chore: daily update 2026-08-26

.last-update.json

@@ -1,7 +1,7 @@
 {
-  "updatedAt": "2026-08-24T18:23:53.059Z",
+  "updatedAt": "2026-08-25T18:25:45.423Z",
   "command": "update",
   "model": "MiniMax-M3",
-  "status": "complete",
+  "status": "interrupted",
   "language": "en"
 }

commitments.md

@@ -2,7 +2,8 @@
 type: "Reference"
 title: "Commitments"
 description: "Active work tasks, follow-ups, approvals, and scheduled items extracted from sources (web-search, git-repo, literature flywheel-sync, etc.). Personal errands live in /personal-logistics.md instead."
-tags: [commitments, work, follow-ups, distributors-2026-08-07-refresh, dong-huiqun-ji-nan-chengquan-link, liang-2026-celvivo-clinostar-positioning, guo-2026-organoid-irb-checklist-rollout]
+tags: [commitments, work, follow-ups, distributors-2026-08-07-refresh, dong-huiqun-ji-nan-chengquan-link, liang-2026-celvivo-clinostar-positioning, guo-2026-organoid-irb-checklist-rollout, celvivo-app-note-2026-clinostar-vs-orbital-shaker-positioning, aiello-2025-rc-cfd-clinostar-positioning, kim-2025-egain-3d-mea-vs-3brain-positioning, ajongbolo-2025-brain-organoid-review-cluster, tian-2025-epicardium-mtor-cardiac-expansion, tevonian-2026-vascularized-liver-mps-positioning, yang-2026-cardiac-organoid-review-positioning, shen-2026-vascularized-organoid-chinese-review, zhai-2026-skin-organoid-pemphigus-positioning, 2026-08-25]
+timestamp: 2026-08-25T18:13:00Z
 ---
 
 # Commitments
@@ -158,6 +159,34 @@ Concrete work tasks, follow-ups, approvals, and scheduled items extracted from G
 - Status: open
 - Notes: **First cardiac-epicardium paper in Robin's deep-read set** — Tian paper establishes **Torin1 (dual mTORC1/2 inhibitor, 200 nM) drives hiPSC epicardium maturation** with mature markers (TJP1/WT1/TBX18/ALDH1A2/CDH18) up + EMT markers down + proliferation markers down + fatty-acid metabolism maturation; 379 DEGs; adult-like profile vs GSE84085; YBX3 + MAFF identified as Torin1-specific TFs; **paracrine TNNI3 upregulation in hiPSC ventricular cardiomyocyte EBs co-cultured for 10 days** (epicardium-to-cardiomyocyte maturation cross-talk). **Application domain**: cardiac organoid regeneration — fits the broad cardiac application-domain bucket that Robin's wiki scope covers. **No vendor callouts in the deep-read** (no CelVivo / 3Brain / Cellink / FemtoBiomed product rating) but the paracrine cross-talk finding is a candidate for cross-vendor positioning if Robin pitches cardiac-regeneration programs to pharma R&D or CDMO accounts. The 15,578-byte size is the **largest** of the 5 new LDR files — reflects Robin's deep-dive on the mTOR pathway mechanism. Follow-ups: (a) add a wiki-side deep-read synthesis page at `/sources/literature-tian-2025-nat-commun-epicardium-mtor-deepread.md`; (b) verify whether any active Chinese pharma R&D / CDMO / regenerative-medicine account maps to the cardiac-epicardium lane (the active CRM profile set is mostly CelVivo / 3Brain neural-organoid focused — no cardiac-epicardium customer dossier surfaced yet); (c) consider whether Robin should fold cardiac into the existing `/themes/01-organoid-equipment.md` theme or open a new `theme-cardiac-regeneration.md` if cardiac papers recur.
 
+### tevonian-2026-vascularized-liver-mps-positioning: Tevonian 2026 Nat Commun vascularized liver MPS vendor-mapping + 中国药企 hepatic-IR 药筛 positioning
+- Owner: me
+- Source: git-repo-1 2026-08-25 — vault commit `089177a7` (Tevonian et al. 2026 Nat Commun vascularized liver microphysiological system, PMID 41634021, DOI 10.1038/s41467-025-68031-6; vault path `obsidian-vault/04-Literature/Deep-Reads/Vascularized-Organoids/Tevonian_2026_Nat_Commun_Vascularized_Liver_MPS.md`, **first file in new `Vascularized-Organoids/` subfolder**)
+- Due: unscheduled
+- Status: open
+- Notes: **First vascularized liver MPS paper** in Robin's deep-read set; **5-vendor product mapping retrofit applied** via the `9aa2af4c` post-publish retrofit commit (CelVivo ClinoStar / ClinoReactor + Cellink BIO X + Mimetas OrganoPlate + 3Brain HD-MEA + FemtoBiomed CellShot). Mimetas OrganoPlate is the canonical microphysiological system for the multi-channel vascularized liver architecture (PDMS + fibrin + primary hepatocytes + HUVEC) + CelVivo ClinoReactor for upstream hepatocyte maturation (Hep-Orgs source) + Cellink BIO X for the decellularized liver scaffold matrix. **Application domain**: vascularized liver MASLD/NASH 体外建模 + 个性化药筛 + 血管化类器官平台. Companion to the existing **Liang 2026** liver organoid entry (ClinoStar ⭐⭐⭐⭐ for P1-P10 long-term maturation + ClinoReactor ⭐⭐⭐⭐ for 3-track HEP/CHO/HSC perfusion) — Tevonian 血管化 dimension extends the existing Liver/ subfolder's fibrotic disease modeling story. Follow-ups: (a) add a wiki-side deep-read synthesis page at `/sources/literature-tevonian-2026-nat-commun-vascularized-liver-mps-deepread.md`; (b) cross-link Tevonian with Shen 2026 in the new Vascularized-Organoids/ subfolder to anchor a vascularized-organoid review-paper cluster; (c) verify whether the active MASLD/NASH hepatic-IR account dossier (if any in the CRM) maps to Mimetas OrganoPlate CelVivo ClinoReactor + Cellink BIO X as a triple-vendor solution.
+
+### yang-2026-cardiac-organoid-review-positioning: Yang 2026 Stem Cell Res Ther cardiac organoid review vendor-mapping + 心脏药物毒性测试 positioning
+- Owner: me
+- Source: git-repo-1 2026-08-25 — vault commit `583859a8` (Yang L et al. 2026 Stem Cell Res Ther cardiac organoid review, PMID 41963991, DOI 10.1186/s13287-026-04996-5; vault path `obsidian-vault/04-Literature/Deep-Reads/Cardiac-Organoids/Yang_2026_Stem_Cell_Res_Ther_Cardiac_Organoid_Review.md`, **first file in new `Cardiac-Organoids/` subfolder**)
+- Due: unscheduled
+- Status: open
+- Notes: **First comprehensive cardiac organoid review** in Robin's deep-read set; **5-vendor product mapping retrofit applied** via the `9aa2af4c` post-publish retrofit commit (same 5-vendor mapping as Tevonian). Companion to **Tian 2025 Nat Commun** (the cardiac epicardium mTOR paper from the 2026-08-23 burst) which established the actual mechanistic depth — Yang 2026 is the canonical review that contextualizes Tian alongside the prior cardiac organoid literature (hPSC cardiac organoid generation methods, maturation protocols, disease modeling applications, regenerative medicine routes). Covers FGF/PI3K/Wnt/BMP/Activin/RA 五大信号通路 + 三种 3D 培养策略. **Application domain**: cardiac organoid — Robin expands from the prior 2-paper Cardiac/ subfolder to a dedicated Cardiac-Organoids/ subfolder; first time Robin has opened a new subfolder explicitly for an application-domain cluster. **Robin 业务对接**: 心脏药物毒性测试 + hiPSC 衍生心脏类器官服务 + 心血管疾病建模. Follow-ups: (a) add a wiki-side deep-read synthesis page at `/sources/literature-yang-2026-stem-cell-res-ther-cardiac-organoid-review-deepread.md`; (b) pair Tian + Yang as a paired mechanistic + review cluster on `/themes/05-robin-research.md`; (c) verify whether any active Chinese pharma R&D cardiac-toxicology account maps to CelVivo + 3Brain as a paired vendor solution for hiPSC-derived cardiac organoid electrophysiology.
+
+### shen-2026-vascularized-organoid-chinese-review: Shen 2026 Chin Med J vascularized organoid systematic review for Chinese-hospital IRB positioning
+- Owner: me
+- Source: git-repo-1 2026-08-25 — vault commit `5907cdfc` (Shen Y et al. Chin Med J 2026 vascularized organoids systematic review, PMID 42268296, DOI 10.1097/CM9.0000000000004136; vault path `obsidian-vault/04-Literature/Deep-Reads/Vascularized-Organoids/Shen_2026_Chin_Med_J_Vascularized_Organoids_Review.md`, Chinese-language peer-reviewed systematic review from 华西医院, second file in new Vascularized-Organoids/ subfolder)
+- Due: unscheduled
+- Status: open
+- Notes: **Chinese-language peer-reviewed vascularized organoid systematic review** — establishes credential Chinese-hospital-academic source for Robin's active Chinese pharma R&D / CDMO customer base. Structures vascularized organoid 4 大策略 (共培养 + 转录因子诱导 + 微流控 + 生物材料支架) + 12 维对比 + 三大未来方向. **Vendor anchor mapping**: TBD — not retrofitted by `9aa2af4c` (only Tevonian + Yang got the 5-vendor retrofit). **Application domain**: vascularized organoid — adds a 2-paper cluster to the new Vascularized-Organoids/ subfolder. The Shen 2026 review is the **review-paper anchor** and Tevonian 2026 is the **research-paper anchor**. **Robin 业务对接**: 血管化类器官服务 + 多层血管网络平台 + 个性化精准医疗. Follow-ups: (a) add a wiki-side deep-read synthesis page at `/sources/literature-shen-2026-cmj-vascularized-organoids-review-deepread.md`; (b) cross-link with Tevonian 2026 to anchor a vascularized-organoid review-paper cluster; (c) verify whether the Chinese-language source yields any CelVivo-specific IRB or vascularization positioning material for Chinese-hospital customer conversations.
+
+### zhai-2026-skin-organoid-pemphigus-positioning: Zhai 2026 Sci Adv 3D skin pemphigus autoimmune dermatology positioning
+- Owner: me
+- Source: git-repo-1 2026-08-25 — vault commit `9d4767c7` (Zhai T et al. Sci Adv 2026 3D skin pemphigus, PMID 41512055, DOI 10.1126/sciadv.adz5003; vault path `obsidian-vault/04-Literature/Deep-Reads/Skin-Organoids/Zhai_2026_Sci_Adv_3D_Skin_Pemphigus.md`, **first file in new `Skin-Organoids/` subfolder**, **net-new application domain** — autoimmune dermatology + 3D skin)
+- Due: unscheduled
+- Status: open
+- Notes: **First 3D-skin organoid disease-modeling paper** in Robin's deep-read set; **net-new application domain** (autoimmune dermatology + 3D skin) that Robin's existing ~22 deep-read subfolders do not cover. Uses **3D 打印 + 自组织多层血管化皮肤模型** to model 天疱疮 (pemphigus) autoimmune disease + EGFR 靶向治疗 + ML 辅助药筛. **Vendor anchor mapping**: TBD — Zhai paper does NOT have the `9aa2af4c` retrofit 5-vendor mapping (only Tevonian + Yang got the retrofit). Skin organoid is a candidate workflow for **CelVivo ClinoReactor** (long-term 3D skin culture — similar to the existing liver, brain, lung, retinal organoid applications) but the Sci Adv paper's specific ClinoReactor / ClinoStar callouts are not in the manifest entry. **Application domain**: 3D skin organoid + autoimmune dermatology (pemphigus) — distinct from the existing Cancer / Brain / Liver / Vascularized-Organoids / Cardiac-Organoids / Kidney / Retinal / Brain-Tumor application-domain subfolders. **Robin 业务对接**: 皮肤自身免疫病药筛 + 3D 打印客户 + 精准医疗应用. Follow-ups: (a) add a wiki-side deep-read synthesis page at `/sources/literature-zhai-2026-sciadv-3d-skin-pemphigus-deepread.md`; (b) verify whether the Skin-Organoids subfolder accumulates ≥3 entries to confirm a recurring application-domain pattern; (c) check whether the Zhai paper yields Chinese cosmetic / dermatology pharma R&D positioning material that the active CRM portfolio could absorb.
+
 <!--
 Structure for new entries:
 

index.md

@@ -8,7 +8,7 @@ okf_version: "0.1"
 - [2026-07-16 工具链打通战报](memory-2026-07-16-tools-final.md) - After-action report on Robin's 2026-07-16 end-to-end toolchain integration: OpenWiki + Gitea + NocoDB + RAGFlow + Wiki.js + MiniMax code all wired together and working in production. Snapshot of the pre-flywheel-sync state — pre-dates the 2026-07-26 HN + Tavily launches and the 2026-07-29 Tavily cluster / 2026-08-08 literature flywheel-sync milestones.
 - [Open Questions](open-questions.md) - Active, Answered, and Stale unresolved questions about Robin's memory, recurring routines, people, projects, and wiki quality. Source-document TODOs and product questions live on their source pages instead.
 - [Personal Logistics](personal-logistics.md) - Personal errands, appointments, pickups, travel, household/life-admin deadlines, and other non-work logistics. Work commitments live in /commitments.md.
-- [Robin's Local Knowledge Base](quickstart.md) - OpenWiki entrypoint and orientation — Robin's personal knowledge base with 5 synthesis themes (organoid equipment, bioprinting, AI agents, local LLM, personal research), navigation map, current connector status, and backlog. The 2026-08-24 18:05 UTC fetch surfaced the largest single-day LDR burst since 2026-07-29 — 5 papers committed to the Obsidian vault main + new pipeline-workspace directory `deepread_40240593/`.
+- [Robin's Local Knowledge Base](quickstart.md) - OpenWiki entrypoint and orientation — Robin's personal knowledge base with 5 synthesis themes (organoid equipment, bioprinting, AI agents, local LLM, personal research), navigation map, current connector status, and backlog. The 2026-08-25 18:13 UTC git-repo-1 fetch observed the **SECOND consecutive single-day 5-paper LDR burst** at vault HEAD (`fb017e4f` → `9d4767c7`) — combined with the 2026-08-23/24 burst, **10 LDR files in 48 hours** is the largest sustained 2-day research output in Robin's vault activity log; **3 new `04-Literature/Deep-Reads/` subfolders** created in a single day (`Vascularized-Organoids/` + `Cardiac-Organoids/` + `Skin-Organoids/`); the first post-publish vendor-mapping retrofit commit (`9aa2af4c`) added a 5-vendor product mapping table to Tevonian + Yang — the first post-publish vendor-mapping step in Robin's LDR SOP. Wiki HEAD bumped `127c2dc` → `1003b92` via 2 automated wiki commits (`3255613` 17-file daily update + `1003b92` sources-sync 2026-08-25 — the eleventh consecutive sources-sync).
 - [OpenWiki 现状 + 操作手册 (2026-07-27)](README-ACTIVATION.md) - Activation status + operations manual for Robin's local OpenWiki knowledge base as of 2026-07-27. Documents 4 active connectors (HN + git-repo + Tavily + RAGFlow) and the per-source sync scripts (HN top+best feeds, Tavily web-search with TAVILY_API_KEY, git-repo Obsidian vault at /home/ldw/workspace, RAGFlow full-text retrieval at 10.10.10.254:9980). Captures the on-disk Gitea commit + push pattern.
 - [Themes](themes.md) - Recurring topics, signals, and trends observed across Robin's sources. Index of theme rows with confidence labels and source citations; details live on the linked source and synthesis pages.
 

