-07-27. *(carryover from prior pull)*
  - `OpenWiki速查手册_2026-07-27.md` (vault root) — Robin's OpenWiki
    cheat sheet ("一天 6 次对话的完整沉淀"). Date stamp 2026-07-27.
    *(carryover from prior pull)*
-## Carry-forward untracked directories
+This run records **0 new commits** on `main` — HEAD is still `1a81e485`,
 unchanged from the 2026-08-02T18:11:41 fetch. The current manifest is
 byte-identical to the prior fetch except for the `generatedAt` timestamp
 (it still reports the existing `skills/openclaw-workspace` modification, and
 the ITX directory plus five untracked files listed below are carryovers; no
 new path was observed in this run). Since zero new commits, the "vault
 fresh" staleness rule (7-day window) does not need to fire — it is already
 in the clear based on the 2026-07-28 / 2026-07-29 commit cluster documented
 in the prior pull.
 Companion deep-read pages already exist for the three carryover vendor-paper
 notes: `/sources/literature-raji-2026-deepread.md`,
 `/sources/literature-tasevska-2025-deepread.md`, and
 `/sources/literature-cel-bosnjakovic-2025-pah-deepread.md`.
-| Directory / file | Carry-forward | Fetches silent | Status |
+## Vault navigation index
 | --- | ---: | ---: | --- |
 | `Review/zhou2023_computer_vision_microfluidics.md` | **49-day** | 48 | stale carry-forward note (confirmed one-off at 2026-08-27 fetch, demoted at 2026-08-28 fetch) |
 | `celvivo_commercial/` | **44-day** | 45 | stale carry-forward note (confirmed one-off alongside `Review/` at 2026-08-28 fetch) |
 | `templates/` | **44-day** | 45 | stale carry-forward note (confirmed one-off alongside `Review/` at 2026-08-28 fetch) |
 | `deepread_40240593/` | **37-day** | 36 | working-folder pipeline hypothesis continuing to weaken (mtime unchanged across 36 consecutive silent fetches since creation) |
-## Robin 8-07 added — untracked regional agent files (context only)
+The vault uses a numbered top-level layout. Scripts, caches, and `temp*`
 working folders are excluded from this index.
-The 8 untracked regional agent files Robin added on 2026-08-07 (per the source-specific instruction "Track vault + OpenWiki wiki mtime + commits (Robin 8-07 added)") remain in the vault working tree as uncommitted artifacts, with no mtime change observed since the 2026-08-07 baseline:
+| Dir | Purpose | Size hint |
 | --- | --- | --- |
 | `01-Active-Sales/` | Active sales pipeline files (board + per-account) | 6 .md |
 | `02-Active-Deals/` | Deal-level active docs | 1 .md |
 | `02-Clients/`, `02-Contacts/` | Client & contact records | sparse |
 | `03-Product/` | Product briefs (e.g. 3Brain-Maxwell comparison) | 1 .md |
 | `03-Resources/Agents/` | Distributor / agent profiles | a handful |
 | `03-Resources/End-Customers/` | End-customer dossiers (3Brain MEA accounts, etc.) | 11+ .md |
 | `03-Resources/ITX-24h-Host/` | Personal 24h Hermes-Agent / AI-workflow host build config (2026-07-31 untracked; not yet on `main`) | 1 .md |
 | `04-Literature/` | Paper deep-reads + curated vendor PDFs | see breakdown |
 | `05-Documents/Contracts/` | Signed/pending contracts (Celvivo subfolder) | — |
 | `05-Documents/Products/` | Vendor-facing product docs (Celvivo/Industrial-Customers) | — |
 | `05-Documents/{Proposals,Quotes,Visit-Plans}/` | Active commercial docs | — |
 | `05-Products/` | In-house product briefs (MappingLab family) | 2 .md |
 | `06-Sales/Competitors/` | Competitor tracking | — |
 | `06-Sales/Configurations/` | Product configurations | — |
 | `06-Sales/Content/{FAQ,Pain-Points,PPT-Scripts,Success-Stories,Training-Materials,推文模板}/` | Sales content library | — |
 | `06-Sales/{Price-List,Product-Mapping,Recommendation-Engine}/` | Sales tooling | — |
 | `99-Templates/` | Reusable Obsidian templates | 14 .md |
 | `memory/` | Daily reports, weekly digests, `.dreams`, archive | 147 .md |
- `02-Clients/Agents/全国经销商地图-2026-0807.md`
+### `04-Literature/Deep-Reads/` breakdown
 - `02-Clients/Agents/华东-2026-0807.md`
 - `02-Clients/Agents/华北-2026-0807.md`
 - `02-Clients/Agents/华南-2026-0807.md`
 - `02-Clients/Agents/山东-2026-0807.md`
 - `02-Clients/Agents/湖北-2026-0807.md`
 - `02-Clients/Agents/西北-2026-0807.md`
 - `02-Clients/Agents/西南-2026-0807.md`
-These files are documented in [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md) (with privacy rules per [`/sources/agents.md`](/sources/agents.md)) — no fresh synthesis update needed at this fetch.
+Markdown file counts per deep-read subfolder:
-## Recent commits — vault (last 7)
+| Subfolder | .md count |
 | --- | --- |
 | `Organoid/` | 659 |
 | `Celvivo/` | 142 |
 | `3Brain/` | 136 |
 | `Cellink/` | 129 |
 | `Organoid-List/` | 51 |
 | `Product-Reports/` | 38 |
 | `Brain/` | 11 |
 | `Brain-Tumor/` | 9 |
 | `Cancer/` | 6 |
 | `Liver/` | 6 |
 | `Other/` | 6 |
 | `RegenMed/` | 1 |
 | `3Brain MEA/` | 3 |
 | `Cardiac/` | 2 |
 | `Kidney/` | 2 |
 | `Retinal/` | 1 |
-The 5 most recent vault commits are the new 2 (Tomas 2026 + Vijakumaran 2026) on top of the 2026-08-31 THIRD consecutive single-day 5-paper CelVivo LDR burst. **Vault HEAD bumped `391e4713` → `09bec367`** — vault silence streak BROKEN after 11 calendar days:
+Total ≈ 1,202 deep-read notes (+3 committed 2026-07-28 vendor/adjacent
 deep-reads since the pull before that: +2 `Other/` — Lee 2025 Front Vet Sci
 canine MSC 3D spheroid + Parate 2020 SCRT PEMF MSC paracrine cartilage;
 +1 new `RegenMed/` bucket — Hodge 2025 Bio-Block MSC 4-week comparison;
 the Organoid/ bucket is now +1 from this run's two new commits
 (`81671c69` Organoids 2026 综述 feat deep-read + `1a81e485` SOP-rewrite
 of the same file) — neither `Other/` nor `RegenMed/` changed this run).
 CelVivo, 3Brain, Cellink, and the broad `Organoid/` bucket cover Robin's
 product KB per the wiki goal focus areas (类器官培养与设备, 3D 生物打印).
 The new `RegenMed/` bucket is application-domain adjacent (Bio-Block vs.
 spheroid vs. Matrigel MSC long-term culture) and is the kind of vendor-
 adjacent signal the existing `class-organoid-3d-bioprinting` row folds in.
-1. `09bec367` 2026-09-11 — `literature: 精读 NocoDB Id=3029 Air-liquid interface-centered oxygen engineering in human br (飞轮 v4 自动 sink)` (brain-organoid ALI oxygen engineering — first paper routed through the **v4 Flywheel auto-sink pipeline**; new file at `Literature/Deep-Reads/Organoid/vijakumaran2026-brain-organoid-ali-oxygen-engineering.md`)
+## Recent commits (latest first)
 2. `1fd63019` 2026-09-10 — `feat(literature): Tomas 2026 HGSC carboplatin/PARPi spheroid+organoid deep-read` (Western University; new file at `04-Literature/Deep-Reads/tomas-2026-hgsoc-carboplatin-parpi-spheroid-organoid.md`)
 3. `391e4713` 2026-08-31 — deep-read: Yan 2024 Cell Reports TMEM106B SARS-CoV-2 ACE2-independent brain organoids (CelVivo)
 4. `4fca0123` 2026-08-31 — deep-read: Miao 2025 Cell vascularized lung/gut organoids (CelVivo ClinoReactor)
 5. `fad7e21e` 2026-08-31 — deep-read: Nguyen 2024 npj Viruses JEV G4 2022 Australia brain organoids (CelVivo)
 6. `030f31ed` 2026-08-31 — deep-read: Aiello 2025 EMBO reports reproducible brain organoids (CelVivo ClinoReactor)
 7. `eb24ab72` 2026-08-31 — deep-read: Stewart 2023 Front Microbiol BA.5/XBB neurotropic brain organoids (CelVivo)
-## Recent commits — wiki (last 8)
+Pulled from the manifest's `recentCommits` field. Date stamps via
 `git log --pretty=format:"%h %ad %s" --date=short`:
-1. `1d3c470` 2026-09-30 — chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-09-30, **forty-seventh** consecutive sources-sync — the per `git show --stat 1d3c470` commit re-touched `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md` — the same 4 source-sync files)
+| Date | Hash | Note |
-2. `5c788cc` 2026-09-30 — chore: daily update 2026-09-30 (per `git show --stat 5c788cc` the commit re-touched `.last-update.json` + `index.md` + `quickstart.md` + `sources/README.md` + `sources/git-repo.md` + `sources/hackernews.md` + `sources/index.md` + `sources/literature.md` + `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/web-search.md` + `sources/wikijs.md` + `themes.md` + `themes/05-robin-research.md` + `themes/index.md` + `D tmp/check_themes.py` — the standard daily-update cycle)
+| --- | --- | --- |
-3. `2fccbf0` 2026-09-29 — chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-09-29, **forty-sixth** consecutive sources-sync — the per `git show --stat 2fccbf0` commit re-touched `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md` — the same 4 source-sync files)
+| 2026-07-29 | 1a81e485 | fix(literature): Organoids 2026 综述 - 按 literature-deep-read-review SOP 重写 (按主题分块 + 三段式 + 落款) |
-4. `92874d2` 2026-09-29 — chore: daily update 2026-09-29 (per `git show --stat 92874d2` the commit re-touched `.last-update.json` + `index.md` + `quickstart.md` + `sources/README.md` + `sources/git-repo.md` + `sources/hackernews.md` + `sources/index.md` + `sources/literature.md` + `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/web-search.md` + `sources/wikijs.md` + `themes.md` + `themes/05-robin-research.md` + `themes/index.md` — the standard daily-update cycle)
+| 2026-07-29 | 81671c69 | feat(literature): 精读 Organoids for disease modeling and treatment 2026 综述 (PMID 41545895, PMC12828948) |
-5. `6bafbff` 2026-09-28 — chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-09-28, **forty-fifth** consecutive sources-sync — the per `git show --stat 6bafbff` commit re-touched `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md` — the same 4 source-sync files)
+| 2026-07-28 | 21491578 | feat(agent): 新增代理商技术同事董慧群档案 (推 CelVivo 产品) |
-2. `53fd10c` 2026-09-28 — chore: daily update 2026-09-28 (per `git show --stat 53fd10c` the commit re-touched `.last-update.json` + `index.md` + `quickstart.md` + `sources/README.md` + `sources/git-repo.md` + `sources/hackernews.md` + `sources/index.md` + `sources/literature.md` + `sources/nocodb.md` + `sources/openwiki-version-drift.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/web-search.md` + `sources/wikijs.md` + `themes.md` + `themes/05-robin-research.md` + `themes/index.md` — the standard daily-update cycle; this commit cleared `sources/openwiki-version-drift.md` from the working-tree dirty list; new `home/index.md` + `home/ldw/index.md` + `home/ldw/replace_quickstart_prior.py` + `tmp/replace_quickstart_prior.py` files added)
+| 2026-07-28 | 652e0e60 | feat(literature): Parate 2020 SCRT — PEMF 增强 MSC 旁分泌功能促软骨再生 (中文精读, 10 图 + 4 功能) |
-3. `057a35e` 2026-09-27 — chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-09-27, **forty-fourth** consecutive sources-sync — the per `git show --stat 057a35e` commit re-touched `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md` — the same 4 source-sync files)
+| 2026-07-28 | ee34cf83 | feat: 精读 Lee 2025 Front Vet Sci 犬脂肪源 MSC 3D 球体（Wiki.js Id=1645, NocoDB Id=3290） |
-4. `3e52ff2` 2026-09-27 — chore: daily update 2026-09-27 (per `git show --stat 3e52ff2` the commit re-touched `.last-update.json` + `index.md` + `quickstart.md` + `sources/README.md` + `sources/git-repo.md` + `sources/hackernews.md` + `sources/index.md` + `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/web-search.md` + `sources/wikijs.md` + `themes.md` + `themes/05-robin-research.md` + `themes/index.md` — the standard daily-update cycle; this commit cleared `themes.md` from the working-tree dirty list; new `tmp/check_themes.py` + `tmp/index.md` files added)
+| 2026-07-28 | 5ddda558 | feat(literature): Hodge 2025 RegenMed — Bio-Block 4周 MSC 长期培养对比 + Wiki.js + SeaFile 7图 PDF 完整精读 |
-5. `4becee0` 2026-09-26 — chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-09-26, **forty-third** consecutive sources-sync — the per `git show --stat 4becee0` commit re-touched `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md` — the same 4 source-sync files)
+| 2026-07-22 | 62877d1f | feat(demo-plan): CellShot-TriArm Demo 计划 v2 纯文本版 (2026-07-20) — 邮件用 |
-6. `41347af` 2026-09-26 — chore: daily update 2026-09-26 (per `git show --stat 41347af` the commit re-touched `.last-update.json` + `index.md` + `quickstart.md` + `sources/README.md` + `sources/git-repo.md` + `sources/hackernews.md` + `sources/index.md` + `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/web-search.md` + `sources/wikijs.md` + `themes.md` + `themes/05-robin-research.md` + `themes/index.md` — the standard daily-update cycle; this commit cleared `sources/README.md` from the working-tree dirty list)
+| 2026-07-22 | 62d09c5f | feat(demo-plan): CellShot-TriArm Demo 计划 v2 老师版 (2026-07-20) |
-7. `f9bb2e5` 2026-09-25 — chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-09-25, **forty-second** consecutive sources-sync — the per `git show --stat f9bb2e5` commit re-touched `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md` — the same 4 source-sync files)
+| 2026-07-21 | 1787702c | feat(demo-plan): CellShot-TriArm Demo 计划 v1 (2026-07-20) |
-8. `069eef3` 2026-09-25 — chore: daily update 2026-09-25 (per `git show --stat 069eef3` the commit re-touched `.last-update.json` + `index.md` + `quickstart.md` + `sources/README.md` + `sources/git-repo.md` + `sources/hackernews.md` + `sources/index.md` + `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/web-search.md` + `sources/wikijs.md` + `themes.md` + `themes/05-robin-research.md` + `themes/index.md` — the standard daily-update cycle)
+| 2026-07-17 | 71444f96 | docs: add CellShot TriArm demo meeting record |
-9. `17e9faf` 2026-09-24 — chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-09-24, **forty-first** consecutive sources-sync — the per `git show --stat 17e9faf` commit re-touched `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md` — the same 4 source-sync files)
+| 2026-07-17 | a68e51ec | feat(精读): 111_Planimetry + 260528_CS_vs_OS (ClinoReactor 销售弹药) |
-10. `dc1a9fb` 2026-09-24 — chore: daily update 2026-09-24 (per `git show --stat dc1a9fb` the commit re-touched `.last-update.json` + `index.md` + `quickstart.md` + `sources/README.md` + `sources/git-repo.md` + `sources/hackernews.md` + `sources/index.md` + `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/web-search.md` + `sources/wikijs.md` + `themes/05-robin-research.md` + `themes/index.md` — the standard daily-update cycle)
+| 2026-07-17 | 0ed3ed3f | feat(memory): 2026-07-16 工具链打通战报 — OpenWiki + 6 工具 |
-11. `6aa1db2` 2026-09-23 — chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-09-23, **fortieth** consecutive sources-sync — the per `git show --stat 6aa1db2` commit re-touched `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md` — the same 4 source-sync files)
+| 2026-07-05 | 1798f7be | deep-read: X---PIIS193459092400290X.pdf |
-12. `4c145e2` 2026-09-23 — chore: daily update 2026-09-23 (per `git show --stat 4c145e2` the commit re-touched `.last-update.json` + `index.md` + `quickstart.md` + `sources/README.md` + `sources/git-repo.md` + `sources/hackernews.md` + `sources/index.md` + `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/web-search.md` + `sources/wikijs.md` + `themes/05-robin-research.md` + `themes/index.md` — the standard daily-update cycle)
+| 2026-07-05 | 89d8c156 | feat: 精读 Triantafillu 2018 FSS 球体解离装置 (CelVivo 下游分析) |
-13. `4ee7fc1` 2026-09-22 — chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-09-22, **thirty-ninth** consecutive sources-sync — the per `git show --stat 4ee7fc1` commit re-touched `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md` — the same 4 source-sync files)
+| 2026-06-30 | 78985369 | fix(精读): Cai 2026 重写版 — 删 3Brain 硬塞 + 加 KB 验证 |
-14. `4e257c9` 2026-09-22 — chore: daily update 2026-09-22 (per `git show --stat 4e257c9` the commit re-touched `.last-update.json` + `index.md` + `quickstart.md` + `sources/README.md` + `sources/git-repo.md` + `sources/hackernews.md` + `sources/index.md` + `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/web-search.md` + `sources/wikijs.md` + `themes.md` + `themes/05-robin-research.md` + `themes/index.md` — the standard daily-update cycle that cleared 7 files from the prior 10-dirty baseline)
+| 2026-06-30 | 2b0e16ea | feat(精读): Cai 2026 Front Immunol 微流控芯片 + 肿瘤免疫治疗 |
-15. `d5a2b15` 2026-09-21 — chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-09-21, **thirty-eighth** consecutive sources-sync — the per `git show --stat d5a2b15` commit re-touched `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md` — the same 4 source-sync files)
+| 2026-06-30 | 8fa04f02 | feat(精读): Liu 2026 Front Immunol 多组学 + 空间转录组 + 类器官整合 |
-16. `5cc20ce` 2026-09-21 — chore: daily update 2026-09-21 (per `git show --stat 5cc20ce` the commit re-touched `.last-update.json` + `index.md` + `quickstart.md` + `sources/README.md` + `sources/git-repo.md` + `sources/hackernews.md` + `sources/index.md` + `sources/openwiki-version-drift.md` + `sources/web-search.md` + `themes.md` + `themes/05-robin-research.md` + `themes/index.md` — the standard daily-update cycle that cleared 6 files from the prior 12-dirty baseline)
+| 2026-06-30 | 247ebcea | feat(精读): He 2026 Gastroenterology 胃癌类器官 + In Vivo CRISPR 筛选 |
-17. `95f286d` 2026-09-20 — chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-09-20, **thirty-seventh** consecutive sources-sync — the per `git show --stat 95f286d` commit re-touched `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md` — the same 4 source-sync files)
+| 2026-06-30 | c7c03dfa | feat(精读): Zhao 2026 Front Med 肾类器官综述 |
-18. `49e3f63` 2026-09-20 — chore: daily update 2026-09-20 (per `git show --stat 49e3f63` the commit re-touched `.last-update.json` + `sources/README.md` + `sources/git-repo.md` + `sources/hackernews.md` + `sources/index.md` + `sources/web-search.md` + `themes.md` + `themes/05-robin-research.md` + `themes/index.md` + `quickstart.md` — the standard daily-update cycle)
+| 2026-06-28 | 4029857b | feat: 类器官-MEA 界面综述 — 心脏 Shell MEA (KB 6 文献融合) |
-19. `6e2a733` 2026-09-19 — chore: daily update 2026-09-19 (per `git show --stat 6e2a733` the commit re-touched `.last-update.json` + `index.md` + `quickstart.md` + `sources/README.md` + `sources/git-repo.md` + `sources/hackernews.md` + `sources/index.md` + `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/web-search.md` + `sources/wikijs.md` + `themes.md` + `themes/05-robin-research.md` + `themes/index.md` — the standard daily-update cycle; the commit cleared the prior 11-dirty-file baseline down to 5-dirty)
+| 2026-06-28 | 75690496 | fix: Raguin 论文 Fig 1-7 share-link → 真实验图 v3 重传 |
-20. `1ba0fb1` 2026-09-19 — chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-09-19, **thirty-sixth** consecutive sources-sync — the per `git show --stat 1ba0fb1` commit re-touched `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md` — the same 4 source-sync files)
+| 2026-06-28 | 1427da9f | feat: 精读 Raguin J et al. Cell Rep Methods 2026 — 血管化 + microglia 脑类器官 / GBM 放疗响应 |
-21. `c6e81a5` 2026-09-18 — chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-09-18, **thirty-fifth** consecutive sources-sync)
+| 2026-06-09 | 377a9798 | deep-read: CelVivo-47 视频销售拜访速查手册 2026-06-08.pdf |
-22. `46a508d` 2026-09-18 — chore: daily update 2026-09-18 (per `git show --stat 46a508d` the commit re-touched `.last-update.json` + `index.md` + `quickstart.md` + `sources/git-repo.md` + `sources/hackernews.md` + `sources/index.md` + `sources/literature.md` + `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/web-search.md` + `sources/wikijs.md` + `themes.md` — the standard daily-update cycle)
+| 2026-06-08 | ac82a01c | deep-read: Data Slide Deck Sales (Distributor Presentation).pdf |
-23. `307e038` 2026-09-17 — chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-09-17, **thirty-fourth** consecutive sources-sync)
+| 2026-06-08 | cea6cd57 | deep-read: Clinostar_Introductory_KPL_Translate.pdf |
-24. `3d95e56` 2026-09-17 — chore: daily update 2026-09-17 (per `git show --stat 3d95e56` the commit re-touched `index.md` + `quickstart.md` + `themes.md` + `sources/hackernews.md` + `sources/index.md` + `sources/literature.md` + `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/web-search.md` + `sources/wikijs.md` + `themes/05-robin-research.md` + `themes/index.md` + the `.last-update.json` metadata file — the standard daily-update cycle)
+| 2026-06-07 | 9d70899a | deep-read: Publications _ 3Brain(2).pdf |
-25. `ac46732` 2026-09-16 — chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-09-16, **thirty-third** consecutive sources-sync)
+| 2026-06-06 | c7511548 | deep-read: Brain-White-Paper_digital_2024_final.pdf |
-26. `73dae5e` 2026-09-16 — chore: daily update 2026-09-16 (per `git show --stat 73dae5e` the commit re-touched the same source-sync files)
+| 2026-06-06 | 0772ead7 | deep-read: 001_Protocol_Cultivating_Spheroids_and_Organoids.pdf |
-27. `f5465f9` 2026-09-15 — chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-09-15, **thirty-second** consecutive sources-sync)
+| 2026-06-06 | c086f69e | deep-read: 002_Protocol_Cultivating_Cells_in_2D.pdf |
 | 2026-06-06 | 067ef921 | deep-read: 003_Protocol_Preparation_of_ClinoReactor.pdf |
 | 2026-06-06 | de209c2f | deep-read: 004_Protocol_Media_Change_in_ClinoReactor.pdf |
 | 2026-06-06 | 201978c6 | deep-read: 005_Protocol_Splitting-Spheroids-and-Organoids.pdf |
-## Synthesis-policy — this run (2026-09-30T18:24Z)
+Pattern: every commit since late May is either a vendor-paper deep read (CelVivo
 protocol PDFs, 3Brain publications, Cellink reports) or a peer-reviewed paper
 deep read routed into `04-Literature/Deep-Reads/`. Sales training material lives
 under `06-Sales/Content/Training-Materials/` and is added in batches without
 commits (the recent `工业客户开发手册`, `Robin稿生成通字稿`, `销售基础话术包`, and
 `CelVivo赋能培训` runs are visible only as working-tree additions on this branch).
- **Vault delta: 0 new vault commits + 1 working-tree modification persisting** — vault HEAD unchanged at `09bec367` for the **19th consecutive fetch** after the Tomas 2026 + Vijakumaran 2026 resumption on 2026-09-11T18:14Z. **19 calendar days of vault silence** since the 2026-09-11 resumption (the 2026-09-29T18:14Z fetch recorded 18 calendar days; +1 calendar day from 2026-09-29 → 2026-09-30). The same MOC-file modification that surfaced at the 2026-09-13T18:08Z fetch (`M "04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md"`, mtime 2026-09-13 11:55:42 +0800) **persists uncommitted for 17 calendar days** at this fetch — Robin is editing the MOC index file but the modification has not been promoted to a commit. No new vault mtime changes were observed in the 2026-09-29T18:14Z → 2026-09-30T18:24Z 24-hour window. The 8 untracked regional agent files from 2026-08-07 (per the source-specific instruction "Track vault + OpenWiki wiki mtime + commits (Robin 8-07 added)") continue to carry forward unchanged: `02-Clients/Agents/全国经销商地图-2026-0807.md` (1310 bytes) + `02-Clients/Agents/华东-2026-0807.md` (10030 bytes) + `02-Clients/Agents/华北-2026-0807.md` (13057 bytes) + `02-Clients/Agents/华南-2026-0807.md` (10744 bytes) + `02-Clients/Agents/山东-2026-0807.md` (8592 bytes) + `02-Clients/Agents/湖北-2026-0807.md` (5766 bytes) + `02-Clients/Agents/西北-2026-0807.md` (2287 bytes) + `02-Clients/Agents/西南-2026-0807.md` (2657 bytes) — all dated 2026-08-07 20:24:19 +0800, documented in [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md). The new 2 untracked vault files noted at the 2026-09-24T18:07Z fetch (`04-Literature/Deep-Reads/Brain/2026-08-06_Parfitt_GM_et_al_NatCommun_2024_DJ1_LOF_midbrain_organoid_PD.md` 15972 bytes + `04-Literature/Deep-Reads/MOCs/papamichail-2025-organoids-on-chip.md` 13143 bytes) continue to carry forward unchanged from the 2026-09-24T18:07Z fetch — both pre-date the 2026-09-24 fetch and have been in the vault working tree since 2026-08-06 / 2026-09-13 respectively without being promoted to commits.
+## Changed files (this run)
 - **Wiki delta: automated maintenance only** (1 daily update + 1 sources-sync). The 2 new wiki commits in the 24-hour window are routine: `5c788cc` daily update 2026-09-30 + `1d3c470` sources-sync 2026-09-30 — the **forty-seventh** consecutive sources-sync (continuing the count-data wipe pattern that started at the 2026-08-15 `2507925` commit). The wiki HEAD bump `2fccbf017` → `1d3c470b` covers 1 calendar day.
 - **Dirty-file baseline change**: 13-dirty baseline (at 2026-09-29T18:14Z) → **11-dirty baseline** (at 2026-09-30T18:24Z). The `5c788cc` daily update committed `sources/git-repo.md` + `sources/README.md` + `sources/literature.md` + the `tmp/check_themes.py` deletion (clearing 4 entries from the dirty list; the standard 16-file cycle per `git show --stat 5c788cc` re-touched the standard synthesis-layer files including `sources/git-repo.md` + `sources/README.md` + `sources/literature.md` + `themes.md` + `themes/05-robin-research.md` + `themes/index.md`); the daily update also deleted `tmp/check_themes.py` from the working tree (deleted in commit; this is now in the dirty list as `D tmp/check_themes.py` at the post-commit state — but the post-sources-sync synthesis-side write path then re-touched `themes.md`). The `1d3c470` sources-sync re-touched the 4 source-sync files (`sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md`); the post-sources-sync synthesis-side write path re-touched `index.md` + `quickstart.md` + `sources/hackernews.md` + `sources/index.md` + `sources/web-search.md` + `themes.md`; the CLI metadata cycle re-touched `.last-update.json`. The 11-dirty-file list at 2026-09-30T18:24Z: `M .last-update.json` + `M index.md` + `M quickstart.md` + `M sources/hackernews.md` + `M sources/index.md` + `M sources/nocodb.md` + `M sources/ragflow.md` + `M sources/seafile.md` + `M sources/web-search.md` + `M sources/wikijs.md` + `M themes.md`. (Note: the standard `5c788cc` daily update cycle cleared `sources/git-repo.md` + `sources/README.md` + `sources/literature.md` + the `tmp/check_themes.py` deletion from the dirty list — net 4 files cleared — while the `1d3c470` sources-sync that landed after the daily update re-dirtied the 4 source-sync files + 6 synthesis-side files re-touched by the post-commit write path (`index.md` + `quickstart.md` + `sources/hackernews.md` + `sources/index.md` + `sources/web-search.md` + `themes.md`) = net −2 vs the 13-dirty baseline.)
 - **Carry-forward bump** to **49/44/44/37-day** at this fetch (highest carry-forward durations of the 2026-08-07 streak, +1 day from the 2026-09-29 fetch's 48/43/43/36-day): `Review/zhou2023_computer_vision_microfluidics.md` 48 → **49-day** (47 → **48 fetches silent**), `celvivo_commercial/` + `templates/` 43 → **44-day** (44 → **45 fetches silent** each), `deepread_40240593/` 36 → **37-day** (35 → **36 consecutive silent fetches** since creation; mtime unchanged at 2026-08-24 16:31 +0800).
 - **Synthesis-layer impact**: **none** — vault delta is empty (no new commits, no new mtime changes) and the wiki delta is automated maintenance only. The MOC-file working-tree modification persists uncommitted for 17 calendar days; it does not affect synthesis-layer pages until the commit lands. No `/themes.md` row, no `/commitments.md` row, no `/open-questions.md` row, no `/personal-logistics.md` item is added at this fetch.
  - **`/quickstart.md`** gets a new "Latest update — git-repo-1 (2026-09-30T18:24Z)" paragraph + the description frontmatter mentions the 2026-09-30T18:24Z git-repo-1 fetch + the **46th git-repo-1 fetch** of the 2026-08-07 streak + the **vault-silent-for-19th-consecutive-fetch** event + the 2 new wiki commits (46th/47th sources-sync sequence: `5c788cc` daily update + `1d3c470` sources-sync forty-seventh) + the 49/44/44/37-day carry-forward bump + the 11-dirty-file baseline + the MOC-file working-tree modification persisting uncommitted for 17 calendar days + the Robin 8-07 added untracked regional agent files
  - **`/sources/git-repo.md`** (this page) — description frontmatter refreshed to mention the 2026-09-30T18:24Z fetch; tags refreshed to add `2026-09-30`, `vault-silent-19d-consecutive-fetch`, `forty-seventh-sources-sync-2026-09-30`, `forty-sixth-git-repo-fetch-46th`, `wiki-2-new-commits`, `moc-organoid-3d-culture-uncommitted-edit-17d`, `deepread-40240593-thirty-seven-silent-fetches`, `dirty-11-files-baseline-2026-09-30`, `robin-8-07-added-untracked-regional-agent-files`; timestamp refreshed to `2026-09-30T18:24:00Z`; Source-config vault/wiki HEADs refreshed; Latest-manifest section refreshed; Carry-forward table bumped to 49/44/44/37-day; Recent-commits-wiki table refreshed (2 new commits at top); this Synthesis-policy section added; Previous-run section updated
  - **`/themes/05-robin-research.md`** — frontmatter description refreshed to mention the 2026-09-30T18:24Z fetch + the vault HEAD unchanged for the 19th consecutive fetch + the 2 new wiki commits (46th/47th sources-sync sequence) + the 49/44/44/37-day carry-forward bump + the MOC-file working-tree modification persisting uncommitted for 17 calendar days; 04-Literature/Deep-Reads/ breakdown table refreshed with the 49/44/44/37-day carry-forward bump
  - **`/sources/index.md`** — refreshed the git-repo.md description entry to reflect the 2026-09-30T18:24Z fetch + the vault HEAD unchanged at `09bec367` for the 19th consecutive fetch + the wiki HEAD `1d3c470b` + the 49/44/44/37-day carry-forward bump + the **46th git-repo-1 fetch** of the 2026-08-07 streak + the 11-dirty-file baseline
  - **`/sources/README.md`** — refreshed Active connectors Git repo row + Connector roll Git repo row to mention the 2026-09-30T18:24Z fetch + the **forty-seventh** consecutive sources-sync + the 11-dirty-file baseline + the 49/44/44/37-day carry-forward bump
 - Wiki edits: see the corresponding "Latest update — git-repo-1 (2026-09-30T18:24Z)" paragraph on `/quickstart.md` for the full delta list.
-## Synthesis-policy — this run (2026-09-29T18:14Z)
+Since the prior fetch (2026-08-02T18:11:41), HEAD is unchanged. The current
 manifest still reports the existing `skills/openclaw-workspace` modification;
 the ITX directory and five untracked files listed below are carryovers, and no
 new path was observed in this run:
- **Vault delta: 0 new vault commits + 1 working-tree modification persisting** — vault HEAD unchanged at `09bec367` for the **18th consecutive fetch** after the Tomas 2026 + Vijakumaran 2026 resumption on 2026-09-11T18:14Z. **18 calendar days of vault silence** since the 2026-09-11 resumption (the 2026-09-28T18:09Z fetch recorded 17 calendar days; +1 calendar day from 2026-09-28 → 2026-09-29). The same MOC-file modification that surfaced at the 2026-09-13T18:08Z fetch (`M "04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md"`, mtime 2026-09-13 11:55:42 +0800) **persists uncommitted for 16 calendar days** at this fetch — Robin is editing the MOC index file but the modification has not been promoted to a commit. No new vault mtime changes were observed in the 2026-09-28T18:09Z → 2026-09-29T18:14Z 24-hour window. The 8 untracked regional agent files from 2026-08-07 (per the source-specific instruction "Track vault + OpenWiki wiki mtime + commits (Robin 8-07 added)") continue to carry forward unchanged: `02-Clients/Agents/全国经销商地图-2026-0807.md` (1310 bytes) + `02-Clients/Agents/华东-2026-0807.md` (10030 bytes) + `02-Clients/Agents/华北-2026-0807.md` (13057 bytes) + `02-Clients/Agents/华南-2026-0807.md` (10744 bytes) + `02-Clients/Agents/山东-2026-0807.md` (8592 bytes) + `02-Clients/Agents/湖北-2026-0807.md` (5766 bytes) + `02-Clients/Agents/西北-2026-0807.md` (2287 bytes) + `02-Clients/Agents/西南-2026-0807.md` (2657 bytes) — all dated 2026-08-07 20:24:19 +0800, documented in [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md). The new 2 untracked vault files noted at the 2026-09-24T18:07Z fetch (`04-Literature/Deep-Reads/Brain/2026-08-06_Parfitt_GM_et_al_NatCommun_2024_DJ1_LOF_midbrain_organoid_PD.md` 15972 bytes + `04-Literature/Deep-Reads/MOCs/papamichail-2025-organoids-on-chip.md` 13143 bytes) continue to carry forward unchanged from the 2026-09-24T18:07Z fetch — both pre-date the 2026-09-24 fetch and have been in the vault working tree since 2026-08-06 / 2026-09-13 respectively without being promoted to commits.
+| Path | Change | Note |
- **Wiki delta: automated maintenance only** (1 daily update + 1 sources-sync). The 2 new wiki commits in the 24-hour window are routine: `92874d2` daily update 2026-09-29 + `2fccbf0` sources-sync 2026-09-29 — the **forty-sixth** consecutive sources-sync (continuing the count-data wipe pattern that started at the 2026-08-15 `2507925` commit). The wiki HEAD bump `6bafbff` → `2fccbf0` covers 1 calendar day.
+| --- | --- | --- |
- **Dirty-file baseline change**: 12-dirty baseline (at 2026-09-28T18:09Z) → **13-dirty baseline** (at 2026-09-29T18:14Z). The `92874d2` daily update committed `themes.md` (clearing it from the dirty list; the standard 16-file cycle per `git show --stat 92874d2` re-touched the same synthesis-layer files as the prior daily update including `themes.md` + `themes/05-robin-research.md` + `themes/index.md`); the daily update also removed `tmp/check_themes.py` from the working tree (deleted in commit; this is the new entry in the dirty list). The `2fccbf0` sources-sync re-touched the 4 source-sync files (`sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md`); the post-sources-sync synthesis-side write path re-touched `index.md` + `quickstart.md` + `sources/README.md` + `sources/hackernews.md` + `sources/index.md` + `sources/literature.md` + `sources/web-search.md`; the CLI metadata cycle re-touched `.last-update.json`. The 13-dirty-file list at 2026-09-29T18:14Z: `M .last-update.json` + `M index.md` + `M quickstart.md` + `M sources/README.md` + `M sources/hackernews.md` + `M sources/index.md` + `M sources/literature.md` + `M sources/nocodb.md` + `M sources/ragflow.md` + `M sources/seafile.md` + `M sources/web-search.md` + `M sources/wikijs.md` + `D tmp/check_themes.py`. (Note: the standard `92874d2` daily update cycle cleared `themes.md` from the dirty list, but the `2fccbf0` sources-sync that landed after the daily update re-dirtied the 4 source-sync files plus 7 synthesis-side files re-touched by the post-commit write path + the `tmp/check_themes.py` deletion that the daily update committed = net +1 vs the 12-dirty baseline because the daily update cleared `themes.md` while the sources-sync + post-commit write path re-touched `sources/README.md` + `sources/literature.md` that the daily update had not re-touched and added the `tmp/check_themes.py` deletion.)
+| `03-Resources/ITX-24h-Host/ITX_24h_Host_v18_Config_2026-07-31.md` | untracked (carryover) | Robin's 24h ITX Hermes-host build config |
- **Carry-forward bump** to **48/43/43/36-day** at this fetch (highest carry-forward durations of the 2026-08-07 streak, +1 day from the 2026-09-28 fetch's 47/42/42/35-day): `Review/zhou2023_computer_vision_microfluidics.md` 47 → **48-day** (46 → **47 fetches silent**), `celvivo_commercial/` + `templates/` 42 → **43-day** (43 → **44 fetches silent** each), `deepread_40240593/` 35 → **36-day** (34 → **35 consecutive silent fetches** since creation; mtime unchanged at 2026-08-24 16:31 +0800).
+| `skills/openclaw-workspace` | modified (carryover) | nested workspace remains dirty at recorded commit `4e81a914b5f4ed52d88e0b31476354f92fcd4be7`; content-level changes are out of scope for this index |
- **Synthesis-layer impact**: **none** — vault delta is empty (no new commits, no new mtime changes) and the wiki delta is automated maintenance only. The MOC-file working-tree modification persists uncommitted for 16 calendar days; it does not affect synthesis-layer pages until the commit lands. No `/themes.md` row, no `/commitments.md` row, no `/open-questions.md` row, no `/personal-logistics.md` item is added at this fetch.
+| `04-Literature/Deep-Reads/3Brain/3Brain_Sample_Holder_Set_PressNet_2026-07-07.md` | untracked (carryover) | 3Brain UK GB2624872 Sample Holder Set / CorePlate 压网装置 note |
-  - **`/quickstart.md`** gets a new "Latest update — git-repo-1 (2026-09-29T18:14Z)" paragraph + the description frontmatter mentions the 2026-09-29T18:14Z git-repo-1 fetch + the **45th git-repo-1 fetch** of the 2026-08-07 streak + the **vault-silent-for-18th-consecutive-fetch** event + the 2 new wiki commits (45th/46th sources-sync sequence: `92874d2` daily update + `2fccbf0` sources-sync forty-sixth) + the 48/43/43/36-day carry-forward bump + the 13-dirty-file baseline + the MOC-file working-tree modification persisting uncommitted for 16 calendar days + the Robin 8-07 added untracked regional agent files
+| `04-Literature/Deep-Reads/3Brain/Raji_2026_hMOs_dopaminergic_3Brain_MEA_2026-07-27.md` | untracked (carryover) | Raji 2026 Mol Psychiatry — WNT-modulated hMOs + 3Brain HD-MEA (Accura-3D 4096 electrodes) |
-  - **`/sources/git-repo.md`** (this page) — description frontmatter refreshed to mention the 2026-09-29T18:14Z fetch; tags refreshed to add `2026-09-29`, `vault-silent-18d-consecutive-fetch`, `forty-sixth-sources-sync-2026-09-29`, `forty-fifth-git-repo-fetch-45th`, `wiki-2-new-commits`, `moc-organoid-3d-culture-uncommitted-edit-16d`, `deepread-40240593-thirty-six-silent-fetches`, `dirty-13-files-baseline-2026-09-29`, `robin-8-07-added-untracked-regional-agent-files`; timestamp refreshed to `2026-09-29T18:14:00Z`; Source-config vault/wiki HEADs refreshed; Latest-manifest section refreshed; Carry-forward table bumped to 48/43/43/36-day; Recent-commits-wiki table refreshed (2 new commits at top); this Synthesis-policy section added; Previous-run section updated
+| `04-Literature/Deep-Reads/Cellink/Tasevska_2025_HCTZ_3D_printed_extended_release_2026-07-27.md` | untracked (carryover) | Tasevska 2025 EJPS — SSE-printed HCTZ extended-release tablets, BIO X-compatible |
-  - **`/themes/05-robin-research.md`** — frontmatter description refreshed to mention the 2026-09-29T18:14Z fetch + the vault HEAD unchanged for the 18th consecutive fetch + the 2 new wiki commits (45th/46th sources-sync sequence) + the 48/43/43/36-day carry-forward bump + the MOC-file working-tree modification persisting uncommitted for 16 calendar days; 04-Literature/Deep-Reads/ breakdown table refreshed with the 48/43/43/36-day carry-forward bump
+| `04-Literature/Deep-Reads/Celvivo/Bosnjakovic_2025_PAH_3D_spheroid_CelVivo_ClinoStar_2026-07-27.md` | untracked (carryover) | Bosnjakovic 2025 bioRxiv — HepG2 3D spheroid (ClinoStar dynamic culture) + PAH exposure |
-  - **`/sources/index.md`** — refreshed the git-repo.md description entry to reflect the 2026-09-29T18:14Z fetch + the vault HEAD unchanged at `09bec367` for the 18th consecutive fetch + the wiki HEAD `2fccbf0` + the 48/43/43/36-day carry-forward bump + the **45th git-repo-1 fetch** of the 2026-08-07 streak + the 13-dirty-file baseline
+| `OpenWiki速查手册_2026-07-27.md` | untracked (carryover) | Robin's OpenWiki cheat sheet (vault root) |
  - **`/sources/README.md`** — refreshed Active connectors Git repo row + Connector roll Git repo row to mention the 2026-09-29T18:14Z fetch + the **forty-sixth** consecutive sources-sync + the 13-dirty-file baseline + the 48/43/43/36-day carry-forward bump
 - Wiki edits: see the corresponding "Latest update — git-repo-1 (2026-09-29T18:14Z)" paragraph on `/quickstart.md` for the full delta list.
-## Synthesis-policy — this run (2026-09-28T18:09Z)
+In addition, the 4 commits added on 2026-07-28 brought these files into
 `main` (visible in `git log` and the manifest's `recentCommits` field, not
 in the `git status` dirty tree):
- **Vault delta: 0 new vault commits + 1 working-tree modification persisting** — vault HEAD unchanged at `09bec367` for the **17th consecutive fetch** after the Tomas 2026 + Vijakumaran 2026 resumption on 2026-09-11T18:14Z. **17 calendar days of vault silence** since the 2026-09-11 resumption (the 2026-09-27T18:19Z fetch recorded 16 calendar days; +1 calendar day from 2026-09-27 → 2026-09-28). The same MOC-file modification that surfaced at the 2026-09-13T18:08Z fetch (`M "04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md"`, mtime 2026-09-13 11:55:42 +0800) **persists uncommitted for 15 calendar days** at this fetch — Robin is editing the MOC index file but the modification has not been promoted to a commit. No new vault mtime changes were observed in the 2026-09-27T18:19Z → 2026-09-28T18:09Z 24-hour window. The 8 untracked regional agent files from 2026-08-07 (per the source-specific instruction "Track vault + OpenWiki wiki mtime + commits (Robin 8-07 added)") continue to carry forward unchanged: `02-Clients/Agents/全国经销商地图-2026-0807.md` (1310 bytes) + `02-Clients/Agents/华东-2026-0807.md` (10030 bytes) + `02-Clients/Agents/华北-2026-0807.md` (13057 bytes) + `02-Clients/Agents/华南-2026-0807.md` (10744 bytes) + `02-Clients/Agents/山东-2026-0807.md` (8592 bytes) + `02-Clients/Agents/湖北-2026-0807.md` (5766 bytes) + `02-Clients/Agents/西北-2026-0807.md` (2287 bytes) + `02-Clients/Agents/西南-2026-0807.md` (2657 bytes) — all dated 2026-08-07 20:24:19 +0800, documented in [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md). The new 2 untracked vault files noted at the 2026-09-24T18:07Z fetch (`04-Literature/Deep-Reads/Brain/2026-08-06_Parfitt_GM_et_al_NatCommun_2024_DJ1_LOF_midbrain_organoid_PD.md` 15972 bytes + `04-Literature/Deep-Reads/MOCs/papamichail-2025-organoids-on-chip.md` 13143 bytes) continue to carry forward unchanged from the 2026-09-24T18:07Z fetch — both pre-date the 2026-09-24 fetch and have been in the vault working tree since 2026-08-06 / 2026-09-13 respectively without being promoted to commits.
+| Path | Change | Note |
- **Wiki delta: automated maintenance only** (1 daily update + 1 sources-sync). The 2 new wiki commits in the 24-hour window are routine: `53fd10c` daily update 2026-09-28 + `6bafbff` sources-sync 2026-09-28 — the **forty-fifth** consecutive sources-sync (continuing the count-data wipe pattern that started at the 2026-08-15 `2507925` commit). The wiki HEAD bump `057a35ef` → `6bafbff` covers 1 calendar day.
+| --- | --- | --- |
- **Dirty-file baseline change**: 12-dirty baseline (at 2026-09-27T18:19Z) → **12-dirty baseline** (at 2026-09-28T18:09Z). The `53fd10c` daily update committed `sources/openwiki-version-drift.md` (clearing it from the dirty list; the standard 17-file cycle per `git show --stat 53fd10c` re-touched the same synthesis-layer files as the prior daily update including `themes.md` + `themes/05-robin-research.md` + `themes/index.md`); the daily update also added `home/index.md` + `home/ldw/index.md` + `home/ldw/replace_quickstart_prior.py` + `tmp/replace_quickstart_prior.py` (untracked artifacts that are tracked only via the `git show --stat` output but excluded from the manifest `changedFiles` array). The `6bafbff` sources-sync re-touched the 4 source-sync files (`sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md`); the post-sources-sync synthesis-side write path re-touched `index.md` + `quickstart.md` + `sources/hackernews.md` + `sources/index.md` + `sources/literature.md` + `sources/web-search.md` + `themes.md`; the CLI metadata cycle re-touched `.last-update.json`. The 12-dirty-file list at 2026-09-28T18:09Z: `M .last-update.json` + `M index.md` + `M quickstart.md` + `M sources/hackernews.md` + `M sources/index.md` + `M sources/literature.md` + `M sources/nocodb.md` + `M sources/ragflow.md` + `M sources/seafile.md` + `M sources/web-search.md` + `M sources/wikijs.md` + `M themes.md`. The raw `status` output also shows `?? home/index.md` + `?? home/ldw/index.md` + `?? home/ldw/replace_quickstart_prior.py` + `?? tmp/replace_quickstart_prior.py` as new untracked entries but the manifest `changedFiles` array excludes untracked entries so the modified-file count stays at 12. (Note: the standard `53fd10c` daily update cycle cleared `sources/openwiki-version-drift.md` from the dirty list, but the `6bafbff` sources-sync that landed after the daily update re-dirtied the 4 source-sync files plus 7 synthesis-side files re-touched by the post-commit write path = net 0 vs the 12-dirty baseline because the daily update cleared `sources/openwiki-version-drift.md` while the sources-sync + post-commit write path re-touched `themes.md` that the daily update had committed.)
+| `02-Clients/Agents/董慧群.md` | added (commit `21491578`) | new CelVivo distributor technical-contact profile (mostly 待补) |
- **Carry-forward bump** to **47/42/42/35-day** at this fetch (highest carry-forward durations of the 2026-08-07 streak, +1 day from the 2026-09-27 fetch's 46/41/41/34-day): `Review/zhou2023_computer_vision_microfluidics.md` 46 → **47-day** (45 → **46 fetches silent**), `celvivo_commercial/` + `templates/` 41 → **42-day** (42 → **43 fetches silent** each), `deepread_40240593/` 34 → **35-day** (33 → **34 consecutive silent fetches** since creation; mtime unchanged at 2026-08-24 16:31 +0800).
+| `04-Literature/Deep-Reads/Other/2026-07-28_Parate_2020_SCRT_PEMF_MSC_paracrine_cartilage.md` | added (commit `652e0e60`) | Parate 2020 Stem Cell Res Ther — PEMF增强MSC旁分泌功能促软骨再生 |
- **Synthesis-layer impact**: **none** — vault delta is empty (no new commits, no new mtime changes) and the wiki delta is automated maintenance only. The MOC-file working-tree modification persists uncommitted for 15 calendar days; it does not affect synthesis-layer pages until the commit lands. No `/themes.md` row, no `/commitments.md` row, no `/open-questions.md` row, no `/personal-logistics.md` item is added at this fetch.
+| `04-Literature/Deep-Reads/Other/2026-07-28_Lee_2025_FrontVetSci_canine_MSC_3D_spheroid.md` | added (commit `ee34cf83`) | Lee 2025 Front Vet Sci — 犬脂肪源MSC 3D球体 (Wiki.js Id=1645, NocoDB Id=3290) |
-  - **`/quickstart.md`** gets a new "Latest update — git-repo-1 (2026-09-28T18:09Z)" paragraph + the description frontmatter mentions the 2026-09-28T18:09Z git-repo-1 fetch + the **44th git-repo-1 fetch** of the 2026-08-07 streak + the **vault-silent-for-17th-consecutive-fetch** event + the 2 new wiki commits (44th/45th sources-sync sequence: `53fd10c` daily update + `6bafbff` sources-sync forty-fifth) + the 47/42/42/35-day carry-forward bump + the 12-dirty-file baseline + the MOC-file working-tree modification persisting uncommitted for 15 calendar days + the Robin 8-07 added untracked regional agent files
+| `04-Literature/Deep-Reads/RegenMed/2026-07-28_Hodge_2025_RegenMed_MSC_3D_Bio-Block.md` | added (commit `5ddda558`) | Hodge 2025 RegenMed — Bio-Block 4周MSC长期培养对比 (Wiki.js + SeaFile 7图 PDF) |
  - **`/sources/git-repo.md`** (this page) — description frontmatter refreshed to mention the 2026-09-28T18:09Z fetch; tags refreshed to add `2026-09-28`, `vault-silent-17d-consecutive-fetch`, `forty-fifth-sources-sync-2026-09-28`, `forty-fourth-git-repo-fetch-44th`, `wiki-2-new-commits`, `moc-organoid-3d-culture-uncommitted-edit-15d`, `deepread-40240593-thirty-five-silent-fetches`, `dirty-12-files-baseline-2026-09-28`, `robin-8-07-added-untracked-regional-agent-files`; timestamp refreshed to `2026-09-28T18:09:00Z`; Source-config vault/wiki HEADs refreshed; Latest-manifest section refreshed; Carry-forward table bumped to 47/42/42/35-day; Recent-commits-wiki table refreshed (2 new commits at top); this Synthesis-policy section added; Previous-run section updated
  - **`/themes/05-robin-research.md`** — frontmatter description refreshed to mention the 2026-09-28T18:09Z fetch + the vault HEAD unchanged for the 17th consecutive fetch + the 2 new wiki commits (44th/45th sources-sync sequence) + the 47/42/42/35-day carry-forward bump + the MOC-file working-tree modification persisting uncommitted for 15 calendar days; 04-Literature/Deep-Reads/ breakdown table refreshed with the 47/42/42/35-day carry-forward bump
  - **`/sources/index.md`** — refreshed the git-repo.md description entry to reflect the 2026-09-28T18:09Z fetch + the vault HEAD unchanged at `09bec367` for the 17th consecutive fetch + the wiki HEAD `6bafbff` + the 47/42/42/35-day carry-forward bump + the **44th git-repo-1 fetch** of the 2026-08-07 streak + the 12-dirty-file baseline
  - **`/sources/README.md`** — refreshed Active connectors Git repo row + Connector roll Git repo row to mention the 2026-09-28T18:09Z fetch + the **forty-fifth** consecutive sources-sync + the 12-dirty-file baseline + the 47/42/42/35-day carry-forward bump
 - Wiki edits: see the corresponding "Latest update — git-repo-1 (2026-09-28T18:09Z)" paragraph on `/quickstart.md` for the full delta list.
-## Synthesis-policy — this run (2026-09-27T18:19Z)
+The 2 commits added on 2026-07-29 brought this file into `main` (visible
 in `git log` and the manifest's `recentCommits` field, not in the
 `git status` dirty tree):
- **Vault delta: 0 new vault commits + 1 working-tree modification persisting** — vault HEAD unchanged at `09bec367` for the **16th consecutive fetch** after the Tomas 2026 + Vijakumaran 2026 resumption on 2026-09-11T18:14Z. **16 calendar days of vault silence** since the 2026-09-11 resumption (the 2026-09-26T18:09Z fetch recorded 15 calendar days; +1 calendar day from 2026-09-26 → 2026-09-27). The same MOC-file modification that surfaced at the 2026-09-13T18:08Z fetch (`M "04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md"`, mtime 2026-09-13 11:55:42 +0800) **persists uncommitted for 14 calendar days** at this fetch — Robin is editing the MOC index file but the modification has not been promoted to a commit. No new vault mtime changes were observed in the 2026-09-26T18:09Z → 2026-09-27T18:19Z 24-hour window. The 8 untracked regional agent files from 2026-08-07 (per the source-specific instruction "Track vault + OpenWiki wiki mtime + commits (Robin 8-07 added)") continue to carry forward unchanged: `02-Clients/Agents/全国经销商地图-2026-0807.md` (1310 bytes) + `02-Clients/Agents/华东-2026-0807.md` (10030 bytes) + `02-Clients/Agents/华北-2026-0807.md` (13057 bytes) + `02-Clients/Agents/华南-2026-0807.md` (10744 bytes) + `02-Clients/Agents/山东-2026-0807.md` (8592 bytes) + `02-Clients/Agents/湖北-2026-0807.md` (5766 bytes) + `02-Clients/Agents/西北-2026-0807.md` (2287 bytes) + `02-Clients/Agents/西南-2026-0807.md` (2657 bytes) — all dated 2026-08-07 20:24:19 +0800, documented in [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md). The new 2 untracked vault files noted at the 2026-09-24T18:07Z fetch (`04-Literature/Deep-Reads/Brain/2026-08-06_Parfitt_GM_et_al_NatCommun_2024_DJ1_LOF_midbrain_organoid_PD.md` 15972 bytes + `04-Literature/Deep-Reads/MOCs/papamichail-2025-organoids-on-chip.md` 13143 bytes) continue to carry forward unchanged from the 2026-09-24T18:07Z fetch — both pre-date the 2026-09-24 fetch and have been in the vault working tree since 2026-08-06 / 2026-09-13 respectively without being promoted to commits.
+| Path | Change | Note |
- **Wiki delta: automated maintenance only** (1 daily update + 1 sources-sync). The 2 new wiki commits in the 24-hour window are routine: `3e52ff2` daily update 2026-09-27 + `057a35e` sources-sync 2026-09-27 — the **forty-fourth** consecutive sources-sync (continuing the count-data wipe pattern that started at the 2026-08-15 `2507925` commit). The wiki HEAD bump `4becee017` → `057a35ef` covers 1 calendar day.
+| --- | --- | --- |
- **Dirty-file baseline change**: 11-dirty baseline (at 2026-09-26T18:09Z) → **12-dirty baseline** (at 2026-09-27T18:19Z). The `3e52ff2` daily update committed `themes.md` (clearing it from the dirty list; the standard 15-file cycle per `git show --stat 3e52ff2` re-touched the same synthesis-layer files as the prior daily update including `themes.md` + `themes/05-robin-research.md` + `themes/index.md`); the daily update also added `tmp/check_themes.py` + `tmp/index.md` (untracked artifacts that are tracked only via the `git show --stat` output but excluded from the manifest `changedFiles` array). The `057a35e` sources-sync re-touched the 4 source-sync files (`sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md`); the post-sources-sync synthesis-side write path re-touched `index.md` + `quickstart.md` + `sources/hackernews.md` + `sources/index.md` + `sources/literature.md` + `sources/openwiki-version-drift.md` + `sources/web-search.md`; the CLI metadata cycle re-touched `.last-update.json`. The 12-dirty-file list at 2026-09-27T18:19Z: `M .last-update.json` + `M index.md` + `M quickstart.md` + `M sources/hackernews.md` + `M sources/index.md` + `M sources/literature.md` + `M sources/nocodb.md` + `M sources/openwiki-version-drift.md` + `M sources/ragflow.md` + `M sources/seafile.md` + `M sources/web-search.md` + `M sources/wikijs.md`. The raw `status` output also shows `?? home/` + `?? tmp/replace_quickstart_prior.py` as new untracked entries but the manifest `changedFiles` array excludes untracked entries so the modified-file count stays at 12. (Note: the standard `3e52ff2` daily update cycle cleared `themes.md` from the dirty list, but the `057a35e` sources-sync that landed after the daily update re-dirtied the 4 source-sync files plus 7 synthesis-side files re-touched by the post-commit write path = net +1 vs the 11-dirty baseline because the daily update cleared `themes.md` while the sources-sync + post-commit write path re-touched `sources/literature.md` + `sources/openwiki-version-drift.md` that the daily update had not re-touched.)
+| `04-Literature/Deep-Reads/Organoid/2026-07-29_Organoids_disease_modeling_treatment_2026_review.md` | added (commit `81671c69`) then modified (commit `1a81e485`) | Organoids for disease modeling and treatment 2026 综述 (PMID 41545895, PMC12828948); commit `1a81e485` is the SOP-rewrite pass (按主题分块 + 三段式 + 落款) |
 - **Carry-forward bump** to **46/41/41/34-day** at this fetch (highest carry-forward durations of the 2026-08-07 streak, +1 day from the 2026-09-26 fetch's 45/40/40/33-day): `Review/zhou2023_computer_vision_microfluidics.md` 45 → **46-day** (44 → **45 fetches silent**), `celvivo_commercial/` + `templates/` 40 → **41-day** (41 → **42 fetches silent** each), `deepread_40240593/` 33 → **34-day** (32 → **33 consecutive silent fetches** since creation; mtime unchanged at 2026-08-24 16:31 +0800).
 - **Synthesis-layer impact**: **none** — vault delta is empty (no new commits, no new mtime changes) and the wiki delta is automated maintenance only. The MOC-file working-tree modification persists uncommitted for 14 calendar days; it does not affect synthesis-layer pages until the commit lands. No `/themes.md` row, no `/commitments.md` row, no `/open-questions.md` row, no `/personal-logistics.md` item is added at this fetch.
  - **`/quickstart.md`** gets a new "Latest update — git-repo-1 (2026-09-27T18:19Z)" paragraph + the description frontmatter mentions the 2026-09-27T18:19Z git-repo-1 fetch + the **43rd git-repo-1 fetch** of the 2026-08-07 streak + the **vault-silent-for-16th-consecutive-fetch** event + the 2 new wiki commits (43rd/44th sources-sync sequence: `3e52ff2` daily update + `057a35e` sources-sync forty-fourth) + the 46/41/41/34-day carry-forward bump + the 12-dirty-file baseline + the MOC-file working-tree modification persisting uncommitted for 14 calendar days + the Robin 8-07 added untracked regional agent files
  - **`/sources/git-repo.md`** (this page) — description frontmatter refreshed to mention the 2026-09-27T18:19Z fetch; tags refreshed to add `2026-09-27`, `vault-silent-16d-consecutive-fetch`, `forty-fourth-sources-sync-2026-09-27`, `forty-third-git-repo-fetch-43rd`, `wiki-2-new-commits`, `moc-organoid-3d-culture-uncommitted-edit-14d`, `deepread-40240593-thirty-four-silent-fetches`, `dirty-12-files-baseline-2026-09-27`, `robin-8-07-added-untracked-regional-agent-files`; timestamp refreshed to `2026-09-27T18:19:00Z`; Source-config vault/wiki HEADs refreshed; Latest-manifest section refreshed; Carry-forward table bumped to 46/41/41/34-day; Recent-commits-wiki table refreshed (2 new commits at top); this Synthesis-policy section added; Previous-run section updated
  - **`/themes/05-robin-research.md`** — frontmatter description refreshed to mention the 2026-09-27T18:19Z fetch + the vault HEAD unchanged for the 16th consecutive fetch + the 2 new wiki commits (43rd/44th sources-sync sequence) + the 46/41/41/34-day carry-forward bump + the MOC-file working-tree modification persisting uncommitted for 14 calendar days; 04-Literature/Deep-Reads/ breakdown table refreshed with the 46/41/41/34-day carry-forward bump
  - **`/sources/index.md`** — refreshed the git-repo.md description entry to reflect the 2026-09-27T18:19Z fetch + the vault HEAD unchanged at `09bec367` for the 16th consecutive fetch + the wiki HEAD `057a35ef` + the 46/41/41/34-day carry-forward bump + the **43rd git-repo-1 fetch** of the 2026-08-07 streak + the 12-dirty-file baseline
  - **`/sources/README.md`** — refreshed Active connectors Git repo row + Connector roll Git repo row to mention the 2026-09-27T18:19Z fetch + the **forty-fourth** consecutive sources-sync + the 12-dirty-file baseline + the 46/41/41/34-day carry-forward bump
 - Wiki edits: see the corresponding "Latest update — git-repo-1 (2026-09-27T18:19Z)" paragraph on `/quickstart.md` for the full delta list.
-## Synthesis-policy — this run (2026-09-26T18:09Z)
+## Notable entities surfaced by the vault (structural hints only)
- **Vault delta: 0 new vault commits + 1 working-tree modification persisting** — vault HEAD unchanged at `09bec367` for the **15th consecutive fetch** after the Tomas 2026 + Vijakumaran 2026 resumption on 2026-09-11T18:14Z. **15 calendar days of vault silence** since the 2026-09-11 resumption (the 2026-09-25T18:17Z fetch recorded 14 calendar days; +1 calendar day from 2026-09-25 → 2026-09-26). The same MOC-file modification that surfaced at the 2026-09-13T18:08Z fetch (`M "04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md"`, mtime 2026-09-13 11:55:42 +0800) **persists uncommitted for 13 calendar days** at this fetch — Robin is editing the MOC index file but the modification has not been promoted to a commit. No new vault mtime changes were observed in the 2026-09-25T18:17Z → 2026-09-26T18:09Z 24-hour window. The 8 untracked regional agent files from 2026-08-07 (per the source-specific instruction "Track vault + OpenWiki wiki mtime + commits (Robin 8-07 added)") continue to carry forward unchanged: `02-Clients/Agents/全国经销商地图-2026-0807.md` (1310 bytes) + `02-Clients/Agents/华东-2026-0807.md` (10030 bytes) + `02-Clients/Agents/华北-2026-0807.md` (13057 bytes) + `02-Clients/Agents/华南-2026-0807.md` (10744 bytes) + `02-Clients/Agents/山东-2026-0807.md` (8592 bytes) + `02-Clients/Agents/湖北-2026-0807.md` (5766 bytes) + `02-Clients/Agents/西北-2026-0807.md` (2287 bytes) + `02-Clients/Agents/西南-2026-0807.md` (2657 bytes) — all dated 2026-08-07 20:24:19 +0800, documented in [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md). The new 2 untracked vault files noted at the 2026-09-24T18:07Z fetch (`04-Literature/Deep-Reads/Brain/2026-08-06_Parfitt_GM_et_al_NatCommun_2024_DJ1_LOF_midbrain_organoid_PD.md` 15972 bytes + `04-Literature/Deep-Reads/MOCs/papamichail-2025-organoids-on-chip.md` 13143 bytes) continue to carry forward unchanged from the 2026-09-24T18:07Z fetch — both pre-date the 2026-09-24 fetch and have been in the vault working tree since 2026-08-06 / 2026-09-13 respectively without being promoted to commits.
+- **CelVivo industrial customers program** — a dedicated subfolder under
- **Wiki delta: automated maintenance only** (1 daily update + 1 sources-sync). The 2 new wiki commits in the 24-hour window are routine: `41347af` daily update 2026-09-26 + `4becee0` sources-sync 2026-09-26 — the **forty-third** consecutive sources-sync (continuing the count-data wipe pattern that started at the 2026-08-15 `2507925` commit). The wiki HEAD bump `f9bb2e5e` → `4becee017` covers 1 calendar day.
+  `05-Documents/Products/Celvivo/Industrial-Customers/` holds `CelVivo_中国工业
- **Dirty-file baseline change**: 12-dirty baseline (at 2026-09-25T18:17Z) → **11-dirty baseline** (at 2026-09-26T18:09Z). The `41347af` daily update cleared `sources/README.md` from the dirty list (the standard 15-file cycle per `git show --stat 41347af` re-touched the same synthesis-layer files as the prior daily update plus `themes.md`). The `4becee0` sources-sync re-touched the 4 source-sync files (`sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md`); the post-sources-sync synthesis-side write path re-touched `index.md` + `quickstart.md` + `sources/hackernews.md` + `sources/index.md` + `sources/web-search.md` + `themes.md`; the CLI metadata cycle re-touched `.last-update.json`. The 11-dirty-file list at 2026-09-26T18:09Z: `M .last-update.json` + `M index.md` + `M quickstart.md` + `M sources/hackernews.md` + `M sources/index.md` + `M sources/nocodb.md` + `M sources/ragflow.md` + `M sources/seafile.md` + `M sources/web-search.md` + `M sources/wikijs.md` + `M themes.md`. The raw `status` output also shows `?? tmp/` as a new untracked directory but the manifest `changedFiles` array excludes untracked entries so the modified-file count stays at 11. (Note: the standard `41347af` daily update cycle cleared the prior 12-dirty baseline down to a smaller count, but the `4becee0` sources-sync that landed after the daily update re-dirtied the 4 source-sync files plus 6 synthesis-side files re-touched by the post-commit write path = net −1 vs the 12-dirty baseline because the daily update cleared `sources/README.md` while the sources-sync did not re-touch it.)
+  客户开发研究报告` (v1 + v2), `客户管线定位_1页图`, and `工业客户开发手册-v3`.
- **Carry-forward bump** to **45/40/40/33-day** at this fetch (highest carry-forward durations of the 2026-08-07 streak, +1 day from the 2026-09-25 fetch's 44/39/39/32-day): `Review/zhou2023_computer_vision_microfluidics.md` 44 → **45-day** (43 → **44 fetches silent**), `celvivo_commercial/` + `templates/` 39 → **40-day** (40 → **41 fetches silent** each), `deepread_40240593/` 32 → **33-day** (31 → **32 consecutive silent fetches** since creation; mtime unchanged at 2026-08-24 16:31 +0800).
+  This is a self-contained CelVivo China commercial effort.
- **Synthesis-layer impact**: **none** — vault delta is empty (no new commits, no new mtime changes) and the wiki delta is automated maintenance only. The MOC-file working-tree modification persists uncommitted for 13 calendar days; it does not affect synthesis-layer pages until the commit lands. No `/themes.md` row, no `/commitments.md` row, no `/open-questions.md` row, no `/personal-logistics.md` item is added at this fetch.
+- **CelVivo sales training cluster** — `06-Sales/Content/Training-Materials/`
-  - **`/quickstart.md`** gets a new "Latest update — git-repo-1 (2026-09-26T18:09Z)" paragraph + the description frontmatter mentions the 2026-09-26T18:09Z git-repo-1 fetch + the **42nd git-repo-1 fetch** of the 2026-08-07 streak + the **vault-silent-for-15th-consecutive-fetch** event + the 2 new wiki commits (42nd/43rd sources-sync sequence: `41347af` daily update + `4becee0` sources-sync forty-third) + the 45/40/40/33-day carry-forward bump + the 11-dirty-file baseline + the MOC-file working-tree modification persisting uncommitted for 13 calendar days + the Robin 8-07 added untracked regional agent files
+  contains a `Robin稿生成通字稿` family (v3–v6), a `CelVivo赋能培训` PowerPoint
-  - **`/sources/git-repo.md`** (this page) — description frontmatter refreshed to mention the 2026-09-26T18:09Z fetch; tags refreshed to add `2026-09-26`, `vault-silent-15d-consecutive-fetch`, `forty-third-sources-sync-2026-09-26`, `forty-second-git-repo-fetch-42nd`, `wiki-2-new-commits`, `moc-organoid-3d-culture-uncommitted-edit-13d`, `deepread-40240593-thirty-three-silent-fetches`, `dirty-11-files-baseline-2026-09-26`, `robin-8-07-added-untracked-regional-agent-files`; timestamp refreshed to `2026-09-26T18:09:00Z`; Source-config vault/wiki HEADs refreshed; Latest-manifest section refreshed; Carry-forward table bumped to 45/40/40/33-day; Recent-commits-wiki table refreshed (2 new commits at top); this Synthesis-policy section added; Previous-run section updated
+  family (v1–v9, depth-flavored edits), and a `销售基础话术包` pair. Versions
-  - **`/themes/05-robin-research.md`** — frontmatter description refreshed to mention the 2026-09-26T18:09Z fetch + the vault HEAD unchanged for the 15th consecutive fetch + the 2 new wiki commits (42nd/43rd sources-sync sequence) + the 45/40/40/33-day carry-forward bump + the MOC-file working-tree modification persisting uncommitted for 13 calendar days; 04-Literature/Deep-Reads/ breakdown table refreshed with the 45/40/40/33-day carry-forward bump
+  progress from 基础 → 5大管线 → 深度版 → 终稿修正 → 销量仅看.
-  - **`/sources/index.md`** — refreshed the git-repo.md description entry to reflect the 2026-09-26T18:09Z fetch + the vault HEAD unchanged at `09bec367` for the 15th consecutive fetch + the wiki HEAD `4becee017` + the 45/40/40/33-day carry-forward bump + the **42nd git-repo-1 fetch** of the 2026-08-07 streak + the 11-dirty-file baseline
+- **3Brain end-customer dossier set** — 11+ dossiers under
-  - **`/sources/README.md`** — refreshed Active connectors Git repo row + Connector roll Git repo row to mention the 2026-09-26T18:09Z fetch + the **forty-third** consecutive sources-sync + the 11-dirty-file baseline + the 45/40/40/33-day carry-forward bump
+  `03-Resources/End-Customers/` covering 神经所 (上海), 北京大学, 北京天坛医院,
- Wiki edits: see the corresponding "Latest update — git-repo-1 (2026-09-26T18:09Z)" paragraph on `/quickstart.md` for the full delta list.
+  浙大一附院, 中科院昆明动物所, 西南医科大学, 贵州医科大学, plus TCM accounts
  at 云南中医药大学 and 天津创新中药.
 - **CelVivo distributor technical contact (new 2026-07-28)** — `02-Clients/Agents/董慧群.md`
  is the first profile under the `02-Clients/Agents/` bucket (frontmatter
  `type: agent`, role: 代理商技术同事, products: CelVivo ClinoStar /
  ClinoReactor). Robin was told about 董慧群 via WeChat DM on 2026-07-28 —
  role is to help push CelVivo products at the technical / demo / selection
  stage. The profile is mostly 待补 (agency name, region, phone, WeChat,
  customers, opportunities are all empty placeholders). Logged as an open
  question on `/open-questions.md` because the agent can not reason about
  CelVivo-channel activity without these fields.
 - **ITX 24h host build (first observed 2026-07-31; still untracked)** —
  `03-Resources/ITX-24h-Host/ITX_24h_Host_v18_Config_2026-07-31.md` is a
  top-level bucket first observed between the 2026-07-30T18:13 fetch and the
  2026-07-31T18:08 fetch; it remains untracked. Single file: Robin's personal
  24h server build plan for hosting Hermes Agent + AI workflow stack — mATX +
  i5-12400 + DDR4-2666 32G + 板载 Realtek 1Gb + Intel PRO/1000 GT 双网卡 NAS
  隔离, ¥2,985.82, 10/11 parts arrived, planned hostnames/roles:
  192.168.31.100 (主力机 SSH) vs 10.10.10.254 (RAGFlow / NAS RAGFlow API).
  Workflow-tooling priority LOW (not vendor-anchored), so it does **not** earn a
  `/themes.md` row, but the build remains a source-anchored personal-infra work
  item and was promoted to `/commitments.md` as
  `itx-24h-host-build-2026-q3` (Owner: me) for the post-assembly steps (Ubuntu
  Server 22.04 install + 双网卡静态 IP + Hermes Agent install + 24h soak test).
 - **CellSweep** — referenced in the wiki goal focus areas; not surfaced as a
  top-level vault folder in this run, so it likely lives under `Work/` or
  `scripts/` (outside the navigation index).
-## Synthesis-policy — this run (2026-09-25T18:17Z)
+## Synthesis policy for this source
- **Vault delta: 0 new vault commits + 1 working-tree modification persisting** — vault HEAD unchanged at `09bec367` for the **14th consecutive fetch** after the Tomas 2026 + Vijakumaran 2026 resumption on 2026-09-11T18:14Z. **14 calendar days of vault silence** since the 2026-09-11 resumption (the 2026-09-24T18:07Z fetch recorded 13 calendar days; +1 calendar day from 2026-09-24 → 2026-09-25). The same MOC-file modification that surfaced at the 2026-09-13T18:08Z fetch (`M "04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md"`, mtime 2026-09-13 11:55:42 +0800) **persists uncommitted for 12 calendar days** at this fetch — Robin is editing the MOC index file but the modification has not been promoted to a commit. No new vault mtime changes were observed in the 2026-09-24T18:07Z → 2026-09-25T18:17Z 24-hour window. The 8 untracked regional agent files from 2026-08-07 (per the source-specific instruction "Track vault + OpenWiki wiki mtime + commits (Robin 8-07 added)") continue to carry forward unchanged: `02-Clients/Agents/全国经销商地图-2026-0807.md` (1310 bytes) + `02-Clients/Agents/华东-2026-0807.md` (10030 bytes) + `02-Clients/Agents/华北-2026-0807.md` (13057 bytes) + `02-Clients/Agents/华南-2026-0807.md` (10744 bytes) + `02-Clients/Agents/山东-2026-0807.md` (8592 bytes) + `02-Clients/Agents/湖北-2026-0807.md` (5766 bytes) + `02-Clients/Agents/西北-2026-0807.md` (2287 bytes) + `02-Clients/Agents/西南-2026-0807.md` (2657 bytes) — all dated 2026-08-07 20:24:19 +0800, documented in [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md). The new 2 untracked vault files noted at the 2026-09-24T18:07Z fetch (`04-Literature/Deep-Reads/Brain/2026-08-06_Parfitt_GM_et_al_NatCommun_2024_DJ1_LOF_midbrain_organoid_PD.md` 15972 bytes + `04-Literature/Deep-Reads/MOCs/papamichail-2025-organoids-on-chip.md` 13143 bytes) continue to carry forward unchanged from the 2026-09-24T18:07Z fetch — both pre-date the 2026-09-24 fetch and have been in the vault working tree since 2026-08-06 / 2026-09-13 respectively without being promoted to commits.
+- **This run (2026-08-03):** no new entries in `/themes.md`,
- **Wiki delta: automated maintenance only** (1 daily update + 1 sources-sync). The 2 new wiki commits in the 24-hour window are routine: `069eef3` daily update 2026-09-25 + `f9bb2e5` sources-sync 2026-09-25 — the **forty-second** consecutive sources-sync (continuing the count-data wipe pattern that started at the 2026-08-15 `2507925` commit). The wiki HEAD bump `17e9fafc` → `f9bb2e5e` covers 1 calendar day.
+  `/open-questions.md`, `/commitments.md`, or `/personal-logistics.md`.
- **Dirty-file baseline change**: 12-dirty baseline (at 2026-09-24T18:07Z) → **11-dirty baseline** (at 2026-09-25T18:17Z). The `069eef3` daily update cleared `sources/git-repo.md` from the dirty list (the standard 15-file cycle per `git show --stat 069eef3` re-touched the same synthesis-layer files as the prior daily update plus `themes.md`). The `f9bb2e5` sources-sync re-touched the 4 source-sync files (`sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md`); the post-sources-sync synthesis-side write path re-touched `index.md` + `quickstart.md` + `sources/README.md` + `sources/hackernews.md` + `sources/index.md` + `sources/web-search.md` + `themes.md`; the CLI metadata cycle re-touched `.last-update.json`. The 11-dirty-file list at 2026-09-25T18:17Z: `M .last-update.json` + `M index.md` + `M quickstart.md` + `M sources/README.md` + `M sources/hackernews.md` + `M sources/index.md` + `M sources/nocodb.md` + `M sources/ragflow.md` + `M sources/seafile.md` + `M sources/web-search.md` + `M sources/wikijs.md` + `M themes.md`. (Note: the standard `069eef3` daily update cycle cleared the prior 12-dirty baseline down to a smaller count, but the `f9bb2e5` sources-sync that landed after the daily update re-dirtied the 4 source-sync files plus 7 synthesis-side files re-touched by the post-commit write path = net −1 vs the 12-dirty baseline because the daily update cleared `sources/git-repo.md` while the sources-sync did not re-touch it.)
+  The vault manifest is byte-identical to the 2026-08-02T18:11:41 fetch
- **Carry-forward bump** to **44/39/39/32-day** at this fetch (highest carry-forward durations of the 2026-08-07 streak, +1 day from the 2026-09-24 fetch's 43/38/38/31-day): `Review/zhou2023_computer_vision_microfluidics.md` 43 → **44-day** (42 → **43 fetches silent**), `celvivo_commercial/` + `templates/` 38 → **39-day** (39 → **40 fetches silent** each), `deepread_40240593/` 31 → **32-day** (30 → **31 consecutive silent fetches** since creation; mtime unchanged at 2026-08-24 16:31 +0800).
+  except for `generatedAt`, so nothing new to route. The existing
- **Synthesis-layer impact**: **none** — vault delta is empty (no new commits, no new mtime changes) and the wiki delta is automated maintenance only. The MOC-file working-tree modification persists uncommitted for 12 calendar days; it does not affect synthesis-layer pages until the commit lands. No `/themes.md` row, no `/commitments.md` row, no `/open-questions.md` row, no `/personal-logistics.md` item is added at this fetch.
+  `itx-24h-host-build-2026-q3` commitment remains valid because the source
-  - **`/quickstart.md`** gets a new "Latest update — git-repo-1 (2026-09-25T18:17Z)" paragraph + the description frontmatter mentions the 2026-09-25T18:17Z git-repo-1 fetch + the **41st git-repo-1 fetch** of the 2026-08-07 streak + the **vault-silent-for-14th-consecutive-fetch** event + the 2 new wiki commits (41st/42nd sources-sync sequence: `069eef3` daily update + `f9bb2e5` sources-sync forty-second) + the 44/39/39/32-day carry-forward bump + the 11-dirty-file baseline + the MOC-file working-tree modification persisting uncommitted for 12 calendar days + the Robin 8-07 added untracked regional agent files
+  file is still untracked and the post-assembly work is unfinished; it was
-  - **`/sources/git-repo.md`** (this page) — description frontmatter refreshed to mention the 2026-09-25T18:17Z fetch; tags refreshed to add `2026-09-25`, `vault-silent-14d-consecutive-fetch`, `forty-second-sources-sync-2026-09-25`, `forty-first-git-repo-fetch-41st`, `wiki-2-new-commits`, `moc-organoid-3d-culture-uncommitted-edit-12d`, `deepread-40240593-thirty-two-silent-fetches`, `dirty-11-files-baseline-2026-09-25`, `robin-8-07-added-untracked-regional-agent-files`; timestamp refreshed to `2026-09-25T18:17:00Z`; Source-config vault/wiki HEADs refreshed; Latest-manifest section refreshed; Carry-forward table bumped to 44/39/39/32-day; Recent-commits-wiki table refreshed (2 new commits at top); this Synthesis-policy section added; Previous-run section updated
+  promoted during the 2026-07-31 pull from the new build config.
-  - **`/themes/05-robin-research.md`** — frontmatter description refreshed to mention the 2026-09-25T18:17Z fetch + the vault HEAD unchanged for the 14th consecutive fetch + the 2 new wiki commits (41st/42nd sources-sync sequence) + the 44/39/39/32-day carry-forward bump + the MOC-file working-tree modification persisting uncommitted for 12 calendar days; 04-Literature/Deep-Reads/ breakdown table refreshed with the 44/39/39/32-day carry-forward bump
+- The vault is a knowledge base, not a live signal stream; durable
-  - **`/sources/index.md`** — refreshed the git-repo.md description entry to reflect the 2026-09-25T18:17Z fetch + the vault HEAD unchanged at `09bec367` for the 14th consecutive fetch + the wiki HEAD `f9bb2e5e` + the 44/39/39/32-day carry-forward bump + the **41st git-repo-1 fetch** of the 2026-08-07 streak + the 11-dirty-file baseline
+  per-document synthesis (paper deep reads, sales scripts, customer
-  - **`/sources/README.md`** — refreshed Active connectors Git repo row + Connector roll Git repo row to mention the 2026-09-25T18:17Z fetch + the **forty-second** consecutive sources-sync + the 11-dirty-file baseline + the 44/39/39/32-day carry-forward bump
+  files) requires reading individual files, which is delegated to the
- Wiki edits: see the corresponding "Latest update — git-repo-1 (2026-09-25T18:17Z)" paragraph on `/quickstart.md` for the full delta list.
+  Hermes skill and RAGFlow.
 - Future runs should keep this page structural. Promote a row to a canonical
  theme only when the connector observes a recurring workflow (e.g. weekly
  literature digest cadence, sales training iteration pattern) across multiple
  fetches.
-## Synthesis-policy — this run (2026-09-24T18:07Z)
+## Next update
- **Vault delta: 0 new vault commits + 1 working-tree modification persisting** — vault HEAD unchanged at `09bec367` for the **13th consecutive fetch** after the Tomas 2026 + Vijakumaran 2026 resumption on 2026-09-11T18:14Z. **13 calendar days of vault silence** since the 2026-09-11 resumption (the 2026-09-23T18:10Z fetch recorded 12 calendar days; +1 calendar day from 2026-09-23 → 2026-09-24). The same MOC-file modification that surfaced at the 2026-09-13T18:08Z fetch (`M "04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md"`, mtime 2026-09-13 11:55:42 +0800) **persists uncommitted for 11 calendar days** at this fetch — Robin is editing the MOC index file but the modification has not been promoted to a commit. No new vault mtime changes were observed in the 2026-09-23T18:10Z → 2026-09-24T18:07Z 24-hour window. The 8 untracked regional agent files from 2026-08-07 (per the source-specific instruction "Track vault + OpenWiki wiki mtime + commits (Robin 8-07 added)") continue to carry forward unchanged: `02-Clients/Agents/全国经销商地图-2026-0807.md` (1310 bytes) + `02-Clients/Agents/华东-2026-0807.md` (10030 bytes) + `02-Clients/Agents/华北-2026-0807.md` (13057 bytes) + `02-Clients/Agents/华南-2026-0807.md` (10744 bytes) + `02-Clients/Agents/山东-2026-0807.md` (8592 bytes) + `02-Clients/Agents/湖北-2026-0807.md` (5766 bytes) + `02-Clients/Agents/西北-2026-0807.md` (2287 bytes) + `02-Clients/Agents/西南-2026-0807.md` (2657 bytes) — all dated 2026-08-07 20:24:19 +0800, documented in [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md).
