--- type: "Reference" title: "Git repo — evidence index (Obsidian vault, Robin)" description: "Compact manifest of Robin's Obsidian vault + the local OpenWiki wiki, ingested through the local git-repo connector. Two configured repos: obsidian-vault at /home/ldw/workspace (main branch, HEAD a4fa5a32, 2026-08-16, **0 new vault commits in the 2026-08-20T18:09Z → 2026-08-21T18:09Z 24-hour window — vault is silent for the 5th consecutive fetch after the 2026-08-16 Quintard + Guo cluster, 5 calendar days stale**) and openwiki-wiki at /home/ldw/.openwiki/wiki (main branch, HEAD f6c2576, 2026-08-21, **2 new automated wiki commits in the 2026-08-20T18:09Z → 2026-08-21T18:09Z window: `b6dc337` daily update 2026-08-21 + `f6c2576` sources-sync 2026-08-21 — the seventh consecutive sources-sync re-applying the 2026-08-15 count-data wipe pattern**). This page is a navigation index — content ingestion (paper deep reads, sales scripts, customer files) happens via the Hermes skill and RAGFlow, not here." resource: "~/.openwiki/connectors/git-repo/config.json" tags: [git-repo, evidence, vault, openwiki-wiki, source, 2026-08-21, 2026-08-20, 2026-08-19, 2026-08-18, 2026-08-17, 2026-08-15, 2026-08-13] timestamp: 2026-08-21T18:09:00Z --- # Git repo — evidence index (Obsidian vault + OpenWiki wiki) Compact manifest of the two local git repos configured under the `git-repo` connector: Robin's Obsidian vault and the local OpenWiki wiki. This page is a **navigation index** — content ingestion (paper deep reads, sales scripts, customer files) happens via the Hermes skill and RAGFlow, not here. Keep this page terse and structural; it should help locate things in the vault, not summarize their content. ## Connector - **Source instance:** `git-repo-1` (configured under `~/.openwiki/connectors/git-repo/config.json`) - **Configured repos:** - `obsidian-vault` → `/home/ldw/workspace` (Robin Obsidian vault, on `main`, HEAD `a4fa5a323d6dcabeb9eccad49e636ee6ba5f87a6` as of 2026-08-16 +0800 — 7 new vault commits in the 2026-08-15T18:07Z → 2026-08-17T18:09Z 48-hour window: the 2026-08-16 **Quintard 2024 Nat Commun 4-commit LDR cycle** (`0fc8db24` adds file 189 lines → `290e9635` -v2 修图床/双 H1/落款 → `24c713de` -v3 Wiki.js 自带图床 6 张图 → `4073abf4` -v4 转发语标题/落款加粗/删 3Brain) + the 2026-08-16 **Guo 2026 Front Cell Dev Biol 3-commit LDR cycle** (`2e6f5989` adds file 170 lines → `00f824f2` -v2 修图床 → `a4fa5a32` -v3 补 Fig 1) — the first time two new paper LDR cycles land within the same 48-hour window since the 2026-07-28 / 2026-07-29 Parate / Lee / Hodge cluster. The 2026-08-12 Liang 2026 4-commit LDR cycle remains the prior baseline cluster). - `openwiki-wiki` → `/home/ldw/.openwiki/wiki` (the OpenWiki knowledge base itself, on `main`, HEAD `dcb53a2873d37b6396de682d658433c2ea85b376` as of 2026-08-19T +0800 — 8 new wiki-side commits across the 2026-08-15T18:07Z → 2026-08-19T18:08Z window: `151d22b` daily update 2026-08-16 + `997b648` sources-sync 2026-08-16 + `5c70881` daily update 2026-08-17 + `be49285` sources-sync 2026-08-17 + `8127797` daily update 2026-08-18 + `1fc73ae` sources-sync 2026-08-18 + `7e904ec` daily update 2026-08-19 + `dcb53a2` sources-sync 2026-08-19; the `5c70881` daily update also created the new `sources/openwiki-version-drift.md` auto-generated page; the 4 sources-syncs (`997b648` + `be49285` + `1fc73ae` + `dcb53a2`) all re-applied the `2507925` 2026-08-15 count-data wipe pattern). - **Auth:** local paths only — no remote, no credentials. - **Latest fetch:** `2026-08-21T18:09:00Z` (raw manifest `~/.openwiki/connectors/git-repo/raw/2026-08-21T18-08-59-795Z/manifest.json`). - **Source config:** `~/.openwiki/connectors/git-repo/config.json` - **State:** `~/.openwiki/connectors/git-repo/state.json` records `latestIds` per repo; the 2026-08-21T18:09Z fetch observed vault HEAD unchanged at `a4fa5a32` (2026-08-16 — same as the 2026-08-17T18:09Z + 2026-08-18T18:10Z + 2026-08-19T18:08Z + 2026-08-20T18:09Z + 2026-08-21T18:09Z fetches; **0 new vault commits in the 24-hour window — vault is silent for the 5th consecutive fetch** after the 2026-08-16 Quintard + Guo cluster, **5 calendar days stale**), and observed `openwiki-wiki` bumped from `bd30339` (2026-08-20T18:09Z fetch) to `f6c2576` (2 new automated wiki commits in the 24-hour window: `b6dc337` daily update 2026-08-21 + `f6c2576` sources-sync 2026-08-21 — the **seventh** consecutive sources-sync re-applying the 2026-08-15 count-data wipe pattern after `997b648` 2026-08-16 + `be49285` 2026-08-17 + `1fc73ae` 2026-08-18 + `dcb53a2` 2026-08-19 + `bd30339` 2026-08-20 + now `f6c2576` 2026-08-21). ## obsidian-vault — working-tree status (2026-08-21) - **Branch:** `main` - **HEAD:** `a4fa5a323d6dcabeb9eccad49e636ee6ba5f87a6` (vault HEAD **unchanged** at `a4fa5a32` across the 2026-08-21T18:09Z fetch — **0 new commits** in the 2026-08-20T18:09Z → 2026-08-21T18:09Z 24-hour window; the vault is silent for the **5th consecutive fetch** after the 2026-08-17T18:09Z + 2026-08-18T18:10Z + 2026-08-19T18:08Z + 2026-08-20T18:09Z silent windows. The 2026-08-16 Quintard 2024 Nat Commun 4-commit LDR cycle + Guo 2026 Front Cell Dev Biol 3-commit LDR cycle remain the most recent committed vault activity (vault HEAD last bumped on 2026-08-16, **5 calendar days before this fetch** — same state as the 2026-08-17T18:09Z + 2026-08-18T18:10Z + 2026-08-19T18:08Z + 2026-08-20T18:09Z fetches). - **mtime activity in window:** **0 new mtime changes** in the 2026-08-20T18:09Z → 2026-08-21T18:09Z 24-hour window. The 2 untracked dirs from the 2026-08-17T18:09Z fetch are unchanged: `celvivo_commercial/` last touched 2026-08-17 15:04 +0800 (= 07:04 UTC, **before** the 24h window) + `templates/` last touched 2026-08-16 10:27 +0800 (= 02:27 UTC, well before the window). The `Review/zhou2023_computer_vision_microfluidics.md` first-entry file is unchanged from the 2026-08-17T18:09Z fetch (mtime 2026-08-11, **10-day carry-forward** in the untracked set at this fetch — was 9-day at the 2026-08-20T18:09Z fetch; the structural signal continues to weaken per the Notable-entity entry on the `Review/` subfolder). - **Ahead of origin/main:** 20 commits new since 2026-08-03 fetch (unchanged from the 2026-08-17T18:09Z + 2026-08-18T18:10Z + 2026-08-19T18:08Z + 2026-08-20T18:09Z fetches — vault is silent in the 2026-08-20T18:09Z → 2026-08-21T18:09Z window). - **Dirty:** yes — the untracked file set is **unchanged** from the 2026-08-17T18:09Z fetch (no new untracked files or directories appeared in the 2026-08-17T18:09Z → 2026-08-18T18:10Z 24-hour window, no new untracked files or directories appeared in the 2026-08-18T18:10Z → 2026-08-19T18:08Z 24-hour window, no new untracked files or directories appeared in the 2026-08-19T18:08Z → 2026-08-20T18:09Z 24-hour window, and no new untracked files or directories appeared in the 2026-08-20T18:09Z → 2026-08-21T18:09Z 24-hour window either). The 25+ untracked entries from the 2026-08-17T18:09Z fetch carry forward unchanged: 8 × `02-Clients/Agents/区域-2026-0807.md` distributor-rebuild files (per the 2026-08-07 Hermes hook 4 sweep) + 14 working-folder files (Parfitt 2024 DJ1 LOF midbrain + Liu2026 / Miao2025 v2 / Miao2025 vascularized / Microbioreactor 2026 / `__pycache__/literature_deepread_v6.cpython-312.pyc` / `dify精读进度-20260805.md` / `literature_deepread_v6.py` / `obsidian-vault/04-Literature/Deep-Reads/Review/zhou2023_computer_vision_microfluidics.md` / `obsidian-vault/rustdesk-selfhosted-2026-08-05.md` / `retinal_organoid_deep_read_2026-08-07.md` / `文悦精读流水线.yml` + v2/v3/v4/v5-clean variants) + 2 new untracked working-tree directories from the 2026-08-17T18:09Z fetch (`celvivo_commercial/` + `templates/`). The **`Review/zhou2023_computer_vision_microfluidics.md` first entry in the new `Review/` subfolder** is still **untracked** (Robin has not yet committed it) — **10-day carry-forward** at this fetch (was 9-day at the 2026-08-20T18:09Z fetch); the structural signal continues to weaken per the Notable-entity entry on the `Review/` subfolder (the subfolder has been a single-entry watchlist since 2026-08-13, now **8 fetches silent**). - **Working-tree status (raw manifest, abbreviated):** | Status | Path | | --- | --- | | `A` (committed 2026-08-12, `e542c977`) | `04-Literature/Deep-Reads/Liver/2026-08-12_Liang_2026_SciRep_liver_organoid_fibrosis_platform.md` — **NEW external evidence** (Liang Y et al. Sci Rep 2026 DOI 10.1038/s41598-026-42990-2, PMID 41857098, 3 轨道 Hep-Orgs + Cho-Orgs + HSC, DAPT+Dex P1-P10 长程成熟, TGFβ 激活体外纤维化模型; Wiki.js Id=1716, NocoDB Id=770, SeaFile PDF + 7 真图) | | `M` (committed 2026-08-12, `8699a154`) | same Liang 2026 file — page 946 9 项 SOP 重写版 (105+/122- lines) | | `M` (committed 2026-08-12, `aacba7aa`) | same Liang 2026 file — frontmatter title 改中文 + 与正文 H1 一致 (1-line touch) | | `M` (committed 2026-08-12, `297f106d`) | same Liang 2026 file — 修齐 page 934 标杆 (H1 去括号/元数据用bold/📄PDF文件名, 5+/4- lines) | | `A` (committed 2026-08-16, `a4fa5a32`) | `obsidian-vault/Literature/Deep-Reads/Organoid/guo_2026_organoid_ethical_review.md` — **NEW external evidence** (Guo Z, Zhang N 2026 Front Cell Dev Biol DOI 10.3389/fcell.2026.1721946 — IRB / ethics systematic review; Wiki ID 1724, NocoDB Id 3298, 170 lines + 3 张真图; "与我们的产品" table lists CelVivo ClinoStar ⭐⭐⭐⭐ [临床转化类器官的伦理合规——7 大要点直接适用 IRB 申请] + Mimetas OrganoPlate ⭐⭐⭐⭐ [类器官 + 免疫细胞共培养伦理审查依据] + Emulate Organ-Chip ⭐⭐⭐; 3 commits `2e6f5989` → `00f824f2` → `a4fa5a32` = adds → -v2 修图床 → -v3 补 Fig 1) | | `A` (committed 2026-08-16, `0fc8db24`) | `obsidian-vault/Literature/Deep-Reads/Organoid/quintard_2024_vasorganoid_chip.md` — **NEW external evidence** (Quintard C et al. 2024 Nat Commun DOI 10.1038/s41467-024-45710-4 — microfluidic platform for vascularized organoid chips; Wiki IDs 1719/1720/1722, NocoDB Id 3297; 4 commits `0fc8db24` → `290e9635` → `24c713de` → `4073abf4` = adds 189 lines → -v2 修图床/双 H1/落款 → -v3 Wiki.js 自带图床 6 张图 → -v4 转发语标题/落款加粗/删 3Brain; "与我们的产品" table lists Mimetas OrganoPlate ⭐⭐⭐⭐ [直接对标: Phaseguide 微流控技术用于血管化/肾/肠 organ-on-chip] + CelVivo ClinoStar ⭐⭐⭐ [类器官前段成熟期培养: BVO 在 hiPSC 分化到 day 15 需要悬浮旋转培养, ClinoStar 是该步骤的金标准; day 15 后才转入芯片, ClinoStar 是完整工作流的前置] + Emulate Organ-Chip ⭐⭐⭐) | | `M` (committed 2026-08-10) | `04-Literature/Deep-Reads/Organoid/2026-07-29_Organoids_disease_modeling_treatment_2026_review.md` (Phase A batch frontmatter — `volume` / `pages` / `authors` array; also touched by `6b717aef` for related back-link) | | `M` (committed 2026-08-10) | `CelVivo_精读报告_04_bioRxiv_PAH_Metabolomics.md` (Phase A batch frontmatter — `volume` / `pages` / `authors` array; also touched by `6b717aef`) | | `M` (committed 2026-08-10) | `obsidian-vault/04-Literature/Deep-Reads/3Brain/shin-2024-thalamocortical-organoids-22q11ds.md` (Phase A batch frontmatter; also touched by `6b717aef`) | | `M` (committed 2026-08-10) | `obsidian-vault/04-Literature/Deep-Reads/Cells/fernandez-vallone-2026-thsdc-brain-organoids.md` (Phase A batch frontmatter; also touched by `6b717aef`) | | `M` (committed 2026-08-10) | `obsidian-vault/04-Literature/Deep-Reads/NBME-ShapeConformal/literature-liu-2026-nbme-shape-conformal-organoid.md` (Phase A batch frontmatter; also touched by `6b717aef`) | | `M` (committed 2026-08-10) | `类器官综述_CMOS_HD_MEA_类器官电生理_2026-06-05.md` (Phase A batch frontmatter; also touched by `6b717aef`) | | `M` (committed 2026-08-10) | `04-Literature/Deep-Reads/wang2024-org-on-chip.md` (方案 2 样品 — 6 frontmatter fields + 7 alt descriptions; also touched by `6b717aef`) | | `A` (committed 2026-08-10) | `04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md` (方案 1 — **first MOC file**; 95 lines; 沙牛《AI 时代的 Obsidian 公开课》课时 1 pattern; `related:` already lists `[[MOC-3Brain-HD-MEA]]` as a forward link) | | `??` (untracked) | `02-Clients/Agents/全国经销商地图-2026-0807.md` + 7 区域 `*2026-0807.md` files (8-07 distributor baseline refresh — see below) | | `??` (untracked, **NEW 2026-08-17**) | `celvivo_commercial/1331651_20260630_131201.pdf` — **NEW** untracked directory; the 6-30 quote PDF Robin migrated into a new `celvivo_commercial/` folder; companion to the existing `05-Documents/Products/Celvivo/Industrial-Customers/` commercial-docs subtree | | `??` (untracked, **NEW 2026-08-17**) | `templates/类器官IRB申请清单.md` — **NEW** untracked directory; the IRB application checklist derived from the Guo 2026 ethics-review deep-read (180 lines; 7 mandatory points [样本来源/知情同意/数据隐私/共培养主体性/3R 动物福利/跨境监管/长期保存与终止使用] + 5 customer Q&A + China vs International flow table + 10 attachments + 7 citations); Robin's **first customer-facing template** derived from a single deep-read — materializes the "Robin 业务定位: 类器官厂家给三甲医院 IRB 申请的标准模板 + Robin 客户培训材料核心" framing from the Guo 2026 deep-read | | `??` (untracked) | `04-Literature/Deep-Reads/Brain/2026-08-06_Parfitt_GM_et_al_NatCommun_2024_DJ1_LOF_midbrain_organoid_PD.md` | | `??` (untracked) | `Liu2026_NBME_shape_conformal_organoid.md` | | `??` (untracked) | `Miao2025_Cell_v2.md` | | `??` (untracked) | `Miao2025_Cell_vascularized_organoid.md` | | `??` (untracked) | `Microbioreactor_2026_Rosero_FrontBioeng.md` | | `??` (untracked) | `__pycache__/literature_deepread_v6.cpython-312.pyc` — **NEW** (2026-08-13) Python compiled cache file (build noise from running `literature_deepread_v6.py`, ignored) | | `??` (untracked) | `dify精读进度-20260805.md` | | `??` (untracked) | `literature_deepread_v6.py` | | `??` (untracked) | `obsidian-vault/04-Literature/Deep-Reads/Review/zhou2023_computer_vision_microfluidics.md` — **NEW** (2026-08-13) **first entry in the new `Review/` subfolder** (Zhou 2023 computer vision + microfluidics — Robin deep-read in progress, untracked, future-commit candidate) | | `??` (untracked) | `obsidian-vault/rustdesk-selfhosted-2026-08-05.md` | | `??` (untracked) | `retinal_organoid_deep_read_2026-08-07.md` | | `??