quickstart.md

@@ -1,9 +1,9 @@
 ---
 type: "Reference"
 title: "Robin's Local Knowledge Base"
-description: "OpenWiki entrypoint and orientation — Robin's personal knowledge base with 5 synthesis themes (organoid equipment, bioprinting, AI agents, local LLM, personal research), navigation map, current connector status, and backlog. The 2026-08-24 18:05 UTC fetch surfaced the largest single-day LDR burst since 2026-07-29 — 5 papers committed to the Obsidian vault main + new pipeline-workspace directory `deepread_40240593/`."
-tags: [quickstart, navigation, openwiki, status, 2026-08-24, 2026-08-23, 2026-08-22]
-timestamp: 2026-08-24T18:05:00Z
+description: "OpenWiki entrypoint and orientation — Robin's personal knowledge base with 5 synthesis themes (organoid equipment, bioprinting, AI agents, local LLM, personal research), navigation map, current connector status, and backlog. The 2026-08-25 18:13 UTC git-repo-1 fetch observed the **SECOND consecutive single-day 5-paper LDR burst** at vault HEAD (`fb017e4f` → `9d4767c7`) — combined with the 2026-08-23/24 burst, **10 LDR files in 48 hours** is the largest sustained 2-day research output in Robin's vault activity log; **3 new `04-Literature/Deep-Reads/` subfolders** created in a single day (`Vascularized-Organoids/` + `Cardiac-Organoids/` + `Skin-Organoids/`); the first post-publish vendor-mapping retrofit commit (`9aa2af4c`) added a 5-vendor product mapping table to Tevonian + Yang — the first post-publish vendor-mapping step in Robin's LDR SOP. Wiki HEAD bumped `127c2dc` → `1003b92` via 2 automated wiki commits (`3255613` 17-file daily update + `1003b92` sources-sync 2026-08-25 — the eleventh consecutive sources-sync)."
+tags: [quickstart, navigation, openwiki, status, 2026-08-25, 2026-08-24, 2026-08-23, 2026-08-22]
+timestamp: 2026-08-25T18:13:00Z
 ---
 
 # Robin's Local Knowledge Base
@@ -34,9 +34,15 @@ timestamp: 2026-08-24T18:05:00Z
 
 ## Current status
 
-- **Wiki state:** initialized — Hacker News, the local Obsidian vault, and Tavily web search are active and feeding `/sources/hackernews.md`, `/sources/git-repo.md`, `/sources/web-search.md`, and `/themes.md`. All 5 synthesis themes (`/themes/01-organoid-equipment.md`, `/themes/02-bioprinting.md`, `/themes/03-ai-agents.md`, `/themes/04-local-llm.md`, `/themes/05-robin-research.md`) are now generated; the 2026-08-17 daily update created `/sources/openwiki-version-drift.md` (auto-generated OpenWiki version-drift monitor); the 2026-08-24 daily update committed the synthesis-layer edits from the prior HN-1 2026-08-23T18:00Z + web-search-1 2026-08-23 (skipped) + git-repo-1 2026-08-23T18:11Z runs; the wiki HEAD bumped to `127c2dc` (sources-sync 2026-08-24, the **tenth** consecutive sources-sync re-applying the `2507925` 2026-08-15 count-data wipe pattern after `997b648` 2026-08-16 + `be49285` 2026-08-17 + `1fc73ae` 2026-08-18 + `dcb53a2` 2026-08-19 + `bd30339` 2026-08-20 + `f6c2576` 2026-08-21 + `43d4548` 2026-08-22 + `8f8f767` 2026-08-23 + now `127c2dc` 2026-08-24). The 8 uncommitted synthesis-layer edits re-appear in the working tree because the very next synthesis edits from this git-repo-1 2026-08-24T18:05Z run re-touch the same files. **2026-08-24 18:05 UTC update**: git-repo-1 (Obsidian vault + OpenWiki wiki) ran; **vault HEAD bumped** `a4fa5a32` → `fb017e4f` via **5 new vault commits** (the largest single-day LDR burst since 2026-07-29: Ajongbolo 2025 Cells brain organoid review + Kim 2025 Nat Commun EGaIn 3D MEA + Tian 2025 Nat Commun hiPSC epicardium mTOR + Aiello & Bagni 2025 biorxiv Rotating Chamber brain organoid CFD + CelVivo App Note 2026 shear stress ClinoStar vs orbital shaker — all 5 landed at `04-Literature/Deep-Reads/` root, non-standard pattern); wiki HEAD bumped `a9568d8` → `127c2dc` via 2 automated wiki commits (`9cc5e63` daily update 2026-08-24 + `127c2dc` sources-sync 2026-08-24 — the **tenth** consecutive sources-sync); 5 new commitments added to `/commitments.md` (one per new LDR paper); 5 new rows added to `/sources/literature.md` "Last 30 days of deep reads" table; `/themes.md` `class-organoid-3d-bioprinting` evidence footprint strengthened (3 of 5 papers vendor-aligned to CelVivo + 3Brain) but no new theme row at this fetch.
+- **Wiki state:** initialized — Hacker News, the local Obsidian vault, and Tavily web search are active and feeding `/sources/hackernews.md`, `/sources/git-repo.md`, `/sources/web-search.md`, and `/themes.md`. All 5 synthesis themes (`/themes/01-organoid-equipment.md`, `/themes/02-bioprinting.md`, `/themes/03-ai-agents.md`, `/themes/04-local-llm.md`, `/themes/05-robin-research.md`) are now generated; the 2026-08-17 daily update created `/sources/openwiki-version-drift.md` (auto-generated OpenWiki version-drift monitor); the 2026-08-25 daily update committed 17 files from the prior dirty set (the largest single daily update in Robin's OpenWiki activity log), including the synthesis-layer edits from the prior HN-1 2026-08-25T18:00Z + web-search-1 2026-08-25 (skipped) + git-repo-1 2026-08-24T18:05Z runs; the wiki HEAD bumped to `1003b92` (sources-sync 2026-08-25, the **eleventh** consecutive sources-sync re-applying the `2507925` 2026-08-15 count-data wipe pattern after `997b648` 2026-08-16 + `be49285` 2026-08-17 + `1fc73ae` 2026-08-18 + `dcb53a2` 2026-08-19 + `bd30339` 2026-08-20 + `f6c2576` 2026-08-21 + `43d4548` 2026-08-22 + `8f8f767` 2026-08-23 + `127c2dc` 2026-08-24 + now `1003b92` 2026-08-25). The 11 uncommitted synthesis-layer edits re-appear in the working tree because the very next synthesis edits from this git-repo-1 2026-08-25T18:13Z run re-touch the same files. **2026-08-25 18:13 UTC update**: git-repo-1 (Obsidian vault + OpenWiki wiki) ran; **vault HEAD bumped** `fb017e4f` → `9d4767c7` via **5 new vault commits** (the **SECOND consecutive single-day 5-paper LDR burst** — combined with the 2026-08-23/24 5-paper burst, **10 LDR files in 48 hours** = the largest sustained 2-day research output in Robin's vault activity log: Tevonian 2026 Nat Commun vascularized liver MPS + Yang 2026 Stem Cell Res Ther cardiac organoid review + post-publish vendor-mapping retrofit commit + Shen 2026 Chin Med J vascularized organoids review + Zhai 2026 Sci Adv 3D skin pemphigus — **3 NEW `04-Literature/Deep-Reads/` subfolders** created in a single day: `Vascularized-Organoids/` + `Cardiac-Organoids/` + `Skin-Organoids/`, the first new subfolders since the 2026-08-13 `Review/` subfolder); wiki HEAD bumped `127c2dc` → `1003b92` via 2 automated wiki commits (`3255613` daily update 2026-08-25 committed 17 files — the largest single daily update in the wiki's history + `1003b92` sources-sync 2026-08-25 — the **eleventh** consecutive sources-sync); 4 new commitments added to `/commitments.md` (one per new LDR paper); 4 new rows added to `/sources/literature.md` "Last 30 days of deep reads" table; `/themes.md` `class-organoid-3d-bioprinting` evidence footprint strengthened (10 papers in 48 hours, 3 new application-domain subfolders, the `9aa2af4c` retrofit introduced the first post-publish vendor-mapping step in Robin's LDR SOP) but no new theme row at this fetch.
 - **Connectors:** Hacker News, git-repo, and web search active. The 2026-08-08, 2026-08-10, 2026-08-12, 2026-08-15, 2026-08-17, 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, and 2026-08-23 web-search update attempts were skipped because the connector is not enabled and `TAVILY_API_KEY` is empty; the latest successful Tavily pull remains 2026-08-03 18:08 UTC. Gmail, Slack, Notion, and X are not yet configured — see "Adding sources" below.
 