+Run `openwiki_ingest_connector connectorId=git-repo` (or
- **Wiki delta: automated maintenance only** (1 daily update + 1 sources-sync). The 2 new wiki commits in the 24-hour window are routine: `dc1a9fb` daily update 2026-09-24 + `17e9faf` sources-sync 2026-09-24 — the **forty-first** consecutive sources-sync (continuing the count-data wipe pattern that started at the 2026-08-15 `2507925` commit). The wiki HEAD bump `6aa1db2` → `17e9faf` covers 1 calendar day.
+`openwiki personal --update`) to refresh. Expect HEAD bump, refreshed
- **Dirty-file baseline change**: 10-dirty baseline (at 2026-09-23T18:10Z) → **12-dirty baseline** (at 2026-09-24T18:07Z). The `17e9faf` sources-sync re-touched the 4 source-sync files (`sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md`); the post-sources-sync synthesis-side write path re-touched `index.md` + `quickstart.md` + `sources/README.md` + `sources/hackernews.md` + `sources/index.md` + `sources/web-search.md` + `themes.md`; the CLI metadata cycle re-touched `.last-update.json`. The 12-dirty-file list at 2026-09-24T18:07Z: `M .last-update.json` + `M index.md` + `M quickstart.md` + `M sources/README.md` + `M sources/hackernews.md` + `M sources/index.md` + `M sources/nocodb.md` + `M sources/ragflow.md` + `M sources/seafile.md` + `M sources/web-search.md` + `M sources/wikijs.md` + `M themes.md`. (Note: the standard `dc1a9fb` daily update cycle cleared the prior 10-dirty baseline down to a smaller count, but the `17e9faf` sources-sync that landed after the daily update re-dirtied the 4 source-sync files plus 7 synthesis-side files re-touched by the post-commit write path = net +2 vs the 10-dirty baseline.)
+`recentCommits`, and updated working-tree status.
 - **Carry-forward bump** to **43/38/38/31-day** at this fetch (highest carry-forward durations of the 2026-08-07 streak, +1 day from the 2026-09-23 fetch's 42/37/37/30-day): `Review/zhou2023_computer_vision_microfluidics.md` 42 → **43-day** (40 → **41 fetches silent**), `celvivo_commercial/` + `templates/` 37 → **38-day** (37 → **38 fetches silent** each), `deepread_40240593/` 30 → **31-day** (29 → **30 consecutive silent fetches** since creation; mtime unchanged at 2026-08-24 16:31 +0800).
 - **Synthesis-layer impact**: **none** — vault delta is empty (no new commits, no new mtime changes) and the wiki delta is automated maintenance only. The MOC-file working-tree modification persists uncommitted for 11 calendar days; it does not affect synthesis-layer pages until the commit lands. No `/themes.md` row, no `/commitments.md` row, no `/open-questions.md` row, no `/personal-logistics.md` item is added at this fetch.
  - **`/quickstart.md`** gets a new "Latest update — git-repo-1 (2026-09-24T18:07Z)" paragraph + the description frontmatter mentions the 2026-09-24T18:07Z git-repo-1 fetch + the **40th git-repo-1 fetch** of the 2026-08-07 streak + the **vault-silent-for-13th-consecutive-fetch** event + the 2 new wiki commits (40th/41st sources-sync sequence: `dc1a9fb` daily update + `17e9faf` sources-sync forty-first) + the 43/38/38/31-day carry-forward bump + the 12-dirty-file baseline + the MOC-file working-tree modification persisting uncommitted for 11 calendar days + the Robin 8-07 added untracked regional agent files
  - **`/sources/git-repo.md`** (this page) — description frontmatter refreshed to mention the 2026-09-24T18:07Z fetch; tags refreshed to add `2026-09-24`, `vault-silent-13d-consecutive-fetch`, `forty-first-sources-sync-2026-09-24`, `fortieth-git-repo-fetch-40th`, `wiki-2-new-commits`, `moc-organoid-3d-culture-uncommitted-edit-11d`, `deepread-40240593-thirty-one-silent-fetches`, `dirty-12-files-baseline-2026-09-24`, `robin-8-07-added-untracked-regional-agent-files`; timestamp refreshed to `2026-09-24T18:07:00Z`; Source-config vault/wiki HEADs refreshed; Latest-manifest section refreshed; Carry-forward table bumped to 43/38/38/31-day; Recent-commits-wiki table refreshed (2 new commits at top); this Synthesis-policy section added; Previous-run section updated
  - **`/themes/05-robin-research.md`** — frontmatter description refreshed to mention the 2026-09-24T18:07Z fetch + the vault HEAD unchanged for the 13th consecutive fetch + the 2 new wiki commits (40th/41st sources-sync sequence) + the 43/38/38/31-day carry-forward bump + the MOC-file working-tree modification persisting uncommitted for 11 calendar days; 04-Literature/Deep-Reads/ breakdown table refreshed with the 43/38/38/31-day carry-forward bump
  - **`/sources/index.md`** — refreshed the git-repo.md description entry to reflect the 2026-09-24T18:07Z fetch + the vault HEAD unchanged at `09bec367` for the 13th consecutive fetch + the wiki HEAD `17e9fafc` + the 43/38/38/31-day carry-forward bump + the **40th git-repo-1 fetch** of the 2026-08-07 streak + the 12-dirty-file baseline
  - **`/sources/README.md`** — refreshed Active connectors Git repo row + Connector roll Git repo row to mention the 2026-09-24T18:07Z fetch + the **forty-first** consecutive sources-sync + the 12-dirty-file baseline + the 43/38/38/31-day carry-forward bump
 - Wiki edits: see the corresponding "Latest update — git-repo-1 (2026-09-24T18:07Z)" paragraph on `/quickstart.md` for the full delta list.
 ## Synthesis-policy — this run (2026-09-23T18:10Z)
 - **Vault delta: 0 new vault commits + 1 working-tree modification persisting** — vault HEAD unchanged at `09bec367` for the **12th consecutive fetch** after the Tomas 2026 + Vijakumaran 2026 resumption on 2026-09-11T18:14Z. **12 calendar days of vault silence** since the 2026-09-11 resumption (the 2026-09-22T18:08Z fetch recorded 11 calendar days; +1 calendar day from 2026-09-22 → 2026-09-23). The same MOC-file modification that surfaced at the 2026-09-13T18:08Z fetch (`M "04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md"`, mtime 2026-09-13 11:55:42 +0800) **persists uncommitted for 10 calendar days** at this fetch — Robin is editing the MOC index file but the modification has not been promoted to a commit. No new vault mtime changes were observed in the 2026-09-22T18:08Z → 2026-09-23T18:10Z 24-hour window. The 8 untracked regional agent files from 2026-08-07 (per the source-specific instruction "Track vault + OpenWiki wiki mtime + commits (Robin 8-07 added)") continue to carry forward unchanged: `02-Clients/Agents/全国经销商地图-2026-0807.md` (1310 bytes) + `02-Clients/Agents/华东-2026-0807.md` (10030 bytes) + `02-Clients/Agents/华北-2026-0807.md` (13057 bytes) + `02-Clients/Agents/华南-2026-0807.md` (10744 bytes) + `02-Clients/Agents/山东-2026-0807.md` (8592 bytes) + `02-Clients/Agents/湖北-2026-0807.md` (5766 bytes) + `02-Clients/Agents/西北-2026-0807.md` (2287 bytes) + `02-Clients/Agents/西南-2026-0807.md` (2657 bytes) — all dated 2026-08-07 20:24:19 +0800, documented in [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md).
 - **Wiki delta: automated maintenance only** (1 daily update + 1 sources-sync). The 2 new wiki commits in the 24-hour window are routine: `4c145e2` daily update 2026-09-23 + `6aa1db2` sources-sync 2026-09-23 — the **fortieth** consecutive sources-sync (continuing the count-data wipe pattern that started at the 2026-08-15 `2507925` commit). The wiki HEAD bump `4ee7fc1` → `6aa1db2` covers 1 calendar day.
 - **Dirty-file baseline change**: 8-dirty baseline (at 2026-09-22T18:08Z) → **10-dirty baseline** (at 2026-09-23T18:10Z). The `6aa1db2` sources-sync re-touched the 4 source-sync files (`sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md`); the post-sources-sync synthesis-side write path re-touched `quickstart.md` + `sources/README.md` + `sources/hackernews.md` + `sources/web-search.md`; the CLI metadata cycle re-touched `.last-update.json`; the sources index synthesis re-touched `sources/index.md`. The 10-dirty-file list at 2026-09-23T18:10Z: `M .last-update.json` + `M quickstart.md` + `M sources/README.md` + `M sources/hackernews.md` + `M sources/index.md` + `M sources/nocodb.md` + `M sources/ragflow.md` + `M sources/seafile.md` + `M sources/web-search.md` + `M sources/wikijs.md`. (Note: the standard `4c145e2` daily update cycle cleared the prior 8-dirty baseline down to a smaller count, but the `6aa1db2` sources-sync that landed after the daily update re-dirtied the 4 source-sync files plus 4 synthesis-side files re-touched by the post-commit write path = net +2 vs the 8-dirty baseline.)
 - **Carry-forward bump** to **42/37/37/30-day** at this fetch (highest carry-forward durations of the 2026-08-07 streak, +1 day from the 2026-09-22 fetch's 41/36/36/29-day): `Review/zhou2023_computer_vision_microfluidics.md` 41 → **42-day** (39 → **40 fetches silent**), `celvivo_commercial/` + `templates/` 36 → **37-day** (36 → **37 fetches silent** each), `deepread_40240593/` 29 → **30-day** (28 → **29 consecutive silent fetches** since creation; mtime unchanged at 2026-08-24 16:31 +0800).
 - **Synthesis-layer impact**: **none** — vault delta is empty (no new commits, no new mtime changes) and the wiki delta is automated maintenance only. The MOC-file working-tree modification persists uncommitted for 10 calendar days; it does not affect synthesis-layer pages until the commit lands. No `/themes.md` row, no `/commitments.md` row, no `/open-questions.md` row, no `/personal-logistics.md` item is added at this fetch.
  - **`/quickstart.md`** gets a new "Latest update — git-repo-1 (2026-09-23T18:10Z)" paragraph + the description frontmatter mentions the 2026-09-23T18:10Z git-repo-1 fetch + the **39th git-repo-1 fetch** of the 2026-08-07 streak + the **vault-silent-for-12th-consecutive-fetch** event + the 2 new wiki commits (39th/40th sources-sync sequence: `4c145e2` daily update + `6aa1db2` sources-sync fortieth) + the 42/37/37/30-day carry-forward bump + the 10-dirty-file baseline + the MOC-file working-tree modification persisting uncommitted for 10 calendar days + the Robin 8-07 added untracked regional agent files
  - **`/sources/git-repo.md`** (this page) — description frontmatter refreshed to mention the 2026-09-23T18:10Z fetch; tags refreshed to add `2026-09-23`, `vault-silent-12d-consecutive-fetch`, `fortieth-sources-sync-2026-09-23`, `thirty-ninth-git-repo-fetch-39th`, `wiki-2-new-commits`, `moc-organoid-3d-culture-uncommitted-edit-10d`, `deepread-40240593-thirty-silent-fetches`, `dirty-10-files-baseline-2026-09-23`, `robin-8-07-added-untracked-regional-agent-files`; timestamp refreshed to `2026-09-23T18:10:00Z`; Source-config vault/wiki HEADs refreshed; Latest-manifest section refreshed; Carry-forward table bumped to 42/37/37/30-day; Recent-commits-wiki table refreshed (2 new commits at top); this Synthesis-policy section added; Previous-run section updated
  - **`/themes/05-robin-research.md`** — frontmatter description refreshed to mention the 2026-09-23T18:10Z fetch + the vault HEAD unchanged for the 12th consecutive fetch + the 2 new wiki commits (39th/40th sources-sync sequence) + the 42/37/37/30-day carry-forward bump + the MOC-file working-tree modification persisting uncommitted for 10 calendar days; 04-Literature/Deep-Reads/ breakdown table refreshed with the 42/37/37/30-day carry-forward bump
  - **`/sources/index.md`** — refreshed the git-repo.md description entry to reflect the 2026-09-23T18:10Z fetch + the vault HEAD unchanged at `09bec367` for the 12th consecutive fetch + the wiki HEAD `6aa1db2` + the 42/37/37/30-day carry-forward bump + the **39th git-repo-1 fetch** of the 2026-08-07 streak + the 10-dirty-file baseline
  - **`/sources/README.md`** — refreshed Active connectors Git repo row + Connector roll Git repo row to mention the 2026-09-23T18:10Z fetch + the **fortieth** consecutive sources-sync + the 10-dirty-file baseline + the 42/37/37/30-day carry-forward bump
 - Wiki edits: see the corresponding "Latest update — git-repo-1 (2026-09-23T18:10Z)" paragraph on `/quickstart.md` for the full delta list.
 ## Synthesis-policy — this run (2026-09-22T18:08Z)
 - **Vault delta: 0 new vault commits + 1 working-tree modification persisting** — vault HEAD unchanged at `09bec367` for the **11th consecutive fetch** after the Tomas 2026 + Vijakumaran 2026 resumption on 2026-09-11T18:14Z. **11 calendar days of vault silence** since the 2026-09-11 resumption (the 2026-09-21T18:17Z fetch recorded 10 calendar days; +1 calendar day from 2026-09-21 → 2026-09-22). The same MOC-file modification that surfaced at the 2026-09-13T18:08Z fetch (`M "04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md"`, mtime 2026-09-13 11:55:42 +0800) **persists uncommitted for 9 calendar days** at this fetch — Robin is editing the MOC index file but the modification has not been promoted to a commit. No new vault mtime changes were observed in the 2026-09-21T18:17Z → 2026-09-22T18:08Z 24-hour window. The 8 untracked regional agent files from 2026-08-07 (per the source-specific instruction "Track vault + OpenWiki wiki mtime + commits (Robin 8-07 added)") continue to carry forward unchanged: `02-Clients/Agents/全国经销商地图-2026-0807.md` (1310 bytes) + `02-Clients/Agents/华东-2026-0807.md` (10030 bytes) + `02-Clients/Agents/华北-2026-0807.md` (13057 bytes) + `02-Clients/Agents/华南-2026-0807.md` (10744 bytes) + `02-Clients/Agents/山东-2026-0807.md` (8592 bytes) + `02-Clients/Agents/湖北-2026-0807.md` (5766 bytes) + `02-Clients/Agents/西北-2026-0807.md` (2287 bytes) + `02-Clients/Agents/西南-2026-0807.md` (2657 bytes) — all dated 2026-08-07 20:24:19 +0800, documented in [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md).
 - **Wiki delta: automated maintenance only** (1 daily update + 1 sources-sync). The 2 new wiki commits in the 24-hour window are routine: `4e257c9` daily update 2026-09-22 + `4ee7fc1` sources-sync 2026-09-22 — the **thirty-ninth** consecutive sources-sync (continuing the count-data wipe pattern that started at the 2026-08-15 `2507925` commit). The wiki HEAD bump `d5a2b15` → `4ee7fc1` covers 1 calendar day.
 - **Dirty-file baseline change**: 10-dirty baseline (at 2026-09-21T18:17Z) → **8-dirty baseline** (at 2026-09-22T18:08Z). The `4e257c9` daily update commit cleared `index.md` + `quickstart.md` + `sources/README.md` + `sources/git-repo.md` + `themes.md` + `themes/05-robin-research.md` + `themes/index.md` that the prior daily update had not been able to clean (those 7 files were in the 10-dirty list at 2026-09-21 because the `d5a2b15` sources-sync re-touched them or because the synthesis-side write path re-touched them after the daily update committed). The `4ee7fc1` sources-sync re-touched the 4 source-sync files (`sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md`); the synthesis-side write path did not re-touch any synthesis-layer files at this fetch (the post-commit dirty list is just the sources-sync + the CLI metadata cycle `.last-update.json` + the synthesis-layer pages that the sources-sync itself touches). The 8-dirty-file list at 2026-09-22T18:08Z: `M .last-update.json` + `M sources/hackernews.md` + `M sources/index.md` + `M sources/nocodb.md` + `M sources/ragflow.md` + `M sources/seafile.md` + `M sources/web-search.md` + `M sources/wikijs.md`.
 - **Carry-forward bump** to **41/36/36/29-day** at this fetch (highest carry-forward durations of the 2026-08-07 streak, +1 day from the 2026-09-21 fetch's 40/35/35/28-day): `Review/zhou2023_computer_vision_microfluidics.md` 40 → **41-day** (38 → **39 fetches silent**), `celvivo_commercial/` + `templates/` 35 → **36-day** (35 → **36 fetches silent** each), `deepread_40240593/` 28 → **29-day** (27 → **28 consecutive silent fetches** since creation; mtime unchanged at 2026-08-24 16:31 +0800).
 - **Synthesis-layer impact**: **none** — vault delta is empty (no new commits, no new mtime changes) and the wiki delta is automated maintenance only. The MOC-file working-tree modification persists uncommitted for 9 calendar days; it does not affect synthesis-layer pages until the commit lands. No `/themes.md` row, no `/commitments.md` row, no `/open-questions.md` row, no `/personal-logistics.md` item is added at this fetch.
  - **`/quickstart.md`** gets a new "Latest update — git-repo-1 (2026-09-22T18:08Z)" paragraph + the description frontmatter mentions the 2026-09-22T18:08Z git-repo-1 fetch + the **38th git-repo-1 fetch** of the 2026-08-07 streak + the **vault-silent-for-11th-consecutive-fetch** event + the 2 new wiki commits (38th/39th sources-sync sequence: `4e257c9` daily update + `4ee7fc1` sources-sync thirty-ninth) + the 41/36/36/29-day carry-forward bump + the 8-dirty-file baseline + the MOC-file working-tree modification persisting uncommitted for 9 calendar days + the Robin 8-07 added untracked regional agent files
  - **`/sources/git-repo.md`** (this page) — description frontmatter refreshed to mention the 2026-09-22T18:08Z fetch; tags refreshed to add `2026-09-22`, `vault-silent-11d-consecutive-fetch`, `thirty-ninth-sources-sync-2026-09-22`, `thirty-eighth-git-repo-fetch-38th`, `wiki-2-new-commits`, `moc-organoid-3d-culture-uncommitted-edit-9d`, `deepread-40240593-twenty-nine-silent-fetches`, `dirty-8-files-baseline-2026-09-22`, `robin-8-07-added-untracked-regional-agent-files`; timestamp refreshed to `2026-09-22T18:08:00Z`; Source-config vault/wiki HEADs refreshed; Latest-manifest section refreshed; Carry-forward table bumped to 41/36/36/29-day; Recent-commits-wiki table refreshed (2 new commits at top); this Synthesis-policy section added; Previous-run section updated
  - **`/themes/05-robin-research.md`** — frontmatter description refreshed to mention the 2026-09-22T18:08Z fetch + the vault HEAD unchanged for the 11th consecutive fetch + the 2 new wiki commits (38th/39th sources-sync sequence) + the 41/36/36/29-day carry-forward bump + the MOC-file working-tree modification persisting uncommitted for 9 calendar days; 04-Literature/Deep-Reads/ breakdown table refreshed with the 41/36/36/29-day carry-forward bump
  - **`/sources/index.md`** — refreshed the git-repo.md description entry to reflect the 2026-09-22T18:08Z fetch + the vault HEAD unchanged at `09bec367` for the 11th consecutive fetch + the wiki HEAD `4ee7fc1` + the 41/36/36/29-day carry-forward bump + the **38th git-repo-1 fetch** of the 2026-08-07 streak + the 8-dirty-file baseline
  - **`/sources/README.md`** — refreshed Active connectors Git repo row + Connector roll Git repo row to mention the 2026-09-22T18:08Z fetch + the **thirty-ninth** consecutive sources-sync + the 8-dirty-file baseline + the 41/36/36/29-day carry-forward bump
 - Wiki edits: see the corresponding "Latest update — git-repo-1 (2026-09-22T18:08Z)" paragraph on `/quickstart.md` for the full delta list.
 ## Synthesis-policy — this run (2026-09-21T18:17Z)
 - **Vault delta: 0 new vault commits + 1 working-tree modification persisting** — vault HEAD unchanged at `09bec367` for the **10th consecutive fetch** after the Tomas 2026 + Vijakumaran 2026 resumption on 2026-09-11T18:14Z. **10 calendar days of vault silence** since the 2026-09-11 resumption (the 2026-09-20T18:07Z fetch recorded 9 calendar days; +1 calendar day from 2026-09-20 → 2026-09-21). The same MOC-file modification that surfaced at the 2026-09-13T18:08Z fetch (`M "04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md"`, mtime 2026-09-13 11:55:42 +0800) **persists uncommitted for 8 calendar days** at this fetch — Robin is editing the MOC index file but the modification has not been promoted to a commit. No new vault mtime changes were observed in the 2026-09-20T18:07Z → 2026-09-21T18:17Z 24-hour window. The 8 untracked regional agent files from 2026-08-07 (per the source-specific instruction "Track vault + OpenWiki wiki mtime + commits (Robin 8-07 added)") continue to carry forward unchanged: `02-Clients/Agents/全国经销商地图-2026-0807.md` (1310 bytes) + `02-Clients/Agents/华东-2026-0807.md` (10030 bytes) + `02-Clients/Agents/华北-2026-0807.md` (13057 bytes) + `02-Clients/Agents/华南-2026-0807.md` (10744 bytes) + `02-Clients/Agents/山东-2026-0807.md` (8592 bytes) + `02-Clients/Agents/湖北-2026-0807.md` (5766 bytes) + `02-Clients/Agents/西北-2026-0807.md` (2287 bytes) + `02-Clients/Agents/西南-2026-0807.md` (2657 bytes) — all dated 2026-08-07 20:24:19 +0800, documented in [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md).
 - **Wiki delta: automated maintenance only** (1 daily update + 1 sources-sync). The 2 new wiki commits in the 24-hour window are routine: `5cc20ce` daily update 2026-09-21 + `d5a2b15` sources-sync 2026-09-21 — the **thirty-eighth** consecutive sources-sync (continuing the count-data wipe pattern that started at the 2026-08-15 `2507925` commit). The wiki HEAD bump `95f286d` → `d5a2b15` covers 1 calendar day.
 - **Dirty-file baseline change**: 12-dirty baseline (at 2026-09-20T18:07Z) → **10-dirty baseline** (at 2026-09-21T18:17Z). The `5cc20ce` daily update commit cleared `index.md` + `sources/README.md` + `sources/git-repo.md` + `sources/openwiki-version-drift.md` + `themes/05-robin-research.md` + `themes/index.md` that the prior daily update had not been able to clean (those 6 files were in the 12-dirty list at 2026-09-20 because the `95f286d` sources-sync re-touched them or because the synthesis-side write path re-touched them after the daily update committed). The `d5a2b15` sources-sync re-touched the 4 source-sync files (`sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md`); the synthesis-side write path re-touched `quickstart.md` + `themes.md` + `sources/index.md` + `sources/hackernews.md` + `sources/web-search.md`. The 10-dirty-file list at 2026-09-21T18:17Z: `M .last-update.json` + `M quickstart.md` + `M sources/hackernews.md` + `M sources/index.md` + `M sources/nocodb.md` + `M sources/ragflow.md` + `M sources/seafile.md` + `M sources/web-search.md` + `M sources/wikijs.md` + `M themes.md`.
 - **Carry-forward bump** to **40/35/35/28-day** at this fetch (highest carry-forward durations of the 2026-08-07 streak, +1 day from the 2026-09-20 fetch's 39/34/34/27-day): `Review/zhou2023_computer_vision_microfluidics.md` 39 → **40-day** (37 → **38 fetches silent**), `celvivo_commercial/` + `templates/` 34 → **35-day** (34 → **35 fetches silent** each), `deepread_40240593/` 27 → **28-day** (26 → **27 consecutive silent fetches** since creation; mtime unchanged at 2026-08-24 16:31 +0800).
 - **Synthesis-layer impact**: **none** — vault delta is empty (no new commits, no new mtime changes) and the wiki delta is automated maintenance only. The MOC-file working-tree modification persists uncommitted for 8 calendar days; it does not affect synthesis-layer pages until the commit lands. No `/themes.md` row, no `/commitments.md` row, no `/open-questions.md` row, no `/personal-logistics.md` item is added at this fetch.
  - **`/quickstart.md`** gets a new "Latest update — git-repo-1 (2026-09-21T18:17Z)" paragraph + the description frontmatter mentions the 2026-09-21T18:17Z git-repo-1 fetch + the **37th git-repo-1 fetch** of the 2026-08-07 streak + the **vault-silent-for-10th-consecutive-fetch** event + the 2 new wiki commits (37th/38th sources-sync sequence: `5cc20ce` daily update + `d5a2b15` sources-sync thirty-eighth) + the 40/35/35/28-day carry-forward bump + the 10-dirty-file baseline + the MOC-file working-tree modification persisting uncommitted for 8 calendar days + the Robin 8-07 added untracked regional agent files
  - **`/sources/git-repo.md`** (this page) — description frontmatter refreshed to mention the 2026-09-21T18:17Z fetch; tags refreshed to add `2026-09-21`, `vault-silent-10d-consecutive-fetch`, `thirty-eighth-sources-sync-2026-09-21`, `thirty-seventh-git-repo-fetch-37th`, `wiki-2-new-commits`, `moc-organoid-3d-culture-uncommitted-edit-8d`, `deepread-40240593-twenty-eight-silent-fetches`, `robin-8-07-added-untracked-regional-agent-files`; timestamp refreshed to `2026-09-21T18:17:00Z`; Source-config vault/wiki HEADs refreshed; Latest-manifest section refreshed; Carry-forward table bumped to 40/35/35/28-day; Recent-commits-wiki table refreshed (2 new commits at top); this Synthesis-policy section added; Previous-run section updated
  - **`/themes/05-robin-research.md`** — frontmatter description refreshed to mention the 2026-09-21T18:17Z fetch + the vault HEAD unchanged for the 10th consecutive fetch + the 2 new wiki commits (37th/38th sources-sync sequence) + the 40/35/35/28-day carry-forward bump + the MOC-file working-tree modification persisting uncommitted for 8 calendar days; 04-Literature/Deep-Reads/ breakdown table refreshed with the 40/35/35/28-day carry-forward bump
  - **`/sources/index.md`** — refreshed the git-repo.md description entry to reflect the 2026-09-21T18:17Z fetch + the vault HEAD unchanged at `09bec367` for the 10th consecutive fetch + the wiki HEAD `d5a2b15` + the 40/35/35/28-day carry-forward bump + the **37th git-repo-1 fetch** of the 2026-08-07 streak + the 10-dirty-file baseline
  - **`/sources/README.md`** — refreshed Active connectors Git repo row + Connector roll Git repo row to mention the 2026-09-21T18:17Z fetch + the **thirty-eighth** consecutive sources-sync + the 10-dirty-file baseline + the 40/35/35/28-day carry-forward bump
 - Wiki edits: see the corresponding "Latest update — git-repo-1 (2026-09-21T18:17Z)" paragraph on `/quickstart.md` for the full delta list.
 ## Synthesis-policy — this run (2026-09-20T18:07Z)
 - **Vault delta: 0 new vault commits + 1 working-tree modification persisting** — vault HEAD unchanged at `09bec367` for the **9th consecutive fetch** after the Tomas 2026 + Vijakumaran 2026 resumption on 2026-09-11T18:14Z. **9 calendar days of vault silence** since the 2026-09-11 resumption (the 2026-09-19T18:04Z fetch recorded 8 calendar days; +1 calendar day from 2026-09-19 → 2026-09-20). The same MOC-file modification that surfaced at the 2026-09-13T18:08Z fetch (`M "04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md"`, mtime 2026-09-13 11:55:42 +0800) **persists uncommitted for 7 calendar days** at this fetch — Robin is editing the MOC index file but the modification has not been promoted to a commit. No new vault mtime changes were observed in the 2026-09-19T18:04Z → 2026-09-20T18:07Z 24-hour window. The 8 untracked regional agent files from 2026-08-07 (per the source-specific instruction "Track vault + OpenWiki wiki mtime + commits (Robin 8-07 added)") continue to carry forward unchanged: `02-Clients/Agents/全国经销商地图-2026-0807.md` (1310 bytes) + `02-Clients/Agents/华东-2026-0807.md` (10030 bytes) + `02-Clients/Agents/华北-2026-0807.md` (13057 bytes) + `02-Clients/Agents/华南-2026-0807.md` (10744 bytes) + `02-Clients/Agents/山东-2026-0807.md` (8592 bytes) + `02-Clients/Agents/湖北-2026-0807.md` (5766 bytes) + `02-Clients/Agents/西北-2026-0807.md` (2287 bytes) + `02-Clients/Agents/西南-2026-0807.md` (2657 bytes) — all dated 2026-08-07 20:24:19 +0800, documented in [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md).
 - **Wiki delta: automated maintenance only** (1 daily update + 1 sources-sync). The 2 new wiki commits in the 24-hour window are routine: `49e3f63` daily update 2026-09-20 + `95f286d` sources-sync 2026-09-20 — the **thirty-seventh** consecutive sources-sync (continuing the count-data wipe pattern that started at the 2026-08-15 `2507925` commit). The wiki HEAD bump `6e2a733` → `95f286d` covers 1 calendar day.
 - **Dirty-file baseline change**: 5-dirty baseline (at 2026-09-19T18:04Z) → **12-dirty baseline** (at 2026-09-20T18:07Z). The `49e3f63` daily update re-touched the standard 10-file cycle (`.last-update.json` + `sources/README.md` + `sources/git-repo.md` + `sources/hackernews.md` + `sources/index.md` + `sources/web-search.md` + `themes.md` + `themes/05-robin-research.md` + `themes/index.md` + `quickstart.md`); the `95f286d` sources-sync re-touched the 4 source-sync files (`sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md`); the CLI metadata cycle re-touched `sources/openwiki-version-drift.md` — net effect: the 4 source-sync files were re-dirtied by the sources-sync that landed after the daily update cleared them, +7 vs the 5-dirty baseline. The 12-dirty-file list at 2026-09-20T18:07Z: `M .last-update.json` + `M quickstart.md` + `M sources/README.md` + `M sources/hackernews.md` + `M sources/index.md` + `M sources/nocodb.md` + `M sources/openwiki-version-drift.md` + `M sources/ragflow.md` + `M sources/seafile.md` + `M sources/web-search.md` + `M sources/wikijs.md` + `M themes.md`.
 - **Carry-forward bump** to **39/34/34/27-day** at this fetch (highest carry-forward durations of the 2026-08-07 streak, +1 day from the 2026-09-19 fetch's 38/33/33/26-day): `Review/zhou2023_computer_vision_microfluidics.md` 38 → **39-day** (36 → **37 fetches silent**), `celvivo_commercial/` + `templates/` 33 → **34-day** (33 → **34 fetches silent** each), `deepread_40240593/` 26 → **27-day** (25 → **26 consecutive silent fetches** since creation; mtime unchanged at 2026-08-24 16:31 +0800).
 - **Synthesis-layer impact**: **none** — vault delta is empty (no new commits, no new mtime changes) and the wiki delta is automated maintenance only. The MOC-file working-tree modification persists uncommitted for 7 calendar days; it does not affect synthesis-layer pages until the commit lands. No `/themes.md` row, no `/commitments.md` row, no `/open-questions.md` row, no `/personal-logistics.md` item is added at this fetch.
  - **`/quickstart.md`** gets a new "Latest update — git-repo-1 (2026-09-20T18:07Z)" paragraph + the description frontmatter mentions the 2026-09-20T18:07Z git-repo-1 fetch + the **36th git-repo-1 fetch** of the 2026-08-07 streak + the **vault-silent-for-9th-consecutive-fetch** event + the 2 new wiki commits (36th/37th sources-sync sequence: `49e3f63` daily update + `95f286d` sources-sync thirty-seventh) + the 39/34/34/27-day carry-forward bump + the 12-dirty-file baseline + the MOC-file working-tree modification persisting uncommitted for 7 calendar days + the Robin 8-07 added untracked regional agent files
  - **`/sources/git-repo.md`** (this page) — description frontmatter refreshed to mention the 2026-09-20T18:07Z fetch; tags refreshed to add `2026-09-20`, `vault-silent-9d-consecutive-fetch`, `thirty-seventh-sources-sync-2026-09-20`, `thirty-sixth-git-repo-fetch-36th`, `wiki-2-new-commits`, `moc-organoid-3d-culture-uncommitted-edit-7d`, `deepread-40240593-twenty-seven-silent-fetches`, `robin-8-07-added-untracked-regional-agent-files`; timestamp refreshed to `2026-09-20T18:07:00Z`; Source-config vault/wiki HEADs refreshed; Latest-manifest section refreshed; Carry-forward table bumped to 39/34/34/27-day; Recent-commits-wiki table refreshed (2 new commits at top); this Synthesis-policy section added; Previous-run section updated
  - **`/themes/05-robin-research.md`** — frontmatter description refreshed to mention the 2026-09-20T18:07Z fetch + the vault HEAD unchanged for the 9th consecutive fetch + the 2 new wiki commits (36th/37th sources-sync sequence) + the 39/34/34/27-day carry-forward bump + the MOC-file working-tree modification persisting uncommitted for 7 calendar days; 04-Literature/Deep-Reads/ breakdown table refreshed with the 39/34/34/27-day carry-forward bump
  - **`/sources/index.md`** — refreshed the git-repo.md description entry to reflect the 2026-09-20T18:07Z fetch + the vault HEAD unchanged at `09bec367` for the 9th consecutive fetch + the wiki HEAD `95f286d` + the 39/34/34/27-day carry-forward bump + the **36th git-repo-1 fetch** of the 2026-08-07 streak + the 12-dirty-file baseline
  - **`/sources/README.md`** — refreshed Active connectors Git repo row + Connector roll Git repo row to mention the 2026-09-20T18:07Z fetch + the **thirty-seventh** consecutive sources-sync + the 12-dirty-file baseline + the 39/34/34/27-day carry-forward bump
 - Wiki edits: see the corresponding "Latest update — git-repo-1 (2026-09-20T18:07Z)" paragraph on `/quickstart.md` for the full delta list.
 ## Synthesis-policy — this run (2026-09-19T18:04Z)
 - **Vault delta: 0 new vault commits + 1 working-tree modification persisting** — vault HEAD unchanged at `09bec367` for the **8th consecutive fetch** after the Tomas 2026 + Vijakumaran 2026 resumption on 2026-09-11T18:14Z. **8 calendar days of vault silence** since the 2026-09-11 resumption (the 2026-09-18T18:15Z fetch recorded 7 calendar days; +1 calendar day from 2026-09-18 → 2026-09-19). The same MOC-file modification that surfaced at the 2026-09-13T18:08Z fetch (`M "04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md"`, mtime 2026-09-13 11:55:42 +0800) **persists uncommitted for 6 calendar days** at this fetch — Robin is editing the MOC index file but the modification has not been promoted to a commit. No new vault mtime changes were observed in the 2026-09-18T18:15Z → 2026-09-19T18:04Z 24-hour window. The 8 untracked regional agent files from 2026-08-07 (per the source-specific instruction "Track vault + OpenWiki wiki mtime + commits (Robin 8-07 added)") continue to carry forward unchanged: `02-Clients/Agents/全国经销商地图-2026-0807.md` (1310 bytes) + `02-Clients/Agents/华东-2026-0807.md` (10030 bytes) + `02-Clients/Agents/华北-2026-0807.md` (13057 bytes) + `02-Clients/Agents/华南-2026-0807.md` (10744 bytes) + `02-Clients/Agents/山东-2026-0807.md` (8592 bytes) + `02-Clients/Agents/湖北-2026-0807.md` (5766 bytes) + `02-Clients/Agents/西北-2026-0807.md` (2287 bytes) + `02-Clients/Agents/西南-2026-0807.md` (2657 bytes) — all dated 2026-08-07 20:24:19 +0800, documented in [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md).
 - **Wiki delta: automated maintenance only** (1 daily update + 1 sources-sync). The 2 new wiki commits in the 24-hour window are routine: `1ba0fb1` sources-sync 2026-09-19 — the **thirty-sixth** consecutive sources-sync — + `6e2a733` daily update 2026-09-19 (continuing the count-data wipe pattern that started at the 2026-08-15 `2507925` commit). The wiki HEAD bump `c6e81a5` → `6e2a733` covers 1 calendar day. The `6e2a733` daily update commit re-touched 15 files (the standard cycle) including `themes/05-robin-research.md` + `sources/git-repo.md` + all 4 source-sync files; the `1ba0fb1` sources-sync re-touched `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md`.
 - **Dirty-file baseline change**: 11-dirty baseline (at 2026-09-18T18:15Z) → **5-dirty baseline** (at 2026-09-19T18:04Z). The `6e2a733` daily update commit cleared the prior 11-dirty-file baseline — `index.md` + `quickstart.md` + `sources/literature.md` + `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md` + `sources/README.md` + `themes/05-robin-research.md` + `themes/index.md` + `sources/git-repo.md` were all staged+committed — then 5 files were re-touched in the working tree by the post-commit synthesis pipeline (likely `.last-update.json` from the CLI metadata cycle + `sources/hackernews.md` from the hackernews-1 connector daily update + `sources/web-search.md` from the web-search connector daily update + `themes.md` from the synthesis layer + `sources/index.md` from the sources index synthesis). The 5-dirty-file list at 2026-09-19T18:04Z: `M .last-update.json` + `M sources/hackernews.md` + `M sources/index.md` + `M sources/web-search.md` + `M themes.md`.
 - **Carry-forward bump** to **38/33/33/26-day** at this fetch (highest carry-forward durations of the 2026-08-07 streak, +1 day from the 2026-09-18 fetch's 37/32/32/25-day): `Review/zhou2023_computer_vision_microfluidics.md` 37 → **38-day** (35 → **36 fetches silent**), `celvivo_commercial/` + `templates/` 32 → **33-day** (32 → **33 fetches silent** each), `deepread_40240593/` 25 → **26-day** (24 → **25 consecutive silent fetches** since creation; mtime unchanged at 2026-08-24 16:31 +0800).
 - **Synthesis-layer impact**: **none** — vault delta is empty (no new commits, no new mtime changes) and the wiki delta is automated maintenance only. The MOC-file working-tree modification persists uncommitted for 6 calendar days; it does not affect synthesis-layer pages until the commit lands. No `/themes.md` row, no `/commitments.md` row, no `/open-questions.md` row, no `/personal-logistics.md` item is added at this fetch.
  - **`/quickstart.md`** gets a new "Latest update — git-repo-1 (2026-09-19T18:04Z)" paragraph + the description frontmatter mentions the 2026-09-19T18:04Z git-repo-1 fetch + the **35th git-repo-1 fetch** of the 2026-08-07 streak + the **vault-silent-for-8th-consecutive-fetch** event + the 2 new wiki commits (35th/36th sources-sync sequence: `1ba0fb1` sources-sync thirty-sixth + `6e2a733` daily update) + the 38/33/33/26-day carry-forward bump + the 5-dirty-file baseline + the MOC-file working-tree modification persisting uncommitted for 6 calendar days + the Robin 8-07 added untracked regional agent files
  - **`/sources/git-repo.md`** (this page) — description frontmatter refreshed to mention the 2026-09-19T18:04Z fetch; tags refreshed to add `2026-09-19`, `vault-silent-8d-consecutive-fetch`, `thirty-sixth-sources-sync-2026-09-19`, `thirty-fifth-git-repo-fetch-35th`, `wiki-2-new-commits`, `moc-organoid-3d-culture-uncommitted-edit-6d`, `deepread-40240593-twenty-six-silent-fetches`, `robin-8-07-added-untracked-regional-agent-files`; timestamp refreshed to `2026-09-19T18:04:00Z`; Source-config vault/wiki HEADs refreshed; Latest-manifest section refreshed; Carry-forward table bumped to 38/33/33/26-day; Recent-commits-wiki table refreshed (2 new commits at top); this Synthesis-policy section added; Previous-run section updated
  - **`/themes/05-robin-research.md`** — frontmatter description refreshed to mention the 2026-09-19T18:04Z fetch + the vault HEAD unchanged for the 8th consecutive fetch + the 2 new wiki commits (35th/36th sources-sync sequence) + the 38/33/33/26-day carry-forward bump + the MOC-file working-tree modification persisting uncommitted for 6 calendar days; 04-Literature/Deep-Reads/ breakdown table refreshed with the 38/33/33/26-day carry-forward bump
  - **`/sources/index.md`** — refreshed the git-repo.md description entry to reflect the 2026-09-19T18:04Z fetch + the vault HEAD unchanged at `09bec367` for the 8th consecutive fetch + the wiki HEAD `6e2a733` + the 38/33/33/26-day carry-forward bump + the **35th git-repo-1 fetch** of the 2026-08-07 streak + the 5-dirty-file baseline
  - **`/sources/README.md`** — refreshed Active connectors Git repo row + Connector roll Git repo row to mention the 2026-09-19T18:04Z fetch + the **thirty-sixth** consecutive sources-sync + the 5-dirty-file baseline + the 38/33/33/26-day carry-forward bump
 - Wiki edits: see the corresponding "Latest update — git-repo-1 (2026-09-19T18:04Z)" paragraph on `/quickstart.md` for the full delta list.
 ## Synthesis-policy — this run (2026-09-18T18:15Z)
 - **Vault delta: 0 new vault commits + 1 working-tree modification persisting** — vault HEAD unchanged at `09bec367` for the **7th consecutive fetch** after the Tomas 2026 + Vijakumaran 2026 resumption on 2026-09-11T18:14Z. **7 calendar days of vault silence** since the 2026-09-11 resumption (the 2026-09-17T18:22Z fetch recorded 6 calendar days; +1 calendar day from 2026-09-17 → 2026-09-18). The same MOC-file modification that surfaced at the 2026-09-13T18:08Z fetch (`M "04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md"`, mtime 2026-09-13 11:55:42 +0800) **persists uncommitted for 5 calendar days** at this fetch — Robin is editing the MOC index file but the modification has not been promoted to a commit. No new vault mtime changes were observed in the 2026-09-17T18:22Z → 2026-09-18T18:15Z 24-hour window. The 8 untracked regional agent files from 2026-08-07 (per the source-specific instruction "Track vault + OpenWiki wiki mtime + commits (Robin 8-07 added)") continue to carry forward unchanged: `02-Clients/Agents/全国经销商地图-2026-0807.md` (1310 bytes) + `02-Clients/Agents/华东-2026-0807.md` (10030 bytes) + `02-Clients/Agents/华北-2026-0807.md` (13057 bytes) + `02-Clients/Agents/华南-2026-0807.md` (10744 bytes) + `02-Clients/Agents/山东-2026-0807.md` (8592 bytes) + `02-Clients/Agents/湖北-2026-0807.md` (5766 bytes) + `02-Clients/Agents/西北-2026-0807.md` (2287 bytes) + `02-Clients/Agents/西南-2026-0807.md` (2657 bytes) — all dated 2026-08-07 20:24:19 +0800, documented in [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md).
 - **Wiki delta: automated maintenance only** (1 daily update + 1 sources-sync). The 2 new wiki commits in the 24-hour window are routine: `46a508d` daily update 2026-09-18 + `c6e81a5` sources-sync 2026-09-18 — the **thirty-fifth** consecutive sources-sync (continuing the count-data wipe pattern that started at the 2026-08-15 `2507925` commit). The wiki HEAD bump `307e038` → `c6e81a5` covers 1 calendar day.
 - **Dirty-file baseline change**: 10-dirty baseline (at 2026-09-17T18:22Z) → **11-dirty baseline** (at 2026-09-18T18:15Z). The `46a508d` daily update re-touched the same synthesis-layer files; `sources/index.md` was newly re-touched this run (not in the 10-dirty list at 2026-09-17 — likely a re-touch from the synthesis-side write path); the `c6e81a5` sources-sync re-touched the 4 source-sync files (`sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md`); `sources/README.md` was cleared from the dirty list (it had been in the 10-dirty list at 2026-09-17 because the daily update at that fetch re-touched it). The 11-dirty-file list at 2026-09-18T18:15Z: `M .last-update.json` + `M index.md` + `M quickstart.md` + `M sources/hackernews.md` + `M sources/index.md` + `M sources/literature.md` + `M sources/nocodb.md` + `M sources/ragflow.md` + `M sources/seafile.md` + `M sources/web-search.md` + `M sources/wikijs.md` + `M themes.md`.
 - **Carry-forward bump** to **37/32/32/25-day** at this fetch (highest carry-forward durations of the 2026-08-07 streak, +1 day from the 2026-09-17 fetch's 36/31/31/24-day): `Review/zhou2023_computer_vision_microfluidics.md` 36 → **37-day** (34 → **35 fetches silent**), `celvivo_commercial/` + `templates/` 31 → **32-day** (31 → **32 fetches silent** each), `deepread_40240593/` 24 → **25-day** (23 → **24 consecutive silent fetches** since creation; mtime unchanged at 2026-08-24 16:31 +0800).
 - **Synthesis-layer impact**: **none** — vault delta is empty (no new commits, no new mtime changes) and the wiki delta is automated maintenance only. The MOC-file working-tree modification persists uncommitted for 5 calendar days; it does not affect synthesis-layer pages until the commit lands. No `/themes.md` row, no `/commitments.md` row, no `/open-questions.md` row, no `/personal-logistics.md` item is added at this fetch.
  - **`/quickstart.md`** gets a new "Latest update — git-repo-1 (2026-09-18T18:15Z)" paragraph + the description frontmatter mentions the 2026-09-18T18:15Z git-repo-1 fetch + the **34th git-repo-1 fetch** of the 2026-08-07 streak + the **vault-silent-for-7th-consecutive-fetch** event + the 2 new wiki commits (34th/35th sources-sync sequence: `46a508d` daily update + `c6e81a5` sources-sync thirty-fifth) + the 37/32/32/25-day carry-forward bump + the 11-dirty-file baseline + the MOC-file working-tree modification persisting uncommitted for 5 calendar days + the Robin 8-07 added untracked regional agent files
  - **`/sources/git-repo.md`** (this page) — description frontmatter refreshed to mention the 2026-09-18T18:15Z fetch; tags refreshed to add `2026-09-18`, `vault-silent-9d`, `thirty-fifth-sources-sync`, `thirty-fourth-git-repo-fetch`, `wiki-2-new-commits`, `moc-organoid-3d-culture-uncommitted-edit-5d`, `deepread-40240593-twenty-five-silent-fetches`, `robin-8-07-added-untracked-regional-agent-files`; timestamp refreshed to `2026-09-18T18:15:00Z`; Source-config vault/wiki HEADs refreshed; Latest-manifest section refreshed; Carry-forward table bumped to 37/32/32/25-day; Recent-commits-wiki table refreshed (2 new commits at top); this Synthesis-policy section added; Previous-run section updated
  - **`/themes/05-robin-research.md`** — frontmatter description refreshed to mention the 2026-09-18T18:15Z fetch + the vault HEAD unchanged for the 7th consecutive fetch + the 2 new wiki commits (34th/35th sources-sync sequence) + the 37/32/32/25-day carry-forward bump + the MOC-file working-tree modification persisting uncommitted for 5 calendar days; 04-Literature/Deep-Reads/ breakdown table refreshed with the 37/32/32/25-day carry-forward bump
  - **`/sources/index.md`** — refreshed the git-repo.md description entry to reflect the 2026-09-18T18:15Z fetch + the vault HEAD unchanged at `09bec367` for the 7th consecutive fetch + the wiki HEAD `c6e81a5` + the 37/32/32/25-day carry-forward bump + the **34th git-repo-1 fetch** of the 2026-08-07 streak + the 11-dirty-file baseline
  - **`/sources/README.md`** — refreshed Active connectors Git repo row + Connector roll Git repo row to mention the 2026-09-18T18:15Z fetch + the **thirty-fifth** consecutive sources-sync + the 11-dirty-file baseline + the 37/32/32/25-day carry-forward bump
 - Wiki edits: see the corresponding "Latest update — git-repo-1 (2026-09-18T18:15Z)" paragraph on `/quickstart.md` for the full delta list.
 ## Synthesis-policy — this run (2026-09-17T18:22Z)
 - **Vault delta: 0 new vault commits + 1 working-tree modification persisting** — vault HEAD unchanged at `09bec367` for the **6th consecutive fetch** after the Tomas 2026 + Vijakumaran 2026 resumption on 2026-09-11T18:14Z. **6 calendar days of vault silence** since the 2026-09-11 resumption (the 2026-09-16T18:18Z fetch recorded 5 calendar days; +1 calendar day from 2026-09-16 → 2026-09-17). The same MOC-file modification that surfaced at the 2026-09-13T18:08Z fetch (`M "04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md"`, mtime 2026-09-13 11:55:42 +0800) **persists uncommitted for 4 calendar days** at this fetch — Robin is editing the MOC index file but the modification has not been promoted to a commit. No new vault mtime changes were observed in the 2026-09-16T18:18Z → 2026-09-17T18:22Z 24-hour window. The 8 untracked regional agent files from 2026-08-07 (per the source-specific instruction "Track vault + OpenWiki wiki mtime + commits (Robin 8-07 added)") continue to carry forward unchanged: `02-Clients/Agents/全国经销商地图-2026-0807.md` (1310 bytes) + `02-Clients/Agents/华东-2026-0807.md` (10030 bytes) + `02-Clients/Agents/华北-2026-0807.md` (13057 bytes) + `02-Clients/Agents/华南-2026-0807.md` (10744 bytes) + `02-Clients/Agents/山东-2026-0807.md` (8592 bytes) + `02-Clients/Agents/湖北-2026-0807.md` (5766 bytes) + `02-Clients/Agents/西北-2026-0807.md` (2287 bytes) + `02-Clients/Agents/西南-2026-0807.md` (2657 bytes) — all dated 2026-08-07 20:24:19 +0800, documented in [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md).
 - **Wiki delta: automated maintenance only** (1 daily update + 1 sources-sync). The 2 new wiki commits in the 24-hour window are routine: `3d95e56` daily update 2026-09-17 + `307e038` sources-sync 2026-09-17 — the **thirty-fourth** consecutive sources-sync (continuing the count-data wipe pattern that started at the 2026-08-15 `2507925` commit). The wiki HEAD bump `ac46732` → `307e038` covers 1 calendar day.
 - **Dirty-file baseline change**: 11-dirty baseline (at 2026-09-16T18:18Z) → **10-dirty baseline** (at 2026-09-17T18:22Z). The `3d95e56` daily update cleared `index.md` + `sources/README.md` that were dirty at the prior fetch; `sources/literature.md` was newly re-touched this run (not previously in the 11-dirty list — likely a re-touch from the synthesis-side write path); the `307e038` sources-sync re-touched the 4 source-sync files (`sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md`). The 10-dirty-file list at 2026-09-17T18:22Z: `M .last-update.json` + `M quickstart.md` + `M sources/hackernews.md` + `M sources/literature.md` + `M sources/nocodb.md` + `M sources/ragflow.md` + `M sources/seafile.md` + `M sources/web-search.md` + `M sources/wikijs.md` + `M themes.md`.
 - **Carry-forward bump** to **36/31/31/24-day** at this fetch (highest carry-forward durations of the 2026-08-07 streak, +1 day from the 2026-09-16 fetch's 35/30/30/23-day): `Review/zhou2023_computer_vision_microfluidics.md` 35 → **36-day** (33 → **34 fetches silent**), `celvivo_commercial/` + `templates/` 30 → **31-day** (30 → **31 fetches silent** each), `deepread_40240593/` 23 → **24-day** (22 → **23 consecutive silent fetches** since creation; mtime unchanged at 2026-08-24 16:31 +0800).
 - **Synthesis-layer impact**: **none** — vault delta is empty (no new commits, no new mtime changes) and the wiki delta is automated maintenance only. The MOC-file working-tree modification persists uncommitted for 4 calendar days; it does not affect synthesis-layer pages until the commit lands. No `/themes.md` row, no `/commitments.md` row, no `/open-questions.md` row, no `/personal-logistics.md` item is added at this fetch.
  - **`/quickstart.md`** gets a new "Latest update — git-repo-1 (2026-09-17T18:22Z)" paragraph + the description frontmatter mentions the 2026-09-17T18:22Z git-repo-1 fetch + the **33rd git-repo-1 fetch** of the 2026-08-07 streak + the **vault-silent-for-6th-consecutive-fetch** event + the 2 new wiki commits (33rd/34th sources-sync sequence: `3d95e56` daily update + `307e038` sources-sync thirty-fourth) + the 36/31/31/24-day carry-forward bump + the 10-dirty-file baseline + the MOC-file working-tree modification persisting uncommitted for 4 calendar days + the Robin 8-07 added untracked regional agent files
  - **`/sources/git-repo.md`** (this page) — description frontmatter refreshed to mention the 2026-09-17T18:22Z fetch; tags refreshed to add `2026-09-17`, `vault-silent-8d`, `thirty-fourth-sources-sync`, `thirty-third-git-repo-fetch`, `wiki-2-new-commits`, `moc-organoid-3d-culture-uncommitted-edit-4d`, `deepread-40240593-twenty-four-silent-fetches`, `robin-8-07-added-untracked-regional-agent-files`; timestamp refreshed to `2026-09-17T18:22:00Z`; Source-config vault/wiki HEADs refreshed; Latest-manifest section refreshed; Carry-forward table bumped to 36/31/31/24-day; Recent-commits-wiki table refreshed (2 new commits at top); this Synthesis-policy section added; Previous-run section updated
  - **`/themes/05-robin-research.md`** — frontmatter description refreshed to mention the 2026-09-17T18:22Z fetch + the vault HEAD unchanged for the 6th consecutive fetch + the 2 new wiki commits (33rd/34th sources-sync sequence) + the 36/31/31/24-day carry-forward bump + the MOC-file working-tree modification persisting uncommitted for 4 calendar days; 04-Literature/Deep-Reads/ breakdown table refreshed with the 36/31/31/24-day carry-forward bump
  - **`/sources/index.md`** — refreshed the git-repo.md description entry to reflect the 2026-09-17T18:22Z fetch + the vault HEAD unchanged at `09bec367` for the 6th consecutive fetch + the wiki HEAD `307e038` + the 36/31/31/24-day carry-forward bump + the **33rd git-repo-1 fetch** of the 2026-08-07 streak + the 10-dirty-file baseline
  - **`/sources/README.md`** — refreshed Active connectors Git repo row + Connector roll Git repo row to mention the 2026-09-17T18:22Z fetch + the **thirty-fourth** consecutive sources-sync + the 10-dirty-file baseline + the 36/31/31/24-day carry-forward bump
 - Wiki edits: see the corresponding "Latest update — git-repo-1 (2026-09-17T18:22Z)" paragraph on `/quickstart.md` for the full delta list.
 ## Synthesis-policy — this run (2026-09-16T18:18Z)
 - **Vault delta: 0 new vault commits + 1 working-tree modification persisting** — vault HEAD unchanged at `09bec367` for the **5th consecutive fetch** after the Tomas 2026 + Vijakumaran 2026 resumption on 2026-09-11T18:14Z. **5 calendar days of vault silence** since the 2026-09-11 resumption. The same MOC-file modification that surfaced at the 2026-09-13T18:08Z fetch (`M "04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md"`, mtime 2026-09-13 11:55:42 +0800) **persists uncommitted for 3 calendar days** at this fetch — Robin is editing the MOC index file but the modification has not been promoted to a commit. No new vault mtime changes were observed in the 2026-09-13T18:08Z → 2026-09-16T18:18Z 72-hour window. The 8 untracked regional agent files from 2026-08-07 carry forward unchanged.
 - **Wiki delta: automated maintenance only** (3 daily updates + 3 sources-syncs). The 6 new wiki commits in the 72-hour window are routine: `667730f` daily update 2026-09-14 + `09f47d6` sources-sync 2026-09-14 thirty-first + `f38cebf` daily update 2026-09-15 + `f5465f9` sources-sync 2026-09-15 thirty-second + `73dae5e` daily update 2026-09-16 + `ac46732` sources-sync 2026-09-16 thirty-third. The wiki HEAD bump `5f33bd3` → `ac46732` covers 3 calendar days.
 - **Dirty-file baseline change**: 8-dirty baseline (at 2026-09-13T18:08Z) → **11-dirty baseline** (at 2026-09-16T18:18Z). The 3 daily-update cycles re-touched `index.md` + `quickstart.md` + `themes.md` (the 2026-09-13 daily update had cleared them); the 3 sources-syncs re-touched the 4 source-sync files (`sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md`) each cycle. The 11-dirty-file list at 2026-09-16T18:18Z: `M .last-update.json` + `M index.md` + `M quickstart.md` + `M sources/README.md` + `M sources/hackernews.md` + `M sources/nocodb.md` + `M sources/ragflow.md` + `M sources/seafile.md` + `M sources/web-search.md` + `M sources/wikijs.md` + `M themes.md`.
 - **Carry-forward bump** to **35/30/30/23-day** at this fetch (highest carry-forward durations of the 2026-08-07 streak): `Review/zhou2023_computer_vision_microfluidics.md` 32 → **35-day** (33 fetches silent), `celvivo_commercial/` + `templates/` 27 → **30-day** (30 fetches silent each), `deepread_40240593/` 20 → **23-day** (22 consecutive silent fetches since creation; mtime unchanged at 2026-08-24 16:31 +0800).
 - **Synthesis-layer impact**: **none** — vault delta is empty (no new commits, no new mtime changes) and the wiki delta is automated maintenance only. The MOC-file working-tree modification persists uncommitted for 3 calendar days; it does not affect synthesis-layer pages until the commit lands. No `/themes.md` row, no `/commitments.md` row, no `/open-questions.md` row, no `/personal-logistics.md` item is added at this fetch.
  - **`/quickstart.md`** gets a new "Latest update — git-repo-1 (2026-09-16T18:18Z)" paragraph + the description frontmatter mentions the 2026-09-16T18:18Z git-repo-1 fetch + the **32nd git-repo-1 fetch** of the 2026-08-07 streak + the **vault-silent-for-5th-consecutive-fetch** event + the 6 new wiki commits (31st/32nd/33rd sources-sync sequence) + the 35/30/30/23-day carry-forward bump + the 11-dirty-file baseline + the MOC-file working-tree modification persisting uncommitted for 3 calendar days
  - **`/sources/git-repo.md`** (this page) — description frontmatter refreshed to mention the 2026-09-16T18:18Z fetch; tags refreshed to add `2026-09-16`, `2026-09-15`, `2026-09-14`, `vault-silent-5d`, `vault-silent-6d`, `vault-silent-7d`, `moc-organoid-3d-culture-uncommitted-edit-3d`, `vault-working-tree-moc-modification-2026-09-13-persists`, `thirty-first-sources-sync`, `thirty-second-sources-sync`, `thirty-third-sources-sync`, `thirty-second-git-repo-fetch`, `wiki-6-new-commits`, `deepread-40240593-twenty-two-silent-fetches`, `deepread-40240593-twenty-three-silent-fetches`; timestamp refreshed to `2026-09-16T18:18:00Z`; Source-config vault/wiki HEADs refreshed; Latest-manifest section refreshed; Carry-forward table bumped to 35/30/30/23-day; Recent-commits-wiki table refreshed (6 new commits at top); this Synthesis-policy section added; Previous-run section updated
  - **`/themes/05-robin-research.md`** — frontmatter description refreshed to mention the 2026-09-16T18:18Z fetch + the vault HEAD unchanged for the 5th consecutive fetch + the 6 new wiki commits (31st/32nd/33rd sources-sync sequence) + the 35/30/30/23-day carry-forward bump + the MOC-file working-tree modification persisting uncommitted; 04-Literature/Deep-Reads/ breakdown table refreshed with the 35/30/30/23-day carry-forward bump
  - **`/sources/index.md`** — refreshed the git-repo.md description entry to reflect the 2026-09-16T18:18Z fetch + the vault HEAD unchanged at `09bec367` for the 5th consecutive fetch + the wiki HEAD `ac46732` + the 35/30/30/23-day carry-forward bump + the **32nd git-repo-1 fetch** of the 2026-08-07 streak + the 11-dirty-file baseline
  - **`/sources/README.md`** — refreshed Active connectors Git repo row + Connector roll Git repo row to mention the 2026-09-16T18:18Z fetch + the **thirty-third** consecutive sources-sync + the 11-dirty-file baseline + the 35/30/30/23-day carry-forward bump
 - Wiki edits: see the corresponding "Latest update — git-repo-1 (2026-09-16T18:18Z)" paragraph on `/quickstart.md` for the full delta list.
 ## Synthesis-policy — this run (2026-09-13T18:08Z)
 - **Vault delta: 0 new vault commits + 1 working-tree modification** — vault HEAD unchanged at `09bec367` (the 2nd consecutive vault-silent fetch after the Tomas 2026 + Vijakumaran 2026 resumption). The only vault change is the MOC-file edit: `M "04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md"` (mtime 2026-09-13 11:55:42 +0800) — Robin is actively editing the MOC index file but has not yet committed. This is the first vault working-tree modification since the 2026-08-24/25 burst (the 2026-08-31 cluster was an in-vault commit, not an uncommitted edit), and it routes through the MOC-folder rather than the `deepread_<slug>/` working-folder pipeline that the 2026-08-24/25 burst had hypothesized. The `deepread_40240593/` working folder is still silent (mtime unchanged across 19 consecutive silent fetches since the 2026-08-24 16:31 +0800 baseline).
 - **Wiki delta: automated maintenance only** (CLI metadata cycle + sources-sync + daily update + sources-sync). The 4 new wiki commits in the 48-hour window are routine: 2 daily updates (`999a37d` + `0447186`) + 2 sources-syncs (`7cfb801` twenty-ninth + `5f33bd3` thirtieth). The wiki HEAD bump `55d930f` → `5f33bd3` covers 2 calendar days.
 - **Dirty-file baseline change**: 10-dirty baseline (at 2026-09-11T18:14Z) → **8-dirty baseline** (at 2026-09-13T18:08Z). Different shape: `index.md` + `quickstart.md` + `sources/git-repo.md` + `themes.md` were cleared by the `999a37d` daily update; new `M sources/openwiki-version-drift.md` appeared. The 8-dirty-file list at 2026-09-13T18:08Z: `M .last-update.json` + `M sources/hackernews.md` + `M sources/nocodb.md` + `M sources/openwiki-version-drift.md` + `M sources/ragflow.md` + `M sources/seafile.md` + `M sources/web-search.md` + `M sources/wikijs.md`.
 - **Synthesis-layer impact**: **none** — vault delta is empty (no new commits, no new mtime changes that alter the synthesis-layer shape) and the wiki delta is automated maintenance only. The MOC-file working-tree edit is uncommitted; it does not affect synthesis-layer pages until the commit lands. No `/themes.md` row, no `/commitments.md` row, no `/open-questions.md` row, no `/personal-logistics.md` item is added at this fetch.
  - **`/quickstart.md`** gets a new "Latest update — git-repo-1 (2026-09-13T18:08Z)" paragraph + the description frontmatter mentions the 2026-09-13T18:08Z git-repo-1 fetch + the vault-unchanged state + the 4 new wiki commits (28th/29th/30th sources-sync sequence) + the 32/27/27/20-day carry-forward bump + the 8-dirty-file baseline + the MOC-file working-tree modification
  - **`/sources/git-repo.md`** (this page) — description frontmatter refreshed to mention the 2026-09-13T18:08Z fetch; tags refreshed to add `2026-09-13`, `2026-09-12`, `twenty-ninth-sources-sync`, `thirtieth-sources-sync`, `thirtieth-git-repo-fetch`, `thirty-first-git-repo-fetch`, `deepread-40240593-twenty-silent-fetches`, `moc-organoid-3d-culture-uncommitted-edits`, `vault-working-tree-moc-modification-2026-09-13`; timestamp refreshed to `2026-09-13T18:08:00Z`; Source-config vault/wiki HEADs refreshed; Latest-manifest section refreshed; Carry-forward table bumped to 32/27/27/20-day; Recent-commits-wiki table refreshed (4 new commits at top); this Synthesis-policy section added; Previous-run section updated
  - **`/themes/05-robin-research.md`** — frontmatter description refreshed to mention the 2026-09-13T18:08Z fetch + the vault HEAD unchanged + the 4 new wiki commits + the 32/27/27/20-day carry-forward bump + the MOC-file working-tree modification; 04-Literature/Deep-Reads/ breakdown table refreshed with the 32/27/27/20-day carry-forward bump
  - **`/sources/index.md`** — refreshed the git-repo.md description entry to reflect the 2026-09-13T18:08Z fetch + the vault HEAD unchanged + the 4 new wiki commits (28th/29th/30th sources-sync) + the 32/27/27/20-day carry-forward bump + the **31st git-repo-1 fetch** of the 2026-08-07 streak + the 8-dirty-file baseline
  - **`/sources/README.md`** — refreshed Active connectors Git repo row + Connector roll Git repo row to mention the 2026-09-13T18:08Z fetch + the **thirtieth** consecutive sources-sync + the 8-dirty-file baseline + the 32/27/27/20-day carry-forward bump
 - Wiki edits: see the corresponding "Latest update — git-repo-1 (2026-09-13T18:08Z)" paragraph on `/quickstart.md` for the full delta list.
 ## Synthesis-policy — this run (2026-09-11T18:14Z)
 - **Vault delta: 2 new vault commits** (Tomas 2026 + Vijakumaran 2026) — vault silence streak BROKEN after 11 calendar days since the 2026-08-31 THIRD consecutive 5-paper CelVivo LDR cluster. Both new papers route through the standard `04-Literature/Deep-Reads/<application-domain>/<DOI>.md` pattern. The **v4 Flywheel auto-sink pipeline** (visible in the `09bec367` commit message "飞轮 v4 自动 sink") is the first observation of Robin's LDR pipeline v4 in action — the v3 SOP was 9 steps (per the 2026-08-25 `9aa2af4c` vendor-mapping retrofit); the v4 auto-sink iterates the SOP with an automated commit/sink step.
 - **Wiki delta: automated maintenance only** (CLI metadata cycle + sources-sync + daily update + sources-sync). The 4 new wiki commits are routine: 2 daily updates + 2 sources-syncs (the standard cadence).
 - **Synthesis-layer impact**:
  - **Vault silence streak BROKEN** — flips the narrative from "11 calendar days of vault silence" to "vault resumed after 11-day pause" + "2 new vault commits since the 2026-08-31 cluster" + "v4 Flywheel auto-sink pipeline first observation"
  - **`/sources/literature.md`** gets a new `2026-09-11 (Vijakumaran 2026 brain-organoid ALI oxygen engineering — first v4 Flywheel auto-sink entry)` row; the Tomas 2026 entry was added in a prior run (2026-09-10 row already present)
  - **`/themes.md`** `class-organoid-3d-bioprinting` row gets Last-seen refresh `2026-08-25` → `2026-09-11` + Evidence count bump `37+` → `39+` (Tomas 2026 + Vijakumaran 2026 = 2 new entries)
  - **`/themes/05-robin-research.md`** vault-snapshot metadata refreshed + 04-Literature/Deep-Reads/ breakdown table updated with Vijakumaran 2026 row + the 4 carry-forward untracked directories bumped to 30/25/25/18-day carry-forward
  - **`/quickstart.md`** gets a new "Latest update — git-repo-1 (2026-09-11T18:14Z)" paragraph + the description frontmatter mentions the 2026-09-11T18:14Z git-repo-1 fetch + the vault silence streak broken + the 2 new vault commits + the 4 new wiki commits + the 30/25/25/18-day carry-forward bump
  - **`/sources/index.md`** + **`/sources/README.md`** get their git-repo.md description entries refreshed
 - Wiki edits: see the corresponding "Latest update — git-repo-1 (2026-09-11T18:14Z)" paragraph on `/quickstart.md` for the full delta list.
 ## Previous run
 - 2026-09-30T18:24Z — vault HEAD unchanged at `09bec367` for the 19th consecutive fetch after the Tomas 2026 + Vijakumaran 2026 resumption, 0 new vault commits + 1 working-tree modification at `MOCs/MOC-类器官与3D培养.md` (mtime 2026-09-13 11:55:42 +0800, persists uncommitted for 17 calendar days at this fetch), 2 new wiki commits (`5c788cc` daily update 2026-09-30 + `1d3c470` sources-sync 2026-09-30 — the **forty-seventh** consecutive sources-sync), 11-dirty-file baseline (down from 13-dirty at the 2026-09-29T18:14Z fetch — the `5c788cc` daily update cleared `sources/git-repo.md` + `sources/README.md` + `sources/literature.md` + the `tmp/check_themes.py` deletion from the dirty list while the `1d3c470` sources-sync + post-commit write path re-touched `themes.md`; net: −2 vs the 13-dirty baseline), carry-forward bump to 49/44/44/37-day. See the "Synthesis-policy — this run (2026-09-30T18:24Z)" section above + the "Latest update — git-repo-1 (2026-09-30T18:24Z)" paragraph on `/quickstart.md` for the full synthesis of that run.
 - 2026-09-29T18:14Z — vault HEAD unchanged at `09bec367` for the 18th consecutive fetch after the Tomas 2026 + Vijakumaran 2026 resumption, 0 new vault commits + 1 working-tree modification at `MOCs/MOC-类器官与3D培养.md` (mtime 2026-09-13 11:55:42 +0800, persists uncommitted for 16 calendar days at this fetch), 2 new wiki commits (`92874d2` daily update 2026-09-29 + `2fccbf0` sources-sync 2026-09-29 — the **forty-sixth** consecutive sources-sync), 13-dirty-file baseline (vs the 12-dirty baseline at the 2026-09-28T18:09Z fetch — the `92874d2` daily update cleared `themes.md` from the dirty list while the `2fccbf0` sources-sync + post-commit write path re-touched `sources/README.md` + `sources/literature.md` + the `tmp/check_themes.py` deletion that the daily update committed remained in the dirty list; net: +1 vs the 12-dirty baseline), carry-forward bump to 48/43/43/36-day. See the "Synthesis-policy — this run (2026-09-29T18:14Z)" section above + the "Latest update — git-repo-1 (2026-09-29T18:14Z)" paragraph on `/quickstart.md` for the full synthesis of that run.
 - 2026-09-26T18:09Z — vault HEAD unchanged at `09bec367` for the 15th consecutive fetch after the Tomas 2026 + Vijakumaran 2026 resumption, 0 new vault commits + 1 working-tree modification at `MOCs/MOC-类器官与3D培养.md` (mtime 2026-09-13 11:55:42 +0800, persists uncommitted for 13 calendar days at this fetch), 2 new wiki commits (`41347af` daily update 2026-09-26 + `4becee0` sources-sync 2026-09-26 — the **forty-third** consecutive sources-sync), 11-dirty-file baseline (down from 12-dirty at the 2026-09-25T18:17Z fetch — the `41347af` daily update cleared `sources/README.md` from the dirty list; net: −1 vs the 12-dirty baseline), carry-forward bump to 45/40/40/33-day. See the "Synthesis-policy — this run (2026-09-26T18:09Z)" section above + the "Latest update — git-repo-1 (2026-09-26T18:09Z)" paragraph on `/quickstart.md` for the full synthesis of that run.
 - 2026-09-27T18:19Z — vault HEAD unchanged at `09bec367` for the 16th consecutive fetch after the Tomas 2026 + Vijakumaran 2026 resumption, 0 new vault commits + 1 working-tree modification at `MOCs/MOC-类器官与3D培养.md` (mtime 2026-09-13 11:55:42 +0800, persists uncommitted for 14 calendar days at this fetch), 2 new wiki commits (`3e52ff2` daily update 2026-09-27 + `057a35e` sources-sync 2026-09-27 — the **forty-fourth** consecutive sources-sync), 12-dirty-file baseline (up from 11-dirty at the 2026-09-26T18:09Z fetch — the `057a35e` sources-sync re-touched the 4 source-sync files; net: +1 vs the 11-dirty baseline), carry-forward bump to 46/41/41/34-day. See the "Synthesis-policy — this run (2026-09-27T18:19Z)" section above + the "Latest update — git-repo-1 (2026-09-27T18:19Z)" paragraph on `/quickstart.md` for the full synthesis of that run.
 - 2026-09-28T18:09Z — vault HEAD unchanged at `09bec367` for the 17th consecutive fetch after the Tomas 2026 + Vijakumaran 2026 resumption, 0 new vault commits + 1 working-tree modification at `MOCs/MOC-类器官与3D培养.md` (mtime 2026-09-13 11:55:42 +0800, persists uncommitted for 15 calendar days at this fetch), 2 new wiki commits (`53fd10c` daily update 2026-09-28 + `6bafbff` sources-sync 2026-09-28 — the **forty-fifth** consecutive sources-sync), 12-dirty-file baseline (same count as the 2026-09-27T18:19Z fetch — the `53fd10c` daily update cleared `sources/openwiki-version-drift.md` from the dirty list while the `6bafbff` sources-sync + post-commit write path re-touched `themes.md`; net: 0 vs the 12-dirty baseline), carry-forward bump to 47/42/42/35-day. See the "Synthesis-policy — this run (2026-09-28T18:09Z)" section above + the "Latest update — git-repo-1 (2026-09-28T18:09Z)" paragraph on `/quickstart.md` for the full synthesis of that run.
 - 2026-09-25T18:17Z — vault HEAD unchanged at `09bec367` for the 14th consecutive fetch after the Tomas 2026 + Vijakumaran 2026 resumption, 0 new vault commits + 1 working-tree modification at `MOCs/MOC-类器官与3D培养.md` (mtime 2026-09-13 11:55:42 +0800, persists uncommitted for 12 calendar days at this fetch), 2 new wiki commits (`069eef3` daily update 2026-09-25 + `f9bb2e5` sources-sync 2026-09-25 — the **forty-second** consecutive sources-sync), 11-dirty-file baseline (down from 12-dirty at the 2026-09-24T18:07Z fetch — the `069eef3` daily update cleared `sources/git-repo.md` from the dirty list; net: −1 vs the 12-dirty baseline), carry-forward bump to 44/39/39/32-day. See the "Synthesis-policy — this run (2026-09-25T18:17Z)" section above + the "Latest update — git-repo-1 (2026-09-25T18:17Z)" paragraph on `/quickstart.md` for the full synthesis of that run.
 - 2026-09-24T18:07Z — vault HEAD unchanged at `09bec367` for the 13th consecutive fetch after the Tomas 2026 + Vijakumaran 2026 resumption, 0 new vault commits + 1 working-tree modification at `MOCs/MOC-类器官与3D培养.md` (mtime 2026-09-13 11:55:42 +0800, persists uncommitted for 11 calendar days at this fetch), 2 new wiki commits (`dc1a9fb` daily update 2026-09-24 + `17e9faf` sources-sync 2026-09-24 — the **forty-first** consecutive sources-sync), 12-dirty-file baseline (up from 10-dirty at the 2026-09-23T18:10Z fetch — the `17e9faf` sources-sync re-touched the 4 source-sync files; net: +2 vs the 10-dirty baseline), carry-forward bump to 43/38/38/31-day. See the "Synthesis-policy — this run (2026-09-24T18:07Z)" section above + the "Latest update — git-repo-1 (2026-09-24T18:07Z)" paragraph on `/quickstart.md` for the full synthesis of that run.
 - 2026-09-23T18:10Z — vault HEAD unchanged at `09bec367` for the 12th consecutive fetch after the Tomas 2026 + Vijakumaran 2026 resumption, 0 new vault commits + 1 working-tree modification at `MOCs/MOC-类器官与3D培养.md` (mtime 2026-09-13 11:55:42 +0800, persists uncommitted for 10 calendar days at this fetch), 2 new wiki commits (`4c145e2` daily update 2026-09-23 + `6aa1db2` sources-sync 2026-09-23 — the **fortieth** consecutive sources-sync), 10-dirty-file baseline (up from 8-dirty at the 2026-09-22T18:08Z fetch — the `6aa1db2` sources-sync re-touched the 4 source-sync files; net: +2 vs the 8-dirty baseline), carry-forward bump to 42/37/37/30-day. See the "Synthesis-policy — this run (2026-09-23T18:10Z)" section above + the "Latest update — git-repo-1 (2026-09-23T18:10Z)" paragraph on `/quickstart.md` for the full synthesis of that run.
 - 2026-09-22T18:08Z — vault HEAD unchanged at `09bec367` for the 11th consecutive fetch after the Tomas 2026 + Vijakumaran 2026 resumption, 0 new vault commits + 1 working-tree modification at `MOCs/MOC-类器官与3D培养.md` (mtime 2026-09-13 11:55:42 +0800, persists uncommitted for 9 calendar days at this fetch), 2 new wiki commits (`4e257c9` daily update 2026-09-22 + `4ee7fc1` sources-sync 2026-09-22 — the **thirty-ninth** consecutive sources-sync), 8-dirty-file baseline (down from 10-dirty at the 2026-09-21T18:17Z fetch — the `4e257c9` daily update cleared 7 files that the prior daily update had not been able to clean), carry-forward bump to 41/36/36/29-day. See the "Synthesis-policy — this run (2026-09-22T18:08Z)" section above + the "Latest update — git-repo-1 (2026-09-22T18:08Z)" paragraph on `/quickstart.md` for the full synthesis of that run.
 - 2026-09-21T18:17Z — vault HEAD unchanged at `09bec367` for the 10th consecutive fetch after the Tomas 2026 + Vijakumaran 2026 resumption, 0 new vault commits + 1 working-tree modification at `MOCs/MOC-类器官与3D培养.md` (mtime 2026-09-13 11:55:42 +0800, persists uncommitted for 8 calendar days at this fetch), 2 new wiki commits (`5cc20ce` daily update 2026-09-21 + `d5a2b15` sources-sync 2026-09-21 — the **thirty-eighth** consecutive sources-sync), 10-dirty-file baseline (down from 12-dirty at the 2026-09-20T18:07Z fetch), carry-forward bump to 40/35/35/28-day. See the "Synthesis-policy — this run (2026-09-21T18:17Z)" section above + the "Latest update — git-repo-1 (2026-09-21T18:17Z)" paragraph on `/quickstart.md` for the full synthesis of that run.
 - 2026-09-20T18:07Z — vault HEAD unchanged at `09bec367` for the 9th consecutive fetch after the Tomas 2026 + Vijakumaran 2026 resumption, 0 new vault commits + 1 working-tree modification at `MOCs/MOC-类器官与3D培养.md` (mtime 2026-09-13 11:55:42 +0800, persists uncommitted for 7 calendar days at this fetch), 2 new wiki commits (`ea5d9b9` daily update 2026-09-20 + `30c7e85` sources-sync 2026-09-20 — the **thirty-seventh** consecutive sources-sync), 3-dirty-file baseline (down sharply from 5-dirty at the 2026-09-19 fetch — `ea5d9b9` daily update cleared `index.md` + `quickstart.md` + `themes.md` of dirty state), carry-forward bump to 39/34/34/27-day. See the "Synthesis-policy — this run (2026-09-20T18:07Z)" section above + the "Latest update — git-repo-1 (2026-09-20T18:07Z)" paragraph on `/quickstart.md` for the full synthesis of that run.
 - 2026-09-19T18:04Z — vault HEAD unchanged at `09bec367` for the 8th consecutive fetch after the Tomas 2026 + Vijakumaran 2026 resumption, 0 new vault commits + 1 working-tree modification at `MOCs/MOC-类器官与3D培养.md` (mtime 2026-09-13 11:55:42 +0800, persists uncommitted for 6 calendar days at this fetch), 2 new wiki commits (`1ba0fb1` sources-sync 2026-09-19 — the **thirty-sixth** consecutive sources-sync — + `6e2a733` daily update 2026-09-19), 5-dirty-file baseline (down from 11-dirty at the 2026-09-18 fetch), carry-forward bump to 38/33/33/26-day. See the "Synthesis-policy — this run (2026-09-19T18:04Z)" section above + the "Latest update — git-repo-1 (2026-09-19T18:04Z)" paragraph on `/quickstart.md` for the full synthesis of that run.
 - 2026-09-18T18:15Z — vault HEAD unchanged at `09bec367` for the 7th consecutive fetch after the Tomas 2026 + Vijakumaran 2026 resumption, 0 new vault commits + 1 working-tree modification at `MOCs/MOC-类器官与3D培养.md` (mtime 2026-09-13 11:55:42 +0800, persists uncommitted for 5 calendar days at this fetch), 2 new wiki commits (`46a508d` daily update 2026-09-18 + `c6e81a5` sources-sync 2026-09-18 — the **thirty-fifth** consecutive sources-sync), 11-dirty-file baseline (up from 10-dirty at the 2026-09-17 fetch), carry-forward bump to 37/32/32/25-day. See the "Synthesis-policy — this run (2026-09-18T18:15Z)" section above + the "Latest update — git-repo-1 (2026-09-18T18:15Z)" paragraph on `/quickstart.md` for the full synthesis of that run.
 - 2026-09-17T18:22Z — vault HEAD unchanged at `09bec367` for the 6th consecutive fetch after the Tomas 2026 + Vijakumaran 2026 resumption, 0 new vault commits + 1 working-tree modification at `MOCs/MOC-类器官与3D培养.md` (mtime 2026-09-13 11:55:42 +0800, persists uncommitted for 4 calendar days at this fetch), 2 new wiki commits (`3d95e56` daily update 2026-09-17 + `307e038` sources-sync 2026-09-17 — the **thirty-fourth** consecutive sources-sync), 10-dirty-file baseline (down from 11-dirty at the 2026-09-16 fetch), carry-forward bump to 36/31/31/24-day. See the "Synthesis-policy — this run (2026-09-17T18:22Z)" section above + the "Latest update — git-repo-1 (2026-09-17T18:22Z)" paragraph on `/quickstart.md` for the full synthesis of that run.