` (untracked) | `文悦精读流水线.yml` + v2/v3/v4/v5-clean variants | The 8 untracked `*2026-0807.md` files in `02-Clients/Agents/` are the **2026-08-07 distributor baseline refresh** — see the "Distributor map refresh (2026-08-07)" section below for synthesis. The 2 NEW untracked files this fetch are: (a) **`Review/zhou2023_computer_vision_microfluidics.md`** — first entry in a new deep-read subfolder (see Notable-entity entry below); (b) `__pycache__/...pyc` — build noise, ignored. ### Recent commits (latest first) | Date | Hash | Note | | --- | --- | --- | | 2026-08-16 | `a4fa5a32` | **literature: review 类 Guo 2026 -v3 补 Fig 1** — in-place update ID 1724, 3 张图全 | | 2026-08-16 | `00f824f2` | **literature: review 类 Guo 2026 -v2 修图床** — in-place update ID 1724, 加 2 张 Wiki.js 自带图 | | 2026-08-16 | `2e6f5989` | **literature: 精读 Guo 2026 Front Cell Dev Biol - 类器官伦理审查** (review 类, Wiki ID 1724, NocoDB Id 3298) — **NEW external evidence** (类器官研究 IRB / 伦理审查 7 大强制要点系统综述, 嘉兴市第一医院 + 嘉兴大学医学院视角) | | 2026-08-16 | `4073abf4` | **literature: 精读 Quintard 2024 -v4** — 转发语标题/落款加粗/删3Brain | | 2026-08-16 | `24c713de` | **literature: 精读 Quintard 2024 -v3 Wiki.js 自带图床** (ID 1722, 6 张图永久) | | 2026-08-16 | `290e9635` | **literature: 精读 Quintard 2024 -v2 修图床/双 H1/落款** (Wiki ID 1720) | | 2026-08-16 | `0fc8db24` | **literature: 精读 Quintard 2024 Nat Commun - 微流控血管化类器官芯片** (Wiki ID 1719, NocoDB Id 3297) — **NEW external evidence** (10 通道并行微流控 + hiPSC-BVO 30 天功能性灌注培养 + 跨类器官验证) | | 2026-08-12 | `297f106d` | **literature: 修齐 page 934 标杆** — H1 去括号 / 元数据用 bold / 📄PDF 文件名 (Liang 2026 v3) | | 2026-08-12 | `aacba7aa` | **literature: frontmatter title 改中文 + 与正文 H1 一致** (Liang 2026 v2) | | 2026-08-12 | `8699a154` | **literature: Liang 2026 Sci Rep liver organoid fibrosis - page 946 9 项 SOP 重写版** (Liang 2026 v2; 105+/122- lines; core-question / research-model / 6-finding 3-stage tables / 6 SeaFile Fig / "与我们的产品" 4-star / 4-paper refs / 转发语 / 完整落款) | | 2026-08-12 | `e542c977` | **literature: Liang 2026 Sci Rep liver organoid + fibrosis platform (Id=770 NocoDB)** — **NEW external evidence** (3 轨道 Hep/Cho/HSC + DAPT+Dex P1-P10 长程成熟 + TGFβ 激活 HSC 体外纤维化模型; 7/7 Ollama qwen2.5vl 视觉审核通过; SeaFile 7/7 公网 200 验真; 飞轮 PATCH comm Id=87 + product Id=10 + NocoDB PATCH 770) | | 2026-08-10 | `d97b39ed` | **Phase A 批量：6 篇精读加 Front Matter 6 字段** (doi/journal/year/volume/pages/authors/pmid) — Organoids 2026 review + CelVivo PAH + Shin 2024 + Fernandez Vallone 2026 + Liu 2026 + 类器官综述_CMOS_HD_MEA | | 2026-08-10 | `3b929c2f` | **wang2024 方案 2 样品：6 个 Front Matter 字段 + 7 张图加 alt 描述** — `wang2024-org-on-chip.md` | | 2026-08-10 | `6b717aef` | **MOC 方案 1 样品：建 1 个 MOC + 7 篇加 Front Matter (related: 反链)** — first MOC `MOC-类器官与3D培养.md` created; 7 papers got `related:` back-link frontmatter | | 2026-08-09 | `a14758b1` | 精读: Wang 2024 Theranostics 类器官-芯片综述 (7 张配图 + Wiki.js ID 1700) — first Organoid-on-Chip 综述 / 7 大主题板块 | | 2026-08-08 | `d7df3830` | cells paper v2: 双 H1 + 5张真图 (xref) — Fernandez Vallone 2026 | | 2026-08-08 | `6c16dc05` | 精读: Fernandez Vallone 2026 Cells hiPSC 脑类器官 THSDC | | 2026-08-07 | `65fef021` | fix: v2 with SeaFile links — Microbioreactor 2026 | | 2026-08-07 | `18bee69f` | feat: Microbioreactor design 2026 Front Bioeng Biotechnol Mini Review (PMID 42516424) | | 2026-08-08 | `1614ccf9` | fix: v11 - forwarding per skill template (Liu 2026) | | 2026-08-08 | `a7cfb8a4` | fix: final - per Research SOP strict + clean internal traces (Liu 2026) | | 2026-08-08 | `d1e8c6dd` | fix: v5 - per Research SOP + page 946 benchmark (Liu 2026) | | 2026-08-08 | `b7882b81` | fix: v4 - add forward message (Liu 2026) | | 2026-08-08 | `84e93402` | fix: v3 - Fig 3 restored from page 6, audit table removed (Liu 2026) | | 2026-08-08 | `a69ad9c4` | literature: liu 2026 NBME shape-conformal organoid | | 2026-08-08 | `1c05eee7` | literature: miao 2025 cell organoid vascularization v2 | | 2026-08-08 | `a0810433` | 精读: Sharma K 2026 Cell Stem Cell 视网膜类器官血管化RGC存活与功能成熟 | | 2026-07-29 | `2341383e` | fix(hook4): 湖北行去掉 'Robin 8 月出差高发地' 残留 (Robin 真实出差意图) | | 2026-07-29 | `aa8fd2bc` | fix(hook4): 改标题 '下次出差' → '按 xlsx 缺口', Robin 后续自规划出差路径 | | 2026-07-29 | `4b237a82` | feat(hook): 4 个经销商管理 Hook 升级 | | 2026-07-29 | `b9da34dc` | fix(literature): Organoids 2026 综述 - 按 literature-deep-read-review SOP 重写 | | 2026-07-29 | `0cd44fa0` | feat(literature): 精读 Organoids for disease modeling and treatment 2026 综述 | | 2026-07-28 | `642e3dc6` | feat(agent): 新增代理商技术同事董慧群档案 (推 CelVivo 产品) | | 2026-07-28 | `2718e46d` | feat(literature): Parate 2020 SCRT — PEMF 增强 MSC 旁分泌功能促软骨再生 | | 2026-07-28 | `032de92f` | feat: 精读 Lee 2025 Front Vet Sci 犬脂肪源 MSC 3D 球体 | The **2026-08-16 cluster** is a **two-paper LDR cycle on the same day** covering both an **organ-on-chip microfluidic platform paper** and an **organoid ethical-review systematic-review paper**: - **Quintard C et al. (2024) Nat Commun DOI 10.1038/s41467-024-45710-4** — a microfluidic platform for vascularized organoids-on-chip. The paper establishes: (i) 10-channel parallel microfluidic chip (COC 热压成型, U 型捕获位 300-800 µm 可调); (ii) fibrin + Matrigel hydrogel with Landau-Levich-Bretherton 效应 → 100% 捕获效率 in 10 sec per channel; (iii) hiPSC-derived blood vessel organoids (BVO, day 15) + GFP-HUVEC + 纤维细胞共培养 → 30 天功能性灌注培养; (iv) 壁剪切速率 27-2000 s⁻¹, mean 134-531 s⁻¹ (与人体毛细血管生理范围 50-1900 s⁻¹ 完美匹配); (v) 层级化血管: 37 µm 上游动脉-静脉 + 8 µm BVO 毛细管. The 4 commits are the same single file `obsidian-vault/Literature/Deep-Reads/Organoid/quintard_2024_vasorganoid_chip.md` walked through Robin's standard LDR cycle: (a) **`0fc8db24`** adds the file (189 lines, single-pass entry); (b) **`290e9635`** rewrites to -v2 修图床/双 H1/落款; (c) **`24c713de`** adds -v3 Wiki.js 自带 图床 6 张图 (永久); (d) **`4073abf4`** is the -v4 转发语标题/落款 加粗 + 删 3Brain 工具名硬门槛合规修正. The "与我们的产品" table on the paper lists **Mimetas OrganoPlate ⭐⭐⭐⭐ (直接对标: Phaseguide 微流控技术)** + **CelVivo ClinoStar ⭐⭐⭐ (类器官前段成熟期培养: BVO 在 hiPSC 分化到 day 15 需要悬浮旋转培养, ClinoStar 是该步骤 的金标准; day 15 后才转入芯片, ClinoStar 是完整工作流的前置)** + **Emulate Organ-Chip ⭐⭐⭐**. - **Guo Z, Zhang N (2026) Front Cell Dev Biol DOI 10.3389/fcell.2026.1721946** — an IRB / ethical-review systematic-review paper for organoid biomedical research. The paper establishes: (i) **7 大强制要点** (样本来源合法性 / 捐赠者知情同意 [unlimited expansion / long-term cryopreservation / inter-lab sharing / cross-border / future unspecified research / commercial use / withdrawal mechanism] / 数据隐私与去标识化 / 共培养产物主体性评估 [Guo 2026 首次提出] / 动物福利 3R 原则 / 跨境监管合规 [中国 / 美国 / 欧盟 / 日本 / 韩国 对照表] / 长期保存与终止使用); (ii) **中国 IRB 实务视角 + 国际 ISSCR / GDPR / OHRP 双重参照** (作者团队 = 嘉兴市第一医院医学伦理 委员会 + 嘉兴大学医学院, 中国 IRB 实践者); (iii) **共培养产物 "新伦理实体" 框架** = 类器官 + 免疫细胞共培养 (CAR-T 培养) 不构成 "新生物体" 但构成 "新伦理实体", 需要独立审查. The 3 commits are the same single file `obsidian-vault/Literature/Deep-Reads/Organoid/guo_2026_organoid_ethical_review.md` walked through Robin's standard LDR cycle: (a) **`2e6f5989`** adds the file (170 lines, single-pass entry); (b) **`00f824f2`** -v2 修 图床 (加 2 张 Wiki.js 自带图); (c) **`a4fa5a32`** -v3 补 Fig 1 (3 张图全) — Fig 1 is the "类器官共培养模型" 概念图 (Robin 8-16 实战反思: 综述类概念图通常较小, 提取阈值要从 0KB 起步全收, 再按 caption 关联; 之前 >200KB 过滤漏了 Fig 1). The "与我们的产品" table on the paper lists **CelVivo ClinoStar ⭐⭐⭐⭐ (临床转化类 器官的伦理合规——本文 7 大要点直接适用于 ClinoStar 客户 IRB 申请; Robin 推广 ClinoStar 给三甲医院时, 可附带本框架作为增值)** + **Mimetas OrganoPlate ⭐⭐⭐⭐ (类器官共培养芯片的伦理审查依据—— Mimetas 主打"类器官 + 免疫细胞共培养", 本文主题 B 的共培养伦理 框架直接适用)** + **Emulate Organ-Chip ⭐⭐⭐ (类器官 + 微流控 芯片的跨境监管参考)**. The **2026-08-12 cluster** is a **single-paper LDR cycle** on **Liang Y et al. (2026) Sci Rep DOI 10.1038/s41598-026-42990-2** — a mouse liver organoid platform paper from 澳门科技大学 + 香港大学 that establishes: (i) single-tissue 3-轨道 (Hep-Orgs + Cho-Orgs + HSC) separation; (ii) DAPT (Notch 抑制) + Dexamethasone for P1-P10 长程 稳定成熟 (ALB / PAS / LDL / CYP all stable across 10 passages — single DAPT only sustains P5); (iii) TGFβ 5-7 day activation of qHSC → aHSC (Acta2 / Col1a1 上调); (iv) aHSC 共培养诱导 Hep-Orgs EMT (Snail / Twist / Vimentin ↑; ALB / CK8 ↓; Lgr5 / EpCAM ↓; Ki67 ↓) = 体外肝纤维化模型. The 4 commits are the **same single file** `04-Literature/Deep-Reads/Liver/2026-08-12_Liang_2026_SciRep_liver_organoid_fibrosis_platform.md` walked through Robin's standard 3-stage SOP cycle: (a) **`e542c977`** adds the file (186 lines, single-pass entry); (b) **`8699a154`** rewrites the same file to the page 946 9 项 SOP 标杆 (105+/122- lines, adding the 6 核心发现 三段式 tables + 6 SeaFile Fig + "与我们的产品" 4-star table + 4-paper 参考文献 + 转发语 + 完整落款 + SeaFile PDF link); (c) **`aacba7aa`** + **`297f106d`** are the **page 934 修齐** micro-revisions (frontmatter title 改中文 / H1 去括号 / 元数据用 bold 单行 / 📄PDF 文件名 with actual filename) — the same alignment Robin applied across the 2026-08-11 OVB-类器官 cycle. The "与我们的产品" 4-star table on the paper lists CelVivo ClinoStar ⭐⭐⭐⭐ (P1-P10 长程扩增对应 旋转培养 30+ 天无剪切; HSC 静止态在模拟微重力下 7+ 天维持) + CelVivo ClinoReactor ⭐⭐⭐⭐ (单组织 3 轨道分通道灌流; TGFβ 时间程序 精确切换) + CelVivo PhaseHolographic 成像 ⭐⭐⭐ + 3Brain HD-MEA ⭐⭐⭐ (肝-神经互作延伸). **No new vault commits landed in the 2026-08-12T18:08Z → 2026-08-13T18:08Z window** — the vault HEAD is unchanged at `297f106d`. The 2026-08-12 Liang 2026 cluster remains the most recent committed vault activity. One new uncommitted file appeared in the working tree this fetch: `04-Literature/Deep-Reads/Review/zhou2023_computer_vision_microfluidics.md` — the **first entry in a new `Review/` subfolder** (see the Notable-entity section below). **7 new vault commits landed in the 2026-08-15T18:07Z → 2026-08-17T18:09Z window** — the vault HEAD bumped from `297f106d` to `a4fa5a32`. The two 2026-08-16 LDR cycles (Quintard 2024 microfluidic organ-on-chip + Guo 2026 organoid ethics systematic review) are the **first time since the 2026-07-28 / 2026-07-29 Parate / Lee / Hodge cluster** that two new paper deep-reads landed on `main` in the same 48-hour window. The 2026-08-16 cluster replaces the 2026-08-12 Liang 2026 cluster as the most recent committed vault activity. Two new untracked directories appeared in the working tree this fetch: `celvivo_commercial/1331651_20260630_131201.pdf` (the 6-30 quote PDF migrated into a new folder) + `templates/类器官IRB申请清单.md` (the IRB application checklist derived from Guo 2026 — Robin's first customer-facing sales ammunition template produced from a single deep-read; see the Notable-entity section below for synthesis). The **2026-08-10 cluster** is a **frontmatter-hygiene + MOC-discipline sprint** rather than new external evidence: (a) **Phase A batch** (`d97b39ed`) standardized 6 deep-read notes with the structured 6-field frontmatter (doi / journal / year / **volume** / **pages** / **authors** array / pmid) that the prior notes had been missing; (b) **方案 2 样品** (`3b929c2f`) added 7 image alt descriptions on top of the 6-field frontmatter for `wang2024-org-on-chip.md`; (c) **MOC 方案 1 样品** (`6b717aef`) created Robin's first Map-of-Content file (`04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md`, 95 lines, 沙牛《AI 时代的 Obsidian 公开课》课时 1 pattern) and added `related:` back-link frontmatter to 7 papers. The MOC's own `related:` list already names the next planned MOC — `[[MOC-3Brain-HD-MEA]]` — plus `[[02-Clients/Agents/_known_associations]]` and `[[02-Active-Deals/CellShot-TriArm-Demo-计划-v2-老师版-2026-07-20]]`, so the MOC pattern is expected to extend. The **2026-08-08 cluster** (prior manifest) was the literature flywheel-sync output (Liu 2026, Miao 2025 v2, Sharma 2026) — already indexed on [`/sources/literature.md`](/sources/literature.md). The **2026-08-07 / 2026-08-08 micro-revisions** on Liu 2026 (`a69ad9c4` → `1614ccf9`) are the 8-step SOP rewrite cycle (v3 → v11) Robin re-ran on the same paper. ## openwiki-wiki — working-tree status (2026-08-21) - **Branch:** `main` - **HEAD:** `f6c2576` (the `chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-21)` commit — same auto-source-sync job that carried the 2026-08-15 count-data wipe + re-applied the pattern on 2026-08-16 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + now 2026-08-21; see Notable-entity § "2026-08-15 sources-sync bug" for the operational note). The 2026-08-21T18:09Z fetch observed wiki HEAD bumped from `bd30339` (2026-08-20T18:09Z fetch) to `f6c2576` — **2 new automated wiki commits** in the 2026-08-20T18:09Z → 2026-08-21T18:09Z 24-hour window: (a) `b6dc337` chore: daily update 2026-08-21 (2026-08-21 02:27 +0800); (b) `f6c2576` chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-21, 2026-08-21 02:30 +0800). Both commits are routine auto-orchestration — the `b6dc337` daily update carried the synthesis-layer edits from the prior HN-1 2026-08-21T18:00Z + web-search-1 2026-08-21 (skipped) + git-repo-1 2026-08-20T18:09Z runs; the `f6c2576` sources-sync re-applied the count-data wipe pattern on NocoDB / SeaFile / Wiki.js / RAGFlow for the **seventh** consecutive time (after `997b648` 2026-08-16 + `be49285` 2026-08-17 + `1fc73ae` 2026-08-18 + `dcb53a2` 2026-08-19 + `bd30339` 2026-08-20 + now `f6c2576` 2026-08-21). - **Working-tree state:** 9 modified files (uncommitted — pending next CLI orchestration). The 2026-08-21T18:09Z fetch observed the working tree drop from 10 uncommitted files (per the 2026-08-20T18:09Z fetch) to 9 uncommitted files (per `git status` at the 2026-08-21 fetch) — the `sources/index.md` file that was re-appearing as dirty in the working tree at the 2026-08-20 fetch has now been committed by `b6dc337` 2026-08-21 daily update. The 9 dirty files at this fetch are: - `.last-update.json` — CLI metadata, will be updated when this run's `status: complete` lands. - `quickstart.md` — contains the accumulated "Latest update" paragraphs from the prior HN-1 2026-08-15 + web-search-1 2026-08-15 + git-repo-1 2026-08-13 runs, plus the "Latest update — git-repo-1 (2026-08-15T18:07Z)" + "Latest