+**Latest update — web-search-1 attempted 2026-08-25 skipped.** One source-specific update run for `web-search-1` (Web Search / Tavily) per the source-specific instruction "Track CelVivo / 3Brain / Cellink / organoid news from web (NOTE: needs TAVILY_API_KEY, currently empty)". The deterministic pull was **skipped**: `web-search-1` is not enabled in the runtime registry and `TAVILY_API_KEY` is empty, so no Tavily request was made and no raw data files were written. The nightly searxng-fallback slot `~/.openwiki/connectors/web-search/raw/2026-08-24T18-35-03-searxng-fallback/` is also empty (confirmed empty on disk — no files in the directory) — no web-search evidence of any kind landed in the 24-hour window. This is the **thirteenth consecutive skip** on the same code path (after 2026-08-08 + 2026-08-10 + 2026-08-12 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24); the latest successful Tavily pull remains 2026-08-03 18:08 UTC. No new CelVivo / 3Brain / Cellink / organoid findings were available for synthesis; no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md` from this source attempt. Discord between on-disk `~/.openwiki/connectors/web-search/config.json` (which shows `enabled: true` + 6 Chinese queries) and the runtime registry (still reports the connector as disabled) is the same operational issue noted on the 2026-08-08 / 2026-08-10 / 2026-08-12 + 2026-08-15 / 2026-08-17 / 2026-08-18 + 2026-08-19 / 2026-08-20 / 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 runs — recorded for traceability only, not a wiki-synthesis concern. Wiki edits this run: (a) `/sources/web-search.md` — added a "2026-08-25 attempted update — skipped" section ahead of the 2026-08-24 entry, following the established 5-field structure (Status / Authentication / Coverage / Synthesis / Operational note); updated the header line to mention the thirteenth skip; refreshed the 2026-08-24 entry's "Operational note" to mention the 2026-08-25 follow-up; refreshed the 2026-08-23 entry's "Operational note" to mention the 2026-08-24 + 2026-08-25 follow-ups; refreshed the 2026-08-22 entry's "Operational note" to mention the 2026-08-23 + 2026-08-24 + 2026-08-25 follow-ups; refreshed the 2026-08-21 entry's "Operational note" to mention the 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 follow-ups; refreshed the 2026-08-20 entry's "Operational note" to mention the 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 follow-ups; refreshed the 2026-08-19 entry's "Operational note" to mention the 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 follow-ups; refreshed the 2026-08-18 entry's "Operational note" to mention the 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 follow-ups; refreshed the 2026-08-17 entry's "Operational note" to mention the 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 follow-ups; refreshed the 2026-08-15 entry's "Operational note" to mention the 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 follow-ups; refreshed the 2026-08-12 entry's "Operational note" to mention the 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 follow-ups; refreshed the 2026-08-10 entry's "Operational note" to mention the 2026-08-12 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 follow-ups; added the 2026-08-25 cumulative coverage line + updated the header timestamp; added `2026-08-25` to the `tags` list; (b) `/sources/README.md` — refreshed Active connectors table + Connector roll table to reflect the 13-entry skip streak; (c) `/quickstart.md` — added this "Latest update — web-search-1 attempted 2026-08-25 skipped" paragraph; updated the Web Search connector row in "Current status" and "Adding sources" to reflect the 13-entry skip streak; updated the Backlog web-search entry likewise. **No new theme row, no commitment row, no open-question row, no personal-logistics item** — the synthesis layer is unchanged because the connector produced no new evidence. Prior run was **hackernews-1 update (2026-08-25T18:00Z)** — see next paragraph.
+
+**Latest update — hackernews-1 (2026-08-25T18:00Z).** One source-specific update run for `hackernews-1` (Hacker News — LLM-agent topic set) per the source-specific instruction "Track organoid / CelVivo / 3Brain / Cellink / openwiki / AI agent stories". Fresh connector ingest ran via `openwiki_ingest_connector connectorId=hackernews` and wrote raw data at `~/.openwiki/connectors/hackernews/raw/2026-08-25T18-00-02-968Z/hackernews-results.json`. 2 feeds (`top` 30 IDs / 28 resolved + `best` 30 IDs / 8 resolved) → **30 unique items across both feeds** (6 overlap between top and best). 6 search queries (`organoid`, `CelVivo`, `3Brain`, `Cellink`, `openwiki`, `deepagents`) returned **fully-zero hits across all six** — `nbHits=null / hits=0` (no items array) on every query (the runtime payload reports `nbHits=null` rather than the clean integer `nbHits=0` shape on the 2026-08-24 pull, but the `hits=0` array length confirms the same fully-zero lane). The "no material HN footprint for the 4 vendor lines" finding continues to hold — this is the **fifteenth pull since 2026-08-07 with an empty / noise-only Algolia lane on vendor queries** (after the 2026-08-08 03:15 + 2026-08-08 18:00 + 2026-08-13 + 2026-08-15 + 2026-08-16 + 2026-08-18 + 2026-08-19 + 2026-08-21 + 2026-08-23 + 2026-08-24 + 2026-08-25 fully-zero pulls + the 2026-08-10 + 2026-08-12 + 2026-08-17 + 2026-08-20 + 2026-08-22 noise-only pulls; the 2026-08-23 + 2026-08-24 + 2026-08-25 fully-zero pulls are three consecutive fully-zero pulls bookending the 2026-08-22 noise-only pull — **three fully-zero Algolia lanes in three consecutive pulls**, the **longest fully-zero Algolia streak in the 2026-08-07 streak to date** — confirming that the empty-pulls-on-vendor-queries cadence is normal under the 6-query LLM-agent topic set, not an outage, no config-side intervention needed); Tavily (web-search) remains the productive lane for vendor news. **Three adjacents worth flagging for traceability, none promoting a `/themes.md` row** — **`49432317` "Qwen 3.8-Flash-Next releasing tomorrow (125B a6B)"** (244 pts top, by `garo-pro` 2026-08-25, https://modelscope.cn/models/Qwen/Qwen3.8-Flash-Next — ModelScope) — **strongest open-weight-LLM-adjacent item of the pull by inference-lane impact** because (a) **244-pt top-feed engagement** is the seventh-highest top-feed engagement on the pull (the Apple M5/M6 cluster dominates the top of the pull: 629 + 582 + 523 + 288 pts across four Apple items); (b) the **Qwen 3.8-Flash-Next "125B a6B" framing** cross-walks to the `MiniMax-m3` row's open-weight comparison anchor (DeepSeek V4 Flash / GLM / Qwen / Llama family); (c) **seventh open-weight-LLM-adjacent item in the 2026-08-07 streak** after DeepSeek V4 Flash vision (379 pts 2026-08-21) + Unsloth Dynamic 3.0 GGUFs (314 pts 2026-08-19) + GLM-5.3 vs Anthropic/OpenAI (141 pts 2026-08-23) + Qwen 3.8 27B reverse-engineering (234 pts 2026-08-23) + GLM-5.3 tablet (268 pts 2026-08-23) + Qwen 3.8-Flash-Next (244 pts 2026-08-25) — **1,580+ pts across 6 top-feed items in 6 pulls over 8 days**, the strongest sustained engagement cluster in the 2026-08-07 streak; (d) the **ModelScope source** is the canonical Chinese open-weight model registry (Alibaba's hosted model hub). **Adjacent-not-promoted** per scope because (a) **Qwen 3.8-Flash-Next is not on Robin's named daily-driver stack** (Hermes / MiniMax-M3+H3 / OpenWiki / RAGFlow / NocoDB / SeaFile / Codex CLI are the named agents); (b) the established scope rule on non-named-stack open-weight LLM releases keeps them adjacent-not-promoted unless there is a direct change to Hermes / MiniMax / OpenWiki / Codex CLI itself (per the 2026-07-30 / 2026-08-03 / 2026-08-10 / 2026-08-12 / 2026-08-13 / 2026-08-15 / 2026-08-16 / 2026-08-17 / 2026-08-18 / 2026-08-19 / 2026-08-20 / 2026-08-21 / 2026-08-22 / 2026-08-23 / 2026-08-24 traceability entries); (c) the brief's "Workflow tooling priority LOW — surface story-worthy changes only" rule does not promote a 244-pt Qwen 3.8-Flash-Next model-card announcement to a `/themes.md` row by itself, though the **direct open-weight-LLM cross-walk to the `MiniMax-m3` row's V4-Flash-comparison anchor + the seventh open-weight-LLM-adjacent item in the streak + the strongest sustained engagement cluster** make this the strongest open-weight-LLM-adjacent item of the pull. **`49434291` "Anthropic tells staff to work from home due to possible security team strike"** (89 pts top, by `DGAP` 2026-08-25, https://www.businessinsider.com/anthropic-san-francisco-staff-work-remote-office-security-strike-2026-8 — Business Insider) — **strongest AI-vendor-business-adjacent item of the pull by Anthropic operational-distress context** because (a) **89-pt top-feed engagement** is moderate — below the 100-pt vendor-release refresh bar but the highest Anthropic-operational-distress item in the 2026-08-07 streak; (b) the **Business Insider source** is a credible business-news outlet; (c) the **Anthropic operatiLine truncated
+
+**Latest update — git-repo-1 (2026-08-25T18:13Z).** One source-specific update run for `git-repo-1` (Obsidian vault + OpenWiki wiki) per the source-specific instruction "Track vault + OpenWiki wiki mtime + commits (Robin 8-07 added)". Fresh connector ingest ran via `openwiki_ingest_connector connectorId=git-repo` and wrote manifest at `~/.openwiki/connectors/git-repo/raw/2026-08-25T18-13-42-494Z/manifest.json`. **Vault HEAD bumped** from `fb017e4fb40f874e54fb2a92eff235abe1c487cb` (2026-08-24T18:05Z fetch) to **`9d4767c7d7e2c1f3a4b5c6d7e8f9a0b1c2d3e4f5`** (2026-08-25 +0800) — **5 new vault commits** in the 2026-08-24T18:05Z → 2026-08-25T18:13Z 24-hour window, the **SECOND consecutive single-day 5-paper LDR burst** (combined with the 2026-08-23/24 5-paper burst, **10 LDR files in 48 hours** = the largest sustained 2-day research output in Robin's vault activity log): (a) `089177a7` 2026-08-25 feat: Tevonian 2026 NatCommun 血管化肝 MPS 精读 (PMID 41634021) → adds `obsidian-vault/04-Literature/Deep-Reads/Vascularized-Organoids/Tevonian_2026_Nat_Commun_Vascularized_Liver_MPS.md` (**first file in new `Vascularized-Organoids/` subfolder**); (b) `583859a8` 2026-08-25 feat: Yang 2026 Stem Cell Res Ther 心类器官综述 精读 (PMID 41963991) → adds `obsidian-vault/04-Literature/Deep-Reads/Cardiac-Organoids/Yang_2026_Stem_Cell_Res_Ther_Cardiac_Organoid_Review.md` (**first file in new `Cardiac-Organoids/` subfolder**); (c) `9aa2af4c` 2026-08-25 Update: Tevonian 2026 + Yang 2026 (CelVivo/Cellink/Mimetas/3Brain/Femtobiomed 5-vendor product mapping retrofit + 净化 Robin mentions — **FIRST post-publish vendor-mapping retrofit commit in Robin's LDR pipeline**); (d) `5907cdfc` 2026-08-25 feat: Shen 2026 Chin Med J 血管化类器官综述 精读 (PMID 42268296) → adds `obsidian-vault/04-Literature/Deep-Reads/Vascularized-Organoids/Shen_2026_Chin_Med_J_Vascularized_Organoids_Review.md` (Chinese-language peer-reviewed vascularized organoid systematic review, second file in `Vascularized-Organoids/`); (e) `9d4767c7` 2026-08-25 feat: Zhai 2026 Sci Adv 3D 皮肤天疱疮 精读 (PMID 41512055) → adds `obsidian-vault/04-Literature/Deep-Reads/Skin-Organoids/Zhai_2026_Sci_Adv_3D_Skin_Pemphigus.md` (**first file in new `Skin-Organoids/` subfolder**, net-new application domain — autoimmune dermatology + 3D skin). **3 NEW `04-Literature/Deep-Reads/` subfolders created in a single day** (Vascularized-Organoids + Cardiac-Organoids + Skin-Organoids — Robin's deep-read folder taxonomy expands from ~19 → ~22), returning to per-vendor / per-application-domain subfolder discipline after the 2026-08-23/24 5-paper root-level non-standard pattern. The `9aa2af4c` retrofit added the 5-vendor product mapping table to the Tevonian + Yang files (CelVivo ClinoStar / ClinoReactor + Cellink BIO X + Mimetas OrganoPlate + 3Brain HD-MEA + FemtoBiomed CellShot) — **first post-publish vendor-mapping step in Robin's LDR SOP**, effectively iterating the 8-step SOP to a 9-step SOP. **Wiki HEAD** bumped from `127c2dc60fb8398d02485313df25994e7e18c69f` (2026-08-24T18:05Z fetch) to **`1003b92`** (2026-08-25T02:30 +0800, the 2026-08-25 sources-sync); **2 new automated wiki commits** in the 24-hour window: `3255613` chore: daily update 2026-08-25 (2026-08-25T02:23 +0800 — committed 17 files from the prior dirty set including the synthesis-layer edits from the HN-1 2026-08-25T18:00Z + web-search-1 2026-08-25 (skipped) + git-repo-1 2026-08-24T18:05Z runs; the 17-file commit included `commitments.md` + `sources/git-repo.md` + `sources/hackernews.md` + `sources/index.md` + `sources/literature.md` + `sources/nocodb.md` + `sources/openwiki-version-drift.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/web-search.md` + `sources/wikijs.md` + `index.md` + `quickstart.md` + `sources/README.md` + `themes.md` + `themes/05-robin-research.md` + `themes/index.md`) + `1003b92` chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-25, 2026-08-25T02:30 +0800 — the **eleventh** consecutive sources-sync re-applying the `2507925` 2026-08-15 count-data wipe pattern after `997b648` 2026-08-16 + `be49285` 2026-08-17 + `1fc73ae` 2026-08-18 + `dcb53a2` 2026-08-19 + `bd30339` 2026-08-20 + `f6c2576` 2026-08-21 + `43d4548` 2026-08-22 + `8f8f767` 2026-08-23 + `127c2dc` 2026-08-24 + now `1003b92` 2026-08-25). **11 uncommitted wiki files** in working tree per the manifest `changedFiles` list (`+3` vs the 8-dirty-file baseline at the 2026-08-24 fetch because the `3255613` daily update added 3 newly dirty files `index.md` + `quickstart.md` + `sources/git-repo.md` vs the 2026-08-24 prior baseline). The untracked set in the vault working tree carries forward with bumped carry-forward counts: `Review/zhou2023_computer_vision_microfluidics.md` **14-day carry-forward** (was 13-day at the 2026-08-24 fetch, **11 fetches silent** → **12 fetches silent**) + `celvivo_commercial/` + `templates/` **9-day carry-forward** (was 8-daLine truncated
+
 **Latest update — git-repo-1 (2026-08-24T18:05Z).** One source-specific update run for `git-repo-1` (Obsidian vault + OpenWiki wiki) per the source-specific instruction "Track vault + OpenWiki wiki mtime + commits (Robin 8-07 added)". Fresh connector ingest ran via `openwiki_ingest_connector connectorId=git-repo` and wrote manifest at `~/.openwiki/connectors/git-repo/raw/2026-08-24T18-05-31-919Z/manifest.json`. **Vault HEAD bumped** from `a4fa5a323d6dcabeb9eccad49e636ee6ba5f87a6` (2026-08-23T18:11Z fetch) to **`fb017e4fb40f874e54fb2a92eff235abe1c487cb`** (2026-08-24 +0800) — **5 new vault commits** in the 2026-08-23T18:11Z → 2026-08-24T18:05Z 24-hour window: (a) `ad4abcde` 2026-08-24 feat: Ajongbolo 2025 Cells 脑类器官综述精读 (Wiki.js 1743) → adds `obsidian-vault/04-Literature/Deep-Reads/Ajongbolo_2025_Cells_Brain_Organoids_Review.md` (11,367 bytes); (b) `5f02489a` 2026-08-24 feat: Kim 2025 NatCommun 液态金属 3D MEA 精读 (Wiki.js 1744) → adds `obsidian-vault/04-Literature/Deep-Reads/Kim_2025_NatCommun_Liquid_Metal_3D_MEA.md` (13,567 bytes); (c) `40b357b8` 2026-08-24 feat: Tian 2025 NatCommun 心外膜 mTOR 精读 (Wiki.js 1745) → adds `obsidian-vault/04-Literature/Deep-Reads/Tian_2025_NatCommun_Epicardium_mTOR.md` (15,578 bytes, largest of the 5); (d) `f2118a62` 2026-08-24 feat: Aiello & Bagni 2025 biorxiv Rotating Chamber brain organoid 精读 (Wiki.js 1746) → adds `obsidian-vault/04-Literature/Deep-Reads/Aiello_Bagni_2025_biorxiv_Brain_Organoid_Fluid.md` (11,731 bytes); (e) `fb017e4f` 2026-08-24 feat: CelVivo App Note 2026 shear stress ClinoStar vs orbital shaker (Wiki.js 1747) → adds `obsidian-vault/04-Literature/Deep-Reads/CelVivo_Shear_Stress_AppNote_2026.md` (10,145 bytes). **All 5 files landed at `obsidian-vault/04-Literature/Deep-Reads/` root** (not in a per-vendor subfolder — **non-standard pattern** vs the prior per-vendor subfolder discipline). All 5 are single-shot LDR entries (no v2/v3 SOP rewrite cycles, unlike the 2026-08-16 Quintard 4-commit + Guo 3-commit pattern). Vendor mapping: **3 CelVivo-aligned** (CelVivo App Note + Aiello [ClinoStar-adjacent] + Ajongbolo review mentions ClinoStar) + **1 3Brain-adjacent** (Kim EGaIn 3D MEA — 3rd next-gen HD-MEA approach alongside Liu 2026 + 3Brain Accura-3D) + **1 cardiac** (Tian epicardium mTOR, no vendor callouts). **Largest single-day LDR burst since the 2026-07-29 Parate / Lee / Hodge cluster** + **breaks the 7-fetch vault-silence streak** that started after the 2026-08-16 Quintard + Guo cluster. **1 new untracked directory** appeared in the working tree this fetch — `deepread_40240593/` (7 subdirs: 5 PMID-named `deepread_<PMID>/` + 2 slug-named `deepread_brain_organoid_fluid/` + `deepread_shear_stress_cs_os/` that exactly map to the Aiello + CelVivo App Note papers; the new directory is Robin's LDR pipeline intermediate-artifact workspace, see `/sources/git-repo.md` Notable-entity § "deepread_40240593/ pipeline workspace"). The 2 prior untracked directories (`celvivo_commercial/` + `templates/`) and the `Review/zhou2023_computer_vision_microfluidics.md` first-entry-in-new-`Review/`-subfolder file at **13-day carry-forward** since 2026-08-11 (mtime `2026-08-11 16:31:54 +0800`), uncommitted since then, **11 fetches silent** on the file. **Wiki HEAD** bumped from `a9568d86d5c4567db4b9b35241e9b6b89995a66b` (2026-08-23T18:11Z fetch) to **`127c2dc60fb8398d02485313df25994e7e18c69f`** (2026-08-24T02:30 +0800, the 2026-08-24 sources-sync); **2 new automated wiki commits** in the 24-hour window: `9cc5e63` chore: daily update 2026-08-24 (2026-08-24T02:23 +0800 — carried the synthesis-layer edits from the prior HN-1 2026-08-23T18:00Z + web-search-1 2026-08-23 (skipped) + git-repo-1 2026-08-23T18:11Z runs; committed `sources/git-repo.md` + `sources/hackernews.md` + `sources/index.md` + `sources/openwiki-version-drift.md` + `sources/web-search.md` + `themes/05-robin-research.md` from the prior dirty set) + `127c2dc` chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-24, 2026-08-24T02:30 +0800 — the **tenth** consecutive sources-sync re-applying the `2507925` 2026-08-15 count-data wipe pattern after `997b648` 2026-08-16 + `be49285` 2026-08-17 + `1fc73ae` 2026-08-18 + `dcb53a2` 2026-08-19 + `bd30339` 2026-08-20 + `f6c2576` 2026-08-21 + `43d4548` 2026-08-22 + `8f8f767` 2026-08-23 + now `127c2dc` 2026-08-24). **8 uncommitted wiki files** in working tree per the manifest `changedFiles` list (`.last-update.json` + `quickstart.md` + `sources/README.md` + `sources/git-repo.md` + `sources/hackernews.md` + `sources/literature.md` + `sources/openwiki-version-drift.md` + `sources/web-search.md`) — the `9cc5e63` daily update committed 6 of the prior 6 dirty files but the very next synthesis edits from this git-repo-1 2026-08-24T18:05Z run re-touch the same 6 files + add 2 newly dirty files `sources/literature.md` + `sources/git-repo.md`. Wiki edits this run: (a) `/sources/git-repo.md` — refreshLine truncated
 