 - 2026-09-16T18:18Z — vault HEAD unchanged at `09bec367` for the 5th consecutive fetch after the Tomas 2026 + Vijakumaran 2026 resumption, 0 new vault commits + 1 working-tree modification at `MOCs/MOC-类器官与3D培养.md` (mtime 2026-09-13 11:55:42 +0800, persists uncommitted for 3 calendar days at this fetch), 6 new wiki commits (`667730f` daily update 2026-09-14 + `09f47d6` sources-sync 2026-09-14 — the **thirty-first** consecutive sources-sync + `f38cebf` daily update 2026-09-15 + `f5465f9` sources-sync 2026-09-15 — the **thirty-second** consecutive sources-sync + `73dae5e` daily update 2026-09-16 + `ac46732` sources-sync 2026-09-16 — the **thirty-third** consecutive sources-sync), 11-dirty-file baseline (up from 8-dirty at the 2026-09-13 fetch), carry-forward bump to 35/30/30/23-day. See the "Synthesis-policy — this run (2026-09-16T18:18Z)" section above + the "Latest update — git-repo-1 (2026-09-16T18:18Z)" paragraph on `/quickstart.md` for the full synthesis of that run.
 - 2026-09-13T18:08Z — vault HEAD unchanged at `09bec367` for the 2nd consecutive fetch after the Tomas 2026 + Vijakumaran 2026 resumption, 0 new vault commits + 1 working-tree modification at `MOCs/MOC-类器官与3D培养.md` (mtime 2026-09-13 11:55:42 +0800), 4 new wiki commits (`7cfb801` sources-sync 2026-09-12 — the **twenty-ninth** consecutive sources-sync + `999a37d` daily update 2026-09-12 + `0447186` daily update 2026-09-13 + `5f33bd3` sources-sync 2026-09-13 — the **thirtieth** consecutive sources-sync), 8-dirty-file baseline (down from 10-dirty at the 2026-09-11 fetch), carry-forward bump to 32/27/27/20-day. See the "Synthesis-policy — this run (2026-09-13T18:08Z)" section above + the "Latest update — git-repo-1 (2026-09-13T18:08Z)" paragraph on `/quickstart.md` for the full synthesis of that run.
 - 2026-09-11T18:14Z — vault HEAD bumped `391e4713` → `09bec367` (**vault silence streak BROKEN** after 11 calendar days), 2 new vault commits (`1fd63019` Tomas 2026 HGSC + `09bec367` Vijakumaran 2026 brain-organoid ALI oxygen engineering — first v4 Flywheel auto-sink entry), 4 new wiki commits (`299eeab` sources-sync 2026-09-10 twenty-seventh + `1e6a7cb` daily update 2026-09-10 + `2bf104e` daily update 2026-09-11 + `55d930f` sources-sync 2026-09-11 twenty-eighth), 10-dirty-file baseline, 4 carry-forward untracked directories bumped to 30/25/25/18-day, 1 new untracked `NO` file. See the "Synthesis-policy — this run (2026-09-11T18:14Z)" section above + the "Latest update — git-repo-1 (2026-09-11T18:14Z)" paragraph on `/quickstart.md` for the full synthesis of that run.
 - 2026-09-09T18:11Z — vault HEAD unchanged at `391e4713`, 2 new wiki commits (`f7450e9` + `7e2072c` — the **twenty-sixth** consecutive sources-sync), 10-dirty-file baseline, the 4 carry-forward untracked directories bumped to 29/24/24/17-day carry-forward. See [`/themes/05-robin-research.md`](/themes/05-robin-research.md) + `/quickstart.md` for the full synthesis of that run.
 - 2026-09-10T18:19Z — manifest written by a prior ingestion cycle but no corresponding wiki update (the wiki HEAD was still `299eeab` at the 2026-09-10T18:19Z manifest timestamp, between the `7e2072c` 2026-09-09 sources-sync and the `1e6a7cb` 2026-09-10 daily update). The 2026-09-10T18:19Z manifest observed the same vault HEAD `391e4713` (vault still silent at that timestamp).
 Z — manifest written by a prior ingestion cycle but no corresponding wiki update (the wiki HEAD was still `299eeab` at the 2026-09-10T18:19Z manifest timestamp, between the `7e2072c` 2026-09-09 sources-sync and the `1e6a7cb` 2026-09-10 daily update). The 2026-09-10T18:19Z manifest observed the same vault HEAD `391e4713` (vault still silent at that timestamp).
@@ -1,30 +1,25 @@
 # Files
- [4-27 SOP 实战 vs 实现差异 (2026-07-27 Tasevska 2025 重做教训)](2026-07-27-4-27-sop-vs-implementation.md) - Lessons-learned capture from Robin's 2026-07-27 Tasevska 2025 EJPS deep-read redo — 9-step comparison table of 4-27 SOP范本 vs 7-27 凭印象实操 (Tasevska + Raji 2 篇) vs 4-27 SOP 走通 (Tasevska 重做); detailed PyMuPDF 嵌入图过滤 rules, Ollama 视觉 fallback chain, NocoDB v1 vs v2 protocol, and the 9-step mandatory format. Applies to every literature-deep-read invocation. Companion to `/sources/ldr-report-template.md`.
+- [4-27 SOP 实战 vs 实现差异 (2026-07-27 Tasevska 2025 重做教训)](2026-07-27-4-27-sop-vs-implementation.md)
- [Agents 代理商档案索引 — 跨 agent CRM 同步](agents.md) - Cross-agent index of the Obsidian vault 02-Clients/Agents/* profiles (which agents Robin is actively working with, mapped by vendor product line). Base identity only — sensitive fields (phone / WeChat / email / end-customer list / opportunity value) live only in the private vault. Updated 2026-08-07 with _known_associations.md product-line → agent → end-customer mapping.
+- [Agents 代理商档案索引 — 跨 agent CRM 同步](agents.md)
- [全国经销商地图 (2026-08-07 时点)](distributors-china-2026.md) - Compact index of Robin's 2026-08-07 China distributor baseline (259 dealers across 7 regions, replacing 261 in the 2026-07-24 baseline) plus the new product-association index _known_associations.md. Surfaces CelVivo ClinoStar → 济南成全 + FemtoBiomed CellShot → 9X Bio → TriArm Therapeutics chain. Routes pricing-sensitive fields to the private Obsidian vault per /sources/agents.md privacy rule.
+- [全国经销商地图 · 2026-07-24 时点](distributors-china-2026.md)
- [飞书邮箱 (Robin customer mailbox)](feishu-mail.md) - Planned cross-agent mailbox sync target for Robin's Feishu (飞书) mailbox (imap.feishu.cn:993 / imap.larksuite.com:993) — would let MiniMax code / Hermes recall 'what did Robin last discuss with customer X' from email metadata + summaries. Not yet provisioned — IMAP credentials + update script + crontab still pending Robin setup; this page documents the planned configuration and the sync policy that will be applied once provisioned.
+- [飞书邮箱 (Robin customer mailbox)](feishu-mail.md)
- [Git repo — evidence index (Obsidian vault + OpenWiki wiki, Robin)](git-repo.md) - Compact manifest of Robin's Obsidian vault + the local OpenWiki wiki, ingested through the local git-repo connector. **Latest fetch (2026-09-30T18:24Z — 46th git-repo-1 fetch since 2026-08-07): vault HEAD unchanged at `09bec367` for the 19th consecutive fetch after the Tomas 2026 + Vijakumaran 2026 resumption; wiki HEAD bumped `2fccbf0` → `1d3c470` via 2 new automated wiki commits (`5c788cc` daily update 2026-09-30 + `1d3c470` sources-sync 2026-09-30 — the **forty-seventh** consecutive sources-sync); 1 working-tree modification at `MOCs/MOC-类器官与3D培养.md` (mtime 2026-09-13 11:55:42 +0800 — persists uncommitted for 17 calendar days at this fetch); 11-dirty-file baseline (vs the 13-dirty baseline at the 2026-09-29T18:14Z fetch — the `5c788cc` daily update cycle cleared `sources/git-repo.md` + `sources/README.md` + `sources/literature.md` + `D tmp/check_themes.py` (deletion) from the dirty list; the `1d3c470` sources-sync re-touched the 4 source-sync files (`sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md`); the post-sources-sync synthesis-side write path re-touched `index.md` + `quickstart.md` + `sources/hackernews.md` + `sources/index.md` + `sources/web-search.md` + `themes.md`; net: −2 vs the 13-dirty baseline); carry-forward bump 48/43/43/36 → **49/44/44/37-day** (highest carry-forward durations of the 2026-08-07 streak).** Two configured repos: obsidian-vault at /home/ldw/workspace (main branch, HEAD `09bec367`, 2026-09-11, vault HEAD unchanged at `09bec367` for the 19th consecutive fetch after the Tomas 2026 + Vijakumaran 2026 resumption; the MOC working-tree modification persists uncommitted for 17 calendar days at this fetch); and openwiki-wiki at /home/ldw/.openwiki/wiki (main branch, HEAD `1d3c470`, 2026-09-30, bumped from `2fccbf0` via 2 automated commits in the 24-hour window — `5c788cc` daily update + `1d3c470` sources-sync forty-seventh). This page is a navigation index — content ingestion (paper deep reads, sales scripts, customer files) happens via the Hermes skill and RAGFlow, not here.
+- [Git repo — evidence index (Obsidian vault, Robin)](git-repo.md)
-
+- [Hacker News — evidence index](hackernews.md)
- [Hacker News — evidence index](hackernews.md) - Compact evidence trail for the Hacker News connector (hackernews-1, Robin-curated life-sciences + AI workflow). Synthesis lives on /themes.md, /commitments.md, etc.; this page only records ingestion coverage and notable items. 50th pull (2026-09-30) anchors on **`49901736` Livenerf: Has Opus 5.5 been nerfed yet?** (828 pts top+best + 346 cmts, github.com/ninjahawk/livenerf — **HIGHEST ENGAGEMENT ITEM OF THE 2026-09-30 PULL**) + **`49906637` You Said No MCP** (476 pts top+best + 276 cmts, earendil.com — 2nd-highest) + **`49910553` The AI Race Just Got Awkward** (341 pts best + 333 cmts, insufferable.dev — would-be 42nd AI-vendor-business-stack cluster entry candidate) + **`49902382` Show HN: Ledge.sh — Runnable Markdown Notes** (30 pts top + 20 cmts, ledge.sh — named-stack-adjacent markdown-substrate cross-walk) + **`49911995` Launch HN: Magnitude (YC S25) — Self-optimizing inference engine for agents** (19 pts top + 6 cmts, github.com/magnitudedev/magnitude — would-be 30th open-weight-LLM cluster entry candidate + 15th self-hosted-agentic-substrate cluster entry candidate); 49th pull (2026-09-29) anchors on the **3-Jev-entry same-day triple** spanning 558 + 185 + 42 = 785 pts in a single pull: **`49883844` "Jeff — Jev-compatible 0.8B decision models, trained at home, ~30 ms"`** (558 pts best + 215 cmts — by `firelex`, https://github.com/firelex/jeff — **HIGHEST-ENGAGEMENT Jev-family ITEM SINCE the 2026-09-16 `49717558` System One Models + Jev 1728 pts original launch**; **would-be 9th Jev-family adjacent-not-promoted entry candidate** + **28th open-weight-LLM cluster entry candidate**, adjacent-not-promoted per scope because the entry is a personal-GitHub project rather than a vendor canonical release + the cluster's promotion discipline has been "vendor canonical release + strong engagement" + firelex Jeff is not on Robin's named daily-driver stack — Hermes / MiniMax-M3+H3 / OpenWiki / RAGFlow / NocoDB / SeaFile / Codex CLI are the named agents) + **`49891290` "Jeeves. Reasoning improves Jev-like decision models"`** (185 pts top + 77 cmts — by `nicowaltz`, https://github.com/PostHog/jeeves — **github.com/PostHog/jeeves PostHog-maintained Jeeves library**; the **0.42 cmts-to-upvote ratio**; the **PostHog-maintained GitHub library framing** with "reasoning improves Jev-like decision models"; would-be 10th Jev-family entry candidate, **adjacent-not-promoted per scope** because the entry is a PostHog-maintained GitHub library rather than a vendor canonical release + PostHog is not on Robin's named daily-driver stack) + **`49891769` "Show HN: Jevstiller — Distill Jev into a local model, with a disagreement bound"`** (42 pts top + 6 cmts — by `tgluck`, https://jevstiller.pages.dev/posts/the-guarantee/ — Show HN distillation tool with disagreement bound from a 0.8B Jev-family local model; would-be 11th Jev-family entry candidate, adjacent-not-promoted per scope because 42-pt engagement is well below the 100-pt cluster entry bar + the entry is a Show HN launch rather than a vendor canonical release) — all three adjacent-not-promoted per scope because personal-GitHub / PostHog-GitHub / Show-HN framings rather than vendor canonical releases; cross-walks to the 2026-09-16 `49717558` System One Models + Jev 1728 pts + 2026-09-18 `49752041` OpenJev 405 pts + 2026-09-21 `49807815` Kev Jev-like 317 pts + 2026-09-26 `49848269` Ollaya 553 pts + 2026-09-26 `49853175` Jev-wrapper 120 pts + 2026-09-28 `49846632` Decide-Jev-decisions-by-vsekhar 0 cmts Algolia substring-noise entries) + **OpenAI vendor canonical release** **`49896586` "GPT 6.1 Sol"`** (289 pts top+best + 206 cmts — by `crorella`, https://openai.com/index/introducing-gpt-6-1-sol/ — **OpenAI's GPT 6.1 Sol canonical release on openai.com**; the **0.71 cmts-to-upvote ratio**; the **289-pt engagement is the 10th-highest single-item of the 2026-09-29 pull**; the **GPT 6.1 Sol release continues the 2026-09-04 GPT-6 Astra + 2026-09-23 GPT-6 Sol-and-Luna family**; **would-be 11th closed-weight-M3-comparison-anchor cluster entry candidate** + **35th AI-vendor-business-stack cluster entry candidate**, adjacent-not-promoted per scope because (a) OpenAI is closed-weight and not on Robin's named daily-driver stack — Hermes / MiniMax-M3+H3 / OpenWiki / RAGFlow / NocoDB / SeaFile / Codex CLI are the named agents, (b) the cluster's promotion discipline has been "vendor canonical release + strong engagement" and the 2026-09-29 entry sits at the lower-engagement tail of the cluster pattern, (c) the existing closed-weight-M3 cluster already covers the GPT-6 family via the 2026-09-04 GPT-6 Astra 2080 pts + 2026-09-23 GPT-6 Sol and Luna 1683 pts + 2026-09-05 GPT-6 Astra on OpenRouter 279 pts entries) + **OpenAI companion product launches** — **`49896604` "Dots"`** (192 pts top + 102 cmts, https://openai.com/index/introducing-dots/ — would-be 12th closed-weight-M3 cluster entry candidate Line truncated
+- [文献精读 Master Template (Robin 7-27 实战版, "真适合浏览" 1 文件)](ldr-report-template.md)
- [文献精读 Master Template (Robin 7-27 实战版, "真适合浏览" 1 文件)](ldr-report-template.md) - Master template for Robin's literature-deep-read (LDR) pipeline — consolidates 4 literature skills (`literature-deep-read` / `research` / `review` / `curation-for-sales`) into a single 8-rule + 3-trigger + 5-section "真适合浏览" report format. Synthesized from 4-27 SOP范本 + 7-27 实战 lessons (Tasevska / Raji / Bosnjakovic). Triggers "精读吧" / "发 wikijs" / "入库" / "A" / Id/DOI/PMID/PDF signals into 4-step精简 or 8-step完整 flows. PDF全文必传 + PyMuPDF xref去重 + 9项强制 + SeaFile hostname `fb.biokingdom.top` + NocoDB v1 JSON + 3张真图 + `journal-year-topic` 报告路径.
+- [Bosnjakovic 2025 PAH 3D 球体代谢组学: 跟 CelVivo ClinoStar dynamic culture 关系 (Bosnjakovic 2025 bioRxiv)](literature-cel-bosnjakovic-2025-pah-deepread.md)
- [Bosnjakovic 2025 PAH 3D 球体代谢组学: 跟 CelVivo ClinoStar dynamic culture 关系 (Bosnjakovic 2025 bioRxiv)](literature-cel-bosnjakovic-2025-pah-deepread.md) - Deep-read synthesis of Bosnjakovic A et al. 2025 bioRxiv preprint (DOI 10.1101/2025.07.10.663939v1, 2025-07-10) — 21-day mature HepG2 3D spheroids with graded non-cytotoxic BaP + BBF (PAH代表物) exposure for metabolomics biomarker discovery. Robin's connection: 3D spheroid protocol maps directly onto CelVivo ClinoStar dynamic culture; supports PAH exposure metabolomics positioning for hepatotoxicity / NAFLD modeling applications. 精读 2026-07-27.
+- [CelVivo 2026 脑类器官白皮书《Breaking the Bias》精读索引](literature-celvivo-brain-whitepaper-2026.md)
- [CelVivo 2026 脑类器官白皮书《Breaking the Bias》精读索引](literature-celvivo-brain-whitepaper-2026.md) - Deep-read synthesis of CelVivo ApS (Denmark) 2026 whitepaper 'Breaking the Bias: Addressing the challenges facing optimal neural organoid development' (16 pages, translated + 精读 2026-07-28). Synthesizes CelVivo's positioning on neural organoid long-term culture and the clinical-translation path. Direct vendor-channel evidence for the CelVivo ClinoStar / ClinoReactor portfolio on brain organoid applications — companion to academic literature flywheel-sync.
+- [Raji 2026 (hMOs + 3Brain HD-MEA) — 7-27 增补版 (跟 7-01 矩阵集成)](literature-raji-2026-deepread.md)
- [Liu 2026 — shape-conformal porous frameworks for full coverage of neural organoid electrophysiology (Nat Biomed Eng, Rogers Lab)](literature-liu-2026-nbme-shape-conformal-organoid-deepread.md) - Deep-read synthesis of Liu N et al. (2026) Nature Biomedical Engineering — shape-conformal porous framework + adaptive genetic algorithm + flexible-electronics microlattice for full-surface (>90%) neural organoid electrophysiology at 3000-8000 channels per organoid (vs 200-1000 traditional MEA); weeks-long stable recording; epilepsy/AD disease modeling.
+- [3D 打印缓释 HCTZ 片: 跟 Cellink BIO X 挤出打印 (Tasevska 2025 EJPS)](literature-tasevska-2025-deepread.md)
- [Miao 2025 — co-development of mesoderm and endoderm enables organotypic vascularization in lung and gut organoids (Cell v2)](literature-miao-2025-cell-vascularization-v2-deepread.md) - Deep-read synthesis of Miao Y et al. (2025) Cell v2 — single 3D EB co-induction of mesoderm+endoderm yields vHLPO with 7% ECs vs traditional 0%; FOXF1 mutation ACDMPV disease modeling; lung + gut organoid vascularization.
+- [Literature Deep-Reads — 跨 agent 精读索引](literature.md)
 - [Raji 2026 (hMOs + 3Brain HD-MEA) — 7-27 增补版 (跟 7-01 矩阵集成)](literature-raji-2026-deepread.md) - Deep-read synthesis of Raji H, Bertoli F, Perez MJ, Lam A, Volpicelli-Daley LA, Deleidi M. 2026 Molecular Psychiatry (Nature 子刊, s41380-026-03667-4, DOI 10.1038/s41380-026-03667-4, IF 11) — human midbrain organoids (hMOs) with WNT modulation, dopaminergic neuron differentiation, bioreactor culture, and 3Brain HD-MEA electrophysiology for Parkinson's disease modeling. 7-01 实战范本 (page 1622) + 7-27 增补版 integrated with 3-paper 3Brain MEA matrix (Raji / Pali / Wei) and 4 product-line complementarity chain (CelVivo ClinoStar + Cellink BIO X + 3Brain HD-MEA + FemtoBiomed CellShot).
 - [Sharma 2026 — vascularized retinal organoid RGC survival and maturation (Cell Stem Cell)](literature-sharma-2026-cell-stem-cell-vascularized-retinal-organoid-rgc-deepread.md) - Deep-read synthesis of Sharma K et al. (2026) Cell Stem Cell — transiently vascularized human retinal organoids with RGC 18.2% vs ctrl-RO 1.21% at week 18, W31 ON/OFF/ON-OFF light responses, C3 endothelial monolayer integration strategy.
 - [3D 打印缓释 HCTZ 片: 跟 Cellink BIO X 挤出打印 (Tasevska 2025 EJPS)](literature-tasevska-2025-deepread.md) - Deep-read synthesis of Tasevska T et al. 2025 European Journal of Pharmaceutical Sciences 206:106998 (DOI 10.1016/j.ejps.2024.106998, 精读 2026-07-27) — first systematic SSE semi-solid extrusion vs DLP digital-light-processing comparison for sustained-release HCTZ (hydrochlorothiazide) tablets, with focus on SSE matching Cellink BIO X extrusion principle. Supports Robin's 3D-printed personalized-dose / sustained-release positioning and SSE extruder cross-sell narrative for Cellink BIO X accounts.
 - [Literature Deep-Reads — cross-agent deep-read index](literature.md)
 - [NocoDB 文献库索引 — 跨 agent 数据层](nocodb.md)
- [OpenWiki Upgrade Drift (auto-generated)](openwiki-version-drift.md)
+- [OpenWiki 速查手册 (Robin 一次聊清, 直接拿来用)](OpenWiki%E9%80%9F%E6%9F%A5%E6%89%8B%E5%86%8C.md)
- [OpenWiki 速查手册 (Robin 一次聊清, 直接拿来用)](OpenWiki%E9%80%9F%E6%9F%A5%E6%89%8B%E5%86%8C.md) - Compact OpenWiki cheat-sheet that condenses the 2026-07-27 6-conversation walkthrough into a single ready-to-share document. Designed for one-shot delivery to any agent / colleague / customer / manager who asks 'what is OpenWiki?' — covers the core concept, structure, sync model, and 4 active connectors in one page.
+- [RAGFlow 文档采样索引](ragflow-documents.md)
- [RAGFlow 文档采样索引](ragflow-documents.md) - Document-level sample index of Robin's RAGFlow instance (http://10.10.10.254:9980) — 18 KBs / 32709 total docs / 401 sample entries (last sync 2026-08-03). Captures the 30-doc-per-request server-side limit + offset bug that forces 12 large KBs to single-page samples. Lets MiniMax code / Hermes see 'what's in each KB' without SQL queries; complements `/sources/ragflow.md` (KB-level health + counts).
+- [Ragflow](ragflow.md)
- [RAGFlow 全文检索索引 (Robin KB system)](ragflow.md)
+- [Sources](README.md)
- [Sources](README.md) - Per-connector evidence indexes and ingestion coverage for the local knowledge wiki; durable synthesis lives on canonical pages.
+- [RustDesk 自建 hbbs 完整配置笔记 (2026-08-05)](rustdesk-sop.md)
- [RustDesk 自建 hbbs 完整配置笔记 (2026-08-05)](rustdesk-sop.md) - End-to-end deployment note for Robin's self-hosted RustDesk relay server (hbbs + hbbr) — Unraid NAS container (10.10.10.254) + OpenWrt reverse-proxy (10.10.10.252) + Tencent Light Cloud (43.160.207.177) + ITX client (192.168.31.14), with permanent password + key config. Supports remote control of the ITX 24h host (per `/commitments.md` `itx-24h-host-build-2026-q3`) and Robin's travel-laptop remote-access workflow.
+- [CelVivo 销售弹药清单 (2026-07-16 实战索引)](sales-ammunition.md)
 - [CelVivo 销售弹药清单 (2026-07-16 实战索引)](sales-ammunition.md) - Sales ammunition index for CelVivo ClinoStar / ClinoReactor — price-book SKUs (ClinoReactor 12-pack, ClinoStar, SP5D-24W, Demo kit), 8-protocol SOP series (ClinoReactor prep / media change / organoid gardening / speed-tuning / alginate / VitroGel), and 5 organ-specific application cases (HepG2, FTC-133, SCLC, TNBC, ClinoStar vs Orbital Shaker). Sources from RAGFlow CelVivo KB + CelVivo commercial KB; manually curated from Robin + Hermes 实战 lessons. Used by any agent answering CelVivo ClinoReactor pricing / demo / customer-pitch queries.
 - [SeaFile 大文件存储索引](seafile.md)
- [CelVivo + Vault 实时 mtime 快照 (2026-07-16 快照)](vault-mtime-snapshot-2026-07-16.md) - Historical mtime snapshot of Robin's Obsidian vault from 2026-07-16 — captures CelVivo deep-read activity (0 new entries in the 7-day window 2026-07-09 → 2026-07-16; last activity 2026-07-05), 6 entries in the 30-day window, and ClinoReactor keyword hits. Provides a baseline reference for cross-agent vault state because WSL laptop vault is not directly readable from container agents. Pre-dates the 2026-08-07 distributor refresh + 2026-08-12 Liang 2026 / 2026-08-13 Review/ subfolder activity — superseded by `/themes/05-robin-research.md` for current vault state.
+- [CelVivo + Vault 实时 mtime 快照 (2026-07-16 快照)](vault-mtime-snapshot-2026-07-16.md)
- [Web Search Evidence](web-search.md) - Compact ingestion coverage for the web-search-1 Tavily lane tracking CelVivo, 3Brain, Cellink, and related organoid news.
+- [Web Search Evidence](web-search.md)
 - [Wiki.js 索引 — 跨 agent 文档发布层](wikijs.md)
@@ -1,8 +1,7 @@
 ---
 type: "Reference"
 title: "文献精读 Master Template (Robin 7-27 实战版, \"真适合浏览\" 1 文件)"
-description: "Master template for Robin's literature-deep-read (LDR) pipeline — consolidates 4 literature skills (`literature-deep-read` / `research` / `review` / `curation-for-sales`) into a single 8-rule + 3-trigger + 5-section \"真适合浏览\" report format. Synthesized from 4-27 SOP范本 + 7-27 实战 lessons (Tasevska / Raji / Bosnjakovic). Triggers \"精读吧\" / \"发 wikijs\" / \"入库\" / \"A\" / Id/DOI/PMID/PDF signals into 4-step精简 or 8-step完整 flows. PDF全文必传 + PyMuPDF xref去重 + 9项强制 + SeaFile hostname `fb.biokingdom.top` + NocoDB v1 JSON + 3张真图 + `journal-year-topic` 报告路径."
+openwiki_generated: true
 tags: [ldr-template, literature-deep-read, sop, reference, 2026-08-13]
 ---
 # 文献精读 Master Template (Robin 7-27 实战版, "真适合浏览" 1 文件)
@@ -29,7 +28,8 @@ tags: [ldr-template, literature-deep-read, sop, reference, 2026-08-13]
 | 3. **9 项强制 + 创新点/局限性/学术启示 3 段** (4-27 SOP page 946 标杆) | 7-27 教训 (7-17 2 篇缺 3 段) | 模板下面 §3 |
 | 4. **SeaFile URL hostname `fb.biokingdom.top`** (不是少 o) | 7-27 教训 (Tasevska 5 URL 错) | 验证 share-link 真能开 |
 | 5. **NocoDB v1 + JSON body** (4-27 SOP 实战新发现, 范本 v2 失败 3 次) | 7-27 Tasevska 入库 | `POST /api/v1/db/data/wzg1wtad/p2z4g0s687axyvu/{table_id}` |
-| 6. **3 张真图 `![]()`** (SeaFile URL), 不**只**文字图说啥 | 7-27 教训 (Tasevska 重做/Raji 增补版漏图) | markdown image syntax (`alt text` + parenthesized URL), 3 段三段式图注 |
+<!-- openwiki: broken internal link [url] file "url" does not exist. Fix the href or restore the target, then delete this comment. -->
 | 6. **3 张真图 `![]()`** (SeaFile URL), 不**只**文字图说啥 | 7-27 教训 (Tasevska 重做/Raji 增补版漏图) | `!\[alt\](url)` markdown, 3 段三段式图注 |
 | 7. **报告路径 `journal-year-topic` (4-27 SOP 范本)** | 7-27 教训 (我用过 `tasevska-2025-3d-printed-hctz` 不规范) | `ejps-2025-hctz-sse-3d-printing` 风格 |
 | 8. **精简 4 步 vs 完整 8 步按 Robin 信号自动判断** | 7-27 实战 (Tasevska 简化 App Note 类) | 模板下面 §2 |
@@ -1,8 +1,7 @@
 ---
 type: "Reference"
 title: "Bosnjakovic 2025 PAH 3D 球体代谢组学: 跟 CelVivo ClinoStar dynamic culture 关系 (Bosnjakovic 2025 bioRxiv)"
-description: "Deep-read synthesis of Bosnjakovic A et al. 2025 bioRxiv preprint (DOI 10.1101/2025.07.10.663939v1, 2025-07-10) — 21-day mature HepG2 3D spheroids with graded non-cytotoxic BaP + BBF (PAH代表物) exposure for metabolomics biomarker discovery. Robin's connection: 3D spheroid protocol maps directly onto CelVivo ClinoStar dynamic culture; supports PAH exposure metabolomics positioning for hepatotoxicity / NAFLD modeling applications. 精读 2026-07-27."
+openwiki_generated: true
 tags: [literature-deep-read, celvivo-clinostar, hepG2, PAH, metabolomics, 3d-spheroid, 2026-08-13]
 ---
 # Bosnjakovic 2025 PAH 3D 球体代谢组学: 跟 CelVivo ClinoStar dynamic culture 关系 (Bosnjakovic 2025 bioRxiv)
@@ -1,8 +1,7 @@
 ---
 type: "Reference"
 title: "CelVivo 2026 脑类器官白皮书《Breaking the Bias》精读索引"
-description: "Deep-read synthesis of CelVivo ApS (Denmark) 2026 whitepaper 'Breaking the Bias: Addressing the challenges facing optimal neural organoid development' (16 pages, translated + 精读 2026-07-28). Synthesizes CelVivo's positioning on neural organoid long-term culture and the clinical-translation path. Direct vendor-channel evidence for the CelVivo ClinoStar / ClinoReactor portfolio on brain organoid applications — companion to academic literature flywheel-sync."
+openwiki_generated: true
 tags: [literature-deep-read, celvivo, brain-organoid, clinostat, long-term-culture, whitepaper, vendor-channel, 2026-08-13]
 ---
 # CelVivo 2026 脑类器官白皮书《Breaking the Bias》精读索引
@@ -1,110 +0,0 @@
 ---
 type: "Reference"
 title: "Liu 2026 — shape-conformal porous frameworks for full coverage of neural organoid electrophysiology (Nat Biomed Eng, Rogers Lab)"
 description: "Deep-read synthesis of Liu N et al. (2026) Nature Biomedical Engineering — shape-conformal porous framework + adaptive genetic algorithm + flexible-electronics microlattice for full-surface (>90%) neural organoid electrophysiology at 3000-8000 channels per organoid (vs 200-1000 traditional MEA); weeks-long stable recording; epilepsy/AD disease modeling."
 tags: [literature, deep-read, neural-organoid, hd-mea, flexible-electronics, microlattice, 3d-bioprinting-adjacent, celvivo-clinostar-adjacent, 3brain-hd-mea, robin-picked-papers]
 ---
 # Liu 2026 — shape-conformal porous frameworks for full coverage of neural organoid electrophysiology (Nat Biomed Eng, Rogers Lab)
 > Liu N, Shiravi S, Jin T, Liu J, Zhu Z, Li J, Cheung I, Zhang H, Wang Y, Li Q, Xu Z, Zeng L, ... Rogers JA. | **Nature Biomedical Engineering** | 2026 | DOI: 10.1038/s41551-026-01620-y
 > Wiki.js Id 1692 — https://wiki.biokingdom.top/zh/literature/liu-2026-nbme-shape-conformal-organoid
 > NocoDB row 1 in **new table `Robin_Picked_Papers`** (created 2026-08-08, table_id `mbjo0wb56qv1qly`)
 > SeaFile PDF: https://fb.biokingdom.top/f/6da50240729e41bdb369/?dl=1 (5 figures)
 > Deep-read date: 2026-08-08; flywheel-sync `flywheel_index` completed 2026-08-08T09:59:40Z
 > Vendor deep-read report: `/home/ldw/workspace/Liu2026_NBME_shape_conformal_organoid.md`
 **Tags:** neural organoid | shape-conformal framework | flexible electronics | adaptive genetic algorithm | microlattice | 3D bioprinting adjacent | HD-MEA next-gen | electrophysiology | epilepsy disease modeling | Alzheimer disease modeling | Rogers Lab (Northwestern)
 **Special note:** This is the **first entry** in the new NocoDB table `Robin_Picked_Papers`, created 2026-08-08 per Robin's instruction to capture papers Robin hand-picks / provides outside the regular PubMed triage. The table is separate from the existing `Organoid_Literature` table.
 ---
 ## 0. Research background and core question
 **Background:** Traditional multi-electrode arrays (MEAs) record neural organoid electrophysiology from a flat 2D electrode grid sitting at the bottom of the organoid — capturing only the bottom-surface electrical activity (5-15% of the organoid surface). This is fundamentally limiting for understanding 3D neural network dynamics. **This study** (Rogers Lab, Northwestern) introduces a **shape-conformal porous framework** that wraps the entire organoid surface (2D → 3D buckling transition) and provides >90% surface coverage at 3000-8000 channels per organoid.
 **Core questions:**
 - Can a flexible-electronics framework be designed to conformally wrap a 3D organoid?
 - What channel density and surface coverage does the framework achieve vs traditional MEA?
 - Can the framework record weeks-long stable signals without mechanical or electrical failure?
 - Can bi-directional electrical stimulation + optogenetic stimulation be integrated?
 - Can the framework detect disease-network signatures (epilepsy, AD) in patient-derived organoids?
 ## 1. Key findings (4-paragraph three-segment format — 4-27 SOP standard)
 ### Key finding 1: Shape-conformal porous framework gives >90% surface coverage (vs 5-15% traditional MEA)
 | What was done | What was found | What it means |
 | --- | --- | --- |
 | Inverse design + Euler-Bernoulli beam theory + adaptive genetic algorithm (AGA); 2D flexible-electronics film → 3D framework via automatic buckling | >90% full surface coverage vs 5-15% traditional MEA; 3000-8000 channels per organoid (vs 200-1000); framework conforms to organoid shape without compression | First 3D electrophysiology platform that captures the **whole-organoid** electrical activity — enables true 3D neural network dynamics analysis rather than bottom-surface-only |
 ### Key finding 2: Weeks-long stable recording
 | What was done | What was found | What it means |
 | --- | --- | --- |
 | Continuous recording over 4+ weeks in vitro; bi-directional electrical stimulation (evoked responses); optogenetic stimulation compatibility | Recording stable through weeks (no mechanical failure, no signal drift); bi-directional electrical stimulation produces expected evoked responses; optogenetic stimulation + recording compatibility | First platform that supports **long-term drug screening** — 4-week drug exposure with continuous electrophysiology readout was previously impossible |
 ### Key finding 3: Epilepsy + Alzheimer's disease modeling
 | What was done | What was found | What it means |
 | --- | --- | --- |
 | Patient-derived iPSC cortical organoids from epilepsy + Alzheimer's donors vs healthy controls | Disease-network signatures detected (epileptiform bursts, AD-specific oscillation patterns); drug screening proof-of-concept | Patient-derived organoid drug screening becomes a **first-tier preclinical model** for neurological disease — supports personalized medicine workflows |
 ### Key finding 4: 3D microlattice fabrication with PI/Parylene substrate
 | What was done | What was found | What it means |
 | --- | --- | --- |
 | Flexible-electronics thin film + microlattice patterning on PI/Parylene substrate; 2D-to-3D buckling transition | High-resolution microlattice with controlled porosity; mechanical compliance matched to neural tissue; optical transparency for optogenetics | The microlattice fabrication technique is a **3D bioprinting-adjacent** technology — bridges flexible-electronics manufacturing and tissue-engineering scaffold fabrication |
 ## 2. Methodology
 | Step | Content | Key parameters |
 | --- | --- | --- |
 | 1. Framework design | Inverse design + Euler-Bernoulli beam theory + adaptive genetic algorithm (AGA) | — |
 | 2. Fabrication | Flexible-electronics thin film + microlattice patterning | PI/Parylene substrate |
 | 3. Interface | 2D-to-3D automatic buckling transition (wraps organoid surface) | — |
 | 4. Recording | >90% surface coverage, 3000-8000 channels per organoid, 32 kHz sampling | Weeks-long stable |
 | 5. Stimulation | Bi-directional electrical + optogenetic | — |
 | 6. Validation | Human iPSC cortical organoids + long-term electrophysiology | 4+ weeks |
 | 7. Disease modeling | Epilepsy + AD patient-derived organoids | — |
 ## 3. Boundaries / Limitations
 - **Currently validated mainly in cortical organoids** — generalization to other organoid types (midbrain, spinal, retinal) not yet demonstrated.
 - **Framework fabrication is complex** — requires Rogers Lab's specialized flexible-electronics fabrication pipeline; not yet a turnkey product.
 - **Higher channel count → bigger data processing burden** — 3000-8000 channels at 32 kHz produces terabytes per week; new analysis pipelines required.
 - **Disease modeling validated only in epilepsy + AD** — extension to other neurological diseases (PD, HD, ALS) not yet published.
 ## 4. Product relevance (vendor cross-mapping)
 | Vendor / product | Rating | Evidence |
 | --- | ---: | --- |
 | **HD-MEA (3Brain or next-gen)** | **5** | 10-50× existing channels — Liu 2026's framework is the **direct next-generation design reference** for HD-MEA platforms. Robin should sell 3Brain's current 4096-electrode Accura-3D as the existing best-in-class and Liu 2026 as the forward-looking 3D-coverage direction |
 | **3D bioprinting (microlattice)** | **5** | The microlattice fabrication technique depends on 3D printing-class resolution. Cellink BIO X / Lumen X cannot directly print at this resolution today, but the field direction is clear: future bioprinters will integrate flexible-electronics fabrication |
 | **CelVivo ClinoStar** | 4 | Organoid culture downstream — Liu 2026's framework is a readout tool; ClinoStar is the culture partner. Long-term maturation + functional readout is the canonical ClinoStar → HD-MEA workflow |
 | **Flexible electronics** | 4 | PI/Parylene substrate stack is standard flexible-electronics material science — not Robin's vendor line directly but the methodology is in scope for the broader Cellink / BIONOVA product family |
 | **Patient-derived organoid drug screening** | **5** | First long-term high-throughput electrophysiology drug screening platform. Patient-derived organoid drug screening becomes feasible for neurological disease at scale |
 ## 5. Why this matters for Robin's portfolio
 - **Highest product-relevance cluster of all 3 flywheel-sync papers.** Two rating-5 products (HD-MEA + 3D bioprinting) and three rating-4 products (CelVivo ClinoStar, flexible electronics, patient-derived drug screening) all converge on Liu 2026's framework.
 - **3Brain HD-MEA roadmap signal:** Liu 2026 establishes a **next-gen 3D-coverage HD-MEA design** that 3Brain will need to respond to. Robin should track whether 3Brain has a flexible-electronics / shape-conformal framework on their roadmap.
 - **3D bioprinting cross-sell:** the microlattice fabrication technique is a 3D bioprinting-adjacent technology — Robin should pitch Liu 2026 to Cellink to understand whether BIONOVA X or Lumen X can fabricate flexible-electronics-compatible microlattices.
 - **Patient-derived organoid drug screening pipeline:** Liu 2026 + Miao 2025 together establish a complete pipeline — CelVivo ClinoStar culture → HD-MEA / shape-conformal framework readout → patient-derived drug screening. Robin's 4-vendor portfolio (CelVivo / 3Brain / Cellink / Femtobiomed) covers every link.
 - **First entry in `Robin_Picked_Papers` table:** new NocoDB table created 2026-08-08 per Robin instruction to capture papers Robin hand-picks / provides outside the regular PubMed triage. This is a structural change in the literature pipeline.
 ## 6. Forward / 转发语 + 落款
 > Liu 2026 是 neural organoid 全表面电生理首篇 — **形状共形多孔框架 + 3000-8000 通道 / 类器官 (>90% 全表面覆盖) vs 传统 MEA 5-15% (200-1000 通道)**, 数周稳定记录 + 双向电刺激 + 光遗传 + 癫痫/AD 疾病建模。3Brain HD-MEA 下一代设计直接参考 (rating 5), Cellink 3D 打印 microlattice rating 5。
 > — Robin 8-08 精读
 ## Cross-reference
 - **Canonical synthesis:** this page (`/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md`)
 - **Vendor deep-read report:** `/home/ldw/workspace/Liu2026_NBME_shape_conformal_organoid.md`
 - **Wiki.js:** https://wiki.biokingdom.top/zh/literature/liu-2026-nbme-shape-conformal-organoid (Id 1692)
 - **NocoDB row:** 1 in **new table `Robin_Picked_Papers`** (table_id `mbjo0wb56qv1qly`)
 - **SeaFile PDF:** https://fb.biokingdom.top/f/6da50240729e41bdb369/?dl=1
 - **Vendor synthesis pages:** [`/themes/01-organoid-equipment.md`](/themes/01-organoid-equipment.md) (3Brain HD-MEA evidence anchor) + [`/themes/02-bioprinting.md`](/themes/02-bioprinting.md) (Cellink + 3D bioprinting evidence anchor) + [`/commitments.md`](/commitments.md) `liu-2026-hd-mea-roadmap-implication` (vendor-R&D commitment) + [`/open-questions.md`](/open-questions.md) `liu-2026-rogers-lab-vs-3brain-relationship` (vendor relationship question)
 - **New NocoDB table:** `Robin_Picked_Papers` — created 2026-08-08 per Robin instruction; this paper is the first entry
@@ -1,104 +0,0 @@
 ---
 type: "Reference"
 title: "Miao 2025 — co-development of mesoderm and endoderm enables organotypic vascularization in lung and gut organoids (Cell v2)"
 description: "Deep-read synthesis of Miao Y et al. (2025) Cell v2 — single 3D EB co-induction of mesoderm+endoderm yields vHLPO with 7% ECs vs traditional 0%; FOXF1 mutation ACDMPV disease modeling; lung + gut organoid vascularization."
 tags: [literature, deep-read, lung-organoid, gut-organoid, vascularization, mesoderm-endoderm, celvivo-clinostar, 3brain-hd-mea-adjacent]
 ---
 # Miao 2025 — co-development of mesoderm and endoderm enables organotypic vascularization in lung and gut organoids (Cell v2)
 > Miao Y, Pek NM, Tan C et al. | **Cell** | 2025 | DOI: 10.1016/j.cell.2025.05.041 | PMID: 40592324
 > Wiki.js Id 1681 — https://wiki.biokingdom.top/zh/literature/miao-2025-cell-organoid-vascularization-v2
 > NocoDB row 93 in `Organoid_Literature` table
 > SeaFile PDF: https://fb.biokingdom.top/f/24704d54a95941449e2e/?dl=1 (7 figures)
 > Deep-read date: 2026-08-08 (v2); flywheel-sync `flywheel_index` completed 2026-08-08T09:16:07Z
 > Vendor deep-read report: `/home/ldw/workspace/Miao2025_Cell_v2.md`
 **Tags:** lung organoid | gut organoid | vascularization | co-differentiation mesoderm-endoderm | single 3D EB | BMP4 temporal | FOXF1 mutation | ACDMPV disease modeling | decellularized lung scaffold | scRNA-seq | organ-specific endothelium
 ---
 ## 0. Research background and core question
 **Background:** Conventional lung and gut organoid protocols differentiate one germ layer at a time — typically endoderm → lung/gut epithelium with mesoderm added separately. This produces organoids that lack **organotypic vasculature** (no endothelium, no pericytes, no in-vivo functional integration after transplantation). **This study** introduces a **single 3D embryoid body** protocol that **co-induces mesoderm + endoderm simultaneously**, yielding vHLPO (vascularized Human Lung Proximal Organoid) with 7% ECs vs traditional HLPO at 0%.
 **Core questions:**
 - Can a single 3D EB co-induction strategy produce organotypic vasculature in lung and gut organoids?
 - Does the co-differentiation approach yield organ-specific endothelium + mesenchyme, or generic mesoderm?
 - Does in-vivo transplantation of these vascularized organoids produce functional integration with host vasculature?
 - Can FOXF1 mutation (Alveolar Capillary Dysplasia with Misaligned Pulmonary Veins, ACDMPV) be modeled in vHLPO?
 ## 1. Key findings (4-paragraph three-segment format — 4-27 SOP standard)
 ### Key finding 1: Single 3D EB co-induction yields vHLPO with 7% ECs (vs traditional 0%)
 | What was done | What was found | What it means |
 | --- | --- | --- |
 | Day 0-3 BMP4 temporal signal in single 3D EB; Day 3-7 patterning; Day 7-21 organogenesis + vascular maturation | vHLPO 7% ECs (CD31+/CDH5+) vs traditional HLPO 0%; organ-specific endothelium + mesenchyme scRNA-seq confirms identity | **First lung organoid with reproducible organotypic vasculature** — solves the long-standing problem of avascular lung organoids that cannot survive transplantation. The co-induction approach is fundamentally different from adding endothelial cells to a pre-formed epithelium |
 ### Key finding 2: In vivo functional integration with host circulation
 | What was done | What was found | What it means |
 | --- | --- | --- |
 | vHLPO transplanted into immunodeficient mouse kidney capsule | Host vessels anastomose with vHLPO vasculature; human CD31+ vessels perfused with mouse blood; survival >4 weeks | vHLPO is not just in-vitro vascularization — it integrates with host circulation in vivo, opening the door to transplantable organoid therapies and disease modeling with systemic drug exposure |
 ### Key finding 3: FOXF1 mutation ACDMPV modeling — dual pathology validation
 | What was done | What was found | What it means |
 | --- | --- | --- |
 | Patient-derived iPSC with FOXF1 mutation differentiated via the same protocol | Dual pathology: alveolar type II cell defect + misaligned pulmonary veins + reduced vasculature | ACDMPV (a rare neonatal lethal lung disease) reproduces in vHLPO with both epithelial and vascular pathology — first patient-derived organoid model that captures the full ACDMPV phenotype |
 ### Key finding 4: Decellularized lung scaffold + vHLPO forms alveolar-capillary interface
 | What was done | What was found | What it means |
 | --- | --- | --- |
 | vHLPO seeded onto decellularized lung scaffolds and matured 14 days | Alveolar-like structures formed at the scaffold surface; partial alveolar-capillary interface | First proof-of-concept that vascularized organoids + decellularized scaffolds can reconstitute alveolar-capillary architecture — bridges 3D bioprinting (the scaffold) and organoid technology (the cellular component) |
 ## 2. Methodology
 | Step | Content | Key parameters |
 | --- | --- | --- |
 | 1. Co-differentiation | Single 3D EB simultaneously induces mesoderm + endoderm | Day 0-3 |
 | 2. BMP temporal | BMP4 temporal signal decides anterior-posterior axis fate | Day 0-3 |
 | 3. Patterning | Day 3-7 lineage commitment to lung/gut | — |
 | 4. Organogenesis + vascular maturation | Day 7-21 | — |
 | 5. scRNA-seq | Organ-specific endothelium + mesenchyme validation | — |
 | 6. In vivo transplant | Kidney capsule immunodeficient mouse | Survival >4 weeks |
 ## 3. Boundaries / Limitations
 - **BMP temporal signal validated only in this lung/gut model** — not yet confirmed in other organoid types (brain, liver, kidney). Generalizability unknown.
 - **FOXF1 mutation validated in only 1-2 patient iPSC lines** — small n for disease modeling.
 - **Decellularized lung scaffold + vHLPO ≠ complete functional alveolar-capillary interface** — alveolar-like structures formed but gas-exchange function not yet characterized.
 - **Static culture for organoid maturation** — same limitation as Sharma 2026; CelVivo ClinoStar low-shear rotating culture is a candidate route to extend maturation windows.
 ## 4. Product relevance (vendor cross-mapping)
 | Vendor / product | Rating | Evidence |
 | --- | ---: | --- |
 | **CelVivo ClinoStar** | **5** | Co-differentiation depends on 3D EB self-organization in low-shear rotating culture — ClinoStar is the canonical hardware for this protocol. The "static culture regression" boundary applies to the protocol; ClinoStar extends the maturation window |
 | **3Brain HD-MEA** | 4 | vHLPO contains developmentally-competent neural mesenchyme — neural electrophysiology readout would benefit from HD-MEA at the air-liquid interface |
 | **Live-cell metabolic analysis** | 4 | Vascularized vs non-vascularized metabolic flux comparison — Seahorse-class instruments quantify the metabolic benefit of vascularization |
 | **3D bioprinting (decellularized scaffold)** | 3 | Decellularized lung scaffold + vHLPO concept bridges 3D bioprinting (the scaffold) and organoid technology (the cellular component). Cellink BIO X could bioprint scaffolds with controlled porosity |
 | **Patient-derived organoid drug screening** | **5** | FOXF1 mutation ACDMPV modeling full pipeline — first patient-derived organoid model for ACDMPV. Same workflow applies to other rare disease FOXF1-class mutations |
 ## 5. Why this matters for Robin's portfolio
 - **Direct CelVivo ClinoStar ammunition:** the vHLPO protocol requires 3D EB co-induction — ClinoStar is the canonical hardware. This is the **strongest CelVivo ClinoStar product relevance rating (5)** in any of the 3 new flywheel-sync papers.
 - **Patient-derived organoid drug screening pipeline:** FOXF1 ACDMPV modeling is the kind of rare-disease story that opens pharma R&D conversations with Chinese pediatric hospitals and rare disease CDMOs.
 - **Cross-vendor co-marketing:** CelVivo ClinoStar (culture) + Cellink BIO X (decellularized scaffold printing) + 3Brain HD-MEA (functional readout) — three-vendor value chain.
 - **Sales ammunition:** "vHLPO 7% ECs vs traditional HLPO 0%" — vascularized lung organoid is a clinically-meaningful differentiator that no competing 2D / static culture can match.
 ## 6. Forward / 转发语 + 落款
 > Miao 2025 v2 是 lung + gut organoid 血管化首篇 — **single 3D EB 共分化 中-内胚层 → vHLPO 7% ECs vs 传统 HLPO 0%**, FOXF1 突变 ACDMPV 完整建模。CelVivo ClinoStar 是 canonical 硬件 (rating 5), 患者源类器官药筛完整管线建立。
 > — Robin 8-08 精读 v2
 ## Cross-reference
 - **Canonical synthesis:** this page (`/sources/literature-miao-2025-cell-vascularization-v2-deepread.md`)
 - **Vendor deep-read report:** `/home/ldw/workspace/Miao2025_Cell_v2.md`
 - **Wiki.js:** https://wiki.biokingdom.top/zh/literature/miao-2025-cell-organoid-vascularization-v2 (Id 1681)
 - **NocoDB row:** 93 in `Organoid_Literature` table
 - **SeaFile PDF:** https://fb.biokingdom.top/f/24704d54a95941449e2e/?dl=1
 - **Vendor synthesis pages:** [`/themes/01-organoid-equipment.md`](/themes/01-organoid-equipment.md) (CelVivo ClinoStar evidence anchor) + [`/sources/literature.md`](/sources/literature.md) (cross-agent index)
@@ -1,8 +1,7 @@
 ---
 type: "Reference"
 title: "Raji 2026 (hMOs + 3Brain HD-MEA) — 7-27 增补版 (跟 7-01 矩阵集成)"
-description: "Deep-read synthesis of Raji H, Bertoli F, Perez MJ, Lam A, Volpicelli-Daley LA, Deleidi M. 2026 Molecular Psychiatry (Nature 子刊, s41380-026-03667-4, DOI 10.1038/s41380-026-03667-4, IF 11) — human midbrain organoids (hMOs) with WNT modulation, dopaminergic neuron differentiation, bioreactor culture, and 3Brain HD-MEA electrophysiology for Parkinson's disease modeling. 7-01 实战范本 (page 1622) + 7-27 增补版 integrated with 3-paper 3Brain MEA matrix (Raji / Pali / Wei) and 4 product-line complementarity chain (CelVivo ClinoStar + Cellink BIO X + 3Brain HD-MEA + FemtoBiomed CellShot)."
+openwiki_generated: true
 tags: [literature-deep-read, 3brain-hd-mea, midbrain-organoid, parkinson, dopaminergic-neuron, bioreactor, 2026-08-13]
 ---
 # Raji 2026 (hMOs + 3Brain HD-MEA) — 7-27 增补版 (跟 7-01 矩阵集成)
@@ -1,101 +0,0 @@
 ---
 type: "Reference"
 title: "Sharma 2026 — vascularized retinal organoid RGC survival and maturation (Cell Stem Cell)"
 description: "Deep-read synthesis of Sharma K et al. (2026) Cell Stem Cell — transiently vascularized human retinal organoids with RGC 18.2% vs ctrl-RO 1.21% at week 18, W31 ON/OFF/ON-OFF light responses, C3 endothelial monolayer integration strategy."
 tags: [literature, deep-read, retinal-organoid, vascularization, RGC, cell-stem-cell, 3brain-adjacent, celvivo-adjacent]
 ---
 # Sharma 2026 — vascularized retinal organoid RGC survival and maturation (Cell Stem Cell)
 > Sharma K, Habibey R, Ribeiro MM, Cui B, Siwicki RA, Striebel J, Pawlick JS, Zorn J, Utz L, Renner M, Picelli S, Holz FG, Ruiz de Almodóvar C, Cowan CS, Busskamp V. | **Cell Stem Cell** 33:253-271.e13 | 2026 | DOI: 10.1016/j.stem.2025.12.013 | PMID: 41529691
 > Wiki.js Id 1678 — http://10.10.10.254:3000/zh/literature/sharma-2026-cell-stem-cell-vascularized-retinal-organoid-rgc
 > NocoDB row 700 in `Organoid_Literature` table
 > SeaFile PDF: https://fb.biokingdom.top/f/861202f029004d75b456/?dl=1 (7 figures: fig1 4d069beed4c445c59500 / fig2 c3fb945219954ae3907f / fig3 15e0f4ac28c34b369437 / fig4 47517582107e46569f8e / fig5 610aa8efdc7d4407a9d1 / fig6 91d711525355431a9c76 / fig7 35fbb156f3624a5fb15b)
 > Deep-read date: 2026-08-07; flywheel-sync `flywheel_index` completed 2026-08-08T03:19:30Z
 > Vendor deep-read report: `/home/ldw/workspace/retinal_organoid_deep_read_2026-08-07.md`
 **Tags:** retinal organoid | retinal ganglion cell (RGC) | vascularization | endothelial monolayer integration | ETV2.2 hiPSC | PDMS dual-chamber microfluidic | MEA electrophysiology | disease modeling | retinopathy of prematurity (ROP)
 ---
 ## 0. Research background and core question
 **Background:** Human retinal organoids (ROs) are 3D iPSC-derived tissues that recapitulate retinal histogenesis. They contain retinal ganglion cells (RGCs) but lack vasculature — this limits long-term RGC survival and functional maturation in vitro. **This study** introduces a transiently vascularized retinal organoid (vRO) via the C3 strategy (pre-differentiated endothelial cell monolayer integration) and characterizes RGC survival, maturation, and light-response fidelity.
 **Core questions:**
 - Can vascular-like networks be integrated into retinal organoids without disrupting retinal histogenesis?
 - Do vascularized ROs support higher RGC yield and longer functional maturation than non-vascularized controls?
 - Can vROs reproduce retinal light-response physiology (ON / OFF / ON-OFF responses) at week 31?
 ## 1. Key findings (4-paragraph three-segment format — 4-27 SOP standard)
 ### Key finding 1: C3 endothelial monolayer integration gives stable vascular-like network through W16
 | What was done | What was found | What it means |
 | --- | --- | --- |
 | Day 7 EBs onto pre-differentiated ETV2.2 hiPSC-derived endothelial cell monolayer; vRO + ctrl-RO cultured 31 weeks | 72.6% ± 5.4% EB PECAM1+ at week 3; 79.21% ± 6.1% vRO PECAM1+ at week 4; W16 PECAM1+ lumens 41.3% ± 4.19% perfusable by AF-598 dextran | The C3 strategy produces a vascular-like network that **perfuses** through week 16 — establishing a true vascularized retinal organoid model rather than a static endothelial cell co-culture |
 ### Key finding 2: W18 RGC yield 18.2% (vRO) vs 1.21% (ctrl-RO), p<0.001
 | What was done | What was found | What it means |
 | --- | --- | --- |
 | POU4F1+ RGC flow cytometry + scRNA-seq at W18 | 18.2% ± 4.31% (vRO) vs 1.21% ± 0.20% (ctrl-RO), p<0.001; RGC lineage maturation score 52% (vRO) vs 36% (ctrl-RO) | **15× RGC yield improvement** through vascularization — most ctrl-RO RGCs die by W18 without a vasculature to supply nutrients. RGC lineage maturation score also higher in vROs |
 ### Key finding 3: W31 ON/OFF/ON-OFF light responses with high fidelity
 | What was done | What was found | What it means |
 | --- | --- | --- |
 | MEA (Multi Channel Systems MEA2100-Lite, 60 channels, 32 kHz) recording of vRO spontaneous + evoked activity at W17-W31 | W17-W23 vRO spontaneous spiking + synchrony > ctrl-RO; W25 ctrl-RO silent, vRO still recordable; W31 ON/OFF/ON-OFF PSTH amplitudes 69/237/38 (vRO) vs 110/281/53 Hz (ctrl-RO); fidelity >90% (ON/ON-OFF) and 72%/53% (OFF) | vROs maintain activity beyond week 25 (when ctrl-ROs go silent) and reproduce retinal physiology ON / OFF / ON-OFF light-response classes — first retinal organoid model with sustained functional electrophysiology through week 31 |
 ### Key finding 4: ROP disease modeling via hypoxia + CoCl2 + VEGF
 | What was done | What was found | What it means |
 | --- | --- | --- |
 | W12 + 5d 4% O2 + 100 μM CoCl2 + 100 ng/mL VEGF | Neovascular phenotype observed (vessels + aberrant sprouting) | ROP model is reproducible in vROs — provides an in-vitro preclinical platform for retinopathy of prematurity drug screening |
 ## 2. Methodology
 | Step | Content | Key parameters |
 | --- | --- | --- |
 | 1. iPSC line | B7 hiPSC | — |
 | 2. Endothelial | ETV2.2 forward-programmed hiPSC (CD31+) | Pre-differentiation 7d before C3 integration |
 | 3. Integration | C3 strategy: d7 EB onto pre-differentiated EC monolayer | Microfluidic PDMS dual-chamber (5 μm high × 30 μm wide × 1,200 μm long microchannels) |
 | 4. Culture | vRO + ctrl-RO 31 weeks | Static culture (paper notes limitation — see §Boundaries) |
 | 5. MEA | Multi Channel Systems MEA2100-Lite | 60 channels, 32 kHz |
 | 6. Opsin | POU4F1-f-ChRimson-EYFP (optogenetic) + endogenous photoreceptors (W31) | — |
 ## 3. Boundaries / Limitations
 - **Vascular-like network regresses in static culture** — not stable long-term vasculature (a candidate route to extend network stability is low-shear rotating culture, e.g. CelVivo ClinoStar)
 - **scRNA-seq at W18 missed endothelial cluster** — protein-level PECAM1 still visible but transcriptomics underrepresents the vascular compartment
 - **POU4F1 is not RGC-exclusive** — needs orthogonal evidence (e.g. BRN3A, ISL1 co-staining)
 - **60-channel standard MEA** — not HD coverage (3Brain HD-MEA at 4096 electrodes would offer 10-50× spatial resolution for the same recording)
 - **5-day hypoxia + CoCl2 + VEGF model is acute stimulus**, not full ROP pathology
 ## 4. Product relevance (vendor cross-mapping)
 | Vendor / product | Rating | Evidence |
 | --- | ---: | --- |
 | **3Brain HD-MEA** | 4 | Paper uses 60-channel MEA2100-Lite (Multi Channel Systems); 3Brain HD-MEA is same-generation HD technology (4096 electrodes vs 60). Technical route is transferable — Sharma's W31 light-response recording paradigm is the kind of long-duration, multi-class (ON/OFF/ON-OFF) recording where HD spatial resolution matters most |
 | **CelVivo ClinoStar** | 3 | Paper notes vascular-like network regresses in static culture — ClinoStar low-shear rotating culture is the candidate route to extend network stability beyond W16 (vascular network regression is the biggest limitation in the paper) |
 ## 5. Why this matters for Robin's portfolio
 - **Application-domain entry:** retinal organoid is one of the 4 application domains (3D cell culture / 3D bioprinting / neuroscience in vitro / organoid workflows). Robin has only 1 prior retinal deep-read (`Schwab 2025 bioRxiv` 3D-printed bioreactor retinal organoids, 2026-06-28). Sharma 2026 is the **first peer-reviewed retinal organoid paper with vascularization** in Robin's deep-read corpus.
 - **HD-MEA cross-sell:** the paper uses 60-channel MEA, not 3Brain HD-MEA — this is a **vendor-adjacent signal** for "if you want to do Sharma-style retinal recording at higher spatial resolution, use 3Brain Accura-3D + 4096 electrodes".
 - **CelVivo ClinoStar cross-sell:** the paper's #1 limitation (vascular regression in static culture) is exactly the failure mode ClinoStar low-shear rotating culture was designed to fix — strong co-marketing story.
 - **Sales ammunition:** "vRO W18 RGC 18.2% vs ctrl-RO 1.21%" — 15× RGC yield improvement is a clear vendor-adjacent differentiator.
 ## 6. Forward / 转发语 + 落款
 > Sharma 2026 是 retinal organoid 血管化首篇 — **W18 RGC 18.2% vs ctrl-RO 1.21% (15×)**, W31 ON/OFF/ON-OFF 光响应保真度 >90%。技术栈 (60-channel MCS MEA2100-Lite + 静态培养) 是 3Brain HD-MEA + CelVivo ClinoStar 的天然升级路径 — retinal organoid 是 Robin portfolio 里缺位的赛道。
 > — Robin 8-08 精读
 ## Cross-reference
 - **Canonical synthesis:** this page (`/sources/literature-sharma-2026-cell-stem-cell-vascularized-retinal-organoid-rgc-deepread.md`)
 - **Vendor deep-read report:** `/home/ldw/workspace/retinal_organoid_deep_read_2026-08-07.md`
 - **Wiki.js:** http://10.10.10.254:3000/zh/literature/sharma-2026-cell-stem-cell-vascularized-retinal-organoid-rgc (Id 1678)
 - **NocoDB row:** 700 in `Organoid_Literature` table
 - **SeaFile PDF:** https://fb.biokingdom.top/f/861202f029004d75b456/?dl=1
 - **Vendor synthesis pages:** [`/themes/01-organoid-equipment.md`](/themes/01-organoid-equipment.md) (3Brain HD-MEA evidence anchor) + [`/sources/literature.md`](/sources/literature.md) (cross-agent index)
@@ -1,8 +1,7 @@
 ---
 type: "Reference"
 title: "3D 打印缓释 HCTZ 片: 跟 Cellink BIO X 挤出打印 (Tasevska 2025 EJPS)"
-description: "Deep-read synthesis of Tasevska T et al. 2025 European Journal of Pharmaceutical Sciences 206:106998 (DOI 10.1016/j.ejps.2024.106998, 精读 2026-07-27) — first systematic SSE semi-solid extrusion vs DLP digital-light-processing comparison for sustained-release HCTZ (hydrochlorothiazide) tablets, with focus on SSE matching Cellink BIO X extrusion principle. Supports Robin's 3D-printed personalized-dose / sustained-release positioning and SSE extruder cross-sell narrative for Cellink BIO X accounts."
+openwiki_generated: true
 tags: [literature-deep-read, cellink-bio-x, 3d-printing, HCTZ, sustained-release, SSE, DLP, 2026-08-13]
 ---
 # 3D 打印缓释 HCTZ 片: 跟 Cellink BIO X 挤出打印 (Tasevska 2025 EJPS)
@@ -1,484 +1,107 @@
 ---
 type: "Reference"
-title: "Literature Deep-Reads — cross-agent deep-read index"
+title: "Literature Deep-Reads — 跨 agent 精读索引"
 openwiki_generated: true
 ---
-## Zhu 2025 Adv Sci - 类器官 + 个体化 CAR-γδ T cocktail 治疗异质性 GBM (2026-09-28)
+# Literature Deep-Reads — 跨 agent 精读索引
- **DOI**: 10.1002/advs.202503311
+> 数据源: Obsidian vault `04-Literature/Deep-Reads/<vendor>/<DOI>.md` (git-repo connector 自动同步)
- **期刊**: Advanced Science (IF 16.9)
+> 用途: MiniMax code / Hermes 跨 agent 检索 "Robin 最近精读了什么文献"
- **作者**: Zhu G et al. (山东大学王成伟团队)
+> 更新: OpenWiki cron 每天 02:00 自动扫 vault mtime, 增量更新本文件
 - **类器官**: CelVivo ClinoReactor 25 rpm 旋转培养 ≥15 d
 - **核心发现**: Vδ1 γδ T 介导三 CAR cocktail (B7-H3+IL-13Rα2+GD2) 杀伤率 85-92%, 缺氧浸润 380 μm vs αβ 75 μm
 - **Wiki.js**: https://wiki.biokingdom.top/zh/literature/zhu-2025-adv-sci-glioblastoma-organoid-cocktail-car-gdelt (Page 1815)
 - **NocoDB**: CelVivo_Literature Id 117
 - **PDF**: https://fb.biokingdom.top/api/v4/file/content/43ywuL/0/zhu2025_advsci_glioblastoma.pdf (13 MB)
 - **报告路径**: /home/ldw/桌面/类器官工坊/精读文献库/2026/Zhu 2025 - 类器官CAR-γδ T cocktail GBM治疗 (Adv Sci).md
---
+## 最近 30 天精读 (按 mtime 倒序)
 type: "Reference"
 title: "Literature Deep-Reads — cross-agent deep-read index"
 description: "Cross-agent index of Robin's literature deep-reads across the 4 vendor product lines (CelVivo / 3Brain / Cellink / Femtobiomed) and adjacent application domains (organoid IRB / ethics, vascularized organoids, microfluidic / organ-on-chip, brain-organoid ALI oxygen engineering, HGSC ovarian cancer precision medicine). Backed by the Obsidian vault 04-Literature/Deep-Reads/ and the flywheel-sync pipeline; synthesis pages are linked per paper. The 2026-09-11 fetch added 2 new entries after the **vault silence streak was broken** at 2026-09-10 (Tomas 2026 HGSC + Vijakumaran 2026 brain-organoid ALI oxygen engineering, the latter being the **first v4 Flywheel auto-sink pipeline entry**); the prior 2026-08-31 CelVivo cluster remains the most-recent vault activity for 11 calendar days before the 2026-09-10 / 2026-09-11 resumption."
 tags: [literature, deep-read, flywheel, celvivo, 3brain, cellink, femtobiomed, tevonian-2026-vascularized-liver-mps, yang-2026-cardiac-organoid-review, shen-2026-vascularized-organoids-review, zhai-2026-3d-skin-pemphigus, yan-2024-tmem106b-sars-cov2-brain-organoid, stewart-2023-ba5-xbb-neurotropic-brain-organoid, nguyen-2024-jev-g4-australia-brain-organoid, aiello-2025-brain-organoid-reproducibility, miao-2025-vascularized-lung-gut-organoids, pasca-2025-nature-assembloid, microgravity-reproductive-review-2026, tomas-2026-hgsoc-parpi-spheroid-organoid, vijakumaran-2026-brain-organoid-ali-oxygen-engineering, 2026-09-11, 2026-09-10, 2026-08-31, 2026-08-27, 2026-08-25, 2026-08-24, 2026-08-23, vascularized-organoids, cardiac-organoids, skin-organoids, brain-organoid-virology-cluster, third-5paper-burst, celvivo-capital-v-parallel-subfolder, flywheel-v4-auto-sink, vault-silence-broken, vault-resumed-after-11d, post-celvivo-burst-cluster-resumption]
 timestamp: 2026-09-11T18:14:00Z
 ---
 # Literature Deep-Reads — cross-agent deep-read index
 > Source: Obsidian vault `04-Literature/Deep-Reads/<vendor>/<DOI>.md` (git-repo connector auto-sync) + flywheel-sync `~/.hermes/data_sources/literature_flywheel.jsonl` for pipeline status.
 > Purpose: allow MiniMax code / Hermes cross-agent retrieval of "what has Robin recently deep-read".
 > Update: git-repo-1 2026-08-24 18:05 UTC — **5-paper root-level LDR burst** (CelVivo App Note + Aiello + Tian + Kim + Ajongbolo) — the largest single-day cluster since 2026-07-29; all 5 files landed at `04-Literature/Deep-Reads/` root (non-standard pattern vs the prior per-vendor subfolder discipline). Previous flywheel-sync (2026-08-08) completed `flywheel_index` on 3 papers (Sharma 2026 Cell Stem Cell, Miao 2025 Cell v2, Liu 2026 Nat Biomed Eng) — see entries below.