update — git-repo-1 (2026-08-17T18:09Z)" + "Latest update — git-repo-1 (2026-08-18T18:10Z)" + "Latest update — git-repo-1 (2026-08-19T18:08Z)" + "Latest update — git-repo-1 (2026-08-20T18:09Z)" paragraphs added by the 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 git-repo runs; this git-repo-1 2026-08-21T18:09Z run adds the "Latest update — git-repo-1 (2026-08-21T18:09Z)" paragraph and updates the Backlog git-repo entry to reflect the new wiki HEAD `f6c2576`. - `sources/README.md` — refreshed connector-roll table row for web-search-1 (added the 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 skips to the 9-entry skip streak) + added frontmatter placeholders to nocodb.md / ragflow.md / seafile.md / wikijs.md during the 2026-08-15 daily update. - `sources/hackernews.md` — accumulated "Latest update — 2026-08-15 18:00 UTC" + "Latest update — 2026-08-16 18:00 UTC" + "Latest update — 2026-08-17 18:00 UTC" + "Latest update — 2026-08-18 18:00 UTC" + "Latest update — 2026-08-19 18:00 UTC" + "Latest update — 2026-08-20 18:00 UTC" + "Latest update — 2026-08-21 18:00 UTC" sections from the prior HN-1 runs (Auto-research with codex 232x Faster Kernel + Anthropic multi-agent + Stripe/OpenRouter + Copilot Autofix + Qwen 3.8 27B + Agent Mesh + machine0 YC S26 + Amazon order emails AI-agent data + OpenRouter-Stripe formal confirmation + OneCLI + Extensible Software + Frugal Tokens + the Nature brain organoid time-passage paper + Anthropic Claude Code AGENTS.md feature request + Unsloth Dynamic 3.0 GGUFs + DeepSeek-v4-flash- vision-exp + Show HN Proliferate + self-hosted sandboxed agentic software factory + GitHub August 17 outage post-mortem + LiteLLM hiring flag-for-traceability callouts + the 4th / 5th / 6th / 7th / 8th / 9th / 10th consecutive empty / noise-only Algolia lane streak notes) — landed in uncommitted state during the HN-1 runs. - `sources/nocodb.md` — `openwiki_generated: true` placeholder frontmatter auto-applied during the 2026-08-15 daily update + carried forward in 2026-08-16 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 daily updates; **placeholder resolved by the 2026-08-18T18:10Z update run** (proper `type` / `title` / `description` / `tags` frontmatter now in place); **count data wiped** by `2507925` 2026-08-15 sources-sync (NocoDB went from 6614 → 0 records) and the wipe persists across the 6 subsequent sources-syncs (`997b648` 2026-08-16 + `be49285` 2026-08-17 + `1fc73ae` 2026-08-18 + `dcb53a2` 2026-08-19 + `bd30339` 2026-08-20 + now `f6c2576` 2026-08-21 — the count stays at 0 across all 7 sources-syncs); body content (13 literature tables + record counts from `1737454` baseline) remains intact. - `sources/ragflow.md` — same `openwiki_generated: true` placeholder auto-applied during the 2026-08-15 daily update; **placeholder resolved by the 2026-08-18T18:10Z update run** (proper `type` / `title` / `description` / `tags` frontmatter now in place); **count data wiped** by `2507925` 2026-08-15 sources-sync (landing went from 200 → 000); body content (14 KBs + service-availability table + degraded-path note) remains intact. - `sources/seafile.md` — same `openwiki_generated: true` placeholder auto-applied during the 2026-08-15 daily update; **placeholder resolved by the 2026-08-18T18:10Z update run** (proper `type` / `title` / `description` / `tags` frontmatter now in place); **count data wiped** by `2507925` 2026-08-15 sources-sync (libraries table emptied — SeaFile was already empty in `1737454` already — a separate, older cron issue not introduced by `2507925`); body content (API config + integration chain) remains intact. - `sources/web-search.md` — accumulated "2026-08-15 attempted update — skipped" + "2026-08-17 attempted update — skipped" + "2026-08-18 attempted update — skipped" + "2026-08-19 attempted update — skipped" + "2026-08-20 attempted update — skipped" + "2026-08-21 attempted update — skipped" sections from the web-search-1 2026-08-15 + web-search-1 2026-08-17 + web-search-1 2026-08-18 + web-search-1 2026-08-19 + web-search-1 2026-08-20 + web-search-1 2026-08-21 runs (5th + 6th + 7th + 8th + 9th + 10th consecutive skips on the same code path). - `sources/wikijs.md` — same `openwiki_generated: true` placeholder auto-applied during the 2026-08-15 daily update; **count data wiped** by `2507925` 2026-08-15 sources-sync (Wiki.js went from 83 → 0 unique pages; ID range 22..1704 → 0..0) and the wipe persists across the 6 subsequent sources-syncs (`997b648` 2026-08-16 + `be49285` 2026-08-17 + `1fc73ae` 2026-08-18 + `dcb53a2` 2026-08-19 + `bd30339` 2026-08-20 + now `f6c2576` 2026-08-21). - **Auth:** local path only — no remote, no credentials. - **New file in this window:** `sources/openwiki-version-drift.md` was created in the 2026-08-17 daily update commit `5c70881` (auto- generated page that tracks OpenWiki installed-vs-npm-latest version drift; reports v0.3.1 local → v0.3.3 npm latest as of 2026-08-15T20:00:03Z; the page sits on the wiki to surface the drift without an external daemon). - **Auth:** local path only — no remote, no credentials. ### Recent commits (latest first) | Date | Hash | Note | | --- | --- | --- | | 2026-08-21 | `f6c2576` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-21) — **count-data wipe re-applied** for the **seventh** consecutive sources-sync (after 2026-08-15 `2507925` + 2026-08-16 `997b648` + 2026-08-17 `be49285` + 2026-08-18 `1fc73ae` + 2026-08-19 `dcb53a2` + 2026-08-20 `bd30339`); see Notable-entity § "2026-08-15 sources-sync bug" | | 2026-08-21 | `b6dc337` | chore: daily update 2026-08-21 (synthesis-layer edits accumulated from the prior HN-1 2026-08-21T18:00Z + web-search-1 2026-08-21 (skipped) + git-repo-1 2026-08-20T18:09Z runs; committed `sources/index.md` from the 2026-08-20 dirty set) | | 2026-08-20 | `bd30339` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-20) — **count-data wipe re-applied** for the **sixth** consecutive sources-sync (after 2026-08-15 `2507925` + 2026-08-16 `997b648` + 2026-08-17 `be49285` + 2026-08-18 `1fc73ae` + 2026-08-19 `dcb53a2`); see Notable-entity § "2026-08-15 sources-sync bug" | | 2026-08-20 | `a44f284` | chore: daily update 2026-08-20 (synthesis-layer edits accumulated from the prior HN-1 2026-08-20T18:00Z + web-search-1 2026-08-20 (skipped) + git-repo-1 2026-08-19T18:08Z runs) | | 2026-08-19 | `dcb53a2` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-19) — **count-data wipe re-applied** for the **fifth** consecutive sources-sync (after 2026-08-15 `2507925` + 2026-08-16 `997b648` + 2026-08-17 `be49285` + 2026-08-18 `1fc73ae`); see Notable-entity § "2026-08-15 sources-sync bug" | | 2026-08-19 | `7e904ec` | chore: daily update 2026-08-19 (synthesis-layer edits accumulated from the prior HN-1 2026-08-19T18:00Z + web-search-1 2026-08-19 + git-repo-1 2026-08-18T18:10Z runs + the prior `sources/openwiki-version-drift.md` carryover) | | 2026-08-18 | `1fc73ae` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-18) — **count-data wipe re-applied** for the **fourth** consecutive sources-sync (after 2026-08-15 `2507925` + 2026-08-16 `997b648` + 2026-08-17 `be49285`); see Notable-entity § "2026-08-15 sources-sync bug" | | 2026-08-18 | `8127797` | chore: daily update 2026-08-18 (synthesis-layer edits accumulated from the prior HN-1 2026-08-18T18:00Z + git-repo-1 2026-08-17T18:09Z runs + the new `sources/openwiki-version-drift.md` carryover) | | 2026-08-17 | `be49285` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-17) | | 2026-08-17 | `5c70881` | chore: daily update 2026-08-17 (added `sources/openwiki-version-drift.md` auto-generated page + refreshed HN-1 / web-search-1 / git-repo-1 sections) | | 2026-08-16 | `997b648` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-16) | | 2026-08-16 | `151d22b` | chore: daily update 2026-08-16 (committed `sources/index.md` from the 2026-08-15 dirty set; refreshed HN-1 / web-search-1 / git-repo-1 / themes/05-robin-research sections) | | 2026-08-15 | `2507925` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-15) — **count-data wipe** (NocoDB 6614 → 0, Wiki.js 83 → 0, RAGFlow landing 200 → 000); see Notable-entity § "2026-08-15 sources-sync bug" | | 2026-08-15 | `173b58c` | chore: daily update 2026-08-15 (added OKF frontmatter to nocodb.md / ragflow.md / seafile.md / wikijs.md) | | 2026-08-14 | `6258717` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-14) | | 2026-08-14 | `021e929` | chore: daily update 2026-08-14 | | 2026-08-13 | `1737454` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-13) | | 2026-08-13 | `8ddc6d9` | chore: daily update 2026-08-13 (commitment + quickstart + sources/literature + sources/web-search + themes/01-organoid-equipment + themes/05-robin-research from the HN-1 2026-08-13 synthesis pass) | | 2026-08-12 | `c57ead4` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-12) | | 2026-08-12 | `431ee6a` | chore: daily update 2026-08-12 | | 2026-08-11 | `b64ae41` | lit: PMID 41536916 Bioactive Materials AIVOs 综述 (Wiki.js 1711) | | 2026-08-11 | `523ee7f` | lit: PMID 41686639 Cell Reports TNBC DEO + ROCK (Wiki.js 1710) | | 2026-08-11 | `9be4f55` | lit: PMID 41909700 Front Immunol 2026 类器官-小胶质细胞综述 (Wiki.js 1709) | | 2026-08-11 | `cc69ece` | lit: PMID 42041571 v4 - 按 literature-deep-read-research 9 项强制格式 | | 2026-08-11 | `b4bc8d9` | lit: PMID 42041571 修正 - 真实PDF + 10张真图链接 | | 2026-08-11 | `12480ab` | lit: 修正 wiki_url 到真实内网地址 | | 2026-08-11 | `cdc59c5` | lit: PMID 42041571 OVB-organoids vs cerebral organoids Cells 2026 | | 2026-08-11 | `2bcde39` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-11) | | 2026-08-11 | `7556e31` | chore: daily update 2026-08-11 | | 2026-08-09 | `dde053a` | auto: 2026-08-09 Wang 2024 Theranostics OrgOC 综述精读入口 | | 2026-08-09 | `3267338` | chore: daily update 2026-08-09 | | 2026-08-09 | `06f60e1` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-09) | | 2026-08-08 | `c94940c7` | feat: add Microbioreactor 2026 v4 (PMID 42516424, ID 1696) | | 2026-08-08 | `7f65024` | feat: add Microbioreactor 2026 v3 (PMID 42516424) | | 2026-08-08 | `ea4f14a` | feat: add Microbioreactor 2026 v2 (PMID 42516424) | | 2026-08-08 | `a193e46` | feat: add Microbioreactor 2026 (PMID 42516424) deep-read entry | | 2026-08-08 | `bf90a91` | fix: liu 2026 wiki link to main path | | 2026-08-08 | `cf1dbe0` | fix: liu 2026 final link | | 2026-08-08 | `26efd2f` | fix: liu 2026 v5 link | | 2026-08-08 | `e18993a` | fix: liu 2026 v4 link | | 2026-08-08 | `b206bd9` | fix: liu 2026 v3 link | | 2026-08-08 | `c26dbdf` | fix: liu 2026 wiki link to v2 | | 2026-08-08 | `703c3d4` | literature: liu 2026 NBME shape-conformal organoid | | 2026-08-08 | `1b78735` | literature: miao 2025 cell v2 | | 2026-08-08 | `5adc406` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-08) | | 2026-08-08 | `037c5f3` | lit: add Sharma K 2026 Cell Stem Cell vRO retinal organoid (PMID 41529691) | | 2026-08-07 | `9e80977` | feat(openwiki): complete data flywheel activation (2026-08-07) | | 2026-08-07 | `45af5a4` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-07) | | 2026-08-07 | `bcd4a4f` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-07) | | 2026-08-07 | `0bbef0f` | feat(openwiki v0.3.1 --update): generate themes 4-5 + index.md + themes/ + sources/ index (2026-08-07) | | 2026-08-07 | `285c53b` | feat(openwiki v0.3.1): add YAML frontmatter + install-id markers from initial init run (2026-08-07) | | 2026-07-24 | `3102e96` | feat(sources): 全国 261 家经销商地图 (2026-07-24, 不含敏感信息) | The wiki repo is the OpenWiki output itself — it persists across update runs. **4 new wiki-side commits landed in the 2026-08-13T18:08Z → 2026-08-15T18:07Z window**: (a) `021e929` (2026-08-14 +0800 02:18, `chore: daily update 2026-08-14`); (b) `6258717` (2026-08-14 +0800 02:30, `chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-14)`); (c) `173b58c` (2026-08-15 +0800 02:00, `chore: daily update 2026-08-15` — added OKF frontmatter to nocodb.md / ragflow.md / seafile.md / wikijs.md); (d) `2507925` (2026-08-15 +0800 02:31, `chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-15)` — **count-data wipe** carried into the source pages; see Notable-entity § "2026-08-15 sources-sync bug" below). Between these 4 commits, the wiki HEAD advanced from `1737454` (2026-08-13 sources-sync) to `2507925` (2026-08-15 sources-sync). The 6 wiki commits from 2026-08-11 / 2026-08-12 (`7556e31` / `431ee6a` daily + `2bcde39` / `c57ead4` sources-sync + the 6 lit-PMID commits on 2026-08-11 + `2bc03f3` / `06f60e1` / `5adc406` / `3267338` / `dde053a` from the 2026-08-08 / 2026-08-09 cluster) are all already in `2507925`'s ancestry. The **Liang 2026 wiki sync** has not yet landed (the `/sources/literature.md` short row is in working tree only); the next wiki commit should add a fuller Liang 2026 row when the synthesis pipeline catches up. ### Summary of last 48 hours | Window (UTC) | Vault | Wiki | | --- | --- | --- | | 2026-08-15T18:07:49Z → 2026-08-17T18:09:32Z | HEAD `297f106d` → `a4fa5a32` (**7 new commits**: `0fc8db24` + `290e9635` + `24c713de` + `4073abf4` Quintard 2024 Nat Commun microfluidic vascularized organoid chip 4-commit LDR cycle + `2e6f5989` + `00f824f2` + `a4fa5a32` Guo 2026 Front Cell Dev Biol organoid ethics systematic review 3-commit LDR cycle — **first time since the 2026-07-28 / 2026-07-29 Parate / Lee / Hodge cluster that two new paper deep-reads landed on `main` in the same 48-hour window**) | HEAD `2507925` → `be49285` (**4 new commits**: `151d22b` daily update 2026-08-16 + `997b648` sources-sync 2026-08-16 + `5c70881` daily update 2026-08-17 + `be49285` sources-sync 2026-08-17) | | 2026-08-17T18:09:32Z → 2026-08-18T18:10:12Z | HEAD **unchanged** at `a4fa5a32` (**0 new commits**, **0 new mtime changes** — vault is silent in this 24-hour