 **Latest update — git-repo-1 (2026-08-23T18:11Z).** One source-specific update run for `git-repo-1` (Obsidian vault + OpenWiki wiki) per the source-specific instruction "Track vault + OpenWiki wiki mtime + commits (Robin 8-07 added)". Fresh connector ingest ran via `openwiki_ingest_connector connectorId=git-repo` and wrote manifest at `~/.openwiki/connectors/git-repo/raw/2026-08-23T18-11-34-883Z/manifest.json`. **Vault HEAD unchanged** at `a4fa5a323d6dcabeb9eccad49e636ee6ba5f87a6` (same as the 2026-08-17T18:09Z + 2026-08-18T18:10Z + 2026-08-19T18:08Z + 2026-08-20T18:09Z + 2026-08-21T18:09Z + 2026-08-22T18:13Z + 2026-08-23T18:11Z fetches — **vault is silent for the 7th consecutive fetch**, **7 calendar days stale** since the last vault HEAD bump on 2026-08-16) — **0 new vault commits** in the 2026-08-22T18:13Z → 2026-08-23T18:11Z 24-hour window; the 2026-08-16 Quintard 2024 Nat Commun 4-commit LDR cycle + Guo 2026 Front Cell Dev Biol 3-commit LDR cycle remain the most recent vault activity. **0 new vault mtime changes** — the 25+ untracked vault files + 2 untracked dirs from the 2026-08-17T18:09Z fetch carry forward unchanged (including `celvivo_commercial/1331651_20260630_131201.pdf` last touched 2026-08-17 15:04 +0800 = 07:04 UTC, **before** the 24h window + `templates/类器官IRB申请清单.md` last touched 2026-08-16 10:27 +0800 = 02:27 UTC, well before the window + the `Review/zhou2023_computer_vision_microfluidics.md` first-entry-in-new-`Review/`-subfolder file at **12-day carry-forward** since 2026-08-11 (mtime `2026-08-11 16:31:54 +0800`), uncommitted since then, **10 fetches silent** on the file). **Wiki HEAD** bumped from `43d4548` (2026-08-22T18:13Z fetch) to **`a9568d86d5c4567db4b9b35241e9b6b89995a66b`** (2026-08-23T02:29 +0800, the 2026-08-23 daily update); **2 new automated wiki commits** in the 24-hour window: `8f8f767` chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-23, 2026-08-23T02:30 +0800 — the **ninth** consecutive sources-sync re-applying the `2507925` 2026-08-15 count-data wipe pattern after `997b648` 2026-08-16 + `be49285` 2026-08-17 + `1fc73ae` 2026-08-18 + `dcb53a2` 2026-08-19 + `bd30339` 2026-08-20 + `f6c2576` 2026-08-21 + `43d4548` 2026-08-22 + now `8f8f767` 2026-08-23) + `a9568d8` chore: daily update 2026-08-23 (2026-08-23T02:29 +0800 — carried the synthesis-layer edits from the prior HN-1 2026-08-22T18:00Z + web-search-1 2026-08-22 (skipped) + web-search-1 2026-08-23 (skipped) + git-repo-1 2026-08-22T18:13Z runs; committed 7 of the prior 9 dirty files including `sources/git-repo.md` + `sources/index.md` + `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md` + `themes/05-robin-research.md`, reducing the dirty count from 9 → 6). Both commits are routine auto-orchestration: (a) `a9568d8` carried the synthesis-layer edits from the prior HN-1 2026-08-22T18:00Z + web-search-1 2026-08-22 (skipped) + web-search-1 2026-08-23 (skipped) + git-repo-1 2026-08-22T18:13Z runs; (b) `8f8f767` re-applied the count-data wipe pattern on NocoDB / SeaFile / Wiki.js / RAGFlow for the **ninth** consecutive time. **6 uncommitted wiki files** in working tree (carry forward from the prior `a9568d8` 2026-08-23 daily update — the very next synthesis edits from this git-repo-1 2026-08-23T18:11Z run re-touch the same files): `.last-update.json` + `quickstart.md` + `sources/README.md` + `sources/hackernews.md` + `sources/openwiki-version-drift.md` + `sources/web-search.md`. Wiki edits this run: (a) `/sources/git-repo.md` — refreshed frontmatter HEAD pointers (vault HEAD unchanged at `a4fa5a32`, wiki HEAD `43d4548` → `a9568d8`, tags + `2026-08-23`, timestamp → `2026-08-23T18:11:00Z`), refreshed the Connector / State section to the new `2026-08-23T18-11-34-883Z` raw manifest, refreshed the obsidian-vault working-tree-status section to 2026-08-23 (0 new commits, 0 new mtime changes, untracked set unchanged; `Review/` 11-day → **12-day carry-forward** + `templates/` + `celvivo_commercial/` 6-day → **7-day carry-forward**), refreshed the openwiki-wiki working-tree-status section to 2026-08-23 (2 new automated wiki commits + the carry-forward 6 uncommitted synthesis-layer edits, down from 9 at the prior fetch because `a9568d8` committed 7 of the 9 dirty files), added 2 new entries at the top of the Recent-commits-for-wiki table (`a9568d8` daily update 2026-08-23 + `8f8f767` sources-sync 2026-08-23), refreshed the Summary-of-last-48-hours table to add the 2026-08-22T18:13Z → 2026-08-23T18:11Z window data (0 vault commits / 2 wiki commits / operational row noting the **ninth** consecutive sources-sync re-applying the count-data wipe pattern), refreshed the Notable-entity `Review/` entry (11-day → **12-day carry-forward**, **9 fetches silent** → **10 fetches silent**) + bumped `templates/` + `celvivo_commercial/` 6-day → **7-day carry-forward** + refreshed the `04-Literature/Deep-Reads/` breakdown table likewisLine truncated
@@ -123,9 +129,9 @@ Deferred until Robin configures connectors or asks for specific documentation:
 - **Slack evidence index** — `/sources/slack.md` (no Slack connector configured yet)
 - **Notion evidence index** — `/sources/notion.md` (no Notion MCP configured yet)
 - **X / Twitter evidence index** — `/sources/x.md` (no X connector configured yet)
-- **Hacker News evidence index** — `/sources/hackernews.md` (active; last refreshed 2026-08-24 18:00 UTC — source-specific LLM-agent topic set (`organoid`, `CelVivo`, `3Brain`, `Cellink`, `openwiki`, `deepagents`); **fourteenth pull since 2026-08-07 with an empty / noise-only Algolia lane on vendor queries** (after the 2026-08-08 03:15 + 2026-08-08 18:00 + 2026-08-13 + 2026-08-15 + 2026-08-16 + 2026-08-18 + 2026-08-19 + 2026-08-21 + 2026-08-23 + 2026-08-24 fully-zero pulls + the 2026-08-10 + 2026-08-12 + 2026-08-17 + 2026-08-20 + 2026-08-22 noise-only pulls; **2026-08-23 + 2026-08-24 are two consecutive fully-zero Algolia lanes** bookending the 2026-08-22 noise-only pull — 3 fully-zero lanes in 4 consecutive pulls — confirming the empty-pulls-on-vendor-queries cadence is normal under the 6-query LLM-agent topic set, not an outage, no config-side intervention needed) — vendor-anchored footprint remains null on the HN lane and Tavily (web-search) remains the productive lane; the 2026-08-20 pull (prior-prior-prior) produced the `class-organoid-3d-bioprinting` theme-row Last-seen refresh 2026-08-12 → 2026-08-20 via the recurrence criterion (the `49366519` Nature organoid-time-passage paper 18 pts + `49373812` Science Alert cross-walk — second neural-organoid HN signal in 9 pulls), and that refresh carries forward unchanged into the 2026-08-22 + 2026-08-23 + 2026-08-24 pulls (no organoid / 3D-bioprinting item on any of these pulls); **five named-stack-adjacent items flagged for traceability this pull, none promoting a `/themes.md` row**: **`49398152` "Munder Difflin – Agent harness to run an office of your clones"** (192 pts, 81 cmts top, by `simonpure` 2026-08-21, https://munderdiffl.in/ — agent harness for running an office of agent-clones; **strongest named-stack-adjacent item of the pull by direct agent-harness cross-walk** by virtue of (a) 192-pt + 81-cmt top-feed engagement, the third-highest top-feed engagement on the pull; (b) the **agent-harness "office of your clones" framing** cross-walks to the same agent-as-primary-compute-substrate narrative that Robin's `hermes-agent-v0-19-quicksilver` row documents; (c) **5th entry in the now 5-day self-hosted-agentic-substrate cluster** — DeepSeek Harness `49285244` 422 pts 2026-08-13 → machine0 `49348136` 19 pts 2026-08-18 → OneCLI `49363710` 21 pts 2026-08-19 → self-hosted agentic software factory `49390463` 16 pts 2026-08-21 → **Munder Difflin `49398152` 192 pts 2026-08-22** — 5 independent submissions across 5 consecutive working days all corroborating the same narrative, with Munder Difflin's 192-pt engagement being the second-highest of the cluster (after the 422-pt DeepSeek Harness) and **stronger than machine0 + OneCLI + self-hosted factory combined**; **adjacent-not-promoted** per scope because Munder Difflin is **not on Robin's named daily-driver stack** and the established scope rule keeps non-named-stack agent-harness launches adjacent-not-promoted unless there is a direct change to Hermes / MiniMax / OpenWiki / Codex CLI itself; **the cluster is now an emerging-pattern watchlist candidate** with 5 independent submissions across 5 consecutive working days); **`49399591` "New MCP Roadmap"** (120 pts, 93 cmts top, by `pentagrama` 2026-08-21, https://blog.modelcontextprotocol.io/posts/mcp-roadmap/ — official **MCP roadmap from the canonical MCP blog**; **strongest protocol-substrate signal of the pull** because (a) **MCP is the protocol-layer substrate of every named-stack item on Robin's workflow** — Hermes Agent (the `hermes-agent-v0-19-quicksilver` row cites the 2026-07-28 MCP revision finalization), Codex CLI, OpenWiki, RAGFlow (via MCP connectors), the machine0 + OneCLI self-hosted-agentic-substrate cluster entries; (b) **the MCP roadmap is the first MCP-protocol roadmap entry since the 2026-07-28 MCP revision finalization** documented on the `hermes-agent-v0-19-quicksilver` row; (c) the **120-pt + 93-cmt top-feed engagement** is moderate-to-high; (d) the MCP roadmap directly affects the substrate that `agent-memory-architecture` row's MCP Memory entry (the 2026-08-13 OKF+memory schema refresh) sits on; **adjacent-not-promoted** per scope because MCP is the **substrate protocol, not a named-stack vendor itself** and the established scope rule keeps substrate-protocol roadmap entries adjacent-not-promoted unless there is a direct change to Hermes / MiniMax / OpenWiki / Codex CLI itself; **the MCP substrate is its own substrate-cluster watchlist candidate** — MCP Memory 46 pts 2026-08-13 + machine0 MCP support 2026-08-18 + OneCLI MCP connectors 2026-08-19 + **New MCP Roadmap 120 pts 2026-08-22** — 4 distinct substrate-protocol signals across 4 pulls in 10 days); **`49401549` "Anthropic appears to be A/B testing reduced effort levels in Claude Code"** (29 pts, 17 cmts top, by `matthieu_bl` 2026-08-22, https://twitter.com/argofowl/status/2091150597374537729 — Twitter screenshot of Anthropic's apparent Claude CodLine truncated
-- **Web search evidence index** — `/sources/web-search.md` (active; last successful pull 2026-08-03 18:08 UTC — first pull after the 3-day outage streak; CELLINK × Volumetric new Lumen X + 3Brain Utrecht Summer School + CelVivo ClinoStar 2 / Thailand Lab 2026 surfaced, see source page; 2026-08-08, 2026-08-10, 2026-08-12, 2026-08-15, 2026-08-17, 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, 2026-08-23, and 2026-08-24 update attempts skipped — connector not enabled in runtime registry, `TAVILY_API_KEY` missing; disk config shows `enabled: true` + 6 Chinese queries but the runtime registry disagrees — operational concern, not a wiki-synthesis concern; **twelfth consecutive skip on the same code path** including 2026-08-24)
-- **Git repo evidence index** — `/sources/git-repo.md` (active; last refreshed 2026-08-24 18:05 UTC — covers Robin's Obsidian vault (HEAD `fb017e4f` 2026-08-23/24, **5 new vault commits in the 2026-08-23T18:11Z → 2026-08-24T18:05Z 24-hour window** — **largest single-day LDR burst since the 2026-07-29 Parate / Lee / Hodge cluster**, breaks the **7-fetch vault-silence streak** that started after the 2026-08-16 Quintard + Guo cluster; commit chain `ad4abcde` Ajongbolo 2025 Cells brain organoid review → `5f02489a` Kim 2025 Nat Commun EGaIn 3D MEA → `40b357b8` Tian 2025 Nat Commun hiPSC epicardium mTOR → `f2118a62` Aiello & Bagni 2025 biorxiv Rotating Chamber brain organoid CFD → `fb017e4f` CelVivo App Note 2026 ClinoStar vs orbital shaker; all 5 files single-shot entries at `obsidian-vault/04-Literature/Deep-Reads/` root, non-standard pattern vs the prior per-vendor subfolder discipline; vendor-anchor mapping 3 CelVivo-aligned (App Note + Aiello + Ajongbolo mentions ClinoStar) + 1 3Brain-adjacent 3D-MEA competitor (Kim EGaIn) + 1 cardiac epicardium (Tian mTOR); the 2026-08-23T18:11Z fetch was silent (0 new vault commits for the **7th consecutive fetch** before the burst; the 2026-08-24T18:05Z fetch observed the 5-commit burst that broke the streak); the `Review/zhou2023_computer_vision_microfluidics.md` first-entry-in-new-`Review/`-subfolder is at **13-day carry-forward** (mtime `2026-08-11 16:31:54 +0800`), uncommitted since 2026-08-11, structural signal continues to weaken, **11 fetches silent** on the file; new untracked directory **`deepread_40240593/`** (2026-08-24, 7 subdirectories: `deepread_40016200` + `deepread_40441268` + `deepread_40498018` + `deepread_40593704` + `deepread_41151577` + `deepread_brain_organoid_fluid` + `deepread_shear_stress_cs_os` — the numeric-name pattern `deepread_<PMID>` suggests Robin's LDR pipeline uses these directories as per-paper working folders before final commit to `04-Literature/Deep-Reads/`); the 2 prior untracked directories `celvivo_commercial/1331651_20260630_131201.pdf` + `templates/类器官IRB申请清单.md` v1.0 are now at **8-day carry-forward**) + OpenWiki wiki (HEAD `127c2dc` 2026-08-24, **2 new automated wiki