 ## Last 30 days of deep reads (mtime descending)
 ### 2026-09-12 (colorectal neuroendocrine-neoplasm PDO+PDOX BRAF/MEK — non-vendor, PMC gold OA)
 | DOI | Vendor | Application | Title (short) | Vault path |
 | --- | --- | --- | --- | --- |
 | `10.1210/jendso/bvag196` | **none — 0 product mentions** (Matrigel static) | Rare colorectal NEN: 3 PDO lines (37.5%), WES/RNA-seq fidelity, BRAF-mutant BRAF/MEK combo | Chen et al 2026 J Endocr Soc bvag196 (PMID 42694446; PMC13538959; Wiki 1790) — combo IC50 dabrafenib 3.766→0.505µM; PDOX TGI 66.27% (P=.021) | `obsidian-vault/04-Literature/Deep-Reads/chen-2026-crc-neuroendocrine-neoplasm-organoid-braf.md` |
 ### 2026-09-11 (Vijakumaran 2026 brain-organoid ALI oxygen engineering — first v4 Flywheel auto-sink pipeline entry)
 | DOI / slug | Vendor | Application | Title (short) | Vault path |
 | --- | --- | --- | --- | --- |
 | `vijakumaran2026-brain-organoid-ali-oxygen-engineering` | **TBD — vendor callout pending** (path is `Literature/Deep-Reads/Organoid/`, suggesting Robin classified it under brain-organoid culture-technique domain; NocoDB Id=3029; vendor mapping pending Tavily verification) | Brain organoid air-liquid interface (ALI) oxygen engineering | Vijakumaran 2026 **Air-liquid interface-centered oxygen engineering in human brain organoids** (NocoDB Id=3029; Wiki ID TBD; **first paper routed through the v4 Flywheel auto-sink pipeline** per the `09bec367` commit message `飞轮 v4 自动 sink`) — air-liquid interface (ALI) culture technique applied to human brain organoids to control oxygen exposure for neural maturation; the ALI-centered oxygen engineering pattern is structurally adjacent to CelVivo ClinoReactor (long-term stable oxygen-controlled organoid culture) + 3Brain HD-MEA (downstream functional validation via electrophysiology) + Mimetas OrganoPlate (ALI culture is the canonical Mimetas OrganoPlate use case for airway / lung / intestinal epithelia, now applied to brain organoid) — vendor-mapping step pending | `obsidian-vault/Literature/Deep-Reads/Organoid/vijakumaran2026-brain-organoid-ali-oxygen-engineering.md` |
 ### 2026-09-10 (HGSC ovarian-cancer PDO combination-therapy deep-read — non-vendor, PMC gold OA — vault commit landed 2026-09-10)
 | DOI | Vendor | Application | Title (short) | Vault path |
 | --- | --- | --- | --- | --- |
 | `10.1080/15384047.2025.2611602` | **none — 0 product mentions** (spheroid = ULA static plate; organoid = Cultrex BME; no bioreactor/spinner) | HGSC patient-ascites iOvCa lines (n=6) as spheroids + organoids; carboplatin ± olaparib/niraparib direct vs sequential | Tomas EJ, Davis J, Ramos Valdes Y, Shepherd TG (2026) **Evaluating carboplatin and PARP inhibitor combination efficacy using high-grade serous carcinoma spheroids and organoids** (Cancer Biol Ther 27(1):2611602; Western University; PMID 41520277; PMC12795296 gold OA; Wiki.js 1787; **vault commit `1fd63019` 2026-09-10 — first vault commit since the 2026-08-31 CelVivo cluster**) — direct combination did NOT exceed carboplatin alone (no additivity/synergy); only exception = BRCA1-mutant iOvCa195 organoids benefit when PARPi given FIRST; niraparib more potent than olaparib except iOvCa256 (27.16 vs 18.09 µM); RAD51 foci functional HRD validation. Key "honest negative" for clinical-trial sequencing of PARPi-before-chemo in HRD patients | `obsidian-vault/04-Literature/Deep-Reads/tomas-2026-hgsoc-carboplatin-parpi-spheroid-organoid.md` |
 ### 2026-08-31 (5-paper CelVivo-anchored single-shot LDR burst — NEW `CelVivo/` capital-V subfolder)
 | DOI | Vendor | Application | Title (short) | Vault path |
 | --- | --- | --- | --- | --- |
 | `10.3389/fmicb.2023.1320856` | **CelVivo ClinoStar** (direct platform) | SARS-CoV-2 omicron BA.5/XBB neurotropic brain organoids (K18-hACE2 mice + human brain organoids) | Stewart R, Yan K, Ellis SA et al. (2023) **SARS-CoV-2 omicron BA.5 and XBB variants have increased neurotropic potential over BA.1 in K18-hACE2 mice and human brain organoids** (Front Microbiol 14:1320856; QIMR Berghofer Medical Research Institute + University of Queensland; first file in NEW `CelVivo/` capital-V subfolder) — BA.5/XBB variants have increased neurotropic potential vs BA.1; MA1 infection cell count higher in human brain organoids (CelVivo ClinoStar); companion to Yan 2024 + Nguyen 2024 in the QIMR Berghofer Suhrbier/Rawle viral-neurotropism brain-organoid trio | `obsidian-vault/04-Literature/Deep-Reads/CelVivo/stewart-2023-ba5-xbb-neurotropic-brain-organoids.md` |
 | `10.1038/s44319-025-00619-x` | **CelVivo ClinoStar/ClinoReactor** ⭐⭐⭐⭐⭐ (CelVivo ApS is a co-author) | Brain organoid reproducibility via controlled fluid dynamics | Aiello G, Nemir M, Vidimova B, Ramel C, Viguie J, Ravera A, Wrzesinski K*, Bagni C* et al. (2025) **Increased reproducibility of brain organoids through controlled fluid dynamics** (EMBO reports 26:6209-6239; 洛桑大学 + 罗马 Tor Vergata 大学 + 西北大学 (南非) + **CelVivo ApS (丹麦) co-author**; second file in NEW `CelVivo/` capital-V subfolder) — **CV <15% morphological consistency** vs static culture CV >30% across multi-batch + multi-iPSC-line brain organoid cultures + scRNA-seq OXPHOS metabolic profiling + cortical cell type recapitulation (SOX2/Nestin/PAX6 + DCX + TBR1/SATB2/MAP2 multi-marker IHC). The CelVivo ApS co-author affiliation is the **first direct CelVivo-platform co-authored deep-read** in Robin's set | `obsidian-vault/04-Literature/Deep-Reads/CelVivo/aiello-2025-brain-organoid-reproducibility.md` |
 | `10.1038/s44298-024-00025-5` | **CelVivo ClinoStar** (direct platform) | Japanese Encephalitis virus genotype 4 isolate characterization (2022 Australian outbreak) + brain organoids | Nguyen W, Gyawali N, Stewart R, Tang B, Cox AL, Yan K, Larcher T, Bishop CR, Wood N, Devine GJ, Suhrbier A, Rawle DJ (2024) **Characterisation of a Japanese Encephalitis virus genotype 4 isolate from the 2022 Australian outbreak** (npj Viruses 25; QIMR Berghofer + INRAE; third file in NEW `CelVivo/` capital-V subfolder) — JEV G4 isolate from 2022 Australian outbreak; brain organoid CelVivo ClinoStar + mouse model; extends the QIMR Berghofer Suhrbier/Rawle viral-neurotropism brain-organoid line into the flavivirus (JEV) application domain. JEV is endemic in 东南亚 + 中国南方 + 西太平洋 — directly relevant to Chinese infectious-disease R&D customer base | `obsidian-vault/04-Literature/Deep-Reads/CelVivo/nguyen-2024-jev-g4-2022-australia-brain-organoids.md` |
 | `10.1016/j.cell.2025.05.041` | **CelVivo ClinoReactor** ⭐⭐⭐⭐⭐ (direct platform validation as co-differentiation + vascularization standard) | Co-development mesoderm+endoderm for organotypic vascularization in lung and gut organoids | Miao Y, Pek NM, Tan C, Chen Y-W, Guo M*, Gu M* (2025) **Co-development of mesoderm and endoderm enables organotypic vascularization in lung and gut organoids** (Cell 188:1-19; 8-08 精简版已升级完整版; fourth file in NEW `CelVivo/` capital-V subfolder) — companion to the 2026-08-08 flywheel-sync Miao 2025 v2 deep-read (`/home/ldw/workspace/Miao2025_Cell_v2.md`); the **Cell published version** extends the v2 deep-read with the canonical CelVivo ClinoReactor co-differentiation mesoderm+endoderm platform + scRNA-seq single-cell profiling of FOXF1 endothelial-mesenchymal transition | `obsidian-vault/04-Literature/Deep-Reads/CelVivo/miao-2025-vascularized-lung-gut-organoids.md` |
 | `10.1016/j.celrep.2024.114921` | **CelVivo ClinoStar** (direct platform) | TMEM106B-mediated SARS-CoV-2 ACE2-independent brain organoid infection | Yan K, Dumenil T, Stewart R, Bishop CR, Nguyen W, Suhrbier A*, Rawle DJ* (2024) **TMEM106B-mediated SARS-CoV-2 infection allows for robust ACE2-independent infection in vitro but not in vivo** (Cell Reports 43:114921; QIMR Berghofer Medical Research Institute; fifth file in NEW `CelVivo/` capital-V subfolder) — CRISPR 筛选鉴定 **TMEM106B / 硫酸乙酰肝素 / 内吞介导 ACE2 非依赖进入** in human cortical brain organoids (CelVivo ClinoStar); MA1 神经毒力更强 in vitro (滴度更高 / 感染细胞更多) + K18-hACE2 小鼠疾病更重 / 生存率更低; **in vivo 不成立**: wild-type / Ifnar-/- 小鼠无增加神经侵袭 + Ace2-/- 小鼠肺无法感染. Companion to Stewart 2023 + Nguyen 2024 in the QIMR Berghofer Suhrbier/Rawle viral-neurotropism trio | `obsidian-vault/04-Literature/Deep-Reads/CelVivo/yan-2024-tmem106b-sars-cov2-ace2-independent.md` |
 ### 2026-08-23 (5-paper single-shot LDR burst — vault root, non-standard pattern)
 | DOI / slug | Vendor | Application | Title (short) | Vault path |
 | --- | --- | --- | --- | --- |
 | `CelVivo_AppNote_2026` | **CelVivo (ClinoStar vs Orbital Shaker direct comparison)** | Low shear stress + cytoskeletal integrity for 3D constructs (HepG2/C3A 15d + embedded Caco-2 + brain organoid) | Stougaard Borgen Løschenkohl + Sedighi Frandsen, **CelVivo Application Note 2026** (sourced from RAGFlow CelVivo KB 1555e5b2, Robin 8-24 上传; Wiki.js 1747) — head-to-head **ClinoStar vs orbital shaker** comparison: ClinoStar preserves F-actin organization + cytoskeletal integrity + tight cellular cohesion vs orbital shaker's dispersed F-actin + loose morphology + reduced cohesion (phalloidin/DAPI dual-magnification 4x + 20x); 15-day standardized workflow with 3 bio-replicates; multi-model transferability across HepG2/C3A + embedded Caco-2 + brain organoid. **Canonical ClinoStar vs-orbital-shaker competitive-killer document**; Robin's first vendor App Note deep-read | `obsidian-vault/04-Literature/Deep-Reads/CelVivo_Shear_Stress_AppNote_2026.md` |
 | `biorxiv_Aiello_Bagni_2025_RC_CFD` | **CelVivo (ClinoStar-adjacent — RC = ClinoStar simplified geometry)** + 3Brain (cortical organoid e-phys, adjacent) | CFD-quantified low shear stress Rotating Chamber for brain organoid | Aiello F, Bagni C et al. (2025) **biorxiv preprint** (the EMBO Reports submission version `Aiello_Bagni_EMBO R_050325`, Robin 8-24 从 CelVivo KB 找到的 PDF; Wiki.js 1746) — **first CFD-quantified Rotating Chamber (RC) study**: cavity geometry Ø 37.7 mm × H 8.8 mm; **COMSOL Multiphysics 6.2 shows cavity shear stress < 20 mPa** (extremely low); multi-density 1010/1020/1030 vs medium 1000 confirms shear-stress uniformity; morphological CV < 15% vs static culture CV > 30% across batches + cell lines; cortical cell type recapitulation (SOX2/Nestin/PAX6 + DCX + TBR1/SATB2/MAP2 multi-marker IHC) + scRNA-seq OXPHOS metabolic profiling. **The < 20 mPa quantitative number is direct ammunition** for the existing ClinoStar vendor-positioning pitch | `obsidian-vault/04-Literature/Deep-Reads/Aiello_Bagni_2025_biorxiv_Brain_Organoid_Fluid.md` |
 | `10.1038/s41467-025-60934-8` | (no vendor callout — cardiac application-domain) | hiPSC epicardium mTOR-driven maturation + paracrine cardiomyocyte cross-talk | Tian Y, Lucena-Cacace A, Tani K et al. (2025) **Generation of mature epicardium derived from human-induced pluripotent stem cells via inhibition of mechanistic target of rapamycin** (Nat Commun; Wiki.js 1745) — **Torin1 (dual mTORC1/2 inhibitor, 200 nM) drives hiPSC epicardium maturation**: mature markers (TJP1/WT1/TBX18/ALDH1A2/CDH18) up + EMT markers (SNAI1/SNAI2/CDH2/CDH1) down + proliferation markers (MKI67/PCNA/MCM2) down + fatty-acid metabolism maturation (PDK4/PPARGC1A/SIRT1/FASN/SREBF1); 379 DEGs; adult-like profile vs GSE84085; YBX3 + MAFF identified as Torin1-specific TFs; **paracrine TNNI3 upregulation in hiPSC ventricular cardiomyocyte EBs co-cultured for 10 days**. **First cardiac-epicardium paper in Robin's deep-read set** | `obsidian-vault/04-Literature/Deep-Reads/Tian_2025_NatCommun_Epicardium_mTOR.md` |
 | `10.1038/s41467-024-55752-3` | **3Brain (HD-MEA competitor / adjacent paper — 3rd next-gen HD-MEA approach)** | EGaIn liquid-metal 3D MEA + magnetically reshapable + cortical organoid electrophysiology | Kim E, Jeong E, Hong YM et al. (2025) **Magnetically reshapable 3D multi-electrode arrays of liquid metals for electrophysiological analysis** (Nat Commun; Wiki.js 1744) — microfluidic direct-ink-writing EGaIn 3D pillar MEA with **pillar height 25-310 μm (R² > 0.95, n=12)** + **pillar diameter 14 μm** (single-neuron scale) + parylene-C selective encapsulation; **Ni magnetic layer for magnetic reshape** → shape conforms to different organoid sizes; hPSC cortical organoid maturation 15/30/45/60/120 days → 6-marker co-expression (MAP2/GFAP/VGLUT1/SATB2/CTIP2) = cortical 6-layer-like structure; biocompatible 4-month organoid + 3D MEA co-culture 14d; 64-channel MEA single-unit spike + network synchronization. **3 distinct next-gen HD-MEA approaches now in Robin's deep-read set**: Liu 2026 Rogers Lab flexible-electronics framework + Kim 2025 EGaIn 3D pillar + 3Brain Accura-3D rigid CMOS | `obsidian-vault/04-Literature/Deep-Reads/Kim_2025_NatCommun_Liquid_Metal_3D_MEA.md` |
 | `10.3390/cells14110842` | **CelVivo (ClinoStar-adjacent) + 3Brain (HD-MEA-adjacent)** | Brain organoid + assembloid review (disease modeling + drug discovery) | Ajongbolo AO, Langhans SA (2025) **Brain Organoids and Assembloids—From Disease Modeling to Drug Discovery** (Cells; Wiki.js 1743) — **canonical brain organoid + assembloid review**: 3-tier taxonomy (whole-brain → region-specific → complex systems); 4-class characterization methodology (morphological + biochemical + functional + omics); disease-modeling boundaries (neurodevelopmental / neurodegenerative / brain-tumor); drug-discovery HTS pipeline (96-well + microfluidic + automated imaging + AI phenotype). **First comprehensive brain-organoid review** in Robin's deep-read set since the 2026-07-29 Organoids 2026 review — pairs with that review to anchor the brain-organoid review lane | `obsidian-vault/04-Literature/Deep-Reads/Ajongbolo_2025_Cells_Brain_Organoids_Review.md` |
 ### 2026-08-16 (Quintard 2024 + Guo 2026 — 2 papers on the same day)
 | DOI | Vendor | Application | Title (short) | Vault path |
 | --- | --- | --- | --- | --- |
 | `10.1038/s41467-024-45710-4` | CelVivo (ClinoStar rating 3 upstream) + Mimetas OrganoPlate (rating 4 direct) + Emulate Organ-Chip (rating 3) | Microfluidic platform for vascularized organoids | Quintard C et al. (2024) A microfluidic platform integrating functional vascularized organoids-on-chip (Nat Commun; 10 通道并行微流控芯片 + U 型捕获位 + hiPSC-BVO 30 天功能性灌注培养 + 跨类器官验证 [间充质球体 / BVO / 胰岛球体 / 肺类器官]; 血管层级化 37 µm 上游动脉-静脉 + 8 µm BVO 毛细管, 壁剪切 27-2000 s⁻¹ 完美匹配人体毛细血管生理范围 50-1900 s⁻¹) — Wiki.js IDs 1719/1720/1722, NocoDB Id 3297; 4-commit LDR cycle 2026-08-16 (`0fc8db24` → `290e9635` → `24c713de` → `4073abf4`); last commit deleted the 3Brain reference per the SOP "硬门槛合规修正" cleanup rule | `obsidian-vault/Literature/Deep-Reads/Organoid/quintard_2024_vasorganoid_chip.md` |
 | `10.3389/fcell.2026.1721946` | CelVivo (ClinoStar rating 4 clinical-translation IRB) + Mimetas OrganoPlate (rating 4 co-culture ethics) + Emulate Organ-Chip (rating 3) | Organoid research IRB / ethics systematic review | Guo Z & Zhang N (2026) Ethical review key considerations for organoid applications in biomedical research—a systematic review (Front Cell Dev Biol; 嘉兴市第一医院 + 嘉兴大学医学院视角; 类器官研究 IRB / 伦理审查 7 大强制要点系统综述 [样本来源/知情同意/数据隐私/共培养主体性/3R 动物福利/跨境监管/长期保存与终止使用] + 5 国对照 [中国《人类遗传资源管理条例》+《涉及人的生命科学和医学研究伦理审查办法》2023 / 美国 HIPAA + Common Rule + NIH GDS / 欧盟 GDPR + Clinical Trials Regulation 536/2014 / 日本 / 韩国]) — Wiki.js ID 1724, NocoDB Id 3298; 3-commit LDR cycle 2026-08-16 (`2e6f5989` → `00f824f2` → `a4fa5a32`); Robin translated the paper into a customer-facing IRB application checklist template at `templates/类器官IRB申请清单.md` v1.0 (180 lines; 7 mandatory points + 5 customer Q&A + China vs International flow + 10 attachments + 7 citations) | `obsidian-vault/Literature/Deep-Reads/Organoid/guo_2026_organoid_ethical_review.md` |
 ### 2026-08-09
 | DOI | Vendor | Application | Title (short) | Vault path |
 | --- | --- | --- | --- | --- |
 | `10.7150/thno.90492` | Microfluidic chip system + 类器官培养试剂 + 高内涵成像 + 单细胞与空间组学 (4 类共性硬件) | Organoid-on-Chip 综述 / 类器官 + 器官芯片协同平台 / 血管化、疾病建模、精准医学 | Wang H, Ning X, Zhao F, Zhao H, Li D. (2024) Human organoids-on-chips for biomedical research and applications (Theranostics 14(2):788-818, PMID 38169573; 7 图覆盖 7 大主题板块: OOCs/HOs/OrgOCs 架构 + 器官发育/血管化/免疫/器官通讯/疾病建模/精准医学; PMCID PMC10758054) — NocoDB row 3295 in `Organoid_Literature`, Wiki.js ID 1700 (v2 - grp:3 ghost page 累加) | `04-Literature/Deep-Reads/wang2024-org-on-chip.md` |
 ### 2026-08-08 (4 papers — flywheel-sync completed today)
 | DOI | Vendor | Application | Title (short) | Vault path |
 | --- | --- | --- | --- | --- |
 | `10.1038/s41551-026-01620-y` | 3Brain (HD-MEA) + Cellink (microlattice) | Neural organoid e-phys drug screen | Liu N et al. (2026) Shape-conformal porous frameworks for full coverage of neural organoids and high-resolution electrophysiology (Nat Biomed Eng, Rogers Lab; >90% surface coverage vs 5-15% MEA; 3000-8000 channels per organoid; weeks-long stable recording; epilepsy/AD modeling) — first entry in NocoDB table `Robin_Picked_Papers` | `Liu2026_NBME_shape_conformal_organoid.md` (in `/home/ldw/workspace/`) |
 | `10.1016/j.cell.2025.05.041` | CelVivo (ClinoStar) + 3Brain (HD-MEA adjacent) | Lung/gut organoid vascularization | Miao Y et al. (2025) Co-development of Mesoderm and Endoderm Enables Organotypic Vascularization in Lung and Gut Organoids (Cell; vHLPO 7% ECs vs traditional HLPO 0%; single 3D EB co-induction of mesoderm+endoderm; FOXF1 mutation ACDMPV modeling) — NocoDB row 93 in `Organoid_Literature` | `Miao2025_Cell_v2.md` (in `/home/ldw/workspace/`) |
 | `10.1016/j.stem.2025.12.013` | 3Brain (HD-MEA, adjacent) + CelVivo (ClinoStar, adjacent) | Retinal ganglion cell / vascularized retinal organoid | Sharma K et al. (2026) Retinal ganglion cell survival and functional maturation in transiently vascularized human retinal organoids (Cell Stem Cell 33:253-271.e13, PMID 41529691; C3 endothelial integration strategy; W18 POU4F1+ RGC 18.2% vs 1.21% p<0.001; W31 ON/OFF/ON-OFF light responses >90%/72%/53% fidelity) — NocoDB row 700 in `Organoid_Literature` | `Retina-StemCell/literature-sharma-2026-cell-stem-cell-vascularized-retinal-organoid-rgc.md` (planned) |
 | `10.3389/fbioe.2026.1854988` | CelVivo (ClinoStar adjacent) + Cellink (BIO X adjacent) + FemtoBiomed (CellShot adjacent) | Microbioreactor design for eukaryotic cell-based biomedical applications | Rosero G et al. (2026) Microbioreactor design for eukaryotic cell-based biomedical applications (Front Bioeng Biotechnol, Mini Review; 6x productivity vs T-flask; organoid size 140% vs static control; 4 applications: CAR-T / mAb / iPSC / organoid) — NocoDB: `Robin_Picked_Papers` (PMID 42516424, Wiki.js ID 1696) | `Microbioreactor_2026_Rosero_FrontBioeng.md` (in `/home/ldw/workspace/`) |
 ### 2026-08-08 (Fernandez Vallone 2026 — untracked, deep-read commit `6c16dc05` + `d7df3830`)
 | DOI | Vendor | Application | Title (short) | Vault path |
 | --- | --- | --- | --- | --- |
 | `10.3390/cells15110963` | CelVivo (ClinoStar adjacent) + 3Brain (HD-MEA adjacent) | hiPSC brain organoid Thyroid Hormone System Disrupting Chemicals (THSDC) platform | Fernandez Vallone V et al. (2026) Comparative Evaluation of hiPSC-Derived Brain Organoids as Platforms for Assessing Thyroid Hormone System Disrupting Chemicals (Cells 15:963, PMID 42274556; COs vs NSCOs; LC-MS/MS T3代谢; qRT-PCR HR/KLF9/DIO3/SEMA3C; HCA; THSDC = iopanoic acid + silychristin) — NocoDB row 3263 in `Robin_Picked_Papers`, Wiki.js Id 1698, v2 (5 张真图 + 双 H1) | `obsidian-vault/04-Literature/Deep-Reads/Cells/fernandez-vallone-2026-thsdc-brain-organoids.md` |
 ### 2026-08-06 (Parfitt 2024 Nat Commun — untracked deep-read, hiPSC midbrain organoid DJ1 LOF PD model)
 | DOI | Vendor | Application | Title (short) | Vault path |
 | --- | --- | --- | --- | --- |
 | `10.1038/s41467-024-44732-2` | CelVivo (ClinoStar adjacent) + 3Brain (HD-MEA adjacent) | DJ1 LOF / midbrain organoid / Parkinson disease model | Parfitt GM et al. (2024) DJ1 缺失破坏星形胶质溶酶体蛋白降解，引发中脑类器官蛋白稳态崩溃（Nat Commun 15:1071, PMID 38200091; DJ1 KO + L166P 突变 iPSC hMIDOs; 星形胶质 α-synuclein 旁分泌毒性放大 DA 神经元死亡) | `04-Literature/Deep-Reads/Brain/2026-08-06_Parfitt_GM_et_al_NatCommun_2024_DJ1_LOF_midbrain_organoid_PD.md` |
 ### 2026-07-29
-
+| DOI | Vendor | 类器官 | 标题 | 路径 |
-| DOI | Vendor | Application | Title (short) | Vault path |
+|---|---|---|---|---|
-| --- | --- | --- | --- | --- |
+| `10.1186_s40164-026-00743-x` | (无 vendor, 综述) | 全谱综述 | Organoids for disease modeling and treatment: state-of-the-art (Exp Hematol Oncol 2026, PMID 41545895, 190 项临床试验 + 4 大瓶颈) | `Organoid/2026-07-29_Organoids_disease_modeling_treatment_2026_review.md` |
 | `10.1186_s40164-026-00743-x` | (no vendor, review) | Whole-organoid landscape | Organoids for disease modeling and treatment: state-of-the-art (Exp Hematol Oncol 2026, PMID 41545895, 190 clinical trials + 4 bottlenecks) | `Organoid/2026-07-29_Organoids_disease_modeling_treatment_2026_review.md` |
 ### 2026-07-28
-
+| DOI | Vendor | 类器官 | 标题 | 路径 |
-| DOI | Vendor | Application | Title (short) | Vault path |
+|---|---|---|---|---|
-| --- | --- | --- | --- | --- |
+| `10.1080_17460751.2025.2572177` | Ronawk Bio-Block (KB 0 命中) | MSC / 脂肪源 | Comparison of 3D culture systems on MSC longevity, regenerative potential, and secretome production | `RegenMed/2026-07-28_Hodge_2025_RegenMed_MSC_3D_Bio-Block.md` |
-| `10.1080_17460751.2025.2572177` | Ronawk Bio-Block (KB 0 hit) | MSC / adipose source | Comparison of 3D culture systems on MSC longevity, regenerative potential, and secretome production (Hodge 2025) | `RegenMed/2026-07-28_Hodge_2025_RegenMed_MSC_3D_Bio-Block.md` |
+| `10.3389/fvets.2025.1500267` | (无 vendor) | 犬脂肪 MSC 3D 球体 | Lee E et al. (2025) Enhanced immunomodulatory effects of canine adipose tissue-derived mesenchymal stem cells in 3D culture (Front Vet Sci 12:1500267, ULA 板 48h, 3D CM 显著压低 LPS-DH82 M1 p<0.0001) | `Other/2026-07-28_Lee_2025_FrontVetSci_canine_MSC_3D_spheroid.md` |
 | `10.3389/fvets.2025.1500267` | (no vendor) | Canine adipose MSC 3D spheroid | Lee E et al. (2025) Enhanced immunomodulatory effects of canine adipose tissue-derived mesenchymal stem cells in 3D culture (Front Vet Sci 12:1500267, ULA plate 48h, 3D CM significantly suppresses LPS-DH82 M1 p<0.0001) | `Other/2026-07-28_Lee_2025_FrontVetSci_canine_MSC_3D_spheroid.md` |
 ### 2026-07-17
-
+| DOI | Vendor | 类器官 | 标题 | 路径 |
-| DOI / slug | Vendor | Application | Title (short) | Vault path |
+|---|---|---|---|---|
-| --- | --- | --- | --- | --- |
+| `260528_appnote` | CelVivo | 通用 | Influence of shear stress on long-term 3D construct performance: Comparison of orbital shaker and ClinoStar system (vs 竞品杀手文档) | `Celvivo/260528_CS_versus_OS_appnote_2026-07-17.md` |
-| `260528_appnote` | CelVivo | Generic | Influence of shear stress on long-term 3D construct performance: Comparison of orbital shaker and ClinoStar system (vs-competitor killer document) | `Celvivo/260528_CS_versus_OS_appnote_2026-07-17.md` |
+| `111_appnote` | CelVivo | 球体量化 | Planimetry measurements of spheroids in a ClinoReactor using FIJI - Application Note | `Celvivo/111_Planimetry_ClinoReactor_FIJI_2026-07-17.md` |
-| `111_appnote` | CelVivo | Spheroid quantification | Planimetry measurements of spheroids in a ClinoReactor using FIJI — Application Note | `Celvivo/111_Planimetry_ClinoReactor_FIJI_2026-07-17.md` |
+| `Raji_2026_hMOs` | 3Brain | 多巴胺 / 中脑类器官 | Engineering functional ventral midbrain dopaminergic neurons in human organoids (hMOs + 3Brain HD-MEA) | `3Brain/Raji_2026_hMOs_dopaminergic_3Brain_MEA_2026-07-27.md` |
-| `Raji_2026_hMOs` | 3Brain | Dopaminergic / midbrain organoid | Engineering functional ventral midbrain dopaminergic neurons in human organoids (hMOs + 3Brain HD-MEA) | `3Brain/Raji_2026_hMOs_dopaminergic_3Brain_MEA_2026-07-27.md` |
+| `Tasevska_2025_HCTZ` | Cellink | 缓释药片 | 3D printed extended-release hydrochlorothiazide tablets (SSE 工艺, BIO X 适用) | `Cellink/Tasevska_2025_HCTZ_3D_printed_extended_release_2026-07-27.md` |
 | `Tasevska_2025_HCTZ` | Cellink | Extended-release tablet | 3D printed extended-release hydrochlorothiazide tablets (SSE process, BIO X compatible) | `Cellink/Tasevska_2025_HCTZ_3D_printed_extended_release_2026-07-27.md` |
 ### 2026-07-05
-
+| DOI | Vendor | 类器官 | 标题 | 路径 |
-| DOI | Vendor | Application | Title (short) | Vault path |
+|---|---|---|---|---|
 | --- | --- | --- | --- | --- |
 | `10.1002_btpr.2528` | CelVivo | Spheroid dissociation | Novel fluid shear-based dissociation device for improved single cell dissociation of spheroids | `Celvivo/10.1002_btpr.2528.md` |
-### 2026-06-25 (2 papers)
+### 2026-06-25 (2 篇)
-
+| DOI | Vendor | 类器官 | 标题 | 路径 |
-| DOI | Vendor | Application | Title (short) | Vault path |
+|---|---|---|---|---|
-| --- | --- | --- | --- | --- |
+| `10.1016_j.stemcr.2025.102646` (v1) | CelVivo | 通用 | High-throughput human microfluidic organoid-on-a-chip platform | `Celvivo/10.1016_j.stemcr.2025.102646.md` |
-| `10.1016_j.stemcr.2025.102646` (v1) | CelVivo | Generic | High-throughput human microfluidic organoid-on-a-chip platform | `Celvivo/10.1016_j.stemcr.2025.102646.md` |
+| `10.1016_j.stemcr.2025.102646_v2` | CelVivo | 通用 | 同上 v2 (重写) | `Celvivo/10.1016_j.stemcr.2025.102646_v2.md` |
-| `10.1016_j.stemcr.2025.102646_v2` | CelVivo | Generic | Same as v1, rewritten | `Celvivo/10.1016_j.stemcr.2025.102646_v2.md` |
+
-
+### 2026-06-24 (2 篇)
-### 2026-06-24 (2 papers)
+| DOI | Vendor | 类器官 | 标题 | 路径 |
-
+|---|---|---|---|---|
-| DOI | Vendor | Application | Title (short) | Vault path |
+| `10.1021_acsomega.5c02682` | 3Brain | 皮肤 | Developing tumor microenvironment in rotating human melanoma cell culture | `3Brain/10.1021_acsomega.5c02682.md` |
-| --- | --- | --- | --- | --- |
+| `10.1016_j.xpro.2025.103923` | CelVivo | 肺 | Protocol for the Establishment and Characterization of Lung Tumoroids | `Celvivo/10.1016_j.xpro.2025.103923.md` |
-| `10.1021_acsomega.5c02682` | 3Brain | Skin | Developing tumor microenvironment in rotating human melanoma cell culture | `3Brain/10.1021_acsomega.5c02682.md` |
+
-| `10.1016_j.xpro.2025.103923` | CelVivo | Lung | Protocol for the Establishment and Characterization of Lung Tumoroids | `Celvivo/10.1016_j.xpro.2025.103923.md` |
+### 2026-06-23 (2 篇)
-
+| DOI | Vendor | 类器官 | 标题 | 路径 |
-### 2026-06-23 (2 papers)
+|---|---|---|---|---|
-
+| `10.1002_jbm4.10792` | CelVivo | 通用 | High-throughput microfluidic organoid-on-a-chip (v2-munir2023) | `Celvivo/10.1002_jbm4.10792-v2-munir2023.md` |
-| DOI | Vendor | Application | Title (short) | Vault path |
+| `10.3390_cells11203216` | CelVivo | 肝 NAFLD | Mapping Proteome and Lipidome Changes in Early-Onset NAFLD | `Celvivo/10.3390_cells11203216.md` |
-| --- | --- | --- | --- | --- |
+
-| `10.1002_jbm4.10792` | CelVivo | Generic | High-throughput microfluidic organoid-on-a-chip (v2-munir2023) | `Celvivo/10.1002_jbm4.10792-v2-munir2023.md` |
+## 按 Vendor 统计 (mtime 2026-06-16 → 2026-07-28)
-| `10.3390_cells11203216` | CelVivo | Liver NAFLD | Mapping Proteome and Lipidome Changes in Early-Onset NAFLD | `Celvivo/10.3390_cells11203216.md` |
+
-
+| Vendor | 30 天精读数 | 最近一篇 |
-## Vendor statistics (mtime 2026-06-16 → 2026-08-08)
+|---|---|---|
-
+| **CelVivo** | 5 篇 | 2026-07-05 |
-| Vendor | 30-day deep-read count | Most recent | New this run (2026-08-08) |
+| **3Brain** | 1 篇 | 2026-06-24 |
-| --- | ---: | --- | --- |
+| **Cellink** | 1 篇 | 2026-07-27 |
-| **CelVivo** | 5 | 2026-07-05 | — |
+| **Ronawk Bio-Block** (KB 0 命中) | 1 篇 | 2026-07-28 |
-| **3Brain** | 1 (+ Liu 2026 + Sharma 2026 as adjacent) | 2026-06-24 (canonical) / 2026-08-08 (Liu / Sharma as HD-MEA-adjacent) | Liu 2026 (HD-MEA rating 5), Sharma 2026 (HD-MEA rating 4) |
+
-| **Cellink** | 1 | 2026-07-27 | — |
+## 4 周 MSC 长期培养关键词命中 (累计)
-| **CelVivo + 3Brain cross** | 1 | 2026-07-27 | Miao 2025 v2 (CelVivo ClinoStar rating 5, HD-MEA rating 4) |
+
-| **Cellink + 3Brain cross** | 0 | — | Liu 2026 (3D bioprinting microlattice rating 5) |
+- `Bio-Block Ronawk 3D culture mesenchymal` (2026-07-28 入库, **未 KB 验证**; 4 周时窗 vs 2D/球体/Matrigel 平台对比)
-| **Across all 4 vendors** (Microbioreactor review) | 1 | 2026-08-08 | Rosero 2026 Front Bioeng Biotechnol (CAR-T / mAb / iPSC / organoid — 4 applications) |
+- `Hodge Mellott Bio-Block 3D culture` (2026-07-28 入库, **未 KB 验证**; 同上 Ronawk 团队 USC Kansas)
-| **Brain organoid + THSDC** (NAMs adjacent) | 1 | 2026-08-08 | Fernandez Vallone 2026 Cells (hiPSC brain organoid THSDC platform, v2 5 张真图 + 双 H1; Wiki.js Id 1698) |
+
-| **Brain organoid + PD model** | 1 | 2026-08-06 | Parfitt 2024 Nat Commun (DJ1 LOF midbrain organoid PD model, untracked) |
+## ClinoReactor 关键词命中 (累计)
-| **Ronawk Bio-Block** (KB 0 hit) | 1 | 2026-07-28 | — |
+
-
+- `Planimetry measurements of spheroids in a ClinoReactor using FIJI` (2026-04-01 入库, **未精读**)
-## 4-week MSC long-term-culture keyword hits (cumulative)
+
-
+## 跟 OpenWiki 其他源的关系
- `Bio-Block Ronawk 3D culture mesenchymal` (2026-07-28 added, **not KB-validated**; 4-week window vs 2D/spheroid/Matrigel platform comparison)
+
- `Hodge Mellott Bio-Block 3D culture` (2026-07-28 added, **not KB-validated**; same Ronawk team USC Kansas)
+| 源 | 看什么 |
-
+|---|---|
-## ClinoReactor keyword hits (cumulative)
+| **本文件** (literature.md) | 精读笔记 (本文件) |
-
+| `sources/hackernews.md` | 外部公开讨论 |
- `Planimetry measurements of spheroids in a ClinoReactor using FIJI` (2026-04-01 added, **not yet deep-read**)
+| `sources/git-repo.md` | vault 整体结构 |
-
+| `commitments.md` | Robin 任务承诺 |
-## Flywheel-sync pipeline (today, 2026-08-08)
+| `themes.md` | 跨源主题综合 |
-
+
-The `~/.hermes/data_sources/literature_flywheel.jsonl` records each paper's 8-step pipeline status (`type_judgment` → `pdf_full_text` → `image_extract` → `ollama_audit` → `seafile_upload` → `report_written` → `wiki_published` → `nocodb_patched` → `obsidian_pushed` → `openwiki_pushed` → `flywheel_index`). Today's `flywheel_index` completions:
+## 触发查询示例 (MiniMax code 用)
-
+
-| Paper | NocoDB destination | Wiki.js URL | Wiki Id |
+- "Robin 最近精读了哪些 CelVivo 文献" → 读本文件 CelVivo 段
-| --- | --- | --- | ---: |
+- "ClinoReactor 相关最新研究" → 读本文件 ClinoReactor 段 + ClinoReactor 关键词命中
-| Liu 2026 Nat Biomed Eng | **new table `Robin_Picked_Papers`** (created 2026-08-08, table_id `mbjo0wb56qv1qly`, row_id 1) | https://wiki.biokingdom.top/zh/literature/liu-2026-nbme-shape-conformal-organoid | 1692 |
+- "近一周有什么新文献" → 读本文件 "最近 7 天" 段
-| Miao 2025 Cell v2 | `Organoid_Literature` table (row 93) | https://wiki.biokingdom.top/zh/literature/miao-2025-cell-organoid-vascularization-v2 | 1681 |
+
-| Sharma 2026 Cell Stem Cell | `Organoid_Literature` table (row 700) | http://10.10.10.254:3000/zh/literature/sharma-2026-cell-stem-cell-vascularized-retinal-organoid-rgc | 1678 |
+## 维护方式
-
+
-The `Robin_Picked_Papers` table is **new as of today** — created per Robin's 2026-08-08 instruction to capture papers Robin hand-picks / provides outside the regular PubMed triage. Liu 2026 is the first entry. This is **separate** from the existing `Organoid_Literature` table (which Miao 2025 v2 + Sharma 2026 landed in).
+- **手动触发**: 通知 Robin "更新 literature 索引"
-
+- **自动**: OpenWiki cron 每天 02:00 跑 git-repo connector, 写本文件
-## Cross-reference with other OpenWiki sources
+- **路径**: `~/.openwiki/wiki/sources/literature.md` (同步推 Gitea)
-
+### 2026-07-28
-| Source | Look here for |
+| DOI | Vendor | 类器官 | 标题 | 路径 |
-| --- | --- |
+|---|---|---|---|---|
-| **This page** (`/sources/literature.md`) | Deep-read notes index + flywheel-sync pipeline status |
+| `10.1080_17460751.2025.2572177` | Ronawk Bio-Block (KB 0 命中) | MSC / 脂肪源 | Comparison of 3D culture systems on MSC longevity (Hodge 2025) | `RegenMed/10.1080_17460751.2025.2572177.md` |
-| [`/sources/hackernews.md`](/sources/hackernews.md) | External public discussion |
+| `10.1186_s13287-018-1085-9` | KB: CelVivo+Cellink 命中 | MSC / 3D 漂浮 | Type I collagen deposition ameliorates YAP/TAZ (Komatsu 2018) | `Cellink/10.1186_s13287-018-1085-9.md` |
-| [`/sources/git-repo.md`](/sources/git-repo.md) | Vault overall structure |
+| `10.3389_fvets.2025.1500267` | KB: 0 命中 | MSC 犬源 | Enhanced immunomodulation of canine MSC 3D (Lee 2025) | `Other/10.3389_fvets.2025.1500267.md` |
-| [`/commitments.md`](/commitments.md) | Robin's task commitments |
+| `10.1186_s13287-020-1566-5` | KB: CelVivo+Cellink 命中 | MSC / PEMF / 软骨 | PEMF potentiate MSC paracrine cartilage (Parate 2020) | `Other/10.1186_s13287-020-1566-5.md` |
-| [`/themes.md`](/themes.md) | Cross-source synthesis |
+
-| [`/themes/01-organoid-equipment.md`](/themes/01-organoid-equipment.md) | CelVivo + 3Brain vendor synthesis (with HD-MEA + ClinoStar evidence anchors for Liu 2026 / Miao 2025 v2 / Sharma 2026) |
+### 2026-08-04 (ITX 端 hermes test)
-| [`/themes/02-bioprinting.md`](/themes/02-bioprinting.md) | Cellink + 3D bioprinting synthesis (with Liu 2026 microlattice evidence anchor) |
+| DOI | Vendor | 类器官 | 标题 | 路径 |
-
+|---|---|---|---|---|
-## Trigger queries (for MiniMax code)
+| `10.1038_s41586-026-assembloids-periportal` | Nature 650, 438-449 | Liver / Assembloid | Human assembloids recapitulate periportal liver (Yuan 2026) | `Organoid/10.1038_s41586-026-assembloids-periportal.md` |
 - "What CelVivo papers has Robin deep-read recently?" → read this page's CelVivo rows + `/themes/01-organoid-equipment.md` CelVivo section
 - "Latest ClinoReactor research" → read this page's ClinoReactor keyword hits + Miao 2025 v2 (vascularization cross-reference)
 - "What new papers in the past week?" → read this page's "Last 30 days" section, top 3 rows
 - "Liu 2026 shape-conformal neural organoid HD-MEA — what is it?" → [`/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md`](/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md)
 - "Fernandez Vallone 2026 hiPSC brain organoid THSDC — what is it?" → deep-read at `obsidian-vault/04-Literature/Deep-Reads/Cells/fernandez-vallone-2026-thsdc-brain-organoids.md` (Wiki.js Id 1698, NocoDB row 3263, v2 with 5 张真图 + 双 H1)
 - "Parfitt 2024 DJ1 LOF midbrain organoid PD model — what is it?" → deep-read at `04-Literature/Deep-Reads/Brain/2026-08-06_Parfitt_GM_et_al_NatCommun_2024_DJ1_LOF_midbrain_organoid_PD.md` (Nat Commun 15:1071, PMID 38200091)
 ## 8-07 vault mtime additions (working-tree deep-reads — not yet on `main`)
 > Observed in the 2026-08-08 git-repo connector pull as **untracked files in the working tree**. These are working-tree deep-reads that the next LDR commits will fold onto `main`.
 | Path | Status | Note |
 | --- | --- | --- |
 | `Liu2026_NBME_shape_conformal_organoid.md` | untracked @ `/home/ldw/workspace/` | canonical 2026-08-08 paper; v2-v11 已经 commit `1614ccf9` to `main` |
 | `Miao2025_Cell_v2.md` | untracked @ `/home/ldw/workspace/` | canonical 2026-08-08 paper; v2 已 commit `1c05eee7` to `main` |
 | `Miao2025_Cell_vascularized_organoid.md` | untracked @ `/home/ldw/workspace/` | 出处未明 working copy |
 | `Microbioreactor_2026_Rosero_FrontBioeng.md` | untracked @ `/home/ldw/workspace/` | 2026-08-08 论文 working copy; v2 with SeaFile links 已 commit `65fef021` to `main` |
 | `04-Literature/Deep-Reads/Brain/2026-08-06_Parfitt_GM_et_al_NatCommun_2024_DJ1_LOF_midbrain_organoid_PD.md` | untracked (2026-08-06) | DJ1 LOF midbrain organoid PD model (Parfitt 2024 Nat Commun) |
 | `obsidian-vault/04-Literature/Deep-Reads/Cells/fernandez-vallone-2026-thsdc-brain-organoids.md` | untracked (2026-08-08) | Fernandez Vallone 2026 Cells hiPSC 脑类器官 THSDC (commits `6c16dc05` + `d7df3830`) |
 | `retinal_organoid_deep_read_2026-08-07.md` | untracked @ `/home/ldw/workspace/` | Sharma 2026 working copy |
 | `rustdesk-selfhosted-2026-08-05.md` | untracked @ `/home/ldw/workspace/obsidian-vault/` | 独立的 RustDesk 自建部署笔记 (related to `/sources/rustdesk-sop.md`) |
 | `dify精读进度-20260805.md` | untracked @ `/home/ldw/workspace/` | Dify 文档精读进度追踪 |
 | `literature_deepread_v6.py` + `__pycache__/` | untracked @ `/home/ldw/workspace/` | LDR pipeline v6 脚本 (脚本源) |
 | `文悦精读流程线.yml` v1-v5-clean | untracked @ `/home/ldw/workspace/` | Dify 精读流程线 workflow YAML (5 版迭代) |
 ## 8-07 _known_associations.md 接续
 > 2026-08-07 added Obsidian vault `02-Clients/Agents/_known_associations.md` 是 4 个经销商管理 Hook 升级 (commit `4b237a82`) 的输出。这页 index 是新引入的 cross-product mapping — connector 证据已在 [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md) § "8-07 新增：_known_associations.md 索引" 索引。
 ## Maintenance
 - **Manual trigger:** notify Robin "update literature index"
 - **Automatic:** OpenWiki cron 02:00 daily runs the git-repo connector + observes the flywheel-sync jsonl; the `## Last 30 days of deep reads` section is updated by mtime census, and the `## Flywheel-sync pipeline` section is updated by inspecting the `flywheel_completed_at` field.
 - **Path:** `~/.openwiki/wiki/sources/literature.md` (synced to Gitea)
 ### 2026-08-11 - PMID 42041571
 - **Title**: Multiscale Comparative Analyses of OVB-Organoids and Cerebral Organoids
 - **Authors**: Yang J, Zhang X, Li S, Gao Z
 - **Journal**: Cells 2026, 15(8), 703 (MDPI, IF ~5.1, CC-BY OA)
 - **DOI**: 10.3390/cells15080703
 - **Wiki.js**: [ID 1708](http://10.10.10.254:3000/zh/organoid/ovb-cerebral-organoid-multiscale-2026)
 - **NocoDB Id**: 1103
 - **PDF**: [cells_15_00703.pdf](https://fb.biokingdom.top/f/582d1f055f6e4365a924/?raw=1) + 10 张真实配图(xref extract)
 - **Key finding**: Cells 2026 重磅 - OVB-organoids vs Cerebral 多尺度对比(中国军事医学科学院); Day 30 FOXG1+53.86% + VSX2+4.18%; TEM 突触+髓鞘; 1625 上调 + 2924 下调 DEGs; CHRNB2 6.5 倍差异; KEGG 富集到神经突触功能 vs 免疫炎症代谢
 - **Business relevance**: OVB-organoids + 3Brain MEA = 眼-脑协同发育研究完整解决方案
 - **Tags**: OVB-organoids, cerebral-organoids, brain-development, retinal-organoid, FOXG1, VSX2
 ### 2026-08-11 - PMID 41909700
 - **Title**: Organoid-microglia system for modeling the immune microenvironment of the brain and retina
 - **Authors**: Yu J, Tang B, Gu Z, Wang G, Liu A
 - **Journal**: Frontiers in Immunology 2026, 17:1747589
 - **DOI**: 10.3389/fimmu.2026.1747589
 - **Wiki.js**: [ID 1709](http://10.10.10.254:3000/zh/organoid/yu-2026-organoid-microglia-front-immunol)
 - **NocoDB Id**: 715
 - **PDF**: [yu_2026_organoid_microglia.pdf](https://fb.biokingdom.top/f/4537d08bf4d14c6db0bc/?dl=1) + 4 张真图
 - **Key finding**: 类器官-小胶质细胞共培养 3 大策略 + 6 大应用 (AD/ASD/视网膜/药筛/CRISPR/OoC); 神经-免疫体外模型空白填补
 - **Business relevance**: 3Brain MEA + CelVivo ClinoStar + Femtobiomed CellShot + Cellink BIO X 4 大产品线全交叉
 - **Tags**: 类器官, 小胶质细胞, 神经免疫, 脑-视网膜, 共培养
 ### 2026-08-11 - PMID 41686639
 - **Title**: High-throughput engineered tumor organoids reveal ROCK signaling as an immunotherapeutic target in triple-negative breast cancer
 - **Authors**: Zhou X, Zhu Y, Nicolas G, Wang Z, Lobie P, Ma S
 - **Journal**: Cell Reports 2026, 45:116987
 - **DOI**: 10.1016/j.celrep.2026.116987
 - **Wiki.js**: [ID 1710](http://10.10.10.254:3000/zh/organoid/zhou-2026-deo-rock-tnbc-cell-reports)
 - **NocoDB Id**: 3296
 - **PDF**: [zhou_2026_cell_reports_rock_tnbc.pdf](https://fb.biokingdom.top/f/bbe6f494811047c2bba0/?dl=1) + 6 张真图
 - **Key finding**: DEO 平台保留 TNBC 患者内源 TIL;ROCK 通路激动剂戊酸(PA)维持 TIL + 协同 anti-PD-1 解除 BLIS 亚型免疫抑制(联合治疗肿瘤抑制率 ~70%)
 - **Business relevance**: 4 大产品线全交叉 (CelVivo ClinoStar 培养/3Brain MEA 评估/Femtobiomed CellShot 基因编辑/Cellink BIO X 制造)
 - **Tags**: 肿瘤类器官, 三阴乳腺癌, ROCK信号, TIL, anti-PD-1, 戊酸, 马少华, BLIS亚型
 ### 2026-08-11 - PMID 41536916
 - **Title**: Artificial Intelligence Virtual Organoids (AIVOs)
 - **Authors**: Bai L, Su J
 - **Journal**: Bioactive Materials 2026 (IF 18.2)
 - **DOI**: 10.1016/j.bioactmat.2025.12.030
 - **Type**: Review
 - **Wiki.js**: [ID 1711](http://10.10.10.254:3000/zh/organoid/bai-2026-aivos-bioactmat)
 - **NocoDB Id**: 502
 - **PDF**: [bai_2026_bioactmat_aivos.pdf](https://fb.biokingdom.top/f/59c6a647037346a28197/?dl=1) + 6 张真图
 - **Key finding**: AI Virtual Organoids (AIVOs) = 物理类器官 + AI 数字孪生; 数据-模型-交互三层架构; 6 大临床应用方向
 - **Business relevance**: 4 大产品线 (CelVivo ClinoStar / 3Brain MEA / Femtobiomed CellShot / Cellink BIO X) 全部可对接 AIVOs 平台 = 完整 湿+干 实验方案
 - **Tags**: 综述, 类器官, 人工智能, 虚拟器官, 数字孪生, 多组学, Bioactive-Materials-2026
 | 10.1038/s41598-026-42990-2 | Sci Rep 2026 | Liver | Liang 2026 小鼠肝类器官成熟+纤维化建模平台 | obsidian-vault/04-Literature/Deep-Reads/Liver/2026-08-12_Liang_2026_SciRep_liver_organoid_fibrosis_platform.md |
 ## 2026-08-24 - Ajongbolo & Langhans 2025 Cells (PMID 40498018)
 - **DOI**: 10.3390/cells14110842 | **JIF**: 7.0 (Cells MDPI)
 - **Wiki.js**: https://wiki.biokingdom.top/literature/ajongbolo-2025-cells-brain-organoids-review (ID 1743)
 - **主题**: 脑类器官 + assembloid + 类器官芯片 + tumoroid 四大范式综述;神经发育/神经退行/脑肿瘤建模与高通量药物筛选
 - **关键发现**: 综述把脑类器官从分散成果整合成标准化决策树;神经发育建模最成熟(复现率 70%+),脑肿瘤个性化最高
 - **配图**: 2 张 (Fig 1 分类树 + Fig 2 表征方法分类) — Wiki.js /u 公网, ADOPT 2/2
 - **PDF**: NAS SMB fallback (8-18 坑 12 命中第 2 次, Cloudreve share 返 200 但公网 404)
 ## 8-24 精读报告永久格式规则 (Robin 拍板)
 1. **不写本地副本路径** — 报告末尾 PDF 行后不再加 NAS SMB 路径
 2. **转发语加 "转发语:" 前缀** — 末尾 `> **转发语:**` 起头,不裸 `>`
 3. 这 2 条永久生效, 未来精读报告 + patch 必守
 ## 2026-08-24 - Kim et al. 2025 Nat Commun (PMID 40016200)
 - **DOI**: 10.1038/s41467-024-55752-3 | **JIF**: 16.6 (Nat Commun)
 - **Wiki.js**: https://wiki.biokingdom.top/literature/kim-2025-natcommun-liquid-metal-3d-mea (ID 1744)
 - **主题**: 液态金属(EGaIn)3D pillar MEA + 磁可重塑 + 皮层类器官内部 SU 电生理记录 + 6 月成熟度量化
 - **关键发现**: 首次实现类器官**内部**单单元电生理记录 + 噪声 13 μV + 6 月成熟(spike rate↑, burst duration↑, p<0.05);磁场驱动 pillar 重塑 20 循环稳定
 - **配图**: 6 张 (Fig 1-6, ADOPT 6/6) — Wiki.js /u 公网
 - **PDF**: NAS SMB fallback (8-18 坑 12 第 3 次命中,Nature 系 frp/share-handler 系统性 bug)
 - **PDF 直链可用**: https://www.nature.com/articles/s41467-024-55752-3.pdf (Nature 子刊 PDF 公开访问)
 ## 8-24 精读配图永久规则 (Robin 拍板)
 1. **多 panel 复合图必须整页渲染** — caption_y 裁剪到 caption 上方, 覆盖 panel 字母
 2. **嵌入大图 xref 仅用于单 panel 纯图像图** — 嵌入图本身不含文字标注
 3. **Springer Nature 系双栏全宽 Figure** — caption 在图下方, 整页渲染到 caption_y - 15
 4. **视觉审核 panel 数 ≥ 原文 caption 声明** — 是判 ADOPT 的硬阈值
 5. 这 4 条永久生效, 未来精读 + patch 必守
 ## 8-24 v2 二次反馈: Springer Nature PDF 嵌入图只含部分 panel
 - 根因: PDF 嵌入图 xref 只含 raster 部分, 部分 panel 是矢量绘制 (PDF vector, 无 xref)
 - 修法: 每个 Figure 走"完整 page 渲染" — 从 page 顶部 (y=33 article header 后) 到 caption_y - 15
 - 实战: Kim 2025 Fig 5 嵌入图 xref 212 只含 f-j 网络图, 完整 Fig 5 还有 a-e SU trace + 柱状图 (5 个矢量绘制 panel)。Fig 5 v4: 228/50 ADOPT, 10/10 panels 全在
 - 这条永久生效, 未来精读 + patch 必守
 ## 2026-08-24 - Tian et al. 2025 Nat Commun (PMID 40593704)
 - **DOI**: 10.1038/s41467-025-60934-8 | **JIF**: 16.6 (Nat Commun)
 - **Wiki.js**: https://wiki.biokingdom.top/literature/tian-2025-natcommun-epicardium-mtor (ID 1745)
 - **主题**: mTORC1/2 双抑制 (Torin1) 驱动 hiPSC 心外膜成熟, YBX3/MAFF TF 轴 + 3D 类器官 + 心肌旁分泌共培养
 - **关键发现**: 379 DEGs; 心外膜转录组从胎儿表型推到成体; mTORC2 是关键节点; 心外膜旁分泌 IGF2/FN1 推动心肌 TNNI3 成熟
 - **配图**: 7 张 (Fig 1-7, 4/7 ADOPT Fig 4-7, Fig 1-3 待限流补审) — v5 智能渲染 (含跨页拼接)
 - **PDF**: NAS SMB fallback (8-18 坑 12 第 4 次命中)
 ## 2026-08-24 - Aiello & Bagni biorxiv preprint (CelVivo KB 来源)
 - **Title**: Design and validation of a low-shear Rotating Chamber system for brain organoid culture
 - **Source**: RAGFlow CelVivo KB (1555e5b2... 170 docs), Brain_Organoid_Fluid_biorxiv.pdf (14MB, 49 chunks)
 - **Wiki.js**: https://wiki.biokingdom.top/literature/aiello-bagni-2025-biorxiv-rotating-chamber-brain-organoid (ID 1746)
 - **主题**: CelVivo ClinoStar 旋转腔 COMSOL CFD 量化 (<20 mPa 剪切力) + 跨细胞系/批次形态变异系数 <15% + 完整皮层细胞类型与代谢成熟
 - **配图**: 5 张 (Fig 1-5, MiniMax 限流未审) — v3 拼接 (figure 在 page 40-44, caption 在 page 32-35, 跨页布局)
 - **PDF**: NAS SMB fallback
 ## 2026-08-24 - CelVivo App Note shear stress (CelVivo KB 来源)
 - **Title**: Influence of shear stress on long-term 3D construct performance: Comparison of orbital shaker and ClinoStar system
 - **Source**: RAGFlow CelVivo KB (1555e5b2... 170 docs), Shear_Stress_OS_CelVivo_appnote.pdf (1.4MB, 11 chunks)
 - **Wiki.js**: https://wiki.biokingdom.top/literature/celvivo-appnote-shear-stress-2026 (ID 1747)
 - **主题**: CelVivo 官方 App Note — ClinoStar vs Orbital Shaker head-to-head 对比 HepG2/C3A + Caco-2 + 脑 organoid 三模型, 证明低剪切力优势跨细胞模型可复现
 - **配图**: 5 张 (Fig 1-5, MiniMax 限流未审) — v4 智能拼接 (xref bbox + caption 段)
 - **PDF**: NAS SMB fallback
 ## 2026-08-25
 ## Tevonian 2026 Nat Commun 血管化肝 MPS (PMID 41634021)
 - **DOI**: 10.1038/s41467-025-68031-6
 - **Path**: literature/tevonian-2026-nat-commun-vascularized-liver-mps
 - **Wiki ID**: 1749
 - **关键发现**: PDMS+fibrin+原代肝+HUVEC 血管化肝 MPS, 14天 IR 建模, 单核细胞浸润增强
 - **Robin 业务对接**: MASLD/NASH 体外建模 + 个性化药筛 + 血管化类器官平台
 ## Yang 2026 Stem Cell Res Ther cardiac organoid review (PMID 41963991)
 - **DOI**: 10.1186/s13287-026-04996-5
 - **Path**: literature/yang-2026-stem-cell-res-ther-cardiac-organoid-review
 - **Wiki ID**: 1750
 - **关键发现**: 复旦 + InnoStar 综述从化学定义 hiPSC 到自组织心脏类器官的完整路径, 涵盖 FGF/PI3K/Wnt/BMP/Activin/RA 五大信号通路 + 三种 3D 培养策略
 - **Robin 业务对接**: 心脏药物毒性测试 + hiPSC 衍生心脏类器官服务 + 心血管疾病建模
 ## Shen 2026 Chin Med J vascularized organoids review (PMID 42268296)
 - **DOI**: 10.1097/CM9.0000000000004136
 - **Path**: literature/shen-2026-cmj-vascularized-organoids
 - **Wiki ID**: 1751
 - **关键发现**: 华西医院综述血管化类器官 4 大策略(共培养 + 转录因子诱导 + 微流控 + 生物材料支架) + 12 维对比 + 三大未来方向
 - **Robin 业务对接**: 血管化类器官服务 + 多层血管网络平台 + 个性化精准医疗
 ## Zhai 2026 Sci Adv 3D skin pemphigus (PMID 41512055)
 - **DOI**: 10.1126/sciadv.adz5003
 - **Path**: literature/zhai-2026-sciadv-3d-skin-pemphigus
 - **Wiki ID**: 1752
 - **关键发现**: 3D 打印 + 自组织多层血管化皮肤模型, 建模天疱疮自身免疫 + EGFR 靶向治疗 + ML 辅助药筛
 - **Robin 业务对接**: 皮肤自身免疫病药筛 + 3D 打印客户 + 精准医疗应用
 ## 2026-08-31 (5-paper CelVivo-anchored single-shot LDR burst — NEW `CelVivo/` capital-V parallel subfolder)
 ## Stewart 2023 Front Microbiol BA.5/XBB neurotropic brain organoids (PMID 37984455)
 - **DOI**: 10.3389/fmicb.2023.1320856
 - **Path**: `obsidian-vault/04-Literature/Deep-Reads/CelVivo/stewart-2023-ba5-xbb-neurotropic-brain-organoids.md`
 - **QIMR Berghofer Medical Research Institute** + University of Queensland
 - **关键发现**: SARS-CoV-2 omicron BA.5 + XBB variants have **increased neurotropic potential over BA.1** in K18-hACE2 mice + human brain organoids (CelVivo ClinoStar); MA1 infection cell count higher in brain organoids
 - **Robin 业务对接**: 病毒神经嗜性 + 变异株 screening + 抗病毒药筛
 ## Aiello 2025 EMBO reports brain organoid reproducibility (PMID 40976390)
 - **DOI**: 10.1038/s44319-025-00619-x
 - **Path**: `obsidian-vault/04-Literature/Deep-Reads/CelVivo/aiello-2025-brain-organoid-reproducibility.md`
 - **洛桑大学** + 罗马 Tor Vergata 大学 + 西北大学 (南非) + **CelVivo ApS (丹麦) co-author**
 - **关键发现**: 受控流体动力学提高脑类器官可重复性 — **CV <15% morphological consistency** vs static culture CV >30% across multi-batch + multi-iPSC-line brain organoid cultures; cortical cell type recapitulation (SOX2/Nestin/PAX6 + DCX + TBR1/SATB2/MAP2 multi-marker IHC) + scRNA-seq OXPHOS metabolic profiling
 - **Robin 业务对接**: 脑类器官可重复性金标准 + 三甲医院 / 中国脑科学客户 + CDMO brain organoid manufacturing benchmark + multi-iPSC-line cross-validation reference
 ## Nguyen 2024 npj Viruses JEV G4 2022 Australia brain organoids (PMID 39384709)
 - **DOI**: 10.1038/s44298-024-00025-5
 - **Path**: `obsidian-vault/04-Literature/Deep-Reads/CelVivo/nguyen-2024-jev-g4-2022-australia-brain-organoids.md`
 - **QIMR Berghofer Medical Research Institute** + INRAE
 - **关键发现**: 2022 澳大利亚爆发的日本脑炎病毒基因 4 型分离株特征研究 — JEV G4 isolate characterization using human brain organoids (CelVivo ClinoStar) + mouse model
 - **Robin 业务对接**: 虫媒病毒 (JEV / Zika / dengue) 神经嗜性研究 + 疫苗开发 + 抗病毒药筛 + 东南亚 + 中国南方 + 西太平洋 客户对接
 ## Miao 2025 Cell vascularized lung/gut organoids v1 published version (PMID 40713703)
 - **DOI**: 10.1016/j.cell.2025.05.041
 - **Path**: `obsidian-vault/04-Literature/Deep-Reads/CelVivo/miao-2025-vascularized-lung-gut-organoids.md`
 - **关键发现**: 中胚层与内胚层共分化实现肺和肠道类器官的器官型血管化 — companion to the 2026-08-08 flywheel-sync Miao 2025 v2 deep-read; **Cell published version** extends the v2 deep-read with the canonical CelVivo ClinoReactor co-differentiation mesoderm+endoderm platform + scRNA-seq single-cell profiling of FOXF1 endothelial-mesenchymal transition
 - **Robin 业务对接**: lung organoid + gut organoid + 血管化 + 呼吸道病毒 / 肠道病毒感染模型 + 中国肺纤维化 / IBD pharma R&D positioning
 ## Yan 2024 Cell Reports TMEM106B SARS-CoV-2 ACE2-independent brain organoids (PMID 39576284)
 - **DOI**: 10.1016/j.celrep.2024.114921
 - **Path**: `obsidian-vault/04-Literature/Deep-Reads/CelVivo/yan-2024-tmem106b-sars-cov2-ace2-independent.md`
 - **QIMR Berghofer Medical Research Institute**
 - **关键发现**: TMEM106B 介导的 SARS-CoV-2 感染：体外强效 ACE2 非依赖感染但体内不成立 — CRISPR 筛选鉴定 TMEM106B/硫酸乙酰肝素/内吞介导 ACE2 非依赖进入 in human cortical brain organoids (CelVivo ClinoStar); MA1 神经毒力更强 in vitro; in vivo 不成立
 - **Robin 业务对接**: viral entry mechanism + 抗病毒药筛 + brain organoid platform validation
 ## https://fb.biokingdom.top/api/v4/file/content/m99qHL/0/pasca...
 - **Title**: Human assembloid model of the ascending neural sensory pathway
 - **Authors**: Ji-il Kim, Kent Imaizumi, Ovidiu Jurjut, Kevin W. Kelley, Dong Wang, Mayuri V. Thete, Zuzana Hudacova, Neal D. Amin, Rebecca J. Levy, Gregory Scherrer, Sergiu P. Pasca
 - **Venue**: Nature (5 June 2025)
 - **DOI**: 10.1038/s41586-025-08808-3
 - **PMID**: 40205039 | **PMC**: PMC12137141
 - **Wiki.js**: https://wiki.biokingdom.top/literature/pasca-2025-nature-hasa-assembloid (ID 1758)
 - **NocoDB Brain 表**: Id=104
 - **PDF**: https://fb.biokingdom.top/api/v4/file/content/m99qHL/0/pasca-2025-assembloid-20260827.pdf
 - **Citations**: 99 (Nature 主刊 4 个月)
 - **Business match**: CelVivo ClinoStar ⭐⭐⭐⭐⭐ + 3Brain BioCAM X ⭐⭐⭐⭐⭐ + Mimetas OrganoPlate ⭐⭐⭐⭐ + Cellink BIO X ⭐⭐⭐⭐ + Femtobiomed CellShot ⭐⭐⭐
 - **Method**: First 4-part assembloid (hSeO/hdSpO/hDiO/hCO) from hiPS cells, scRNA-seq (54K cells), rabies tracing, calcium imaging, MEA extracellular recording. SCN9A/NaV1.7 KO reproduces CIP (Congenital Insensitivity to Pain).
 - **Date added**: 2026-08-27
 ## iScience 2026 - Microgravity Reproductive Review
 - **Title**: A systematic review of microgravity on reproductive systems: Implications for space biology and human health
 - **Authors**: C.-F.L., C.-Y.C., P.-T.L., Y.-C.H. (corresponding)
 - **Venue**: iScience (13 Jan 2026)
 - **DOI**: 10.1016/j.isci.2026.114663
 - **PMID**: 41675042 | **PMC**: PMC12886544
 - **Wiki.js**: https://wiki.biokingdom.top/literature/microgravity-reproductive-review-2026 (ID 1759)
 - **NocoDB Brain 表**: Id=105
 - **PDF Status**: 5 路径 + S2 + Europe PMC 镜像全失败 (Robin 8-26 撞坑诚实停手);RAGFlow 解析文本 82546B 可下
 - **Method**: First cross-paradigm review (spaceflight + SMG + animal + human). 7 mechanisms (oxidative stress / DNA damage / cell signaling / cytoskeleton / mitochondria / EV / epigenetics). Countermeasures: AG / antioxidants / cryopreservation / RNAi.
 - **Date added**: 2026-08-27
 - **Stewart 2023 Front Microbiol 14:1320856** — SARS-CoV-2 omicron BA.5/XBB 较 BA.1 神经趋向性增强（K18-hACE2 小鼠 + CelVivo ClinoStar 培养的人源皮层脑类器官）。BA.5 感染类器官滴度高 1-2 log、RNA 高 25 倍，神经元为主要靶细胞，脑内细胞因子风暴主导。DOI: 10.3389/fmicb.2023.1320856 | Wiki: https://wiki.biokingdom.top/literature/stewart-2023-sarscov2-ba5-xbb-neurotropic-brain-organoids
 - **Aiello 2025 EMBO reports 26:6209-6239** — 通过受控流体动力学提高脑类器官可重复性：CelVivo ClinoReactor 垂直旋转培养降低流体剪切力(fFSS)，90天形态+10参数PCA显示跨批次/跨细胞系变异显著降低，17,738单细胞重现完整皮层细胞类型，OXPHOS代谢接近胎儿脑。CelVivo员工为共同作者。DOI: 10.1038/s44319-025-00619-x | Wiki: https://wiki.biokingdom.top/literature/aiello-2025-brain-organoid-reproducibility-rotating-chamber
 - **Nguyen 2024 npj Viruses Article 25** — 2022 澳大利亚 JEV 基因 4 型爆发株 JEVNSW/22 特征研究：三小鼠模型 (C57BL/6J/Irf7-/-/Ifnar-/-) 毒力低于 G2/G3 且对 I 型 IFN 敏感；人源皮层脑类器官 (CelVivo Clinostar 培养) 所有 JEV/MVEV 均致细胞病变感染；IMOJEV 疫苗可交叉中和。DOI: 10.1038/s44298-024-00025-5 | Wiki: https://wiki.biokingdom.top/literature/nguyen-2024-jev-genotype4-2022-australia-brain-organoids
 - **Miao 2025 Cell 188:1-19** — 中胚层-内胚层共分化 + CelVivo ClinoReactor 无 ECM 大规模培养 (约2000类器官/反应器) 实现肺/肠类器官器官型血管化：单细胞证实 aCap/gCap 毛细血管内皮 + 器官型间充质，体内移植重建人源血管网络，FOXF1/ACD 疾病模型。DOI: 10.1016/j.cell.2025.05.041 | Wiki: https://wiki.biokingdom.top/literature/miao-2025-vascularized-lung-gut-organoids-cell
 - **Yan 2024 Cell Reports 43:114921** — TMEM106B 介导 SARS-CoV-2MA1 (S-E484D) ACE2 非依赖进入：CRISPR 筛选锁定 TMEM106B/硫酸乙酰肝素/内吞；人源皮层脑类器官 (CelVivo ClinoStar 培养) 中神经毒力增强，但小鼠体内 ACE2 仍必需 (Ace2-/- 肺无法感染)。DOI: 10.1016/j.celrep.2024.114921 | Wiki: https://wiki.biokingdom.top/literature/yan-2024-tmem106b-sars-cov2-ace2-independent-brain-organoids
 - **Wang 2026 Cell Proliferation** - Liver Organoids: From Disease Modelling to Regenerative Medicine
  - DOI: 10.1111/cpr.70268 | PMID: 42599088 | PMCID: PMC13475025
  - Wiki.js: https://wiki.biokingdom.top/literature/liver-organoids-wang-2026-cell-proliferation-review (Page 1795)
  - PDF: https://fb.biokingdom.top/api/v4/file/content/j9l9UJ/0/Liver_Organoids_Wang_2026_CellProliferation_PMID42599088.pdf
  - 3 大爆点: 内皮共培养覆盖率 > 85% / Prime editing 无脱靶 / UTOpiA 生物人工肝
  - 6 大类肝病建模: MASLD / 纤维化 / DILI / 肝癌 PDO / 遗传 / 病毒
  - 5 大临床转化挑战: 功能成熟度 / 血管网络 / 标准化 / 质控 / 生物材料
  - 精读日期: 2026-09-17
  - 完成 5 sink: NocoDB comm Id=251 / Obsidian vault / flywheel JSONL / index.json / 4 张 Fig assets ID 3714-3717
 ## Scordamaglia 2025 J Transl Med - TNBC IL-1β / IGF1 / Celvivo ClinoReactor
 - **Date**: 2026-09-28
 - **PMID**: 40528207
 - **DOI**: 10.1186/s12967-025-06730-w
 - **Journal**: Journal of Translational Medicine (IF 7.5)
 - **Wiki.js Page**: https://wiki.biokingdom.top/literature/scordamaglia-2025-j-transl-med-il1b-tnbc-cafs-clinoreactor (ID 1810)
 - **PDF**: https://fb.biokingdom.top/api/v4/file/content/6JKriY/0/scordamaglia2025_TNBC_IGF1_IL1B.pdf (6.66 MB / 19 pages / Cloudreve sign URL 10 年)
 - **核心机制**: IGF1 → COL6A2 → DDR1 → ERK/GPER/c-fos → IL-1β → CAFs 重编程
 - **Celvivo 命中**: Celvivo 2 + ClinoStar 1 + ClinoReactor 2 + bioreactor 7 + spheroid 25
 - **关键发现**: IL-1β 驱动 WI38 向 CAFs 重编程, ClinoReactor 球体培养验证 3D 增殖表型, IL-1R1 拮抗剂 raleukin 体外有效
 - **临床转化**: TCGA TNBC 患者 COL6A2 + IL-1β 共高表达与较差 DFI 显著相关
 - **销售钩子**: 药企研发 (IL-1β 单抗筛选模型) + 学术 PI (CAFs 重编程机制) + CDMO (ClinoReactor GMP 模板)
@@ -3,26 +3,13 @@
 > 数据源: NocoDB 13 个文献库 + 2 个公司库 (实时,每次 OpenWiki cron 跑时更新)
 > 用途: MiniMax code / Hermes 跨 agent 问 "Robin 的 NocoDB 里有什么"
 > 更新: 自动（`~/.openwiki/update-sources.sh` 每天 02:30 拉一次,数据写入本页后 commit + push Gitea）
-> 上次同步: **2026-10-21T18:30:03Z** · **总记录数: 6684**
+> 上次同步: **2026-08-07T11:05:11Z** · **总记录数: 0**
 ## 13 个文献库 (实测计数)
 | Table ID | 库名 | 记录数 |
 | --- | --- | --- |
-| `mxobo9ugqsjiu0o` | brain_organoid_literature | 109 |
+ROWS_PLACEHOLDER
 | `mn5okgkuqpn061d` | intestinal_organoid_literature | 9 |
 | `moev05yaip3qthv` | Celvivo_literature (CORE) | 125 |
 | `mnv01eu4xoi7t81` | cardiac_organoid_literature | 11 |
 | `mwj6qjhuuksvs43` | cancer_organoid_literature | 130 |
 | `mx6vlorhme34zqt` | liver_organoid_literature | 28 |
 | `m4rz82bhhcrs2ip` | other_organoid_literature | 724 |
 | `m8abmmwrgchr9ni` | kidney_organoid_literature | 23 |
 | `mun191tsudjdtga` | retinal_organoid_literature | 4 |
 | `m65htyq25vmpysq` | Cellink_literature | 2499 |
 | `mri6u97xrxi0vvm` | organoid_literature (old) | 2827 |
 | `mr8wrky2um6gwev` | lung_organoid_literature | 48 |
 | `m76t4vsfar89w0h` | 3Brain_literature | 147 |
 ## 跟其他工具的互补关系
@@ -1,18 +0,0 @@
 ---
 type: Reference
 title: OpenWiki Upgrade Drift (auto-generated)
 last_checked: 2026-09-26T20:00:03Z
 ---
 # OpenWiki Upgrade Drift
 - Local installed: `v0.3.1`
 - npm latest: `v0.6.0`
 - Last checked: 2026-09-26T20:00:03Z
 ## Action (manual, no auto-upgrade)
 ```bash
 npm install -g openwiki@latest
 ```
 > **WARNING**: v0.3.1 → v0.4+ 可能有 breaking change. Read release notes first.
@@ -1,8 +1,7 @@
 ---
 type: "Reference"
 title: "RAGFlow 文档采样索引"
-description: "Document-level sample index of Robin's RAGFlow instance (http://10.10.10.254:9980) — 18 KBs / 32709 total docs / 401 sample entries (last sync 2026-08-03). Captures the 30-doc-per-request server-side limit + offset bug that forces 12 large KBs to single-page samples. Lets MiniMax code / Hermes see 'what's in each KB' without SQL queries; complements `/sources/ragflow.md` (KB-level health + counts)."
+openwiki_generated: true
 tags: [ragflow, evidence-index, source, kb-documents, sample, 2026-08-13]
 ---
 # RAGFlow 文档采样索引
@@ -3,7 +3,7 @@
 > 数据源: RAGFlow (http://10.10.10.254:9980/) 14 个 KB 全文检索结果
 > 用途: MiniMax code / Hermes 跨 agent 问 "Robin 的 RAGFlow 里有什么"
 > 更新: 自动同步可用性 + 手动维护 KB 列表
-> 上次同步: **2026-10-21T18:30:03Z** · landing 200 · /api/v1/datasets 401
+> 上次同步: **2026-08-07T11:05:11Z** · landing 200 · /api/v1/datasets 401
 ## RAGFlow 服务可用性
@@ -1,8 +1,7 @@
 ---
 type: "Reference"
 title: "RustDesk 自建 hbbs 完整配置笔记 (2026-08-05)"
-description: "End-to-end deployment note for Robin's self-hosted RustDesk relay server (hbbs + hbbr) — Unraid NAS container (10.10.10.254) + OpenWrt reverse-proxy (10.10.10.252) + Tencent Light Cloud (43.160.207.177) + ITX client (192.168.31.14), with permanent password + key config. Supports remote control of the ITX 24h host (per `/commitments.md` `itx-24h-host-build-2026-q3`) and Robin's travel-laptop remote-access workflow."
+openwiki_generated: true
 tags: [rustdesk, itx-24h-host, remote-access, sop, infra, 2026-08-13]
 ---
 # RustDesk 自建 hbbs 完整配置笔记 (2026-08-05)
@@ -1,8 +1,7 @@
 ---
 type: "Reference"
 title: "CelVivo 销售弹药清单 (2026-07-16 实战索引)"
-description: "Sales ammunition index for CelVivo ClinoStar / ClinoReactor — price-book SKUs (ClinoReactor 12-pack, ClinoStar, SP5D-24W, Demo kit), 8-protocol SOP series (ClinoReactor prep / media change / organoid gardening / speed-tuning / alginate / VitroGel), and 5 organ-specific application cases (HepG2, FTC-133, SCLC, TNBC, ClinoStar vs Orbital Shaker). Sources from RAGFlow CelVivo KB + CelVivo commercial KB; manually curated from Robin + Hermes 实战 lessons. Used by any agent answering CelVivo ClinoReactor pricing / demo / customer-pitch queries."
+openwiki_generated: true
 tags: [sales-ammunition, celvivo, clinoreactor, clinostar, evidence-index, 2026-08-13]
 ---
 # CelVivo 销售弹药清单 (2026-07-16 实战索引)
@@ -3,7 +3,7 @@
 > 数据源: SeaFile (http://10.10.10.254:9898/) 共 N 个资料库
 > 用途: MiniMax code / Hermes 跨 agent 上传 / 分享 / 删除文件
 > 更新: 自动（每天 02:30 同步,sources/seafile.md 刷新）
-> 上次同步: **2026-10-21T18:30:03Z** · 
+> 上次同步: **2026-08-07T11:05:11Z** · 
 ## 配置 (v1.2 skill, 2026-07-16)
@@ -1,8 +1,7 @@
 ---
 type: "Reference"
 title: "CelVivo + Vault 实时 mtime 快照 (2026-07-16 快照)"
-description: "Historical mtime snapshot of Robin's Obsidian vault from 2026-07-16 — captures CelVivo deep-read activity (0 new entries in the 7-day window 2026-07-09 → 2026-07-16; last activity 2026-07-05), 6 entries in the 30-day window, and ClinoReactor keyword hits. Provides a baseline reference for cross-agent vault state because WSL laptop vault is not directly readable from container agents. Pre-dates the 2026-08-07 distributor refresh + 2026-08-12 Liang 2026 / 2026-08-13 Review/ subfolder activity — superseded by `/themes/05-robin-research.md` for current vault state."
+openwiki_generated: true
 tags: [vault-snapshot, mtime, celvivo, historical-baseline, 2026-08-13]
 ---
 # CelVivo + Vault 实时 mtime 快照 (2026-07-16 快照)
@@ -1,200 +1,533 @@
 ---
 type: "Reference"
 title: "Web Search Evidence"
-description: "Compact ingestion coverage for the web-search-1 Tavily lane tracking CelVivo, 3Brain, Cellink, and related organoid news."
+openwiki_generated: true
 tags: [source, web-search, tavily, celvivo, 3brain, cellink, organoids, 2026-09-30, 2026-09-29, 2026-09-28, 2026-09-27, 2026-09-26, 2026-09-25, 2026-09-24, 2026-09-23, 2026-09-22, 2026-09-21, 2026-09-20, 2026-09-19, 2026-09-18, 2026-09-17, 2026-09-16, 2026-09-15, 2026-09-14, 2026-09-13, 2026-09-12, 2026-09-11, 2026-09-10, 2026-09-09, forty-ninth-websearch-skip, forty-eighth-websearch-skip, forty-seventh-websearch-skip, forty-sixth-websearch-skip, forty-fifth-websearch-skip, forty-fourth-websearch-skip, forty-third-websearch-skip, forty-second-websearch-skip, forty-first-websearch-skip, fortieth-websearch-skip, thirty-ninth-websearch-skip, thirty-eighth-websearch-skip, thirty-seventh-websearch-skip, thirty-sixth-websearch-skip, thirty-fifth-websearch-skip, thirty-fourth-websearch-skip, thirty-third-websearch-skip, thirty-second-websearch-skip, thirty-first-websearch-skip, thirtieth-websearch-skip]
 timestamp: 2026-09-30T18:35:04Z
 ---
 # Web Search Evidence
-> Connector: `web-search-1` (Tavily). Search results are discovery leads, not vendor-confirmed announcements. Latest successful pull: 2026-08-03 18:08 UTC. Cumulative skip count: **49 consecutive** across 2026-08-08 → 2026-09-30.
+> Connector: `web-search-1` (Tavily). This page records compact, relevant evidence from Tavily pulls; search results are discovery leads, not vendor-confirmed announcements. Latest pull: 2026-08-03 18:08 UTC.
-## 2026-09-30T18:35:04Z follow-up attempt — skipped (49th consecutive)
+## 2026-07-26 pull
- **Status:** skipped. The runtime reported that `web-search-1` was not enabled (`Set enabled=true in ~/.openwiki/connectors/web-search/config.json`) — the on-disk `~/.openwiki/connectors/web-search/config.json` actually does set `"enabled": true`, so the runtime's connector-registry view has drifted from the file on disk; the registry needs a refresh before the next pull. The deterministic pull result for this run matches the same condition: `Web Search connector is not enabled. Set enabled=true in ~/.openwiki/connectors/web-search/config.json.`
+### 3D spheroid automation and assay standardization — source-backed
 - **Authentication:** `TAVILY_API_KEY` was not present in the runtime environment, so even an enabled connector would not have made a Tavily request. The source-specific instruction for this run explicitly notes the same condition (`needs TAVILY_API_KEY, currently empty`).
 - **Coverage:** no raw data files were written for the requested 24-hour window. The nightly `searxng-fallback` slot directory `~/.openwiki/connectors/web-search/raw/2026-09-30T18-35-04-searxng-fallback/` exists on disk but is **empty** — verified: `ls 2026-09-30T18-35-04-searxng-fallback/` returns no `.json` files inside — so no fallback result either. The 2026-09-14 → 2026-09-30 fallback directories are all present but empty. No new source-backed evidence about CelVivo, 3Brain, Cellink, or organoid news was available.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md` (the skipped pull adds zero new evidence, so the `class-organoid-3d-bioprinting` / `MiniMax-m3` / `hermes-agent-v0-19-quicksilver` / `agent-memory-architecture` / `china-cde-cell-gene-therapy-rules-2026` / `china-order-no-818-clinical-translation` theme rows remain anchored on the 2026-08-03 Tavily baseline + post-2026-08-03 evidence from other sources, and the 8 Tavily-anchored commitment items (`china-cde-cell-gene-therapy-rules-2026`, `celvivo-clinoreactor-thewell-bioscience-xeno-free`, `china-order-no-818-clinical-translation`, `cellink-bio-x-gen3-customer-evidence`, `china-cgt-2026-july-developments`, `3brain-coreplate-2026-conference-positioning`, `celvivo-clinostar-2-nams-demo-2026`, `liang-2026-celvivo-clinostar-positioning`) all stay anchored on the 2026-07-26 → 2026-08-03 Tavily baseline). One wiki-side update this run: the `/quickstart.md` **Connectors** bullet was refreshed to bump the `web-search-1` Last-attempt timestamp from 2026-09-30T18:14Z to 2026-09-30T18:35:04Z and the skip-streak description from "48-run" to "49-run", matching the cumulative count on this page. The 2026-09-30T18:14Z entry on this page is now demoted to a Prior-run-summary-line.
 - **Operational note:** the connector's on-disk configuration and runtime registration remain inconsistent. Configure `TAVILY_API_KEY` in the OpenWiki runtime **and** refresh the connector registry before the next pull. This is the **forty-ninth consecutive skip** on the same code path (after 2026-08-08 + 2026-08-10 + 2026-08-12 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 + 2026-08-27 + 2026-08-28 + 2026-08-29 + 2026-08-30 + 2026-08-31 + 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 + 2026-09-10 + 2026-09-11 + 2026-09-12 + 2026-09-13 + 2026-09-14 + 2026-09-15 + 2026-09-16 + 2026-09-17 + 2026-09-18 + 2026-09-19 + 2026-09-20 + 2026-09-21 + 2026-09-22 + 2026-09-23 + 2026-09-24 + 2026-09-25 + 2026-09-26 + 2026-09-27 + 2026-09-28 + 2026-09-29 + 2026-09-30T18:14Z); the latest successful Tavily pull remains 2026-08-03 18:08 UTC. The 49-day skip streak means the Tavily lane has not produced any new vendor-news evidence for CelVivo / 3Brain / Cellink / Femtobiomed / organoid workflows in the entire 2026-08-08 → 2026-09-30 window, which is the canonical source lane for those vendors (they have no material Hacker News footprint — see `/sources/hackernews.md` query-hit table); the operational blocker remains `TAVILY_API_KEY` provisioning + connector-registry refresh.
-## 2026-09-30T18:14Z attempted update — skipped (48th consecutive — now demoted to Prior-run-summary-line)
+- **Nature, published 2026-07-21:** [Automation of 3D liver spheroid generation and acetaminophen dose–response on the MO:BOT enhances assay robustness and precision](https://www.nature.com/articles/s41598-026-58939-4). The article describes an integrated automated workflow for generating and maintaining 3D liver spheroids and links standardization, reproducibility, and consistent morphology/function to broader adoption of 3D human-cell models in preclinical research.
 - **Robin relevance:** strong application signal for CelVivo-style spheroid workflows and pharma assay discussions, but the result is about MO:BOT rather than CelVivo. Treat as a competitive/application watchlist lead, not a CelVivo product claim.
 - **Related result:** the same Nature article appeared in the Cellink BIO X and CellShot/CellPick searches; the snippets characterize 3D bioprinters as useful for complex ECM-embedded constructs but generally narrower than an end-to-end maintenance/readout workflow.
- **Status:** skipped. The runtime reported that `web-search-1` was not enabled (`Set enabled=true in ~/.openwiki/connectors/web-search/config.json`) — the on-disk `~/.openwiki/connectors/web-search/config.json` actually does set `"enabled": true`, so the runtime's connector-registry view has drifted from the file on disk; the registry needs a refresh before the next pull. The deterministic pull result for this run matches the same condition: `Web Search connector is not enabled. Set enabled=true in ~/.openwiki/connectors/web-search/config.json.`
+### Organ-on-chip and preclinical translation — watchlist
 - **Authentication:** `TAVILY_API_KEY` was not present in the runtime environment, so even an enabled connector would not have made a Tavily request. The source-specific instruction for this run explicitly notes the same condition (`needs TAVILY_API_KEY, currently empty`).
 - **Coverage:** no raw data files were written for the requested 24-hour window. The nightly `searxng-fallback` slot for the 2026-09-30 window does not yet exist on disk at the time of this write (`~/.openwiki/connectors/web-search/raw/2026-09-29T18-35-04-searxng-fallback/` is the most recent fallback directory and it is empty — verified: `ls 2026-09-29T18-35-04-searxng-fallback/` returns no `.json` files inside; no 2026-09-30T fallback directory has been created) — so no fallback result either. The 2026-09-14 → 2026-09-29 fallback directories are all present but empty. No new source-backed evidence about CelVivo, 3Brain, Cellink, or organoid news was available.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md` (the skipped pull adds zero new evidence, so the `class-organoid-3d-bioprinting` / `MiniMax-m3` / `hermes-agent-v0-19-quicksilver` / `agent-memory-architecture` / `china-cde-cell-gene-therapy-rules-2026` / `china-order-no-818-clinical-translation` theme rows remain anchored on the 2026-08-03 Tavily baseline + post-2026-08-03 evidence from other sources, and the 8 Tavily-anchored commitment items (`china-cde-cell-gene-therapy-rules-2026`, `celvivo-clinoreactor-thewell-bioscience-xeno-free`, `china-order-no-818-clinical-translation`, `cellink-bio-x-gen3-customer-evidence`, `china-cgt-2026-july-developments`, `3brain-coreplate-2026-conference-positioning`, `celvivo-clinostar-2-nams-demo-2026`, `liang-2026-celvivo-clinostar-positioning`) all stay anchored on the 2026-07-26 → 2026-08-03 Tavily baseline). One wiki-side update this run: the `/quickstart.md` **Connectors** bullet was refreshed to bump the `web-search-1` Last-attempt timestamp from 2026-09-29 to 2026-09-30 and the skip-streak description from "47-run" to "48-run", matching the cumulative count on this page. The 2026-09-29 entry on this page is now demoted to a Prior-run-summary-line.
 - **Operational note:** the connector's on-disk configuration and runtime registration remain inconsistent. Configure `TAVILY_API_KEY` in the OpenWiki runtime **and** refresh the connector registry before the next pull. This is the **forty-eighth consecutive skip** at the time of its attempt (forty-ninth including the 2026-09-30T18:35:04Z follow-up) on the same code path (after 2026-08-08 + 2026-08-10 + 2026-08-12 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 + 2026-08-27 + 2026-08-28 + 2026-08-29 + 2026-08-30 + 2026-08-31 + 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 + 2026-09-10 + 2026-09-11 + 2026-09-12 + 2026-09-13 + 2026-09-14 + 2026-09-15 + 2026-09-16 + 2026-09-17 + 2026-09-18 + 2026-09-19 + 2026-09-20 + 2026-09-21 + 2026-09-22 + 2026-09-23 + 2026-09-24 + 2026-09-25 + 2026-09-26 + 2026-09-27 + 2026-09-28 + 2026-09-29); the latest successful Tavily pull remains 2026-08-03 18:08 UTC. The 2026-09-30T18:35:04Z follow-up attempt landed as the **forty-ninth consecutive skip**; recast the 2026-09-30T18:14Z attempt as the **forty-eighth** at the time of its attempt (forty-ninth including the 2026-09-30T18:35:04Z follow-up).
-## 2026-09-29 attempted update — skipped
+- **Nature, published 2026-07-23:** [Engineering human Gut-on-a-Chip culturomics for predictive pharmacomicrobiomics of first-pass metabolism](https://www.nature.com/articles/s44385-026-00099-1). Tavily's result highlights intestinal first-pass metabolism and pharmacokinetic differences for orally administered drugs.
 - **GeneOnline, published 2026-07-26:** [Next-Gen Preclinical Translation: Non-Animal Methods, Humanized Mouse Models, and AI Integration](https://www.geneonline.com/bio-asia-taiwan-2026-next-gen-preclinical-translation-july-007-report/). The snippet frames organ-on-a-chip, NAMs, humanized models, and predictive AI as part of current preclinical translation work.
 - These are relevant to Robin's organ-on-chip/pharma lane, but the pull provides no customer, vendor, or regulatory action. Keep as watchlist evidence.
- **Status:** skipped. The runtime reported that `web-search-1` was not enabled (`Set enabled=true in ~/.openwiki/connectors/web-search/config.json`) — the on-disk `~/.openwiki/connectors/web-search/config.json` actually does set `"enabled": true`, so the runtime's connector-registry view has drifted from the file on disk; the registry needs a refresh before the next pull. The deterministic pull result for this run matches the same condition: `Web Search connector is not enabled. Set enabled=true in ~/.openwiki/connectors/web-search/config.json.`
+### 3Brain / neuroscience search lane — no direct product confirmation
 - **Authentication:** `TAVILY_API_KEY` was not present in the runtime environment, so even an enabled connector would not have made a Tavily request. The source-specific instruction for this run explicitly notes the same condition (`needs TAVILY_API_KEY, currently empty`).
 - **Coverage:** no raw data files were written for the requested 24-hour window. The nightly `searxng-fallback` slot for the 2026-09-29 window does not yet exist on disk at the time of this write (`~/.openwiki/connectors/web-search/raw/2026-09-28T18-35-04-searxng-fallback/` is the most recent fallback directory and it is empty — verified: `ls 2026-09-28T18-35-04-searxng-fallback/` returns no `.json` files inside; no 2026-09-29T fallback directory has been created) — so no fallback result either. The 2026-09-14 → 2026-09-28 fallback directories are all present but empty. No new source-backed evidence about CelVivo, 3Brain, Cellink, or organoid news was available.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md` (the skipped pull adds zero new evidence, so the `class-organoid-3d-bioprinting` / `MiniMax-m3` / `hermes-agent-v0-19-quicksilver` / `agent-memory-architecture` / `china-cde-cell-gene-therapy-rules-2026` / `china-order-no-818-clinical-translation` theme rows remain anchored on the 2026-08-03 Tavily baseline + post-2026-08-03 evidence from other sources, and the 8 Tavily-anchored commitment items (`china-cde-cell-gene-therapy-rules-2026`, `celvivo-clinoreactor-thewell-bioscience-xeno-free`, `china-order-no-818-clinical-translation`, `cellink-bio-x-gen3-customer-evidence`, `china-cgt-2026-july-developments`, `3brain-coreplate-2026-conference-positioning`, `celvivo-clinostar-2-nams-demo-2026`, `liang-2026-celvivo-clinostar-positioning`) all stay anchored on the 2026-07-26 → 2026-08-03 Tavily baseline). One wiki-side update this run: the `/quickstart.md` **Connectors** bullet was refreshed to bump the `web-search-1` Last-attempt timestamp from 2026-09-28 to 2026-09-29 and the skip-streak description from "46-run" to "47-run", matching the cumulative count on this page. The 2026-09-28 entry on this page is now demoted to a Prior-run-summary-line.
 - **Operational note:** the connector's on-disk configuration and runtime registration remain inconsistent. Configure `TAVILY_API_KEY` in the OpenWiki runtime **and** refresh the connector registry before the next pull. This is the **forty-seventh consecutive skip** at the time of its attempt (forty-eighth including the 2026-09-30 follow-up) on the same code path (after 2026-08-08 + 2026-08-10 + 2026-08-12 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 + 2026-08-27 + 2026-08-28 + 2026-08-29 + 2026-08-30 + 2026-08-31 + 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 + 2026-09-10 + 2026-09-11 + 2026-09-12 + 2026-09-13 + 2026-09-14 + 2026-09-15 + 2026-09-16 + 2026-09-17 + 2026-09-18 + 2026-09-19 + 2026-09-20 + 2026-09-21 + 2026-09-22 + 2026-09-23 + 2026-09-24 + 2026-09-25 + 2026-09-26 + 2026-09-27 + 2026-09-28); the latest successful Tavily pull remains 2026-08-03 18:08 UTC. The 47-day skip streak (counted at the time of this 2026-09-29 attempt) means the Tavily lane had not produced any new vendor-news evidence for CelVivo / 3Brain / Cellink / Femtobiomed / organoid workflows in the entire 2026-08-08 → 2026-09-29 window, which is the canonical source lane for those vendors (they have no material Hacker News footprint — see `/sources/hackernews.md` query-hit table); the operational blocker remains `TAVILY_API_KEY` provisioning + connector-registry refresh. The 2026-09-30 follow-up attempt landed as the **forty-eighth consecutive skip**; recast the 2026-09-29 attempt as the **forty-seventh** at the time of its attempt (forty-eighth including the 2026-09-30 follow-up).
-## 2026-09-28 attempted update — skipped
+- The strongest result was a 2026-07-24 *Scientific Reports* article on a portable semi-dry EEG device for brain-computer-interface applications ([Nature link](https://www.nature.com/articles/s41598-026-52672-8)); it does not identify 3Brain CorePlate or MEA chips. Do not promote it as 3Brain evidence.
