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lit: PMID 42041571 v4 - 按 literature-deep-read-research 9 项强制格式

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2026-08-11 12:35:37 +08:00
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@@ -181,6 +181,6 @@ The `Robin_Picked_Papers` table is **new as of today** — created per Robin's 2
- **Wiki.js**: [ID 1708](http://10.10.10.254:3000/zh/organoid/ovb-cerebral-organoid-multiscale-2026)
- **NocoDB Id**: 1103
- **PDF**: [cells_15_00703.pdf](https://fb.biokingdom.top/f/582d1f055f6e4365a924/?raw=1) + 10 张真实配图(xref extract)
- **Key finding**: 首次标准化 OVB-类器官(视泡-大脑)vs 大脑类器官多尺度对比;Day 30 FOXG1+VSX2 共表达;TEM 突触+髓鞘;1,625/2,924 DEGs
- **Key finding**: Cells 2026 重磅 - OVB-organoids vs Cerebral 多尺度对比(中国军事医学科学院); Day 30 FOXG1+53.86% + VSX2+4.18%; TEM 突触+髓鞘; 1625 上调 + 2924 下调 DEGs; CHRNB2 6.5 倍差异; KEGG 富集到神经突触功能 vs 免疫炎症代谢
- **Business relevance**: OVB-organoids + 3Brain MEA = 眼-脑协同发育研究完整解决方案
- **Tags**: OVB-organoids, cerebral-organoids, brain-development, retinal-organoid, FOXG1, VSX2