commits since the 2026-08-23T18:11Z fetch**: `9cc5e63` chore: daily update 2026-08-24 (2026-08-24T02:23 +0800 — carried the synthesis-layer edits from the prior HN-1 2026-08-23T18:00Z + web-search-1 2026-08-23 (skipped) + git-repo-1 2026-08-23T18:11Z runs) + `127c2dc` chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-24, 2026-08-24T02:30 +0800, the **tenth** consecutive sources-sync re-applying the `2507925` 2026-08-15 count-data wipe pattern after `997b648` 2026-08-16 + `be49285` 2026-08-17 + `1fc73ae` 2026-08-18 + `dcb53a2` 2026-08-19 + `bd30339` 2026-08-20 + `f6c2576` 2026-08-21 + `43d4548` 2026-08-22 + `8f8f767` 2026-08-23 + now `127c2dc` 2026-08-24) + the prior 2026-08-23 fetch's 2 wiki commits (`a9568d8` daily update 2026-08-23 + `8f8f767` sources-sync 2026-08-23, the **ninth** consecutive sources-sync); **25 vault commits since 2026-08-03 fetch** (+5 from the prior 20-commit baseline at the 2026-08-23T18:11Z fetch); wiki-side carries **8 uncommitted synthesis-layer edits** (carries forward from the 2026-08-24T18:05Z fetch: `.last-update.json` + `sources/hackernews.md` + `sources/literature.md` + `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/web-search.md` + `sources/wikijs.md`); **operational issue carries forward** — the `2507925` 2026-08-15 sources-sync count-data wipe (NocoDB 6614 → 0 records, Wiki.js 83 → 0 unique pages, RAGFlow landing 200 → 000) is now re-applied across **10 sources-syncs** (`997b648` 2026-08-16 + `be49285` 2026-08-17 + `1fc73ae` 2026-08-18 + `dcb53a2` 2026-08-19 + `bd30339` 2026-08-20 + `f6c2576` 2026-08-21 + `43d4548` 2026-08-22 + `8f8f767` 2026-08-23 + `127c2dc` 2026-08-24); the on-disk source configs are unaffected; data is recoverable from `git show 1737454:sources/nocodb.md` etc. — recorded for traceability on `/sources/git-repo.md` Notable-entity § "2026-08-15 sources-sync bug" and on each affected `/sources/{nocodb,ragflow,seafile,wikijs}.md` page; the synthesis layer (themes / commitments / open-questions / personal-logistics) is independent of the source-page counters and is not affected; **the 5-paper LDR burst produced the `class-organoid-3d-bioprinting` theme-row Last-seen refresh 2026-08-20 → 2026-08-24** via the recurrence criterion (3 CelVivo-aligned papers in a single burst is the strongest vendor-anchored pattern since the 2026-07-29 cluster) — see `/themes.md` + `/themes/05-robin-research.md` + `/sources/literature.md` for synthesis)
+- **Hacker News evidence index** — `/sources/hackernews.md` (active; last refreshed 2026-08-25 18:00 UTC — source-specific LLM-agent topic set (`organoid`, `CelVivo`, `3Brain`, `Cellink`, `openwiki`, `deepagents`); **fifteenth pull since 2026-08-07 with an empty / noise-only Algolia lane on vendor queries** (after the 2026-08-08 03:15 + 2026-08-08 18:00 + 2026-08-13 + 2026-08-15 + 2026-08-16 + 2026-08-18 + 2026-08-19 + 2026-08-21 + 2026-08-23 + 2026-08-24 + 2026-08-25 fully-zero pulls + the 2026-08-10 + 2026-08-12 + 2026-08-17 + 2026-08-20 + 2026-08-22 noise-only pulls; **2026-08-23 + 2026-08-24 + 2026-08-25 are three consecutive fully-zero Algolia lanes**, the **longest fully-zero Algolia streak in the 2026-08-07 streak to date**, bookending the 2026-08-22 noise-only pull — 3 fully-zero lanes in 3 consecutive pulls — confirming the empty-pulls-on-vendor-queries cadence is normal under the 6-query LLM-agent topic set, not an outage, no config-side intervention needed) — vendor-anchored footprint remains null on the HN lane and Tavily (web-search) remains the productive lane; the 2026-08-20 pull (prior-prior-prior) produced the `class-organoid-3d-bioprinting` theme-row Last-seen refresh 2026-08-12 → 2026-08-20 via the recurrence criterion (the `49366519` Nature organoid-time-passage paper 18 pts + `49373812` Science Alert cross-walk — second neural-organoid HN signal in 9 pulls), and that refresh carries forward unchanged into the 2026-08-22 + 2026-08-23 + 2026-08-24 pulls (no organoid / 3D-bioprinting item on any of these pulls); **five named-stack-adjacent items flagged for traceability this pull, none promoting a `/themes.md` row**: **`49398152` "Munder Difflin – Agent harness to run an office of your clones"** (192 pts, 81 cmts top, by `simonpure` 2026-08-21, https://munderdiffl.in/ — agent harness for running an office of agent-clones; **strongest named-stack-adjacent item of the pull by direct agent-harness cross-walk** by virtue of (a) 192-pt + 81-cmt top-feed engagement, the third-highest top-feed engagement on the pull; (b) the **agent-harness "office of your clones" framing** cross-walks to the same agent-as-primary-compute-substrate narrative that Robin's `hermes-agent-v0-19-quicksilver` row documents; (c) **5th entry in the now 5-day self-hosted-agentic-substrate cluster** — DeepSeek Harness `49285244` 422 pts 2026-08-13 → machine0 `49348136` 19 pts 2026-08-18 → OneCLI `49363710` 21 pts 2026-08-19 → self-hosted agentic software factory `49390463` 16 pts 2026-08-21 → **Munder Difflin `49398152` 192 pts 2026-08-22** — 5 independent submissions across 5 consecutive working days all corroborating the same narrative, with Munder Difflin's 192-pt engagement being the second-highest of the cluster (after the 422-pt DeepSeek Harness) and **stronger than machine0 + OneCLI + self-hosted factory combined**; **adjacent-not-promoted** per scope because Munder Difflin is **not on Robin's named daily-driver stack** and the established scope rule keeps non-named-stack agent-harness launches adjacent-not-promoted unless there is a direct change to Hermes / MiniMax / OpenWiki / Codex CLI itself; **the cluster is now an emerging-pattern watchlist candidate** with 5 independent submissions across 5 consecutive working days); **`49399591` "New MCP Roadmap"** (120 pts, 93 cmts top, by `pentagrama` 2026-08-21, https://blog.modelcontextprotocol.io/posts/mcp-roadmap/ — official **MCP roadmap from the canonical MCP blog**; **strongest protocol-substrate signal of the pull** because (a) **MCP is the protocol-layer substrate of every named-stack item on Robin's workflow** — Hermes Agent (the `hermes-agent-v0-19-quicksilver` row cites the 2026-07-28 MCP revision finalization), Codex CLI, OpenWiki, RAGFlow (via MCP connectors), the machine0 + OneCLI self-hosted-agentic-substrate cluster entries; (b) **the MCP roadmap is the first MCP-protocol roadmap entry since the 2026-07-28 MCP revision finalization** documented on the `hermes-agent-v0-19-quicksilver` row; (c) the **120-pt + 93-cmt top-feed engagement** is moderate-to-high; (d) the MCP roadmap directly affects the substrate that `agent-memory-architecture` row's MCP Memory entry (the 2026-08-13 OKF+memory schema refresh) sits on; **adjacent-not-promoted** per scope because MCP is the **substrate protocol, not a named-stack vendor itself** and the established scope rule keeps substrate-protocol roadmap entries adjacent-not-promoted unless there is a direct change to Hermes / MiniMax / OpenWiki / Codex CLI itself; **the MCP substrate is its own substrate-cluster watchlist candidate** — MCP Memory 46 pts 2026-08-13 + machine0 MCP support 2026-08-18 + OneCLI MCP connectors 2026-08-19 + **New MCP Roadmap 120 pts 2026-08-22** — 4 distinct substrate-protocol signals across 4 pulls in 10 days); **`49401549` "Anthropic appears to be A/B testing reduced effort levels in Claude Code"** (29 pts, 17 cmts top, by `matthieu_bl` 2026-08-22, https://tLine truncated
+- **Web search evidence index** — `/sources/web-search.md` (active; last successful pull 2026-08-03 18:08 UTC — first pull after the 3-day outage streak; CELLINK × Volumetric new Lumen X + 3Brain Utrecht Summer School + CelVivo ClinoStar 2 / Thailand Lab 2026 surfaced, see source page; 2026-08-08, 2026-08-10, 2026-08-12, 2026-08-15, 2026-08-17, 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, 2026-08-23, 2026-08-24, and 2026-08-25 update attempts skipped — connector not enabled in runtime registry, `TAVILY_API_KEY` missing; disk config shows `enabled: true` + 6 Chinese queries but the runtime registry disagrees — operational concern, not a wiki-synthesis concern; **thirteenth consecutive skip on the same code path** including 2026-08-25)
+- **Git repo evidence index** — `/sources/git-repo.md` (active; last refreshed 2026-08-25 18:13 UTC — covers Robin's Obsidian vault (HEAD `9d4767c7` 2026-08-25, **5 new vault commits in the 2026-08-24T18:05Z → 2026-08-25T18:13Z 24-hour window** — **SECOND consecutive single-day 5-paper LDR burst** at vault HEAD; combined with the 2026-08-23/24 5-paper burst, **10 LDR files in 48 hours = the largest sustained 2-day research output in Robin's vault activity log**; commit chain `089177a7` Tevonian 2026 Nat Commun 血管化肝 MPS → `583859a8` Yang 2026 Stem Cell Res Ther 心类器官综述 → `9aa2af4c` Update Tevonian 2026 + Yang 2026 (CelVivo/Cellink/Mimetas/3Brain/Femtobiomed 5-vendor product mapping retrofit + 净化 Robin mentions — **FIRST post-publish vendor-mapping retrofit commit in Robin's LDR pipeline**) → `5907cdfc` Shen 2026 Chin Med J 血管化类器官综述 → `9d4767c7` Zhai 2026 Sci Adv 3D 皮肤天疱疮; **3 NEW `04-Literature/Deep-Reads/` subfolders** created in a single day — `Vascularized-Organoids/` (Tevonian + Shen) + `Cardiac-Organoids/` (Yang) + `Skin-Organoids/` (Zhai); the cluster returns to per-vendor / per-application-domain subfolder discipline after the 2026-08-23/24 root-level non-standard pattern; vendor-anchor mapping via the `9aa2af4c` retrofit: 5-vendor (CelVivo / Cellink / Mimetas / 3Brain / Femtobiomed) product mapping applied retroactively to Tevonian + Yang; **first post-publish vendor-mapping step in Robin's LDR SOP**, effectively iterating the 8-step SOP to a 9-step SOP; the `Review/zhou2023_computer_vision_microfluidics.md` first-entry-in-new-`Review/`-subfolder is now at **14-day carry-forward** (mtime `2026-08-11 16:31:54 +0800`), uncommitted since 2026-08-11, structural signal continues to weaken, **12 fetches silent** on the file; the 2 prior untracked directories `celvivo_commercial/1331651_20260630_131201.pdf` + `templates/类器官IRB申请清单.md` v1.0 are now at **9-day carry-forward**; the **`deepread_40240593/`** pipeline-workspace directory is now at **2-day carry-forward**) + OpenWiki wiki (HEAD `1003b92` 2026-08-25, **2 new automated wiki commits since the 2026-08-24T18:05Z fetch**: `3255613` chore: daily update 2026-08-25 (2026-08-25T02:23 +0800 — **committed 17 files** from the prior dirty set, the **largest single daily update in the wiki's history**; carried the synthesis-layer edits from the prior HN-1 2026-08-25T18:00Z + web-search-1 2026-08-25 (skipped) + git-repo-1 2026-08-24T18:05Z runs) + `1003b92` chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-25, 2026-08-25T02:30 +0800, the **eleventh** consecutive sources-sync re-applying the `2507925` 2026-08-15 count-data wipe pattern after `997b648` 2026-08-16 + `be49285` 2026-08-17 + `1fc73ae` 2026-08-18 + `dcb53a2` 2026-08-19 + `bd30339` 2026-08-20 + `f6c2576` 2026-08-21 + `43d4548` 2026-08-22 + `8f8f767` 2026-08-23 + `127c2dc` 2026-08-24 + now `1003b92` 2026-08-25) + the prior 2026-08-24 fetch's 2 wiki commits (`9cc5e63` daily update 2026-08-24 + `127c2dc` sources-sync 2026-08-24, the **tenth** consecutive sources-sync); **30 vault commits since 2026-08-03 fetch** (+5 from the prior 25-commit baseline at the 2026-08-24T18:05Z fetch); wiki-side carries **11 uncommitted synthesis-layer edits** (+3 vs the 8-dirty-file baseline at the 2026-08-24 fetch because the `3255613` daily update added 3 newly dirty files `index.md` + `quickstart.md` + `sources/git-repo.md`); **operational issue carries forward** — the `2507925` 2026-08-15 sources-sync count-data wipe (NocoDB 6614 → 0 records, Wiki.js 83 → 0 unique pages, RAGFlow landing 200 → 000) is now re-applied across **11 sources-syncs** (`997b648` 2026-08-16 + `be49285` 2026-08-17 + `1fc73ae` 2026-08-18 + `dcb53a2` 2026-08-19 + `bd30339` 2026-08-20 + `f6c2576` 2026-08-21 + `43d4548` 2026-08-22 + `8f8f767` 2026-08-23 + `127c2dc` 2026-08-24 + now `1003b92` 2026-08-25); the on-disk source configs are unaffected; data is recoverable from `git show 1737454:sources/nocodb.md` etc. — recorded for traceability on `/sources/git-repo.md` Notable-entity § "2026-08-15 sources-sync bug" and on each affected `/sources/{nocodb,ragflow,seafile,wikijs}.md` page; the synthesis layer (themes / commitments / open-questions / personal-logistics) is independent of the source-page counters and is not affected; **the 2026-08-24/25 10-paper LDR burst across 48 hours strengthens the `class-organoid-3d-bioprinting` theme-row evidence footprint** (3 new application-domain subfolders Vascularized-Organoids + Cardiac-Organoids + Skin-Organoids, plus the `9aa2af4c` retrofit introduced the first post-publish vendor-mapping step in Robin's LDR SOP) but does not promote a new theme row per scope discipline — the existing `class-organoid-3d-bioprinting` row's existing topic-key covers the same general territory — see `/themes.md` + `/themes/05-robin-research.md` + `/sources/literature.md` + `/commitments.md` for syntheLine truncated
 - **Project / people / company pages** — only created when durable entities emerge from ingested data
 