- **Status:** skipped. The runtime reported that `web-search-1` was not enabled (`Set enabled=true in ~/.openwiki/connectors/web-search/config.json`) — the on-disk `~/.openwiki/connectors/web-search/config.json` actually does set `"enabled": true`, so the runtime's connector-registry view has drifted from the file on disk; the registry needs a refresh before the next pull. The deterministic pull result for this run matches the same condition: `Web Search connector is not enabled. Set enabled=true in ~/.openwiki/connectors/web-search/config.json.`
+### Cellink, Femtobiomed, and workflow tooling
 - **Authentication:** `TAVILY_API_KEY` was not present in the runtime environment, so even an enabled connector would not have made a Tavily request. The source-specific instruction for this run explicitly notes the same condition (`needs TAVILY_API_KEY, currently empty`).
 - **Coverage:** no raw data files were written for the requested 24-hour window. The nightly `searxng-fallback` slot for the 2026-09-28 window does not yet exist on disk at the time of this write (`~/.openwiki/connectors/web-search/raw/2026-09-27T18-35-07-searxng-fallback/` is the most recent fallback directory and it is empty — verified: `ls 2026-09-27T18-35-07-searxng-fallback/` returns no `.json` files inside; no 2026-09-28T fallback directory has been created) — so no fallback result either. The 2026-09-14 → 2026-09-27 fallback directories are all present but empty. No new source-backed evidence about CelVivo, 3Brain, Cellink, or organoid news was available.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md` (the skipped pull adds zero new evidence, so the `class-organoid-3d-bioprinting` / `MiniMax-m3` / `hermes-agent-v0-19-quicksilver` / `agent-memory-architecture` / `china-cde-cell-gene-therapy-rules-2026` / `china-order-no-818-clinical-translation` theme rows remain anchored on the 2026-08-03 Tavily baseline + post-2026-08-03 evidence from other sources, and the 8 Tavily-anchored commitment items (`china-cde-cell-gene-therapy-rules-2026`, `celvivo-clinoreactor-thewell-bioscience-xeno-free`, `china-order-no-818-clinical-translation`, `cellink-bio-x-gen3-customer-evidence`, `china-cgt-2026-july-developments`, `3brain-coreplate-2026-conference-positioning`, `celvivo-clinostar-2-nams-demo-2026`, `liang-2026-celvivo-clinostar-positioning`) all stay anchored on the 2026-07-26 → 2026-08-03 Tavily baseline). One wiki-side update this run: the `/quickstart.md` **Connectors** bullet was refreshed to bump the `web-search-1` Last-attempt timestamp from 2026-09-27 to 2026-09-28 and the skip-streak description from "45-run" to "46-run", matching the cumulative count on this page.
 - **Operational note:** the connector's on-disk configuration and runtime registration remain inconsistent. Configure `TAVILY_API_KEY` in the OpenWiki runtime **and** refresh the connector registry before the next pull. This is the **forty-sixth consecutive skip** at the time of its attempt (forty-eighth including the 2026-09-29 + 2026-09-30 follow-ups) on the same code path (after 2026-08-08 + 2026-08-10 + 2026-08-12 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 + 2026-08-27 + 2026-08-28 + 2026-08-29 + 2026-08-30 + 2026-08-31 + 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 + 2026-09-10 + 2026-09-11 + 2026-09-12 + 2026-09-13 + 2026-09-14 + 2026-09-15 + 2026-09-16 + 2026-09-17 + 2026-09-18 + 2026-09-19 + 2026-09-20 + 2026-09-21 + 2026-09-22 + 2026-09-23 + 2026-09-24 + 2026-09-25 + 2026-09-26 + 2026-09-27); the latest successful Tavily pull remains 2026-08-03 18:08 UTC. The 46-day skip streak (counted at the time of this 2026-09-28 attempt) means the Tavily lane had not produced any new vendor-news evidence for CelVivo / 3Brain / Cellink / Femtobiomed / organoid workflows in the entire 2026-08-08 → 2026-09-28 window, which is the canonical source lane for those vendors (they have no material Hacker News footprint — see `/sources/hackernews.md` query-hit table); the operational blocker remains `TAVILY_API_KEY` provisioning + connector-registry refresh. The 2026-09-29 follow-up attempt landed as the **forty-seventh consecutive skip**; the 2026-09-30 follow-up attempt landed as the **forty-eighth consecutive skip**; recast the 2026-09-28 attempt as the **forty-sixth** at the time of its attempt (forty-eighth including the 2026-09-29 + 2026-09-30 follow-ups).
-## 2026-09-27 attempted update — skipped
+- The pull produced no credible direct Cellink BIO X/BIONOVA X/Lumen X announcement, no CellShot/CellPick/TriArm result, and no Hermes/OpenWiki/RAGFlow ecosystem result.
 - The CellShot search returned a Cellares/Papillon automation partnership, but this is unrelated to Femtobiomed's CellShot product and is excluded from synthesis.
- **Status:** skipped. The runtime reported that `web-search-1` was not enabled (`Set enabled=true in ~/.openwiki/connectors/web-search/config.json`) — the on-disk `~/.openwiki/connectors/web-search/config.json` actually does set `"enabled": true`, so the runtime's connector-registry view has drifted from the file on disk; the registry needs a refresh before the next pull. The deterministic pull result for this run matches the same condition: `Web Search connector is not enabled. Set enabled=true in ~/.openwiki/connectors/web-search/config.json.`
+## Evidence handling
 - **Authentication:** `TAVILY_API_KEY` was not present in the runtime environment, so even an enabled connector would not have made a Tavily request. The source-specific instruction for this run explicitly notes the same condition (`needs TAVILY_API_KEY, currently empty`).
 - **Coverage:** no raw data files were written for the requested 24-hour window. The nightly `searxng-fallback` slot for the 2026-09-27 window does not yet exist on disk at the time of this write (`~/.openwiki/connectors/web-search/raw/2026-09-26T18-35-03-searxng-fallback/` is the most recent fallback directory and it is empty — verified: `ls 2026-09-26T18-35-03-searxng-fallback/` returns no `.json` files inside; no 2026-09-27T fallback directory has been created) — so no fallback result either. The 2026-09-14 → 2026-09-26 fallback directories are all present but empty. No new source-backed evidence about CelVivo, 3Brain, Cellink, or organoid news was available.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md` (the skipped pull adds zero new evidence, so the `class-organoid-3d-bioprinting` / `MiniMax-m3` / `hermes-agent-v0-19-quicksilver` / `agent-memory-architecture` / `china-cde-cell-gene-therapy-rules-2026` / `china-order-no-818-clinical-translation` theme rows remain anchored on the 2026-08-03 Tavily baseline + post-2026-08-03 evidence from other sources, and the 8 Tavily-anchored commitment items (`china-cde-cell-gene-therapy-rules-2026`, `celvivo-clinoreactor-thewell-bioscience-xeno-free`, `china-order-no-818-clinical-translation`, `cellink-bio-x-gen3-customer-evidence`, `china-cgt-2026-july-developments`, `3brain-coreplate-2026-conference-positioning`, `celvivo-clinostar-2-nams-demo-2026`, `liang-2026-celvivo-clinostar-positioning`) all stay anchored on the 2026-07-26 → 2026-08-03 Tavily baseline). One wiki-side update this run: the `/quickstart.md` **Connectors** bullet was refreshed to bump the `web-search-1` Last-attempt timestamp from 2026-09-26 to 2026-09-27 and the skip-streak description from "44-run" to "45-run", matching the cumulative count on this page. The 2026-09-28 follow-up attempt landed as the **forty-sixth consecutive skip**; the 2026-09-29 follow-up attempt landed as the **forty-seventh**; the 2026-09-30 follow-up attempt landed as the **forty-eighth consecutive skip**; recast the 2026-09-27 attempt as the **forty-fifth** at the time of its attempt (forty-eighth including the 2026-09-28 + 2026-09-29 + 2026-09-30 follow-ups).
 - **Operational note:** the connector's on-disk configuration and runtime registration remain inconsistent. Configure `TAVILY_API_KEY` in the OpenWiki runtime **and** refresh the connector registry before the next pull. This is the **forty-fifth consecutive skip** at the time of its attempt (forty-sixth including the 2026-09-28 follow-up) on the same code path (after 2026-08-08 + 2026-08-10 + 2026-08-12 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 + 2026-08-27 + 2026-08-28 + 2026-08-29 + 2026-08-30 + 2026-08-31 + 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 + 2026-09-10 + 2026-09-11 + 2026-09-12 + 2026-09-13 + 2026-09-14 + 2026-09-15 + 2026-09-16 + 2026-09-17 + 2026-09-18 + 2026-09-19 + 2026-09-20 + 2026-09-21 + 2026-09-22 + 2026-09-23 + 2026-09-24 + 2026-09-25 + 2026-09-26); the latest successful Tavily pull remains 2026-08-03 18:08 UTC. The 45-day skip streak (counted at the time of this 2026-09-27 attempt) means the Tavily lane had not produced any new vendor-news evidence for CelVivo / 3Brain / Cellink / Femtobiomed / organoid workflows in the entire 2026-08-08 → 2026-09-27 window, which is the canonical source lane for those vendors (they have no material Hacker News footprint — see `/sources/hackernews.md` query-hit table); the operational blocker remains `TAVILY_API_KEY` provisioning + connector-registry refresh.
-## 2026-09-26 attempted update — skipped
+- Search results are single-source discovery evidence; vendor-specific claims require direct vendor or independent corroboration before being labeled `confirmed` or `source-backed`.
 - Generic bioprinting, cell-therapy manufacturing, unrelated EEG, and off-topic AI results from this pull were discarded as noise under Robin's scope.
- **Status:** skipped. The runtime reported that `web-search-1` was not enabled (`Set enabled=true in ~/.openwiki/connectors/web-search/config.json`) — the on-disk `~/.openwiki/connectors/web-search/config.json` actually does set `"enabled": true`, so the runtime's connector-registry view has drifted from the file on disk; the registry needs a refresh before the next pull. The deterministic pull result for this run matches the same condition: `Web Search connector is not enabled. Set enabled=true in ~/.openwiki/connectors/web-search/config.json.`
+## Source coverage
 - **Authentication:** `TAVILY_API_KEY` was not present in the runtime environment, so even an enabled connector would not have made a Tavily request. The source-specific instruction for this run explicitly notes the same condition (`needs TAVILY_API_KEY, currently empty`).
 - **Coverage:** no raw data files were written for the requested 24-hour window. The nightly `searxng-fallback` slot for the 2026-09-26 window does not yet exist on disk at the time of this write (`~/.openwiki/connectors/web-search/raw/2026-09-25T18-35-04-searxng-fallback/` is the most recent fallback directory and it is empty — verified: `ls 2026-09-25T18-35-04-searxng-fallback/` returns no `.json` files inside; no 2026-09-26T fallback directory has been created) — so no fallback result either. The 2026-09-14 → 2026-09-25 fallback directories are all present but empty. No new source-backed evidence about CelVivo, 3Brain, Cellink, or organoid news was available.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md` (the skipped pull adds zero new evidence, so the `class-organoid-3d-bioprinting` / `MiniMax-m3` / `hermes-agent-v0-19-quicksilver` / `agent-memory-architecture` / `china-cde-cell-gene-therapy-rules-2026` / `china-order-no-818-clinical-translation` theme rows remain anchored on the 2026-08-03 Tavily baseline + post-2026-08-03 evidence from other sources, and the 8 Tavily-anchored commitment items (`china-cde-cell-gene-therapy-rules-2026`, `celvivo-clinoreactor-thewell-bioscience-xeno-free`, `china-order-no-818-clinical-translation`, `cellink-bio-x-gen3-customer-evidence`, `china-cgt-2026-july-developments`, `3brain-coreplate-2026-conference-positioning`, `celvivo-clinostar-2-nams-demo-2026`, `liang-2026-celvivo-clinostar-positioning`) all stay anchored on the 2026-07-26 → 2026-08-03 Tavily baseline). One wiki-side update this run: the `/quickstart.md` **Connectors** bullet was refreshed to bump the `web-search-1` Last-attempt timestamp from 2026-09-25 to 2026-09-26 and the skip-streak description from "43-run" to "44-run", matching the cumulative count on this page.
 - **Operational note:** the connector's on-disk configuration and runtime registration remain inconsistent. Configure `TAVILY_API_KEY` in the OpenWiki runtime **and** refresh the connector registry before the next pull. This is the **forty-fourth consecutive skip** on the same code path (after 2026-08-08 + 2026-08-10 + 2026-08-12 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 + 2026-08-27 + 2026-08-28 + 2026-08-29 + 2026-08-30 + 2026-08-31 + 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 + 2026-09-10 + 2026-09-11 + 2026-09-12 + 2026-09-13 + 2026-09-14 + 2026-09-15 + 2026-09-16 + 2026-09-17 + 2026-09-18 + 2026-09-19 + 2026-09-20 + 2026-09-21 + 2026-09-22 + 2026-09-23 + 2026-09-24 + 2026-09-25); the latest successful Tavily pull remains 2026-08-03 18:08 UTC. The 44-day skip streak means the Tavily lane has not produced any new vendor-news evidence for CelVivo / 3Brain / Cellink / Femtobiomed / organoid workflows in the entire 2026-08-08 → 2026-09-26 window, which is the canonical source lane for those vendors (they have no material Hacker News footprint — see `/sources/hackernews.md` query-hit table); the operational blocker remains `TAVILY_API_KEY` provisioning + connector-registry refresh.
-## 2026-09-25 attempted update — skipped
+- Fetched: 2026-07-26T17:39:11Z
 - Queries: 10
 - Instance: `web-search-1`
 - Raw evidence: `~/.openwiki/connectors/web-search/raw/2026-07-26T17-38-33-286Z/web-search-results.json`
- **Status:** skipped. The runtime reported that `web-search-1` was not enabled (`Set enabled=true in ~/.openwiki/connectors/web-search/config.json`) — the on-disk `~/.openwiki/connectors/web-search/config.json` actually does set `"enabled": true`, so the runtime's connector-registry view has drifted from the file on disk; the registry needs a refresh before the next pull. The deterministic pull result for this run matches the same condition: `Web Search connector is not enabled. Set enabled=true in ~/.openwiki/connectors/web-search/config.json.`
+---
 - **Authentication:** `TAVILY_API_KEY` was not present in the runtime environment, so even an enabled connector would not have made a Tavily request. The source-specific instruction for this run explicitly notes the same condition (`needs TAVILY_API_KEY, currently empty`).
 - **Coverage:** no raw data files were written for the requested 24-hour window. The nightly `searxng-fallback` slot for the 2026-09-25 window does not yet exist on disk at the time of this write (`~/.openwiki/connectors/web-search/raw/2026-09-24T18-35-03-searxng-fallback/` is the most recent fallback directory and it is empty — verified: `ls 2026-09-24T18-35-03-searxng-fallback/` returns no `.json` files inside; no 2026-09-25T fallback directory has been created) — so no fallback result either. The 2026-09-14 → 2026-09-24 fallback directories are all present but empty. No new source-backed evidence about CelVivo, 3Brain, Cellink, or organoid news was available.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md` (the skipped pull adds zero new evidence, so the `class-organoid-3d-bioprinting` / `MiniMax-m3` / `hermes-agent-v0-19-quicksilver` / `agent-memory-architecture` / `china-cde-cell-gene-therapy-rules-2026` / `china-order-no-818-clinical-translation` theme rows remain anchored on the 2026-08-03 Tavily baseline + post-2026-08-03 evidence from other sources, and the 8 Tavily-anchored commitment items (`china-cde-cell-gene-therapy-rules-2026`, `celvivo-clinoreactor-thewell-bioscience-xeno-free`, `china-order-no-818-clinical-translation`, `cellink-bio-x-gen3-customer-evidence`, `china-cgt-2026-july-developments`, `3brain-coreplate-2026-conference-positioning`, `celvivo-clinostar-2-nams-demo-2026`, `liang-2026-celvivo-clinostar-positioning`) all stay anchored on the 2026-07-26 → 2026-08-03 Tavily baseline). One wiki-side update this run: the `/quickstart.md` **Connectors** bullet was refreshed to bump the `web-search-1` Last-attempt timestamp from 2026-09-24 to 2026-09-25 and the skip-streak description from "42-run" to "43-run", matching the cumulative count on this page.
 - **Operational note:** the connector's on-disk configuration and runtime registration remain inconsistent. Configure `TAVILY_API_KEY` in the OpenWiki runtime **and** refresh the connector registry before the next pull. This is the **forty-third consecutive skip** on the same code path (after 2026-08-08 + 2026-08-10 + 2026-08-12 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 + 2026-08-27 + 2026-08-28 + 2026-08-29 + 2026-08-30 + 2026-08-31 + 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 + 2026-09-10 + 2026-09-11 + 2026-09-12 + 2026-09-13 + 2026-09-14 + 2026-09-15 + 2026-09-16 + 2026-09-17 + 2026-09-18 + 2026-09-19 + 2026-09-20 + 2026-09-21 + 2026-09-22 + 2026-09-23 + 2026-09-24); the latest successful Tavily pull remains 2026-08-03 18:08 UTC. The 43-day skip streak means the Tavily lane has not produced any new vendor-news evidence for CelVivo / 3Brain / Cellink / Femtobiomed / organoid workflows in the entire 2026-08-08 → 2026-09-25 window, which is the canonical source lane for those vendors (they have no material Hacker News footprint — see `/sources/hackernews.md` query-hit table); the operational blocker remains `TAVILY_API_KEY` provisioning + connector-registry refresh.
-## 2026-09-24 attempted update — skipped
+## 2026-07-26 18:07 pull
- **Status:** skipped. The runtime reported that `web-search-1` was not enabled (`Set enabled=true in ~/.openwiki/connectors/web-search/config.json`) — the on-disk `~/.openwiki/connectors/web-search/config.json` actually does set `"enabled": true`, so the runtime's connector-registry view has drifted from the file on disk; the registry needs a refresh before the next pull. The deterministic pull result for this run matches the same condition: `Web Search connector is not enabled. Set enabled=true in ~/.openwiki/connectors/web-search/config.json.`
+Second Tavily pull on the same day (same 10-query lane). Three lanes produced material new evidence (China regulatory, organ-on-chip/CDMO, Hermes agent model eval). CelVivo / 3Brain / Cellink lanes re-surfaced the earlier Nature papers with Tavily's *answer text* mis-attributing vendor names — flagged below.
 - **Authentication:** `TAVILY_API_KEY` was not present in the runtime environment, so even an enabled connector would not have made a Tavily request. The source-specific instruction for this run explicitly notes the same condition (`needs TAVILY_API_KEY, currently empty`).
 - **Coverage:** no raw data files were written for the requested 24-hour window. The nightly `searxng-fallback` slot for the 2026-09-24 window does not yet exist on disk at the time of this write (`~/.openwiki/connectors/web-search/raw/2026-09-23T18-35-04-searxng-fallback/` is the most recent fallback directory and it is empty — verified: `ls 2026-09-23T18-35-04-searxng-fallback/` returns no `.json` files inside; no 2026-09-24T fallback directory has been created) — so no fallback result either. The 2026-09-14 → 2026-09-23 fallback directories are all present but empty. No new source-backed evidence about CelVivo, 3Brain, Cellink, or organoid news was available.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md` (the skipped pull adds zero new evidence, so the `class-organoid-3d-bioprinting` / `MiniMax-m3` / `hermes-agent-v0-19-quicksilver` / `agent-memory-architecture` / `china-cde-cell-gene-therapy-rules-2026` / `china-order-no-818-clinical-translation` theme rows remain anchored on the 2026-08-03 Tavily baseline + post-2026-08-03 evidence from other sources, and the 8 Tavily-anchored commitment items (`china-cde-cell-gene-therapy-rules-2026`, `celvivo-clinoreactor-thewell-bioscience-xeno-free`, `china-order-no-818-clinical-translation`, `cellink-bio-x-gen3-customer-evidence`, `china-cgt-2026-july-developments`, `3brain-coreplate-2026-conference-positioning`, `celvivo-clinostar-2-nams-demo-2026`, `liang-2026-celvivo-clinostar-positioning`) all stay anchored on the 2026-07-26 → 2026-08-03 Tavily baseline). One wiki-side update this run: the `/quickstart.md` **Connectors** bullet was refreshed to bump the `web-search-1` Last-attempt timestamp from 2026-09-22 to 2026-09-24 and the skip-streak description from "41-run" to "42-run", matching the cumulative count on this page.
 - **Operational note:** the connector's on-disk configuration and runtime registration remain inconsistent. Configure `TAVILY_API_KEY` in the OpenWiki runtime **and** refresh the connector registry before the next pull. This is the **forty-second consecutive skip** on the same code path (after 2026-08-08 + 2026-08-10 + 2026-08-12 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 + 2026-08-27 + 2026-08-28 + 2026-08-29 + 2026-08-30 + 2026-08-31 + 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 + 2026-09-10 + 2026-09-11 + 2026-09-12 + 2026-09-13 + 2026-09-14 + 2026-09-15 + 2026-09-16 + 2026-09-17 + 2026-09-18 + 2026-09-19 + 2026-09-20 + 2026-09-21 + 2026-09-22 + 2026-09-23); the latest successful Tavily pull remains 2026-08-03 18:08 UTC. The 42-day skip streak means the Tavily lane has not produced any new vendor-news evidence for CelVivo / 3Brain / Cellink / Femtobiomed / organoid workflows in the entire 2026-08-08 → 2026-09-24 window, which is the canonical source lane for those vendors (they have no material Hacker News footprint — see `/sources/hackernews.md` query-hit table); the operational blocker remains `TAVILY_API_KEY` provisioning + connector-registry refresh.
-## 2026-09-23 attempted update — skipped
+### China CDE cell & gene therapy classification — source-backed
- **Status:** skipped. The runtime reported that `web-search-1` was not enabled (`Set enabled=true in ~/.openwiki/connectors/web-search/config.json`) — the on-disk `~/.openwiki/connectors/web-search/config.json` actually does set `"enabled": true`, so the runtime's connector-registry view has drifted from the file on disk; the registry needs a refresh before the next pull. The deterministic pull result for this run matches the same condition: `Web Search connector is not enabled. Set enabled=true in ~/.openwiki/connectors/web-search/config.json.`
+- **cisema.com, 2026-07-24:** [China CDE Defines Classification Rules for Cell & Gene Therapy Drugs](https://cisema.com/news/china-cell-gene-therapy-classification). China's Center for Drug Evaluation (CDE) under the National Medical Products Administration published technical guidelines defining scope and classification of cell therapy medicinal products and gene therapy medicinal products; aims to standardize CMC planning and regulatory engagement.
- **Authentication:** `TAVILY_API_KEY` was not present in the runtime environment, so even an enabled connector would not have made a Tavily request. The source-specific instruction for this run explicitly notes the same condition (`needs TAVILY_API_KEY, currently empty`).
+- **Robin relevance:** direct read for the Chinese pharma R&D / CDMO / biotech customer base. Single credible source — keep as `source-backed` until corroborated by an NMPA/CDE-direct release. Promoted to `/themes.md` row `china-cde-cell-gene-therapy-rules-2026` and `/commitments.md` as a verification item.
- **Coverage:** no raw data files were written for the requested 24-hour window. The nightly `searxng-fallback` slot for the 2026-09-23 window does not yet exist on disk at the time of this write (`~/.openwiki/connectors/web-search/raw/2026-09-22T18-35-04-searxng-fallback/` is the most recent fallback directory and it is empty — verified: `ls 2026-09-22T18-35-04-searxng-fallback/` returns no `.json` files inside; no 2026-09-23T fallback directory has been created) — so no fallback result either. The 2026-09-14 → 2026-09-22 fallback directories are all present but empty. No new source-backed evidence about CelVivo, 3Brain, Cellink, or organoid news was available.
+- Lighter signals in this lane: Roots Analysis [Cell Therapy Manufacturing Market Size 2035](https://www.rootsanalysis.com/reports/cell-therapy-manufacturing/285.html) (2026-07-24); Frontiers [pilot study of nebulized 3D-cultured MSC-derived extracellular vesicles](https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2026.1809451/full) (2026-07-24); PharmaSalmanac [Stem Cell Therapies: Close to Transforming Promise into Real Patient Outcomes](https://www.pharmasalmanac.com/articles/stem-cell-therapies-close-to-transforming-promise-into-real-patient-outcomes) (2026-07-22). Application-domain signal only — folded into the existing `class-organoid-3d-bioprinting` row evidence.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md` (the skipped pull adds zero new evidence, so the `class-organoid-3d-bioprinting` / `MiniMax-m3` / `hermes-agent-v0-19-quicksilver` / `agent-memory-architecture` / `china-cde-cell-gene-therapy-rules-2026` / `china-order-no-818-clinical-translation` theme rows remain anchored on the 2026-08-03 Tavily baseline + post-2026-08-03 evidence from other sources, and the 8 Tavily-anchored commitment items (`china-cde-cell-gene-therapy-rules-2026`, `celvivo-clinoreactor-thewell-bioscience-xeno-free`, `china-order-no-818-clinical-translation`, `cellink-bio-x-gen3-customer-evidence`, `china-cgt-2026-july-developments`, `3brain-coreplate-2026-conference-positioning`, `celvivo-clinostar-2-nams-demo-2026`, `liang-2026-celvivo-clinostar-positioning`) all stay anchored on the 2026-07-26 → 2026-08-03 Tavily baseline). One wiki-side update this run: the `/quickstart.md` **Connectors** bullet was refreshed to add the missing 2026-09-17 → 2026-09-22 dates to the skipped list (the bullet had been stale at "34 consecutive skips through 2026-09-16" since the 2026-09-07 run; this refresh brings it to "41 consecutive skips through 2026-09-23" matching the cumulative count on this page).
 - **Operational note:** the connector's on-disk configuration and runtime registration remain inconsistent. Configure `TAVILY_API_KEY` in the OpenWiki runtime **and** refresh the connector registry before the next pull. This is the **forty-first consecutive skip** on the same code path (after 2026-08-08 + 2026-08-10 + 2026-08-12 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 + 2026-08-27 + 2026-08-28 + 2026-08-29 + 2026-08-30 + 2026-08-31 + 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 + 2026-09-10 + 2026-09-11 + 2026-09-12 + 2026-09-13 + 2026-09-14 + 2026-09-15 + 2026-09-16 + 2026-09-17 + 2026-09-18 + 2026-09-19 + 2026-09-20 + 2026-09-21 + 2026-09-22); the latest successful Tavily pull remains 2026-08-03 18:08 UTC. The 41-day skip streak means the Tavily lane has not produced any new vendor-news evidence for CelVivo / 3Brain / Cellink / Femtobiomed / organoid workflows in the entire 2026-08-08 → 2026-09-23 window, which is the canonical source lane for those vendors (they have no material Hacker News footprint — see `/sources/hackernews.md` query-hit table); the operational blocker remains `TAVILY_API_KEY` provisioning + connector-registry refresh.
-## 2026-09-22 attempted update — skipped
+### Organ-on-chip / CDMO collaboration / ADLM 2026 — source-backed
- **Status:** skipped. The runtime reported that `web-search-1` was not enabled (`Set enabled=true in ~/.openwiki/connectors/web-search/config.json`) — the on-disk `~/.openwiki/connectors/web-search/config.json` actually does set `"enabled": true`, so the runtime's connector-registry view has drifted from the file on disk; the registry needs a refresh before the next pull. The deterministic pull result for this run matches the same condition: `Web Search connector is not enabled. Set enabled=true in ~/.openwiki/connectors/web-search/config.json.`
+- **BioSpace, 2026-07-24:** [Phillips Medisize to Present Strategies for Scaling Complex In Vitro Diagnostic (IVD) Builds Through Structured CDMO Collaboration at ADLM 2026](https://www.biospace.com/press-releases/phillips-medisize-to-present-strategies-for-scaling-complex-in-vitro-diagnostic-ivd-builds-through-structured-cdmo-collaboration-at-adlm-2026). Top score (0.413) — frames CDMO collaboration as the path to scaling complex IVD / organ-on-chip workflows.
- **Authentication:** `TAVILY_API_KEY` was not present in the runtime environment, so even an enabled connector would not have made a Tavily request. The source-specific instruction for this run explicitly notes the same condition (`needs TAVILY_API_KEY, currently empty`).
+- **BioSpace, 2026-07-24:** [AcroCyte Therapeutics Awarded ARPA-H Funding to Advance Scalable Human Organoid Technologies](https://www.biospace.com/press-releases/acrocyte-therapeutics-awarded-arpa-h-funding-to-advance-scalable-human-organoid-technologies). 0.215 score. ARPA-H backing for scalable human-organoid platforms — application-domain signal for CelVivo-class bioreactor positioning.
- **Coverage:** no raw data files were written for the requested 24-hour window. The nightly `searxng-fallback` slot for the 2026-09-22 window does not yet exist on disk at the time of this write (`~/.openwiki/connectors/web-search/raw/2026-09-21T18-35-04-searxng-fallback/` is the most recent fallback directory and it is empty; no 2026-09-22T fallback directory has been created) — so no fallback result either. The 2026-09-14 → 2026-09-21 fallback directories are all present but empty. No new source-backed evidence about CelVivo, 3Brain, Cellink, or organoid news was available.
+- **Nature, 2026-07-24:** [Engineering etiology-aligned in vitro models of human vessels](https://www.nature.com/articles/s41378-026-01397-9). 0.165 score. Disease-specific in vitro vessel models — organoid/3D-cell-culture adjacent.
- **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, `/personal-logistics.md`, or `/quickstart.md`. The skipped pull adds zero new evidence, so the `class-organoid-3d-bioprinting` / `MiniMax-m3` / `hermes-agent-v0-19-quicksilver` / `agent-memory-architecture` / `china-cde-cell-gene-therapy-rules-2026` / `china-order-no-818-clinical-translation` theme rows remain anchored on the 2026-08-03 Tavily baseline + post-2026-08-03 evidence from other sources, and the 8 Tavily-anchored commitment items (`china-cde-cell-gene-therapy-rules-2026`, `celvivo-clinoreactor-thewell-bioscience-xeno-free`, `china-order-no-818-clinical-translation`, `cellink-bio-x-gen3-customer-evidence`, `china-cgt-2026-july-developments`, `3brain-coreplate-2026-conference-positioning`, `celvivo-clinostar-2-nams-demo-2026`, `liang-2026-celvivo-clinostar-positioning`) all stay anchored on the 2026-07-26 → 2026-08-03 Tavily baseline.
+- **BioSpace, 2026-07-23:** [Roche showcases intelligent lab solutions and high-precision instruments at ADLM 2026](https://www.biospace.com/press-releases/roche-showcases-intelligent-lab-solutions-and-high-precision-instruments-at-adlm-2026-to-help-laboratories-address-workforce-and-workflow-challenges). 0.151 score. Industry context, not vendor-anchored to Robin's 4 lines.
 - **Operational note:** the connector's on-disk configuration and runtime registration remain inconsistent. Configure `TAVILY_API_KEY` in the OpenWiki runtime **and** refresh the connector registry before the next pull. This is the **fortieth consecutive skip** on the same code path (after 2026-08-08 + 2026-08-10 + 2026-08-12 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 + 2026-08-27 + 2026-08-28 + 2026-08-29 + 2026-08-30 + 2026-08-31 + 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 + 2026-09-10 + 2026-09-11 + 2026-09-12 + 2026-09-13 + 2026-09-14 + 2026-09-15 + 2026-09-16 + 2026-09-17 + 2026-09-18 + 2026-09-19 + 2026-09-20 + 2026-09-21); the latest successful Tavily pull remains 2026-08-03 18:08 UTC. The 40-day skip streak means the Tavily lane has not produced any new vendor-news evidence for CelVivo / 3Brain / Cellink / Femtobiomed / organoid workflows in the entire 2026-08-08 → 2026-09-22 window, which is the canonical source lane for those vendors (they have no material Hacker News footprint — see `/sources/hackernews.md` query-hit table); the operational blocker remains `TAVILY_API_KEY` provisioning + connector-registry refresh.
-## 2026-09-21 attempted update — skipped
+### Hermes Agent best-models eval — source-backed (workflow tooling, low priority)
- **Status:** skipped. The runtime reported that `web-search-1` was not enabled (`Set enabled=true in ~/.openwiki/connectors/web-search/config.json`) — the on-disk `~/.openwiki/connectors/web-search/config.json` actually does set `"enabled": true`, so the runtime's connector-registry view has drifted from the file on disk; the registry needs a refresh before the next pull. The deterministic pull result for this run matches the same condition: `Web Search connector is not enabled. Set enabled=true in ~/.openwiki/connectors/web-search/config.json.`
+- **haimaker.ai, 2026-07-23:** [Best Models for Hermes Agent (July 2026): Tested & Ranked](https://haimaker.ai/blog/best-models-for-hermes-agent). 0.731 score. Third-party ranking of LLMs for Hermes Agent usage — Robin-relevant as the daily-driver stack. Folds into the existing `MiniMax-m3` theme row last-seen.
- **Authentication:** `TAVILY_API_KEY` was not present in the runtime environment, so even an enabled connector would not have made a Tavily request. The source-specific instruction for this run explicitly notes the same condition (`needs TAVILY_API_KEY, currently empty`).
+- **Reddit, 2026-07-22:** [What are you USE CASES for Hermes Agent?](https://www.reddit.com/r/hermesagent/comments/1v34auv/what_are_you_use_cases_for_hermes_agent). 0.424 score. User-driven Hermes use cases; not a vendor-anchored signal.
- **Coverage:** no raw data files were written for the requested 24-hour window. The nightly `searxng-fallback` slot for the 2026-09-21 window does not yet exist on disk at the time of this write (`~/.openwiki/connectors/web-search/raw/2026-09-20T18-35-04-searxng-fallback/` is the most recent fallback directory and it is empty; no 2026-09-21T fallback directory has been created) — so no fallback result either. The 2026-09-14 → 2026-09-20 fallback directories are all present but empty. No new source-backed evidence about CelVivo, 3Brain, Cellink, or organoid news was available.
+- **Data-quality flag:** Tavily's synthesized *answer* for this lane hallucinated detail ("streaming robustness, REPL UX improvements, and provider hardening") — none of those bullets appear in the haimaker article. Treat Tavily's answer text as untrusted.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, `/personal-logistics.md`, or `/quickstart.md`. The skipped pull adds zero new evidence, so the `class-organoid-3d-bioprinting` / `MiniMax-m3` / `hermes-agent-v0-19-quicksilver` / `agent-memory-architecture` / `china-cde-cell-gene-therapy-rules-2026` / `china-order-no-818-clinical-translation` theme rows remain anchored on the 2026-08-03 Tavily baseline + post-2026-08-03 evidence from other sources, and the 8 Tavily-anchored commitment items (`china-cde-cell-gene-therapy-rules-2026`, `celvivo-clinoreactor-thewell-bioscience-xeno-free`, `china-order-no-818-clinical-translation`, `cellink-bio-x-gen3-customer-evidence`, `china-cgt-2026-july-developments`, `3brain-coreplate-2026-conference-positioning`, `celvivo-clinostar-2-nams-demo-2026`, `liang-2026-celvivo-clinostar-positioning`) all stay anchored on the 2026-07-26 → 2026-08-03 Tavily baseline.
 - **Operational note:** the connector's on-disk configuration and runtime registration remain inconsistent. Configure `TAVILY_API_KEY` in the OpenWiki runtime **and** refresh the connector registry before the next pull. This is the **thirty-ninth consecutive skip** on the same code path (after 2026-08-08 + 2026-08-10 + 2026-08-12 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 + 2026-08-27 + 2026-08-28 + 2026-08-29 + 2026-08-30 + 2026-08-31 + 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 + 2026-09-10 + 2026-09-11 + 2026-09-12 + 2026-09-13 + 2026-09-14 + 2026-09-15 + 2026-09-16 + 2026-09-17 + 2026-09-18 + 2026-09-19 + 2026-09-20); the latest successful Tavily pull remains 2026-08-03 18:08 UTC. The 39-day skip streak means the Tavily lane has not produced any new vendor-news evidence for CelVivo / 3Brain / Cellink / Femtobiomed / organoid workflows in the entire 2026-08-08 → 2026-09-21 window, which is the canonical source lane for those vendors (they have no material Hacker News footprint — see `/sources/hackernews.md` query-hit table); the operational blocker remains `TAVILY_API_KEY` provisioning + connector-registry refresh.
-## 2026-09-20 attempted update — skipped
+### CelVivo / 3Brain / Cellink / CellShot lanes — same Nature results, Tavily answer text mis-attributed
- **Status:** skipped. The runtime reported that `web-search-1` was not enabled (`Set enabled=true in ~/.openwiki/connectors/web-search/config.json`) — the on-disk `~/.openwiki/connectors/web-search/config.json` actually does set `"enabled": true`, so the runtime's connector-registry view has drifted from the file on disk; the registry needs a refresh before the next pull.
+- **CelVivo ClinoReactor / Cellink BIO X:** the Nature [MO:BOT liver-spheroid automation paper](https://www.nature.com/articles/s41598-026-58939-4) reappears at score 0.402 (CelVivo lane) and 0.074 (Cellink lane). Tavily's answer text describes MO:BOT but labels the platform "ClinoReactor" / "BIO X" — vendor attribution is **wrong**. Treat the result as the MO:BOT paper, not a CelVivo or Cellink product claim.
- **Authentication:** `TAVILY_API_KEY` was not present in the runtime environment, so even an enabled connector would not have made a Tavily request. The source-specific instruction for this run explicitly notes the same condition (`needs TAVILY_API_KEY, currently empty`).
+- **3Brain CorePlate MEA:** the Nature [portable semi-dry EEG device paper](https://www.nature.com/articles/s41598-026-52672-8) reappears at score 0.187. Tavily's answer text labels it "3Brain CorePlate MEA 2026" — this is wrong; the paper is about an EEG headset, not 3Brain's MEA chips. Do not promote as 3Brain evidence.
- **Coverage:** no raw data files were written for the requested 24-hour window. The nightly `searxng-fallback` slot for the 2026-09-20 window does not yet exist on disk at the time of this write (`~/.openwiki/connectors/web-search/raw/2026-09-19T18-35-03-searxng-fallback/` is the most recent fallback directory and it is empty; no 2026-09-20T fallback directory has been created) — so no fallback result either. The 2026-09-14 → 2026-09-19 fallback directories are all present but empty. No new source-backed evidence about CelVivo, 3Brain, Cellink, or organoid news was available.
+- **CellShot / CellPick:** Cellares–Papillon partnership (Cellares is unrelated to Femtobiomed) and CCDx liquid biopsy — no direct Femtobiomed result in either pull.
- **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, `/personal-logistics.md`, or `/quickstart.md`. The skipped pull adds zero new evidence, so the `class-organoid-3d-bioprinting` / `MiniMax-m3` / `hermes-agent-v0-19-quicksilver` / `agent-memory-architecture` / `china-cde-cell-gene-therapy-rules-2026` / `china-order-no-818-clinical-translation` theme rows remain anchored on the 2026-08-03 Tavily baseline + post-2026-08-03 evidence from other sources.
+- **CelVivo installed-base:** no direct result; pull dominated by Cepheid GeneXpert noise. Query phrasing needs a vendor-name anchor to retrieve CelVivo-specific results.
 - **Operational note:** the connector's on-disk configuration and runtime registration remain inconsistent. Configure `TAVILY_API_KEY` in the OpenWiki runtime **and** refresh the connector registry before the next pull. This is the **thirty-eighth consecutive skip** at the time of its attempt (thirty-ninth including the 2026-09-21 follow-up) on the same code path (after 2026-08-08 + 2026-08-10 + 2026-08-12 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 + 2026-08-27 + 2026-08-28 + 2026-08-29 + 2026-08-30 + 2026-08-31 + 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 + 2026-09-10 + 2026-09-11 + 2026-09-12 + 2026-09-13 + 2026-09-14 + 2026-09-15 + 2026-09-16 + 2026-09-17 + 2026-09-18 + 2026-09-19); the latest successful Tavily pull remains 2026-08-03 18:08 UTC. The 2026-09-21 follow-up attempt landed as the **thirty-ninth consecutive skip**.
-## 2026-09-19 attempted update — skipped
+### OpenWiki / RAGFlow / agent-memory-wiki lanes — Tavily recall broken
- **Status:** skipped. The runtime reported that `web-search-1` was not enabled (`Set enabled=true in ~/.openwiki/connectors/web-search/config.json`) — the on-disk `~/.openwiki/connectors/web-search/config.json` actually does set `"enabled": true`, so the runtime's connector-registry view has drifted from the file on disk; the registry needs a refresh before the next pull.
+- "OpenWiki connectors Tavily RAGFlow 2026" returned SmartBall X pipeline inspection, AWWA ACE26, insurance backchat, helicopter partnership, OLED manufacturing equipment, and fashion-show slides. None of the 8 results touches Robin's actual stack (OpenWiki / Gitea / Wiki.js / RAGFlow / NocoDB / SeaFile). Skip until the query is rephrased.
- **Authentication:** `TAVILY_API_KEY` was not present in the runtime environment, so even an enabled connector would not have made a Tavily request. The source-specific instruction for this run explicitly notes the same condition (`needs TAVILY_API_KEY, currently empty`).
+- "Agent personal memory wiki 2026" returned an Australian enterprise data-AI survey (0.403), a LangChain4j self-building-agent experiment (0.168), and ad-agency awards — no direct personal-wiki / OpenWiki-self evidence. Adjacent only.
 - **Coverage:** no raw data files were written for the requested 24-hour window. The nightly `searxng-fallback` slot for the 2026-09-19 window does not yet exist on disk at the time of this write (`~/.openwiki/connectors/web-search/raw/2026-09-18T18-35-04-searxng-fallback/` is the most recent fallback directory and it is empty; no 2026-09-19T fallback directory has been created) — so no fallback result either. The 2026-09-14 → 2026-09-18 fallback directories are all present but empty. No new source-backed evidence about CelVivo, 3Brain, Cellink, or organoid news was available.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, `/personal-logistics.md`, or `/quickstart.md`. The skipped pull adds zero new evidence, so the `class-organoid-3d-bioprinting` / `MiniMax-m3` / `hermes-agent-v0-19-quicksilver` / `agent-memory-architecture` / `china-cde-cell-gene-therapy-rules-2026` / `china-order-no-818-clinical-translation` theme rows remain anchored on the 2026-08-03 Tavily baseline + post-2026-08-03 evidence from other sources.
 - **Operational note:** the connector's on-disk configuration and runtime registration remain inconsistent. Configure `TAVILY_API_KEY` in the OpenWiki runtime **and** refresh the connector registry before the next pull. This is the **thirty-seventh consecutive skip** on the same code path (after 2026-08-08 + 2026-08-10 + 2026-08-12 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 + 2026-08-27 + 2026-08-28 + 2026-08-29 + 2026-08-30 + 2026-08-31 + 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 + 2026-09-10 + 2026-09-11 + 2026-09-12 + 2026-09-13 + 2026-09-14 + 2026-09-15 + 2026-09-16 + 2026-09-17 + 2026-09-18); the latest successful Tavily pull remains 2026-08-03 18:08 UTC. The 37-day skip streak means the Tavily lane has not produced any new vendor-news evidence for CelVivo / 3Brain / Cellink / Femtobiomed / organoid workflows in the entire 2026-08-08 → 2026-09-19 window, which is the canonical source lane for those vendors (they have no material Hacker News footprint — see `/sources/hackernews.md` query-hit table); the operational blocker is `TAVILY_API_KEY` provisioning + connector-registry refresh.
-## 2026-09-18 attempted update — skipped
+## Source coverage (cumulative)
- **Status:** skipped. The runtime reported that `web-search-1` was not enabled (`Set enabled=true in ~/.openwiki/connectors/web-search/config.json`) — the on-disk `~/.openwiki/connectors/web-search/config.json` actually does set `"enabled": true`, so the runtime's connector-registry view has drifted from the file on disk; the registry needs a refresh before the next pull.
+- Pull 1: fetched 2026-07-26T17:39:11Z — raw `~/.openwiki/connectors/web-search/raw/2026-07-26T17-38-33-286Z/web-search-results.json`
- **Authentication:** `TAVILY_API_KEY` was not present in the runtime environment, so even an enabled connector would not have made a Tavily request. The source-specific instruction for this run explicitly notes the same condition (`needs TAVILY_API_KEY, currently empty`).
+- Pull 2: fetched 2026-07-26T18:07:27Z — raw `~/.openwiki/connectors/web-search/raw/2026-07-26T18-07-14-335Z/web-search-results.json`
- **Coverage:** no raw data files were written for the requested 24-hour window. The nightly `searxng-fallback` slot for the 2026-09-18 window does not yet exist on disk at the time of this write (`~/.openwiki/connectors/web-search/raw/2026-09-17T18-35-06-searxng-fallback/` is the most recent fallback directory and it is empty; no 2026-09-18T fallback directory has been created) — so no fallback result either. The 2026-09-14 → 2026-09-17 fallback directories are all present but empty. No new source-backed evidence about CelVivo, 3Brain, Cellink, or organoid news was available.
+- Pull 3: fetched 2026-07-26T18:16:21Z — raw `~/.openwiki/connectors/web-search/raw/2026-07-26T18-16-06-804Z/web-search-results.json`
- **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, `/personal-logistics.md`, or `/quickstart.md`. The skipped pull adds zero new evidence, so the `class-organoid-3d-bioprinting` / `MiniMax-m3` / `hermes-agent-v0-19-quicksilver` / `agent-memory-architecture` / `china-cde-cell-gene-therapy-rules-2026` / `china-order-no-818-clinical-translation` theme rows remain anchored on the 2026-08-03 Tavily baseline + post-2026-08-03 evidence from other sources.
+- Queries: pull 1 + pull 2 = 10 queries each; pull 3 = 6 queries (vendor-anchored only)
- **Operational note:** the connector's on-disk configuration and runtime registration remain inconsistent. Configure `TAVILY_API_KEY` in the OpenWiki runtime **and** refresh the connector registry before the next pull. This is the **thirty-sixth consecutive skip** at the time of its attempt (thirty-seventh including the 2026-09-19 follow-up) on the same code path (after 2026-08-08 + 2026-08-10 + 2026-08-12 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 + 2026-08-27 + 2026-08-28 + 2026-08-29 + 2026-08-30 + 2026-08-31 + 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 + 2026-09-10 + 2026-09-11 + 2026-09-12 + 2026-09-13 + 2026-09-14 + 2026-09-15 + 2026-09-16 + 2026-09-17); the latest successful Tavily pull remains 2026-08-03 18:08 UTC. The 36-day skip streak means the Tavily lane has not produced any new vendor-news evidence for CelVivo / 3Brain / Cellink / Femtobiomed / organoid workflows in the entire 2026-08-08 → 2026-09-18 window, which is the canonical source lane for those vendors (they have no material Hacker News footprint — see `/sources/hackernews.md` query-hit table); the operational blocker is `TAVILY_API_KEY` provisioning + connector-registry refresh. The 2026-09-19 follow-up attempt landed as the **thirty-seventh consecutive skip**.
+- Instance: `web-search-1`
-## 2026-09-17 attempted update — skipped
+---
- **Status:** skipped. The runtime reported that `web-search-1` was not enabled (`Set enabled=true in ~/.openwiki/connectors/web-search/config.json`) — the on-disk `~/.openwiki/connectors/web-search/config.json` actually does set `"enabled": true`, so the runtime's connector-registry view has drifted from the file on disk; the registry needs a refresh before the next pull.
+## 2026-07-26 18:16 pull
 - **Authentication:** `TAVILY_API_KEY` was not present in the runtime environment, so even an enabled connector would not have made a Tavily request.
 - **Coverage:** no raw data files were written for the requested 24-hour window. The nightly `searxng-fallback` slot for the 2026-09-17T18:35 window does not exist on disk at all (`~/.openwiki/connectors/web-search/raw/2026-09-16T18-35-03-searxng-fallback/` is the most recent fallback directory and it is empty; no 2026-09-17T fallback directory has been created) — so no fallback result either. No new source-backed evidence about CelVivo, 3Brain, Cellink, or organoid news was available.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, `/personal-logistics.md`, or `/quickstart.md`. The skipped pull adds zero new evidence, so the `class-organoid-3d-bioprinting` / `MiniMax-m3` / `hermes-agent-v0-19-quicksilver` / `agent-memory-architecture` / `china-cde-cell-gene-therapy-rules-2026` / `china-order-no-818-clinical-translation` theme rows remain anchored on the 2026-08-03 Tavily baseline + post-2026-08-03 evidence from other sources.
 - **Operational note:** the connector's on-disk configuration and runtime registration remain inconsistent. Configure `TAVILY_API_KEY` in the OpenWiki runtime **and** refresh the connector registry before the next pull. This is the **thirty-fifth consecutive skip** at the time of its attempt (thirty-sixth including the 2026-09-18 follow-up) on the same code path (after 2026-08-08 + 2026-08-10 + 2026-08-12 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 + 2026-08-27 + 2026-08-28 + 2026-08-29 + 2026-08-30 + 2026-08-31 + 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 + 2026-09-10 + 2026-09-11 + 2026-09-12 + 2026-09-13 + 2026-09-14 + 2026-09-15 + 2026-09-16); the latest successful Tavily pull remains 2026-08-03 18:08 UTC. The 35-day skip streak means the Tavily lane has not produced any new vendor-news evidence for CelVivo / 3Brain / Cellink / Femtobiomed / organoid workflows in the entire 2026-08-08 → 2026-09-17 window, which is the canonical source lane for those vendors (they have no material Hacker News footprint — see `/sources/hackernews.md` query-hit table); the operational blocker is `TAVILY_API_KEY` provisioning + connector-registry refresh.
-## 2026-09-16 attempted update — skipped
+Third Tavily pull on the same day, after the 2026-07-27 `~/.openwiki/INSTRUCTIONS.md` scope was loaded. The query lane was narrowed from 10 vendor-mixed queries to **6 vendor-anchored queries**, dropping the China-cell-therapy regulation lane (now stale-pinned via `/commitments.md`), the Hermes Agent / MiniMax M3 daily-driver lane, and the OpenWiki/RAGFlow/agent-memory lanes (the latter two were already noise per the prior pulls).
- **Status:** skipped. The runtime reported that `web-search-1` was not enabled (`Set enabled=true in ~/.openwiki/connectors/web-search/config.json`).
+### Queries and top results
 - **Authentication:** `TAVILY_API_KEY` was not present, so no Tavily request was made.
 - **Coverage:** no raw data files were written for the requested 24-hour window. The nightly searxng-fallback slot for the 24-hour window is also empty on disk (no fallback result) — no web-search evidence of any kind landed in the window. No new source-backed evidence about CelVivo, 3Brain, Cellink, or organoid news was available.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md`.
 - **Operational note:** the connector's on-disk configuration and runtime registration remain inconsistent. Configure `TAVILY_API_KEY` in the OpenWiki runtime and refresh the connector registry before the next pull. This is the **thirty-fourth consecutive skip** at the time of its attempt (thirty-sixth including the 2026-09-17 + 2026-09-18 follow-ups) on the same code path (after 2026-08-08 + 2026-08-10 + 2026-08-12 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 + 2026-08-27 + 2026-08-28 + 2026-08-29 + 2026-08-30 + 2026-08-31 + 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 + 2026-09-10 + 2026-09-11 + 2026-09-12 + 2026-09-13 + 2026-09-14 + 2026-09-15); the latest successful Tavily pull remains 2026-08-03 18:08 UTC. The 2026-09-17 follow-up attempt landed as the **thirty-fifth consecutive skip**; the 2026-09-18 follow-up attempt landed as the **thirty-sixth consecutive skip**.
-## 2026-09-15 attempted update — skipped
+| Query | Top hits | Score | Vendor-anchor |
 | --- | --- | --- | --- |
 | `CelVivo ClinoReactor spheroid new paper 2026` | Nature MO:BOT liver-spheroid automation paper (re-mention); Patient-Derived Tumor Organoids for personalizing cancer treatment; CCDx whole-cell genomic profiling | 0.44 / 0.11 / 0.05 | no — MO:BOT, not CelVivo; organoid application only |
 | `3Brain CorePlate MEA neuron 2026` | News-Medical.net "New imaging platform tracks hundreds of neurons at unprecedented depths"; BioSpace brain-remodeling-during-adolescence; MobiHealthNews first able-bodied BCI recipients | 0.20 / 0.10 / 0.08 | no — generic neuroscience imaging, not 3Brain CorePlate |
 | `Cellink BIO X bioprinter clinical 2026` | Roche ADLM 2026 intelligent lab solutions; 10x Genomics CLIA lab + Cleveland Clinic; Massive Bio FOMAT cancer prescreening | 0.11 / 0.09 / 0.07 | no — industry context; 10x / Massive Bio unrelated to Cellink |
 | `organoid-on-chip pharmacology 2026` | AcroCyte Therapeutics ARPA-H funding for scalable human-organoid tech (re-mention, score up to 0.617 from 0.215); Patient-Derived Tumor Organoids; Nature MO:BOT liver-spheroid | 0.62 / 0.41 / 0.35 | no — AcroCyte is application, not one of Robin's 4 vendors |
 | `CellShot CellPick bioprinter research 2026` | Cellares–Papillon PPL-001 automation partnership (re-mention); CCDx whole-cell genomic profiling; Genetic Engineering AI protein-engineering for biomanufacturing | 0.17 / 0.14 / 0.08 | no — Cellares/Papillon unrelated to Femtobiomed |
 | `lab automation assay workflow news 2026` | Roche ADLM 2026; Nature MO:BOT liver-spheroid; Cepheid third-generation GeneXpert at ADLM 2026 | 0.82 / 0.74 / 0.56 | no — Roche/Cepheid industry context, not vendor-anchored |
- **Status:** skipped. The runtime reported that `web-search-1` was not enabled (`Set enabled=true in ~/.openwiki/connectors/web-search/config.json`).
+### Synthesis result
 - **Authentication:** `TAVILY_API_KEY` was not present, so no Tavily request was made.
 - **Coverage:** no raw data files were written for the requested 24-hour window. The nightly searxng-fallback slot for the 24-hour window is also empty on disk (no fallback result) — no web-search evidence of any kind landed in the window. No new source-backed evidence about CelVivo, 3Brain, Cellink, or organoid news was available.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md`.
 - **Operational note:** the connector's on-disk configuration and runtime registration remain inconsistent. Configure `TAVILY_API_KEY` in the OpenWiki runtime and refresh the connector registry before the next pull. This is the **thirty-third consecutive skip** on the same code path (after 2026-08-08 + 2026-08-10 + 2026-08-12 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 + 2026-08-27 + 2026-08-28 + 2026-08-29 + 2026-08-30 + 2026-08-31 + 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 + 2026-09-10 + 2026-09-11 + 2026-09-12 + 2026-09-13 + 2026-09-14); the latest successful Tavily pull remains 2026-08-03 18:08 UTC. The 2026-09-16 follow-up attempt landed as the **thirty-fourth consecutive skip**; recast the 2026-09-15 attempt as the **thirty-third** at the time of its attempt (thirty-fourth including the 2026-09-16 follow-up).
-## 2026-09-14 attempted update — skipped
+- **No new vendor-anchored evidence** — every query's top hit is either (a) application/organoid-level without naming Robin's 4 vendors, (b) a re-mention of an item already in the 17:38 or 18:07 pull, or (c) an unrelated industry/competitor brand (Roche, Cepheid, 10x, Cellares, Massive Bio, CCDx).
 - **AcroCyte ARPA-H** reappears at 0.617 (up from 0.215 in the 18:07 pull). Same item, stronger score — the existing `/themes.md` `class-organoid-3d-bioprinting` row already covers it via the ARPA-H funding evidence; no new row needed.
 - **Tavily answer-text vendor mis-attribution continues.** The `CelVivo ClinoReactor spheroid new paper 2026` answer text describes MO:BOT but labels it "ClinoReactor"; the `3Brain CorePlate MEA neuron 2026` answer text points at generic brain-imaging news without anchoring to CorePlate. Treat Tavily answer text as untrusted and only the underlying URLs as evidence.
 - **Dropped lanes** (vs. pull 2): `China cell therapy 3D bioprinting regulation 2026` (China CDE item still anchored in `/commitments.md` as `china-cde-cell-gene-therapy-rules-2026`); `Hermes Agent MiniMax M3 changelog 2026` (already in `/themes.md` `MiniMax-m3` row); `OpenWiki connectors Tavily RAGFlow 2026` (noise); `agent personal memory wiki 2026` (noise). Existing rows on `/themes.md` and `/commitments.md` are unchanged because their evidence sources (Tavily pull 2, HN pull 18:00) are still on disk and referenceable.
- **Status:** skipped. The runtime reported that `web-search-1` was not enabled (`Set enabled=true in ~/.openwiki/connectors/web-search/config.json`).
+### Coverage note for next update
 - **Authentication:** `TAVILY_API_KEY` was not present, so no Tavily request was made.
 - **Coverage:** no raw data files were written for the requested 24-hour window. The nightly searxng-fallback slot for the 24-hour window is also empty on disk (no fallback result) — no web-search evidence of any kind landed in the window. No new source-backed evidence about CelVivo, 3Brain, Cellink, or organoid news was available.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md`.
 - **Operational note:** the connector's on-disk configuration and runtime registration remain inconsistent. Configure `TAVILY_API_KEY` in the OpenWiki runtime and refresh the connector registry before the next pull. This is the **thirty-second consecutive skip** on the same code path (after 2026-08-08 + 2026-08-10 + 2026-08-12 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 + 2026-08-27 + 2026-08-28 + 2026-08-29 + 2026-08-30 + 2026-08-31 + 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 + 2026-09-10 + 2026-09-11 + 2026-09-12 + 2026-09-13); the latest successful Tavily pull remains 2026-08-03 18:08 UTC. The 2026-09-15 + 2026-09-16 follow-up attempts landed as the **thirty-third + thirty-fourth consecutive skips**; recast the 2026-09-14 attempt as the **thirty-second** at the time of its attempt (thirty-fourth including the 2026-09-15 + 2026-09-16 follow-ups).
-## 2026-09-13 attempted update — skipped
+The China CDE regulatory lane is no longer being refreshed on every Tavily pull. The existing `/commitments.md` item pins it as `source-backed` with one credible cisema.com source. If a future Tavily or HN pull surfaces an NMPA / CDE-direct corroboration, promote from watchlist to `source-backed` and move into `/themes.md` as a confirmed row.
 ll
- **Status:** skipped. The runtime reported that `web-search-1` was not enabled (`Set enabled=true in ~/.openwiki/connectors/web-search/config.json`).
+Fourth Tavily pull on the 2026-07-27 cycle, run as a stand-alone `openwiki personal --update` source ingest. All 10 queries were re-run. Two lanes produced genuinely new material evidence (CelVivo / ClinoReactor vendor-anchored signal; Hermes Agent v0.19 Quicksilver workflow-tooling release). One lane (3D-bioprinted-organoid reviews) added supporting evidence to the existing `class-organoid-3d-bioprinting` row. The Tavily answer-text mis-attribution pattern recurred on the 3Brain, Cellink, and MiniMax-M3 lanes — flagged again below.
 - **Authentication:** `TAVILY_API_KEY` was not present, so no Tavily request was made.
 - **Coverage:** no raw data files were written for the requested 24-hour window. The nightly searxng-fallback slot for the 24-hour window is also empty on disk (no fallback result) — no web-search evidence of any kind landed in the window. No new source-backed evidence about CelVivo, 3Brain, Cellink, or organoid news was available.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md`.
 - **Operational note:** the connector's on-disk configuration and runtime registration remain inconsistent. Configure `TAVILY_API_KEY` in the OpenWiki runtime and refresh the connector registry before the next pull. This is the **thirty-first consecutive skip** on the same code path (after 2026-08-08 + 2026-08-10 + 2026-08-12 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 + 2026-08-27 + 2026-08-28 + 2026-08-29 + 2026-08-30 + 2026-08-31 + 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 + 2026-09-10 + 2026-09-11 + 2026-09-12); the latest successful Tavily pull remains 2026-08-03 18:08 UTC. The 2026-09-14 + 2026-09-15 + 2026-09-16 follow-up attempts landed as the **thirty-second + thirty-third + thirty-fourth consecutive skips**; recast the 2026-09-13 attempt as the **thirty-first** at the time of its attempt (thirty-fourth including the 2026-09-14 + 2026-09-15 + 2026-09-16 follow-ups).
-## 2026-09-12 attempted update — skipped
+### CelVivo ClinoReactor + TheWell Bioscience xeno-free workflow — source-backed
- **Status:** skipped. The runtime reported that `web-search-1` was not enabled (`Set enabled=true in ~/.openwiki/connectors/web-search/config.json`).
+This is the **first vendor-anchored CelVivo signal in any Tavily pull**. Prior pulls returned only MO:BOT or generic organoid content. Three TheWell Bioscience pages published in the 2026-07-21 / 2026-07-23 / 2026-07-25 window all reference "CelVivo ClinoReactor™" by name in their product content:
 - **Authentication:** `TAVILY_API_KEY` was not present, so no Tavily request was made.
 - **Coverage:** no raw data files were written for the requested 24-hour window. The nightly searxng-fallback slot for the 24-hour window is also empty on disk (no fallback result) — no web-search evidence of any kind landed in the window. No new source-backed evidence about CelVivo, 3Brain, Cellink, or organoid news was available.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md`.
 - **Operational note:** the connector's on-disk configuration and runtime registration remain inconsistent. Configure `TAVILY_API_KEY` in the OpenWiki runtime and refresh the connector registry before the next pull. This is the **thirtieth consecutive skip** on the same code path (after 2026-08-08 + 2026-08-10 + 2026-08-12 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 + 2026-08-27 + 2026-08-28 + 2026-08-29 + 2026-08-30 + 2026-08-31 + 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 + 2026-09-10 + 2026-09-11); the latest successful Tavily pull remains 2026-08-03 18:08 UTC. The 2026-09-13 follow-up attempt landed as the **thirty-first consecutive skip**; recast the 2026-09-12 attempt as the **thirtieth** at the time of its attempt (thirty-first including the 2026-09-13 follow-up).
-## 2026-09-11 attempted update — skipped
+- **TheWell Bioscience, 2026-07-21:** [Cell Culture Media (Xeno-Free)](https://www.thewellbio.com/product-category/xeno-free-cell-culture-media). Score 0.591. "An all-in-one xeno-free kit with optimized matrix, medium, and reagents … 3D neural stem cell culture. 2026 TheWell Bioscience Inc. CelVivo ClinoReactorTM". Position: ClinoReactor as the vessel in a complete xeno-free workflow.
 - **TheWell Bioscience, 2026-07-25:** [Xeno-Free Stem Cell Culture Product Guide](https://www.thewellbio.com/xeno-free-stem-cell-culture-guide). Score 0.585. Comprehensive product guide featuring validated applications and optimized workflows that name ClinoReactorTM as part of the integrated workflow.
 - **TheWell Bioscience, 2026-07-23:** [White Paper — Culture Apical-Out Organoids with Xeno-Free VitroGel System](https://www.thewellbio.com/white-paper_culture-apical-out-organoids-with-xeno-free-vitrogel-system). Score 0.213. "3D Cell Culture Scale-up by Using VitroGel® Hydrogel Matrix embedding in CelVivo ClinoReactorTM" — directly frames ClinoReactor as the scale-up vessel for apical-out organoids.
 - **TheWell Bioscience, 2026-07-21:** [Culture Apical-Out Organoids with Xeno-Free VitroGel® System (on-demand webinar)](https://www.thewellbio.com/white-papers/culture-apical-out-organoids-with-xeno-free-with-vitrogel). Score 0.179. Companion webinar to the white paper.
- **Status:** skipped. The runtime reported that `web-search-1` was not enabled (`Set enabled=true in ~/.openwiki/connectors/web-search/config.json`).
+**Tavily answer-text quality is honest on this lane** — the response correctly names TheWell Bioscience's xeno-free product and references ClinoReactor, not hallucinated vendor attributions.
 - **Authentication:** `TAVILY_API_KEY` was not present, so no Tavily request was made.
 - **Coverage:** no raw data files were written for the requested 24-hour window. The nightly searxng-fallback slot for the 24-hour window is also empty on disk (no fallback result) — no web-search evidence of any kind landed in the window. No new source-backed evidence about CelVivo, 3Brain, Cellink, or organoid news was available.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md`.
 - **Operational note:** the connector's on-disk configuration and runtime registration remain inconsistent. Configure `TAVILY_API_KEY` in the OpenWiki runtime and refresh the connector registry before the next pull. This is the **twenty-ninth consecutive skip** on the same code path (after 2026-08-08 + 2026-08-10 + 2026-08-12 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 + 2026-08-27 + 2026-08-28 + 2026-08-29 + 2026-08-30 + 2026-08-31 + 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 + 2026-09-10); the latest successful Tavily pull remains 2026-08-03 18:08 UTC.
-## 2026-09-10 attempted update — skipped
+**Robin relevance:** high. This is the only Tavily pull where CelVivo ClinoReactor has been named by a vendor-adjacent (media/reagent) partner, with three same-week pages and a white paper. Possible interpretations: (a) CelVivo-TheWell co-marketing agreement; (b) TheWell is using ClinoReactor as a reference platform for their own product positioning; (c) organic partner content. Promoted to `/commitments.md` as `celvivo-clinoreactor-thewell-bioscience-xeno-free` with status "verify on next CelVivo vendor check". The new evidence is also folded into the `class-organoid-3d-bioprinting` row.
- **Status:** skipped. The runtime reported that `web-search-1` was not enabled (`Set enabled=true in ~/.openwiki/connectors/web-search/config.json`).
+### Hermes Agent v0.19 "Quicksilver" Release — source-backed (workflow tooling, low priority)
 - **Authentication:** `TAVILY_API_KEY` was not present, so no Tavily request was made.
 - **Coverage:** no raw data files were written for the requested 24-hour window. The nightly searxng-fallback slot for the 24-hour window is also empty on disk (no fallback result) — no web-search evidence of any kind landed in the window. No new source-backed evidence about CelVivo, 3Brain, Cellink, or organoid news was available.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md`.
 - **Operational note:** the connector's on-disk configuration and runtime registration remain inconsistent. Configure `TAVILY_API_KEY` in the OpenWiki runtime and refresh the connector registry before the next pull. The 2026-09-10 attempt was the **twenty-eighth consecutive skip** at the time of its attempt (twenty-ninth including the 2026-09-11 follow-up); the latest successful Tavily pull remains 2026-08-03 18:08 UTC.
-## 2026-09-09 attempted update — skipped
+The `Hermes Agent MiniMax M3 changelog 2026` query returned a material release note for **Hermes Agent v0.19**, the "Quicksilver" release from Nous Research. Note: Tavily's answer text hallucinated attribution to "MiniMax M3" (the underlying subject is Hermes Agent, not the M3 model). The underlying URLs confirm the release:
- **Status:** skipped. The runtime reported that `web-search-1` was not enabled.
+- **Instagram (techkwon reel), no exact date in 2026-07:** [Hermes Agent 0.19 Quicksilver Release notes](https://www.instagram.com/reel/DbB2yomkss8). Score 0.573. Names the v0.19 features: first-token delay 4.3s → 0.9s, profile routing, live subagent, delivery ledger, 1Password/Bitwarden integration.
- **Authentication:** `TAVILY_API_KEY` was not present, so no Tavily request was made.
+- **Instagram (Nous Research reel), 2026-07-25:** [Hermes Agent v0.19 Quicksilver Release](https://www.instagram.com/reel/DbGaGsoqUUx). Score 0.475. Nous Research's own channel describes the first-token-delay fix and the wider v0.19 feature set.
- **Coverage:** no raw data files were written for the requested 24-hour window. No new source-backed evidence about CelVivo, 3Brain, Cellink, or organoid news was available.
+- **Reddit r/hermesagent, 2026-07-22:** [What are your USE CASES for Hermes Agent?](https://www.reddit.com/r/hermesagent/comments/1v34auv/what_are_you_use_cases_for_hermes_agent). Score 0.424. 83 upvotes / 113 comments — community discussion of Hermes Agent usage patterns.
- **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md`.
+- **regolo.ai, 2026-07-27:** [TencentDB Agent Memory: Hermes & OpenClaw Setup Guide](https://regolo.ai/tencentdb-agent-memory-the-complete-guide-to-persistent-memory-for-hermes-and-openclaw-with-zero-data-retention). Score 0.120. Third-party persistent-memory backend for Hermes Agent — adjacent integration signal, not a Nous release item.
 - **Operational note:** the connector's on-disk configuration and runtime registration remain inconsistent. Configure `TAVILY_API_KEY` in the OpenWiki runtime and refresh the connector registry before the next pull. The 2026-09-09 attempt was the **twenty-seventh consecutive skip** at the time of its attempt (twenty-ninth including the 2026-09-10 + 2026-09-11 follow-ups); the latest successful Tavily pull remains 2026-08-03 18:08 UTC.
-## Prior coverage
+**Robin relevance:** Hermes Agent is Robin's daily-driver stack per `~/.openwiki/INSTRUCTIONS.md`. v0.19's profile routing, live subagent, and 1Password/Bitwarden integration are story-worthy shifts. New theme row `hermes-agent-v0-19-quicksilver` added to `/themes.md`; this is distinct from the existing `MiniMax-m3` row, which is about the M3 model itself.
-The 2026-09-08 and earlier recent update attempts were also skipped because the connector was unavailable or `TAVILY_API_KEY` was absent. No newer successful Tavily pull supersedes the 2026-08-03 evidence baseline. Pre-2026-08-03 successful Tavily pulls (e.g. 2026-07-26 → 2026-08-03) are summarized in the `/themes.md` Evidence cells for the relevant rows (`class-organoid-3d-bioprinting`, `china-cde-cell-gene-therapy-rules-2026`, `china-order-no-818-clinical-translation`, `hermes-agent-v0-19-quicksilver`, `agent-memory-architecture`, `MiniMax-m3`) and the deeper historical pull records lived in earlier iterations of this file before the 2026-09-09 / 2026-09-10 simplify pass. The historical 2026-07-27 / 2026-07-29 / 2026-07-30 / 2026-08-03 pull records are no longer detailed in this file; treat the Evidence-cell references as the canonical pointers to those pulls and reach for the underlying `~/.openwiki/connectors/web-search/raw/2026-08-03T18-08-*` manifest if a deeper audit is needed.
+**MCP 2026-07-28 revision finalization (adjacent watchlist):** [The Register, 2026-07-23](https://www.theregister.com/devops/2026/07/23/model-context-protocol-prepares-to-break-with-its-stateful-past/5276722) — score 0.059. MCP maintainers plan to finalize the 2026-07-28 protocol revision, not backward-compatible, breaks with stateful past. Single-source, low Tavily score, but directly relevant to OpenWiki's MCP server architecture. Folded into the new `hermes-agent-v0-19-quicksilver` theme row's Evidence column rather than spawning a separate row.
-` manifest if a deeper audit is needed.
+
 ### 3D bioprinted organoid reviews + Pluristyx hepatocyte manufacturing — folded into `class-organoid-3d-bioprinting`
 Two same-week review papers and one iPSC + aerospace clinical-grade hepatocyte manufacturing press release re-anchor the existing application-domain theme row:
 - **Oxford Academic, 2026-07-27:** [Three-dimensional bioprinted organoids: advances and applications](https://academic.oup.com/rb/article/8722305). Score 0.107. Review of bioprinting techniques, bio-ink development, and clinical applications. Application-domain evidence, not vendor-anchored.
 - **Sage journals, 2026-07-22:** [Three-Dimensional Bioprinting-Enabled Organoids](https://journals.sagepub.com/doi/10.1177/19373368261469463). Score 0.125. Review of major 3D bioprinting technologies (extrusion, droplet, photopolymerization). Application-domain evidence.
 - **GlobeNewswire via Manila Times, 2026-07-27:** [Pluristyx Partners With Leading Regenerative Medicine and Aerospace Pioneers to Standardize Clinical-Grade Hepatocyte Manufacturing for Space and Earth Applications](https://www.manilatimes.net/2026/07/27/tmt-newswire/globenewswire/pluristyx-partners-with-leading-regenerative-medicine-and-aerospace-pioneers-to-standardize-clinical-grade-hepatocyte-manufacturing-for-space-and-earth-applications/2392136). Score 0.219. Pluristyx (iPSC + genetically engineered solutions) partnering with aerospace players on clinical-grade hepatocyte manufacturing. Adjacent to ClinoReactor liver-spheroid use cases.
 All three items fold into the existing `class-organoid-3d-bioprinting` row. Last seen refreshed to 2026-07-27; evidence count increased.
 ### 3Brain / Cellink / CellShot / installed-base / RAGFlow lanes — no new vendor-anchored evidence; Tavily answer-text mis-attribution recurs
 - **3Brain CorePlate MEA 2026:** the Nature [portable semi-dry EEG device paper](https://www.nature.com/articles/s41598-026-52672-8) reappears at score 0.187. Tavily's answer text again labels it "3Brain CorePlate MEA 2026" validated in a brain-computer-interface study — the underlying paper is about a portable EEG headset, **not 3Brain MEA chips**. Do not promote as 3Brain evidence. Other hits in this lane (News-Medical FlatMux imaging, Precision Neuro BCI, BioTechniques bi-weekly) are application-domain only.
 - **Cellink BIO X bioprinter 2026:** no direct Cellink result. Top hits are Velo3D Livermore campus, Lumafield Mars X-ray inspection, AI protein engineering model, Repligen–BioLife ($1.5bn cell-therapy acquisition). All unrelated to Cellink BIO X / BIONOVA X / Lumen X. Application-domain only.
 - **CellShot / CellPick bioprinter 2026:** no Femtobiomed result. Cellares–Papillon PPL-001 partnership (Cellares is unrelated to Femtobiomed) at score 0.201, CCDx whole-cell genomic profiling at 0.164, Nature MO:BOT paper re-mention at 0.074. Tavily answer text honestly says "The CellShot CellPick bioprinter 2026 is not directly mentioned in the provided data sources."
 - **labs CelVivo ClinoStar installed base 2026:** no direct result. Cepheid GeneXpert third-generation ADLM 2026 (score 0.112) dominates the top slot and is unrelated to CelVivo installed-base. Query phrasing continues to drift toward competitor/molecular-diagnostic content.
 - **China cell therapy 3D bioprinting regulation 2026:** re-anchors the existing `/commitments.md` `china-cde-cell-gene-therapy-rules-2026` item. Top result: Roots Analysis [Cell Therapy Manufacturing Market Size 2035](https://www.rootsanalysis.com/reports/cell-therapy-manufacturing/285.html) (0.669) re-mentioning Merck's $11.3B Bio-Techne acquisition. Second hit: cisema.com (0.666) — the same China CDE source as the 2026-07-26 18:07 pull.
 - **OpenWiki connectors Tavily RAGFlow 2026:** Tavily recall still broken. Returns AWWA ACE26 SmartBall X pipeline inspection, MBT cybersecurity coverage, Seatrade S-100, OpenTug agricultural shipping, iVeena FDA meeting, RightShip–NorthStandard, LEO satellite scaling, Tokyo fashion show. None of the 8 results touches Robin's actual stack.
 - **agent personal memory wiki 2026:** iTnews State of Data & AI 2026 (Australian enterprise agentic AI, 0.403), LangChain4j self-building-agent (0.168), Times of Israel Cursor CVE-2026-48124 (0.121), Ad Age small-agency awards (0.103 / 0.103 / 0.083 / 0.082), MCP 2026-07-28 revision (0.059, see above). Only the MCP item is actionable; the rest is noise or adjacent to Robin's stack without direct relevance.
 ### Synthesis result
 - **Two new scope-aligned findings:** (a) CelVivo ClinoReactor + TheWell Bioscience xeno-free workflow (vendor-anchored, first time in any Tavily pull); (b) Hermes Agent v0.19 Quicksilver (workflow tooling, source-backed).
 - **Two supporting application-domain items** folded into the existing `class-organoid-3d-bioprinting` row: two 3D-bioprinted organoid review papers (Oxford 2026-07-27, Sage 2026-07-22) and Pluristyx iPSC + aerospace hepatocyte manufacturing press release (2026-07-27).
 - **Tavily answer-text mis-attribution pattern persists** on the 3Brain and Cellink lanes; this is the third pull in a row where the answer text names a vendor that is not actually in the underlying source. Continue treating Tavily answer text as untrusted; only the underlying URLs are evidence.
 - **OpenWiki / RAGFlow lane** still produces zero relevant results after four pulls. Consider dropping this lane from future Tavily runs unless the query is rephrased to anchor on product names (e.g. "RAGFlow 0.x release notes" instead of "OpenWiki connectors Tavily RAGFlow").
 ## Source coverage (cumulative)
 - Pull 1: fetched 2026-07-26T17:39:11Z — raw `~/.openwiki/connectors/web-search/raw/2026-07-26T17-38-33-286Z/web-search-results.json`
 - Pull 2: fetched 2026-07-26T18:07:27Z — raw `~/.openwiki/connectors/web-search/raw/2026-07-26T18-07-14-335Z/web-search-results.json`
 - Pull 3: fetched 2026-07-26T18:16:21Z — raw `~/.openwiki/connectors/web-search/raw/2026-07-26T18-16-06-804Z/web-search-results.json`
 - Pull 4: fetched 2026-07-27T18:04:46Z — raw `~/.openwiki/connectors/web-search/raw/2026-07-27T18-04-01-259Z/web-search-results.json`
 - Pull 5: fetched 2026-07-28T18:04:26Z — raw `~/.openwiki/connectors/web-search/raw/2026-07-28T18-03-43-560Z/web-search-results.json`
 - Queries: pulls 1, 2, 4, 5 = 10 queries each; pull 3 = 6 queries (vendor-anchored only)
 - Instance: `web-search-1`
 ---
 ## 2026-07-28 18:04 pull
 Fifth Tavily pull, run as a stand-alone `openwiki personal --update` source ingest. All 10 queries re-run. Two lanes produced genuinely new material evidence (China Order No. 818 regulatory shift; LLM Wiki + OKF shared-memory architecture cluster). The China CDE classification item, CelVivo/TheWell partnership, and Hermes v0.19 Quicksilver rows were not re-anchored in this pull — they remain pinned via `/commitments.md` and the `hermes-agent-v0-19-quicksilver` / `china-cde-cell-gene-therapy-rules-2026` theme rows. Tavily answer-text mis-attribution continues on the 3Brain, Cellink, and Hermes lanes.
 ### China Order No. 818 — accelerated clinical-translation pathway — source-backed
 This is a **new Chinese regulatory signal distinct from the existing CDE classification item**. Order No. 818 (effective 2026-05-01) creates an accelerated pathway for advanced biomedical technologies — including cell therapy and 3D bioprinting — to reach clinical translation at qualified hospitals after demonstrating safety and preliminary efficacy.
 - **LinkedIn (BetaLife SG), 2026-07:** [#ipsc #betalife #celltherapy #ipsc #regenerativemedicine #diabetes #clinicaltranslation #biotechnology #xiamen](https://www.linkedin.com/posts/betalife-sg_betalife-celltherapy-ipsc-activity-7487455334345834497-5hKR). Score 0.779. Explicitly references "Order No. 818, effective May 1, 2026. The regulation introduces an accelerated pathway for eligible advanced biomedical technologies towards regulated clinical translation at qualified hospitals after demonstrating safety and preliminary efficacy." BetaLife (a Singapore-based iPSC company) names this in their post; they cite it as directly relevant to their China clinical-translation journey.
 - **Roots Analysis, 2026-07:** [Cell Therapy Manufacturing Market Size 2035](https://www.rootsanalysis.com/reports/cell-therapy-manufacturing/285.html). Score 0.669. Re-mention of the broader China cell-therapy regulatory landscape (Merck–Bio-Techne $11.3B acquisition, CARsgen China approval). Not an Order No. 818 citation directly, but corroborates the pattern of accelerating China cell-therapy regulatory activity in the same window.
 - **Tavily answer text** independently synthesizes: "China's regulation under Order No. 818, effective May 1, 2026, introduces an accelerated pathway for advanced biomedical technologies, including cell therapy and 3D bioprinting, towards clinical translation at qualified hospitals after demonstrating safety and preliminary efficacy." This is the same content as the BetaLife post — single primary source, with Tavily's synthesis echoing it.
 **Robin relevance:** HIGH for the Chinese pharma R&D / CDMO / biotech customer base. Order No. 818 is the **clinical-translation pathway** counterpart to the CDE classification item (which is about CMC planning). Both items matter: classification scope drives what dossier content vendors need to assemble, and the clinical-translation pathway drives which hospitals can host the first-in-human studies. Together they shape how Femtobiomed positions CelVivo-class bioreactors and 3Brain-class MEA platforms into Chinese accounts.
 **Why source-backed (not watchlist):** the item is published regulatory text (Order No. 818, effective 2026-05-01), not a rumor; BetaLife is a credible industry-actor source citing it in their own clinical-translation context; the Tavily synthesis is consistent with the BetaLife wording. Treat as source-backed pending direct NMPA / State Council corroboration. **Promoted** to `/themes.md` as a new row `china-order-no-818-clinical-translation` and to `/commitments.md` as a verification item.
 ### LLM Wiki + OKF / shared-agent-memory cluster — source-backed (workflow tooling, low priority)
 The `agent personal memory wiki 2026` query returned five same-week sources on a single coherent architecture: a shared agent-memory layer using Andrej Karpathy's LLM Wiki + Google's Open Knowledge Format (OKF) + Model Context Protocol (MCP), positioned to let "every Local AI … share ONE permanent memory." This is directly adjacent to OpenWiki's role.
 - **YouTube (Kai), 2026-07-23:** [LLM Wiki + OKF Every Local AI Now Shares ONE Memory](https://www.youtube.com/watch?v=9ciGYHHOLyU). Score 0.752. Walkthrough of the LLM Wiki + OKF + MCP stack for cross-agent shared memory without vector databases.
 - **Taskade AI, 2026-07:** [The 4 Types of AI Agent Memory Explained (2026)](https://www.taskade.com/wiki/ai-agents/memory-types). Score 0.705. Taskade's own memory architecture (long-term / episodic / short-term / semantic) framed in the same shared-memory terms.
 - **GitHub (SamurAIGPT), 2026-07:** [SamurAIGPT/llm-wiki-agent](https://github.com/SamurAIGPT/llm-wiki-agent). Score 0.694. Open-source "personal knowledge base that builds and maintains itself" — wiki-ingest / wiki-query primitives that mirror Robin's OpenWiki mental model.
 - **LinkedIn (David Bressler, PhD), 2026-07:** [Personal wikis, LLM-maintained knowledge bases, and agent memory systems all eventually hit the same question: How do you know the information in there is still accurate?](https://www.linkedin.com/posts/david-bressler_personal-wikis-llm-maintained-knowledge-activity-7486993623939678208-q4rL). Score 0.614. Adjacent commentary on knowledge-base freshness in agent-maintained wikis.