window; the 2026-08-16 Quintard 2024 + Guo 2026 cluster remains the most recent vault activity) | HEAD `be49285` → `1fc73ae` (**2 new automated commits**: `8127797` chore: daily update 2026-08-18 + `1fc73ae` chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-18, the **fourth** consecutive sources-sync re-applying the `2507925` 2026-08-15 count-data wipe pattern)) | | 2026-08-19T18:08:24Z → 2026-08-20T18:09:15Z | HEAD **unchanged** at `a4fa5a32` (**0 new commits**, **0 new mtime changes** — vault is silent in this 24-hour window for the **4th consecutive fetch**; the 2026-08-16 Quintard 2024 + Guo 2026 cluster remains the most recent vault activity, **4 calendar days stale**) | HEAD `dcb53a2` → `bd30339` (**2 new automated commits**: `a44f284` chore: daily update 2026-08-20 + `bd30339` chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-20, the **sixth** consecutive sources-sync re-applying the `2507925` 2026-08-15 count-data wipe pattern after `997b648` 2026-08-16 + `be49285` 2026-08-17 + `1fc73ae` 2026-08-18 + `dcb53a2` 2026-08-19 + now `bd30339` 2026-08-20)) | | 2026-08-18T18:10:12Z → 2026-08-19T18:08:24Z | HEAD **unchanged** at `a4fa5a32` (**0 new commits**, **0 new mtime changes** — vault is silent in this 24-hour window for the **3rd consecutive fetch**; the 2026-08-16 Quintard 2024 + Guo 2026 cluster remains the most recent vault activity, **3 calendar days stale**) | HEAD `1fc73ae` → `dcb53a2` (**2 new automated commits**: `7e904ec` chore: daily update 2026-08-19 + `dcb53a2` chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-19, the **fifth** consecutive sources-sync re-applying the `2507925` 2026-08-15 count-data wipe pattern after `997b648` 2026-08-16 + `be49285` 2026-08-17 + `1fc73ae` 2026-08-18 + now `dcb53a2` 2026-08-19)) | | 2026-08-20T18:09:15Z → 2026-08-21T18:09:00Z | HEAD **unchanged** at `a4fa5a32` (**0 new commits**, **0 new mtime changes** — vault is silent in this 24-hour window for the **5th consecutive fetch**; the 2026-08-16 Quintard 2024 + Guo 2026 cluster remains the most recent vault activity, **5 calendar days stale**) | HEAD `bd30339` → `f6c2576` (**2 new automated commits**: `b6dc337` chore: daily update 2026-08-21 + `f6c2576` chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-21, the **seventh** consecutive sources-sync re-applying the `2507925` 2026-08-15 count-data wipe pattern after `997b648` 2026-08-16 + `be49285` 2026-08-17 + `1fc73ae` 2026-08-18 + `dcb53a2` 2026-08-19 + `bd30339` 2026-08-20 + now `f6c2576` 2026-08-21)) | | **Net new external evidence** | **2 new paper deep-reads** (from the 2026-08-15T18:07Z → 2026-08-17T18:09Z window): Quintard 2024 Nat Commun microfluidic vascularized organoid chip + Guo 2026 Front Cell Dev Biol organoid ethics systematic review. **2 new untracked directories** (from the same window): `celvivo_commercial/1331651_20260630_131201.pdf` (the 6-30 quote PDF migrated into a new folder) + `templates/类器官IRB申请清单.md` (the IRB application checklist derived from Guo 2026 — Robin's first customer-facing sales ammunition template produced from a single deep-read). The `Review/zhou2023_computer_vision_microfluidics.md` first-entry-in-Review/-subfolder is still untracked, carrying forward from the 2026-08-13 fetch (**10-day carry-forward** at the 2026-08-21T18:09Z fetch — was 9-day at the 2026-08-20T18:09Z fetch). **No new vault evidence in the 2026-08-20T18:09Z → 2026-08-21T18:09Z 24-hour window** | **1 new wiki file** (from the 2026-08-17 daily update `5c70881`): `sources/openwiki-version-drift.md` (auto-generated OpenWiki version-drift monitor; v0.3.1 local → v0.3.3 npm latest as of 2026-08-15T20:00:03Z). **Wiki-side**: the 2026-08-21T18:09Z fetch observed wiki HEAD bump `bd30339` → `f6c2576` — 2 new automated wiki commits (`b6dc337` daily update 2026-08-21 + `f6c2576` sources-sync 2026-08-21 — the **seventh** consecutive sources-sync re-applying the `2507925` 2026-08-15 count-data wipe pattern). Synthesis-layer edits accumulated across the prior HN-1 2026-08-13 + HN-1 2026-08-15 + HN-1 2026-08-16 + HN-1 2026-08-17 + HN-1 2026-08-18 + HN-1 2026-08-19 + HN-1 2026-08-20 + HN-1 2026-08-21 + web-search-1 2026-08-15 + web-search-1 2026-08-17 + web-search-1 2026-08-18 + web-search-1 2026-08-19 + web-search-1 2026-08-20 (skipped) + web-search-1 2026-08-21 (skipped) + git-repo-1 2026-08-13 + git-repo-1 2026-08-15 + git-repo-1 2026-08-17 + git-repo-1 2026-08-18 + git-repo-1 2026-08-19 + git-repo-1 2026-08-20 + this git-repo-1 2026-08-21 runs are pending the next CLI commit cycle | | Untracked → committed migrations | **Quintard 2024 file (4 commits)** + **Guo 2026 file (3 commits)** all moved from absent → committed on `main` (in the 2026-08-15T18:07Z → 2026-08-17T18:09Z window); **the 2 new untracked directories** are net-new in the same window. **None** in the 2026-08-17T18:09Z → 2026-08-18T18:10Z 24-hour window (vault silent) or the 2026-08-18T18:10Z → 2026-08-19T18:08Z 24-hour window (vault silent for the 3rd consecutive fetch) or the 2026-08-19T18:08Z → 2026-08-20T18:09Z 24-hour window (vault silent for the 4th consecutive fetch) or the 2026-08-20T18:09Z → 2026-08-21T18:09Z 24-hour window (vault silent for the 5th consecutive fetch). | **2026-08-15T18:07Z → 2026-08-17T18:09Z window**: the `sources/index.md` from the 2026-08-15 dirty set was committed by the 2026-08-16 daily update `151d22b`; the remaining 9 dirty files are uncommitted synthesis edits accumulated across the prior HN-1 + web-search-1 + git-repo-1 runs. **2026-08-17T18:09Z → 2026-08-18T18:10Z window**: the `8127797` 2026-08-18 daily update committed a subset of the synthesis-layer edits from the prior HN-1 2026-08-18T18:00Z + git-repo-1 2026-08-17T18:09Z runs (touching `commitments.md` + `index.md` + `quickstart.md` + `sources/{README,git-repo,hackernews,index,literature,nocodb,ragflow,seafile,web-search,wikijs}.md` + `themes/{01-organoid-equipment,05-robin-research}.md` per `git show --stat 8127797`); the 9 dirty files re-appear in the working tree because the very next synthesis edits from this git-repo-1 2026-08-18T18:10Z run re-touch the same files. **2026-08-18T18:10Z → 2026-08-19T18:08Z window**: the `7e904ec` 2026-08-19 daily update committed a subset of the synthesis-layer edits from the prior HN-1 2026-08-19T18:00Z + web-search-1 2026-08-19 + git-repo-1 2026-08-18T18:10Z runs (touching `.last-update.json` + `quickstart.md` + `sources/{README,git-repo,hackernews,index,nocodb,ragflow,seafile,web-search,wikijs}.md` + `themes/05-robin-research.md` per `git show --stat 7e904ec`); the 10 dirty files (`.last-update.json` + `quickstart.md` + `sources/{README,hackernews,index,nocodb,ragflow,seafile,web-search,wikijs}.md`) re-appear in the working tree because the very next synthesis edits from this git-repo-1 2026-08-19T18:08Z run re-touch the same files. **2026-08-19T18:08Z → 2026-08-20T18:09Z window**: the `a44f284` 2026-08-20 daily update committed a subset of the synthesis-layer edits from the prior HN-1 2026-08-20T18:00Z + web-search-1 2026-08-20 (skipped) + git-repo-1 2026-08-19T18:08Z runs; the 10 dirty files re-appear in the working tree because the very next synthesis edits from this git-repo-1 2026-08-20T18:09Z run re-touch the same files. **2026-08-20T18:09Z → 2026-08-21T18:09Z window**: the `b6dc337` 2026-08-21 daily update committed a subset of the synthesis-layer edits from the prior HN-1 2026-08-21T18:00Z + web-search-1 2026-08-21 (skipped) + git-repo-1 2026-08-20T18:09Z runs; **`sources/index.md` was committed by `b6dc337`** (was re-appearing as dirty since 2026-08-16 daily update). The 9 dirty files (`.last-update.json` + `quickstart.md` + `sources/{README,hackernews,nocodb,ragflow,seafile,web-search,wikijs}.md`) re-appear in the working tree because the very next synthesis edits from this git-repo-1 2026-08-21T18:09Z run re-touch the same files. The 9 dirty files are awaiting the next CLI commit cycle | | **Operational issue carried over from prior runs** | n/a | **`2507925` 2026-08-15 sources-sync bug** + the 2026-08-16 `997b648` + 2026-08-17 `be49285` + 2026-08-18 `1fc73ae` + 2026-08-19 `dcb53a2` + 2026-08-20 `bd30339` + 2026-08-21 `f6c2576` sources-syncs (which re-applied the same operational pattern as `2507925` — NocoDB / Wiki.js / RAGFlow count values stayed zero across all **7** sources-syncs). The on-disk `~/.openwiki/connectors/web-search/config.json` is unaffected — this is a wiki-side CRON issue with the auto-source-sync job, not a connector config issue. Recorded for traceability on `/sources/git-repo.md` Notable-entity § "2026-08-15 sources-sync bug" and on each affected `/sources/{nocodb,ragflow,seafile,wikijs}.md` page. The data is recoverable from `git show 8ddc6d9:sources/nocodb.md` etc. for any future recovery commit | ## Vault navigation index The vault uses a numbered top-level layout. Scripts, caches, and `temp*` working folders are excluded from this index. | Dir | Purpose | Size hint | | --- | --- | --- | | `01-Active-Sales/` | Active sales pipeline files (board + per-account) | 6 .md | | `02-Active-Deals/` | Deal-level active docs | 1 .md | | `02-Clients/`, `02-Contacts/` | Client & contact records | sparse | | `03-Product/` | Product briefs (e.g. 3Brain-Maxwell comparison) | 1 .md | | `03-Resources/Agents/` | Distributor / agent profiles | a handful | | `03-Resources/End-Customers/` | End-customer dossiers (3Brain MEA accounts, etc.) | 11+ .md | | `03-Resources/ITX-24h-Host/` | Personal 24h Hermes-Agent / AI-workflow host build config (2026-07-31 untracked; not yet on `main`) | 1 .md | | `04-Literature/` | Paper deep-reads + curated vendor PDFs | see breakdown | | `05-Documents/Contracts/` | Signed/pending contracts (Celvivo subfolder) | — | | `05-Documents/Products/` | Vendor-facing product docs (Celvivo/Industrial-Customers) | — | | `05-Documents/{Proposals,Quotes,Visit-Plans}/` | Active commercial docs | — | | `05-Products/` | In-house product briefs (MappingLab family) | 2 .md | | `06-Sales/Competitors/` | Competitor tracking | — | | `06-Sales/Configurations/` | Product configurations | — | | `06-Sales/Content/{FAQ,Pain-Points,PPT-Scripts,Success-Stories,Training-Materials,推文模板}/` | Sales content library | — | | `06-Sales/{Price-List,Product-Mapping,Recommendation-Engine}/` | Sales tooling | — | | `99-Templates/` | Reusable Obsidian templates | 14 .md | | `memory/` | Daily reports, weekly digests, `.dreams`, archive | 147 .md | ### `04-Literature/Deep-Reads/` breakdown Markdown file counts per deep-read subfolder: | Subfolder | .md count | | --- | --- | | `Organoid/` | 661 (+2 from 2026-08-16 — Quintard 2024 Nat Commun microfluidic vascularized organoid chip + Guo 2026 Front Cell Dev Biol organoid ethics systematic review) | | `Celvivo/` | 142 | | `3Brain/` | 136 | | `Cellink/` | 129 | | `Organoid-List/` | 51 | | `Product-Reports/` | 38 | | `Brain/` | 11 | | `Brain-Tumor/` | 9 | | `Cancer/` | 6 | | `Liver/` | 6 | | `Other/` | 6 | | `RegenMed/` | 1 | | `3Brain MEA/` | 3 | | `Cardiac/` | 2 | | `Kidney/` | 2 | | `Retinal/` | 1 | | `Microbioreactor/` | 1 (new as of 2026-08-07 — Rosero 2026 Front Bioeng Biotechnol) | | `Cells/` | 1 (new as of 2026-08-08 — Fernandez Vallone 2026 Cells THSDC) | | `Review/` | 1 (new as of 2026-08-13 — Zhou 2023 computer vision + microfluidics, **untracked**, **8-day carry-forward** at 2026-08-19 fetch, **6 fetches silent** — structural signal continuing to weaken) | | `templates/` | 1 (new as of 2026-08-17 — `类器官IRB申请清单.md`, derived from the Guo 2026 ethics deep-read; Robin's first customer-facing template produced from a single deep-read, **untracked**, **4-day carry-forward** at 2026-08-20 fetch (was 3-day at 2026-08-19) | | `celvivo_commercial/` | 1 (new as of 2026-08-17 — `1331651_20260630_131201.pdf`, the 6-30 quote PDF migrated into a new folder, **untracked**, **4-day carry-forward** at 2026-08-20 fetch (was 3-day at 2026-08-19) | Total ≈ 1,207 deep-read notes on `main` (+2 from the 2026-08-16 Quintard 2024 + Guo 2026 clusters). Review/ zhou2023 computer vision + microfluidics, **untracked** — only counts once committed; +2 working-tree files in the new `templates/` + `celvivo_commercial/` directories, both untracked). The 2026-08-16 Quintard 2024 + Guo 2026 cluster is the most recent committed deep-read additions; the 2026-08-07 / 2026-08-08 cluster (Microbioreactor + Cells) remains the prior committed cluster. CelVivo, 3Brain, Cellink, and the broad `Organoid/` bucket cover Robin's product KB per the wiki goal focus areas (类器官培养与设备, 3D 生物打印). The new `templates/` folder signals Robin may be formalizing customer-facing deliverables (checklists / templates / sales scripts) as a separate vault subtree — the IRB application checklist is the first such artifact. ## Distributor map refresh (2026-08-07) Robin uploaded a refreshed `b7f52af896c1e3a9.xlsx` on 2026-08-07 11:11, producing **8 new `*2026-0807.md` regional files** + a new `全国经销商地图-2026-0807.md` index + a new **product-association index** (`_known_associations.md`) + a new `_meta.json` reflecting the 259-dealer tally. The 2026-07-24 baseline (`*2026-0724.md` × 7 + index) remains in the repo but is now stale. What changed in the 2026-08-07 baseline vs the 2026-07-24 baseline: | Dimension | 2026-07-24 (`_meta.json`) | 2026-08-07 (`全国经销商地图-2026-0807.md`) | | --- | --- | --- | | Total dealers | 261 (明细表口径) | 259 (公司数量汇总) | | xlsx sha256 | `3afd448edcf3a9673848da0de2c554e6a4b22d7329b988695ca242c8bc8c10cf` | (re-uploaded with 8-04 同名 + 新增 2-3 家) | | Region table | 华北 74 / 华东 68 / 华南 62 / 山东 25 / 湖北 19 / 西北 6 / 西南 7 | 华北 72 / 华东 68 / 华南 62 / 山东 25 / 湖北 19 / 西北 6 / 西南 7 | | 华北 count | 74 | 72 (-2) | | Hook 4 output | (none) | 4 dealer-management hooks + `_known_associations.md` | The numeric 261 vs 259 difference is still rooted in the **华北 表 74 vs 汇总 72** discrepancy (two unnamed companies — 序号 63 / 67 — leave the 明细表 2 rows above the 汇总表); the 2026-08-07 baseline carries the same data anomaly plus a new structural artifact: **济南成全生物科技 (曹沛起) is registered in both `华北-2026-0807.md` and `山东-2026-0807.md` (legitimate cross-region duplicate)** — this is the only CelVivo ClinoStar agent in the 259-dealer list and is the thread Robin should follow to close the `agent-dong-huiqun-celvivo` open question. ### `_known_associations.md` (2026-08-07) — product → dealer mapping The new index file `02-Clients/Agents/_known_associations.md` is the canonical hook-4 output Robin needs to evaluate before the next Chinese-region dealer visit. Key mappings surfaced (5 direct hits): | Product line | 261-dealer表 命中 | 关联客户 / 商机 | | --- | --- | --- | | **CelVivo (ClinoStar / ClinoReactor)** | **济南成全生物科技有限公司 (曹沛起)** — registered in both 华北 + 山东 (cross-region, 2 次) | 董慧群关联 (待 Robin 确认是否同公司) | | **FemtoBiomed (CellShot / PROLIVA)** | 0 direct hits (9X Bio / 汇佰生物 is the direct intermediate, not in the 261 dealer list) | TriArm Therapeutics (翁靖傑, 上海 CGT/CAR-T) — 128 万 Phase1 / 8-10 至 8-14 现场 demo | | **3Brain (HD-MEA)** | 0 direct hits | — | | **Cellink (BIO X)** | 0 direct hits | — | | **西南医大 心研所 殴贤红** | 2 dealers: 成都百乐 (杨军, 钻石级 1亿, Bio-Rad / Sartorius / Oxford Nanopore / Cytek / Leica, 覆盖川渝黔藏) + 成都立德赛 (川渝云贵陕) | (待 Robin 决策) | **Hook-4 questions** (Robin 优先补全, per `_known_associations.md`): 1. 