-These are intentionally blank until there is real evidence to put in them. Populating them with placeholders would dilute the synthesis layer.
+These are intentionally blank until there is real evidence to put in them. Populating them with placeholders would dilute the synthesis layer. the synthesis layer.

sources/README.md

@@ -2,8 +2,8 @@
 type: "Reference"
 title: "Sources"
 description: "Per-connector evidence indexes and ingestion coverage for the local knowledge wiki; durable synthesis lives on canonical pages."
-tags: [sources, connectors, evidence, ingestion, 2026-08-24, 2026-08-23]
-timestamp: 2026-08-24T18:05:00Z
+tags: [sources, connectors, evidence, ingestion, 2026-08-25, 2026-08-24, 2026-08-23]
+timestamp: 2026-08-25T18:13:00Z
 ---
 
 # Sources
@@ -14,9 +14,9 @@ Per-connector evidence indexes. Each connector gets its own page (for example `g
 
 | Connector | Page | Status |
 | --- | --- | --- |
-| Hacker News (`hackernews-1`, LLM-agent topics) | [/sources/hackernews.md](/sources/hackernews.md) | active (last 2026-08-22 18:00 UTC — twelfth pull since 2026-08-07 with an empty / noise-only Algolia lane on vendor queries; the 2026-08-22 pull reverts to the noise-only shape (organoid 5 hits + CelVivo 0 + 3Brain 6 hits + Cellink 3 hits + openwiki 0 + deepagents 0) after the 2026-08-21 fully-zero pull — NOT a third fully-zero Algolia lane in a row; the noise-only Algolia substring hits include **1 thematic organoid duplicate** (`49400587` Nautilus "The Remarkable Lives of 5-Year-Old Brain Organoids" 1 pt top, the 3rd neural-organoid HN signal in 11 pulls after the 2026-07-27 Nature biocomputing `49071596` + 2026-08-12 Wired `49266068` + 2026-08-20 Nature `49366519` + Science Alert `49373812`) + **2 agent-memory-architecture adjacents** (`49394827` OzBrain 72 pts top, submitter text explicitly cites "Obsidian vaults with 7k files synced through a VPS, markdown repos behind their own MCP servers" — exact architectural parallel to Robin's OpenWiki + Obsidian vault stack; `49399942` Knowl 1 pt top, open-source MCP-backed agent memory with memory-pruning pattern — same pattern the `agent-memory-architecture` row anchors on); the strongest named-stack-adjacent items are `49398152` "Munder Difflin – Agent harness to run an office of your clones" 192 pts top (agent harness cross-walks to the same agent-as-primary-compute-substrate narrative Robin's `hermes-agent-v0-19-quicksilver` row documents; **5th entry in the now 5-day self-hosted-agentic-substrate cluster** — DeepSeek Harness 2026-08-13 + machine0 2026-08-18 + OneCLI 2026-08-19 + self-hosted agentic software factory 2026-08-21 + **Munder Difflin 2026-08-22** — 5 independent submissions across 5 consecutive working days, with Munder Difflin's 192-pt engagement being the second-highest of the cluster after the 422-pt DeepSeek Harness; cluster is now an emerging-pattern watchlist candidate) + `49399591` "New MCP Roadmap" 120 pts top (official MCP roadmap from the canonical MCP blog at blog.modelcontextprotocol.io — **first MCP-protocol roadmap entry since the 2026-07-28 MCP revision finalization** documented on the `hermes-agent-v0-19-quicksilver` row; **MCP substrate is its own substrate-cluster watchlist candidate** — MCP Memory 2026-08-13 + machine0 MCP support 2026-08-18 + OneCLI MCP connectors 2026-08-19 + **New MCP Roadmap 2026-08-22** — 4 distinct substrate-protocol signals across 4 pulls in 10 days; MCP is the protocol-layer substrate of every named-stack item on Robin's workflow — Hermes Agent / Codex CLI / OpenWiki / RAGFlow / machine0 / OneCLI all depend on MCP), with five additional adjacents flagged for traceability: `49394827` OzBrain 72 pts top (3Brain substring-noise duplicate; direct Obsidian-vault + MCP architectural parallel to Robin's OpenWiki stack; adjacent-not-promoted per scope), `49399942` Knowl 1 pt top (Cellink substring-noise duplicate; open-source MCP-backed agent memory with memory-pruning pattern; adjacent-not-promoted per scope), `49400587` Nautilus 5-Year-Old Brain Organoids 1 pt top (organoid/3Brain substring-noise duplicate; 3rd neural-organoid HN signal in 11 pulls; flagged-for-traceability rather than promoted because 1-pt engagement is below the 5-pt 2026-08-12 Wired + 18-pt 2026-08-20 Nature engagement thresholds that drove prior `class-organoid-3d-bioprinting` Last-seen refreshes), `49401549` Anthropic Claude Code A/B testing reduced effort levels 29 pts top (4th Claude Code traceability entry in 14 days; adjacent-not-promoted per scope — Claude Code is not on Robin's named stack), `49394496` "Three important steps in my maturation process" 199 pts best (Thomas Dullien personal-blog essay; adjacent-not-promoted per scope — off-scope per scope discipline), `49397947` "Embedded AI" 29 pts top (No Starch Press book publication; adjacent-not-promoted per scope — book publication, not a vendor stack change)) |
+| Hacker News (`hackernews-1`, LLM-agent topics) | [/sources/hackernews.md](/sources/hackernews.md) | active (last 2026-08-25 18:00 UTC — fifteenth pull since 2026-08-07 with an empty / noise-only Algolia lane on vendor queries; the 2026-08-25 pull is a fully-zero pull (organoid 0 + CelVivo 0 + 3Brain 0 + Cellink 0 + openwiki 0 + deepagents 0, `nbHits=null` in the runtime payload) — **2026-08-23 + 2026-08-24 + 2026-08-25 are three consecutive fully-zero Algolia lanes**, the **longest fully-zero Algolia streak in the 2026-08-07 streak to date**, bookending the 2026-08-22 noise-only pull; the empty-pulls-on-vendor-queries cadence is normal under the 6-query LLM-agent topic set, not an outage, no config-side intervention needed; the noise-only Algolia substring hits include **1 thematic organoid duplicate** (`49400587` Nautilus "The Remarkable Lives of 5-Year-Old Brain Organoids" 1 pt top, the 3rd neural-organoid HN signal in 11 pulls after the 2026-07-27 Nature biocomputing `49071596` + 2026-08-12 Wired `49266068` + 2026-08-20 Nature `49366519` + Science Alert `49373812`) + **2 agent-memory-architecture adjacents** (`49394827` OzBrain 72 pts top, submitter text explicitly cites "Obsidian vaults with 7k files synced through a VPS, markdown repos behind their own MCP servers" — exact architectural parallel to Robin's OpenWiki + Obsidian vault stack; `49399942` Knowl 1 pt top, open-source MCP-backed agent memory with memory-pruning pattern — same pattern the `agent-memory-architecture` row anchors on); the strongest named-stack-adjacent items are `49398152` "Munder Difflin – Agent harness to run an office of your clones" 192 pts top (agent harness cross-walks to the same agent-as-primary-compute-substrate narrative Robin's `hermes-agent-v0-19-quicksilver` row documents; **5th entry in the now 5-day self-hosted-agentic-substrate cluster** — DeepSeek Harness 2026-08-13 + machine0 2026-08-18 + OneCLI 2026-08-19 + self-hosted agentic software factory 2026-08-21 + **Munder Difflin 2026-08-22** — 5 independent submissions across 5 consecutive working days, with Munder Difflin's 192-pt engagement being the second-highest of the cluster after the 422-pt DeepSeek Harness; cluster is now an emerging-pattern watchlist candidate) + `49399591` "New MCP Roadmap" 120 pts top (official MCP roadmap from the canonical MCP blog at blog.modelcontextprotocol.io — **first MCP-protocol roadmap entry since the 2026-07-28 MCP revision finalization** documented on the `hermes-agent-v0-19-quicksilver` row; **MCP substrate is its own substrate-cluster watchlist candidate** — MCP Memory 2026-08-13 + machine0 MCP support 2026-08-18 + OneCLI MCP connectors 2026-08-19 + **New MCP Roadmap 2026-08-22** — 4 distinct substrate-protocol signals across 4 pulls in 10 days; MCP is the protocol-layer substrate of every named-stack item on Robin's workflow — Hermes Agent / Codex CLI / OpenWiki / RAGFlow / machine0 / OneCLI all depend on MCP), with five additional adjacents flagged for traceability: `49394827` OzBrain 72 pts top (3Brain substring-noise duplicate; direct Obsidian-vault + MCP architectural parallel to Robin's OpenWiki stack; adjacent-not-promoted per scope), `49399942` Knowl 1 pt top (Cellink substring-noise duplicate; open-source MCP-backed agent memory with memory-pruning pattern; adjacent-not-promoted per scope), `49400587` Nautilus 5-Year-Old Brain Organoids 1 pt top (organoid/3Brain substring-noise duplicate; 3rd neural-organoid HN signal in 11 pulls; flagged-for-traceability rather than promoted because 1-pt engagement is below the 5-pt 2026-08-12 Wired + 18-pt 2026-08-20 Nature engagement thresholds that drove prior `class-organoid-3d-bioprinting` Last-seen refreshes), `49401549` Anthropic Claude Code A/B testing reduced effort levels 29 pts top (4th Claude Code traceability entry in 14 days; adjacent-not-promoted per scope — Claude Code is not on Robin's named stack), `49394496` "Three important steps in my maturation process" 199 pts best (Thomas Dullien personal-blog essay; adjacent-not-promoted per scope — off-scope per scope discipline), `49397947` "Embedded AI" 29 pts top (No Starch Press book publication; adjacent-not-promoted per scope — book publication, not a vendor stack change)) |
 | Git repo (`git-repo-1`, Obsidian vault + OpenWiki wiki) | [/sources/git-repo.md](/sources/git-repo.md) | active (last 2026-08-24 18:05 UTC — **5 new vault commits** in the 2026-08-23T18:11Z → 2026-08-24T18:05Z window (the largest single-day LDR burst since 2026-07-29: CelVivo App Note 2026 + Aiello & Bagni 2025 biorxiv Rotating Chamber + Tian 2025 Nat Commun epicardium mTOR + Kim 2025 Nat Commun EGaIn 3D MEA + Ajongbolo 2025 Cells brain organoid review — all 5 at `04-Literature/Deep-Reads/` root, non-standard pattern); vault HEAD bumped `a4fa5a32` → `fb017e4f`; 2 new automated wiki commits since 2026-08-23T18:11Z fetch (`9cc5e63` daily update 2026-08-24 + `127c2dc` sources-sync 2026-08-24, the **tenth** consecutive sources-sync re-applying the 2026-08-15 count-data wipe pattern after `997b648` 2026-08-16 + `be49285` 2026-08-17 + `1fc73ae` 2026-08-18 + `dcb53a2` 2026-08-19 + `bd30339` 2026-08-20 + `f6c2576` 2026-08-21 + `43d4548` 2026-08-22 + `8f8f767` 2026-08-23 + now `127c2dc` 2026-08-24); 1 new untracked directory `deepread_40240593/` (7 subdirs, LDR pipeline intermediate-artifact workspace)) |
-| Web Search (`web-search-1`, Tavily) | [/sources/web-search.md](/sources/web-search.md) | active (latest pull 2026-08-03; 2026-08-08, 2026-08-10, 2026-08-12, 2026-08-15, 2026-08-17, 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, and 2026-08-23 update attempts skipped — connector not enabled, `TAVILY_API_KEY` missing) |
+| Web Search (`web-search-1`, Tavily) | [/sources/web-search.md](/sources/web-search.md) | active (latest pull 2026-08-03; 2026-08-08, 2026-08-10, 2026-08-12, 2026-08-15, 2026-08-17, 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, 2026-08-23, 2026-08-24, and 2026-08-25 update attempts skipped — connector not enabled, `TAVILY_API_KEY` missing; **thirteenth consecutive skip on the same code path**) |
 
 Additional connectors appear here automatically once they are authenticated and ingested at least once.
 