 - **Reddit r/ClaudeAI, 2026-07-23:** [How many of you are running an LLM wiki with claude code?](https://www.reddit.com/r/ClaudeAI/comments/1v4rdiv/how_many_of_you_are_running_an_llm_wiki_with). Score 0.288 (31 upvotes, 26 comments). Community confirmation that OKF-formatted Obsidian wikis are a working pattern for Claude Code users.
 - **BigDATAwire (Exabase), 2026-07-28:** [Exabase Reports State-of-the-Art Results on BEAM Memory Benchmark](https://www.hpcwire.com/bigdatawire/this-just-in/exabase-reports-state-of-the-art-results-on-beam-memory-benchmark). Score 0.567. Adjacent: BEAM-style memory benchmarks for agent memory engines.
 **Robin relevance:** workflow-tooling, low priority — but the cluster is **substantially more corroborated than the prior HN-only signal**. Five distinct publishers (YouTube creator, SaaS vendor, GitHub, LinkedIn, Reddit) and one adjacent benchmark in the same week all converge on the same OKF + MCP shared-memory architecture. Combined with the existing `agent-memory-architecture` row's three HN Show HN items, the topic now has 8+ distinct sources. **Promote** `agent-memory-architecture` from `watchlist` to `source-backed` and refresh Last seen to 2026-07-28.
 ### 3Brain / Cellink / CellShot / installed-base / Hermes lanes — no new vendor-anchored evidence; Tavily answer-text mis-attribution recurs
 - **3Brain CorePlate MEA 2026:** the Nature [portable semi-dry EEG device paper](https://www.nature.com/articles/s41598-026-52672-8) reappears at score 0.187. Tavily answer text again labels it "3Brain CorePlate MEA 2026 validated in a brain–computer interface study" — the underlying paper is about a portable EEG headset, **not 3Brain's MEA chips**. This is the fourth pull in a row with the same mis-attribution. Do not promote as 3Brain evidence.
 - **Cellink BIO X bioprinter 2026:** Tavily answer text labels the Roche [ADLM 2026 intelligent lab solutions press release](https://www.biospace.com/press-releases/roche-showcases-intelligent-lab-solutions-and-high-precision-instruments-at-adlm-2026-to-help-laboratories-address-workforce-and-workflow-challenges) (0.082) as "Cellink BIO X bioprinter at ADLM 2026" — the underlying source is Roche, not Cellink. The remainder of the lane is industry context (Nova Biomedical–NanoCellect, Massive Bio–GELL, Lumafield Mars X-ray, Repligen–BioLife, BioTechniques bi-weekly). All unrelated to Cellink BIO X / BIONOVA X / Lumen X.
 - **CellShot / CellPick bioprinter 2026:** Tavily honestly says "the CellShot CellPick bioprinter 2026 is not directly mentioned in the provided data sources." Top hits are CCDx whole-cell genomic profiling (0.164), Nova Biomedical–NanoCellect (0.062), AI protein engineering model (0.059), Towards Healthcare cell-and-gene-therapy intelligence infrastructure (0.052), Pluristyx re-mention (0.042). No Femtobiomed vendor signal.
 - **labs CelVivo ClinoStar installed base 2026:** no direct result. Cepheid GeneXpert third-generation ADLM 2026 (score 0.112) and Roche ADLM 2026 (0.143) dominate the top slots and are unrelated to CelVivo installed-base. Query phrasing continues to drift toward competitor/molecular-diagnostic content.
 - **Hermes Agent MiniMax M3 changelog 2026:** Tavily answer text returns Apple product news ("Mismatched M6 and M5 Pro chips", iOS 26.6, POCO Launcher 7.50) — no Hermes Agent, no MiniMax M3, no Hermes changelog in the underlying URLs. Top hit: [MacRumors Next Mac Mini article](https://www.macrumors.com/2026/07/22/mac-mini-m6-m5-pro-chips-rumor/) at 0.074. The v0.19 Quicksilver signal from the prior pull remains the most recent Hermes row; this lane produced nothing new in this 24h window.
 - **OpenWiki connectors Tavily RAGFlow 2026:** Tavily recall still broken. Returns AWWA ACE26 SmartBall X (0.025), Bizora advisory group / Billtrust MCP server (0.026), OpenTug shipping (0.017), Sunvega AI spatial-design workspace (0.016), RightShip maritime (0.016), Inland Tank-Barge Safety Guide (0.015). Only the Billtrust MCP server item is mildly adjacent (MCP-server ecosystem); the rest is unrelated to OpenWiki / Gitea / Wiki.js / RAGFlow / NocoDB / SeaFile. Recommend dropping this lane from future Tavily runs unless the query is rephrased to anchor on product names.
 - **organ-on-chip pharma collaboration 2026:** the Nature [Gut-on-a-Chip culturomics paper](https://www.nature.com/articles/s44385-026-00099-1) (0.986) is the same item surfaced in the 2026-07-26 17:39 pull. Application-domain signal only — folds into the `class-organoid-3d-bioprinting` row without a new evidence note.
 ### Synthesis result
 - **Two new scope-aligned findings:**
  1. **China Order No. 818** — clinical-translation pathway for cell therapy + 3D bioprinting at qualified hospitals, effective 2026-05-01. Source-backed on a single primary source (BetaLife LinkedIn) with Tavily synthesis corroboration. Distinct from the existing `china-cde-cell-gene-therapy-rules-2026` item (classification vs clinical pathway). Promoted to `/themes.md` as new row `china-order-no-818-clinical-translation` and to `/commitments.md` as a verification item.
  2. **LLM Wiki + OKF shared-memory cluster** — five Tavily sources + three prior HN sources all converge on Karpathy's LLM Wiki + Google OKF + MCP shared-memory architecture. Directly adjacent to OpenWiki's role. Promotes existing `agent-memory-architecture` row from `watchlist` to `source-backed`.
 - **No new vendor-anchored evidence** on CelVivo, 3Brain, Cellink, CellShot/TriArm, or Hermes this pull. The prior vendor-anchored items (CelVivo+TheWell, Hermes v0.19 Quicksilver) remain on disk and referenceable; the Hermes row's Last seen is **not** refreshed because the underlying URLs in this pull returned Apple-product noise.
 - **Tavily answer-text mis-attribution pattern persists** on 3Brain (4th pull), Cellink (4th pull), and Hermes (1st pull). This is a Tavily-side quality issue; treat Tavily answer text as untrusted and only the underlying URLs as evidence. Continued recommendation: narrow future pulls to vendor-name-anchored queries only.
 - **OpenWiki / RAGFlow / agent-memory lane behavior changed.** The lane still produces zero OpenWiki/RAGFlow/SeaFile/NocoDB/Gitea results, but the **agent-personal-memory-wiki** lane is now high-signal for the OKF/LLM Wiki architecture — strong enough to promote the existing `agent-memory-architecture` row.
 ---
 ## 2026-07-29 18:03 pull
 Sixth Tavily pull, run as a stand-alone `openwiki personal --update` source ingest. All 10 queries re-run. Three lanes produced material new evidence: Cellink BIO X Gen 3 first-time vendor-anchored signal; China CGT regulatory landscape material updates (Merck–Bio-Techne, CARsgen satri-cel, gene-editing trial death + backlash); Hermes Agent v0.19 documentation continues (configuration.md, api-server.md). The CelVivo/TheWell xeno-free and China Order No. 818 items remain pinned in `/commitments.md`. The agent-memory-architecture cluster continues to grow. Tavily answer-text mis-attribution persists on Q2/Q3 (3Brain / Cellink) but the underlying URLs are now vendor-anchored for Cellink — a first.
 ### Cellink BIO X Gen 3 / BIO X6 — first vendor-anchored Cellink signal — source-backed
 This is the **first vendor-anchored Cellink BIO X / BIO X6 / BIO X Gen 3 signal in any Tavily pull**. Prior pulls returned only MO:BOT, Roche, Cepheid, Velo3D, Cellares-Papillon, or generic bioprinting market reports — never Cellink product names in a vendor/customer context. Three same-week sources confirm Cellink product activity:
 - **LinkedIn (Nuclear Mechano-Oncology), no exact date in 2026-07:** [BIO X Gen 3 Bioprinter Installed and Trained](https://www.linkedin.com/posts/nuclear-mechano-oncology_exciting-news-from-our-lab-our-new-bio-activity-7486350933371543552-CBoV). Score 0.601. A customer lab (Nuclear Mechano-Oncology) announces the install + first hands-on training of a BIO X Gen 3 bioprinter, with team members Ines Papak, Kamil Łangowski, Julia Jała named. Positions BIO X Gen 3 as "an important addition to our work on advanced 3D cell culture models and the development of more physiologically relevant cancer research platforms."
 - **LinkedIn (CELLINK official channel), 2026-07-28:** [From Star Trek to the Clinic: 3D Bioprinting Facility is Engineering Molecules for Patient Implantation](https://www.linkedin.com/posts/cellink_from-star-trek-to-the-clinic-3d-bioprinting-activity-7487839428997046272-myqA). Score 0.287. CELLINK's own organization page (26,186 followers) highlights the University of Miami 3D Bioprinting Facility using CELLINK's BIO X6 in the toolkit for tissue engineering and patient-specific implants. Companion article from InventUM.
 - **LinkedIn (Biomedical 3D Printer Market report), 2026-07-28:** [Biomedical 3D Printer Market Size and Growth at a 4.7% CAGR from 2026 to 2033](https://www.linkedin.com/pulse/biomedical-3d-printer-market-size-growth-47-bstsf). Score 0.659. Third-party market report explicitly names Cellink as a major player with "a significant uptick in their revenue stream" following "strategic acquisitions and increased market penetration" and notes Cellink's "focus on sustainable and customizable bioinks."
 - **apellaser.ro, 2026-07-24:** [How to Choose a 3D Bioprinter: Practical Selection Guide](https://apellaser.ro/en/bioprinter-selection-guide). Score 0.303. Independent practical guide explicitly names "BIO X Gen 3 is the general-purpose choice for laboratories that need flexible extrusion and up to three interchangeable printheads or tools." Vendor-anchored reference, not a press release.
 - **Tavily answer text** describes "The Cellink BIO X bioprinter, specifically the Gen 3 model, is a versatile tool for laboratories requiring flexible extrusion and up to three interchangeable printheads" — this time the answer text correctly identifies Cellink product naming (though it includes hallucinated "Gen 3" details in some phrases; the underlying URLs are the source of truth).
 **Robin relevance:** HIGH. First vendor-anchored Cellink signal after 5 prior pulls of zero Cellink product mentions. The Nuclear Mechano-Oncology install is an Eastern European customer reference; the U. Miami BIO X6 mention is the same University of Miami 3D Bioprinting Facility that has been a recurring Cellink reference in industry press; the market report independently corroborates Cellink revenue growth. Promoted to `/commitments.md` as `cellink-bio-x-gen3-customer-evidence` for next-vendor-check verification (parallel structure to the CelVivo+TheWell row).
 ### China cell & gene therapy regulatory landscape — material updates — source-backed
 The Q7 lane surfaced four distinct new items that materially update the existing `/commitments.md` `china-cde-cell-gene-therapy-rules-2026` and `china-order-no-818-clinical-translation` items. The gene-editing trial death + regulatory backlash is the most consequential — it directly affects how Robin positions 3Brain MEA + CelVivo ClinoReactor + Cellink BIO X for Chinese pharma R&D / CDMO / biotech customers.
 - **Roots Analysis, 2026-07-24:** [Cell Therapy Manufacturing Market Size 2035](https://www.rootsanalysis.com/reports/cell-therapy-manufacturing/285.html). Score 0.669. Two new data points from the same Roots Analysis page: (a) **June 2026: Merck agreed to acquire Bio-Techne for ~$11.3B** to strengthen life-science capabilities across bioprocessing, advanced therapeutics, and integrated workflow solutions for cell-and-gene-therapy developers; (b) **June 2026: CARsgen Therapeutics received China NMPA approval for satri-cel, a CAR-T therapy for solid-tumor stomach cancer** — described as "an important milestone for solid tumor CAR-T therapies" expected to increase demand for specialized CAR-T manufacturing in Asia-Pacific.
 - **BioSpace, 2026-07-27:** [Summit, Merck must navigate new regulatory terrain in China-first cancer landscape](https://www.biospace.com/drug-development/summit-merck-must-navigate-new-regulatory-terrain-in-china-first-cancer-landscape). Score 0.535. Frames the broader pattern of China-first cancer-drug development: Stifel analysts (2026-07-22 note) argue the HARMONi 2-year follow-up data is "a strong counter" to the "China data would not translate" bear argument. Implications for CDMO and instrument vendors supporting both Western and China-first pipelines.
 - **Straits Times, 2026-07-24:** [Patient death in China gene-editing trial draws fire: Journal](https://www.straitstimes.com/asia/east-asia/patient-death-in-china-gene-editing-trial-draws-fire-journal). Score 0.313. A patient (later confirmed as a 6-year-old girl in follow-up coverage) died in an experimental gene-editing trial in China; the case is drawing published scrutiny of China's gene-therapy regulatory regime.
 - **LiveScience, 2026-07-24:** [An experimental gene therapy killed a 6-year-old girl in China. Her parents are seeking accountability](https://www.livescience.com/health/genetics/6-year-old-in-china-dies-after-experimental-treatment-investigation-finds-raising-questions-about-the-countrys-gene-therapy-regulations). Score 0.145. Investigation-level coverage: raises "questions about the country's gene therapy regulations."
 - **SCMP, 2026-07-29:** [Is China's biotech boom at risk? Fear of policy backlash after death in gene-editing trial](https://amp.scmp.com/news/china/science/article/3362253/chinas-biotech-boom-risk-fear-policy-backlash-after-death-gene-editing-trial). Score 0.203. Frames the same death as a potential inflection point for China's biotech regulatory regime — "Fear of policy backlash." Published same day as this Tavily pull, which is what surfaces it.
 **Robin relevance:** HIGH (the gene-editing trial death item especially). The Merck–Bio-Techne acquisition and CARsgen satri-cel approval are positive indicators of the China CGT manufacturing environment. The gene-editing trial death + published regulatory scrutiny is the inverse signal: it could foreshadow stricter CDE / NMPA / hospital-level oversight, which would affect (a) qualification timelines for the CellShot-TriArm and ClinoReactor-class deals Robin has in flight, and (b) which "qualified hospitals" under Order No. 818 remain eligible. Promoted to `/commitments.md` as `china-cgt-2026-july-developments` to track this as a single follow-up item.
 ### Organ-on-chip pharma collaboration 2026 — source-backed (application-domain)
 The Q4 lane returned two strong same-week items on organ-on-chip / pharma collaboration:
 - **Business Weekly, 2026-07-24:** [Business Weekly Awards 2026: 44 shortlisted companies revealed for Cambridge Tech and Life Sciences showcase](https://www.businessweekly.co.uk/posts/business-weekly-awards-2026-44-shortlisted-companies-revealed-for-cambridge-tech-and-life). Score 0.754. **CN Bio** (Chesterford Research Park) shortlisted for the OOC PhysioMimix platform; profile explicitly cites a **$11m funding deal with Ligand Pharmaceuticals (Florida)** and a **co-development agreement with Sequel Med Tech LLC (New Hampshire)** as last-year's announcements.
 - **SelectScience, 2026-07-28:** [Organ-Chips reach new frontiers with NASA's AVATAR project and next-gen preclinical testing](https://www.selectscience.net/article/organ-chips-reach-new-frontiers-with-avatar-and-next-gen-preclinical-testing). Score 0.736. NASA AVATAR (A Virtual Astronaut Tissue Analog Response) project uses OOC devices to study deep-space effects on human health; features Emulate's 96-chip AVA Emulation System helping pharma transition to human-relevant testing under FDA Modernization Act 2.0 / UK guidelines.
 - **Nature, 2026-07-24:** [Engineering human Gut-on-a-Chip culturomics](https://www.nature.com/articles/s44385-026-00099-1) reappears at score 0.367 (re-mention from pulls 1 + 5).
 **Robin relevance:** application-domain only — folds into the existing `class-organoid-3d-bioprinting` row. CN Bio / Emulate are not one of Robin's 4 vendor lines, but both are competitive/positioning signal for CelVivo-class bioreactors at pharma R&D accounts. NASA AVATAR is a high-visibility OOC application milestone.
 ### Hermes Agent v0.19 documentation refresh — source-backed (workflow tooling, low priority)
 Q8 returned two NousResearch/hermes-agent repo documentation updates and one third-party M3-vs-OpenClaw comparison. The docs confirm v0.19+ work is still landing in the 2026-07-26 → 2026-07-29 window — same row as the v0.19 Quicksilver signal, more sources.
 - **GitHub (NousResearch/hermes-agent `configuration.md`), 2026-07-26:** [Iteration Budget](https://github.com/NousResearch/hermes-agent/blob/main/website/docs/user-guide/configuration.md). Score 0.590. Documents the iteration-budget behavior change: "earlier builds warned the model at 70%/90% budget, which caused models to abandon complex tasks prematurely and was removed in April 2026." Now at default 500 turns, Hermes injects one wrap-up message at 500/500 with a single grace call. Story-worthy because it is a deliberate quality change, not just a number.
 - **GitHub (NousResearch/hermes-agent `features/api-server.md`), 2026-07-27:** [POST /v1/runs/{run_id}/stop + /approval endpoints](https://github.com/NousResearch/hermes-agent/blob/main/website/docs/user-guide/features/api-server.md). Score 0.367. Documents the new `/v1/runs/{run_id}/stop` and `/v1/runs/{run_id}/approval` endpoints (returning `{"status": "stopping"}` and resolving approval policies). Sample JSON now uses `"model":"MiniMax-M3"` with provider `"minimax"` — M3 is the documented default.
 - **MyClaw.ai, 2026-07-29:** [OpenClaw vs MiniMax Agent: Which AI Agent Should You Use in 2026?](https://myclaw.ai/blog/openclaw-vs-minimax-agent). Score 0.543. Third-party comparison: **OpenClaw supports MiniMax through OAuth with a Token Plan or API key.** M3 handles primary reasoning; M2.7 variants remain available. Multimodal (image, video, music, speech, web search) supported across M3 and M2.7.
 - **Instagram (Sriram Varadharajan), no exact date in 2026-07:** [AI COMMAND CENTER TRIAL REEL — MiniMax M3 announcement](https://www.instagram.com/reel/DbVydtNj46Z). Score 0.497. Reels text references MiniMax M3 launch ("longer context, capability uplift over M2") and open-source readiness. Adjacent to MiniMax-M3 theme row.
 **Robin relevance:** WORKFLOW TOOLING (low priority). The configuration.md change is a Hermes-side behavior update Robin's daily-driver stack benefits from; the api-server.md endpoints are runtime-control surfaces OpenWiki's MCP integration could exploit; MyClaw.ai confirms MiniMax M3 as the operational model for both OpenClaw and Hermes. Folded into the existing `hermes-agent-v0-19-quicksilver` and `MiniMax-m3` theme rows — refreshes Last seen but does not spawn a new row.
 ### Agent-memory-architecture cluster grows — source-backed (workflow tooling, low priority)
 Q10 returned four new sources that further corroborate the existing `agent-memory-architecture` theme row. Combined with the prior 5 Tavily + 3 HN sources, the cluster now has 12+ distinct publishers converging on shared / open-format / persistent agent-memory architectures:
 - **HPCwire, 2026-07-28:** [Exabase Reports State-of-the-Art Results on BEAM Memory Benchmark](https://www.hpcwire.com/aiwire/2026/07/28/exabase-reports-state-of-the-art-results-on-beam-memory-benchmark). Score 0.624. Exabase M-1 achieves highest reported score at every scale: **76.9% at 100K tokens, 75.0% at 1M tokens, 68.0% at 10M tokens**, using Gemini 3 Flash (a model "up to six times cheaper and faster" than Gemini 3 Pro used by every other leading system). 20% fewer tokens per query than next-best system.
 - **Hackernoon (Moorcheh.ai CTO), 2026-07-28:** [Agent Memory Has a Lock-In Problem. Open Formats Are How We Fix It.](https://hackernoon.com/agent-memory-has-a-lock-in-problem-open-formats-are-how-we-fix-it). Score 0.605. Frames the lock-in problem explicitly: "Your agent has been in production for a year. … thousands of memories: user preferences, resolved decisions, corrections, domain facts. Now you want to move to a different memory system — better retrieval, better pricing, whatever. What's your migration path?" Argues for **Diffability** ("`git diff` shows exactly what your agent learned between two commits"), **Reviewability** ("Memory changes can go through pull requests like code"), and **Auditability** ("Regulated environment? Your …"). This is the most explicit OpenWiki-aligning post yet — pull-request review of agent memory is exactly what OpenWiki's synthesis workflow does.
 - **Towards Data Science, 2026-07-24:** [Context Windows Forget What Matters — I Built a Usage-Reinforced Decay Engine for AI Agent Memory](https://towardsdatascience.com/context-windows-forget-what-matters-i-used-a-140-year-old-psychology-paper-to-fix-ai-memory). Score 0.576. Uses Ebbinghaus forgetting curve (1885) to design a spaced-repetition decay engine for agent memory. Cites the open-source **YourMemory** project (Mishra, 2026) as another Ebbinghaus-forgetting-curve implementation. Robin-relevant because OpenWiki's wiki synthesis itself is a form of spaced-repetition knowledge curation.
 - **The Register, 2026-07-29:** [MinIO pitches persistent memory for agents with work to finish](https://www.theregister.com/storage/2026/07/29/minio-pitches-persistent-memory-for-agents-with-work-to-finish/5280407). Score 0.425. MinIO **AIStor Memory** for long-running multi-step agent workflows. Example use cases: software engineering agents across large codebases; deep research spanning hours or days; human-in-the-loop workflows that pause and resume; enterprise AI systems handling regulated data. The piece argues "agent-generated work accumulates, memory created for individual agents can become a shared organizational record built by humans and machines" — and that where that record lives is the architectural question OpenWiki sits at.
 **Robin relevance:** WORKFLOW TOOLING (low priority). The cluster is now 12+ sources. The Hackernoon/Moorcheh.ai piece is the strongest single source for OpenWiki alignment (pull-request review of agent memory maps 1:1 onto OpenWiki's synthesis). The MinIO piece confirms enterprise infrastructure vendors are now treating "shared organizational memory built by humans and machines" as a product category. Refreshes `agent-memory-architecture` Last seen to 2026-07-29 and adds to evidence count.
 ### 3Brain / CellShot / installed-base / OpenWiki-RAGFlow / Tavily answer-text quality — same pattern
 - **3Brain CorePlate MEA 2026:** Nature [portable semi-dry EEG device paper](https://www.nature.com/articles/s41598-026-52672-8) reappears at score 0.187 — **fifth pull in a row with the same mis-attribution**. Tavily answer text again labels it "3Brain CorePlate MEA 2026 … validated for its application in brain–computer interface solutions." Underlying paper is a portable EEG headset, not 3Brain MEA chips. Do not promote as 3Brain evidence.
 - **Cellink BIO X bioprinter 2026:** as noted above, this pull is the first to return real Cellink product evidence. Tavily answer text was finally correct on the Cellink side this time ("Cellink BIO X bioprinter, specifically the Gen 3 model, is a versatile tool for laboratories requiring flexible extrusion and up to three interchangeable printheads").
 - **CellShot / CellPick bioprinter 2026:** Tavily honestly says "The CellShot CellPick bioprinter 2026 is not mentioned in the provided data sources." Top hit is **GEN "Large Bioprinted Tissues Get a Precision Boost"** (2026-07-29 12:00:52 GMT, score 0.259) — application-domain news, no Femtobiomed vendor signal. The same GEN article reappears in Q1 (0.037), Q2 (0.032), and Q5 (0.259). Worth a note in `class-organoid-3d-bioprinting` evidence column.
 - **labs CelVivo ClinoStar installed base 2026:** Tavily answer text returns a hallucinated claim: "As of today, July 29, 2026, the CelVivo ClinoStar is being installed in new A-Level (H2) science labs, such as the one opening in Eclat @ Henderson in August 2026." **No URL in the result set mentions CelVivo, ClinoStar, A-Level, H2, Eclat, or Henderson.** This is a fabricated Tavily answer — flag and ignore. The actual top hits are Instagram reels and the UFS Alzheimer's story, all unrelated to CelVivo.
 - **Hermes Agent MiniMax M3 changelog 2026:** as noted above — first pull with non-noise Hermes/M3 evidence (configuration.md, api-server.md, MyClaw.ai, Instagram reel). Promotes the existing rows instead of spawning new ones.
 - **OpenWiki connectors Tavily RAGFlow 2026:** recall still broken. Returns Roche ADLM 2026 (0.043), Nature chemical-reaction pathway algorithm (0.029), SmartBall X water infrastructure (0.025), exposure-management AI-attack cybersecurity (0.023), HID workforce unit transfer (0.019), **GEN "Downstream Purification Platform Breaks Complex Vector Bottleneck"** (0.017), RightShip maritime (0.016), insurance payment (0.016). Only the GEN vector-bottleneck item is mildly adjacent (cell-and-gene-therapy manufacturing); the rest is noise. Recommend dropping this lane from future Tavily runs.
 ### Synthesis result
 - **Three new scope-aligned findings:**
  1. **Cellink BIO X Gen 3 / BIO X6 customer evidence** — first vendor-anchored Cellink signal in any Tavily pull. Multi-source (Nuclear Mechano-Oncology LinkedIn install, CELLINK official LinkedIn BIO X6 at U. Miami, third-party market report, appellaser selection guide). Promoted to `/commitments.md` as `cellink-bio-x-gen3-customer-evidence`.
  2. **China CGT regulatory landscape updates** — Merck–Bio-Techne $11.3B acquisition (June 2026); CARsgen satri-cel CAR-T approval for stomach cancer (June 2026); **gene-editing trial death + regulatory backlash** (Straits Times / LiveScience / SCMP coverage 2026-07-24 → 2026-07-29). Promoted to `/commitments.md` as `china-cgt-2026-july-developments` to track the gene-editing-death + China-biotech-backlash signal alongside the existing classification and Order No. 818 items.
  3. **Hermes Agent v0.19 docs continue** — `configuration.md` iteration-budget behavior change (April 2026, documented 2026-07-26) + `api-server.md` new stop / approval endpoints (2026-07-27). Refreshes Last seen for `hermes-agent-v0-19-quicksilver`. MyClaw.ai confirms MiniMax M3 + M2.7 as the operational models for both OpenClaw and Hermes — refreshes Last seen for `MiniMax-m3`.
 - **One application-domain cluster strengthens:** organ-on-chip (CN Bio + Ligand + Sequel Med Tech; NASA AVATAR + Emulate). Folds into the existing `class-organoid-3d-bioprinting` row without spawning a new theme.
 - **Agent-memory-architecture cluster grows to 12+ distinct sources.** Hackernoon/Moorcheh.ai "Agent Memory Has a Lock-In Problem" is the strongest single OpenWiki-aligning source yet. Refreshes Last seen for `agent-memory-architecture`.
 - **Tavily answer-text mis-attribution continues** on Q2 3Brain (5th pull). This is now a Tavily-side quality issue worth flagging in connector notes.
 - **New Tavily hallucination pattern on Q6:** the Tavily answer text invented a specific claim about CelVivo ClinoStar being installed in "new A-Level (H2) science labs, such as the one opening in Eclat @ Henderson in August 2026." No underlying URL supports this. Treat Tavily answer text on the installed-base query as fabrication and ignore.
 - **No 3Brain / CellShot-TriArm / OpenWiki-RAGFlow direct evidence** in this pull.
 ## Source coverage (cumulative)
 - Pull 1: fetched 2026-07-26T17:39:11Z — raw `~/.openwiki/connectors/web-search/raw/2026-07-26T17-38-33-286Z/web-search-results.json`
 - Pull 2: fetched 2026-07-26T18:07:27Z — raw `~/.openwiki/connectors/web-search/raw/2026-07-26T18-07-14-335Z/web-search-results.json`
 - Pull 3: fetched 2026-07-26T18:16:21Z — raw `~/.openwiki/connectors/web-search/raw/2026-07-26T18-16-06-804Z/web-search-results.json`
 - Pull 4: fetched 2026-07-27T18:04:46Z — raw `~/.openwiki/connectors/web-search/raw/2026-07-27T18-04-01-259Z/web-search-results.json`
 - Pull 5: fetched 2026-07-28T18:04:26Z — raw `~/.openwiki/connectors/web-search/raw/2026-07-28T18-03-43-560Z/web-search-results.json`
 - Pull 6: fetched 2026-07-29T18:03:26Z — raw `~/.openwiki/connectors/web-search/raw/2026-07-29T18-02-29-119Z/web-search-results.json`
 - Pull 7: fetched 2026-07-30T18:04:41Z — raw `~/.openwiki/connectors/web-search/raw/2026-07-30T18-03-34-547Z/web-search-results.json`
 - Queries: pulls 1, 2, 4, 5, 6, 7 = 10 queries each; pull 3 = 6 queries (vendor-anchored only)
 - Instance: `web-search-1`
 ---
 ## 2026-07-30 18:04 pull
 Seventh stand-alone Tavily pull; all 10 queries re-ran. The material additions are the first credible direct 3Brain result in this lane, lower-confidence CelVivo ClinoStar campaign snippets, authoritative FDA organ-on-chip/NAMs context, and continued Hermes/OpenWiki/agent-memory evidence. Cellink, CellShot, and China-policy results were predominantly re-mentions or attribution noise.
 ### 3Brain CorePlate conference and application positioning — confirmed vendor signal
 - **3Brain organization material via LinkedIn, surfaced with a 2026-07-25 result:** [ISSCR 2026 / CorePlate-enabled HD-MEA campaign](https://www.linkedin.com/posts/lucyschmidt_neuroscience-cellbiology-brain-activity-7486837823321292800-F8Rk) (score 0.857) positions CorePlate for high-resolution, scalable functional readouts from iPSC-derived neuronal models, brain organoids, assembloids, and neuronal/cardiomyocyte screens; it names ISSCR booth 412.
 - **3Brain company LinkedIn:** [3Brain AG](https://jp.linkedin.com/company/3brain) (score 0.839) adds ELRIG Drug Discovery booth 4 and describes multi-well HD-MEA use for mechanistic studies and higher-throughput screening across neuronal/cardiac models, 3D spheroids, and brain organoids. The page aggregates multiple posts, so individual event timing still needs a direct vendor check.
 - **3Brain official site:** [High-Density Microelectrode Array](https://www.3brain.com) (score 0.689) independently anchors CorePlate 3D / Accura-3D, brain-organoid and Pharma-on-Chip applications, and BrainWave 6. The pull contains no new CorePlate load-force, Sample Holder Set, or patent detail.
 - **Robin relevance:** first credible direct 3Brain evidence after five pulls dominated by an unrelated EEG-paper mis-attribution. Added `/commitments.md#3brain-coreplate-2026-conference-positioning-verify-current-coreplate-campaign-and-retrieve-application-material-on-next-3brain-check` for the required next-vendor-check verification.
 ### CelVivo ClinoStar / ClinoStar 2 campaign snippets — watchlist
 - **Instagram snippets:** [ClinoStar webinar copy](https://www.instagram.com/p/DbaUZjIjMgK) (score 0.335) describes clinostat-based simulated microgravity; [NexUs Locus live-demo copy](https://www.instagram.com/reel/DbKYC4NBtrN) (published 2026-07-24; score 0.291) promises on-site growth of larger, more physiologically relevant organoids; a separate [ClinoStar 2 post](https://www.instagram.com/p/DbSl7nkoFjK) (score 0.188) positions the system for NAMs and human-based drug-safety/efficacy evaluation.
 - Account provenance and dates are incomplete in the result set, and the query answer extrapolates an “installed base” that none of the URLs documents. One duplicate result carried a malformed/spam-like query string and was discarded.
 - The TheWell Bioscience xeno-free guide reappeared but adds nothing beyond the existing `celvivo-clinoreactor-thewell-bioscience-xeno-free` commitment.
 - **Robin relevance:** potentially useful current CelVivo messaging, but not proof of a launch, installation, or customer win. Added `/commitments.md#celvivo-clinostar-2-nams-demo-2026-verify-product-naming-and-campaign-provenance-on-next-celvivo-check` as a verification lead.
 ### Organ-on-chip, bioprinting, and regulatory context
 - **FDA, content current 2026-07-27:** [Accelerating and Modernizing Early and Late-Stage Clinical Development](https://www.fda.gov/industry/fda-actions-accelerate-and-modernize-early-and-late-stage-clinical-development) (score 0.566) explicitly includes human organ-on-chip systems among NAMs, alongside June 2026 cell/gene-therapy draft guidance and May 2026 streamlined nonclinical-safety guidance. This is authoritative US regulatory context, not a China-policy update.
 - **Molecular Cancer, published 2026-07-28:** [patient-derived 3D-bioprinted primary liver-cancer models](https://link.springer.com/article/10.1186/s12943-026-02751-1) (score 0.347), from Peking Union Medical College Hospital, adds China-based translational application evidence.
 - **npj Biomedical Innovations, published 2026-07-29:** [Challenges and opportunities in generating microvasculature using bioprinting techniques](https://www.nature.com/articles/s44385-026-00100-x) (score 0.177) adds application-domain context. The prior MDPI hepatic-organoid volumetric-bioprinting paper also reappeared.
 - China Order No. 818, CDE classification, CARsgen, CN Bio, NASA AVATAR, and Emulate results are re-mentions already captured in pull 5 or pull 6; no NMPA/CDE-direct corroboration appeared.
 ### Workflow tooling and agent memory — source-backed, low priority
 - **NousResearch Hermes Agent docs:** [api-server.md](https://github.com/NousResearch/hermes-agent/blob/main/website/docs/user-guide/features/api-server.md) (score 0.729) now exposes a July 2026 per-profile `API_SERVER_KEY` breaking-change warning and a runs API for long-form sessions, extending the stop/approval endpoint evidence captured in pull 6. A third-party Hermes Atlas report summarizes broader July changes; ReleaseBot's OpenClaw notes are not treated as Hermes release evidence.
 - **OpenWiki official repository:** [langchain-ai/openwiki](https://github.com/langchain-ai/openwiki) (score 0.416) is finally returned by the previously noisy OpenWiki/RAGFlow query and confirms the current connector set and user-authored instruction-brief behavior. It is a discovery/retrieval improvement, not evidence of a new OpenWiki release; no direct RAGFlow shift appeared.
 - **LLM-wiki pattern:** [arXiv 2607.24759v1](https://arxiv.org/html/2607.24759v1) (score 0.792) explicitly describes an LLM-maintained interlinked Markdown wiki between raw sources and agents; [LLM Wiki v2](https://gist.github.com/rohitg00/2067ab416f7bbe447c1977edaaa681e2) surfaced on 2026-07-30 (score 0.759) adds segmentation, librarian/retrieval, and schema-design discussion.
 - **Enterprise agent memory:** MinIO's [AIStor Memory announcement](https://www.hpcwire.com/bigdatawire/this-just-in/minio-launches-aistor-memory-the-enterprise-memory-foundation-for-agentic-ai) (2026-07-29; score 0.576) and [SiliconANGLE coverage](https://siliconangle.com/2026/07/29/miniio-debuts-aistor-memory-long-term-memory-ai-agents-need-scale-safely) (2026-07-30; score 0.524) corroborate the persistent, governed memory category already indexed as `agent-memory-architecture`.
 ### Exclusions and synthesis result
 - **Cellink:** Tavily's answer attributes the MDPI volumetric-bioprinting paper to BIO X, but the underlying result excerpt does not name CELLINK. Faryal Zahid's portfolio names Lumen X / BIO ONE / BIO X manuals but is documentation-history context, not a release or customer win. The existing Cellink commitment is unchanged.
 - **Femtobiomed:** the CellShot/CellPick query returned only a generic consumer 3D-printing article; its CellShot attribution is unsupported. No CellShot, CellPick, or TriArm evidence was promoted.
 - **Promoted:** two vendor-verification commitments (3Brain and CelVivo). **Not promoted:** no new theme row, open question, personal-logistics item, or China-regulatory commitment.
 - **Coverage:** fetched `2026-07-30T18:04:41.115Z`; 10 queries; raw `~/.openwiki/connectors/web-search/raw/2026-07-30T18-03-34-547Z/web-search-results.json`; instance `web-search-1`.
 ---
 ## 2026-07-31 18:04 pull
 Eighth Tavily pull, run as a stand-alone `openwiki personal --update` source ingest. **All 10 queries returned a structured `"error": "fetch failed"`** — no usable evidence this cycle. The same queries succeeded in pulls 1–7, so this looks like a Tavily-side / upstream network outage rather than a query-phrasing or scope problem. No theme refresh, no new commitments, no new open questions.
 ### Per-query result
 Every query in the 10-query lane returned the same structured error (no answer text, no result URLs):
 - `CelVivo ClinoReactor spheroid 2026` — error
 - `3Brain CorePlate MEA 2026` — error
 - `Cellink BIO X bioprinter 2026` — error
 - `organ-on-chip pharma collaboration 2026` — error
 - `CellShot CellPick bioprinter 2026` — error
 - `labs CelVivo ClinoStar installed base 2026` — error
 - `China cell therapy 3D bioprinting regulation 2026` — error
 - `Hermes Agent MiniMax M3 changelog 2026` — error
 - `OpenWiki connectors Tavily RAGFlow 2026` — error
 - `agent personal memory wiki 2026` — error
 ### Synthesis result
 - **No new vendor-anchored or application-domain evidence.** Tavily returned a structured `fetch failed` error on every query. All seven prior pulls remain the canonical evidence base; no wiki synthesis update is warranted this run.
 - **Operational note for the connector.** This is the first fully-failed pull since the Tavily lane was activated on 2026-07-26. If the next pull also fails, consider checking `TAVILY_API_KEY` validity, Tavily status page, or rate-limit posture before continuing to schedule the lane.
 - **Coverage:** fetched `2026-07-31T18:06:36.672Z`; 10 queries (all failed); raw `~/.openwiki/connectors/web-search/raw/2026-07-31T18-04-55-956Z/web-search-results.json`; instance `web-search-1`.
 ## 2026-08-01 18:09 pull
 **Gap-fill.** Pull 9 was ingested on 2026-08-01 between Tavily's last documented failed run (2026-07-31 pull 8) and this current run, but the prior `openwiki personal --update` cycle was git-repo-only and did not record a Tavily section. Pulling the raw data forward here so the connector's outage streak is auditable. **All 10 queries returned a structured `"error": "fetch failed"`** — same pattern as pull 8.
 ### Per-query result
 Every query in the 10-query lane returned the same structured error (no answer text, no result URLs):
 - `CelVivo ClinoReactor spheroid 2026` — error
 - `3Brain CorePlate MEA 2026` — error
 - `Cellink BIO X bioprinter 2026` — error
 - `organ-on-chip pharma collaboration 2026` — error
 - `CellShot CellPick bioprinter 2026` — error
 - `labs CelVivo ClinoStar installed base 2026` — error
 - `China cell therapy 3D bioprinting regulation 2026` — error
 - `Hermes Agent MiniMax M3 changelog 2026` — error
 - `OpenWiki connectors Tavily RAGFlow 2026` — error
 - `agent personal memory wiki 2026` — error
 ### Synthesis result
 - **No new vendor-anchored or application-domain evidence.** Backfills the gap between pull 8 and pull 10; pull 7 (2026-07-30) remains the canonical last successful Tavily pull.
 - **Coverage:** fetched `2026-08-01T18:09:15.810Z`; 10 queries (all failed); raw `~/.openwiki/connectors/web-search/raw/2026-08-01T18-07-35-101Z/web-search-results.json`; instance `web-search-1`.
 ---
 ## 2026-08-02 18:07 pull
 Tenth Tavily pull, run as a stand-alone `openwiki personal --update` source ingest on this connector. **All 10 queries returned a structured `"error": "fetch failed"`** — same pattern as pulls 8 (2026-07-31) and 9 (2026-08-01). This makes **three consecutive fully-failed Tavily pulls**, paralleling the HN connector's third-consecutive-empty-pull streak flagged in `/quickstart.md`'s Current status. No scope or query-phrasing change relative to pulls 1–7, which all produced usable evidence; the failure is Tavily-side / upstream.
 ### Per-query result
 Every query in the 10-query lane returned the same structured error (no answer text, no result URLs):
 - `CelVivo ClinoReactor spheroid 2026` — error
 - `3Brain CorePlate MEA 2026` — error
 - `Cellink BIO X bioprinter 2026` — error
 - `organ-on-chip pharma collaboration 2026` — error
 - `CellShot CellPick bioprinter 2026` — error
 - `labs CelVivo ClinoStar installed base 2026` — error
 - `China cell therapy 3D bioprinting regulation 2026` — error
 - `Hermes Agent MiniMax M3 changelog 2026` — error
 - `OpenWiki connectors Tavily RAGFlow 2026` — error
 - `agent personal memory wiki 2026` — error
 ### Synthesis result
 - **No new vendor-anchored or application-domain evidence.** Pull 7 (2026-07-30) remains the canonical last successful Tavily pull. All theme rows (`class-organoid-3d-bioprinting`, `china-cde-cell-gene-therapy-rules-2026`, `china-order-no-818-clinical-translation`, `MiniMax-m3`, `hermes-agent-v0-19-quicksilver`, `openwiki-brand`, `agent-memory-architecture`) keep their 2026-07-30 / 2026-07-29 / 2026-07-16 Last seen. No `commitments.md` and no `open-questions.md` change.
 - **Operational note for the connector.** Pull 10 is the third consecutive fully-failed pull (after pulls 8 and 9). The pull 8 note said: "If the next pull also fails, consider checking `TAVILY_API_KEY` validity, Tavily status page, or rate-limit posture before continuing to schedule the lane." That advice now applies; one fully-failed pull was a probable outage, two was a sustained outage, three is **a confirmed Tavily-side outage**. Recommend an unscheduled check of `TAVILY_API_KEY`, Tavily status, and rate-limit posture on disk before scheduling the next scheduled pull. Without that, the Tavily lane should be paused (per the same posture already recommended for the HN lane in `/quickstart.md`).
 - **Coverage:** fetched `2026-08-02T18:07:53.246Z`; 10 queries (all failed); raw `~/.openwiki/connectors/web-search/raw/2026-08-02T18-06-12-521Z/web-search-results.json`; instance `web-search-1`.
 ## Source coverage (cumulative)
 - Pull 1: fetched 2026-07-26T17:39:11Z — raw `~/.openwiki/connectors/web-search/raw/2026-07-26T17-38-33-286Z/web-search-results.json`
 - Pull 2: fetched 2026-07-26T18:07:27Z — raw `~/.openwiki/connectors/web-search/raw/2026-07-26T18-07-14-335Z/web-search-results.json`
 - Pull 3: fetched 2026-07-26T18:16:21Z — raw `~/.openwiki/connectors/web-search/raw/2026-07-26T18-16-06-804Z/web-search-results.json`
 - Pull 4: fetched 2026-07-27T18:04:46Z — raw `~/.openwiki/connectors/web-search/raw/2026-07-27T18-04-01-259Z/web-search-results.json`
 - Pull 5: fetched 2026-07-28T18:04:26Z — raw `~/.openwiki/connectors/web-search/raw/2026-07-28T18-03-43-560Z/web-search-results.json`
 - Pull 6: fetched 2026-07-29T18:03:26Z — raw `~/.openwiki/connectors/web-search/raw/2026-07-29T18-02-29-119Z/web-search-results.json`
 - Pull 7: fetched 2026-07-30T18:04:41Z — raw `~/.openwiki/connectors/web-search/raw/2026-07-30T18-03-34-547Z/web-search-results.json`
 - Pull 8: fetched 2026-07-31T18:06:36Z — raw `~/.openwiki/connectors/web-search/raw/2026-07-31T18-04-55-956Z/web-search-results.json` — **all 10 queries returned `"error": "fetch failed"`; no usable evidence**
 - Pull 9: fetched 2026-08-01T18:09:15Z — raw `~/.openwiki/connectors/web-search/raw/2026-08-01T18-07-35-101Z/web-search-results.json` — **all 10 queries returned `"error": "fetch failed"`; no usable evidence (gap-fill, not documented at the time)**
 - Pull 10: fetched 2026-08-02T18:07:53Z — raw `~/.openwiki/connectors/web-search/raw/2026-08-02T18-06-12-521Z/web-search-results.json` — **all 10 queries returned `"error": "fetch failed"`; no usable evidence**
 - Pull 11: fetched 2026-08-03T18:08:50Z — raw `~/.openwiki/connectors/web-search/raw/2026-08-03T18-07-31-803Z/web-search-results.json` — **first successful pull after the 3-day outage streak; Tavily back online; see section below**
 - Queries: pulls 1, 2, 4, 5, 6, 7, 8, 9, 10, 11 = 10 queries each; pull 3 = 6 queries (vendor-anchored only)
 - Instance: `web-search-1`
 ---
 ## 2026-08-03 18:08 pull
 Eleventh Tavily pull, run as a stand-alone `openwiki personal --update` source ingest after the `web-search-1` connector's three-day outage streak (pulls 8/9/10 all returned `"error":"fetch failed"`). **Tavily is back online** — all 10 queries returned `answer` text + 2–8 results per query. The material findings are: the first credible **CELLINK × Volumetric "New Lumen X" release** signal on the Robin portfolio (Q3, score 0.819, 3DPrint.com 2026-07-28), a new **3Brain Utrecht Summer School "Human Brain Models" course** vendor-channel post (Q2, score 0.808, LinkedIn 2026-07-29), an independent **CelVivo ClinoStar 2 / Thailand Lab 2026** confirmation from an Indian distributor event page (Q6, score 0.696, labindia-analytical.com 2026-07-31), a **Hermes Agent 0.19.1** GitHub bug report (Q8, score 0.790, NousResearch issues/77000, 2026-08-02), and the first pull where Tavily's **answer text on 3Brain is correct** instead of mis-attributing an EEG-headset paper.
 ### CELLINK × Volumetric release new Lumen X for volumetric bioprinting — source-backed (vendor-anchored, high priority)
 - **3DPrint.com, 2026-07-28:** [CELLINK and Volumetric Release New Lumen X for Lumen X Bioprinting](https://3dprint.com/238627/cellink-volumetric-release-new-lumen-x-bioprinting-la) (score 0.819). Top hit on the Cellink BIO X bioprinter query. Tavily answer text corroborates: "The Cellink BIO X bioprinter is a digital light processing bioprinter set to be showcased at BioMET '26 in Vellore, India, from August 5–7, 2026. It operates with a wavelength of 405 nm and an intensi…" (truncated in the snippet). The Lumen X line is in Robin's portfolio table — this is the first vendor-anchored Lumen X release evidence in any Tavily pull.
 - **Cellink LinkedIn, 2026-07-29:** [Cellink exhibiting at BioMET '26 International Conference on Biomaterials](https://www.linkedin.com/posts/cellink_we-are-excited-to-be-exhibiting-at-biomet) (score 0.762). BioMET '26 Vellore India, 2026-08-05 → 2026-08-07. Cellink vendor channel confirms conference presence (India channel, not Robin's China channel — adjacent).
 - **CELLINK Facebook, 2026-07-28:** [CELLINK — Next stop second international conference](https://www.facebook.com/cellink3d/photos/next-stop-second-international-confere) (score 0.632). Companion post to the BioMET '26 LinkedIn announcement.
 - **CELLINK LinkedIn, 2026-07-28:** [From Star Trek to the Clinic: 3D Bioprinting Facility is Engineering Molecules for Patient](https://www.linkedin.com/posts/cellink_from-star-trek-to-the-clinic-3d-bioprinti) (score 0.560). U. Miami 3D Bioprinting Facility narrative — **re-mention** of the BIO X6 at U. Miami evidence already on `/commitments.md` `cellink-bio-x-gen3-customer-evidence`.
 **Robin relevance:** HIGH. Lumen X is in Robin's portfolio table; the CELLINK × Volumetric release is a credible direct product / partnership announcement on a product Robin actively sells. Per the brief's escalation rule ("CelVivo / 3Brain / Cellink / Femtobiomed news item with no prior row in wiki → write to `commitments.md` with a 1-line 'verify on next vendor check' status"), promoted to a NEW `/commitments.md` item `cellink-volumetric-lumen-x-release`. The BioMET '26 + U. Miami items are companion vendor-channel evidence folded into the existing `cellink-bio-x-gen3-customer-evidence` Notes (no new commitment). The `class-organoid-3d-bioprinting` theme row gets the Lumen X release added as a third vendor-anchored Cellink signal (alongside the BIO X Gen 3 / BIO X6 customer evidence already in the row).
 ### 3Brain Utrecht Summer School Human Brain Models course — source-backed (vendor channel)
 - **3Brain LinkedIn post, 2026-07-29:** [3Brain contributes to Utrecht Summer School course on Human Brain Models](https://www.linkedin.com/posts/3brain_3brain-neuroscience-hdmea-activity-7488166) (score 0.808). Tavily answer text: "The 3Brain CorePlate MEA 2026 is a high-density multi-well electrophysiology platform that supports both focused mechanistic studies and high-throughput screening workflows. It enables scalable, high-resolution electrophysiology for various biological models, including iPSC-derived neuronal or cardi…" — **first Tavily pull where the 3Brain answer is not mis-attribution**. 3Brain contributing an HD-MEA module to a Utrecht Summer School academic course positions CorePlate for the training / academic-channel segment, complementing the conference-booth evidence (ISSCR / ELRIG) already on the existing `3brain-coreplate-2026-conference-positioning` commitment.
 - **3Brain AG company page:** [3Brain AG - We empower researchers to explore intelligent biological networks](https://jp.linkedin.com/company/3brain) (score 0.839). Vendor corporate page anchoring the same HD-MEA messaging.
 - **AIP APL Bioengineering, 2026-07-29:** [Functional human-derived neurospheroids capture cortical-like network complexity](https://pubs.aip.org/aip/apb/article/10/3/036104/3399608/Functional-human-derive) (score 0.339). Application-domain paper on cortical-like networks in human neurospheroids — adjacent evidence for 3Brain-class HD-MEA readouts, not 3Brain-anchored.
 **Robin relevance:** Vendor-channel evidence on the existing `3brain-coreplate-2026-conference-positioning` commitment. The Utrecht Summer School post is the academic / training-channel counterpart to the ISSCR / ELRIG conference-booth evidence captured in pull 7. No new commitment; the existing commitment Notes are extended.
 ### CelVivo ClinoStar 2 + Thailand Lab 2026 (independent confirmation) — source-backed
 - **labindia-analytical.com News & Events, 2026-07-31:** [News & Events](https://stagging.labindia-analytical.com/News) (score 0.696). Top hit on the `labs CelVivo ClinoStar installed base 2026` query. Tavily answer text: "The CelVivo ClinoStar bioreactor is set to be showcased at Thailand Lab 2026, Bangkok, from September 2 to 4, 2026. The ClinoStar 2 model allows precise oxygen regulation and is used in various scient…" (truncated). **Independent confirmation** of two facts from an Indian distributor event page: (a) CelVivo is exhibiting at Thailand Lab 2026 in Bangkok 2026-09-02 → 2026-09-04, (b) `ClinoStar 2` is current product naming with oxygen regulation as a distinguishing feature.
 - The remaining 7 results on this query are Instagram snippets / rotational trophoblast organoids (ScienceDirect S2211124726007151) — same set already documented in pull 7's `celvivo-clinostar-2-nams-demo-2026` commitment; no new Instagram evidence to add.
 **Robin relevance:** Independent corroboration of the ClinoStar 2 product naming and the Thailand Lab 2026 booth — directly relevant to the existing `celvivo-clinostar-2-nams-demo-2026` verification commitment (the prior pull only had Instagram reels and a NexUs Locus demo snippet as evidence; this is the first non-Instagram, named-event confirmation). No new commitment; the existing commitment Notes are extended.
 ### Hermes Agent 0.19.1 GitHub bug report — source-backed (workflow tooling, low priority)
 - **GitHub NousResearch/hermes-agent issues/77000, 2026-08-02:** [[Bug]: Hermes Agent 0.19.1 gpt-5.6-luna + opencode-go](https://github.com/NousResearch/hermes-agent/issues/77000) (score 0.790). Confirms a Hermes Agent 0.19.1 patch release landed on the v0.19.x track — a same-week artifact on the Robin daily-driver stack (the prior HN pull on 2026-08-03 surfaced the v0.20.0 release at item `49159200`). Tavily answer text for the Hermes/M3 lane is **partially fabricated**: "release date of June 1, 2026" — Hermes v0.19 Quicksilver is dated 2026-07-25 (per pull 5 evidence), and there is no June 2026 Hermes release in the documented record. Treat the answer text as untrusted; the underlying GitHub issue URL is the credible signal.
 - **benchlm.ai, 2026-08-01:** [DeepSeek V4 Flash vs MiniMax M3: Benchmarks & Cost](https://benchlm.ai/compare/deepseek-v4-flash-vs-minimax-m3) (score 0.543). Third-party comparison reframing the M3 as "1M context window at $0.30…" — adjacent to `MiniMax-m3` theme row.
 - **unsloth/MiniMax-M3-GGUF, 2026-08-01:** [HuggingFace model card](https://huggingface.co/unsloth/MiniMax-M3-GGUF) (score 0.372). Quantized GGUF artifacts available from unsloth — confirms M3 is on the local-LLM run path. Adjacent to `MiniMax-m3` theme row.
 **Robin relevance:** WORKFLOW TOOLING (low priority). Refreshes `hermes-agent-v0-19-quicksilver` evidence column with the 0.19.1 GitHub bug report and `MiniMax-m3` with the benchlm + unsloth artifacts; does not change Last seen (already 2026-08-03 from the HN pull).
 ### Application-domain cross-anchor: 3D bioprinting + microfluidics convergence
 - **hbsn.amegroups.org, 2026-08-01:** [Spatial architecture and dynamic surveillance: 3D bioprinting and microfluidics converge](https://hbsn.amegroups.org/article/view/157425/html) (score 0.715 on `China cell therapy 3D bioprinting regulation 2026`; score 0.179 on `CellShot CellPick bioprinter 2026`). HepatoBiliary Surgery and Nutrition review covering bioprinted organoids + organ-on-chip intersection — same article surfaces on the China-regulation and the CellShot queries, indicating it is the most-cited adjacent peer-reviewed paper in this window. Cross-anchor between the organ-on-chip and 3D-bioprinting domains; folds into `class-organoid-3d-bioprinting` row evidence without spawning a new theme.
 - **Future Market Insights, 2026-07-29:** [AI-Accelerated Nonclinical Drug Testing Market](https://www.futuremarketinsights.com/reports/ai-accelerated-nonclinical-drug-tes) (score 0.536). Industry report — application-domain only.
 - **openpr.com, 2026-07-29:** [3D Bioprinting Market to Reach USD 6 Billion by 2035](https://www.openpr.com/news/4590634/3d-bioprinting-market-to-reach-usd-6-billion) (score 0.212). Market sizing — adjacent.
 - **FDA, 2026-07-28:** [New Approach Methodologies (NAMs)](https://www.fda.gov/science-research/science-and-research-special-topics/new-app) (score 0.124). **Re-mention** of the FDA NAMs framework first surfaced in pull 7; organ-on-chip included among New Approach Methodologies.
 - **Nature npj Biomedical Innovations, 2026-07-29:** [Challenges and opportunities in generating microvasculature using bioprinting techniques](https://www.nature.com/articles/s44385-026-00100-x) (score 0.180). **Re-mention** of the microvasculature review first surfaced in pull 7.
 ### Agent-memory-architecture cluster — new corroborating source
 - **akitaonrails/ai-memory, GitHub, 2026-07-28:** [docs/research-karpathy-llm-wiki.md](https://github.com/akitaonrails/ai-memory/blob/main/docs/research-karpathy-llm-w) (score 0.601). A third-party research write-up of the Karpathy LLM Wiki pattern — corroborates the `agent-memory-architecture` theme with another independent GitHub-side implementation / write-up. Combined with the prior 14+ distinct sources, the cluster is now 15+ and remains `source-backed`.
 - **Nvidia RTX Spark debut (tech-insider.org, 2026-07-28):** [128 GB Memory, 1 Petaflop AI PC](https://tech-insider.org/nvidia-rtx-spark-ai-pc-launch-2026) (score 0.558). Adjacent hardware — surfaces on the agent-memory query but is local-LLM inference hardware, not agent-memory architecture per se.
 **Robin relevance:** The akitaonrails write-up is a credible GitHub-side corroboration. Refreshes `agent-memory-architecture` Last seen → 2026-08-03 and adds to the evidence column.
 ### CellShot / Femtobiomed / OpenWiki-RAGFlow / Tavily answer-text quality
 - **CellShot / CellPick:** the GEN "Large Bioprinted Tissues Get a Precision Boost" article (already known from pull 6) reappears at 0.056; the **asiaresearchnews "Smart bioink shields delicate neural cells during precision bioprinting"** (2026-08-03, score 0.368) is a new adjacent application-domain article but has no Femtobiomed attribution; the **Pensées cultivated-meat platform at AFPRO** (2026-07-28, score 0.154), **Oxford Academic rbag142 "Three-dimensional bioprinted organoids: advances"** (2026-08-01, score 0.063) are application-domain / market context. **No Femtobiomed CellShot / CellPick / TriArm signal was promoted.**
 - **OpenWiki connectors Tavily RAGFlow 2026:** langchain-ai/openwiki GitHub (2026-08-01, score 0.511) reappears as the lone non-noise result; the lane still returns two Instagram reels. Confirms `openwiki-brand` cluster continuity but does not surface a new openwiki release or a RAGFlow ecosystem shift.
 - **Tavily answer-text quality improvement:** the 3Brain answer text on Q2 was correct for the first time in this 11-pull series — a positive connector-side signal worth flagging. The Cellink / Lumen X answer text on Q3 was vendor-anchored and substantive. The Hermes Agent / M3 answer text on Q8 was partially fabricated ("release date of June 1, 2026") — treat as untrusted. The CelVivo / ClinoStar installed-base Q6 answer text was correct and substantive (Thailand Lab 2026 + ClinoStar 2).
 ### Synthesis result
 - **Three new scope-aligned findings warranting commitment / theme updates:**
  1. **CELLINK × Volumetric release new Lumen X** — first direct Cellink product / partnership release evidence on the Robin portfolio. Promoted to a NEW `/commitments.md` item `cellink-volumetric-lumen-x-release` and to the evidence column of `class-organoid-3d-bioprinting` (third vendor-anchored Cellink signal alongside the existing BIO X Gen 3 / BIO X6 customer evidence).
  2. **3Brain Utrecht Summer School Human Brain Models course** — academic / training-channel evidence on the existing `3brain-coreplate-2026-conference-positioning` verification commitment. No new commitment; existing commitment Notes are extended.
  3. **CelVivo ClinoStar 2 / Thailand Lab 2026** — independent confirmation from an Indian distributor event page on the existing `celvivo-clinostar-2-nams-demo-2026` verification commitment. No new commitment; existing commitment Notes are extended.
 - **Workflow tooling refreshes:** `agent-memory-architecture` Last seen → 2026-08-03 (akitaonrails/ai-memory research doc added). `hermes-agent-v0-19-quicksilver` and `MiniMax-m3` evidence columns refreshed with same-week artifacts (Last seen unchanged at 2026-08-03 from the HN pull).
 - **Tavily answer-text quality:** the 3Brain answer is now correct (first time in 11 pulls); the Cellink Lumen X answer is substantive; the Hermes/M3 answer is partially fabricated ("release date of June 1, 2026") — treat as untrusted. Connector-side quality flag for future pulls: continue to treat Tavily answer text as untrusted; trust the underlying URL + score + published_date.
 - **Operational note for the connector:** Tavily is back online after a 3-day outage streak. The pull 8 / pull 9 / pull 10 advice to check `TAVILY_API_KEY`, Tavily status, and rate-limit posture no longer applies — the lane is functional again. No connector-side configuration change is required.
 - **Coverage:** fetched `2026-08-03T18:08:50.866Z`; 10 queries; raw `~/.openwiki/connectors/web-search/raw/2026-08-03T18-07-31-803Z/web-search-results.json`; instance `web-search-1`.
@@ -3,7 +3,7 @@
 > 数据源: Wiki.js (http://10.10.10.254:3000/graphql) Biokingdom 实例
 > 用途: MiniMax code / Hermes 跨 agent 检索 "Robin 在 Wiki.js 发布了什么"
 > 更新: 自动同步计数 + 手动维护目录
-> 上次同步: **2026-10-21T18:30:03Z** · GraphQL sample (5 orderBy union): **84 unique pages** · ID range 22..1830 · 分布 en=5, zh=79
+> 上次同步: **2026-08-07T11:05:11Z** · GraphQL sample (5 orderBy union): **82 unique pages** · ID range 22..1648 · 分布 en=5, zh=77
 ## Wiki.js 概况
@@ -12,10 +12,10 @@
 | GraphQL API | `http://10.10.10.254:3000/graphql` |
 | Web UI (zh) | `http://10.10.10.254:3000/zh/home` |
 | Web UI (en) | `http://10.10.10.254:3000/en/home` |
-| **估计全页数** | **≥ 1830 (基于 max page id)** — server-side ID gap 显著,实际数大于 sample union |
+| **估计全页数** | **≥ 1648 (基于 max page id)** — server-side ID gap 显著,实际数大于 sample union |
-| Sample union (5 orderBy) | 84 unique pages (GraphQL 返 50 cap) |
+| Sample union (5 orderBy) | 82 unique pages (GraphQL 返 50 cap) |
-| Min / Max ID | 22 / 1830 |
+| Min / Max ID | 22 / 1648 |
-| Locale 分布 (sample) | en=5, zh=79 |
+| Locale 分布 (sample) | en=5, zh=77 |
 | Top-level 路径分布 (前 8, sample) | organoid=50, products=7, literature=5, articles=4, 3brain=2, 3brain-biocam-driver-api-v2-5=1, 3brain-hdmea-system=1, instruments=1 |
 | 主题 | 类器官 / 3D 生物打印 / HD-MEA / CRISPR 类器官精准医疗 |
 | 维护者 | Robin + LDR (literature-reading-queue skill 自动发布) |
@@ -1,9 +1,7 @@
 ---
 type: "Reference"
 title: "Themes"
-description: "Recurring topics, signals, and trends observed across Robin's sources. Index of theme rows with confidence labels and source citations; details live on the linked source and synthesis pages."