董慧群 is which specific technical contact at 济南成全 — or is she at a different CelVivo-代理? 2. 西南医大 殴贤红 → 成都百乐 vs 成都立德赛 — which dealer first? 3. 邓昊伦 (02-Contacts/) 蛇类神经方向 → 3Brain HD-MEA 拜访? 4. 261 dealer 表 has 0 3Brain / Cellink 代理 — is the dealer list incomplete, or does Robin need to actively recruit those dealers? Log these as a new commitment on `/commitments.md` (`distributor-8-07-association-followup`) and as updates to `/open-questions.md` (the `agent-dong-huiqun-celvivo` question now **partially answered** — agency identified but personal contact fields still 待补). ## Notable entities surfaced by the vault (structural hints only) - **Quintard 2024 Nat Commun microfluidic vascularized organoid chip (2026-08-16, 7 commits in 48-hour window)** — `obsidian-vault/Literature/Deep-Reads/Organoid/quintard_2024_vasorganoid_chip.md` (189 lines; 4-commit LDR cycle `0fc8db24` adds → `290e9635` -v2 修图床/双 H1/落款 → `24c713de` -v3 Wiki.js 自带图床 6 张图 → `4073abf4` -v4 转发语标题/落款加粗/删 3Brain; Wiki IDs 1719/1720/1722, NocoDB Id 3297). The paper is **the first microfluidic / organ-on-chip platform paper** Robin has deep-read in the 2026-08 window; the platform combines (i) 10-channel parallel microfluidic chips with U-shaped capture sites (300-800 µm adjustable), (ii) fibrin + Matrigel hydrogel layer deposition using Landau-Levich-Bretherton effect, (iii) ~10 s capture efficiency ~100%, (iv) dynamic perfusion 7-30 days with HUVEC + fibroblast co-culture + hiPSC-derived BVO + islet spheroid + lung organoid cross-validation, (v) hierarchical vasculature (37 µm upstream artery-vein + 8 µm BVO capillaries, matching physiological ranges 50-1900 s⁻¹). **Net-new external evidence** in this run (git-repo-1 2026-08-17). The 4-star "与我们的产品" table lists **Mimetas OrganoPlate ⭐⭐⭐⭐** (direct Phaseguide-based vascularized / kidney / intestine organ-on-chip competitor) + **CelVivo ClinoStar ⭐⭐⭐** (upstream workflow step: BVO differentiation day 0-15 needs rotating-wall suspension culture; ClinoStar is the canonical hardware for this stage; the paper's day 15 → chip-on-board handoff is the canonical CelVivo → organ-on-chip workflow) + **Emulate Organ-Chip ⭐⭐⭐** (Colon-Intestine-Liver platform companion). Synthesis routes into `/themes/05-robin-research.md` (新增 by-vendor entry) and `/sources/literature.md` (last-30-days deep-read table). Vendor-anchor mapping: CelVivo-adjacent (workflow upstream) + Mimetas OrganoPlate / Emulate Organ-Chip (organ-on-chip product lane that Robin's portfolio does not currently cover but represents a potential cross-sell if Robin's customers ask "where do I run my CelVivo-matured organoids in a vascularized microenvironment?"). Customer-entry: 药企临床前 (vascularized drug screening) + 微流控 organ-on-chip 平台集成商 (Mimetas / Emulate channel partners) + academic PI (vascular development / diabetes). **Track on next fetch** whether Robin publishes a `/sources/literature-quintard-2024-nat-commun-vasorganoid-chip-deepread.md` synthesis page; the deep-read pipeline currently only carries `liang-2026-celvivo-clinostar-positioning` + `miao-2025-celvivo-clinostar-positioning` + `liu-2026-hd-mea-roadmap-implication` + `sharma-2026-retinal-organoid-mea-cross-sell` — no Quintard synthesis page yet. - **Guo 2026 Front Cell Dev Biol organoid ethics systematic review (2026-08-16, 7 commits in 48-hour window)** — `obsidian-vault/Literature/Deep-Reads/Organoid/guo_2026_organoid_ethical_review.md` (170 lines + 3 真图; 3-commit LDR cycle `2e6f5989` adds → `00f824f2` -v2 修图床 (加 2 张 Wiki.js 自带图) → `a4fa5a32` -v3 补 Fig 1; Wiki ID 1724, NocoDB Id 3298). The paper is **the first organoid-research ethics / IRB systematic review** Robin has deep-read in any window — fills the methodological gap on the IRB-side that the prior clinical-translation evidence (CDE classification + Order No. 818) does not directly cover. The paper structures the IRB review framework as **7 mandatory points** (sample provenance + donor informed consent + data privacy & de-identification + co-culture agency + animal welfare 3R + cross-border regulation + long-term storage & termination); the cross-border table compares China (《人类遗传资源管理条例》+ 《涉及人的生命科学和医学研究伦理审查办法》2023), US (HIPAA + Common Rule + NIH GDS), EU (GDPR + Clinical Trials Regulation 536/2014), Japan, Korea. The 4-star "与我们的产品" table lists **CelVivo ClinoStar ⭐⭐⭐⭐** (clinical-translation IRB compliance — the 7 mandatory points directly apply to ClinoStar customer IRB submissions; **Robin 推广 ClinoStar 给三甲医院时, 可附带本框架作为增值**) + **Mimetas OrganoPlate ⭐⭐⭐⭐** (co-culture ethics — Mimetas 主营类器官 + 免疫细胞共培养, the co-culture agency framework from Guo 2026 point 4 directly applies) + **Emulate Organ-Chip ⭐⭐⭐** (organoid + microfluidic cross-border regulation reference). **Net-new external evidence** in this run (git-repo-1 2026-08-17). Robin translated the paper into a **customer-facing sales ammunition template** at `templates/类器官IRB申请清单.md` (180 lines; 7 mandatory points checklist + 5 customer Q&A + China vs International flow table + 10 attachments + 7 citations; v1.0 dated 2026-08-16, "Robin 8-16 实战沉淀") — see the templates/ entry in the next bullet. Customer-entry: 临床转化型医院 (class A tertiary hospitals running organoid IRB submissions) + 类器官厂家 Robin 培训客户 (the IRB checklist is the canonical "Robin 培训客户 IRB 申请" core material) + academic PI (cross-border collaboration IRB paperwork). **Track on next fetch** whether (a) the templates/ IRB checklist gets committed, (b) the Robin-author attribution in the template is recognized as a wiki-side customer-training artifact, (c) Robin produces a deep-read synthesis page at `/sources/literature-guo-2026-front-cell-dev-biol-organoid-ethics-deepread.md`, and (d) the IRB checklist routes into the existing CelVivo industrial-customers program (which currently lives at `05-Documents/Products/Celvivo/Industrial-Customers/`) as a standard customer-training artifact. - **Review/ subfolder — first entry (2026-08-13, still uncommitted at 2026-08-21, 10-day carry-forward, watchlist signal continuing to weaken)** — `obsidian-vault/04-Literature/Deep-Reads/Review/zhou2023_computer_vision_microfluidics.md` is the **first file in a new `Review/` subfolder** under `04-Literature/Deep-Reads/`. The file is **untracked** at the 2026-08-21 fetch (Robin has not yet committed it — same state as the 2026-08-13 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 fetches, **0 progress in the 2026-08-13 → 2026-08-21 192-hour window**, **8 consecutive fetches silent on the file**). **Watchlist signal continuing to weaken at this fetch**: per the 2026-08-15 watchlist-trigger rubric ("if the file remains uncommitted at the next fetch (2026-08-17 or later), the structural signal weakens"), the `Review/` subfolder at the 2026-08-21 fetch is **still single-entry, still untracked** — the structural signal **continues to weaken** at this fetch (**10-day carry-forward** with no commit, no follow-up paper landed in the subfolder across **8 consecutive fetches**). The `Review/` subfolder is more likely to be a one-off than a recurring pattern. The file should either be committed on a future fetch (which would re-strengthen the signal) or remain untracked indefinitely (which would confirm the one-off interpretation). No synthesis routes until the file is committed. - **`templates/` subfolder — first entry (2026-08-16, NEW this run)** — `templates/类器官IRB申请清单.md` (180 lines, mtime 2026-08-16, untracked) is the **first file in a new `templates/` directory** at the vault root. The file is Robin's **first customer-facing sales ammunition template produced from a single deep-read** (the Guo 2026 IRB ethics systematic review). Content: 7 mandatory IRB review points checklist (样本来源/知情同意/数据隐私/共培养主体性/3R 动物福利/跨境监管/长期保存与终止使用) + 5 customer Q&A ("类器官研究要不要 IRB 申请?" / "类器官共培养产品怎么申请 IRB?" / "类器官跨境研究怎么报?" / "3R 原则怎么写?" / "类器官 + 免疫细胞共培养 = CAR-T 体外培养, 算不算新生物体? 伦理上算什么?") + China vs International flow comparison table + 10-row 申请附件清单 + 7 references (Guo 2026 + ISSCR 2021 + OHRP 2016 + GDPR 2018 + China 2023 + China 2019 + Cambridge 2020). The template's `version: v1.0 (2026-08-16, Robin 8-16 实战沉淀)` and `Robin 业务定位: 类器官厂家给三甲医院 IRB 申请的标准模板 + Robin 客户培训材料核心` framing makes it explicit that this is the canonical "Robin 培训客户 IRB 申请" core material. **Structural significance**: the `templates/` directory is new — none of the existing top-level folders (`01-Active-Sales/` / `02-Clients/` / `02-Active-Deals/` / `02-Contacts/` / `03-Product/` / `03-Resources/` / `04-Literature/` / `05-Documents/` / `06-Sales/` / `99-Templates/` / `memory/`) provides a vendor-agnostic customer-training-artifact slot at the vault root. The Obsidian vault already has `99-Templates/` for reusable Obsidian templates (note templates, daily-report templates — per `99-Templates/` size hint 14 .md), but the new `templates/` directory is **for customer-facing sales ammunition**, not Obsidian note templates — a different artifact type. The naming convention overlaps with `99-Templates/` and may need disambiguation; Robin's intent (per the file header) is for this `templates/` to be the **canonical customer-training artifact directory**, distinct from `99-Templates/` Obsidian-note templates. **Customer-entry scenarios** called out in the template: (a) 类器官厂家研发负责人 = IRB 申请准备, (b) Robin 客户开发 = 培训客户 IRB 申请核心材料, (c) 医院 IRB 委员会 = 类器官研究 IRB 审查标准参考, (d) 学术合作方 = 跨境合作时多国法规差异对照. **Carry-forward status** (2026-08-21): untracked, **5-day carry-forward** since first observation (2026-08-17 fetch — was 4-day at the 2026-08-20 fetch), future-commit candidate. **Track on next fetch** whether (a) Robin commits the file to `main`, (b) more templates land in the directory (extending the customer-training-artifact slot), (c) the `templates/` and `99-Templates/` naming overlap gets resolved (rename / docs / conventions). Synthesis routes into `/themes/05-robin-research.md` (sales ammunition pipeline section). - **`celvivo_commercial/` subfolder — first entry (2026-08-17, NEW this run)** — `celvivo_commercial/1331651_20260630_131201.pdf` (56 KB PDF, mtime 2026-08-17, untracked) is the **first file in a new `celvivo_commercial/` directory** at the vault root. The PDF is the existing 6-30 quote PDF that Robin migrated into a new folder. The file is **a quote PDF**, not a synthesis target — the on-disk evidence is the existing 6-30 quote document that already exists in `05-Documents/Products/Celvivo/Industrial-Customers/` (per the 2026-08-15 synthesis-policy section above, "commercial docs (8 files: Exhibit 1 Price Book / Exhibit 3 SuperUser certification / Huibai demo discount agreement / 惠百 PO 盖章版 / Celvivo Distribution Agreement 2026 Huibai Bio / 1331651_20260630_131201 (6-30 quote) / Packing Slip Ordre 726_1 / Packing Slip Ordre 726_2)"). **Structural significance**: the `celvivo_commercial/` directory is new — Robin has migrated the 6-30 quote out of wherever it was previously (presumably a working folder or `05-Documents/Products/Celvivo/` deep path) into a top-level dedicated directory. **The migration is unfinished** — only 1 file in the new directory; if Robin intends the directory to consolidate all 8 commercial docs from `05-Documents/Products/Celvivo/Industrial-Customers/`, the other 7 files (Exhibit 1 Price Book / Exhibit 3 SuperUser certification / Huibai demo discount agreement / 惠百 PO 盖章版 / Celvivo Distribution Agreement 2026 / Packing Slip Ordre 726_1 / Packing Slip Ordre 726_2) should eventually land here too. **No synthesis routes** until Robin commits the file or migrates more docs into the directory. Carry-forward status (2026-08-21): untracked, single-entry, **5-day carry-forward** since first observation (2026-08-17 fetch — was 4-day at the 2026-08-20 fetch), future-commit candidate. Track on next fetch whether (a) the file gets committed, (b) more commercial docs migrate into the directory. - **2026-08-15 sources-sync bug — count-data wipe (operational)** — the `2507925e27b83b4f9d2e6f3b9c939d081a90f9f2` `chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-15)` commit at 2026-08-15 +0800 02:31 committed **empty count values** for NocoDB / Wiki.js / RAGFlow (SeaFile was already empty so the commit was a no-op there): (a) NocoDB: 6614 → **0** total records, with all 13 per-table counts (brain_organoid_literature / intestinal_organoid_literature / Celvivo_literature / cardiac_organoid_literature / cancer_organoid_literature / liver_organoid_literature / other_organoid_literature / kidney_organoid_literature / retinal_organoid_literature / Cellink_literature / organoid_literature_old / lung_organoid_literature / 3Brain_literature) cleared to empty cells; (b) SeaFile: libraries table unchanged (was empty in `1737454` already — a separate, older cron issue not introduced by `2507925`); (c) Wiki.js: 83 → **0** unique pages, ID range 22..1704 → **0..0**, Locale 分布 → empty, Top-level 路径分布 → empty; (d) RAGFlow: landing 200 → **000**, `/api/v1/health` 404 → **000**, `/api/v1/datasets` 401 → **000**. The header lines on each affected `/sources/{nocodb,ragflow,seafile,wikijs}.md` page still report `上次同步: 2026-08-14T18:30:42Z` (the prior successful sync timestamp), but the body count values are wiped. **Probable root cause**: the auto-source-sync CRON job ran but the underlying NocoDB / Wiki.js / RAGFlow API calls failed (likely the same operational issue already documented on `/sources/web-search.md` and `/sources/README.md` — runtime registry disagreement on `enabled: true` vs. disabled); the script committed the empty values instead of skipping the commit on failure. **Impact**: 3 source pages now show misleading zero/null values (NocoDB / Wiki.js / RAGFlow); Tavily / HN / git-repo synthesis is unaffected. **Recovery**: the wiped data is recoverable from the prior wiki commit (`git show 1737454:sources/nocodb.md` etc. will restore the pre-wipe state). This run restored the wiped data on all 3 affected pages (plus an operational note documenting the bug) so the wiki is internally consistent again. **Wiki-synthesis concern**: **none** — the synthesis layer (themes / commitments / open-questions / personal-logistics) is independent of the source-page counters. **Operational concern**: **yes** — the auto-source-sync job should (a) check connectivity before committing, (b) skip the commit on API failure rather than committing empty values, or (c) preserve the prior counter values when a fresh pull returns null/empty. Recorded for traceability here + on each affected `/sources/{nocodb,ragflow,seafile,wikijs}.md` page. - **Liang 2026 liver organoid fibrosis platform (2026-08-12)** — `04-Literature/Deep-Reads/Liver/2026-08-12_Liang_2026_SciRep_liver_organoid_fibrosis_platform.md` (170 lines; `[[MOC-类器官与3D培养]]` already names this paper via `related:` back-link). The paper is **the net-new external evidence** this run (git-repo-1 2026-08-12) brought into the vault; see synthesis at `/themes/01-organoid-equipment.md` § CelVivo evidence (added 2026-08-12) and `/commitments.md` `liang-2026-celvivo-clinostar-positioning`. Single-paper LDR cycle: 4 commits (`e542c977` → `8699a154` → `aacba7aa` → `297f106d`) walked Robin's standard 3-stage SOP on the same file (186 lines → 105+/122- page 946 rewrite → page 934 修齐 micro-revisions). The 4-star "与我们的产品" table on the paper lists **CelVivo ClinoStar ⭐⭐⭐⭐** (P1-P10 长程扩增对应旋转培养 30+ 天无剪切; HSC 静止态在模拟微重力下 7+ 天维持) + **CelVivo ClinoReactor ⭐⭐⭐⭐** (单组织 3 轨道分通道灌流; TGFβ 时间程序精确切换) — **parallel CelVivo ClinoStar rating 5 to Miao 2025 v2's ClinoStar rating 5** from the 2026-08-08 flywheel-sync, but for liver organoid (long-term maturation + fibrosis modeling) rather than lung organoid (vascularization). 7 SeaFile Fig (Fig1-7) + 4-paper 参考文献 (Huch 2013 / Huch 2015 / Clevers 2016). Customer-entry: 药企临床前 (抗纤维化药筛) + 临床肝活检中心 (1-2 mg → 3 周药敏) + 学术 PI (2D vs 3D 旋转 efficiency). **MOC linkage**: the paper's `related:` field already names `[[MOC-类器官与3D培养]]` (the first MOC, created 2026-08-10) — confirming the MOC pattern is in active use on real deep-reads. - **CelVivo industrial customers program** — a dedicated subfolder under `05-Documents/Products/Celvivo/Industrial-Customers/` holds `CelVivo_中国工业 客户开发研究报告` (v1 + v2), `客户管线定位_1页图`, and `工业客户开发手册-v3`. This is a self-contained CelVivo China commercial effort. - **CelVivo sales training cluster** — `06-Sales/Content/Training-Materials/` contains a `Robin稿生成通字稿` family (v3–v6), a `CelVivo赋能培训` PowerPoint family (v1–v9, depth-flavored edits), and a `销售基础话术包` pair. Versions progress from 基础 → 5大管线 → 深度版 → 终稿修正 → 销量仅看. - **3Brain end-customer dossier set** — 11+ dossiers under `03-Resources/End-Customers/` covering 神经所 (上海), 北京大学, 北京天坛医院, 浙大一附院, 中科院昆明动物所, 西南医科大学, 贵州医科大学, plus TCM accounts at 云南中医药大学 and 天津创新中药. - **CelVivo distributor technical contact (2026-07-28, partially resolved 2026-08-07)** — `02-Clients/Agents/董慧群.md` is the first profile under the `02-Clients/Agents/` bucket (frontmatter `type: agent`, role: 代理商技术同事, products: CelVivo ClinoStar / ClinoReactor). The 2026-08-07 `_known_associations.md` index now identifies the CelVivo dealer as **济南成全生物科技 (曹沛起)** — the only ClinoStar agent in the 259-dealer list, registered in both 华北 + 山东. Robin still needs to confirm: (a) is 董慧群 the same agency? (b) phone / WeChat / served end-customers / opportunities. The agency-side gap is now closed. - **ITX 24h host build (first observed 2026-07-31; still untracked)** — `03-Resources/ITX-24h-Host/ITX_24h_Host_v18_Config_2026-07-31.md` is a top-level bucket first observed between the 2026-07-30T18:13 fetch and the 2026-07-31T18:08 fetch; it remains untracked. Single file: Robin's personal 24h server build plan for hosting Hermes Agent + AI workflow stack — mATX + i5-12400 + DDR4-2666 32G + 板载 Realtek 1Gb + Intel PRO/1000 GT 双网卡 NAS 隔离, ¥2,985.82, 10/11 parts arrived, planned hostnames/roles: 192.168.31.100 (主力机 SSH) vs 10.10.10.254 (RAGFlow / NAS RAGFlow API). Workflow-tooling priority LOW (not vendor-anchored), so it does **not** earn a `/themes.md` row, but the build remains a source-anchored personal-infra work item and was promoted to `/commitments.md` as `itx-24h-host-build-2026-q3` (Owner: me) for the post-assembly steps (Ubuntu Server 22.04 install + 双网卡静态 IP + Hermes Agent install + 24h soak test). - **Cells + 2026-08-08 cluster** — Fernandez Vallone 2026 Cells (hiPSC brain organoids for THSDC chemical screening, NAMs platform) is the first `04-Literature/Deep-Reads/Cells/` entry. New application domain (toxicology + NAMs) compared to the prior Brain / Cancer / Liver buckets. CelVivo + 3Brain application scenarios called out in tags. - **Microbioreactor + 2026-08-07 cluster** — Rosero 2026 Front Bioeng Biotechnol Microbioreactor design Mini Review is the first `04-Literature/Deep-Reads/Microbioreactor/` entry. Cross-vendor adjacent (CelVivo ClinoStar / Cellink BIO X / FemtoBiomed CellShot). Landed in NocoDB `Robin_Picked_Papers` (PMID 42516424, Wiki.js ID 1696). - **Parfitt 2024 Nat Commun (DJ1 LOF midbrain organoid + PD)** — untracked file `04-Literature/Deep-Reads/Brain/2026-08-06_Parfitt_GM_et_al_NatCommun_2024_DJ1_LOF_midbrain_organoid_PD.md` (15,972 bytes, mtime 2026-08-06). DJ1 LOF through astrocyte lysosomal dysfunction → AGE → α-syn → DA neuron death; CelVivo + 3Brain application scenarios in tags. Not yet on `main`; pending Robin commit. - **CellSweep** — referenced in the wiki goal focus areas; not surfaced as a top-level vault folder in this run, so it likely lives under `Work/` or `scripts/` (outside the navigation index). - **Phase A metadata batch + first MOC (2026-08-10)** — Robin ran a frontmatter-hygiene + MOC-discipline sprint on 2026-08-10: (a) **`d97b39ed` Phase A 批量** standardized 6 deep-read notes with the 6-field frontmatter (doi / journal / year / **volume** / **pages** / **authors** array / pmid) — `Organoids 2026 review` + `CelVivo PAH Metabolomics` + `Shin 2024 thalamocortical organoids 22q11ds` + `Fernandez Vallone 2026 Cells THSDC` + `Liu 2026 NBME shape-conformal organoid` + `类器官综述_CMOS_HD_MEA_类器官电生理_2026-06-05`; (b) **`6b717aef` MOC 方案 1 样品** created the **first MOC** at `04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md` (95 lines, 沙牛《AI 时代的 Obsidian 公开课》课时 1 pattern, `type: moc`) and added `related:` back-link frontmatter to 7 papers; (c) **`3b929c2f` wang2024 方案 2 样品** added 7 image alt descriptions on top of the 6-field frontmatter for `wang2024-org-on-chip.md`. The MOC's own `related:` list already names `[[MOC-3Brain-HD-MEA]]` as the next planned MOC, plus `[[02-Clients/Agents/_known_associations]]` and `[[02-Active-Deals/CellShot-TriArm-Demo-计划-v2-老师版-2026-07-20]]`, so the pattern is expected to extend. None of the changes add new external evidence — the 6 papers already existed on `main`; this commit set only normalizes their metadata and cross-references. The MOC creation is the first durable structural artifact on the knowledge-graph side and is worth tracking on the next git-repo fetch. ## Synthesis policy for this source - **This run (2026-08-21, git-repo-1 18:09Z):** **0 new vault commits** in the 2026-08-20T18:09Z → 2026-08-21T18:09Z 24-hour window — the vault HEAD is **unchanged at `a4fa5a32`** for the **5th consecutive fetch** (the 2026-08-16 Quintard 2024 Nat Commun 4-commit LDR cycle + Guo 2026 Front Cell Dev Biol 3-commit LDR cycle remain the most recent vault activity, **5 calendar days stale** at this fetch). **0 new vault mtime changes** — the 2 untracked directories (`celvivo_commercial/` + `templates/`) and the 23+ untracked files from the 2026-08-17T18:09Z fetch carry forward unchanged. The `Review/zhou2023_computer_vision_microfluidics.md` first-entry in the new `Review/` subfolder is **10-day carry-forward** at this fetch (uncommitted since 2026-08-11); the structural signal for `Review/` continues to weaken per the Notable-entity entry (the subfolder has been a single-entry watchlist since 2026-08-13, now **8 fetches silent**). Wiki-side: **2 new automated wiki commits** landed in the 24-hour window — `b6dc337` chore: daily update 2026-08-21 (2026-08-21 02:27 +0800) + `f6c2576` chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-21, 2026-08-21 02:30 +0800) — advancing wiki HEAD from `bd30339` (2026-08-20T18:09Z fetch) to `f6c2576`. Both commits are routine auto-orchestration: (a) the `b6dc337` daily update carried the synthesis-layer edits from the prior HN-1 2026-08-21T18:00Z + web-search-1 2026-08-21 (skipped) + git-repo-1 2026-08-20T18:09Z runs; the `b6dc337` daily update committed `sources/index.md` from the 2026-08-20 dirty set (reducing uncommitted-file count from 10 → 9 at this fetch); (b) the `f6c2576` sources-sync re-applied the count-data wipe pattern on NocoDB / SeaFile / Wiki.js / RAGFlow for the **seventh** consecutive sources-sync (after 2026-08-15 `2507925` + 2026-08-16 `997b648` + 2026-08-17 `be49285` + 2026-08-18 `1fc73ae` + 2026-08-19 `dcb53a2` + 2026-08-20 `bd30339`). **No new external evidence** in this run (vault silent), **no new theme row**, **no new commitment row**, **no new open-question row**, **no new personal-logistics item** — the synthesis layer is unchanged. Wiki edits this run: (a) `/sources/git-repo.md` (this page) — refreshed frontmatter HEAD pointers (vault HEAD unchanged at `a4fa5a32`, wiki HEAD `bd30339` → `f6c2576`, tags + `2026-08-21`, timestamp → `2026-08-21T18:09:00Z`), refreshed the Connector / State section to the new `2026-08-21T18-08-59-795Z` raw manifest, refreshed the obsidian-vault working-tree-status section to 2026-08-21 (0 new commits, 0 new mtime changes, untracked set unchanged; `Review/` 9-day → 10-day + `templates/` + `celvivo_commercial/` 4-day → 5-day carry-forward), refreshed the openwiki-wiki working-tree-status section to 2026-08-21 (2 new automated wiki commits + 9 uncommitted synthesis-layer edits, down from 10 because `sources/index.md` was committed by `b6dc337`), added 2 new entries at the top of the Recent-commits-for-wiki table (`f6c2576` sources-sync 2026-08-21 + `b6dc337` daily update 2026-08-21), refreshed the Summary-of-last-48-hours table to add the 2026-08-20T18:09Z → 2026-08-21T18:09Z window data (0 vault commits / 2 wiki commits / operational row noting the **seventh** consecutive sources-sync re-applying the count-data wipe pattern), refreshed the Notable-entity `Review/` entry (9-day → 10-day carry- forward, **7 fetches silent** → **8 fetches silent**) + bumped `templates/` + `celvivo_commercial/` 4-day → 5-day, refreshed the Synthesis-policy section with this run's delta summary; (b) `/themes/05-robin-research.md` — vault-snapshot metadata refreshed (fetch timestamp → `2026-08-21T18:09:00Z`, raw-manifest path → the new `2026-08-21T18-08-59-795Z` manifest); the vault HEAD pointer stays `a4fa5a32` (unchanged across the 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 fetches); `Review/` 9-day → 10-day carry-forward; `Templates/` + `CelVivo-commercial/` 4-day → 5-day; (c) `/quickstart.md` — added the "Latest update — git-repo-1 (2026-08-21T18:09Z)" paragraph; updated the Backlog git-repo entry to reflect the new wiki HEAD `f6c2576` + 2 new automated wiki commits + 9 uncommitted synthesis-layer edits (down from 10) + the **seventh** consecutive sources-sync note; (d) `/sources/README.md` — refreshed Active connectors Git repo row + Connector roll Git repo row to mention the 2026-08-21 18:09 UTC fetch + the **seventh** consecutive sources-sync. **No `/themes.md` row change, no `/commitments.md` row, no `/open-questions.md` row, no `/personal-logistics.md` item** — the vault delta is empty and the wiki delta is automated maintenance only. The "vault is silent on a 24-hour window" pattern continues to be normal cadence for Robin's workflow (the 2026-08-13 + 2026-08-15 + 2026-08-18 + 2026-08-19 + 2026-08-20 fetches were also 0-new-vault-commits daily-cycle follow-ups; the 2026-08-21 fetch makes it **6 consecutive 0-new-vault-commit fetches**). The synthesis layer (themes / commitments / open-questions / personal-logistics) is independent of the wiki-side automated maintenance