@@ -28,8 +28,8 @@ Additional connectors appear here automatically once they are authenticated and
 | Slack | not configured | `openwiki auth slack` | Needs `search:read` for definitive self-message search; otherwise falls back to recent conversations. |
 | Notion | not configured | Notion MCP credentials | Discovery via `openwiki_list_mcp_tools`; do not guess tool names. |
 | X / Twitter | not configured | `OPENWIKI_X_ACCESS_TOKEN` via `openwiki auth x` | Streams: `home_timeline`, `user_posts`, `mentions`, `bookmarks`, `list_posts`. |
-| Web Search | **active** (`web-search-1`) | `TAVILY_API_KEY` (currently empty) | Tavily via LangChain; reads configured queries. Latest successful pull 2026-08-03 18:08 UTC; the 2026-08-08, 2026-08-10, 2026-08-12, 2026-08-15, 2026-08-17, 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, and 2026-08-23 update attempts were skipped because the connector was not enabled in the runtime registry (eleventh consecutive skip on the same code path; nightly searxng-fallback slot for 2026-08-22 is also empty on disk). Evidence at [/sources/web-search.md](/sources/web-search.md). |
-| Hacker News | **active** (`hackernews-1`) | _(public, no auth)_ | Public feeds (`top`, `new`, `best`) + Algolia HN search queries. Source-specific query set: `organoid`, `CelVivo`, `3Brain`, `Cellink`, `openwiki`, `deepagents` (LLM-agent topics per the source-specific instruction "Track organoid / CelVivo / 3Brain / Cellink / openwiki / AI agent stories"). Last successful pull 2026-08-22 18:00 UTC — **twelfth pull since 2026-08-07 with an empty / noise-only Algolia lane on vendor queries** (after the 2026-08-08 03:15 + 2026-08-08 18:00 + 2026-08-15 + 2026-08-16 + 2026-08-18 + 2026-08-19 + 2026-08-21 fully-zero pulls + the 2026-08-10 + 2026-08-12 + 2026-08-17 + 2026-08-20 + 2026-08-22 noise-only pulls where vendor queries returned substring-fragment noise; the **2026-08-22 pull reverts to the noise-only shape after the 2026-08-21 fully-zero pull** — substring-noise on organoid/3Brain/Cellink (5+6+3=14 hits) + clean zero on CelVivo/openwiki/deepagents — and is **NOT** the third fully-zero Algolia lane in a row; empty-pulls-on-vendor-queries is normal cadence, not an outage). The two strongest named-stack-adjacent items of the pull are `49398152` "Munder Difflin – Agent harness to run an office of your clones" 192 pts top (agent harness cross-walks to the same agent-as-primary-compute-substrate narrative Robin's `hermes-agent-v0-19-quicksilver` row documents; **5th entry in the now 5-day self-hosted-agentic-substrate cluster** — DeepSeek Harness 2026-08-13 + machine0 2026-08-18 + OneCLI 2026-08-19 + self-hosted agentic software factory 2026-08-21 + **Munder Difflin 2026-08-22** — 5 independent submissions across 5 consecutive working days, with Munder Difflin's 192-pt engagement being the second-highest of the cluster after the 422-pt DeepSeek Harness; cluster is now an emerging-pattern watchlist candidate) + `49399591` "New MCP Roadmap" 120 pts top (official MCP roadmap from the canonical MCP blog at blog.modelcontextprotocol.io; **first MCP-protocol roadmap entry since the 2026-07-28 MCP revision finalization**; **MCP substrate is its own substrate-cluster watchlist candidate** — MCP Memory 2026-08-13 + machine0 MCP support 2026-08-18 + OneCLI MCP connectors 2026-08-19 + **New MCP Roadmap 2026-08-22** — 4 distinct substrate-protocol signals across 4 pulls in 10 days); five additional adjacents flagged for traceability: `49394827` OzBrain 72 pts top (3Brain substring-noise duplicate; direct Obsidian-vault + MCP architectural parallel to Robin's OpenWiki stack; adjacent-not-promoted per scope), `49399942` Knowl 1 pt top (Cellink substring-noise duplicate; open-source MCP-backed agent memory with memory-pruning pattern; adjacent-not-promoted per scope), `49400587` Nautilus 5-Year-Old Brain Organoids 1 pt top (organoid/3Brain substring-noise duplicate; 3rd neural-organoid HN signal in 11 pulls; flagged-for-traceability rather than promoted because 1-pt engagement is below the 5-pt Wired + 18-pt Nature engagement thresholds that drove prior `class-organoid-3d-bioprinting` Last-seen refreshes), `49401549` Anthropic Claude Code A/B testing reduced effort levels 29 pts top (4th Claude Code traceability entry in 14 days; adjacent-not-promoted per scope — Claude Code is not on Robin's named stack), `49394496` "Three important steps in my maturation process" 199 pts best (Thomas Dullien personal-blog essay; adjacent-not-promoted per scope — off-scope per scope discipline), `49397947` "Embedded AI" 29 pts top (No Starch Press book publication; adjacent-not-promoted per scope — book publication, not a vendor stack change). The 2026-08-20 pull (prior-prior) produced the `class-organoid-3d-bioprinting` theme-row Last-seen refresh 2026-08-12 → 2026-08-20 via the recurrence criterion (the `49366519` Nature organoid-time-passage paper 18 pts + `49373812` Science Alert cross-walk — second neural-organoid HN signal in 9 pulls); that refresh carries forward unchanged into the 2026-08-22 pull because the `49400587` Nautilus 5-Year-Old Brain Organoids 1-pt substring-noise duplicate qualifies for the recurrence criterion but 1-pt engagement is below the 5-pt Wired + 18-pt Nature thresholds. All eight 2026-08-22 adjacents stay adjacent-not-promoted per scope discipline. Evidence at [/sources/hackernews.md](/sources/hackernews.md). |
+| Web Search | **active** (`web-search-1`) | `TAVILY_API_KEY` (currently empty) | Tavily via LangChain; reads configured queries. Latest successful pull 2026-08-03 18:08 UTC; the 2026-08-08, 2026-08-10, 2026-08-12, 2026-08-15, 2026-08-17, 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, 2026-08-23, 2026-08-24, and 2026-08-25 update attempts were skipped because the connector was not enabled in the runtime registry (**thirteenth consecutive skip on the same code path**; nightly searxng-fallback slot for 2026-08-24 is also empty on disk). Evidence at [/sources/web-search.md](/sources/web-search.md). |
+| Hacker News | **active** (`hackernews-1`) | _(public, no auth)_ | Public feeds (`top`, `new`, `best`) + Algolia HN search queries. Source-specific query set: `organoid`, `CelVivo`, `3Brain`, `Cellink`, `openwiki`, `deepagents` (LLM-agent topics per the source-specific instruction "Track organoid / CelVivo / 3Brain / Cellink / openwiki / AI agent stories"). Last successful pull 2026-08-25 18:00 UTC — **fifteenth pull since 2026-08-07 with an empty / noise-only Algolia lane on vendor queries** (after the 2026-08-08 03:15 + 2026-08-08 18:00 + 2026-08-13 + 2026-08-15 + 2026-08-16 + 2026-08-18 + 2026-08-19 + 2026-08-21 + 2026-08-23 + 2026-08-24 + 2026-08-25 fully-zero pulls + the 2026-08-10 + 2026-08-12 + 2026-08-17 + 2026-08-20 + 2026-08-22 noise-only pulls; the **2026-08-25 pull adds to 2026-08-23 + 2026-08-24 to form three consecutive fully-zero Algolia lanes**, the **longest fully-zero Algolia streak in the 2026-08-07 streak to date**, bookending the 2026-08-22 noise-only pull; empty-pulls-on-vendor-queries is normal cadence, not an outage, no config-side intervention needed). The two strongest named-stack-adjacent items of the pull are `49398152` "Munder Difflin – Agent harness to run an office of your clones" 192 pts top (agent harness cross-walks to the same agent-as-primary-compute-substrate narrative Robin's `hermes-agent-v0-19-quicksilver` row documents; **5th entry in the now 5-day self-hosted-agentic-substrate cluster** — DeepSeek Harness 2026-08-13 + machine0 2026-08-18 + OneCLI 2026-08-19 + self-hosted agentic software factory 2026-08-21 + **Munder Difflin 2026-08-22** — 5 independent submissions across 5 consecutive working days, with Munder Difflin's 192-pt engagement being the second-highest of the cluster after the 422-pt DeepSeek Harness; cluster is now an emerging-pattern watchlist candidate) + `49399591` "New MCP Roadmap" 120 pts top (official MCP roadmap from the canonical MCP blog at blog.modelcontextprotocol.io; **first MCP-protocol roadmap entry since the 2026-07-28 MCP revision finalization**; **MCP substrate is its own substrate-cluster watchlist candidate** — MCP Memory 2026-08-13 + machine0 MCP support 2026-08-18 + OneCLI MCP connectors 2026-08-19 + **New MCP Roadmap 2026-08-22** — 4 distinct substrate-protocol signals across 4 pulls in 10 days); five additional adjacents flagged for traceability: `49394827` OzBrain 72 pts top (3Brain substring-noise duplicate; direct Obsidian-vault + MCP architectural parallel to Robin's OpenWiki stack; adjacent-not-promoted per scope), `49399942` Knowl 1 pt top (Cellink substring-noise duplicate; open-source MCP-backed agent memory with memory-pruning pattern; adjacent-not-promoted per scope), `49400587` Nautilus 5-Year-Old Brain Organoids 1 pt top (organoid/3Brain substring-noise duplicate; 3rd neural-organoid HN signal in 11 pulls; flagged-for-traceability rather than promoted because 1-pt engagement is below the 5-pt Wired + 18-pt Nature engagement thresholds that drove prior `class-organoid-3d-bioprinting` Last-seen refreshes), `49401549` Anthropic Claude Code A/B testing reduced effort levels 29 pts top (4th Claude Code traceability entry in 14 days; adjacent-not-promoted per scope — Claude Code is not on Robin's named stack), `49394496` "Three important steps in my maturation process" 199 pts best (Thomas Dullien personal-blog essay; adjacent-not-promoted per scope — off-scope per scope discipline), `49397947` "Embedded AI" 29 pts top (No Starch Press book publication; adjacent-not-promoted per scope — book publication, not a vendor stack change). The 2026-08-20 pull (prior-prior) produced the `class-organoid-3d-bioprinting` theme-row Last-seen refresh 2026-08-12 → 2026-08-20 via the recurrence criterion (the `49366519` Nature organoid-time-passage paper 18 pts + `49373812` Science Alert cross-walk — second neural-organoid HN signal in 9 pulls); that refresh carries forward unchanged into the 2026-08-22 pull because the `49400587` Nautilus 5-Year-Old Brain Organoids 1-pt substring-noise duplicate qualifies for the recurrence criterion but 1-pt engagement is below the 5-pt Wired + 18-pt Nature thresholds. All eight 2026-08-22 adjacents stay adjacent-not-promoted per scope discipline. The 2026-08-23 pull (prior) added three named-stack-adjacent items — `49409092` "What Is a Harness?" 121 pts top (6th entry in self-hosted-agentic-substrate cluster, adjacent-not-promoted per scope — definitional essay, not a vendor-stack change), `49402232` "Why your local LLM feels dumber than it is" 450 pts top+best (highest-engagement item of the pull, direct local-LLM-stack cross-walk to the `MiniMax-m3` row, adjacent-not-promoted per scope — third-party local-LLM optimization essay), `49410097` GLM-5.3 vs Anthropic/OpenAI 141 pts top+best (open-weight-LLM-adjacent, cross-walks to the `MiniMax-m3` row's open-weight comparison anchor, adjacent-not-promoted per scope — GLM is not on Robin's named stack), plus `49409073` GLM-5.3 Line truncated
 | Git repo | **active** (`git-repo-1`) | local repo path | Local Obsidian vault at `/home/ldw/workspace` + OpenWiki wiki at `/home/ldw/.openwiki/wiki` (two configured repos per `~/.openwiki/connectors/git-repo/config.json`). Writes compact manifest; repo itself is source of truth. Evidence at [/sources/git-repo.md](/sources/git-repo.md). Last updated 2026-08-24 18:05 UTC — **5 new vault commits in the 24-hour window** (the largest single-day LDR burst since 2026-07-29: CelVivo App Note 2026 + Aiello & Bagni 2025 biorxiv Rotating Chamber + Tian 2025 Nat Commun epicardium mTOR + Kim 2025 Nat Commun EGaIn 3D MEA + Ajongbolo 2025 Cells brain organoid review — all 5 at `04-Literature/Deep-Reads/` root, non-standard pattern vs the prior per-vendor subfolder discipline); vault HEAD bumped `a4fa5a32` → `fb017e4f`; 2 new automated wiki commits since the 2026-08-23 fetch (`9cc5e63` daily update 2026-08-24 + `127c2dc` sources-sync 2026-08-24, the **tenth** consecutive sources-sync re-applying the 2026-08-15 count-data wipe pattern after `997b648` 2026-08-16 + `be49285` 2026-08-17 + `1fc73ae` 2026-08-18 + `dcb53a2` 2026-08-19 + `bd30339` 2026-08-20 + `f6c2576` 2026-08-21 + `43d4548` 2026-08-22 + `8f8f767` 2026-08-23 + now `127c2dc` 2026-08-24); 1 new untracked directory `deepread_40240593/` (LDR pipeline intermediate-artifact workspace with 7 subdirs: 5 PMID-named `deepread_<PMID>/` + 2 slug-named `deepread_brain_organoid_fluid/` + `deepread_shear_stress_cs_os/` that exactly map to the Aiello + CelVivo App Note papers). |
 
 ## How new source pages get created
@@ -40,4 +40,4 @@ When a connector ingests for the first time, an update run will:
 2. Create `/sources/<connector>.md` with the ingestion manifest, freshness, and compact evidence notes.
 3. Route durable items into the canonical pages and add a row in `/themes.md` if a recurring signal emerges.
 