+openwiki_generated: true
 tags: [themes, recurring, signals, synthesis, 2026-09-30, 2026-09-29, 2026-09-28, 2026-09-27, 2026-09-26, 2026-09-25, 2026-09-24, 2026-09-20, 2026-09-19, 2026-09-18, 2026-09-17, 2026-09-16, 2026-09-15, 2026-09-14, 2026-09-12, 2026-09-11, 2026-09-10, 2026-09-08, 2026-09-06, 2026-09-05, 2026-09-04, 2026-09-03, cloud-in-a-bottle-8th-cluster-entry, mistral-raises-3b-eur-sovereign-openweight-adjacent, google-jail-for-independent-wikis-openwiki-adjacent, alphagenome-atlas-deepmind-closed-weight-adjacent, libreoffice-no-ai-features-590pt-named-stack-adjacent, fifth-fully-zero-algolia-lane, thirty-first-hn-pull, deepseek-v41-flash-801pt-16th-cluster-adjacent, ai-vendor-business-stack-cluster-10-items, openai-training-toggle-8th-business-stack-entry, openai-proof-stolen-9th-business-stack-entry, openai-unpublished-math-10th-business-stack-entry, cognition-swe-2-coding-agent-adjacent, thirty-second-hn-pull, sixth-fully-zero-algolia-lane, openai-agents-api-11th-business-stack-entry, astra-for-coding-named-stack-adjacent, claude-age-assurance-closed-weight-adjacent, rtk-token-savings-named-stack-adjacent, vault-silence-broken, vault-resumed-after-11d, class-organoid-3d-bioprinting-last-seen-2026-09-11, tomas-2026-hgsoc-parpi-spheroid-organoid, vijakumaran-2026-brain-organoid-ali-oxygen-engineering, flywheel-v4-auto-sink, third-vault-ldr-cluster-2026-09-10-11, thirty-third-hn-pull, first-substring-noise-only-on-4-of-6-algolia-lane, lowest-23-item-dedup-count-streak, first-5-overlap-dedup-since-2026-09-08, openai-agents-rubygems-attack-889pt-off-scope, dario-amodei-we-must-pace-the-frontier-12th-business-stack-candidate, nvidia-is-the-central-bank-of-ai-168pt-adjacent, ilands-ai-agent-spam-78pt-off-scope, apple-ane-reverse-engineering-189pt-off-scope, thirty-fifth-hn-pull, thirty-sixth-hn-pull, ninth-materialization-gap-pull, first-biological-organoid-positive-hit, system-one-models-jev-1728pt-2nd-cluster-candidate, building-linux-gpu-driver-m4-mac-mini-397pt-named-stack-adjacent, mistral-x-mozilla-399pt-adjacent, kival-self-hosted-knowledge-system-5pt-openwiki-adjacent, 4th-consecutive-mac-mini-class-local-llm-adjacency, apple-silicon-canonical-inference-target, thirty-seventh-hn-pull, substring-noise-only-algolia-lane-2-of-6, nyt-fuse-8-children-brain-organoid-28pt-2026-09-17, nature-developmental-xenocortication-2026-09-17, 3rd-brain-organoid-item-in-48h, brain-organoid-cadence-watchlist, thirty-eighth-hn-pull, openjev-405pt-19th-cluster-candidate, bonsai-2-27b-547pt-20th-cluster-candidate, qwen-38-omni-flash-313pt-21st-cluster-candidate, microsoft-ai-scraping-753pt-13th-business-stack-candidate, astra-for-law-560pt-14th-business-stack-candidate, openai-internal-repos-hack-429pt-15th-business-stack-candidate, harness-design-coding-agents-179pt-named-stack-adjacent, 6th-consecutive-clean-zero-celvivo, 4th-consecutive-clean-zero-deepagents, brain-organoid-cadence-ended-2026-09-18, thirty-ninth-hn-pull, substring-noise-only-algolia-lane-3-of-6-zero-on-3-of-6, claude-code-reads-agents-md-702pt-named-stack-adjacent, agents-md-cross-walk-standard-validation, human-brain-two-separate-organs-stanford-523pt-named-stack-adjacent, gpt-6-astra-wwi-cipher-273pt-closed-weight-adjacent, openai-jalapeno-chip-178pt-closed-weight-adjacent, 7th-consecutive-clean-zero-celvivo, 5th-consecutive-clean-zero-deepagents, 3rd-consecutive-clean-zero-openwiki, 2nd-consecutive-fully-zero-3brain, fortieth-hn-pull, substring-noise-only-algolia-lane-2-of-6-zero-on-4-of-6, exfiltrate-your-weights-556pt-openweight-cluster-adjacent, pirate-face-rescues-llm-190pt-openweight-cluster-adjacent, qwen-image-21-299pt-openweight-cluster-adjacent, laya-os-jev-mac-m4-coreml-45pt-5th-consecutive-mac-mini-adjacency, microsoft-director-ai-scraping-179pt-16th-business-stack-candidate, creative-commons-211pt-17th-business-stack-candidate, chatgpt-ad-collector-114pt-18th-business-stack-candidate, step-5-preview-118pt-6th-closed-weight-m3-candidate, millennium-problems-biology-87pt-class-organoid-watchlist, 8th-consecutive-clean-zero-celvivo, 3rd-consecutive-clean-zero-3brain, 4th-consecutive-clean-zero-openwiki, 6th-fully-zero-deepagents-lane, 21-of-22-pulls-deepagents-fully-zero, forty-fourth-hn-pull, claude-discovers-novel-enzyme-system-747pt-7th-closed-weight-m3-candidate, contrastive-language-models-148pt-12th-closed-weight-m3-candidate, whiteboard-yc-w26-39pt-agent-memory-adjacent, owlposting-organoids-alzheimers-1pt-recurring-application-domain, 12th-consecutive-clean-zero-celvivo, 8th-consecutive-fully-zero-openwiki, 10th-fully-zero-deepagents-lane, 25-of-26-pulls-deepagents-fully-zero, forty-fifth-hn-pull, dutch-government-nixos-microsoft-alternative-842pt-independent-substrate-adjacent, opus-55-explainer-videos-372pt-8th-closed-weight-m3-candidate, anthropic-supply-chain-risk-appeals-court-196pt-9th-closed-weight-m3-candidate-23rd-business-stack-candidate, scientific-american-frozen-mouse-brains-1pt-brain-research-adjacency, 13th-consecutive-clean-zero-celvivLine truncated
 timestamp: 2026-09-30T18:00:35Z
 ---
 # Themes
@@ -14,13 +12,18 @@ Index kept narrow by design: only themes that map to Robin's actual work (life-s
 | Topic key | Theme / Signal | First seen | Last seen | Confidence | Sources | Evidence count | Status | Evidence |
 | --- | --- | --- | --- | --- | --- | --- | --- | --- |
-| `class-organoid-3d-bioprinting` | Recurring organoid, 3D bioprinting, and 3D-cell-culture automation coverage; this window adds a 2026-07-28 HN drug-discovery essay (owlposting "Why haven't organoids solved all of drug discovery?", 9 pts), a 2026-07-27 Oxford Academic review on 3D-bioprinted organoids, a 2026-07-22 Sage review on bioprinting-enabled organoids, a 2026-07-27 Pluristyx iPSC + aerospace clinical-grade hepatocyte manufacturing partnership, the first vendor-anchored CelVivo ClinoReactor co-marketing signal (TheWell Bioscience xeno-free workflow pages), the first vendor-anchored Cellink BIO X Gen 3 / BIO X6 signal (Nuclear Mechano-Oncology install + CELLINK LinkedIn U. Miami reference + third-party market report), and the third vendor-anchored Cellink signal — **CELLINK × Volumetric new Lumen X release** (3DPrint.com 2026-07-28) — plus GEN "Large Bioprinted Tissues Get a Precision Boost" (2026-07-29) and MDPI Cells "Rapid Volumetric Bioprinting Coupled with Dynamic Perfusion Enhances Human Hepatic Organoid Toxicity Testing" (2026-07-27) on top of the prior Nature / HN evidence; pull 7 (2026-07-30) adds FDA NAMs framework (2026-07-27, organ-on-chip included among New Approach Methodologies alongside June 2026 cell/gene-therapy draft guidance), Molecular Cancer patient-derived 3D-bioprinted primary liver cancer (Peking Union Medical College Hospital, 2026-07-28), and npj Biomedical Innovations microvasculature bioprinting review (2026-07-29); pull 11 (2026-08-03) re-anchors the HepatoBiliary Surgery and Nutrition "Spatial architecture and dynamic surveillance: 3D bioprinting and microfluidics converge" review (2026-08-01) as the strongest same-week cross-anchor between organ-on-chip and 3D-bioprinting; **flywheel-sync 2026-08-08** adds 3 deep-read papers: Liu 2026 Nat Biomed Eng (shape-conformal porous framework for full-coverage neural organoid e-phys, Rogers Lab — microlattice fabrication rate 5 for Cellink, HD-MEA rate 5 for 3Brain), Miao 2025 Cell v2 (co-differentiation mesoderm+endoderm for vascularized lung/gut organoids — ClinoStar rate 5, organotypic vascularization), Sharma 2026 Cell Stem Cell (vascularized retinal organoid RGC survival — HD-MEA rate 4, CelVivo ClinoStar rate 3 for extending vascular network stability); still mostly application-domain plus three vendor-channel signals (CelVivo+TheWell; Cellink BIO X Gen 3 / BIO X6; Cellink Lumen X) + three literature flywheel-sync application-domain signals (Liu/Miao/Sharma); **2026-08-12 HN pull** adds item `49266068` "AI Is Dead. Organoids Are Alive" (5 pts, Wired, by `Logans_Run`) on lab-grown brain organoids vs silicon AI — application-domain reinforcement of the organoid + neuroscience-in-vitro intersection that the 2026-07-27 Nature biocomputing article (`49071596`) and the 2026-07-28 owlposting drug-discovery essay (`49083799`) already speak to; **2026-08-20 HN pull** adds item `49366519` "Human brain organoids record the passage of time over multiple years" (18 pts top, by `sbulaev`, https://www.nature.com/articles/s41586-026-10877-x) — first new organoid + neuroscience-in-vitro thematic signal since the 2026-08-12 `49266068` Wired `AI Is Dead. Organoids Are Alive` entry, recording that human brain organoids maintained in long-term culture develop signatures of multi-year temporal processing — directly relevant to CelVivo ClinoReactor's long-term stable organoid culture value proposition; cross-walked under `49373812` "Scientists Have Built Miniature Brains That Experience the Passage of Time" (2 pts top, by `geox`, https://www.sciencealert.com/unprecedented-scientists-have-built-miniature-brains-that-experience-the-passage-of-time — Science Alert user-press write-up of the same Nature s41586-026-10877-x paper); **second neural-organoid HN signal in 9 pulls** (after the 2026-07-27 Nature biocomputing article `49071596` and the 2026-08-12 Wired `49266068`), qualifying for Last-seen refresh by the recurrence criterion alone; **2026-08-23/24 git-repo-1 LDR burst (FIRST burst)** adds 5 root-level single-shot entries that **strengthen the class-organoid-3d-bioprinting evidence footprint**: (a) **CelVivo App Note 2026 shear stress ClinoStar vs orbital shaker** — CelVivo-direct competitive-killer document (HepG2/C3A 15d + embedded Caco-2 + brain organoid); (b) **Aiello & Bagni 2025 biorxiv Rotating Chamber brain organoid CFD** — first CFD-quantified RC shear-stress study (< 20 mPa, CelVivo-adjacent); (c) **Ajongbolo 2025 Cells brain organoid + assembloid review** — canonical brain-organoid review (CelVivo ClinoStar-adjacent + 3Brain HD-MEA-adjacent), first comprehensive brain-organoid review since the 2026-07-29 Organoids 2026 review; (d) **Kim 2025 Nat Commun EGaIn liquid-metal 3D MEA** — 3rd next-gen HD-MEA approach alongside Liu 2026 + 3Brain Accura-3D (3Brain-adjacent competitor); (e) **Tian 2025 Nat Commun hiPSC epicardium mTOR maturation** — cardiac-epicardium application-domain expansion (no vendor caLine truncated
+<!-- openwiki: broken internal link [/sources/web-search.md#2026-07-27-1804-pull] heading anchor "2026-07-27-1804-pull" does not exist in "/sources/web-search.md". Fix the href or restore the target, then delete this comment. -->
-| `china-cde-cell-gene-therapy-rules-2026` | China CDE (under NMPA) published technical guidelines defining scope & classification of cell and gene therapy drugs; standardizes CMC planning for Chinese pharma/CDMO/biotech customers | 2026-07-24 | 2026-07-24 | source-backed | web-search | 1 | watchlist | [Tavily: cisema.com 2026-07-24](/sources/web-search.md) |
+| `class-organoid-3d-bioprinting` | Recurring organoid, 3D bioprinting, and 3D-cell-culture automation coverage; this window adds a 2026-07-28 HN drug-discovery essay (owlposting "Why haven't organoids solved all of drug discovery?", 9 pts), a 2026-07-27 Oxford Academic review on 3D-bioprinted organoids, a 2026-07-22 Sage review on bioprinting-enabled organoids, a 2026-07-27 Pluristyx iPSC + aerospace clinical-grade hepatocyte manufacturing partnership, the first vendor-anchored CelVivo ClinoReactor co-marketing signal (TheWell Bioscience xeno-free workflow pages), the first vendor-anchored Cellink BIO X Gen 3 / BIO X6 signal (Nuclear Mechano-Oncology install + CELLINK LinkedIn U. Miami reference + third-party market report), and the third vendor-anchored Cellink signal — **CELLINK × Volumetric new Lumen X release** (3DPrint.com 2026-07-28) — plus GEN "Large Bioprinted Tissues Get a Precision Boost" (2026-07-29) and MDPI Cells "Rapid Volumetric Bioprinting Coupled with Dynamic Perfusion Enhances Human Hepatic Organoid Toxicity Testing" (2026-07-27) on top of the prior Nature / HN evidence; pull 7 (2026-07-30) adds FDA NAMs framework (2026-07-27, organ-on-chip included among New Approach Methodologies alongside June 2026 cell/gene-therapy draft guidance), Molecular Cancer patient-derived 3D-bioprinted primary liver cancer (Peking Union Medical College Hospital, 2026-07-28), and npj Biomedical Innovations microvasculature bioprinting review (2026-07-29); pull 11 (2026-08-03) re-anchors the HepatoBiliary Surgery and Nutrition "Spatial architecture and dynamic surveillance: 3D bioprinting and microfluidics converge" review (2026-08-01) as the strongest same-week cross-anchor between organ-on-chip and 3D-bioprinting; still mostly application-domain plus three vendor-channel signals (CelVivo+TheWell; Cellink BIO X Gen 3 / BIO X6; Cellink Lumen X) | 2026-07-16 | 2026-08-03 | source-backed | hackernews, web-search | 23+ | active | [HN: 49083799 drug-discovery essay 2026-07-28](/sources/hackernews.md#class-organoid-3d-bioprinting-refreshed-this-run); [Tavily: 3D bioprinted organoid reviews + Pluristyx + CelVivo+TheWell 2026-07-27](/sources/web-search.md#2026-07-27-1804-pull); [Tavily: Cellink BIO X Gen 3 / BIO X6 + CN Bio / NASA AVATAR OOC + GEN bioprinting 2026-07-29](/sources/web-search.md#2026-07-29-1803-pull); [Tavily: FDA NAMs + Peking Union 3D-bioprinted liver cancer + npj microvasculature 2026-07-30](/sources/web-search.md#2026-07-30-1804-pull); [Tavily: Cellink × Volumetric new Lumen X + 3Brain Utrecht Summer School + CelVivo ClinoStar 2 / Thailand Lab 2026 + HBSN bioprinting+microfluidics 2026-08-03](/sources/web-search.md#2026-08-03-1808-pull) |
-| `china-order-no-818-clinical-translation` | China's Order No. 818 (effective 2026-05-01) creates an accelerated pathway for advanced biomedical technologies — including cell therapy and 3D bioprinting — towards regulated clinical translation at qualified hospitals after demonstrating safety and preliminary efficacy; the clinical-translation counterpart to the CDE classification item and directly relevant to Robin's Chinese pharma R&D / CDMO / biotech customer base | 2026-07-28 | 2026-07-28 | source-backed | web-search | 1 (+ Tavily synthesis) | watchlist | [Tavily: BetaLife LinkedIn 2026-07 + Roots Analysis re-mention 2026-07-28](/sources/web-search.md) |
+<!-- openwiki: broken internal link [/sources/web-search.md#china-cde-cell-gene-therapy-classification-source-backed] heading anchor "china-cde-cell-gene-therapy-classification-source-backed" does not exist in "/sources/web-search.md". Fix the href or restore the target, then delete this comment. -->
-| `MiniMax-m3` | MiniMax-M3 (1M context multimodal) HuggingFace model card + Twitter launch; the daily-driver inference provider behind every OpenWiki run and most of Robin's agent work; haimaker.ai July 2026 third-party eval ranks models for Hermes Agent usage; MyClaw.ai 2026-07-29 confirms M3 + M2.7 are the operational models for both OpenClaw and Hermes, with M3 supporting multimodal (image, video, music, speech, web search); pull 11 (2026-08-03) adds **unsloth/MiniMax-M3-GGUF** (HuggingFace 2026-08-01) confirming quantized local-LLM run path + **benchlm.ai "DeepSeek V4 Flash vs MiniMax M3: Benchmarks & Cost"** (2026-08-01) reframing M3 as "1M context window at $0.30…"; this 2026-08-03 HN pull surfaces the **MiniMax-H3 launch cluster** (item `49155629` 167pts top-feed ComfyUI Day-0 support with open weights + native audio + 2K video; item `49150583` 8pts "MiniMax-H3 weights are up" on HuggingFace model card; item `49150861` 2pts "Run MiniMax-H3 Locally with SGLang Diffusion on 2× RTX 5090s or 1× RTX Pro 6000" via LMSYS Twitter) — three distinct primary sources on the same day confirming H3 as the next frontier model release after M3; **2026-09-01 HN pull** adds the **12th entry to the open-weight-LLM cluster** — `49524447` "Show HN: Running 104GB Qwen3.8-Flash-Next on 48GB Mac with at ~12 tok/s" (36 pts top + 34 cmts, by `carloslfu` 2026-09-01, https://github.com/carloslfu/slotstream — Show HN local-LLM deployment of Qwen3.8-Flash-Next on a 48GB Mac via the slotstream project); **2026-09-02 HN pull** adds the **13th entry to the open-weight-LLM cluster** — `49529132` "My local model setup on an M4 Pro Mac Mini" (271 pts best + 172 cmts, by `raybb` 2026-09-02, https://lws.io/blog/my-local-model-setup/ — local-LLM setup essay on an Apple Silicon M4 Pro Mac Mini by the same `raybb` author who submitted the 2026-08-23 Qwen 3.8 27B reverse-engineering essay `49407507` 234 pts — direct cross-walk to the prior local-LLM cluster entries + the 2026-09-01 Qwen3.8-Flash-Next-on-Mac 12th entry + the unsloth/MiniMax-M3-GGUF local-LLM run path); **2026-09-03 HN pull** adds the **14th entry to the open-weight-LLM cluster** — `49551760` "K2 Horizon: Frontier Performance, Radically Open" (127 pts top + 32 cmts, by `karimf` 2026-09-03, https://ifm.ai/blog/k2/ — IFM.ai blog post on the K2 Horizon open-weight LLM release; the title explicitly says "Radically Open" matching the cluster's open-weight framing; the **0.25 cmts-to-upvote ratio** indicates substantive technical discussion; the **"K2" naming + "Frontier Performance" + "Radically Open" framing** indicates an open-weight LLM intended to rival established frontier models like Moonshot Kimi K2; **vendor identity (ifm.ai) and weights release status need Tavily verification** — ifm.ai is a less-known indie AI lab than Moonshot / Z.ai / Alibaba / Tencent but the open-weight release framing matches the cluster pattern); **2026-09-04 HN pull** adds the **15th entry to the open-weight-LLM cluster** — `49554520` "Qwen 3.8 27B available on Cerebras at 1500 tokens/s" (660 pts top+best + 218 cmts, by `altertable` 2026-09-04, https://inference-docs.cerebras.ai/models/overview — Cerebras inference docs page on the Qwen 3.8 27B deployment at 1500 tokens/s on Cerebras wafer-scale hardware; the **0.33 cmts-to-upvote ratio** indicates substantive technical discussion of the Cerebras 1500 tokens/s deployment rather than a passive upvote stream; the **660-pt engagement is the highest single open-weight-LLM cluster entry since the 2026-08-26 GLM-5.3-Flash 530 pts** and the **third-highest of the cluster overall** after GLM-5.3-Flash 530 pts + Qwen3.8-Flash-Next release 441 pts; the **Cerebras wafer-scale inference deployment** is the canonical high-throughput-inference anchor for the Qwen family — the prior 2026-08-23 `49407507` Qwen 3.8 27B reverse-engineering essay 234 pts + the 2026-08-25 `49432317` Qwen 3.8-Flash-Next "releasing tomorrow" 244 pts + the 2026-08-26 Qwen3.8-Flash-Next release 441 pts + the 2026-09-01 `49524447` Qwen3.8-Flash-Next on 48GB Mac 36 pts + the 2026-09-02 `49529132` M4-Pro-Mac-Mini local-model-setup 271 pts all sit in the local-LLM deployment lane; the Cerebras 1500 tokens/s deployment adds a new inference-deployment-class anchor to the cluster); the open-weight-LLM cluster now totals **~4,535+ pts across 15 items in 13 pulls over 16 days** — the strongest sustained engagement cluster of the entire 2026-08-07 streak — joining the 2026-08-21 DeepSeek V4 Flash vision 379 pts + 2026-08-19 Unsloth Dynamic 3.0 GGUFs 314 pts + 2026-08-23 GLM-5.3 vs Anthropic/OpenAI 141 pts + 2026-08-23 Qwen 3.8 27B reverse-engineering 234 pts + 2026-08-25 Qwen 3.8-Flash-Next "releasing tomorrow" 244 pts + 2026-08-26 GLM-5.3-Flash 530 pts + 2026-08-26 Qwen3.8-Flash-Next release 441 pts + 2026-08-26 Z.ai Ox Alpha 391 pts + 2026-08-27 Small Models Have Arrived 135 pts + 2026-08-28 GLM-5.3 is now open-weight 268 pts + 2026-08-30 Tencent Hy4 preview 364 Line truncated
+| `china-cde-cell-gene-therapy-rules-2026` | China CDE (under NMPA) published technical guidelines defining scope & classification of cell and gene therapy drugs; standardizes CMC planning for Chinese pharma/CDMO/biotech customers | 2026-07-24 | 2026-07-24 | source-backed | web-search | 1 | watchlist | [Tavily: cisema.com 2026-07-24](/sources/web-search.md#china-cde-cell-gene-therapy-classification-source-backed) |
-| `hermes-agent-v0-19-quicksilver` | Hermes Agent v0.19 "Quicksilver" release (2026-07-25): first-token delay 4.3s → 0.9s, profile routing, live subagent, delivery ledger, 1Password/Bitwarden integration; relevant to Robin's daily-driver stack; MCP 2026-07-28 revision finalization (not backward-compatible) is a related protocol-layer signal; `configuration.md` (2026-07-26) documents the iteration-budget behavior change (April 2026: removed premature 70%/90% warnings, now single wrap-up at 500/500 with grace call) and `features/api-server.md` (2026-07-27) documents new `/v1/runs/{run_id}/stop` + `/approval` endpoints with MiniMax-M3 as the documented default model; pull 7 (2026-07-30) re-anchors `api-server.md` with a new per-profile `API_SERVER_KEY` breaking-change warning and a runs API for long-form sessions, and adds a third-party Hermes Atlas "State of Hermes Agent — July 2026" report; this 2026-08-03 HN pull surfaces **Hermes Agent v0.20.0** (item `49159200`, NousResearch GitHub releases tag `v2026.8.3`, 1pt on HN day-of — the next major version after v0.19 Quicksilver); pull 11 (2026-08-03) adds a **Hermes Agent 0.19.1 GitHub bug report** (NousResearch issues/77000, 2026-08-02, score 0.790, "gpt-5.6-luna + opencode-go") confirming patch-version activity on the v0.19.x track between the v0.19 Quicksilver release and the v0.20.0 release; Tavily answer text on the Hermes/M3 lane was partially fabricated ("release date of June 1, 2026") and should be ignored — the underlying GitHub issue URL is the credible signal; **2026-09-06 HN pull** adds item `49582000` "Cloud in a Bottle: making self-hosting accessible to everyone" (559 pts top+best + 277 cmts, by `zplizzi` 2026-09-05, https://cloudinabottle.org/blog/launch-post — **8th entry in the self-hosted-agentic-substrate cluster** of the 2026-08-07 streak) — a YC-grade launch of an open-source self-hosting product (cloudinabottle.org) that ships a single-binary containerized stack targeted at "making self-hosting accessible to everyone"; the **559-pt top+best + 277-cmt engagement is the highest single cluster entry** of the entire self-hosted-agentic-substrate cluster, surpassing the 2026-08-13 DeepSeek Harness 422 pts (prior top entry) — 0.50 cmts-to-upvote ratio indicates substantive engineering discussion of the Cloud in a Bottle launch; the **Cloud-in-a-Bottle single-binary self-hosting framing** directly cross-walks to Robin's OpenWiki + Hermes + Obsidian-vault stack (a single binary that lets non-technical users stand up the same kind of self-hosted substrate that Robin runs at `/home/ldw/workspace`); the cluster engagement breakdown: DeepSeek Harness 422 + machine0 19 + OneCLI 21 + self-hosted agentic software factory 16 + Munder Difflin 192 + "What Is a Harness?" 121 + LangChain deepagents 1 + **Cloud in a Bottle 559** = **~1,351+ pts across 8 entries / 15 days** — the cluster is now the **highest single-engagement sustained cluster** in the 2026-08-07 streak after the open-weight-LLM cluster's 15 items / ~4,535+ pts; **2026-09-19 HN pull** adds **item `49760187` "Claude Code now reads AGENTS.md if there is no Claude.md"** (702 pts best + 262 cmts, by `theanonymousone` 2026-09-19, https://github.com/anthropics/claude-code/issues/12345 — **HIGHLY NAMED-STACK-ADJACENT** because the **AGENTS.md cross-walk standard** that Anthropic's Claude Code now reads is the same standard Codex CLI uses on Robin's named daily-driver stack — Codex CLI is on Robin's named coding-agent stack (Hermes / MiniMax-M3+H3 / OpenWiki / RAGFlow / NocoDB / SeaFile / Codex CLI); the **702-pt best + 262-cmt engagement is the 3rd-highest engagement of the 2026-09-19 pull** + the **highest-engagement AGENTS.md cross-walk standard validation signal of the 2026-08-07 streak since the 2026-08-20 `49367350` "Feature Request: Support AGENTS.md" 340 pts + 212 cmts feature-request issue** that asked Anthropic to natively support the `AGENTS.md` standard; the 2026-09-19 `49760187` item confirms Anthropic has shipped AGENTS.md support in Claude Code; the **AGENTS.md standard cross-walk** now has **2 high-engagement HN signals on Anthropic Claude Code** + the **OpenWiki ROOT_SYSTEM_POLICY** anchor at "Repository /AGENTS.md and /CLAUDE.md files are instructions for repository code agents, not local-wiki instructions." + the **Hermes Agent skill-file pattern** + the **Codex CLI skill-file pattern** + the **OpenClaw skill folder** + the **4 OpenWiki bridge skills** documented in `/sources/OpenWiki速查手册.md` §5 — **a real emerging cross-vendor repository-level agent-instruction standard cross-walk**; **adjacent-not-promoted per scope** because (a) Claude Code is not on Robin's named daily-driver stack (Codex CLI is the named coding-agent), (b) the engagement is significant but the entry is a Claude Code feature-ship rather than a Hermes Agent / Codex CLI / OpenWiki release, (c) the row's refresh trigger is a direct Hermes / Codex CLI / OpenWiki release rather than a tLine truncated
+| `china-order-no-818-clinical-translation` | China's Order No. 818 (effective 2026-05-01) creates an accelerated pathway for advanced biomedical technologies — including cell therapy and 3D bioprinting — towards regulated clinical translation at qualified hospitals after demonstrating safety and preliminary efficacy; the clinical-translation counterpart to the CDE classification item and directly relevant to Robin's Chinese pharma R&D / CDMO / biotech customer base | 2026-07-28 | 2026-07-28 | source-backed | web-search | 1 (+ Tavily synthesis) | watchlist | [Tavily: BetaLife LinkedIn 2026-07 + Roots Analysis re-mention 2026-07-28](/sources/web-search.md#china-order-no-818--accelerated-clinical-translation-pathway--source-backed) |
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 | `MiniMax-m3` | MiniMax-M3 (1M context multimodal) HuggingFace model card + Twitter launch; the daily-driver inference provider behind every OpenWiki run and most of Robin's agent work; haimaker.ai July 2026 third-party eval ranks models for Hermes Agent usage; MyClaw.ai 2026-07-29 confirms M3 + M2.7 are the operational models for both OpenClaw and Hermes, with M3 supporting multimodal (image, video, music, speech, web search); pull 11 (2026-08-03) adds **unsloth/MiniMax-M3-GGUF** (HuggingFace 2026-08-01) confirming quantized local-LLM run path + **benchlm.ai "DeepSeek V4 Flash vs MiniMax M3: Benchmarks & Cost"** (2026-08-01) reframing M3 as "1M context window at $0.30…"; this 2026-08-03 HN pull surfaces the **MiniMax-H3 launch cluster** (item `49155629` 167pts top-feed ComfyUI Day-0 support with open weights + native audio + 2K video; item `49150583` 8pts "MiniMax-H3 weights are up" on HuggingFace model card; item `49150861` 2pts "Run MiniMax-H3 Locally with SGLang Diffusion on 2× RTX 5090s or 1× RTX Pro 6000" via LMSYS Twitter) — three distinct primary sources on the same day confirming H3 as the next frontier model release after M3 | 2026-07-16 | 2026-08-03 | source-backed | hackernews, web-search | 8+ | active | [HN: M3 model cluster (huggingface + twitter)](/sources/hackernews.md#MiniMax-m3-watchlist); [Tavily: Hermes Agent best-models eval](/sources/web-search.md#hermes-agent-best-models-eval-source-backed-workflow-tooling-low-priority); [Tavily: MyClaw OpenClaw vs MiniMax Agent 2026-07-29](/sources/web-search.md#2026-07-29-1803-pull); [Tavily: unsloth/MiniMax-M3-GGUF + BenchLM M3 vs DeepSeek V4 Flash 2026-08-03](/sources/web-search.md#2026-08-03-1808-pull); [HN: MiniMax-H3 launch cluster 2026-08-03](/sources/hackernews.md#MiniMax-h3-launch-cluster-refreshed-this-run) |
 | `hermes-agent-v0-19-quicksilver` | Hermes Agent v0.19 "Quicksilver" release (2026-07-25): first-token delay 4.3s → 0.9s, profile routing, live subagent, delivery ledger, 1Password/Bitwarden integration; relevant to Robin's daily-driver stack; MCP 2026-07-28 revision finalization (not backward-compatible) is a related protocol-layer signal; `configuration.md` (2026-07-26) documents the iteration-budget behavior change (April 2026: removed premature 70%/90% warnings, now single wrap-up at 500/500 with grace call) and `features/api-server.md` (2026-07-27) documents new `/v1/runs/{run_id}/stop` + `/approval` endpoints with MiniMax-M3 as the documented default model; pull 7 (2026-07-30) re-anchors `api-server.md` with a new per-profile `API_SERVER_KEY` breaking-change warning and a runs API for long-form sessions, and adds a third-party Hermes Atlas "State of Hermes Agent — July 2026" report; this 2026-08-03 HN pull surfaces **Hermes Agent v0.20.0** (item `49159200`, NousResearch GitHub releases tag `v2026.8.3`, 1pt on HN day-of — the next major version after v0.19 Quicksilver); pull 11 (2026-08-03) adds a **Hermes Agent 0.19.1 GitHub bug report** (NousResearch issues/77000, 2026-08-02, score 0.790, "gpt-5.6-luna + opencode-go") confirming patch-version activity on the v0.19.x track between the v0.19 Quicksilver release and the v0.20.0 release; Tavily answer text on the Hermes/M3 lane was partially fabricated ("release date of June 1, 2026") and should be ignored — the underlying GitHub issue URL is the credible signal | 2026-07-25 | 2026-08-03 | source-backed | hackernews, web-search | 10 | active | [Tavily: Hermes v0.19 Quicksilver + MCP revision 2026-07-27](/sources/web-search.md#hermes-agent-v019-quicksilver-release--source-backed-workflow-tooling-low-priority); [Tavily: hermes-agent configuration.md + api-server.md + MyClaw 2026-07-29](/sources/web-search.md#2026-07-29-1803-pull); [Tavily: api-server.md API_SERVER_KEY break + Hermes Atlas state report 2026-07-30](/sources/web-search.md#2026-07-30-1804-pull); [Tavily: Hermes Agent 0.19.1 GitHub bug report 2026-08-03](/sources/web-search.md#2026-08-03-1808-pull); [HN: Hermes Agent v0.20.0 release 2026-08-03](/sources/hackernews.md#hermes-agent-v0200-release-refreshed-this-run) |
 | `openwiki-brand` | `langchain-ai/openwiki` (96 pts) — same product family as Robin's OpenWiki; high-engagement on HN | 2026-07-16 | 2026-07-16 | source-backed | hackernews | 1 (+ 2 adjacent wrappers) | watchlist | [HN: openwiki cluster](/sources/hackernews.md#openwiki-brand-signal) |
-| `agent-memory-architecture` | Shared agent-memory architecture using Karpathy's LLM Wiki + Google's Open Knowledge Format (OKF) + MCP — let "every Local AI share ONE permanent memory"; this 2026-07-29 Tavily pull adds four more corroborated sources (Hackernoon Moorcheh.ai "Agent Memory Has a Lock-In Problem. Open Formats Are How We Fix It." with diffability / reviewability / auditability framing; Towards Data Science "Usage-Reinforced Decay Engine for AI Agent Memory" using Ebbinghaus forgetting curve; The Register / MinIO AIStor Memory for long-running multi-step workflows; HPCwire Exabase M-1 BEAM benchmark numbers 76.9% / 75.0% / 68.0% at 100K/1M/10M tokens) on top of the prior HN + Tavily sources; the Hackernoon piece is the strongest OpenWiki-aligning source yet; pull 7 (2026-07-30) adds arXiv 2607.24759v1 "A Templated Substrate for Heterogeneous Collaborative" + rohitg00 LLM Wiki v2 (extending Karpathy's LLM Wiki pattern with lessons from building agentmemory) + Pi `@zosmaai/pi-llm-wiki` package + MinIO AIStor Memory (HPCwire 2026-07-29 + SiliconANGLE 2026-07-30); pull 11 (2026-08-03) adds **akitaonrails/ai-memory `docs/research-karpathy-llm-wiki.md`** (GitHub 2026-07-28, score 0.601) — a third-party research write-up of the Karpathy LLM Wiki pattern — bringing the cluster to 15+ distinct sources; **2026-08-13 HN pull** adds item `49286073` "Show HN: MCP Memory – Fast Agent Memory Using Google's OKF and SQLite FTS5" (46 pts, 22 cmts, github.com/fellowgeek/mcp-memory) — **the first HN item since the 2026-07-16 `langchain-ai/openwiki` brand signal to explicitly name Google's OKF frontmatter** (the same schema OpenWiki uses at `/index.md` frontmatter `okf_version: "0.1"` and across every concept page's per-page frontmatter), paired with an MCP-server delivery channel that touches the 2026-07-28 MCP-protocol revision watchlist already feeding [`hermes-agent-v0-19-quicksilver`](/sources/hackernews.md) Evidence cell — direct corroboration of the OKF+memory schema pattern rather than a new theme; **2026-08-31 HN pull** adds item `49511007` "Launch HN: Almanac (YC S26) – AI that knows your company" (21 pts top+best + 22 cmts, https://usealmanac.com/ — YC S26 launch) — **first shipped-product evidence of the wikis-as-agent-memory-substrate pattern** (every prior source on the row is either a substrate-pattern essay, an open-source library, a research write-up, or a benchmark; Almanac is the first YC S26 launch that operationalizes the pattern as a hosted product with personal + company wikis + cross-source connectors (Gmail, Calendar, Granola, PostHog) + pre-compiled knowledge layer + long-horizon task tracking + proactive background-worker agents — the same architectural pattern as OpenWiki's 7-connector cron pipeline + OKF frontmatter + `/commitments.md` long-horizon tracking + `~/.openwiki/wiki` local markdown substrate); surfaced via Algolia `organoid` + `3Brain` substring-noise duplicate (the word "brain" appears 4+ times in the launch text). Refresh anchor: 2026-08-13 → 2026-08-31; Evidence count 16+ → 17+; row confidence stays `source-backed` (the row was already corroborated by 16+ sources before the Almanac refresh; the new refresh adds shipped-product evidence without changing the row's structural framing); **2026-09-02 HN pull** does not surface any new OKF / MCP Memory / Karpathy LLM Wiki / Almanac-like canonical artifact — `49528310` Compilr.dev Studio "A project brain AI agents write to and people read" (2 pts + 1 cmt, surfaced via Algolia `3Brain` substring-noise duplicate) is adjacent-not-promoted per scope because engagement is well below the 21-pt Almanac refresh trigger + it is a specific agent product rather than a substrate-pattern artifact; **2026-09-19 HN pull** adds a **cross-walk signal to the AGENTS.md repository-level agent-instruction standard** — **item `49760187` "Claude Code now reads AGENTS.md if there is no Claude.md"** (702 pts best + 262 cmts, by `theanonymousone` 2026-09-19, https://github.com/anthropics/claude-code/issues/12345 — **HIGHLY NAMED-STACK-ADJACENT** because the AGENTS.md cross-walk standard that Anthropic's Claude Code now reads is the same standard Codex CLI uses on Robin's named daily-driver stack — Codex CLI is on Robin's named coding-agent stack (Hermes / MiniMax-M3+H3 / OpenWiki / RAGFlow / NocoDB / SeaFile / Codex CLI); the **702-pt best + 262-cmt engagement is the 3rd-highest engagement of the 2026-09-19 pull** + the **highest-engagement AGENTS.md cross-walk standard validation signal of the 2026-08-07 streak since the 2026-08-20 `49367350` "Feature Request: Support AGENTS.md" 340 pts + 212 cmts feature-request issue** that asked Anthropic to natively support the `AGENTS.md` standard; the 2026-09-19 `49760187` item confirms Anthropic has shipped AGENTS.md support in Claude Code; the AGENTS.md standard cross-walk now has 2 high-engagement HN signals + the OpenWiki ROOT_SYSTEM_POLICY anchor + the Hermes Agent skill-file paLine truncated
+| `agent-memory-architecture` | Shared agent-memory architecture using Karpathy's LLM Wiki + Google's Open Knowledge Format (OKF) + MCP — let "every Local AI share ONE permanent memory"; this 2026-07-29 Tavily pull adds four more corroborated sources (Hackernoon Moorcheh.ai "Agent Memory Has a Lock-In Problem. Open Formats Are How We Fix It." with diffability / reviewability / auditability framing; Towards Data Science "Usage-Reinforced Decay Engine for AI Agent Memory" using Ebbinghaus forgetting curve; The Register / MinIO AIStor Memory for long-running multi-step workflows; HPCwire Exabase M-1 BEAM benchmark numbers 76.9% / 75.0% / 68.0% at 100K/1M/10M tokens) on top of the prior HN + Tavily sources; the Hackernoon piece is the strongest OpenWiki-aligning source yet; pull 7 (2026-07-30) adds arXiv 2607.24759v1 "A Templated Substrate for Heterogeneous Collaborative" + rohitg00 LLM Wiki v2 (extending Karpathy's LLM Wiki pattern with lessons from building agentmemory) + Pi `@zosmaai/pi-llm-wiki` package + MinIO AIStor Memory (HPCwire 2026-07-29 + SiliconANGLE 2026-07-30); pull 11 (2026-08-03) adds **akitaonrails/ai-memory `docs/research-karpathy-llm-wiki.md`** (GitHub 2026-07-28, score 0.601) — a third-party research write-up of the Karpathy LLM Wiki pattern — bringing the cluster to 15+ distinct sources | 2026-07-26 | 2026-08-03 | source-backed | hackernews, web-search | 15+ | active | [HN: 49059959, 49059889, 49060215](/sources/hackernews.md#agent-memory-architecture-watchlist--new); [Tavily: LLM Wiki + OKF cluster 2026-07-28](/sources/web-search.md#llm-wiki--okf--shared-agent-memory-cluster--source-backed-workflow-tooling-low-priority); [Tavily: Moorcheh.ai + TDS + MinIO + Exabase cluster 2026-07-29](/sources/web-search.md#2026-07-29-1803-pull); [Tavily: arXiv 2607.24759v1 + LLM Wiki v2 + Pi pi-llm-wiki + MinIO AIStor 2026-07-30](/sources/web-search.md#2026-07-30-1804-pull); [Tavily: akitaonrails/ai-memory research write-up 2026-08-03](/sources/web-search.md#2026-08-03-1808-pull) |
 ## Notes
@@ -31,7 +34,3 @@ Index kept narrow by design: only themes that map to Robin's actual work (life-s
 - Topic rows like `coding-agent-tooling`, `context-engineering-claude5`, `ai-safety-debate`, `open-weight-ai`, `computer-use-agents`, `codex-openai`, `llm-on-old-hardware`, `local-LLM-stream` are deliberately absent here. Their evidence lives in `/sources/hackernews.md` for traceability but they do not earn a `themes.md` row.
 - Vendor brand signal: CelVivo, 3Brain, Cellink, ClinoStar, ClinoReactor, Femtobiomed CellShot/CellPick/TriArm still have **no material Hacker News footprint** (see `/sources/hackernews.md` query-hit table). The web-search connector (Tavily) is the better lane for these — see `/sources/web-search.md` for the first pull on 2026-07-26.
 - **Five-theme synthesis layer (per `~/.openwiki/INSTRUCTIONS.md` user scope):** `/themes/01-organoid-equipment.md` (CelVivo / 3Brain), `/themes/02-bioprinting.md` (Cellink / BIONOVA), `/themes/03-ai-agents.md` (Hermes / Codex / MiniMax code / OpenWiki), `/themes/04-local-llm.md` (Ollama / bge-reranker / RAGFlow / LM Studio), `/themes/05-robin-research.md` (vault deep reads + sales ammunition + CRM + work rhythm). All 5 are generated as of the 2026-08-07 update; this row index (above) is the recurring-signal index, distinct from the 5-theme synthesis layer.
 s.md` (Hermes / Codex / MiniMax code / OpenWiki), `/themes/04-local-llm.md` (Ollama / bge-reranker / RAGFlow / LM Studio), `/themes/05-robin-research.md` (vault deep reads + sales ammunition + CRM + work rhythm). All 5 are generated as of the 2026-08-07 update; this row index (above) is the recurring-signal index, distinct from the 5-theme synthesis layer.
 eme synthesis layer.
 istinct from the 5-theme synthesis layer.
 istinct from the 5-theme synthesis layer.
@@ -59,10 +59,6 @@ The state diagram shows the canonical CelVivo → 3Brain workflow: 3D suspension
 - **Whitepaper: "Breaking the Bias" (2026, 16 pp)** — CelVivo's official vendor narrative on brain organoid long-term culture. Key data: ~110 day / 8 mm diameter brain organoid (Univ. Groningen, Trombetta-Lima); sc-RNA-seq 17,738 cells at Day 90 (Univ. Lausanne, Bagni); Day 30/45 dorsal forebrain comparison vs orbital shaker (Drexel, Qiang); hiPSC → cortical organoid + Omicron BA.5 (QIMR Berghofer, Stewart 2022). 4 patents: WO 2021/001472, WO 2021/245117, WO 2022/008292, WO 2022/144461. Full synthesis at [`/sources/literature-celvivo-brain-whitepaper-2026.md`](/sources/literature-celvivo-brain-whitepaper-2026.md).
 - **Bosnjakovic 2025 bioRxiv (PAH HepG2 3D spheroid, ClinoStar dynamic culture)** — 21-day maturation + 24h/96h BaP/BBF exposure; **4 metabolic markers (phenylalanine, TCA intermediates, GSH depletion, sphingolipid dysregulation) only appear in 3D, completely invisible in 2D**. Sales ammunition: "your 2D model is missing 100% of environmental toxicology early signals". Synthesis at [`/sources/literature-cel-bosnjakovic-2025-pah-deepread.md`](/sources/literature-cel-bosnjakovic-2025-pah-deepread.md).
 - **Miao 2025 Cell v2 (co-differentiation mesoderm + endoderm, vascularized lung/gut organoids, ClinoStar rotating culture)** — single 3D EB co-induction strategy yields **vHLPO with 7% ECs vs traditional HLPO 0%**, organ-specific endothelium + mesenchyme scRNA-seq validation, in-vivo functional integration with host circulation, FOXF1 mutation ACDMPV dual-pathology disease modeling. Product relevance: CelVivo ClinoStar rating 5 (co-differentiation depends on 3D EB self-organization in low-shear rotating culture — ClinoStar is the canonical hardware), HD-MEA rating 4, 3D bioprinting rating 3, patient-derived organoid drug screening rating 5. Synthesis at [`/sources/literature-miao-2025-cell-vascularization-v2-deepread.md`](/sources/literature-miao-2025-cell-vascularization-v2-deepread.md).
 - **Liu 2026 Nat Biomed Eng (shape-conformal porous framework for neural organoid e-phys, Rogers Lab)** — CelVivo ClinoStar rating 4 (organoid culture downstream of the shape-conformal framework; long-term maturation + functional readout is the canonical ClinoStar → HD-MEA workflow). Synthesis at [`/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md`](/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md). See 3Brain evidence for the HD-MEA read side.
 - **Quintard 2024 Nat Commun (microfluidic platform integrating functional vascularized organoids-on-chip, 2026-08-16)** — CelVivo ClinoStar rating 3 (upstream workflow: BVO differentiation day 0-15 needs rotating-wall suspension culture; ClinoStar is the canonical hardware for this stage; the paper's day 15 → chip-on-board handoff is the canonical CelVivo → organ-on-chip workflow). Mimetas OrganoPlate rating 4 (direct Phaseguide-based vascularized / kidney / intestine organ-on-chip competitor — Robin's portfolio does not currently cover Mimetas but the platform represents a candidate cross-sell if Robin's customers ask "where do I run my CelVivo-matured organoids in a vascularized microenvironment?"). Emulate Organ-Chip rating 3 (Colon-Intestine-Liver platform companion). 10 通道并行微流控芯片 + hiPSC-BVO + 间充质球体 + 胰岛球体 + 肺类器官 跨类器官验证; 血管层级化 37 µm 上游动脉-静脉 + 8 µm BVO 毛细管; 壁剪切 27-2000 s⁻¹ 完美匹配人体毛细血管生理范围 50-1900 s⁻¹. 4-commit LDR cycle 2026-08-16 (commits `0fc8db24` → `290e9635` → `24c713de` → `4073abf4` — last commit deleted the 3Brain reference per the SOP "硬门槛合规修正" cleanup rule because Quintard is organ-on-chip territory rather than 3Brain territory). Wiki IDs 1719/1720/1722, NocoDB Id 3297, DOI 10.1038/s41467-024-45710-4. Sales ammunition: "你的类器官前段培养到 day 15, 后段血管化怎么接? 我们的 CelVivo ClinoStar 提供 day 0-15 金标准旋转培养, 后接 Quintard 2024 微流控芯片做 30 天功能性血管化灌注". Customer entry: 药企临床前 (vascularized drug screening) + 微流控 organ-on-chip 平台集成商 (Mimetas / Emulate channel partners) + academic PI (vascular development / diabetes). Vault path: `obsidian-vault/Literature/Deep-Reads/Organoid/quintard_2024_vasorganoid_chip.md` (189 lines + 6 真图).
 - **Liang 2026 Sci Rep (mouse liver organoid 3-轨道 + fibrosis modeling, 2026-08-12)** — CelVivo ClinoStar rating 4 (P1-P10 长程扩增对应旋转培养 30+ 天无剪切; single DAPT only sustains P5, DAPT+Dex 协同才实现 P10 稳定成熟), CelVivo ClinoReactor rating 4 (单组织 3 轨道 [Hep/Cho/HSC] 分通道灌流; TGFβ 时间程序精确切换实现纤维化激活模型), CelVivo PhaseHolographic 成像 rating 3 (3D 球体直径/CV 实时 QC), 3Brain HD-MEA rating 3 (肝-神经互作延伸场景). 3 轨道 from 单份小鼠肝组织 (密度梯度离心 + 差速贴壁) → DAPT+Dex P1-P10 长程稳定成熟 (ALB / PAS / LDL / CYP 跨代保持) → TGFβ 5-7 天激活 qHSC → aHSC (Acta2/Col1a1 上调) → aHSC 共培养诱导 Hep-Orgs EMT (Snail/Twist/Vimentin ↑; ALB/CK8 ↓; Lgr5/EpCAM ↓; Ki67 ↓) = 体外肝纤维化模型. Wiki.js Id=1716, NocoDB Id=770, PMID 41857098. Page 946 9 项 SOP 重写版 + page 934 修齐 标杆 (4-commit LDR cycle 2026-08-12). **First deep-read whose `related:` field already names `[[MOC-类器官与3D培养]]`** on the day of publication — confirms MOC pattern in active use on real deep-reads. Vault path: `04-Literature/Deep-Reads/Liver/2026-08-12_Liang_2026_SciRep_liver_organoid_fibrosis_platform.md` (170 lines). Sales ammunition: "你的肝类器官只能短期培养? DAPT+Dex P1-P10 稳定成熟 + 单组织 3 轨道 + 14 天纤维化模型 — ClinoStar + ClinoReactor 一站搞定". Customer entry: 药企临床前 (抗纤维化药筛 14+ 天 3D 多细胞模型) + 临床肝活检中心 (1-2 mg 组织 → 3 周药敏 → ClinoReactor 6 通道一次测 6 药). Tracks in `/commitments.md` as `liang-2026-celvivo-clinostar-positioning`.
 - **Sales ammunition kit (CelVivo pricing + 8 Protocols + 5 app notes + 5 brand/whitepapers)** — Demo kit `10005-6` lists at €300 (Global Distributor Price, with special discount). 8 ClinoReactor Protocols cover prepare / media change / gardening / plate config / rotation-speed / alginate embed / VitroGel embed. 5 application notes cover HepG2/C3A liver, FTC-133 thyroid, NCI-H69V SCLC, TNBC, ClinoStar vs Orbital Shaker. Synthesis at [`/sources/sales-ammunition.md`](/sources/sales-ammunition.md).
 - **260528_CS vs OS app note (2026-07-17 deep read)** — ClinoStar vs Orbital Shaker shear-stress comparison for long-term 3D construct performance; ClinoStar has lower shear + long-term growth + better consistency. This is the **vs-competitor killer document** for "why not use an orbital shaker" customer questions.
 - **111_Planimetry app note (2026-07-17 deep read)** — Planimetry measurements of spheroids in ClinoReactor using FIJI (open-source). Standard answer for "how to quantify spheroids".
@@ -70,8 +66,6 @@ The state diagram shows the canonical CelVivo → 3Brain workflow: 3D suspension
 ### 3Brain evidence
 - **Raji 2026 Mol Psychiatry (hMOs + 3Brain HD-MEA, 2026-07-27 deep read)** — WNT-modulated human midbrain organoids + 3Brain BioCAM DupleX + Accura-3D (4096 electrodes) + BrainWave 5. **TH+ 58% at 12 weeks** (vs 2D 18%, 3D static 32%). DA release 76 pg/mL (vs 2D 12, 3D static 28). α-synuclein PFF → DA neurons -35% / TH -40% / DA release -45% — establishes the **PD drug screening platform**. Shear-stress 15x lower than orbital shaking (0.13 dyn/cm² vs 2.03 dyn/cm²). Synthesis at [`/sources/literature-raji-2026-deepread.md`](/sources/literature-raji-2026-deepread.md).
 - **Liu 2026 Nat Biomed Eng (shape-conformal porous framework, full-coverage neural organoid e-phys, Rogers Lab)** — HD-MEA rating 5: **3000-8000 channels per organoid vs traditional MEA 200-1000 (10-50× improvement), >90% surface coverage vs 5-15%, weeks-long stable recording + bi-directional electrical + optogenetic stimulation, epilepsy + AD disease modeling**. The framework is the **direct next-generation design reference** for 3Brain's current 4096-electrode Accura-3D; Robin should sell Accura-3D as the existing best-in-class and Liu 2026 as the forward-looking 3D-coverage direction. Synthesis at [`/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md`](/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md). Tracks as `liu-2026-hd-mea-roadmap-implication` commitment (verify with 3Brain whether flexible-electronics / shape-conformal framework is on their roadmap).
 - **Sharma 2026 Cell Stem Cell (vascularized retinal organoids, RGC survival)** — HD-MEA rating 4: paper uses 60-channel MCS MEA2100-Lite; 3Brain HD-MEA is same-generation HD technology, technical route is transferable. The W31 ON/OFF/ON-OFF light-response recording paradigm is the kind of long-duration, multi-class recording where HD spatial resolution matters most. CelVivo ClinoStar rating 3 (vascular network regresses in static culture → ClinoStar low-shear route candidate). W18 RGC yield **18.2% vs ctrl-RO 1.21% (15× improvement)** through C3 endothelial monolayer integration. Synthesis at [`/sources/literature-sharma-2026-cell-stem-cell-vascularized-retinal-organoid-rgc-deepread.md`](/sources/literature-sharma-2026-cell-stem-cell-vascularized-retinal-organoid-rgc-deepread.md).
 - **3Brain Sample Holder Set / PressNet (UK GB2624872)** — Mechanical net-press device for CorePlate 1W/6W; load force 250–1250 µN. Recorded 2026-07-07 (untracked in vault). Carryover evidence in [`/sources/git-repo.md`](/sources/git-repo.md) Notable entities.
 - **3Brain end-customer dossiers** — 11+ dossiers under `03-Resources/End-Customers/` covering 神经所 (上海), 北京大学, 北京天坛医院, 浙大一附院, 中科院昆明动物所, 西南医科大学, 贵州医科大学, plus TCM accounts at 云南中医药大学 and 天津创新中药. Listed in [`/sources/git-repo.md`](/sources/git-repo.md) Notable entities.
 - **Vendor-channel strand (Tavily 2026-07-30 → 2026-08-03)** — 3Brain's official website + LinkedIn (booth 412 at ISSCR 2026; booth 4 at ELRIG Drug Discovery; Utrecht Summer School "Human Brain Models" course 2026-07-29). Tracks in `/commitments.md` as `3brain-coreplate-2026-conference-positioning` (verify which conference posts are current and pull application notes).
@@ -79,8 +73,6 @@ The state diagram shows the canonical CelVivo → 3Brain workflow: 3D suspension
 ## Cross-vendor workflow links
 - **CelVivo + 3Brain joint workflow** (from Raji 2026): hMOs are cultured in a **bioreactor** (CelVivo-class, low-shear rotating-wall) for 12 weeks; transplanted to **3Brain Accura-3D** (4096-electrode HD-MEA chip) for 24h spike-train recording via BrainWave 5. Two pieces of hardware from two vendors compose the **PD drug screening platform** Robin sells.
 - **CelVivo + 3Brain next-gen workflow** (from Liu 2026): the shape-conformal porous framework (Rogers Lab, next-gen HD-MEA design) records 3000-8000 channels per organoid vs current 4096 — **forward-looking direction** for the CelVivo → 3Brain pipeline. Track in `/commitments.md` as `liu-2026-hd-mea-roadmap-implication`.
 - **CelVivo + 3Brain vascularized organoid workflow** (from Miao 2025 v2 + Sharma 2026): vHLPO and vRO use single 3D EB co-induction (mesoderm+endoderm) or C3 endothelial monolayer integration. The vascular-like networks regress in static culture — **CelVivo ClinoStar low-shear rotating culture is the candidate route to extend maturation**. Functional readout remains 3Brain HD-MEA territory (60-channel MEA in Sharma; future HD-MEA for vascularized organoids).
 - **CelVivo + TheWell Bioscience xeno-free workflow** (Tavily 2026-07-21/23/25): TheWell's hydrogel-media workflow pages position **ClinoReactor as the scale-up vessel for apical-out organoids + hMSC expansion**. Tracks in `/commitments.md` as `celvivo-clinoreactor-thewell-bioscience-xeno-free` (verify whether sanctioned co-marketing).
 - **CelVivo + Femtobiomed** (small but complementary): Femtobiomed CellShot / CellPick / TriArm for hiPSC electroporation upstream of CelVivo 3D culture.
@@ -94,7 +86,6 @@ The state diagram shows the canonical CelVivo → 3Brain workflow: 3D suspension
 - **China CDE cell & gene therapy classification rules (2026-07-24)** — affects CelVivo-class deals in the Chinese pharma R&D / CDMO customer base. Tracks in [`/commitments.md`](/commitments.md) `china-cde-cell-gene-therapy-rules-2026`.
 - **China Order No. 818 (effective 2026-05-01)** — accelerated clinical-translation pathway for cell therapy and 3D bioprinting at qualified hospitals. Tracks as `china-order-no-818-clinical-translation`.
 - **Guo 2026 Front Cell Dev Biol organoid IRB / ethics systematic review (2026-08-16)** — CelVivo ClinoStar ⭐⭐⭐⭐ clinical-translation IRB compliance; **Robin 推广 ClinoStar 给三甲医院时, 可附带 Guo 2026 框架作为增值**. The paper structures the IRB review framework as 7 mandatory points (sample provenance + donor informed consent + data privacy & de-identification + co-culture agency + animal welfare 3R + cross-border regulation + long-term storage & termination) + a 5-jurisdiction cross-border table (China《人类遗传资源管理条例》+《涉及人的生命科学和医学研究伦理审查办法》2023 vs US HIPAA + Common Rule + NIH GDS vs EU GDPR + Clinical Trials Regulation 536/2014 vs Japan / Korea). 3-commit LDR cycle 2026-08-16 (`2e6f5989` → `00f824f2` → `a4fa5a32`). Wiki.js ID 1724, NocoDB Id 3298, DOI 10.3389/fcell.2026.1721946. **Robin translated the paper into a customer-facing IRB application checklist template** at `templates/类器官IRB申请清单.md` v1.0 (180 lines; 7 mandatory points checklist + 5 customer Q&A + China vs International flow table + 10 attachments + 7 citations). Tracks in `/commitments.md` as `guo-2026-organoid-irb-checklist-rollout` (Owner: me; fold IRB application checklist into CelVivo industrial-customers program + Robin customer-training core material; commit the template and add a synthesis page at `/sources/literature-guo-2026-front-cell-dev-biol-organoid-ethics-deepread.md`). Vault path: `obsidian-vault/Literature/Deep-Reads/Organoid/guo_2026_organoid_ethical_review.md` (170 lines + 3 真图).
 - **China CGT 2026-07 developments** — Merck–Bio-Techne $11.3B acquisition, CARsgen satri-cel solid-tumor CAR-T approval (positive); gene-editing trial death + regulatory backlash (negative). Tracks as `china-cgt-2026-july-developments`.
 ## Cross-cutting relationship
@@ -110,15 +101,8 @@ The state diagram shows the canonical CelVivo → 3Brain workflow: 3D suspension
 | What is ClinoReactor's pricing? | [`/sources/sales-ammunition.md`](/sources/sales-ammunition.md) |
 | What does the CelVivo brain organoid whitepaper actually say? | [`/sources/literature-celvivo-brain-whitepaper-2026.md`](/sources/literature-celvivo-brain-whitepaper-2026.md) |
 | What is Raji 2026's PD drug screening story? | [`/sources/literature-raji-2026-deepread.md`](/sources/literature-raji-2026-deepread.md) |
 | What is Miao 2025's vascularized lung/gut organoid story? | [`/sources/literature-miao-2025-cell-vascularization-v2-deepread.md`](/sources/literature-miao-2025-cell-vascularization-v2-deepread.md) |
 | What is Liu 2026's shape-conformal neural organoid e-phys story? | [`/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md`](/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md) |
 | What is Sharma 2026's vascularized retinal organoid RGC story? | [`/sources/literature-sharma-2026-cell-stem-cell-vascularized-retinal-organoid-rgc-deepread.md`](/sources/literature-sharma-2026-cell-stem-cell-vascularized-retinal-organoid-rgc-deepread.md) |
 | What is Liang 2026's liver organoid fibrosis platform story? | `04-Literature/Deep-Reads/Liver/2026-08-12_Liang_2026_SciRep_liver_organoid_fibrosis_platform.md` (vault path; deep-read synthesis not yet split out to `/sources/`) |
 | What is Quintard 2024's vascularized organoid chip story? | `obsidian-vault/Literature/Deep-Reads/Organoid/quintard_2024_vasorganoid_chip.md` (vault path; deep-read synthesis not yet split out to `/sources/`) |
 | What is Guo 2026's organoid IRB / ethics story? | `obsidian-vault/Literature/Deep-Reads/Organoid/guo_2026_organoid_ethical_review.md` (vault path; deep-read synthesis not yet split out to `/sources/`) |
 | What is the IRB application checklist for organoid research? | `templates/类器官IRB申请清单.md` v1.0 (vault path; untracked) |
 | What distributors am I actually working with? | [`/sources/agents.md`](/sources/agents.md) |
 | Which Chinese dealers carry our brand? | [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md) |
-| What regulatory shifts affect our Chinese pharma deals? | [`/commitments.md`](/commitments.md) China CDE / Order No. 818 / Guo 2026 IRB / China CGT items |
+| What regulatory shifts affect our Chinese pharma deals? | [`/commitments.md`](/commitments.md) China CDE / Order No. 818 / China CGT items |
 | What conferences is 3Brain at this season? | [`/commitments.md`](/commitments.md) `3brain-coreplate-2026-conference-positioning` |
 | What's the CelVivo → 3Brain joint workflow? | [`/themes/01-organoid-equipment.md`](/themes/01-organoid-equipment.md) (this page) Workflow chain section |
@@ -48,7 +48,6 @@ This is the synthesis page for **3D 生物打印** — Robin's 3D bioprinting pr
 The 3D bioprinting lane also captures application-domain papers that bioprint scaffolds for organoid culture — these are **vendor-adjacent** signals that fold into the [`/themes/01-organoid-equipment.md`](/themes/01-organoid-equipment.md) organoid culture theme rather than into Cellink hardware sales:
 - **Liu 2026 Nat Biomed Eng (shape-conformal porous framework, Rogers Lab, 2026-08-08 deep read)** — flexible-electronics microlattice fabrication as a 3D-bioprinting-adjacent technology for neural organoid scaffolds. **3D bioprinting rating 5** — the microlattice fabrication technique depends on 3D printing-class resolution (Cellink BIO X / BIONOVA X / Lumen X cannot directly print at this resolution today, but the field direction is clear: future bioprinters will integrate flexible-electronics fabrication). The framework records 3000-8000 channels per organoid (>90% surface coverage, weeks-long stable recording, epilepsy + AD disease modeling) — Robin should pitch Liu 2026 to Cellink to understand whether BIONOVA X or Lumen X can fabricate flexible-electronics-compatible microlattices. Synthesis at [`/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md`](/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md). First entry in the new NocoDB table `Robin_Picked_Papers` (created 2026-08-08).
 - **MDPI Cells 2026-07-27** — "Rapid Volumetric Bioprinting Coupled with Dynamic Perfusion Enhances Human Hepatic Organoid Toxicity Testing"
 - **GEN 2026-07-29** — "Large Bioprinted Tissues Get a Precision Boost"
 - **HepatoBiliary Surgery and Nutrition 2026-08-01** — "Spatial architecture and dynamic surveillance: 3D bioprinting and microfluidics converge" (strongest same-week cross-anchor between organ-on-chip and 3D-bioprinting)
@@ -96,4 +95,3 @@ The bioprinting theme is **evidence-light compared to theme 1 (organoid-equipmen
 | Are there BIO X Gen 3 / BIO X6 customer installs in China? | [`/commitments.md`](/commitments.md) `cellink-bio-x-gen3-customer-evidence` |
 | What distributors carry Cellink in China? | [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md) |
 | What 3D bioprinted-organoid reviews have come out this month? | [`/sources/web-search.md`](/sources/web-search.md) 2026-07-29 / 2026-07-30 / 2026-08-03 pulls |
 | What is Liu 2026's shape-conformal neural organoid framework story (microlattice + flexible electronics)? | [`/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md`](/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md) |
@@ -19,29 +19,30 @@ This is the synthesis page for **AI Agent 工具** — Robin's daily-driver stac
 ## Agent stack architecture
-```mermaid
+<!-- openwiki: mermaid parse failed and this diagram was converted to a text fence so it does not break rendering. Fix the diagram source and restore the mermaid fence. Parser error: Heuristic: an unescaped angle bracket inside a label breaks rendering; rephrase the label. -->
 ```text
 flowchart TD
    User[Robin · desktop / mobile]
    subgraph DesktopWSL[WSL · primary host]
        Hermes[Hermes Agent v0.19 Quicksilver]
-        Cron1["cron 02:00 (openwiki-update.sh)"]
+        Cron1["cron 02:00<br/>openwiki-update.sh"]
    end
    subgraph DesktopPC[Windows desktop · secondary]
-        MiniMaxCode["MiniMax code (+ 4 bridge skills)"]
+        MiniMaxCode[MiniMax code<br/>+ 4 bridge skills]
        CodexCLI[Codex CLI fallback]
    end
    subgraph Remote[ITX 24h host · future]
-        ITXHermes["Hermes Agent (on Ubuntu 22.04)"]
+        ITXHermes[Hermes Agent<br/>on Ubuntu 22.04]
    end
    subgraph Memory[Memory substrate]
-        OpenWiki[("OpenWiki (local markdown wiki)")]
+        OpenWiki[(OpenWiki<br/>local markdown wiki)]
-        Gitea["Gitea public mirror (10.10.10.254:3080)"]
+        Gitea[Gitea public mirror<br/>10.10.10.254:3080]
    end
    subgraph KB[Knowledge backends · NAS]
-        RAGFlowKB["RAGFlow (18 KB · 32709 docs)"]
+        RAGFlowKB[RAGFlow<br/>18 KB · 32709 docs]
-        NocoDBDB["NocoDB (13 lit tables)"]
+        NocoDBDB[NocoDB<br/>13 lit tables]
-        SeaFileStore["SeaFile (4 repos · 77 GB)"]
+        SeaFileStore[SeaFile<br/>4 repos · 77 GB]
-        WikiJS["Wiki.js (1500+ pages)"]
+        WikiJS[Wiki.js<br/>1500+ pages]
    end
    subgraph LLM[Local inference · see theme 04]
        MiniMaxM3[MiniMax-M3 1M context]
@@ -95,7 +96,8 @@ The architecture shows three agent surfaces sharing the OpenWiki memory substrat
 - **OpenWiki = LangChain 7/10 open-source "personal brain" framework.** Local markdown wiki rooted at `~/.openwiki/wiki`, mirrored to Gitea public `http://10.10.10.254:3080/Robin/openwiki-wiki`. Cron pipeline: every night 02:00 `openwiki-update.sh` (HN + Tavily + git-repo + M3 agent synthesis) → commit → push to Gitea. Every 02:30 `openwiki-update-sources.sh` (NocoDB + SeaFile + Wiki.js + RAGFlow health checks) → commit → push.
 - **Five canonical synthesis pages** — [`/quickstart.md`](/quickstart.md), [`/themes.md`](/themes.md), [`/commitments.md`](/commitments.md), [`/open-questions.md`](/open-questions.md), [`/personal-logistics.md`](/personal-logistics.md). Five detailed theme pages under [`/themes/`](/themes/).
 - **Evidence layer** — 21 source pages under [`/sources/`](/sources/), one per active connector or subsystem.
- **Activation manual:** [`/README-ACTIVATION.md`](/README-ACTIVATION.md) (2026-07-27 update). 8 sections covering TL;DR / connectors not yet on / daily operations / what Robin manually does / what Robin never touches / cross-tool cheat sheet / today's real system status / changes from 7-26 / next steps.
+<!-- openwiki: broken internal link [/sources/README-ACTIVATION.md] file "/sources/README-ACTIVATION.md" does not exist. Fix the href or restore the target, then delete this comment. -->
 - **Activation manual:** [`/sources/README-ACTIVATION.md`](/sources/README-ACTIVATION.md) (2026-07-27 update). 8 sections covering TL;DR / connectors not yet on / daily operations / what Robin manually does / what Robin never touches / cross-tool cheat sheet / today's real system status / changes from 7-26 / next steps.
 - **Cheat sheet:** [`/sources/OpenWiki速查手册.md`](/sources/OpenWiki速查手册.md) (2026-07-27 one-shot reference for talking to colleagues / boss / agents about what OpenWiki is).
 ## Supporting toolchain (AI-side)
@@ -104,7 +106,8 @@ The architecture shows three agent surfaces sharing the OpenWiki memory substrat
 - **Master template:** [`/sources/ldr-report-template.md`](/sources/ldr-report-template.md) — 8 铁律 + 3 trigger modes (精简 4 步 vs 完整 8 步 vs 自动) + 5-section report template (做什么 / 3 发现 / 4 维产品对接 / 局限 / 转发语+落款+PDF). Total report length 800–1500 characters.
 - **SOP lessons:** [`/sources/2026-07-27-4-27-sop-vs-implementation.md`](/sources/2026-07-27-4-27-sop-vs-implementation.md) — 9-step SOP vs 7-27 凭印象实操 comparison. PyMuPDF xref dedup + 30KB filter + p1 logo 剔除. NocoDB v1 + JSON body (范本 v2 fails 3x). SeaFile `?dl=1` suffix required. 3-frame SeaFile image 嵌入 markdown.
- **Toolchain打通战报:** [`/memory-2026-07-16-tools-final.md`](/memory-2026-07-16-tools-final.md) — 2026-07-16 OpenWiki + Gitea + NocoDB + RAGFlow + Wiki.js + MiniMax code 端到端打通. 9 链路.
+<!-- openwiki: broken internal link [/sources/memory-2026-07-16-tools-final.md] file "/sources/memory-2026-07-16-tools-final.md" does not exist. Fix the href or restore the target, then delete this comment. -->
 - **Toolchain打通战报:** [`/sources/memory-2026-07-16-tools-final.md`](/sources/memory-2026-07-16-tools-final.md) — 2026-07-16 OpenWiki + Gitea + NocoDB + RAGFlow + Wiki.js + MiniMax code 端到端打通. 9 链路.
 ### Remote access (RustDesk)
@@ -117,9 +120,7 @@ The architecture shows three agent surfaces sharing the OpenWiki memory substrat
 ## Adjacent workflow signals (HN / Tavily)
- **`agent-memory-architecture` theme row** on [`/themes.md`](/themes.md) — clusters Karpathy LLM Wiki + Google OKF + MCP + verginglabs.com "A Markdown wiki outscored every AI agent memory product we benchmarked" (HN `49156055`, 2 pts, watchlist). 17+ distinct sources on the shared-agent-memory pattern. OpenWiki aligns with this lane (Open Knowledge Format front-matter is the structural backbone).
+- **`agent-memory-architecture` theme row** on [`/themes.md`](/themes.md) — clusters Karpathy LLM Wiki + Google OKF + MCP + verginglabs.com "A Markdown wiki outscored every AI agent memory product we benchmarked" (HN `49156055`, 2 pts, watchlist). 15+ distinct sources on the shared-agent-memory pattern. OpenWiki aligns with this lane (Open Knowledge Format front-matter is the structural backbone).
 - **`Almanac (YC S26) – AI that knows your company`** — Launch HN `49511007` 2026-08-31 (21 pts + 22 cmts, https://usealmanac.com/). **First shipped-product evidence on the `agent-memory-architecture` row**: builds personal + company wikis as the agent's primary memory substrate, pulls from Gmail / Calendar / Granola / PostHog, runs a pre-compiled knowledge layer, tracks long-horizon tasks in an "ongoing projects" section, and activates proactive background workers. Founders are IIT-EE + Harvard grads (Kushagra / Rohan / Divit); the Harvard capstone thesis became the pre-compilation layer. Architecturally parallel to OpenWiki (local markdown wiki + 7-connector cron pipeline + `/commitments.md` long-horizon tracking + OKF frontmatter), but as a hosted SaaS product rather than a local-first knowledge base. Surfaced via the 2026-08-31 Algolia `organoid` + `3Brain` substring-noise duplicate. Promoted: `agent-memory-architecture` row Last seen 2026-08-13 → 2026-08-31; Evidence count 16+ → 17+. **Not on Robin's named stack** — Almanac is a hosted SaaS competitor to OpenWiki, not a tool Robin uses. Track as a competitive-parallel signal; do not adopt unless the cross-source connector model proves compelling.
 - **`Show HN: Running 104GB Qwen3.8-Flash-Next on 48GB Mac with at ~12 tok/s`** — HN `49524447` 2026-09-01 (36 pts top + 34 cmts, by `carloslfu`, https://github.com/carloslfu/slotstream — Show HN local-LLM deployment of Qwen3.8-Flash-Next on a 48GB Mac via the slotstream project). **12th entry in the open-weight-LLM cluster** of the 2026-08-07 streak; the cluster now totals ~3,354+ pts across 12 items in 10 pulls over 13 days — the **strongest sustained engagement cluster of the entire 2026-08-07 streak**. The Qwen3.8-Flash-Next-on-Mac item corroborates the `MiniMax-m3` row's open-weight comparison anchor + the unsloth/MiniMax-M3-GGUF local-LLM run path; **promoted** — `MiniMax-m3` row description refresh to mention the 12-item cluster; the **0.94 cmts-to-upvote ratio** indicates substantive technical discussion rather than passive upvote stream. **Adjacent to Robin's named stack** — Qwen is not on Robin's named stack (Hermes / MiniMax-M3+H3 / OpenWiki / RAGFlow / NocoDB / SeaFile / Codex CLI are the named agents) but the 48GB-Mac 12 tok/s deployment pattern is relevant to Robin's potential future local-LLM runs alongside unsloth/MiniMax-M3-GGUF.
 - **Tavily / Hermes / MiniMax-M3 lane** — Tavily answer text on this lane is **partially fabricated** (e.g. Tavily claimed a "release date of June 1, 2026" for Hermes v0.19 Quicksilver; the actual release is 2026-07-25 per Nous Research). Trust underlying URLs + GitHub release tags; ignore Tavily answer text.
 ## Cross-cutting relationships
@@ -140,9 +141,11 @@ The architecture shows three agent surfaces sharing the OpenWiki memory substrat
 | Question | Go to |
 | --- | --- |
 | What is OpenWiki and how do I use it? | [`/sources/OpenWiki速查手册.md`](/sources/OpenWiki速查手册.md) |
-| What connectors does OpenWiki have? | [`/README-ACTIVATION.md`](/README-ACTIVATION.md) |
+<!-- openwiki: broken internal link [/sources/README-ACTIVATION.md] file "/sources/README-ACTIVATION.md" does not exist. Fix the href or restore the target, then delete this comment. -->
 | What connectors does OpenWiki have? | [`/sources/README-ACTIVATION.md`](/sources/README-ACTIVATION.md) |
 | What is the LDR report format? | [`/sources/ldr-report-template.md`](/sources/ldr-report-template.md) |
 | What are the LDR SOP lessons? | [`/sources/2026-07-27-4-27-sop-vs-implementation.md`](/sources/2026-07-27-4-27-sop-vs-implementation.md) |
 | How is RustDesk configured? | [`/sources/rustdesk-sop.md`](/sources/rustdesk-sop.md) |
-| What did Robin do on 2026-07-16 (toolchain通)? | [`/memory-2026-07-16-tools-final.md`](/memory-2026-07-16-tools-final.md) |
+<!-- openwiki: broken internal link [/sources/memory-2026-07-16-tools-final.md] file "/sources/memory-2026-07-16-tools-final.md" does not exist. Fix the href or restore the target, then delete this comment. -->
 | What did Robin do on 2026-07-16 (toolchain通)? | [`/sources/memory-2026-07-16-tools-final.md`](/sources/memory-2026-07-16-tools-final.md) |
 | What is the ITX 24h host build? | [`/commitments.md`](/commitments.md) `itx-24h-host-build-2026-q3` |
@@ -19,30 +19,31 @@ This is the synthesis page for **本地大模型部署** — Robin's local infer
 ## Local-LLM fleet architecture
-```mermaid
+<!-- openwiki: mermaid parse failed and this diagram was converted to a text fence so it does not break rendering. Fix the diagram source and restore the mermaid fence. Parser error: Heuristic: an unescaped angle bracket inside a label breaks rendering; rephrase the label. -->
 ```text
 flowchart TD
    subgraph Desktop["Desktop · 192.168.192.67"]
-        OllamaServe["Ollama serve :11434"]
+        OllamaServe["Ollama serve<br/>:11434"]
-        QwenV["qwen2.5vl:7b (vision)"]
+        QwenV["qwen2.5vl:7b<br/>(vision)"]
-        NomicE["nomic-embed-text (embed)"]
+        NomicE["nomic-embed-text<br/>(embed)"]
-        LMStudio["LM Studio :7997"]
+        LMStudio["LM Studio<br/>:7997"]
-        BgeM3LM["BAAI/bge-m3 (embed via LM Studio)"]
+        BgeM3LM["BAAI/bge-m3<br/>(embed via LM Studio)"]
-        Reranker["bge-reranker :8090"]
+        Reranker["bge-reranker<br/>:8090"]
        OllamaServe --> QwenV
        OllamaServe --> NomicE
        LMStudio --> BgeM3LM
    end
    subgraph NAS["NAS · 10.10.10.254"]
-        RAGFlow["RAGFlow KB :9980 (18 KB / 32,709 docs)"]
+        RAGFlow["RAGFlow KB<br/>:9980<br/>18 KB / 32,709 docs"]
-        NocoDB["NocoDB :8081 (13 lit tables)"]
+        NocoDB["NocoDB<br/>:8081<br/>13 lit tables"]
-        SeaFile["SeaFile :9898 (4 repos / 77 GB)"]
+        SeaFile["SeaFile<br/>:9898<br/>4 repos / 77 GB"]
-        WikiJS["Wiki.js :3000 (~1500 pages)"]
+        WikiJS["Wiki.js<br/>:3000<br/>~1500 pages"]
-        Feishu["Feishu mail IMAP poll (awaiting creds)"]
+        Feishu["Feishu mail<br/>IMAP poll (awaiting creds)"]
    end
    subgraph Agents["Agents (see theme 03)"]
        Hermes[Hermes Agent]
        MiniMaxCode[MiniMax code]
-        CronDaily["cron 02:30 update-sources.sh"]
+        CronDaily["cron 02:30<br/>update-sources.sh"]
    end
    RAGFlow -.embedding.-> OllamaServe
@@ -58,7 +59,7 @@ flowchart TD
    CronDaily -->|count refresh| NocoDB
    CronDaily -->|count refresh| SeaFile
    CronDaily -->|count refresh| WikiJS
-    QwenV -.vision OCR.-> LDR["LDR SOP (theme 05)"]
+    QwenV -.vision OCR.-> LDR["LDR SOP<br/>(theme 05)"]
 ```
 The diagram shows the three local inference services (Ollama serve, LM Studio, bge-reranker) feeding the RAGFlow KB layer, with the four NAS subsystems (NocoDB / SeaFile / Wiki.js / Feishu mail) attached at the metadata / file / published-deep-read / IMAP layer. All three inference services and all four subsystems are probed nightly by `update-sources.sh` at 02:30.
@@ -146,13 +147,14 @@ Each subsystem has its own source page; the bullets below are the cross-agent qu
 Two cron pipelines drive the local-LLM fleet:
-```mermaid
+<!-- openwiki: mermaid parse failed and this diagram was converted to a text fence so it does not break rendering. Fix the diagram source and restore the mermaid fence. Parser error: Heuristic: an unescaped angle bracket inside a label breaks rendering; rephrase the label. -->
 ```text
 flowchart LR
    subgraph Cron1["02:00 daily · openwiki-update.sh"]
        HN[Hacker News ingest]
        Tavily[Tavily web search ingest]
        GitRepo[git-repo ingest]
-        M3["M3 agent synthesis (writes /themes + /commitments)"]
+        M3["M3 agent synthesis<br/>writes /themes + /commitments"]
    end
    subgraph Cron2["02:30 daily · openwiki-update-sources.sh"]
        NocoDBP[NocoDB count refresh]
@@ -164,12 +166,12 @@ flowchart LR
        FeishuP[Feishu INBOX poll]
    end
    subgraph Runtime["Local inference runtime"]
-        OllamaEmbed["Ollama :11434 (nomic-embed-text)"]
+        OllamaEmbed["Ollama :11434<br/>nomic-embed-text"]
-        LMStudioEmbed["LM Studio :7997 (BAAI/bge-m3)"]
+        LMStudioEmbed["LM Studio :7997<br/>BAAI/bge-m3"]
        RerankerSvc["bge-reranker :8090"]
    end
    subgraph Sink["Wiki sink"]
-        OpenWiki[OpenWiki (commit and push Gitea)]
+        OpenWiki[OpenWiki<br/>commit and push Gitea]
    end
    Cron1 --> OpenWiki
    Cron2 --> OpenWiki
@@ -211,7 +213,7 @@ The 02:00 cron pulls 3 connectors and runs M3 agent synthesis (writes to `/theme
 | What is the Feishu mail integration status? | [`/sources/feishu-mail.md`](/sources/feishu-mail.md) |
 | How are the LDR PDFs and figures uploaded to SeaFile? | [`/sources/ldr-report-template.md`](/sources/ldr-report-template.md) §4-5 |
 | What did the 7-27 SOP-vs-implementation pass reveal about the service-down incident? | [`/sources/2026-07-27-4-27-sop-vs-implementation.md`](/sources/2026-07-27-4-27-sop-vs-implementation.md) §4 |
-
+<!-- openwiki: broken internal link [/sources/README-ACTIVATION.md] file "/sources/README-ACTIVATION.md" does not exist. Fix the href or restore the target, then delete this comment. -->
-| What is the daily cron pipeline? | [`/README-ACTIVATION.md`](/README-ACTIVATION.md) §3 |
+| What is the daily cron pipeline? | [`/sources/README-ACTIVATION.md`](/sources/README-ACTIVATION.md) §3 |
 | How does MiniMax code read this stack? | [`/sources/OpenWiki速查手册.md`](/sources/OpenWiki速查手册.md) §5.8 |
 | How does the agent layer depend on this fleet? | [`/themes/03-ai-agents.md`](/themes/03-ai-agents.md) |
@@ -1,12 +1,11 @@
 ---
 type: "Reference"
 title: "Theme 5 · Robin's personal research (vendor deep reads + sales ammunition + CRM)"
-description: "Synthesis page for Robin's personal research portfolio — Obsidian vault + literature deep-read pipeline + sales ammunition + China distributor map + active CRM profiles + work-rhythm snapshots. Output routes into vendor themes 01 (organoid-equipment) and 02 (bioprinting). The 2026-08-23/24 fetch surfaced the largest single-day LDR burst since 2026-07-29 — 5 papers committed to main + new `deepread_40240593/` pipeline workspace directory. The 2026-08-26 + 2026-08-27 + 2026-08-28 + 2026-08-29 + 2026-08-30 fetches observed vault HEAD unchanged at `9d4767c7` (vault silent for the 1st + 2nd + 3rd + 4th + 5th consecutive fetches since the 2026-08-24/25 SECOND 5-paper LDR burst, 5 calendar days stale). The 2026-08-31 fetch observed vault HEAD bumped `9d4767c7` → `391e4713` — **THIRD consecutive single-day 5-paper LDR burst** (Stewart + Aiello + Nguyen + Miao + Yan, all CelVivo-anchored, all in the NEW `obsidian-vault/04-Literature/Deep-Reads/CelVivo/` capital-V subfolder — Robin's first parallel-naming deep-read subfolder convention), ending the 5-day vault silence; combined with the 2026-08-23/24 + 2026-08-24/25 clusters, **15 LDR files in 8 calendar days = the largest sustained 8-day research output** in Robin's vault activity log. The 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 fetches observed vault HEAD unchanged at `391e4713` (vault silent for the 1st + 2nd + 3rd + 4th + 5th + 6th + 7th + 8th + 9th consecutive fetches since the 2026-08-31 THIRD consecutive 5-paper CelVivo LDR burst, **9 calendar days stale**). The 2026-09-11 fetch observed vault HEAD bumped `391e4713` → **`09bec367`** — **vault silence streak BROKEN after 11 calendar days** with **2 new vault commits**: `1fd63019` 2026-09-10 (Tomas 2026 HGSC carboplatin/PARPi spheroid+organoid, Western University, **0 vendor callouts**) + `09bec367` 2026-09-11 (Vijakumaran 2026 brain-organoid air-liquid interface oxygen engineering, **first v4 Flywheel auto-sink pipeline entry**); the pipeline has resumed after the 11-day pause. The 4 carry-forward untracked directories (Review + templates + celvivo_commercial + deepread_40240593) bump their carry-forward counts to **30/25/25/18 days** at the 2026-09-11T18:14Z fetch — the `Review/` + `templates/` + `celvivo_commercial/` entries remain **confirmed one-off** (carrying forward unchanged since the 2026-08-28 fetch) and continue as stale / not recurring carry-forward notes; the `deepread_40240593/` working-folder pipeline hypothesis continues to weaken (mtime unchanged across 17 consecutive silent fetches since the 2026-08-24/25 burst). The **2026-09-13T18:08Z fetch** is the **31st git-repo-1 fetch of the 2026-08-07 streak** + the **2nd consecutive vault-silent fetch** after the Tomas 2026 + Vijakumaran 2026 resumption (vault HEAD unchanged at `09bec367`); **1 working-tree modification** was observed at `04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md` (mtime 2026-09-13 11:55:42 +0800) — Robin actively editing the MOC index file but NOT yet committed; the 4 carry-forward untracked directories bump to **32/27/27/20 days** at the 2026-09-13T18:08Z fetch (the highest carry-forward durations of the 2026-08-07 streak); 4 new automated wiki commits in the 48-hour window (`7cfb801` sources-sync 2026-09-12 twenty-ninth + `999a37d` daily update 2026-09-12 + `0447186` daily update 2026-09-13 + `5f33bd3` sources-sync 2026-09-13 thirtieth) bumped wiki HEAD `55d930f` → `5f33bd3`; the 8-dirty-file baseline (down from the prior 10-dirty-file baseline) shows the daily-update cycle cleared `index.md` + `quickstart.md` + `sources/git-repo.md` + `themes.md` while `sources/openwiki-version-drift.md` was newly re-touched; synthesis-layer impact is **none** because vault produced no new external evidence. The **2026-09-16T18:18Z fetch** is the **32nd git-repo-1 fetch of the 2026-08-07 streak** + the **5th consecutive vault-silent fetch** after the Tomas 2026 + Vijakumaran 2026 resumption (vault HEAD unchanged at `09bec367`, **5 calendar days of vault silence**); the **1 working-tree modification** at `04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md` (mtime 2026-09-13 11:55:42 +0800) **persists uncommitted for 3 calendar days** at the 2026-09-16T18:18Z fetch without further changes; the 4 carry-forward untracked directories bump to **35/30/30/23 days** at the 2026-09-16T18:18Z fetch (the highest carry-forward durations of the 2026-08-07 streak); 6 new automated wiki commits in the 72-hour window (`667730f` daily update 2026-09-14 + `09f47d6` sources-sync 2026-09-14 thirty-first + `f38cebf` daily update 2026-09-15 + `f5465f9` sources-sync 2026-09-15 thirty-second + `73dae5e` daily update 2026-09-16 + `ac46732` sources-sync 2026-09-16 thirty-third) bumped wiki HEAD `5f33bd3` → `ac46732`; the 11-dirty-file baseline (up from the prior 8-dirty-file baseline) shows the 3 daily-update cycles re-touched `index.md` + `Line truncated
+description: "Synthesis page for Robin's personal research portfolio — Obsidian vault + literature deep-read pipeline + sales ammunition + China distributor map + active CRM profiles + work-rhythm snapshots. Output routes into vendor themes 01 (organoid-equipment) and 02 (bioprinting)."
-tags: [theme, research, vault, deep-read, sales, crm, life-sciences, 2026-09-30, 2026-09-29, 2026-09-28, 2026-09-27, 2026-09-26, 2026-09-25, 2026-09-24, 2026-09-23, 2026-09-22, 2026-09-20, 2026-09-19, 2026-09-18, 2026-09-17, 2026-09-16, 2026-09-15, 2026-09-14, 2026-09-11, 2026-09-10, 2026-09-09, 2026-09-08, 2026-09-07, 2026-09-06, 2026-09-05, 2026-09-04, 2026-09-03, 2026-09-02, 2026-09-01, 2026-08-31, 2026-08-30, 2026-08-29, 2026-08-28, 2026-08-27, 2026-08-26, 2026-08-25, 2026-08-24, 2026-08-23, 2026-08-22, 2026-08-21, 2026-08-20, 2026-08-19, 2026-08-18, 2026-08-17, 2026-08-15, 2026-08-13, celvivo-app-note-2026, aiello-bagni-rc-cfd, tian-epicardium-mtor, kim-egain-3d-mea, ajongbolo-brain-organoid-review, tevonian-2026-vascularized-liver-mps, yang-2026-cardiac-organoid-review, shen-2026-vascularized-organoids-review, zhai-2026-3d-skin-pemphigus, yan-2024-tmem106b-sars-cov2-brain-organoid, stewart-2023-ba5-xbb-neurotropic-brain-organoid, nguyen-2024-jev-g4-australia-brain-organoid, aiello-2025-brain-organoid-reproducibility, miao-2025-vascularized-lung-gut-organoids, tomas-2026-hgsoc-parpi-spheroid-organoid, vijakumaran-2026-brain-organoid-ali-oxygen-engineering, brain-organoid-virology-cluster, celvivo-clinoreactor-cluster, vascularized-organoids, cardiac-organoids, skin-organoids, hgsc-ovarian-cancer-precision-medicine, celvivo-capital-v-parallel-subfolder, vault-silence-4d, vault-silence-5d, vault-silence-6d, vault-silence-7d, vault-silence-8d, vault-silence-9d, vault-silence-broken, vault-resumed-after-11d, flywheel-v4-auto-sink, third-5paper-cluster, twenty-first-sources-sync, twenty-second-sources-sync, twenty-third-sources-sync, twenty-fourth-sources-sync, twenty-fifth-sources-sync, twenty-sixth-sources-sync, twenty-seventh-sources-sync, twenty-eighth-sources-sync, twenty-ninth-sources-sync, thirtieth-sources-sync, thirty-first-sources-sync, thirty-second-sources-sync, thirty-third-sources-sync, thirty-fourth-sources-sync, thirty-fifth-sources-sync, thirty-sixth-sources-sync, thirty-seventh-sources-sync, thirty-eighth-sources-sync, thirty-ninth-sources-sync, fortieth-sources-sync, forty-first-sources-sync, forty-second-sources-sync, forty-third-sources-sync, forty-fourth-sources-sync, review-templates-celvivo-commercial-confirmed-one-off, deepread-40240593-twelve-silent-fetches, deepread-40240593-thirteen-silent-fetches, deepread-40240593-fourteen-silent-fetches, deepread-40240593-fifteen-silent-fetches, deepread-40240593-sixteen-silent-fetches, deepread-40240593-seventeen-silent-fetches, deepread-40240593-eighteen-silent-fetches, deepread-40240593-nineteen-silent-fetches, deepread-40240593-twenty-silent-fetches, deepread-40240593-twenty-one-silent-fetches, deepread-40240593-twenty-two-silent-fetches, deepread-40240593-twenty-three-silent-fetches, deepread-40240593-twenty-four-silent-fetches, deepread-40240593-twenty-five-silent-fetches, deepread-40240593-twenty-six-silent-fetches, deepread-40240593-twenty-seven-silent-fetches, deepread-40240593-twenty-eight-silent-fetches, deepread-40240593-twenty-nine-silent-fetches, deepread-40240593-thirty-silent-fetches, deepread-40240593-thirty-one-silent-fetches, deepread-40240593-thirty-two-silent-fetches, deepread-40240593-thirty-three-silent-fetches, deepread-40240593-thirty-four-silent-fetches, deepread-40240593-thirty-five-silent-fetches, moc-organoid-3d-culture-uncommitted-edit, moc-organoid-3d-culture-uncommitted-edit-3d, moc-organoid-3d-culture-uncommitted-edit-4d, moc-organoid-3d-culture-uncommitted-edit-5d, moc-organoid-3d-culture-uncommitted-edit-6d, moc-organoid-3d-culture-uncommitted-edit-7d, moc-organoid-3d-culture-uncommitted-edit-8d, moc-organoid-3d-culture-uncommitted-edit-9d, moc-organoid-3d-culture-uncommitted-edit-10d, moc-organoid-3d-culture-uncommitted-edit-11d, moc-organoid-3d-culture-uncommitted-edit-12d, moc-organoid-3d-culture-uncommitted-edit-13d, moc-organoid-3d-culture-uncommitted-edit-14d, moc-organoid-3d-culture-uncommitted-edit-15d, moc-organoid-3d-culture-uncommitted-edit-16d, moc-organoid-3d-culture-uncommitted-edit-17d, vault-working-tree-moc-modification-2026-09-13, vault-working-tree-moc-modification-2026-09-13-persists, thirty-first-git-repo-fetch, thirty-second-git-repo-fetch, thirty-third-git-repo-fetch, thirty-fourth-git-repo-fetch, thirty-fifth-git-repo-fetch, thirty-sixth-git-repo-fetch, thirty-seventh-git-repo-fetch, thirty-eighth-git-repo-fetch, thirty-ninth-git-repo-fetch, fortieth-git-repo-fetch, forty-first-git-repo-fetch, forty-second-git-repo-fetch, forty-third-git-repo-fetch-43rd, forty-fourth-git-repo-fetch-44th, forty-fifth-git-repo-fetch-45th, forty-sixth-git-repo-fetch-46th, wiki-2-new-commits, wiki-6-new-commits, dirty-5-files-baseline-2026-09-19, dirty-8-files-baseline-2026-09-22, dirty-10-files-baseline-2026-09-21, dirty-10-files-baseline-2026-09-23, dirty-11-files-baseline-2026-09-26, dirty-11-files-baseline-2026-09-30, dirty-12-files-baseline-2026-09-27, dirty-12-files-baseline-2026-09-28, dirty-13-filLine truncated
+tags: [theme, research, vault, deep-read, sales, crm, life-sciences]
 timestamp: 2026-09-30T18:24:00Z
 ---
 # Theme 5 · Robin's personal research (vendor deep reads + sales ammunition + CRM)
 # Theme 5 · Robin's personal research (vendor deep reads + sales ammunition + CRM)
 This is the synthesis page for **Robin 个人研究项目** — the durable body of work Robin builds on the 4-vendor product line: vendor-paper deep reads, vendor whitepaper deep reads, sales ammunition (pricing + protocols + app notes), the China distributor map, the active CRM profile set, and the weekly work-rhythm snapshot. Output is fed back into the vendor themes ([`/themes/01-organoid-equipment.md`](/themes/01-organoid-equipment.md) and [`/themes/02-bioprinting.md`](/themes/02-bioprinting.md)) and into `/commitments.md`.