commits. - **Previous run (2026-08-20, git-repo-1 18:09Z):** **0 new vault commits** in the 2026-08-19T18:08Z → 2026-08-20T18:09Z 24-hour window — the vault HEAD is **unchanged at `a4fa5a32`** for the **4th consecutive fetch** (the 2026-08-16 Quintard 2024 Nat Commun 4-commit LDR cycle + Guo 2026 Front Cell Dev Biol 3-commit LDR cycle remain the most recent vault activity, **4 calendar days stale** at this fetch). **0 new vault mtime changes** — the 2 untracked directories (`celvivo_commercial/` + `templates/`) and the 23+ untracked files from the 2026-08-17T18:09Z fetch carry forward unchanged. The `Review/zhou2023_computer_vision_microfluidics.md` first-entry in the new `Review/` subfolder is **9-day carry-forward** at this fetch (uncommitted since 2026-08-11); the structural signal for `Review/` continues to weaken per the Notable-entity entry (the subfolder has been a single-entry watchlist since 2026-08-13, now **7 fetches silent**). Wiki-side: **2 new automated wiki commits** landed in the 24-hour window — `a44f284` chore: daily update 2026-08-20 (2026-08-20 02:23 +0800) + `bd30339` chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-20, 2026-08-20 02:30 +0800) — advancing wiki HEAD from `dcb53a2` (2026-08-19T18:08Z fetch) to `bd30339`. Both commits are routine auto-orchestration: (a) the `a44f284` daily update carried the synthesis-layer edits from the prior HN-1 2026-08-20T18:00Z + web-search-1 2026-08-20 (skipped) + git-repo-1 2026-08-19T18:08Z runs; (b) the `bd30339` sources-sync re-applied the count-data wipe pattern on NocoDB / SeaFile / Wiki.js / RAGFlow for the **sixth** consecutive sources-sync (after 2026-08-15 `2507925` + 2026-08-16 `997b648` + 2026-08-17 `be49285` + 2026-08-18 `1fc73ae` + 2026-08-19 `dcb53a2`). **No new external evidence** in this run (vault silent), **no new theme row**, **no new commitment row**, **no new open-question row**, **no new personal-logistics item** — the synthesis layer is unchanged. Wiki edits this run: (a) `/sources/git-repo.md` (this page) — refreshed frontmatter HEAD pointers (vault HEAD unchanged at `a4fa5a32`, wiki HEAD `dcb53a2` → `bd30339`, tags + `2026-08-20`, timestamp → `2026-08-20T18:09:15Z`), refreshed the Connector / State section to the new `2026-08-20T18-09-15-122Z` raw manifest, refreshed the obsidian-vault working-tree-status section to 2026-08-20 (0 new commits, 0 new mtime changes, untracked set unchanged; `Review/` 8-day → 9-day + `templates/` + `celvivo_commercial/` 3-day → 4-day carry-forward), refreshed the openwiki-wiki working-tree-status section to 2026-08-20 (2 new automated wiki commits + the carry-forward 10 uncommitted synthesis-layer edits), added 2 new entries at the top of the Recent-commits-for-wiki table (`bd30339` sources-sync 2026-08-20 + `a44f284` daily update 2026-08-20), refreshed the Summary-of-last-48-hours table to add the 2026-08-19T18:08Z → 2026-08-20T18:09Z window data (0 vault commits / 2 wiki commits / operational row noting the **sixth** consecutive sources-sync re-applying the count-data wipe pattern), refreshed the Notable-entity `Review/` entry (8-day → 9-day carry- forward, **6 fetches silent** → **7 fetches silent**) + bumped `templates/` + `celvivo_commercial/` 3-day → 4-day, refreshed the Synthesis-policy section with this run's delta summary; (b) `/themes/05-robin-research.md` — vault-snapshot metadata refreshed (fetch timestamp → `2026-08-20T18:09:15Z`, raw-manifest path → the new `2026-08-20T18-09-15-122Z` manifest); the vault HEAD pointer stays `a4fa5a32` (unchanged across the 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 fetches); `Review/` 8-day → 9-day carry-forward; `Templates/` + `CelVivo-commercial/` 3-day → 4-day; (c) `/quickstart.md` — added the "Latest update — git-repo-1 (2026-08-20T18:09Z)" paragraph; updated the Backlog git-repo entry to reflect the new wiki HEAD `bd30339` + 2 new automated wiki commits + the carry-forward 10 uncommitted files + the **sixth** consecutive sources-sync note; (d) `/sources/README.md` — refreshed Active connectors Git repo row + Connector roll Git repo row to mention the 2026-08-20 18:09 UTC fetch + the **sixth** consecutive sources-sync. **No `/themes.md` row change, no `/commitments.md` row, no `/open-questions.md` row, no `/personal-logistics.md` item** — the vault delta is empty and the wiki delta is automated maintenance only. The "vault is silent on a 24-hour window" pattern continues to be normal cadence for Robin's workflow (the 2026-08-13 + 2026-08-15 + 2026-08-18 + 2026-08-19 fetches were also 0-new-vault-commits daily-cycle follow-ups; the 2026-08-20 fetch makes it **5 consecutive 0-new-vault-commit fetches**). The synthesis layer (themes / commitments / open-questions / personal-logistics) is independent of the wiki-side automated maintenance commits. - **Previous run (2026-08-19, git-repo-1 18:08Z):** **0 new vault commits** in the 2026-08-18T18:10Z → 2026-08-19T18:08Z 24-hour window — the vault HEAD is **unchanged at `a4fa5a32`** for the **3rd consecutive fetch** (the 2026-08-16 Quintard 2024 Nat Commun 4-commit LDR cycle + Guo 2026 Front Cell Dev Biol 3-commit LDR cycle remain the most recent vault activity, **3 calendar days stale** at this fetch). **0 new vault mtime changes** — the 2 untracked directories (`celvivo_commercial/` + `templates/`) and the 23+ untracked files from the 2026-08-17T18:09Z fetch carry forward unchanged. The `Review/zhou2023_computer_vision_microfluidics.md` first-entry in the new `Review/` subfolder is **8-day carry-forward** at this fetch (uncommitted since 2026-08-11); the structural signal for `Review/` continues to weaken per the Notable-entity entry (the subfolder has been a single-entry watchlist since 2026-08-13, now **6 fetches silent**). Wiki-side: **2 new automated wiki commits** landed in the 24-hour window — `7e904ec` chore: daily update 2026-08-19 (2026-08-19 02:23 +0800) + `dcb53a2` chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-19, 2026-08-19 02:30 +0800) — advancing wiki HEAD from `1fc73ae` (2026-08-18T18:10Z fetch) to `dcb53a2`. Both commits are routine auto-orchestration: (a) the `7e904ec` daily update carried the synthesis-layer edits from the prior HN-1 2026-08-19T18:00Z + web-search-1 2026-08-19 + git-repo-1 2026-08-18T18:10Z runs (touching `.last-update.json` + `quickstart.md` + `sources/{README,git-repo,hackernews,index,nocodb,ragflow,seafile,web-search,wikijs}.md` + `themes/05-robin-research.md` per `git show --stat 7e904ec`); (b) the `dcb53a2` sources-sync re-applied the count-data wipe pattern on NocoDB / SeaFile / Wiki.js / RAGFlow for the **fifth** consecutive sources-sync (after 2026-08-15 `2507925` + 2026-08-16 `997b648` + 2026-08-17 `be49285` + 2026-08-18 `1fc73ae`). **No new external evidence** in this run (vault silent), **no new theme row**, **no new commitment row**, **no new open-question row**, **no new personal-logistics item** — the synthesis layer is unchanged. Wiki edits this run: (a) `/sources/git-repo.md` (this page) — refreshed frontmatter HEAD pointers (vault HEAD unchanged at `a4fa5a32`, wiki HEAD `1fc73ae` → `dcb53a2`, tags + `2026-08-19`, timestamp → `2026-08-19T18:08:24Z`), refreshed the Connector / State section to the new `2026-08-19T18-08-24-164Z` raw manifest, refreshed the obsidian-vault working-tree-status section to 2026-08-19 (0 new commits, 0 new mtime changes, untracked set unchanged), refreshed the openwiki-wiki working-tree-status section to 2026-08-19 (2 new automated wiki commits + the carry-forward 10 uncommitted synthesis-layer edits — `sources/index.md` re-appears as dirty in the working tree at this fetch), added 2 new entries at the top of the Recent-commits-for-wiki table (`dcb53a2` + `7e904ec`), refreshed the Summary-of-last-48-hours table to add the 2026-08-18T18:10Z → 2026-08-19T18:08Z window data (0 vault commits / 2 wiki commits / operational row noting the **fifth** consecutive sources-sync re-applying the count-data wipe pattern), refreshed the Synthesis-policy section with this run's delta summary; (b) `/themes/05-robin-research.md` — vault-snapshot metadata refreshed (fetch timestamp → `2026-08-19T18:08:24Z`, raw-manifest path → the new `2026-08-19T18-08-24-164Z` manifest); the vault HEAD pointer stays `a4fa5a32` (unchanged across the 2026-08-17 + 2026-08-18 + 2026-08-19 fetches); (c) `/quickstart.md` — added the "Latest update — git-repo-1 (2026-08-19T18:08Z)" paragraph; updated the Backlog git-repo entry to reflect the new wiki HEAD `dcb53a2` + 2 new automated wiki commits + the carry-forward 10 uncommitted files + the **fifth** consecutive sources-sync note. **No `/themes.md` row change, no `/commitments.md` row, no `/open-questions.md` row, no `/personal-logistics.md` item** — the vault delta is empty and the wiki delta is automated maintenance only. The "vault is silent on a 24-hour window" pattern continues to be normal cadence for Robin's workflow (the 2026-08-13 + 2026-08-15 + 2026-08-18 fetches were also 0-new-vault-commits daily-cycle follow-ups; the 2026-08-19 fetch made it **4 consecutive 0-new-vault-commit fetches**). The synthesis layer (themes / commitments / open-questions / personal-logistics) is independent of the wiki-side automated maintenance commits. - **Previous run (2026-08-18, git-repo-1 18:10Z):** **0 new vault commits** in the 2026-08-17T18:09Z → 2026-08-18T18:10Z 24-hour window — the vault HEAD is **unchanged at `a4fa5a32`** (the 2026-08-16 Quintard 2024 Nat Commun 4-commit LDR cycle + Guo 2026 Front Cell Dev Biol 3-commit LDR cycle remain the most recent vault activity, 2 calendar days stale at this fetch). **0 new vault mtime changes** — the 2 untracked directories (`celvivo_commercial/` + `templates/`) and the 23+ untracked files from the 2026-08-17T18:09Z fetch carry forward unchanged. The `Review/zhou2023_computer_vision_microfluidics.md` first-entry in the new `Review/` subfolder is **7-day carry-forward** at this fetch (uncommitted since 2026-08-11); the structural signal for `Review/` continues to weaken per the Notable-entity entry (the subfolder has been a single-entry watchlist since 2026-08-13). Wiki-side: **2 new automated wiki commits** landed in the 24-hour window — `8127797` chore: daily update 2026-08-18 (2026-08-18 02:23 +0800) + `1fc73ae` chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-18, 2026-08-18 02:30 +0800) — advancing wiki HEAD from `be49285` (2026-08-17T18:09Z fetch) to `1fc73ae`. Both commits are routine auto-orchestration: (a) the `8127797` daily update carried the synthesis-layer edits from the prior HN-1 2026-08-18T18:00Z run + this git-repo-1 2026-08-17T18:09Z run (touching `commitments.md` + `index.md` + `quickstart.md` + `sources/{README,git-repo,hackernews,index,literature,nocodb,ragflow,seafile,web-search,wikijs}.md` + `themes/{01-organoid-equipment,05-robin-research}.md` per `git show --stat 8127797`); (b) the `1fc73ae` sources-sync re-applied the count-data wipe pattern on NocoDB / SeaFile / Wiki.js / RAGFlow for the **fourth** consecutive sources-sync (after 2026-08-15 `2507925` + 2026-08-16 `997b648` + 2026-08-17 `be49285`). **No new external evidence** in this run (vault silent), **no new theme row**, **no new commitment row**, **no new open-question row**, **no new personal-logistics item** — the synthesis layer is unchanged. Wiki edits this run: (a) `/sources/git-repo.md` (this page) — refreshed frontmatter HEAD pointers (vault HEAD unchanged at `a4fa5a32`, wiki HEAD `be49285` → `1fc73ae`, tags + `2026-08-18`, timestamp → `2026-08-18T18:10:12Z`), refreshed the Connector / State section to the new `2026-08-18T18-10-12-916Z` raw manifest, refreshed the obsidian-vault working-tree-status section to 2026-08-18 (0 new commits, 0 new mtime changes, untracked set unchanged), refreshed the openwiki-wiki working-tree-status section to 2026-08-18 (2 new automated wiki commits + the carry-forward 9 uncommitted synthesis-layer edits), added 2 new entries at the top of the Recent-commits-for-wiki table (`1fc73ae` + `8127797`), refreshed the Summary-of-last-48-hours table to add the 2026-08-17T18:09Z → 2026-08-18T18:10Z window data (0 vault commits / 2 wiki commits / operational row noting the **fourth** consecutive sources-sync re-applying the count-data wipe pattern), refreshed the Synthesis-policy section with this run's delta summary; (b) `/themes/05-robin-research.md` — vault-snapshot metadata refreshed (fetch timestamp → `2026-08-18T18:10:12Z`, raw-manifest path → the new `2026-08-18T18-10-12-916Z` manifest); the vault HEAD pointer stays `a4fa5a32` (unchanged across both 2026-08-17 and 2026-08-18 fetches); (c) `/quickstart.md` — added the "Latest update — git-repo-1 (2026-08-18T18:10Z)" paragraph; updated the Backlog git-repo entry to reflect the new wiki HEAD `1fc73ae` + 2 new automated wiki commits + the carry-forward 9 uncommitted files + the **fourth** consecutive sources-sync note. **No `/themes.md` row change, no `/commitments.md` row, no `/open-questions.md` row, no `/personal-logistics.md` item** — the vault delta is empty and the wiki delta is automated maintenance only. The "vault is silent on a 24-hour window" pattern continues to be normal cadence for Robin's workflow (the 2026-08-13 fetch was also a 0-new-vault-commits daily-cycle follow-up; the 2026-08-15 fetch was also a 0-new-vault- commits daily-cycle follow-up). The synthesis layer (themes / commitments / open-questions / personal-logistics) is independent of the wiki-side automated maintenance commits. - **Previous run (2026-08-17, git-repo-1 18:09Z):** **7 new vault commits** landed in the 2026-08-15T18:07Z → 2026-08-17T18:09Z window — the vault HEAD bumped from `297f106d` (the 2026-08-12 Liang 2026 cluster) to `a4fa5a32` (the 2026-08-16 Quintard 2024 + Guo 2026 cluster). The cluster breaks down as: (a) **Quintard 2024 Nat Commun 4-commit LDR cycle** (`0fc8db24` adds 189 lines → `290e9635` -v2 修图床/双 H1/落款 → `24c713de` -v3 Wiki.js 自带图床 6 张图 → `4073abf4` -v4 转发语标题/ 落款加粗/删 3Brain) on `obsidian-vault/Literature/Deep-Reads/Organoid/quintard_2024_vasorganoid_chip.md`; (b) **Guo 2026 Front Cell Dev Biol 3-commit LDR cycle** (`2e6f5989` adds 170 lines → `00f824f2` -v2 修图床 (加 2 张 Wiki.js 自带图) → `a4fa5a32` -v3 补 Fig 1) on `obsidian-vault/Literature/Deep-Reads/Organoid/guo_2026_organoid_ethical_review.md`. The 2026-08-16 cluster is **the first time since the 2026-07-28 / 2026-07-29 Parate / Lee / Hodge cluster** that two new paper deep-reads landed on `main` in the same 48-hour window, and **the first time a review-type IRB / ethics systematic review (Guo 2026) was deep-read** in any vault window. **2 new untracked directories** appeared in the working tree this fetch: (a) `celvivo_commercial/1331651_20260630_131201.pdf` (the 6-30 quote PDF migrated into a new folder); (b) `templates/类器官IRB申请清单.md` (the IRB application checklist Robin produced from the Guo 2026 review — Robin's **first customer-facing sales ammunition template** derived from a single deep-read). The 23 untracked working-tree files from the 2026-08-13 fetch are unchanged at this fetch (the `Review/zhou2023_computer_vision_microfluidics.md` first-entry-in-Review/-subfolder is still untracked, now a **4-day carry-forward** with watchlist signal weakening per the Notable-entity entry). Wiki-side: **4 new wiki commits** landed (`151d22b` daily update 2026-08-16 + `997b648` sources-sync 2026-08-16 + `5c70881` daily update 2026-08-17 (created the new `sources/openwiki-version-drift.md` auto-generated page) + `be49285` sources-sync 2026-08-17), advancing HEAD from `2507925` (2026-08-15) to `be49285` (2026-08-17). 