diff --git a/sources/literature.md b/sources/literature.md index 044d9e8..6738086 100644 --- a/sources/literature.md +++ b/sources/literature.md @@ -184,3 +184,16 @@ The `Robin_Picked_Papers` table is **new as of today** — created per Robin's 2 - **Key finding**: Cells 2026 重磅 - OVB-organoids vs Cerebral 多尺度对比(中国军事医学科学院); Day 30 FOXG1+53.86% + VSX2+4.18%; TEM 突触+髓鞘; 1625 上调 + 2924 下调 DEGs; CHRNB2 6.5 倍差异; KEGG 富集到神经突触功能 vs 免疫炎症代谢 - **Business relevance**: OVB-organoids + 3Brain MEA = 眼-脑协同发育研究完整解决方案 - **Tags**: OVB-organoids, cerebral-organoids, brain-development, retinal-organoid, FOXG1, VSX2 + +### 2026-08-11 - PMID 41909700 + +- **Title**: Organoid-microglia system for modeling the immune microenvironment of the brain and retina +- **Authors**: Yu J, Tang B, Gu Z, Wang G, Liu A +- **Journal**: Frontiers in Immunology 2026, 17:1747589 +- **DOI**: 10.3389/fimmu.2026.1747589 +- **Wiki.js**: [ID 1709](http://10.10.10.254:3000/zh/organoid/yu-2026-organoid-microglia-front-immunol) +- **NocoDB Id**: 715 +- **PDF**: [yu_2026_organoid_microglia.pdf](https://fb.biokingdom.top/f/4537d08bf4d14c6db0bc/?dl=1) + 4 张真图 +- **Key finding**: 类器官-小胶质细胞共培养 3 大策略 + 6 大应用 (AD/ASD/视网膜/药筛/CRISPR/OoC); 神经-免疫体外模型空白填补 +- **Business relevance**: 3Brain MEA + CelVivo ClinoStar + Femtobiomed CellShot + Cellink BIO X 4 大产品线全交叉 +- **Tags**: 类器官, 小胶质细胞, 神经免疫, 脑-视网膜, 共培养