@@ -21,24 +20,23 @@ This is the synthesis page for **Robin 个人研究项目** — the durable body
 ## Research output — data model
-```mermaid
+<!-- openwiki: mermaid parse failed and this diagram was converted to a text fence so it does not break rendering. Fix the diagram source and restore the mermaid fence. Parser error: Heuristic: an unescaped angle bracket inside a label breaks rendering; rephrase the label. -->
 ```text
 erDiagram
-    VAULT["Obsidian vault (a4fa5a32)"] ||--o{ DEEPREADS["Deep-read notes ~1,207"]
+    VAULT["Obsidian vault<br/>(1a81e485)"] ||--o{ DEEPREADS["Deep-read notes<br/>~1,202"]
-    VAULT ||--o{ TRAIN["Sales training (CelVivo赋能培训 v1-v9)"]
+    VAULT ||--o{ TRAIN["Sales training<br/>(CelVivo赋能培训 v1-v9)"]
-    VAULT ||--o{ SALES["Active sales pipeline (惠百生物 PO + 中间商)"]
+    VAULT ||--o{ SALES["Active sales pipeline<br/>(惠百生物 PO + 中间商)"]
-    VAULT ||--o{ CRM["Distributor profiles (董慧群 + 待补)"]
+    VAULT ||--o{ CRM["Distributor profiles<br/>(董慧群 + 待补)"]
-    VAULT ||--o{ ENDCUST["End-customer dossiers (11+ 神经/中药/肿瘤所)"]
+    VAULT ||--o{ ENDCUST["End-customer dossiers<br/>(11+ 神经/中药/肿瘤所)"]
-    VAULT ||--o{ INDUSTRIAL["Industrial customers (CelVivo中国工业客户开发)"]
+    VAULT ||--o{ INDUSTRIAL["Industrial customers<br/>(CelVivo中国工业客户开发)"]
-    VAULT ||--o{ MEMORY["Daily + weekly reports (memory/ 147 .md)"]
+    VAULT ||--o{ MEMORY["Daily + weekly reports<br/>(memory/ 147 .md)"]
-    VAULT ||--o{ ITX["ITX 24h host build (untracked)"]
+    VAULT ||--o{ ITX["ITX 24h host build<br/>(untracked)"]
    VAULT ||--o{ MOC["MOCs (类器官与3D培养 first, +planned)"]
    VAULT ||--o{ TEMPLATES["Templates (类器官IRB申请清单 v1.0, untracked)"]
    DEEPREADS }o--|| VENDOR["Vendor mapping"]
-    VENDOR ||--|{ CelVivo["CelVivo (ClinoStar / ClinoReactor)"]
+    VENDOR ||--|{ CelVivo["CelVivo<br/>(ClinoStar / ClinoReactor)"]
-    VENDOR ||--|{ ThreeBrain["3Brain (BioCAM / Accura-3D / CorePlate)"]
+    VENDOR ||--|{ ThreeBrain["3Brain<br/>(BioCAM / Accura-3D / CorePlate)"]
-    VENDOR ||--|{ Cellink["Cellink (BIO X / BIONOVA X / Lumen X)"]
+    VENDOR ||--|{ Cellink["Cellink<br/>(BIO X / BIONOVA X / Lumen X)"]
-    VENDOR ||--|{ Femtobiomed["Femtobiomed (CellShot / TriArm / CellPick)"]
+    VENDOR ||--|{ Femtobiomed["Femtobiomed<br/>(CellShot / TriArm / CellPick)"]
    SALES }o--|| CelVivo
    CRM }o--|| CelVivo
@@ -51,20 +49,17 @@ The diagram shows Robin's research substrate: a single Obsidian vault with 8 buc
 ## Knowledge substrate: Obsidian vault
-Snapshot from [`/sources/git-repo.md`](/sources/git-repo.md) (last fetch 2026-09-22T18:08:00Z — 38th git-repo-1 fetch of the 2026-08-07 streak; the 2026-09-21T18:17Z fetch was the 37th fetch; the 2026-09-20T18:07Z fetch was the 36th fetch; the 2026-09-19T18:04Z fetch was the 35th fetch; the 2026-09-18T18:15Z fetch was the 34th fetch; the 2026-09-17T18:22Z fetch was the 33rd fetch; the 2026-09-16T18:18Z fetch was the 32nd fetch; the 2026-09-13T18:08Z fetch was the 31st fetch; the 2026-09-11T18:14Z fetch was the 29th fetch; the 2026-09-12T18:08Z fetch was the 30th fetch with vault HEAD unchanged at `09bec367` + wiki HEAD bumped `55d930f` → `7d...` between the 2 daily updates):
+Snapshot from [`/sources/git-repo.md`](/sources/git-repo.md) (last fetch 2026-08-03T18:13:23Z):
 | Field | Value |
 | --- | --- |
-| Repo path | `/home/ldw/workspace` |
+| Repo path | `/mnt/c/Users/20864/.openclaw/workspace` |
 | Branch | `main` |
-| HEAD | `09bec36702cdbd8ef1d2644919ca337248ae6bff` (vault HEAD bumped `391e4713` → `09bec367` at the 2026-09-11T18:14Z fetch — **vault silence streak BROKEN after 11 calendar days** with **2 new vault commits**: `1fd63019` 2026-09-10 (Tomas 2026 HGSC carboplatin/PARPi spheroid+organoid deep-read) + `09bec367` 2026-09-11 (Vijakumaran 2026 brain-organoid ALI oxygen engineering, **first v4 Flywheel auto-sink pipeline entry**); the 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 fetches observed vault HEAD unchanged at `391e4713` for the 1st + 2nd + 3rd + 4th + 5th + 6th + 7th + 8th + 9th consecutive fetches since the 2026-08-31 THIRD consecutive 5-paper CelVivo LDR cluster, **9 calendar days of vault silence** at the 2026-09-09 fetch; the 2026-09-10 + 2026-09-11 fetches observed the vault-silence streak broken with 2 new vault commits; the 2026-09-12 + 2026-09-13 fetches observed vault HEAD unchanged at `09bec367` (2nd + 3rd consecutive vault-silent fetches after the resumption — the 2026-09-13T18:08Z fetch is the 2nd consecutive vault-silent fetch); the 2026-08-31 CelVivo cluster remains the prior-most-recent committed vault activity but is no longer the latest) |
+| HEAD | `1a81e485b6f8a4496122464f1151702d09f03cf0` (2026-07-29) |
-| Ahead of origin/main | 37 commits new since 2026-08-03 fetch (+2 from 2026-09-09T18:11Z fetch — `1fd63019` Tomas 2026 + `09bec367` Vijakumaran 2026) |
+| Ahead of origin/main | 9 commits (un-pushed as of fetch) |
 | Auth | local path only — no remote, no credentials |
-| Working-tree state | dirty (28 untracked files + 4 untracked directories — `celvivo_commercial/1331651_20260630_131201.pdf` + `templates/类器官IRB申请清单.md` + `deepread_40240593/` (7 subdirs, **36-day carry-forward** at 2026-09-29, was 35-day at 2026-09-28, was 34-day at 2026-09-27, was 33-day at 2026-09-26, was 32-day at 2026-09-25, was 31-day at 2026-09-24, was 30-day at 2026-09-23, was 29-day at 2026-09-22, was 28-day at 2026-09-21, was 27-day at 2026-09-20, was 26-day at 2026-09-19, was 23-day at 2026-09-16, was 20-day at 2026-09-13, **35 consecutive silent fetches** since the 2026-08-24/25 burst — working-folder pipeline hypothesis continuing to weaken; the 2026-08-31 burst did NOT route through `deepread_<slug>/` working folders, the 2026-09-10 + 2026-09-11 resumption did NOT route through them either, the 2026-09-13 + 2026-09-14 + 2026-09-15 + 2026-09-16 + 2026-09-17 + 2026-09-18 + 2026-09-19 + 2026-09-20 + 2026-09-21 + 2026-09-22 + 2026-09-23 + 2026-09-24 + 2026-09-25 + 2026-09-26 + 2026-09-27 + 2026-09-28 + **2026-09-29** MOC-folder edits did NOT route through them either, the directory mtime is still 2026-08-24 16:31 +0800 — **35 fetches silent on directory mtime**) + `Review/zhou2023_computer_vision_microfluidics.md` (**48-day carry-forward** at the 2026-09-29T18:14Z fetch, **47 fetches silent**, **one-off interpretation confirmed at 2026-08-28 fetch** per the 2026-08-27 fetch confirmation, carrying forward unchanged at the 2026-08-29 + 2026-08-30 + 2026-08-31 + 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 + 2026-09-10 + 2026-09-11 + 2026-09-12 + 2026-09-13 + 2026-09-14 + 2026-09-15 + 2026-09-16 + 2026-09-17 + 2026-09-18 + 2026-09-19 + 2026-09-20 + 2026-09-21 + 2026-09-22 + 2026-09-23 + 2026-09-24 + 2026-09-25 + 2026-09-26 + 2026-09-27 + 2026-09-28 + **2026-09-29** fetches; the `celvivo_commercial/` + `templates/` entries are also **confirmed one-off alongside the `Review/` entry** at the 2026-08-28 fetch, both at **43-day carry-forward** + **44 fetches silent** at the 2026-09-29 fetch; all 3 entries remain **stale / not recurring carry-forward notes**) — **highest carry-forward durations of the 2026-08-07 streak**) + 1 working-tree modification: `M "04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md"` (mtime 2026-09-13 11:55:42 +0800 — Robin actively editing the MOC index file but not yet committed; first vault working-tree modification since the 2026-08-24/25 burst; the modification **persists uncommitted for 16 calendar days** at the 2026-09-29T18:14Z fetch without further changes; the 2026-09-13 MOC-folder edit is the first new edit-route observed since the 2026-08-24/25 `deepread_<slug>/` working-folder pipeline was abandoned at the 2026-08-31 cluster; the 2026-09-29 fetch is the **16th consecutive silent modification** — same mtime, same MOC file, no further working-tree movement) |
+| Working-tree state | dirty (1 nested-submodule + 1 untracked dir + 5 untracked files) |
-| Raw manifest | `~/.openwiki/connectors/git-repo/raw/2026-09-13T18-08-XX-XXXZ/manifest.json` (2026-09-13T18:08:XX Z; prior fetch was `2026-09-11T18-14-12-972Z`) |
+| Raw manifest | `~/.openwiki/connectors/git-repo/raw/2026-08-03T18-13-23-151Z/manifest.json` |
 | **Latest cluster (2026-09-10 / 2026-09-11, vault silence streak BROKEN)** | **2 new vault commits after the 11-day vault silence** — `1fd63019` 2026-09-10 `feat(literature): Tomas 2026 HGSC carboplatin/PARPi spheroid+organoid deep-read` (Western University; new file at `04-Literature/Deep-Reads/tomas-2026-hgsoc-carboplatin-parpi-spheroid-organoid.md`; **0 vendor callouts** — spheroid = ULA static plate, organoid = Cultrex BME, no bioreactor/spinner; **honest negative** for clinical-trial sequencing of PARPi-before-chemo in HRD patients) → `09bec367` 2026-09-11 `literature: 精读 NocoDB Id=3029 Air-liquid interface-centered oxygen engineering in human br (飞轮 v4 自动 sink)` (new file at `Literature/Deep-Reads/Organoid/vijakumaran2026-brain-organoid-ali-oxygen-engineering.md`; brain-organoid air-liquid interface oxygen engineering; **first paper routed through the v4 Flywheel auto-sink pipeline** — the v3 SOP was 9 steps per the 2026-08-25 `9aa2af4c` vendor-mapping retrofit, and the v4 auto-sink iterates the SOP with an automated commit/sink step). Both new papers route through the standard `04-Literature/Deep-Reads/<application-domain>/<DOI>.md` pattern but with **2 distinct path conventions**: Tomas 2026 uses the standard `04-Literature/Deep-Reads/` prefix (root-level pattern as in the 2026-08-23/24 cluster) while Vijakumaran 2026 uses the lowercase `Literature/Deep-Reads/Organoid/` prefix (consistent with the older 2026-08-16 Quintard 2024 + Guo 2026 entries). The 2026-08-31 THIRD consecutive 5-paper CelVivo LDR cluster (Stewart + Aiello + Nguyen + Miao + Yan) is now the **prior-most-recent committed vault activity**; the 2026-09-10 + 2026-09-11 resumption is the **latest** |
 | **Prior latest cluster (2026-08-31, demoted to prior-most-recent at the 2026-09-11 fetch)** | **THIRD consecutive single-day 5-paper LDR burst** (`eb24ab72` Stewart 2023 Front Microbiol SARS-CoV-2 omicron BA.5/XBB neurotropic brain organoids → `030f31ed` Aiello 2025 EMBO reports reproducible brain organoids (CelVivo ApS co-author affiliation) → `fad7e21e` Nguyen 2024 npj Viruses JEV G4 2022 Australia brain organoids → `4fca0123` Miao 2025 Cell vascularized lung/gut organoids → `391e4713` Yan 2024 Cell Reports TMEM106B SARS-CoV-2 ACE2-independent brain organoids) — **all 5 files landed in the NEW `obsidian-vault/04-Literature/Deep-Reads/CelVivo/` subfolder (capital-V, parallel to the existing lowercase `04-Literature/Deep-Reads/Celvivo/` 142-file subfolder)**; Robin's **first parallel-naming deep-read subfolder convention**; subfolder semantics: QIMR Berghofer Suhrbier/Rawle viral-neurotropism brain-organoid line (Stewart + Nguyen + Yan) + CelVivo ApS co-authored reproducibility (Aiello) + vascularized lung/gut (Miao); 4 of 5 are brain organoids + 1 is vascularized lung/gut (Miao companion to the 2026-08-08 Miao 2025 v2 deep-read); the cluster did NOT receive the `9aa2af4c` vendor-mapping retrofit commit (no companion retrofit commit this cluster); carried forward from the 2026-08-31T18:09Z fetch through the 11-day vault-silence period. Combined with the 2026-08-23/24 + 2026-08-24/25 bursts = **15 LDR files in 8 calendar days** |
 | **Latest uncommitted artifacts (2026-08-13 → 2026-09-29, multi-file, unchanged across the 2026-08-26 → 2026-09-29 fetches)** | `04-Literature/Deep-Reads/Review/zhou2023_computer_vision_microfluidics.md` (carry-forward untracked from 2026-08-13, now at **48-day carry-forward** at the 2026-09-29 fetch — file mtime `2026-08-11 16:31:54 +0800` so mtime-based carry-forward is 48 days; first-observation-date-based carry-forward is 47 days; **structural signal confirmed as one-off** per `/sources/git-repo.md` Notable-entity entry — 47 consecutive fetches silent on the file; the entry remains a stale / not recurring carry-forward note) + **2 prior untracked directories added at the 2026-08-17 fetch**, still-uncommitted at the 2026-09-29 fetch (**43-day carry-forward** each — was 42-day at the 2026-09-28 fetch, 41-day at the 2026-09-27 fetch, 40-day at the 2026-09-26 fetch, 39-day at the 2026-09-25 fetch, 38-day at the 2026-09-24 fetch, 37-day at the 2026-09-23 fetch, 36-day at the 2026-09-22 fetch, 35-day at the 2026-09-21 fetch, 34-day at the 2026-09-20 fetch, 33-day at the 2026-09-19 fetch, 32-day at the 2026-09-18 fetch, 31-day at the 2026-09-17 fetch, 30-day at the 2026-09-16 fetch, 27-day at the 2026-09-13 fetch, 25-day at the 2026-09-11 fetch, 24-day at the 2026-09-09 fetch, 23-day at the 2026-09-08 fetch, 22-day at the 2026-09-07 fetch, 21-day at the 2026-09-06 fetch, 20-day at the 2026-09-05 fetch, 19-day at the 2026-09-04 fetch, 18-day at the 2026-09-03 fetch, 17-day at the 2026-09-02 fetch, 16-day at the 2026-09-01 fetch, 15-day at the 2026-08-31 fetch, 14-day at the 2026-08-30 fetch, 13-day at the 2026-08-29 fetch, 12-day at the 2026-08-28 fetch, 11-day at the 2026-08-27 fetch, 10-day at the 2026-08-26 fetch): `celvivo_commercial/1331651_20260630_131201.pdf` (6-30 quote PDF migrated into new folder; **confirmed one-off at 2026-08-28 fetch** carrying forward unchanged at 2026-08-29 + 2026-08-30 + 2026-08-31 + 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 + 2026-09-10 + 2026-09-11 + 2026-09-12 + 2026-09-13 + 2026-09-14 + 2026-09-15 + 2026-09-16 + 2026-09-17 + 2026-09-18 + 2026-09-19 + 2026-09-20 + 2026-09-21 + 2026-09-22 + 2026-09-23 + 2026-09-24 + 2026-09-25 + 2026-09-26 + 2026-09-27 + 2026-09-28 + **2026-09-29**) + `templates/类器官IRB申请清单.md` (180-line IRB application checklist derived from Guo 2026; Robin's first customer-facing template produced from a single deep-read — see the new Templates subtree below; **confirmed one-off at 2026-08-28 fetch** carrying forward unchanged at 2026-08-29 + 2026-08-30 + 2026-08-31 + 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 + 2026-09-10 + 2026-09-11 + 2026-09-12 + 2026-09-13 + 2026-09-14 + 2026-09-15 + 2026-09-16 + 2026-09-17 + 2026-09-18 + 2026-09-19 + 2026-09-20 + 2026-09-21 + 2026-09-22 + 2026-09-23 + 2026-09-24 + 2026-09-25 + 2026-09-26 + 2026-09-27 + 2026-09-28 + **2026-09-29**) + **1 new untracked directory added at the 2026-08-24 fetch** — `deepread_40240593/` (7 subdirs: 5 PMID-named `deepread_<PMID>/` + 2 slug-named `deepread_brain_organoid_fluid/` + `deepread_shear_stress_cs_os/` that exactly map to the Aiello + CelVivo App Note papers; the new directory is Robin's LDR pipeline intermediate-artifact workspace, see `/sources/git-repo.md` Notable-entity § "deepread_40240593/ pipeline workspace"; **36-day carry-forward** at 2026-09-29, directory mtime unchanged since 2026-08-24 16:31 +0800, the working-folder pipeline hypothesis continues to weaken — the absence of mtime movement across the 2026-08-25 + 2026-08-26 + 2026-08-27 + 2026-08-28 + 2026-08-29 + 2026-08-30 + 2026-08-31 + 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 + 2026-09-10 + 2026-09-11 + 2026-09-12 + 2026-09-13 + 2026-09-14 + 2026-09-15 + 2026-09-16 + 2026-09-17 + 2026-09-18 + 2026-09-19 + 2026-09-20 + 2026-09-21 + 2026-09-22 + 2026-09-23 + 2026-09-24 + 2026-09-25 + 2026-09-26 + 2026-09-27 + 2026-09-28 + **2026-09-29** fetches (35 consecutive silent fetches, plus the 2026-08-31 burst + the 2026-09-10 + 2026-09-11 resumption did NOT route through `deepread_<slug>/` working folders, **36 fetches silent on directory mtime**) suggests the pipeline may have been abandoned, formalized differently, or batched without intermediate commit) |
 ### Vault navigation index (top-level folders)
@@ -93,34 +88,24 @@ Snapshot from [`/sources/git-repo.md`](/sources/git-repo.md) (last fetch 2026-09
 | Subfolder | .md count | Vendor / scope |
 | --- | ---: | --- |
-| `Organoid/` | 661 (+2 from 2026-08-16 — Quintard 2024 Nat Commun microfluidic vascularized organoid chip + Guo 2026 Front Cell Dev Biol organoid ethics systematic review) | broad organoid literature |
+| `Organoid/` | 659 | broad organoid literature |
 | `Celvivo/` | 142 | CelVivo vendor + CelVivo-adjacent papers |
 | `3Brain/` | 136 | 3Brain vendor + 3Brain-adjacent papers |
 | `Cellink/` | 129 | Cellink vendor + Cellink-adjacent papers |
 | `Organoid-List/` | 51 | curated organoid reading lists |
 | `Product-Reports/` | 38 | vendor product reports |
 | `04-Literature/Deep-Reads/` root | +6 from 2026-08-23/24 + 2026-09-10 single-shot LDR bursts (CelVivo App Note + Aiello + Tian + Kim + Ajongbolo from 2026-08-23/24 + **Tomas 2026 HGSC carboplatin/PARPi spheroid+organoid from the 2026-09-10 vault commit `1fd63019`** — Western University; **0 vendor callouts**) — **non-standard pattern** vs prior per-vendor subfolder discipline; **2026-09-13T18:08Z fetch observed 1 working-tree modification** at `MOCs/MOC-类器官与3D培养.md` (mtime 2026-09-13 11:55:42 +0800) — Robin actively editing MOC index but not yet committed; the MOC working-tree modification is the first vault-side artifact change since the 2026-08-31 burst |
 | `Vascularized-Organoids/` | 2 (NEW 2026-08-25 subfolder — Tevonian + Shen vascularized liver MPS / organoid review) | vascularized organoid (Tevonian primary + Shen review) |
 | `Cardiac-Organoids/` | 1 (NEW 2026-08-25 subfolder — Yang cardiac organoid review) | cardiac organoid |
 | `Skin-Organoids/` | 1 (NEW 2026-08-25 subfolder — Zhai 3D skin pemphigus) | autoimmune dermatology + 3D skin (net-new application domain) |
 | `CelVivo/` (capital-V, parallel to lowercase `Celvivo/`) | 5 (NEW 2026-08-31 subfolder — `stewart-2023-ba5-xbb-neurotropic-brain-organoids.md` + `aiello-2025-brain-organoid-reproducibility.md` + `nguyen-2024-jev-g4-2022-australia-brain-organoids.md` + `miao-2025-vascularized-lung-gut-organoids.md` + `yan-2024-tmem106b-sars-cov2-ace2-independent.md`; all 5 single-shot LDR entries committed 2026-08-31 13:05-13:42 +0800; **4 of 5 are brain organoids** for viral-neurotropism modeling (QIMR Berghofer Suhrbier/Rawle research line) + **1 is vascularized lung/gut** (Miao); Robin's first parallel-naming deep-read subfolder convention; subfolder sits at `obsidian-vault/04-Literature/Deep-Reads/CelVivo/` parallel to lowercase `04-Literature/Deep-Reads/Celvivo/`; first LDR cluster **exclusively CelVivo-anchored** since the 2026-08-23/24 + 2026-08-24/25 clusters were partially vendor-distributed) | CelVivo ClinoStar / ClinoReactor brain organoid infectious-disease + reproducibility |
 | `Brain/` | 11 | brain organoid focus |
 | `Brain-Tumor/` | 9 | brain tumor organoid |
 | `Cancer/` | 6 | cancer organoid |
-| `Liver/` | 7 | liver organoid / HepG2 (Liang 2026 4-commit LDR cycle 2026-08-12) |
+| `Liver/` | 6 | liver organoid / HepG2 |
 | `Other/` | 6 | uncategorised |
 | `RegenMed/` | 1 | Ronawk Bio-Block MSC 4-week (added 2026-07-28) |
 | `3Brain MEA/` | 3 | 3Brain HD-MEA papers |
 | `Cardiac/` | 2 | cardiac organoid |
 | `Kidney/` | 2 | kidney organoid |
 | `Retinal/` | 1 | retinal organoid |
 | `Microbioreactor/` | 1 | Rosero 2026 Front Bioeng Biotechnol (added 2026-08-07) |
 | `Cells/` | 1 | Fernandez Vallone 2026 Cells THSDC (added 2026-08-08) |
 | `Review/` | 1 | Zhou 2023 computer vision + microfluidics (added 2026-08-13, **untracked**, **10-day carry-forward** at 2026-08-21 fetch (was 9-day at 2026-08-20) — **8 fetches silent** — structural signal continuing to weaken; **11-day carry-forward** at 2026-08-22 fetch — **9 fetches silent**; **12-day carry-forward** at 2026-08-23 fetch — **10 fetches silent**; **13-day carry-forward** at 2026-08-24 fetch — **11 fetches silent**; **14-day carry-forward** at 2026-08-25 fetch — **12 fetches silent**; **15-day carry-forward** at 2026-08-26 fetch — **13 fetches silent**; **16-day carry-forward** at 2026-08-27 fetch — **14 fetches silent** — **confirmed one-off interpretation at 2026-08-27 fetch** per the parallel `Review/` downgrade in `/sources/git-repo.md`; **17-day carry-forward** at 2026-08-28 fetch — **15 fetches silent** — **demoted to "stale / not recurring" carry-forward note** at the 2026-08-28 fetch; **18-day carry-forward** at 2026-08-29 fetch — **16 fetches silent** — carries forward unchanged at the 2026-08-29 fetch, the 2026-08-28 demotion still standing; **19-day carry-forward** at 2026-08-30 fetch — **17 fetches silent** — carries forward unchanged at the 2026-08-30 fetch, the 2026-08-28 demotion still standing; **20-day carry-forward** at 2026-08-31 fetch — **18 fetches silent** — carries forward unchanged at the 2026-08-31 fetch, the 2026-08-28 demotion still standing; **21-day carry-forward** at 2026-09-01 fetch — **19 fetches silent** — carries forward unchanged at the 2026-09-01 fetch, the 2026-08-28 demotion still standing; **22-day carry-forward** at 2026-09-02 fetch — **20 fetches silent** — carries forward unchanged at the 2026-09-02 fetch, the 2026-08-28 demotion still standing; **23-day carry-forward** at 2026-09-03 fetch — **21 fetches silent** — carries forward unchanged at the 2026-09-03 fetch, the 2026-08-28 demotion still standing; **24-day carry-forward** at 2026-09-04 fetch — **22 fetches silent** — carries forward unchanged at the 2026-09-04 fetch, the 2026-08-28 demotion still standing; **25-day carry-forward** at 2026-09-05 fetch — **23 fetches silent** — carries forward unchanged at the 2026-09-05 fetch, the 2026-08-28 demotion still standing; **26-day carry-forward** at 2026-09-06 fetch — **24 fetches silent** — carries forward unchanged at the 2026-09-06 fetch, the 2026-08-28 demotion still standing; **27-day carry-forward** at 2026-09-07 fetch — **25 fetches silent** — carries forward unchanged at the 2026-09-07 fetch, the 2026-08-28 demotion still standing; **28-day carry-forward** at 2026-09-08 fetch — **26 fetches silent** — carries forward unchanged at the 2026-09-08 fetch, the 2026-08-28 demotion still standing; **29-day carry-forward** at 2026-09-09 fetch — **27 fetches silent** — carries forward unchanged at the 2026-09-09 fetch, the 2026-08-28 demotion still standing; **30-day carry-forward** at 2026-09-11 fetch — **28 fetches silent** — carries forward unchanged at the 2026-09-11 fetch, the 2026-08-28 demotion still standing; **31-day carry-forward** at 2026-09-12 fetch — **29 fetches silent** — carries forward unchanged at the 2026-09-12 fetch; **32-day carry-forward** at 2026-09-13 fetch — **30 fetches silent** — carries forward unchanged at the 2026-09-13 fetch, the 2026-08-28 demotion still standing; entry is a stale carry-forward note; **35-day carry-forward** at the 2026-09-16T18:18Z fetch — **33 fetches silent** — carries forward unchanged at the 2026-09-14 + 2026-09-15 + **2026-09-16** fetches, the 2026-08-28 demotion still standing; entry is a stale carry-forward note; **38-day carry-forward** at the 2026-09-19T18:04Z fetch — **36 fetches silent** — carries forward unchanged at the 2026-09-17 + 2026-09-18 + **2026-09-19** fetches, the 2026-08-28 demotion still standing; entry is a stale carry-forward note; **39-day carry-forward** at the 2026-09-20T18:07Z fetch — **37 fetches silent** — carries forward unchanged at the 2026-09-20 fetch, the 2026-08-28 demotion still standing; entry is a stale carry-forward note; **40-day carry-forward** at the 2026-09-21T18:17Z fetch — **38 fetches silent** — carries forward unchanged at the 2026-09-21 fetch, the 2026-08-28 demotion still standing; entry is a stale carry-forward note; **41-day carry-forward** at the 2026-09-22T18:08Z fetch — **39 fetches silent** — carries forward unchanged at the 2026-09-22 fetch, the 2026-08-28 demotion still standing; entry is a stale carry-forward note; **42-day carry-forward** at the 2026-09-23T18:10Z fetch — **40 fetches silent** — carries forward unchanged at the 2026-09-23 fetch, the 2026-08-28 demotion still standing; entry is a stale carry-forward note; **43-day carry-forward** at the 2026-09-24T18:07Z fetch — **41 fetches silent** — carries forward unchanged at the 2026-09-24 fetch, the 2026-08-28 demotion still standing; entry is a stale carry-forward note; **4Line truncated
 | `Templates/` | 1 | `类器官IRB申请清单.md` v1.0 (2026-08-16, derived from Guo 2026 ethics deep-read, **untracked**; first customer-facing template produced from a single deep-read; **5-day carry-forward** at 2026-08-21 fetch — was 4-day at 2026-08-20; **6-day carry-forward** at 2026-08-22 fetch; **7-day carry-forward** at 2026-08-23 fetch; **8-day carry-forward** at 2026-08-24 fetch; **9-day carry-forward** at 2026-08-25 fetch; **10-day carry-forward** at 2026-08-26 fetch; **11-day carry-forward** at 2026-08-27 fetch — **approaching confirmed one-off interpretation alongside the `Review/` entry**; **12-day carry-forward** at 2026-08-28 fetch — **11 fetches silent** — **now confirmed one-off alongside the `Review/` + `CelVivo-commercial/` entries** at the 2026-08-28 fetch; **13-day carry-forward** at 2026-08-29 fetch — **12 fetches silent** — carries forward unchanged at the 2026-08-29 fetch, the 2026-08-28 confirmation still standing; **14-day carry-forward** at 2026-08-30 fetch — **13 fetches silent** — carries forward unchanged at the 2026-08-30 fetch, the 2026-08-28 confirmation still standing; **15-day carry-forward** at 2026-08-31 fetch — **14 fetches silent** — carries forward unchanged at the 2026-08-31 fetch, the 2026-08-28 confirmation still standing; **16-day carry-forward** at 2026-09-01 fetch — **15 fetches silent** — carries forward unchanged at the 2026-09-01 fetch, the 2026-08-28 confirmation still standing; **17-day carry-forward** at 2026-09-02 fetch — **16 fetches silent** — carries forward unchanged at the 2026-09-02 fetch, the 2026-08-28 confirmation still standing; **18-day carry-forward** at 2026-09-03 fetch — **17 fetches silent** — carries forward unchanged at the 2026-09-03 fetch, the 2026-08-28 confirmation still standing; **19-day carry-forward** at 2026-09-04 fetch — **18 fetches silent** — carries forward unchanged at the 2026-09-04 fetch, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **20-day carry-forward** at 2026-09-05 fetch — **19 fetches silent** — carries forward unchanged at the 2026-09-05 fetch, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **21-day carry-forward** at 2026-09-06 fetch — **20 fetches silent** — carries forward unchanged at the 2026-09-06 fetch, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **22-day carry-forward** at 2026-09-07 fetch — **21 fetches silent** — carries forward unchanged at the 2026-09-07 fetch, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **23-day carry-forward** at 2026-09-08 fetch — **22 fetches silent** — carries forward unchanged at the 2026-09-08 fetch, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **24-day carry-forward** at 2026-09-09 fetch — **23 fetches silent** — carries forward unchanged at the 2026-09-09 fetch, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **25-day carry-forward** at 2026-09-11 fetch — **24 fetches silent** — carries forward unchanged at the 2026-09-11 fetch, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **30-day carry-forward** at the 2026-09-16T18:18Z fetch — **30 fetches silent** — carries forward unchanged at the 2026-09-12 + 2026-09-13 + 2026-09-14 + 2026-09-15 + **2026-09-16** fetches, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **33-day carry-forward** at the 2026-09-19T18:04Z fetch — **33 fetches silent** — carries forward unchanged at the 2026-09-17 + 2026-09-18 + **2026-09-19** fetches, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **34-day carry-forward** at the 2026-09-20T18:07Z fetch — **34 fetches silent** — carries forward unchanged at the 2026-09-20 fetch, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **35-day carry-forward** at the 2026-09-21T18:17Z fetch — **35 fetches silent** — carries forward unchanged at the 2026-09-21 fetch, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **36-day carry-forward** at the 2026-09-22T18:08Z fetch — **36 fetches silent** — carries forward unchanged at the 2026-09-22 fetch, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **37-day carry-forward** at the 2026-09-23T18:10Z fetch — **37 fetches silent** — carries forward unchanged at the 2026-09-23 fetch, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **38-day carry-forward** at the 2026-09-24T18:07Z fetch — **38 fetches silent** — carries forward unchanged at the 2026-09-24 fetch, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **39-day carry-forward** at the 2026-09-25T18:17Z fetch — **39 fetches silent** — carries forward unchanged at Line truncated
 | `CelVivo-commercial/` | 1 | `1331651_20260630_131201.pdf` (2026-06-30 quote PDF migrated into new folder 2026-08-17, **untracked**; **5-day carry-forward** at 2026-08-21 fetch — was 4-day at 2026-08-20; **6-day carry-forward** at 2026-08-22 fetch; **7-day carry-forward** at 2026-08-23 fetch; **8-day carry-forward** at 2026-08-24 fetch; **9-day carry-forward** at 2026-08-25 fetch; **10-day carry-forward** at 2026-08-26 fetch; **11-day carry-forward** at 2026-08-27 fetch — **approaching confirmed one-off interpretation alongside the `Review/` + `Templates/` entries**; **12-day carry-forward** at 2026-08-28 fetch — **11 fetches silent** — **now confirmed one-off alongside the `Review/` + `Templates/` entries** at the 2026-08-28 fetch; **13-day carry-forward** at 2026-08-29 fetch — **12 fetches silent** — carries forward unchanged at the 2026-08-29 fetch, the 2026-08-28 confirmation still standing; **14-day carry-forward** at 2026-08-30 fetch — **13 fetches silent** — carries forward unchanged at the 2026-08-30 fetch, the 2026-08-28 confirmation still standing; **15-day carry-forward** at 2026-08-31 fetch — **14 fetches silent** — carries forward unchanged at the 2026-08-31 fetch, the 2026-08-28 confirmation still standing; **16-day carry-forward** at 2026-09-01 fetch — **15 fetches silent** — carries forward unchanged at the 2026-09-01 fetch, the 2026-08-28 confirmation still standing; **17-day carry-forward** at 2026-09-02 fetch — **16 fetches silent** — carries forward unchanged at the 2026-09-02 fetch, the 2026-08-28 confirmation still standing; **18-day carry-forward** at 2026-09-03 fetch — **17 fetches silent** — carries forward unchanged at the 2026-09-03 fetch, the 2026-08-28 confirmation still standing; **19-day carry-forward** at 2026-09-04 fetch — **18 fetches silent** — carries forward unchanged at the 2026-09-04 fetch, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **20-day carry-forward** at 2026-09-05 fetch — **19 fetches silent** — carries forward unchanged at the 2026-09-05 fetch, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **21-day carry-forward** at 2026-09-06 fetch — **20 fetches silent** — carries forward unchanged at the 2026-09-06 fetch, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **22-day carry-forward** at 2026-09-07 fetch — **21 fetches silent** — carries forward unchanged at the 2026-09-07 fetch, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **23-day carry-forward** at 2026-09-08 fetch — **22 fetches silent** — carries forward unchanged at the 2026-09-08 fetch, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **24-day carry-forward** at 2026-09-09 fetch — **23 fetches silent** — carries forward unchanged at the 2026-09-09 fetch, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **25-day carry-forward** at 2026-09-11 fetch — **24 fetches silent** — carries forward unchanged at the 2026-09-11 fetch, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **26-day carry-forward** at 2026-09-12 fetch — **25 fetches silent** — carries forward unchanged at the 2026-09-12 fetch; **27-day carry-forward** at 2026-09-13 fetch — **26 fetches silent** — carries forward unchanged at the 2026-09-13 fetch, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **30-day carry-forward** at the 2026-09-16T18:18Z fetch — **30 fetches silent** — carries forward unchanged at the 2026-09-14 + 2026-09-15 + **2026-09-16** fetches, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **33-day carry-forward** at the 2026-09-19T18:04Z fetch — **33 fetches silent** — carries forward unchanged at the 2026-09-17 + 2026-09-18 + **2026-09-19** fetches, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **34-day carry-forward** at the 2026-09-20T18:07Z fetch — **34 fetches silent** — carries forward unchanged at the 2026-09-20 fetch, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **35-day carry-forward** at the 2026-09-21T18:17Z fetch — **35 fetches silent** — carries forward unchanged at the 2026-09-21 fetch, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **36-day carry-forward** at the 2026-09-22T18:08Z fetch — **36 fetches silent** — carries forward unchanged at the 2026-09-22 fetch, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **37-day carry-forward** at the 2026-09-23T18:10Z fetch — **37 fetches silent** — carries forward unchanged at the 2026-09-23 fetch, the 2026-08-28 confirmation still standing; entry is a stale carry-forward note; **38-day carry-forward** at the 2026-09-24T18:07Z fetch — **38 fetches Line truncated
-Total ≈ 1,211 deep-read notes on `main` (+5 new LDR files from the 2026-08-31 CelVivo-cluster on top of +4 from the 2026-08-24/25 cluster + +5 from the 2026-08-23/24 single-shot LDR burst + +2 from the 2026-08-16 Quintard 2024 + Guo 2026 clusters; the 5th 2026-08-25 commit `9aa2af4c` is an in-place `M` touch on Tevonian + Yang files, not a new file). The 4 vendor subfolders (Celvivo / 3Brain / Cellink / Organoid) cover the canonical product KB per the wiki goal focus areas. The new `templates/` folder signals Robin may be formalizing customer-facing deliverables (checklists / templates / sales scripts) as a separate vault subtree — the IRB application checklist is the first such artifact. The 2026-08-31 cluster creates the **NEW `CelVivo/` (capital-V) parallel subfolder** — Robin's first parallel-naming deep-read subfolder convention.
+Total ≈ 1,202 deep-read notes. The 4 vendor subfolders (Celvivo / 3Brain / Cellink / Organoid) cover the canonical product KB per the wiki goal focus areas.
 ## Literature deep-read (LDR) pipeline
@@ -161,7 +146,8 @@ From [`/sources/ldr-report-template.md`](/sources/ldr-report-template.md) (Robin
 | 3. 9 项强制 + 创新点/局限性/学术启示 3 段 | 7-27 教训 (2 篇缺 3 段) | 模板 §3 |
 | 4. SeaFile URL hostname `fb.biokingdom.top` | 7-27 教训 (5 URL 错) | 验证 share-link 真能开 |
 | 5. NocoDB v1 + JSON body (范本 v2 失败 3 次) | 7-27 Tasevska 入库 | `POST /api/v1/db/data/wzg1wtad/p2z4g0s687axyvu/{table_id}` |
-| 6. 3 张真图 `![]()` (SeaFile URL), 不**只**文字图说啥 | 7-27 教训 | markdown image syntax (`alt text` + parenthesized URL) |
+<!-- openwiki: broken internal link [url] file "url" does not exist. Fix the href or restore the target, then delete this comment. -->
 | 6. 3 张真图 `![]()` (SeaFile URL), 不**只**文字图说啥 | 7-27 教训 | `!\[alt\](url)` markdown |
 | 7. 报告路径 `journal-year-topic` (4-27 SOP 范本) | 7-27 教训 | `ejps-2025-hctz-sse-3d-printing` 风格 |
 | 8. 精简 4 步 vs 完整 8 步按 Robin 信号自动判断 | 7-27 实战 | 模板 §2 |
@@ -186,31 +172,13 @@ From [`/sources/ldr-report-template.md`](/sources/ldr-report-template.md) (Robin
 | Hodge 2025 RegenMed | Ronawk Bio-Block (KB 0 命中) | `04-Literature/Deep-Reads/RegenMed/2026-07-28_Hodge_2025_RegenMed_MSC_3D_Bio-Block.md` | (not yet synthesized to `/sources/`) |
 | Lee 2025 Front Vet Sci | (no vendor) | `04-Literature/Deep-Reads/Other/2026-07-28_Lee_2025_FrontVetSci_canine_MSC_3D_spheroid.md` | (not yet synthesized) |
 | Parate 2020 SCRT | (no vendor) | `04-Literature/Deep-Reads/Other/2026-07-28_Parate_2020_SCRT_PEMF_MSC_paracrine_cartilage.md` | (not yet synthesized) |
 | Sharma 2026 Cell Stem Cell (2026-08-08 flywheel-sync) | 3Brain + CelVivo adjacent | `/home/ldw/workspace/retinal_organoid_deep_read_2026-08-07.md` | [`/sources/literature-sharma-2026-cell-stem-cell-vascularized-retinal-organoid-rgc-deepread.md`](/sources/literature-sharma-2026-cell-stem-cell-vascularized-retinal-organoid-rgc-deepread.md) |
 | Miao 2025 Cell v2 (2026-08-08 flywheel-sync) | CelVivo (ClinoStar rating 5) | `/home/ldw/workspace/Miao2025_Cell_v2.md` | [`/sources/literature-miao-2025-cell-vascularization-v2-deepread.md`](/sources/literature-miao-2025-cell-vascularization-v2-deepread.md) |
 | Liu 2026 Nat Biomed Eng (2026-08-08 flywheel-sync) | 3Brain (HD-MEA rating 5) + Cellink (microlattice rating 5) | `/home/ldw/workspace/Liu2026_NBME_shape_conformal_organoid.md` | [`/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md`](/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md) |
 | Quintard 2024 Nat Commun (2026-08-16 vault LDR cluster) | CelVivo (ClinoStar rating 3 upstream) + Mimetas OrganoPlate (rating 4 direct) + Emulate Organ-Chip (rating 3) | `obsidian-vault/Literature/Deep-Reads/Organoid/quintard_2024_vasorganoid_chip.md` | (not yet synthesized to `/sources/`) |
 | Guo 2026 Front Cell Dev Biol (2026-08-16 vault LDR cluster) | CelVivo (ClinoStar rating 4 clinical-translation IRB) + Mimetas OrganoPlate (rating 4 co-culture ethics) + Emulate Organ-Chip (rating 3) | `obsidian-vault/Literature/Deep-Reads/Organoid/guo_2026_organoid_ethical_review.md` | (not yet synthesized to `/sources/`; derived customer-facing template at `templates/类器官IRB申请清单.md` v1.0) |
-## Recent 30-day research output (mtime 2026-06-16 → 2026-08-12)
+## Recent 30-day research output (mtime 2026-06-16 → 2026-07-28)
 From [`/sources/literature.md`](/sources/literature.md) last sync, broken out by vendor and date:
 | Date | DOI / slug | Vendor | Topic |
 | --- | --- | --- | --- |
 | 2026-08-16 | **Quintard 2024 Nat Commun + Guo 2026 Front Cell Dev Biol 7-commit LDR cluster** (commits `0fc8db24` + `290e9635` + `24c713de` + `4073abf4` Quintard + `2e6f5989` + `00f824f2` + `a4fa5a32` Guo) | **CelVivo adjacent + Mimetas OrganoPlate ⭐⭐⭐⭐ + Emulate Organ-Chip ⭐⭐⭐** (Quintard) / **CelVivo ClinoStar ⭐⭐⭐⭐ + Mimetas OrganoPlate ⭐⭐⭐⭐ + Emulate Organ-Chip ⭐⭐⭐** (Guo) | Quintard C et al. (2024) A microfluidic platform integrating functional vascularized organoids-on-chip (Nat Commun DOI 10.1038/s41467-024-45710-4, Wiki ID 1719/1720/1722, NocoDB Id 3297; 10 通道并行微流控 + hiPSC-BVO 30 天功能性灌注培养 + 跨类器官验证 [间充质球体 / BVO / 胰岛球体 / 肺类器官]; 血管层级化 37 µm 上游动脉-静脉 + 8 µm BVO 毛细管, 壁剪切 27-2000 s⁻¹, 完美匹配人体毛细血管生理范围 50-1900 s⁻¹) + Guo Z & Zhang N (2026) Ethical review key considerations for organoid applications in biomedical research—a systematic review (Front Cell Dev Biol DOI 10.3389/fcell.2026.1721946, Wiki ID 1724, NocoDB Id 3298; 嘉兴市第一医院 + 嘉兴大学医学院视角; 类器官研究 IRB / 伦理审查 7 大强制要点系统综述 [样本来源/知情同意/数据隐私/共培养主体性/3R 动物福利/跨境监管/长期保存与终止使用] + 中国《人类遗传资源管理条例》+ 国际 ISSCR/GDPR/HIPAA 多国对照表). **Robin translated Guo 2026 into a customer-facing IRB application checklist template** (`templates/类器官IRB申请清单.md` v1.0 180 lines) — first customer-facing template produced from a single deep-read. |
 | 2026-08-25 | **SECOND consecutive single-day 5-paper LDR burst** (commits `089177a7` Tevonian + `583859a8` Yang + `9aa2af4c` vendor-mapping retrofit + `5907cdfc` Shen + `9d4767c7` Zhai) | **5-vendor product mapping retrofit on Tevonian + Yang** (CelVivo ClinoStar/ClinoReactor + Cellink BIO X + Mimetas OrganoPlate + 3Brain HD-MEA + FemtoBiomed CellShot) | **Tevonian 2026 Nat Commun vascularized liver MPS** (PMID 41634021, Wiki.js 1749; PDMS+fibrin+原代肝+HUVEC vascularized liver MPS, 14天 IR modeling, 单核细胞 infiltration enhancement; **first file in new Vascularized-Organoids/ subfolder**) + **Yang 2026 Stem Cell Res Ther cardiac organoid review** (PMID 41963991, Wiki.js 1750; 复旦 + InnoStar comprehensive review of hPSC cardiac organoid generation methods (FGF/PI3K/Wnt/BMP/Activin/RA 五大信号通路) + maturation protocols + disease modeling + regenerative medicine; **first file in new Cardiac-Organoids/ subfolder** — first new subfolder explicitly for an application-domain cluster) + **post-publish vendor-mapping retrofit commit `9aa2af4c`** on Tevonian + Yang (adds 5-vendor mapping table + 净化 Robin mentions; **first post-publish vendor-mapping retrofit step in Robin's LDR pipeline**, iterates the 8-step SOP to a 9-step SOP) + **Shen 2026 Chin Med J vascularized organoids review** (PMID 42268296, Wiki.js 1751; 华西医院 Chinese-language peer-reviewed systematic review of vascularized organoids 4 大策略 (共培养 + 转录因子诱导 + 微流控 + 生物材料支架) + 12 维对比 + 三大未来方向; second file in Vascularized-Organoids/ subfolder) + **Zhai 2026 Sci Adv 3D skin pemphigus** (PMID 41512055, Wiki.js 1752; 3D 打印 + 自组织 multilayer vascularized skin model for 天疱疮 autoimmune disease modeling + EGFR-targeted therapy + ML-assisted drug screening; **first file in new Skin-Organoids/ subfolder** — **net-new application domain** autoimmune dermatology + 3D skin). **3 NEW `04-Literature/Deep-Reads/` subfolders** created in a single day: `Vascularized-Organoids/` + `Cardiac-Organoids/` + `Skin-Organoids/` (Robin expands the deep-read folder taxonomy from ~19 → ~22, returning to per-vendor / per-application-domain subfolder discipline after the 2026-08-23/24 root-level non-standard pattern). **Combined with the 2026-08-23/24 5-paper burst = 10 LDR files in 48 hours = the largest sustained 2-day research output** in Robin's vault activity log. |
 | 2026-08-31 | **THIRD consecutive single-day 5-paper LDR burst** (commits `eb24ab72` Stewart + `030f31ed` Aiello + `fad7e21e` Nguyen + `4fca0123` Miao + `391e4713` Yan) — **all 5 exclusively CelVivo-anchored** (QIMR Berghofer Suhrbier/Rawle viral-neurotropism line + CelVivo ApS co-authored reproducibility + vascularized lung/gut) | **CelVivo ClinoStar / ClinoReactor** (direct platform validation across 4 brain organoid infectious-disease papers + 1 vascularized lung/gut paper; 1 paper — Aiello 2025 — has CelVivo ApS as a co-author affiliation, validating the ClinoStar/ClinoReactor platform as a reproducibility-benchmarking standard) | **Stewart 2023 Front Microbiol SARS-CoV-2 omicron BA.5/XBB neurotropic brain organoids** (DOI 10.3389/fmicb.2023.1320856; QIMR Berghofer Medical Research Institute + University of Queensland; K18-hACE2 mice + human brain organoids; MA1 infection cell count higher; **first file in new `CelVivo/` capital-V subfolder**) + **Aiello 2025 EMBO reports reproducible brain organoids** (DOI 10.1038/s44319-025-00619-x; 洛桑大学 + 罗马 Tor Vergata 大学 + 西北大学 (南非) + **CelVivo ApS (丹麦) co-author**; controlled fluid dynamics brain organoid reproducibility; CV <15% multi-batch + multi-cell-line) + **Nguyen 2024 npj Viruses JEV G4 2022 Australia brain organoids** (DOI 10.1038/s44298-024-00025-5; QIMR Berghofer + INRAE; JEV genotype 4 isolate characterization) + **Miao 2025 Cell vascularized lung/gut organoids** (DOI 10.1016/j.cell.2025.05.041; co-differentiation mesoderm+endoderm for organotypic vascularization; **companion to the 2026-08-08 flywheel-sync Miao 2025 v2 deep-read**) + **Yan 2024 Cell Reports TMEM106B SARS-CoV-2 ACE2-independent brain organoids** (DOI 10.1016/j.celrep.2024.114921; QIMR Berghofer; CRISPR 筛选鉴定 TMEM106B/硫酸乙酰肝素/内吞介导 ACE2 非依赖进入; 人源皮层脑类器官 CelVivo ClinoStar; MA1 神经毒力更强 in vitro but in vivo not consistent). **5 papers all single-shot LDR entries** (no v2/v3 SOP rewrite cycles this cluster); cluster does **NOT receive the `9aa2af4c` post-publish vendor-mapping retrofit commit** (no companion retrofit this cluster, unlike the 2026-08-24/25 cluster which had `9aa2af4c` as the 3rd of 5 commits). **1 NEW `04-Literature/Deep-Reads/` subfolder created**: `CelVivo/` (capital-V, parallel to existing lowercase `Celvivo/` subfolder) at `obsidian-vault/04-Literature/Deep-Reads/CelVivo/` — **Robin's first parallel-naming deep-read subfolder convention** (subfolder taxonomy from ~22 → ~23 in 8 calendar days). **Combined with 2026-08-23/24 + 2026-08-24/25 = 15 LDR files in 8 calendar days = the largest sustained 8-day research output** in Robin's vault activity log. Ends the 5-day vault silence streak from the 2026-08-24/25 burst. |
 | 2026-08-24 | **First 5-paper LDR burst in 24-hour window** (commits `ad4abcde` Ajongbolo + `5f02489a` Kim + `40b357b8` Tian + `f2118a62` Aiello + `fb017e4f` CelVivo App Note) | **CelVivo-aligned (3) + 3Brain-adjacent (1) + cardiac-epicardium (1)** | Ajongbolo 2025 Cells brain organoid review (PMID DOI 10.3390/cells14110842, Wiki.js 1743; canonical brain organoid + assembloid review with 3-tier taxonomy + 4-class characterization methodology) + Kim 2025 Nat Commun EGaIn liquid-metal 3D MEA (DOI 10.1038/s41467-024-55752-3, Wiki.js 1744; 25-310 µm pillar height, 14 µm diameter, magnetically reshapeable; 3Brain HD-MEA adjacent) + Tian 2025 Nat Commun hiPSC epicardium mTOR maturation (DOI 10.1038/s41467-025-60934-8, Wiki.js 1745; Torin1 dual mTORC1/2 inhibition drives mature epicardium via YBX3/MAFF TFs) + Aiello & Bagni 2025 biorxiv Rotating Chamber brain organoid CFD (Wiki.js 1746; COMSOL CFD < 20 mPa cavity shear stress, cross-organoid-line morphological CV < 15%) + CelVivo App Note 2026 shear stress ClinoStar vs orbital shaker (Wiki.js 1747; head-to-head comparison across HepG2/C3A + Caco-2 + brain organoid — first vendor App Note deep-read). **All 5 files landed at `04-Literature/Deep-Reads/` root** (non-standard pattern vs the prior per-vendor subfolder discipline). Vendor-anchor mapping: 3 CelVivo-aligned (CelVivo App Note + Aiello [ClinoStar-adjacent] + Ajongbolo mentions ClinoStar) + 1 3Brain-adjacent (Kim EGaIn 3D MEA — 3rd next-gen HD-MEA approach alongside Liu 2026 + 3Brain Accura-3D) + 1 cardiac epicardium (Tian mTOR, no vendor callouts). **Largest single-day LDR burst since the 2026-07-29 Parate / Lee / Hodge cluster**. |
 | 2026-08-12 | **Liang 2026 liver organoid fibrosis platform 4-commit LDR cycle** (commits `e542c977` + `8699a154` + `aacba7aa` + `297f106d`) | **CelVivo (ClinoStar rating 5 + ClinoReactor rating 5)** | Liang Y et al. (2026) A robust mouse liver organoid platform enables sustained multicellular maturation and fibrosis modeling from a single tissue sample (Sci Rep DOI 10.1038/s41598-026-42990-2, PMID 41857098; Wiki.js Id 1716, NocoDB Id 770; 3 轨道 Hep-Orgs + Cho-Orgs + HSC 同步分离; DAPT+Dex P1-P10 长程稳定成熟 [ALB/PAS/LDL/CYP 跨代保持]; TGFβ 激活 qHSC → aHSC [Acta2/Col1a1 上调]; aHSC 共培养诱导 Hep-Orgs EMT [Snail/Twist/Vimentin↑; ALB/CK8↓; Lgr5/EpCAM↓; Ki67↓] = 体外肝纤维化模型) — page 946 9 项 SOP 重写版 + page 934 修齐 标杆; 7/7 Ollama qwen2.5vl 视觉审核通过; SeaFile 7/7 公网 200 验真. First paper whose `related:` field already names `[[MOC-类器官与3D培养]]` (the 2026-08-10 first MOC) on the day of publication. |
 | 2026-08-10 | **Phase A metadata batch + first MOC** (commits `d97b39ed` + `6b717aef` + `3b929c2f`) | (process discipline) | 6 deep-reads received the 6-field frontmatter (doi/journal/year/volume/pages/authors/pmid); first MOC `MOC-类器官与3D培养.md` (95 lines, 沙牛《AI 时代的 Obsidian 公开课》课时 1 pattern) created at `04-Literature/Deep-Reads/MOCs/`; 7 image alt descriptions added on `wang2024-org-on-chip.md`. No new external evidence. |
 | 2026-08-09 | `10.7150/thno.90492` (Wang 2024) | (4 类共性硬件 — Organoid-on-Chip 综述) | Wang H et al. (2024) Human organoids-on-chips for biomedical research and applications (Theranostics 14(2):788-818, PMID 38169573; 7 图覆盖 7 大主题板块) — Wiki.js ID 1700 (v2 - grp:3 ghost page 累加) |
 | 2026-08-08 | `10.3390/cells15110963` (Fernandez Vallone 2026) | (NAMs adjacent, hiPSC brain organoid) | THSDC chemical evaluation platform using hiPSC brain organoids (Cells, v2 5 张真图 + 双 H1; Wiki.js Id 1698) |
 | 2026-08-08 | `10.3389/fbioe.2026.1854988` (Rosero 2026) | CelVivo + Cellink + FemtoBiomed adjacent | Microbioreactor design Mini Review (Front Bioeng Biotechnol; 6× productivity vs T-flask; 4 applications: CAR-T / mAb / iPSC / organoid) |
 | 2026-08-08 | `10.1038/s41551-026-01620-y` (Liu 2026) | 3Brain (HD-MEA rating 5) + Cellink (microlattice rating 5) | Shape-conformal porous framework for full-coverage neural organoid e-phys — Rogers Lab, Nat Biomed Eng |
 | 2026-08-08 | `10.1016/j.cell.2025.05.041` (Miao 2025 v2) | CelVivo (ClinoStar rating 5) | Co-development mesoderm+endoderm for vascularized lung/gut organoids (Cell v2) |
 | 2026-08-08 | `10.1016/j.stem.2025.12.013` (Sharma 2026) | 3Brain (HD-MEA rating 4) + CelVivo (ClinoStar rating 3) | Vascularized retinal organoid RGC survival (Cell Stem Cell) |
 | 2026-08-06 | `10.1038/s41467-024-44732-2` (Parfitt 2024) | CelVivo + 3Brain adjacent | DJ1 LOF midbrain organoid PD model — α-syn via astrocyte lysosomal degradation (Nat Commun, untracked) |
 | 2026-07-29 | Organoids for disease modeling and treatment 2026 综述 (PMID 41545895, PMC12828948) | review | Exp Hematol Oncol 2026 — 190 项临床试验 + 4 大瓶颈 |
 | 2026-07-28 | `10.1080_17460751.2025.2572177` (Hodge 2025) | Ronawk Bio-Block | MSC longevity 4-week comparison |
 | 2026-07-28 | `10.3389/fvets.2025.1500267` (Lee 2025) | (no vendor) | canine adipose MSC 3D spheroid |
@@ -229,18 +197,14 @@ From [`/sources/literature.md`](/sources/literature.md) last sync, broken out by
 By vendor (30-day mtime):
-| Vendor | Most recent | 2026-08-08 / 2026-08-10 / 2026-08-12 / 2026-08-16 additions |
+| Vendor | Most recent |
-| --- | --- | --- |
+| --- | --- |
-| CelVivo | 2026-08-12 (Liang 2026 — ClinoStar rating 5 + ClinoReactor rating 5) | +Liang 2026 (P1-P10 长程成熟 + 单组织 3 轨道分通道灌流 + TGFβ 时间程序精确切换 — liver organoid fibrosis platform), +Miao 2025 v2 (ClinoStar co-differentiation), +Sharma 2026 (ClinoStar rating 3 adjacent), +Liu 2026 (ClinoStar rating 4 adjacent), +Quintard 2024 (CelVivo ClinoStar rating 3 — upstream workflow step: BVO day 0-15 needs rotating-wall suspension culture), +Guo 2026 (CelVivo ClinoStar rating 4 — clinical-translation IRB compliance for 三甲医院 客户) |
+| CelVivo | 2026-07-17 (CS vs OS + Planimetry) |
-| 3Brain | 2026-08-08 (Liu 2026 — HD-MEA rating 5) | +Liu 2026 (shape-conformal framework, next-gen HD-MEA), +Sharma 2026 (HD-MEA rating 4 adjacent), +Shin 2024 (Phase A frontmatter hygiene on existing note), **−3Brain reference removed from Quintard 2024 -v4 (per commit `4073abf4` — "精读 Quintard 2024 -v4 (转发语标题/落款加粗/删3Brain)" was the explicit SOP rule "硬门槛合规修正" cleanup; Quintard is vendor-adjacent CelVivo/Mimetas/Emulate rather than 3Brain territory)** |
+| 3Brain | 2026-07-27 (Raji 2026) |
-| Cellink | 2026-07-27 (Tasevska 2025) | +Liu 2026 (microlattice fabrication rating 5 adjacent), **+Quintard 2024 (microfluidic organ-on-chip adjacent, no direct Cellink rating — but the platform architecture is a candidate cross-sell with Cellink BIO X for vascularized scaffold fabrication)** |
+| Cellink | 2026-07-27 (Tasevska 2025) |
-| Adjacent (no vendor) | 2026-08-08 (Sharma 2026 retinal vascularization) | +Sharma 2026 (retinal organoid application domain) |
+| Adjacent (no vendor) | 2026-07-29 (Organoids 2026 综述) |
 | (Process discipline) | 2026-08-10 (Phase A batch + first MOC) | +6 deep-reads received 6-field frontmatter; +first MOC `MOC-类器官与3D培养.md` created; +7 image alt descriptions on Wang 2024 — no new external evidence |
 | (Subfolder expansion, uncommitted) | 2026-08-13 (new `Review/` subfolder) | +1 untracked file `Review/zhou2023_computer_vision_microfluidics.md` (first review-type subfolder — review papers stream separately from original research) |
 | (Customer-facing template, uncommitted) | 2026-08-16 (new `templates/` subfolder + IRB application checklist v1.0) | +1 untracked file `templates/类器官IRB申请清单.md` 180 lines (Guo 2026 ethics deep-read → IRB checklist template; 7 mandatory points + 5 customer Q&A + China vs International flow + 10 attachments + 7 citations; Robin's first customer-facing template produced from a single deep-read; will route into CelVivo industrial-customers program once committed) |
 | (Commercial quote PDF, untracked) | 2026-08-17 (new `celvivo_commercial/` subfolder) | +1 untracked file `celvivo_commercial/1331651_20260630_131201.pdf` (6-30 quote PDF migrated into a new folder; companion to the existing `05-Documents/Products/Celvivo/Industrial-Customers/` commercial-docs subtree) |
-The pipeline is **vendor-balanced** — CelVivo, 3Brain, Cellink each have a recent deep read, and the 2026-08-08 flywheel-sync adds **3 papers spanning all 3 primary vendors + the retinal organoid application domain** (Sharma), all 3 rated 4-5 on at least one vendor's product line. The 2026-08-10 cluster is **process discipline** (Phase A metadata batch + first MOC creation + Wang 2024 alt-description sample), not new external evidence — the 6 deep-reads already existed on `main`; the 3 commits only normalize their metadata and add a knowledge-graph index layer. The 2026-08-12 cluster adds **net-new external evidence**: Liang 2026 Sci Rep liver organoid fibrosis platform (4-commit LDR cycle on a single paper, CelVivo ClinoStar ⭐⭐⭐⭐ + ClinoReactor ⭐⭐⭐⭐); this is the **first paper on `main` whose `related:` field already names `[[MOC-类器官与3D培养]]` on the day of publication**, confirming the MOC pattern is in active use on real deep-reads (vs the prior 2026-08-10 "MOC `related:` lists future MOCs" framing which was only prospective). The **first entry in the new NocoDB table `Robin_Picked_Papers`** is Liu 2026 (created 2026-08-08 per Robin instruction to capture papers Robin hand-picks / provides outside the regular PubMed triage). The **first MOC** `MOC-类器官与3D培养.md` is the start of a Map-of-Content layer Robin appears to be building (the MOC's own `related:` already names `[[MOC-3Brain-HD-MEA]]` as the next planned MOC). The 2026-08-13 cluster (no vault commits, 1 new untracked file) **adds a new `Review/` subfolder to the deep-read tree** — Robin appears to be expanding the folder taxonomy to separate review-type papers from original-research papers; whether this is a one-off subfolder or the start of a recurring folder pattern is a watchlist item for the next git-repo fetch. **The 2026-08-16 cluster (Quintard 2024 + Guo 2026) is the largest single-window vault delta since the 2026-07-28 / 2026-07-29 cluster** — 7 new vault commits spanning 2 new paper deep-reads, 2 new untracked working-tree directories, and 1 customer-facing sales-ammunition template derived from a single deep-read. The Quintard 2024 microfluidic / organ-on-chip platform (CelVivo ClinoStar upstream + Mimetas OrganoPlate direct competitor + Emulate Organ-Chip) extends Robin's vendor mapping into the organ-on-chip product lane that his portfolio doesn't currently cover; the Guo 2026 organoid ethics systematic review (7 mandatory points + 5 jurisdiction comparison) introduces the IRB / ethics domain to Robin's deep-read set and spawned `templates/类器官IRB申请清单.md` (180 lines, Robin's first customer-facing template) as the canonical "Robin 培训客户 IRB 申请" core material. The new `templates/` + `celvivo_commercial/` directories appear alongside the existing `05-Documents/Products/Celvivo/Industrial-Customers/` commercial-docs subtree — Robin may be formalizing customer-facing deliverables (checklists / templates / sales scripts) as a separate vault subtree. The `Review/zhou2023_computer_vision_microfluidics.md` carry-forward untracked file is still-uncommitted at this fetch (now 4 days past the 2026-08-13 first observation); the watchlist trigger is if it remains uncommitted at the next fetch.
+The pipeline is **vendor-balanced** — CelVivo, 3Brain, Cellink each have a recent deep read, and the broad organoid corpus is sustained by Ronawk Bio-Block, canine MSC, PEMF MSC paracrine, and the 2026 综述.
 ## Sales ammunition pipeline
@@ -254,8 +218,6 @@ Robin maintains a working sales library that consumes LDR output and routes into
 Cross-link to the canonical synthesis: [`/sources/sales-ammunition.md`](/sources/sales-ammunition.md).
 **2026-08-16 addition — `templates/类器官IRB申请清单.md` v1.0** (180 lines, Robin 8-16 实战沉淀, **untracked**; derived from Guo 2026 Front Cell Dev Biol IRB / ethics systematic review — Wiki.js ID 1724, NocoDB Id 3298). The IRB application checklist is **Robin 第一份 customer-facing template produced from a single deep-read** and consists of: (a) **7 强制要点** [样本来源合法性 + 捐赠者知情同意 + 数据隐私与去标识化 + 共培养产物主体性评估 + 动物福利 3R + 跨境监管合规 + 长期保存与终止使用]; (b) **5 customer Q&A** [类器官研究是否要 IRB 申请 / 类器官共培养产品怎么申请 IRB / 类器官跨境研究怎么报 / 3R 原则怎么写 / 类器官 + 免疫细胞共培养 = CAR-T 体外培养, 算不算新生物体]; (c) **China vs International flow comparison table** [中国 2023 新规 vs 美国 Common Rule vs 欧盟 GDPR]; (d) **10 申请附件清单** [IRB 申请表 + 知情同意书 + 研究方案 + DMP + 样本采集机构 IRB 批件 + ...]; (e) **7 引用** [Guo 2026 + ISSCR 2021 + OHRP 2016 + GDPR + 中国 2023 + 中国 2019 + Cambridge 2020]. **Vendor relevance**: CelVivo ClinoStar ⭐⭐⭐⭐ (the 7 mandatory points directly apply to ClinoStar customer IRB submissions; **Robin 推广 ClinoStar 给三甲医院时, 可附带本框架作为增值**). Tracks as `/commitments.md` `guo-2026-organoid-irb-checklist-rollout` (Owner: me; fold IRB application checklist into CelVivo industrial-customers program + Robin customer-training core material; commit `templates/类器官IRB申请清单.md` and add a synthesis page at `/sources/literature-guo-2026-front-cell-dev-biol-organoid-ethics-deepread.md`).
 ## Sales training cluster (working-tree additions)
 Per `/sources/git-repo.md` §"Notable entities", `06-Sales/Content/Training-Materials/` contains the following working-tree additions not yet on `main`:
@@ -268,39 +230,30 @@ Per `/sources/git-repo.md` §"Notable entities", `06-Sales/Content/Training-Mate
 The version progression is `基础 → 5大管线 → 深度版 → 终稿修正 → 销量仅看` — the cluster is iterated in place, not committed. See [`/sources/vault-mtime-snapshot-2026-07-16.md`](/sources/vault-mtime-snapshot-2026-07-16.md) for the latest mtime census (CelVivo_销售培训_PPT_v9 = 2026-06-26 14:13).
-## China distributor map (259 dealers across 7 regions — 2026-08-07 baseline)
+## China distributor map (261 dealers across 7 regions)
-From [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md) (Hermes整理, 2026-08-07; **replaces 2026-07-24 baseline of 261 dealers**):
+From [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md) (Hermes整理, 2026-08-07):
-| Region | 8-07 count | 7-24 count | Δ | Share | Main city |
+| Region | Count | Share | Main city |
-| --- | ---: | ---: | ---: | ---: | --- |
+| --- | ---: | ---: | --- |
-| 华北 | 72 | 74 | -2 | 27.8% | 北京 (54) |
+| 华北 | 74 | 28.4% | 北京 (54) |
-| 华东 | 68 | 68 | 0 | 26.3% | 上海 (53) |
+| 华东 | 68 | 26.1% | 上海 (53) |
-| 华南 | 62 | 62 | 0 | 23.9% | 广州 (44) |
+| 华南 | 62 | 23.8% | 广州 (44) |
-| 山东 | 25 | 25 | 0 | 9.7% | 济南 (22) |
+| 山东 | 25 | 9.6% | 济南 (22) |
-| 湖北 | 19 | 19 | 0 | 7.3% | 武汉 (12) |
+| 湖北 | 19 | 7.3% | 武汉 (12) |
-| 西北 | 6 | 6 | 0 | 2.3% | 西安 (6) |
+| 西北 | 6 | 2.3% | 西安 (6) |
-| 西南 | 7 | 7 | 0 | 2.7% | 重庆 (3) |
+| 西南 | 7 | 2.7% | 重庆 (3) |
-| **TOTAL** | **259** | **261** | **-2** | 100% | — |
+| **TOTAL** | **261** | 100% | — |
 Brand keyword map (top 20 by 全国 count): BI 19 / Thermo 19 / Bio-Rad 11 / 赛默飞 8 / 安捷伦 7 / 蔡司 6 / Cytiva 6 / 伯乐 6 / 徕卡 6 / 赛多利斯 5 / Eppendorf 5 / Leica 5 / Beckman 4 / Merck 4 / Waters 4 / Azure 3 / Bruker 3 / Oxford Nanopore 3 / Agilent 3 / Sartorius 3.
 **8-07 独有产品-代理映射 (from `_known_associations.md`):**
 | 产品线 | 关联代理 / 中间方 | 关联客户 / 商机 |
 |---|---|---|
 | CelVivo (ClinoStar) | **济南成全生物科技 (曹沛起)** — 华北 + 山东 跨区重复 | 董慧群 (CelVivo 技术同事) — 8-07 hook 4 候选 |
 | FemtoBiomed (CellShot / PROLIVA) | **9X Bio (汇佰生物)** — 中间方 (0 hit in 259 dealer 表) | TriArm Therapeutics (翁靖傑 上海 CGT/CAR-T, 128 万 Phase1 / 8-10 至 8-14 现场 demo) |
 | 3Brain (HD-MEA) | 0 家代理命中 | 11+ end-customer dossiers (需要补 direct agent or sell direct) |
 | Cellink (BIO X) | 0 家代理命中 | (待补) |
 **Data gap (regional filling rate):** 华东 营收 0/68 / 湖北 营收 0/19 / 华南 销售人数 0/62 — needs补 before next field visit. Documented at [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md) §关键数据缺口.
-**4-vendor break-out is partially resolved:** the 2026-08-07 `_known_associations.md` index identifies CelVivo → 济南成全 + FemtoBiomed → 9X Bio; 3Brain / Cellink direct agents are still 0 (open-question `distributors-3brain-cellink-zero-coverage`).
+**4-vendor break-out is deferred:** brand counts by region for CelVivo / 3Brain / Cellink / Femtobiomed are "待详细匹配" — the cross-match between dealer + vendor product line is not yet in the source page.
 ## CRM — active distributor profiles
-From [`/sources/agents.md`](/sources/agents.md) (last sync 2026-07-28; 2026-08-07 `_known_associations.md` partial resolution):
+From [`/sources/agents.md`](/sources/agents.md) (last sync 2026-07-28):
 | 姓名 | 角色 | 代理商品牌 | 主推产品 | 首次记录 | 状态 | Vault 路径 |
 | --- | --- | --- | --- | --- | --- | --- |
@@ -308,9 +261,7 @@ From [`/sources/agents.md`](/sources/agents.md) (last sync 2026-07-28; 2026-08-0
 This is the only profile currently in the agents bucket. Robin was told about 董慧群 via WeChat DM on 2026-07-28; her role is to help push CelVivo products at the technical / demo / selection stage. Most fields are 待补 (agency name, region, phone, WeChat, customers, opportunities) — this is the only active open question in `/open-questions.md` (see `agent-dong-huiqun-celvivo`).
-**2026-08-07 partial resolution (Hermes hook 4):** 4 个经销商管理 Hook 升级 (`02-Clients/Agents/_known_associations.md` commit `4b237a82`) identifies **济南成全生物科技有限公司 (曹沛起)** as the only CelVivo ClinoStar-listed agent in the 259-dealer China map (华北 + 山东 跨区重复登记). Whether 董慧群 is 济南成全的技术同事 or another dealer is still unverified — tracked as commitment `dong-huiqun-ji-nan-chengquan-link` in `/commitments.md`. The same hook 4 file maps FemtoBiomed CellShot → 9X Bio (汇佰生物) → TriArm Therapeutics (翁靖傑 上海 CGT/CAR-T, 128 万 Phase1 / 8-10 至 8-14 现场 demo), and 3Brain / Cellink / FemtoBiomed direct agents → 0 in the 259 baseline (open-question `distributors-3brain-cellink-zero-coverage`).
+**Privacy rule (Robin 7-28):** `/sources/agents.md` and `/sources/distributors-china-2026.md` contain only base identity (name / role / vendor / region); sensitive fields (phone / WeChat / email / end-customer list / opportunity value) live only in the private Obsidian vault.
 **Privacy rule (Robin 7-28):** `/sources/agents.md` and `/sources/distributors-china-2026.md` contain only base identity (name / role / vendor / region); sensitive fields (phone / WeChat / email / end-customer list / opportunity value) live only in the private Obsidian vault. The 2026-08-07 `_known_associations.md` index adds the **product-line → agent → end-customer → opportunity** mapping chain — but does not break the privacy rule because sensitive fields remain in the private vault files.
 ## End-customer dossier set
@@ -326,8 +277,6 @@ A dedicated subfolder under `05-Documents/Products/Celvivo/Industrial-Customers/
 This is a self-contained CelVivo China commercial effort. The latest mtime census (2026-07-16 snapshot) shows `CelVivo_中国工业客户开发研究报告_20260626_v2.md` as the most-recent file (18 KB, 06-26 11:52). Documented at [`/sources/git-repo.md`](/sources/git-repo.md) §Notable entities.
 **2026-08-17 working-tree addition — `celvivo_commercial/1331651_20260630_131201.pdf`** (56 KB, 2026-06-30 quote PDF migrated into a new folder; **untracked**) — companion to the existing `05-Documents/Products/Celvivo/Industrial-Customers/` commercial-docs subtree. The new folder name signals Robin may be consolidating "Celvivo commercial" documents into a separate vault subtree rather than continuing to nest them under `05-Documents/Products/Celvivo/Industrial-Customers/` (which is the prior convention). If the convention holds, future CelVivo commercial PDFs / quotes / pricing tables will land in `celvivo_commercial/` instead of `05-Documents/Products/Celvivo/Industrial-Customers/`; if it doesn't hold, it's a one-off folder for the 6-30 quote. Watchlist trigger: if a second PDF or commercial doc lands in `celvivo_commercial/` by the next git-repo fetch, the convention change is real; if it stays single-entry, it's a one-off.
 ## Work-rhythm snapshot (2026-07-16)
 From [`/sources/vault-mtime-snapshot-2026-07-16.md`](/sources/vault-mtime-snapshot-2026-07-16.md) (last full mtime census):
@@ -380,25 +329,6 @@ These are source-anchored but not vendor-anchored — they live here for traceab
 - **Work-rhythm snapshot connector** — currently a one-shot `find -mtime` shell command (see `/sources/vault-mtime-snapshot-2026-07-16.md` header). Promote to a weekly cron + auto-write to `/sources/vault-mtime-snapshot-weekly.md` so the work-rhythm signal is durable, not single-snapshot.
 - **End-customer dossier cross-agent page** — 11+ dossiers live in private vault; consider adding a redacted `[name, focus, vendor, region, vault-path]` table to `/sources/agents.md` parallel to the distributor profile pattern. Robin decision pending.
 - **CellShot-TriArm demo plan v3** — current demo plans are v1 (2026-07-21) and v2 (2026-07-22, 邮件用 + 老师版 two-commit split). No v3 yet; the v2 plan lives in vault commit history `1787702c` / `62877d1f` / `62d09c5f`. Promote to `/commitments.md` when v3 lands.
 - **MOC pattern extension (2026-08-10 onward)** — Robin created the first MOC
  (`04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md`, commit `6b717aef`,
  95 lines, 沙牛《AI 时代的 Obsidian 公开课》课时 1 pattern); the MOC's
  `related:` list already names the next planned MOC —
  `[[MOC-3Brain-HD-MEA]]` — plus
  `[[02-Clients/Agents/_known_associations]]` and
  `[[02-Active-Deals/CellShot-TriArm-Demo-计划-v2-老师版-2026-07-20]]`.
  Track on the next git-repo fetch whether the MOC pattern extends to
  MOC-3Brain-HD-MEA, MOC-Cellink-BIO-X, MOC-Femtobiomed-CellShot, etc.
  If ≥3 MOCs land, consider adding a `/themes.md` annex row on
  `vault-knowledge-architecture` and a `/sources/` page that maps the
  MOC graph (file → topics → cross-refs → flywheel cron hooks).
 - **Phase A frontmatter batch rollout (2026-08-10 onward)** — Phase A
  standardized 6 deep-read notes with the 6-field frontmatter
  (doi / journal / year / volume / pages / authors / pmid); ~1,196
  deep-read notes remain without the new fields. Track rollout
  cadence — if Robin completes the batch on a fixed cadence (e.g.
  daily/weekly cron), document the cadence here so future agents can
  answer "what is the frontmatter hygiene status of the vault?".
 ## What to read next
@@ -420,9 +350,3 @@ These are source-anchored but not vendor-anchored — they live here for traceab
 | How does the local-LLM fleet host this evidence? | [`/themes/04-local-llm.md`](/themes/04-local-llm.md) |
 | Where does CelVivo + 3Brain output land? | [`/themes/01-organoid-equipment.md`](/themes/01-organoid-equipment.md) |
 | Where does Cellink output land? | [`/themes/02-bioprinting.md`](/themes/02-bioprinting.md) |
 | What does Quintard 2024 say about vascularized organoid chips? | `obsidian-vault/Literature/Deep-Reads/Organoid/quintard_2024_vasorganoid_chip.md` (vault path; deep-read synthesis not yet split out to `/sources/`) |
 | What does Guo 2026 say about organoid IRB ethics? | `obsidian-vault/Literature/Deep-Reads/Organoid/guo_2026_organoid_ethical_review.md` (vault path; deep-read synthesis not yet split out to `/sources/`) |
 | What's the IRB application checklist for organoid research? | `templates/类器官IRB申请清单.md` v1.0 (vault path; untracked) ||th; deep-read synthesis not yet split out to `/sources/`) |
 | What's the IRB application checklist for organoid research? | `templates/类器官IRB申请清单.md` v1.0 (vault path; untracked) ||t path; untracked) || ||) || ||) || ||ethical_review.md` (vault path; deep-read synthesis not yet split out to `/sources/`) |
 | What's the IRB application checklist for organoid research? | `templates/类器官IRB申请清单.md` v1.0 (vault path; untracked) ||th; deep-read synthesis not yet split out to `/sources/`) |
 | What's the IRB application checklist for organoid research? | `templates/类器官IRB申请清单.md` v1.0 (vault path; untracked) ||t path; untracked) || ||) || ||) || ||
@@ -4,4 +4,4 @@
 - [Theme 2 · 3D bioprinting (Cellink / BIONOVA)](02-bioprinting.md) - Synthesis page for Robin's 3D bioprinting theme — Cellink BIO X / BIONOVA X / Lumen X extrusion and DLP printing hardware for tissue engineering, drug tablets, and scaffold fabrication.
 - [Theme 3 · AI Agent tools (Hermes / Codex / MiniMax code)](03-ai-agents.md) - Synthesis page for Robin's daily-driver AI agent stack — Hermes Agent on WSL, MiniMax code on the desktop, Codex CLI fallback, OpenWiki as cross-agent memory substrate, and supporting toolchain (RustDesk, Gitea, Wiki.js, RAGFlow).
 - [Theme 4 · Local LLM deployment (Ollama / bge-reranker / RAGFlow)](04-local-llm.md) - Synthesis page for Robin's local-LLM fleet — Ollama serve + qwen2.5vl:7b vision model + BAAI/bge-m3 embeddings (Ollama + LM Studio) + bge-reranker rerank + RAGFlow KB retrieval + adjacent NAS subsystems (NocoDB / SeaFile / Wiki.js / Feishu mail).
- [Theme 5 · Robin's personal research (vendor deep reads + sales ammunition + CRM)](05-robin-research.md) - Synthesis page for Robin's personal research portfolio — Obsidian vault + literature deep-read pipeline + sales ammunition + China distributor map + active CRM profiles + work-rhythm snapshots. Output routes into vendor themes 01 (organoid-equipment) and 02 (bioprinting). The 2026-08-23/24 fetch surfaced the largest single-day LDR burst since 2026-07-29 — 5 papers committed to main + new `deepread_40240593/` pipeline workspace directory. The 2026-08-26 + 2026-08-27 + 2026-08-28 + 2026-08-29 + 2026-08-30 fetches observed vault HEAD unchanged at `9d4767c7` (vault silent for the 1st + 2nd + 3rd + 4th + 5th consecutive fetches since the 2026-08-24/25 SECOND 5-paper LDR burst, 5 calendar days stale). The 2026-08-31 fetch observed vault HEAD bumped `9d4767c7` → `391e4713` — **THIRD consecutive single-day 5-paper LDR burst** (Stewart + Aiello + Nguyen + Miao + Yan, all CelVivo-anchored, all in the NEW `obsidian-vault/04-Literature/Deep-Reads/CelVivo/` capital-V subfolder — Robin's first parallel-naming deep-read subfolder convention), ending the 5-day vault silence; combined with the 2026-08-23/24 + 2026-08-24/25 clusters, **15 LDR files in 8 calendar days = the largest sustained 8-day research output** in Robin's vault activity log. The 2026-09-01 + 2026-09-02 + 2026-09-03 + 2026-09-04 + 2026-09-05 + 2026-09-06 + 2026-09-07 + 2026-09-08 + 2026-09-09 fetches observed vault HEAD unchanged at `391e4713` (vault silent for the 1st + 2nd + 3rd + 4th + 5th + 6th + 7th + 8th + 9th consecutive fetches since the 2026-08-31 THIRD consecutive 5-paper CelVivo LDR burst, **9 calendar days stale**). The 2026-09-11 fetch observed vault HEAD bumped `391e4713` → **`09bec367`** — **vault silence streak BROKEN after 11 calendar days** with **2 new vault commits**: `1fd63019` 2026-09-10 (Tomas 2026 HGSC carboplatin/PARPi spheroid+organoid, Western University, **0 vendor callouts**) + `09bec367` 2026-09-11 (Vijakumaran 2026 brain-organoid air-liquid interface oxygen engineering, **first v4 Flywheel auto-sink pipeline entry**); the pipeline has resumed after the 11-day pause. The 4 carry-forward untracked directories (Review + templates + celvivo_commercial + deepread_40240593) bump their carry-forward counts to **30/25/25/18 days** at the 2026-09-11T18:14Z fetch — the `Review/` + `templates/` + `celvivo_commercial/` entries remain **confirmed one-off** (carrying forward unchanged since the 2026-08-28 fetch) and continue as stale / not recurring carry-forward notes; the `deepread_40240593/` working-folder pipeline hypothesis continues to weaken (mtime unchanged across 17 consecutive silent fetches since the 2026-08-24/25 burst). The **2026-09-13T18:08Z fetch** is the **31st git-repo-1 fetch of the 2026-08-07 streak** + the **2nd consecutive vault-silent fetch** after the Tomas 2026 + Vijakumaran 2026 resumption (vault HEAD unchanged at `09bec367`); **1 working-tree modification** was observed at `04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md` (mtime 2026-09-13 11:55:42 +0800) — Robin actively editing the MOC index file but NOT yet committed; the 4 carry-forward untracked directories bump to **32/27/27/20 days** at the 2026-09-13T18:08Z fetch (the highest carry-forward durations of the 2026-08-07 streak); 4 new automated wiki commits in the 48-hour window (`7cfb801` sources-sync 2026-09-12 twenty-ninth + `999a37d` daily update 2026-09-12 + `0447186` daily update 2026-09-13 + `5f33bd3` sources-sync 2026-09-13 thirtieth) bumped wiki HEAD `55d930f` → `5f33bd3`; the 8-dirty-file baseline (down from the prior 10-dirty-file baseline) shows the daily-update cycle cleared `index.md` + `quickstart.md` + `sources/git-repo.md` + `themes.md` while `sources/openwiki-version-drift.md` was newly re-touched; synthesis-layer impact is **none** because vault produced no new external evidence. The **2026-09-16T18:18Z fetch** is the **32nd git-repo-1 fetch of the 2026-08-07 streak** + the **5th consecutive vault-silent fetch** after the Tomas 2026 + Vijakumaran 2026 resumption (vault HEAD unchanged at `09bec367`, **5 calendar days of vault silence**); the **1 working-tree modification** at `04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md` (mtime 2026-09-13 11:55:42 +0800) **persists uncommitted for 3 calendar days** at the 2026-09-16T18:18Z fetch without further changes; the 4 carry-forward untracked directories bump to **35/30/30/23 days** at the 2026-09-16T18:18Z fetch (the highest carry-forward durations of the 2026-08-07 streak); 6 new automated wiki commits in the 72-hour window (`667730f` daily update 2026-09-14 + `09f47d6` sources-sync 2026-09-14 thirty-first + `f38cebf` daily update 2026-09-15 + `f5465f9` sources-sync 2026-09-15 thirty-second + `73dae5e` daily update 2026-09-16 + `ac46732` sources-sync 2026-09-16 thirty-third) bumped wiki HEAD `5f33bd3` → `ac46732`; the 11-dirty-file baseline (upLine truncated
+- [Theme 5 · Robin's personal research (vendor deep reads + sales ammunition + CRM)](05-robin-research.md) - Synthesis page for Robin's personal research portfolio — Obsidian vault + literature deep-read pipeline + sales ammunition + China distributor map + active CRM profiles + work-rhythm snapshots. Output routes into vendor themes 01 (organoid-equipment) and 02 (bioprinting).
@@ -1 +0,0 @@
 # Files
@@ -1,32 +0,0 @@
 #!/usr/bin/env python3
 """Replace Prior Fetches section in /quickstart.md to add 47th pull entry."""
 import re
 with open('/quickstart.md', 'r') as f:
    content = f.read()
 # Use a marker approach: find the exact position where the prior section starts
 # and insert the new entry right before the 2026-09-26 entry.
 # Find the position of the line "## Prior Fetches (selected)"
 section_start = content.find('## Prior Fetches (selected)')
 # Find the first '- **2026-09-26T18:00Z' entry after the section header
 first_entry_pos = content.find('- **2026-09-26T18:00Z (hackernews-1)**', section_start)
 # The insertion point is right at the position of the first list entry
 # (replace the dash to preserve continuity)
 # Construct new entry text
 new_entry = "- **2026-09-27T18:00Z (hackernews-1)** \u2014 forty-seventh pull; `substring-noise-only Algolia lane on 2 of 6 + clean zero on 4 of 6` pull shape \u2014 same as the 2026-09-26 + 2026-09-25 + 2026-09-24 + 2026-09-23 + 2026-09-22 + 2026-09-21 + 2026-09-19 + 2026-09-15 substring-noise-on-2-or-3-of-6 + clean-zero-on-3-or-4-of-6 prior pulls; 15th consecutive clean-zero `CelVivo` pull (**longest zero streak of the 2026-08-07 streak \u2014 second-longest fully-zero substring lane of the streak after `openwiki`**); 11th consecutive fully-zero `openwiki` pull; 13th fully-zero `deepagents` lane (28 of 29 pulls since 2026-08-27 fully-zero on `deepagents`); 2nd clean-zero `3Brain` pull of the 2026-09 streak; Algolia substring-noise: `organoid` (4 false positives) + `Cellink` (4 false positives). **No cluster entry promotion**; `49863864` Unsealed Briefs in Authors' Case v. Microsoft/OpenAI 567 pts + 527 cmts as the **highest-engagement item of the 2026-09-27 pull** + would-be 28th AI-vendor-business-stack cluster entry candidate (Authors' Guild v. OpenAI legal-proceeding rather than a vendor release; adjacent-not-promoted per scope); `49866006` DeepSeek-Elastic-Compute preprint 425 pts + 100 cmts as would-be 29th AI-vendor-business-stack cluster entry candidate (DeepSeek closed-weight model + elastic-compute interpretation; adjacent-not-promoted per scope because DeepSeek is closed-weight and not on Robin's named daily-driver stack); `49865050` Meta-Blocks-President-Lula 254 pts + 524 cmts as would-be 30th AI-vendor-business-stack cluster entry candidate (Meta policy story rather than vendor release; adjacent-not-promoted per scope); `49864336` Installing-NeoVim-caused-original-Vim-undo-files-to-be-deleted 162 pts + 134 cmts as would-be 28th open-weight-LLM cluster entry candidate (NeoVim installation issue, off-scope per scope); `49864969` Tells-of-a-Slop-UI 152 pts + 72 cmts as would-be 29th open-weight-LLM cluster entry candidate (slop-UI critique; adjacent-not-promoted per scope); `49864250` Show HN: Cortex v0.5.0 85 pts + 26 cmts as 11th named-stack-adjacent self-hosted-agentic-substrate cross-walk candidate; `49867319` Show HN: Claude Code adds skills for whiteboarding 61 pts + 38 cmts as named-stack-adjacent Claude-Code-skill cross-walk to the `hermes-agent-v0-19-quicksilver` row; `49863360` Run LLMs locally 38 pts + 9 cmts as would-be 30th open-weight-LLM cluster entry candidate (local-LLM runbook; adjacent-not-promoted per scope because the entry is a runbook rather than a release); `49867655` Show HN: Hermes Agent \u2013 Self-Evolving AI for Real-World Tasks 18 pts + 18 cmts as named-stack-adjacent Hermes-Agent cross-walk to the `hermes-agent-v0-19-quicksilver` row; `49863923` Show HN: Minimax-Direct 12 pts + 9 cmts as 4th MiniMax-M3-cluster-adjacent entry on Hacker News (MiniMax closed-weight model + Direct API tier; adjacent-not-promoted per scope because MiniMax-M3 itself remains canonicalized at the last-seen 2026-08-03 baseline). Last seen on the MiniMax-m3 row stays at 2026-08-03 because the 2026-09-27 pull does not surface any MiniMax-M3 release.\n\n"
 # Insert: prepend the new entry to the existing 2026-09-26 entry
 new_content = content[:first_entry_pos] + new_entry + content[first_entry_pos:]
 with open('/quickstart.md', 'w') as f:
    f.write(new_content)
 print(f"Old length: {len(content)}")
 print(f"New length: {len(new_content)}")
 print(f"Diff: +{len(new_content) - len(content)} chars")