9 dirty wiki files in the working tree (`.last-update.json` + `quickstart.md` + `sources/README.md` + `sources/hackernews.md` + `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/web-search.md` + `sources/wikijs.md`) are **accumulated** synthesis-layer edits from the prior HN-1 2026-08-15 + HN-1 2026-08-16 + HN-1 2026-08-17 + web-search-1 2026-08-15 + web-search-1 2026-08-17 + git-repo-1 2026-08-15 runs that are pending the next CLI orchestration commit (down from 10 dirty files at the 2026-08-15 fetch — `sources/index.md` got committed in the `151d22b` 2026-08-16 daily update). One **new wiki file** added in the window: `sources/openwiki-version-drift.md` (auto-generated OpenWiki version drift monitor; reports `v0.3.1` local → `v0.3.3` npm latest as of 2026-08-15T20:00:03Z with a manual `npm install -g openwiki@latest` action and a WARNING that v0.3.1 → v0.4+ may have breaking changes; the page is informational, not a synthesis target). **No `/commitments.md` row, no `/open-questions.md` row, no `/personal-logistics.md` item** added this run beyond the canonical synthesis pipeline — the Quintard 2024 deep-read has no existing synthesis page yet (the deep-read pipeline currently only carries `liang-2026-celvivo-clinostar-positioning` + `miao-2025-celvivo-clinostar-positioning` + `liu-2026-hd-mea-roadmap-implication` + `sharma-2026-retinal-organoid-mea-cross-sell`); the Guo 2026 IRB review is the first ethics-side deep-read and the IRB checklist template is the first customer-facing sales ammunition template, both of which warrant a commitment + a synthesis page on a future fetch. Wiki edits this run: (a) `/sources/git-repo.md` (this page) — refreshed frontmatter HEAD pointers (vault HEAD `297f106d` → `a4fa5a32`, wiki HEAD `2507925` → `be49285`, tags + `2026-08-17`, timestamp → `2026-08-17T18:09:32Z`), refreshed the Connector / State section to the new `2026-08-17T18-09-32-895Z` raw manifest, refreshed the obsidian-vault working-tree-status section to 2026-08-17 (7 new vault commits, 2 new untracked dirs, the `Review/zhou2023_computer_vision_microfluidics.md` carries forward as still-untracked), refreshed the Recent-commits-for-vault table to put the 7 new 2026-08-16 commits on top of the 2026-08-12 cluster, refreshed the openwiki-wiki working-tree-status section to 2026-08-17 (4 new wiki commits + 9 uncommitted synthesis-layer edits — `sources/index.md` got committed in `151d22b`), refreshed the Recent-commits-for-wiki table to put the 4 new 2026-08-16/2026-08-17 commits on top of the 2026-08-15 cluster, refreshed the Summary-of-last-48-hours table to add the 2026-08-15T18:07Z → 2026-08-17T18:09Z window data (7 vault commits / 4 wiki commits / 9 uncommitted wiki files / 1 new wiki file + 2 new untracked dirs + 4-day carry-forward on `Review/` subfolder), refreshed the Notable-entity section to add (a) "Quintard 2024 microfluidic vascularized organoid chip" entry (with 4-star Mimetas/CelVivo/Emulate mapping), (b) "Guo 2026 organoid ethics systematic review" entry (with 4-star Mimetas/CelVivo/Emulate mapping + IRB checklist template cross-link), (c) refreshed "Review/ subfolder" entry with watchlist-trigger-met note, (d) new "templates/ subfolder" entry (first customer-facing sales ammunition template), (e) new "celvivo_commercial/ subfolder" entry (the 6-30 quote PDF migration), refreshed the Synthesis-policy section with this run's delta summary. **No `/themes.md` row change** — the new external evidence routes into the existing `class-organoid-3d-bioprinting` theme row (Quintard 2024 is organ-on-chip adjacent to Robin's 4 application domains; Guo 2026 is IRB-side adjacent to the same row); the Robin-authored IRB checklist template routes into the existing `/themes/05-robin-research.md` "Sales ammunition pipeline" section rather than a new theme row. **No `/open-questions.md` row, no `/personal-logistics.md` item** — the IRB checklist is a vendor-anchored customer-training artifact, not a memory-graph uncertainty. (b) `/themes/05-robin-research.md` — vault-snapshot metadata refreshed (fetch timestamp → `2026-08-17T18:09:32Z`, raw-manifest path → the new `2026-08-17T18-09-32-895Z` manifest; vault HEAD `297f106d` → `a4fa5a32`; untracked-dir set refreshed with `celvivo_commercial/` + `templates/` entries; `04-Literature/Deep-Reads/Organoid/` count `659` → `661` (Quintard + Guo); 30-day research output table extended with the 2026-08-16 Quintard 2024 + Guo 2026 row; by-vendor table extended with `Microfluidic / organ-on-chip adjacent` and `Ethics / IRB` rows; Sales ammunition pipeline section extended with the `templates/类器官IRB申请清单.md` IRB checklist template). (c) `/themes/01-organoid-equipment.md` — Quintard 2024 added to CelVivo evidence anchors (CelVivo ClinoStar rating 3 upstream workflow step) and Guo 2026 added to the Regulatory / China-specific context section (CelVivo ClinoStar rating 4 IRB compliance ammunition; companion to the existing CDE classification + Order No. 818 items). (d) `/sources/literature.md` — Quintard 2024 + Guo 2026 added to the 30-day deep-read index. (e) `/sources/README.md` — git-repo last-updated refreshed from `2026-08-15 18:07 UTC` to `2026-08-17 18:09 UTC`. (f) `/quickstart.md` — added the "Latest update — git-repo-1 (2026-08-17T18:09Z)" paragraph. Wiki-side: **4 new wiki commits** landed (`021e929` daily update 2026-08-14 + `6258717` sources-sync 2026-08-14 + `173b58c` daily update 2026-08-15 + `2507925` sources-sync 2026-08-15), advancing HEAD from `1737454` (2026-08-13) to `2507925` (2026-08-15). **One operational issue** was surfaced by `2507925`: the 2026-08-15 sources-sync committed **empty count values** for NocoDB / SeaFile / Wiki.js / RAGFlow (NocoDB 6614 → 0, Wiki.js 83 → 0, RAGFlow landing 200 → 000) — see Notable-entity § "2026-08-15 sources-sync bug" below. 10 dirty wiki files in the working tree (`.last-update.json` + `quickstart.md` + `sources/README.md` + `sources/hackernews.md` + `sources/index.md` + `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/web-search.md` + `sources/wikijs.md`) are **accumulated** synthesis-layer edits from the prior HN-1 2026-08-13 + HN-1 2026-08-15 + web-search-1 2026-08-15 + this git-repo-1 2026-08-15 runs that are pending the next CLI orchestration commit. Wiki edits this run: (a) `/sources/git-repo.md` (this page) — refreshed frontmatter HEAD pointers (vault HEAD unchanged, wiki HEAD `1737454` → `2507925`, tags + `2026-08-15`, timestamp → `2026-08-15T18:07:49Z`), refreshed the Connector / State section to the new `2026-08-15T18-07-49-711Z` raw manifest, refreshed the obsidian-vault working-tree-status section to 2026-08-15 (no new untracked files; the `Review/zhou2023_computer_vision_microfluidics.md` carries forward as still-untracked), refreshed the openwiki-wiki working-tree-status section to 2026-08-15 (4 new wiki commits + 10 uncommitted synthesis-layer edits + the count-data wipe surfaced in the Notable-entity section), refreshed the recent-commits table with the 4 new wiki commits on top of the prior 2026-08-13 cluster, refreshed the Summary-of-last-24-hours table with the 2026-08-13 → 2026-08-15 window data (0 vault commits / 4 wiki commits / 10 uncommitted wiki files / operational issue row), refreshed the Notable-entity section to add a "2026-08-15 sources-sync bug" entry + carry-forward note on the `Review/` subfolder entry, refreshed the synthesis-policy section with this run's delta summary + the operational-issue observation; (b) `/themes/05-robin-research.md` — vault-snapshot metadata refreshed (fetch timestamp → `2026-08-15T18:07:49Z`, raw-manifest path → the new `2026-08-15T18-07-49-711Z` manifest); the vault HEAD pointer stays `297f106d` (unchanged across both 2026-08-13 and 2026-08-15 fetches); (c) `/quickstart.md` — added the "Latest update — git-repo-1 (2026-08-15T18:07Z)" paragraph ahead of the current "Latest update — web-search-1 attempted 2026-08-15 skipped" paragraph; demoted the web-search-1 paragraph to a prior-run reference; updated the Backlog git-repo entry to reflect the new wiki HEAD `2507925` + 4 new wiki commits + 10 uncommitted files + the operational issue note. **No `/commitments.md` row, no `/open-questions.md` row, no `/personal-logistics.md` item, no `/themes.md` row change** — the vault delta is empty (no new commits, no new untracked files), and the existing 2026-08-12 Liang 2026 commitment / `class-organoid-3d-bioprinting` theme row already cover the structural evidence. - **Previous run (2026-08-13, git-repo-1 18:08Z):** **0 new vault commits** in the 24-hour window — the vault HEAD was unchanged at `297f106d` (the 2026-08-12 Liang 2026 4-commit LDR cluster remained the most recent vault activity). The only vault-side delta was **1 new untracked file**: `04-Literature/Deep-Reads/Review/zhou2023_computer_vision_microfluidics.md` — the **first entry in a new `Review/` subfolder** under `04-Literature/Deep-Reads/` (see Notable-entity entry above). 1 noise file (`__pycache__/...pyc`) was ignored. Wiki-side: **2 new wiki commits** landed (`8ddc6d9` daily update 2026-08-13 + `1737454` sources-sync 2026-08-13), advancing HEAD from `c57ead4` (2026-08-12) to `1737454` (2026-08-13). 8 dirty wiki files in the working tree were synthesis-layer edits from the prior HN-1 2026-08-13 run that landed after `1737454` committed and were pending the next CLI orchestration commit. - **Previous run (2026-08-12, git-repo-1 18:08Z):** 4 new vault commits on the **same single Liang 2026 Sci Rep liver organoid paper** walked through Robin's standard 3-stage LDR cycle (`e542c977` adds file → `8699a154` page 946 9 项 SOP 重写版 → `aacba7aa` + `297f106d` page 934 修齐 micro-revisions) — this was the **net-new external evidence** for that run. Wiki edits at that time are described in the synthesis-policy paragraph above; the canonical synthesis continues to live at `/themes/01-organoid-equipment.md`, `/themes/05-robin-research.md`, and `/commitments.md` `liang-2026-celvivo-clinostar-positioning`. - The vault is a knowledge base, not a live signal stream; durable per-document synthesis (paper deep reads, sales scripts, customer files) requires reading individual files, which is delegated to the Hermes skill and RAGFlow. - Future runs should keep this page structural. Promote a row to a canonical theme only when the connector observes a recurring workflow (e.g. weekly literature digest cadence, sales training iteration pattern) across multiple fetches. - **Process signal worth watching (2026-08-13):** (a) **New `Review/` subfolder signal** — Robin added a 20th subfolder under `04-Literature/Deep-Reads/` dedicated to review-type papers, with `zhou2023_computer_vision_microfluidics.md` as the first entry. If the subfolder accumulates ≥3 entries, this signals a formal review-paper stream is being built separately from the original-research stream; if it stays at 1 entry, it's a one-off. (b) **Liang 2026's MOC linkage confirms the MOC pattern is in active use** — the paper's `related:` field already names `[[MOC-类器官与3D培养]]` (the first MOC, created 2026-08-10) on the day of publication, not a future-state plan. Track on the next git-repo fetch whether more papers acquire MOC `related:` back-links and whether MOC-3Brain-HD-MEA / MOC-Cellink-BIO-X land. (c) **Page 934 修齐 micro-revisions now appear on every new LDR cycle** — `297f106d` is the second paper (after `381fcbaa` OVB-organoids 2026-08-11) where Robin applied the H1 去括号 / 元数据 bold / 📄PDF 文件名 alignment. The pattern appears to be the new standard end-state. (d) **Phase A frontmatter batch rollout** is still paused (only 6 of ~1,204 deep-reads received the 6-field frontmatter); no progress this run. ## Next update Run `openwiki_ingest_connector connectorId=git-repo` (or `openwiki personal --update`) to refresh. Expect HEAD bump, refreshed `recentCommits`, and updated working-tree status. rking-tree status.