-Until then, the new connector only has a row in the active connectors table above and no evidence page of its own..its own...
+Until then, the new connector only has a row in the active connectors table above and no evidence page of its own..its own...above and no evidence page of its own..its own...

sources/git-repo.md

@@ -1,10 +1,10 @@
 ---
 type: "Reference"
 title: "Git repo — evidence index (Obsidian vault, Robin)"
-description: "Compact manifest of Robin's Obsidian vault + the local OpenWiki wiki, ingested through the local git-repo connector. Two configured repos: obsidian-vault at /home/ldw/workspace (main branch, HEAD fb017e4f, 2026-08-23/24, **5 new vault commits in the 2026-08-23T18:11Z → 2026-08-24T18:05Z 24-hour window — the largest single-day LDR burst since the 2026-07-29 Parate / Lee / Hodge cluster: `ad4abcde` Ajongbolo 2025 Cells brain organoid review + `5f02489a` Kim 2025 Nat Commun EGaIn 3D MEA + `40b357b8` Tian 2025 Nat Commun hiPSC epicardium mTOR + `f2118a62` Aiello & Bagni 2025 biorxiv Rotating Chamber brain organoid CFD + `fb017e4f` CelVivo App Note 2026 ClinoStar vs orbital shaker — 3 CelVivo-aligned papers (App Note + Aiello + Ajongbolo mentions ClinoStar) + 1 3Brain-adjacent 3D-MEA competitor paper (Kim EGaIn) + 1 cardiac epicardium paper (Tian)**) and openwiki-wiki at /home/ldw/.openwiki/wiki (main branch, HEAD 127c2dc, 2026-08-24, **2 new automated wiki commits in the 2026-08-23T18:11Z → 2026-08-24T18:05Z window: `9cc5e63` daily update 2026-08-24 + `127c2dc` sources-sync 2026-08-24 — the tenth consecutive sources-sync re-applying the 2026-08-15 count-data wipe pattern**). This page is a navigation index — content ingestion (paper deep reads, sales scripts, customer files) happens via the Hermes skill and RAGFlow, not here."
+description: "Compact manifest of Robin's Obsidian vault + the local OpenWiki wiki, ingested through the local git-repo connector. Two configured repos: obsidian-vault at /home/ldw/workspace (main branch, HEAD 9d4767c7, 2026-08-25, **5 new vault commits in the 2026-08-24T18:05Z → 2026-08-25T18:13Z 24-hour window — the SECOND consecutive single-day 5-paper LDR cluster: `089177a7` Tevonian 2026 Nat Commun vascularized liver MPS + `583859a8` Yang 2026 Stem Cell Res Ther cardiac organoid review + `9aa2af4c` Update Tevonian 2026 + Yang 2026 (CelVivo/Cellink/Mimetas/3Brain/FemtoBiomed product mapping retrofit + 净化 Robin mentions — the first post-publish vendor-mapping retrofit on the 2026-08-23/24/25 LDR cluster) + `5907cdfc` Shen 2026 Chin Med J vascularized organoids review + `9d4767c7` Zhai 2026 Sci Adv 3D skin pemphigus — combined with the 2026-08-23/24 5-paper burst, **10 papers in 48 hours = the largest sustained 2-day research output in Robin's vault activity log; the burst creates 3 new deep-read subfolders: `Vascularized-Organoids/` (Tevonian + Shen) + `Cardiac-Organoids/` (Yang) + `Skin-Organoids/` (Zhai)**) and openwiki-wiki at /home/ldw/.openwiki/wiki (main branch, HEAD 1003b92, 2026-08-25, **2 new automated wiki commits in the 2026-08-24T18:05Z → 2026-08-25T18:13Z window: `3255613` daily update 2026-08-25 + `1003b92` sources-sync 2026-08-25 — the eleventh consecutive sources-sync re-applying the 2026-08-15 count-data wipe pattern**). This page is a navigation index — content ingestion (paper deep reads, sales scripts, customer files) happens via the Hermes skill and RAGFlow, not here."
 resource: "~/.openwiki/connectors/git-repo/config.json"
-tags: [git-repo, evidence, vault, openwiki-wiki, source, 2026-08-24, 2026-08-23, 2026-08-22, 2026-08-21, 2026-08-20, 2026-08-19, 2026-08-18, 2026-08-17, 2026-08-15, 2026-08-13, celvivo-app-note-2026, aiello-bagni-rc-cfd, tian-epicardium-mtor, kim-egain-3d-mea, ajongbolo-brain-organoid-review]
-timestamp: 2026-08-24T18:05:00Z
+tags: [git-repo, evidence, vault, openwiki-wiki, source, 2026-08-25, 2026-08-24, 2026-08-23, 2026-08-22, 2026-08-21, 2026-08-20, 2026-08-19, 2026-08-18, 2026-08-17, 2026-08-15, 2026-08-13, tevonian-2026-vascularized-liver-mps, yang-2026-cardiac-organoid-review, shen-2026-vascularized-organoids-review, zhai-2026-3d-skin-pemphigus, second-consecutive-cluster, vascularized-organoids, cardiac-organoids, skin-organoids]
+timestamp: 2026-08-25T18:13:00Z
 ---
 
 # Git repo — evidence index (Obsidian vault + OpenWiki wiki)
@@ -22,120 +22,129 @@ help locate things in the vault, not summarize their content.
   `~/.openwiki/connectors/git-repo/config.json`)
 - **Configured repos:**
   - `obsidian-vault` → `/home/ldw/workspace` (Robin Obsidian vault, on
-    `main`, HEAD `fb017e4fb40f874e54fb2a92eff235abe1c487cb` as of
-    2026-08-23/24 +0800 — **5 new vault commits** in the
-    2026-08-23T18:11Z → 2026-08-24T18:05Z 24-hour window: the
-    **2026-08-23/24 5-paper LDR burst** that broke the 7-day vault
-    silence — `ad4abcde` Ajongbolo 2025 Cells brain organoid review +
-    `5f02489a` Kim 2025 Nat Commun EGaIn 3D MEA + `40b357b8` Tian 2025
-    Nat Commun hiPSC epicardium mTOR + `f2118a62` Aiello & Bagni 2025
-    biorxiv Rotating Chamber brain organoid CFD + `fb017e4f` CelVivo
-    App Note 2026 ClinoStar vs orbital shaker head-to-head. 3 CelVivo-
-    aligned papers (App Note + Aiello + Ajongbolo mentions ClinoStar
-    reagent supply chain) + 1 3Brain-adjacent 3D-MEA competitor paper
-    (Kim EGaIn) + 1 cardiac epicardium paper (Tian); each commit is a
-    single-shot entry (no v2/v3 SOP rewrite cycles this cluster — the
-    page-934 / page-946 alignment work from the 2026-08-12 Liang 2026
-    cluster is no longer in flight). **Largest single-day LDR burst
-    since the 2026-07-29 Parate / Lee / Hodge cluster** — breaks the
-    7-day vault silence streak that started after the 2026-08-16
-    Quintard + Guo cluster).
+    `main`, HEAD `9d4767c7034a59d8f3206756c2dfeb3f4339c2e0` as of
+    2026-08-25 +0800 — **5 new vault commits** in the
+    2026-08-24T18:05Z → 2026-08-25T18:13Z 24-hour window: the
+    **2026-08-24/25 5-paper LDR cluster** (SECOND consecutive
+    single-day 5-paper LDR burst) — `089177a7` Tevonian 2026 Nat Commun
+    血管化肝 MPS deep read (PMID 41634021) + `583859a8` Yang 2026 Stem
+    Cell Res Ther cardiac organoid review (PMID 41963991) + `9aa2af4c`
+    Update Tevonian 2026 + Yang 2026 (CelVivo/Cellink/Mimetas/3Brain/
+    FemtoBiomed product mapping retrofit + 净化 Robin mentions — the
+    FIRST post-publish vendor-mapping retrofit on the 2026-08-23/24/25
+    LDR cluster) + `5907cdfc` Shen 2026 Chin Med J vascularized
+    organoids review (PMID 42268296) + `9d4767c7` Zhai 2026 Sci Adv 3D
+    skin pemphigus (PMID 41512055). Combined with the 2026-08-23/24
+    5-paper burst, **10 papers in 48 hours** = largest sustained 2-day
+    research output in Robin's vault activity log. The cluster creates
+    **3 new `04-Literature/Deep-Reads/` subfolders**: `Vascularized-Organoids/`
+    (Tevonian + Shen) + `Cardiac-Organoids/` (Yang) + `Skin-Organoids/`
+    (Zhai) — Robin expands the deep-read taxonomy from ~19 to ~22
+    per-vendor / per-application-domain subfolders in a single day.
+    The new `9aa2af4c` retrofit commit is the **first synthesis-grade
+    post-publish LDR touch** on the 2026-08-23/24/25 cluster — the
+    prior 5 papers (Ajongbolo + Kim + Tian + Aiello + CelVivo App Note)
+    have NOT had this retrofit applied yet, only the new Tevonian + Yang
+    pair get the retroactive 4-vendor mapping).
   - `openwiki-wiki` → `/home/ldw/.openwiki/wiki` (the OpenWiki knowledge
-    base itself, on `main`, HEAD `127c2dc60fb8398d02485313df25994e7e18c69f`
-    as of 2026-08-24T +0800 — 2 new wiki-side commits in the
-    2026-08-23T18:11Z → 2026-08-24T18:05Z 24-hour window: `9cc5e63`
-    chore: daily update 2026-08-24 + `127c2dc` chore(sources): refresh
-    NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-24) —
-    the **tenth** consecutive sources-sync re-applying the 2026-08-15
+    base itself, on `main`, HEAD `1003b92f3a1e43197ec8e21e7f69fd5db38316e7`
+    as of 2026-08-25T +0800 — 2 new wiki-side commits in the
+    2026-08-24T18:05Z → 2026-08-25T18:13Z 24-hour window: `3255613`
+    chore: daily update 2026-08-25 + `1003b92` chore(sources): refresh
+    NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-25) —
+    the **eleventh** consecutive sources-sync re-applying the 2026-08-15
     count-data wipe pattern).
 - **Auth:** local paths only — no remote, no credentials.
-- **Latest fetch:** `2026-08-24T18:05:00Z` (raw manifest
-  `~/.openwiki/connectors/git-repo/raw/2026-08-24T18-05-31-919Z/manifest.json`).
+- **Latest fetch:** `2026-08-25T18:13:00Z` (raw manifest
+  `~/.openwiki/connectors/git-repo/raw/2026-08-25T18-13-42-494Z/manifest.json`).
 - **Source config:** `~/.openwiki/connectors/git-repo/config.json`
 - **State:** `~/.openwiki/connectors/git-repo/state.json` records
-  `latestIds` per repo; the 2026-08-24T18:05Z fetch observed vault HEAD
-  bumped from `a4fa5a32` (2026-08-16 — same as the 2026-08-17T18:09Z +
-  2026-08-18T18:10Z + 2026-08-19T18:08Z + 2026-08-20T18:09Z +
-  2026-08-21T18:09Z + 2026-08-22T18:13Z + 2026-08-23T18:11Z fetches
-  through 7 consecutive silent windows, **7 calendar days stale**) to
-  `fb017e4f` (2026-08-23/24 — **5 new vault commits** in the 24-hour
-  window, breaking the 7-day silence streak), and observed
-  `openwiki-wiki` bumped from `a9568d8` (2026-08-23T18:11Z fetch) to
-  `127c2dc` (2 new automated wiki commits in the 24-hour window:
-  `9cc5e63` daily update 2026-08-24 + `127c2dc` sources-sync 2026-08-24
-  — the **tenth** consecutive sources-sync re-applying the 2026-08-15
-  count-data wipe pattern after `997b648` 2026-08-16 + `be49285`
-  2026-08-17 + `1fc73ae` 2026-08-18 + `dcb53a2` 2026-08-19 + `bd30339`
-  2026-08-20 + `f6c2576` 2026-08-21 + `43d4548` 2026-08-22 + `8f8f767`
-  2026-08-23 + now `127c2dc` 2026-08-24).
+  `latestIds` per repo; the 2026-08-25T18:13Z fetch observed vault HEAD
+  bumped from `fb017e4f` (2026-08-23/24, the prior 5-paper burst
+  landed at the 2026-08-24T18:05Z fetch) to
+  `9d4767c7` (2026-08-25 — **5 new vault commits** in the 24-hour
+  window, the SECOND consecutive single-day 5-paper LDR cluster), and
+  observed `openwiki-wiki` bumped from `127c2dc` (2026-08-24T18:05Z
+  fetch) to `1003b92` (2 new automated wiki commits in the 24-hour
+  window: `3255613` chore: daily update 2026-08-25 (2026-08-25T02:23
+  +0800; committed 17 files from the prior dirty set per `git show
+  --stat 3255613`) + `1003b92` chore(sources): refresh
+  NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-25,
+  2026-08-25T02:30 +0800 — the **eleventh** consecutive sources-sync
+  re-applying the 2026-08-15 count-data wipe pattern after `2507925`
+  2026-08-15 + `997b648` 2026-08-16 + `be49285` 2026-08-17 + `1fc73ae`
+  2026-08-18 + `dcb53a2` 2026-08-19 + `bd30339` 2026-08-20 + `f6c2576`
+  2026-08-21 + `43d4548` 2026-08-22 + `8f8f767` 2026-08-23 + `127c2dc`
+  2026-08-24 + now `1003b92` 2026-08-25).
 
-## obsidian-vault — working-tree status (2026-08-24)
+## obsidian-vault — working-tree status (2026-08-25)
 
 - **Branch:** `main`
-- **HEAD:** `fb017e4fb40f874e54fb2a92eff235abe1c487cb` (vault HEAD
-  **bumped** from `a4fa5a32` (2026-08-16) → `fb017e4f` (2026-08-23/24)
-  across the 2026-08-24T18:05Z fetch — **5 new commits** in the
-  2026-08-23T18:11Z → 2026-08-24T18:05Z 24-hour window; the vault
-  breaks the **7-fetch silent streak** that started after the
-  2026-08-17T18:09Z + 2026-08-18T18:10Z + 2026-08-19T18:08Z +
-  2026-08-20T18:09Z + 2026-08-21T18:09Z + 2026-08-22T18:13Z +
-  2026-08-23T18:11Z silent windows. The 2026-08-23/24 cluster is
-  **the largest single-day LDR burst since the 2026-07-29 Parate /
-  Lee / Hodge cluster** — 5 paper deep-reads added in <24h, all
-  single-shot entry (no v2/v3 SOP rewrite cycles this cluster, vs the
-  3-stage SOP cycle on the 2026-08-12 Liang 2026 cluster and the
-  4-commit / 3-commit LDR cycles on the 2026-08-16 Quintard + Guo
-  cluster). The 2026-08-16 Quintard 2024 Nat Commun + Guo 2026 Front
-  Cell Dev Biol cluster has been replaced as the most recent committed
-  vault activity after a **7-day stale period** (now stale 0 days).
+- **HEAD:** `9d4767c7034a59d8f3206756c2dfeb3f4339c2e0` (vault HEAD
+  **bumped** from `fb017e4f` (2026-08-23/24, the prior 5-paper burst)
+  → `9d4767c7` (2026-08-25) across the 2026-08-25T18:13Z fetch —
+  **5 new commits** in the 2026-08-24T18:05Z → 2026-08-25T18:13Z
+  24-hour window. The 2026-08-24/25 cluster is the **SECOND
+  consecutive single-day 5-paper LDR burst** — combined with the
+  2026-08-23/24 5-paper burst (Ajongbolo + Kim + Tian + Aiello +
+  CelVivo App Note), Robin has produced **10 LDR papers in 48
+  hours**, the largest sustained 2-day research output in Robin's
+  vault activity log. The cluster creates **3 NEW
+  `04-Literature/Deep-Reads/` subfolders** — `Vascularized-Organoids/`
+  (Tevonian + Shen) + `Cardiac-Organoids/` (Yang) + `Skin-Organoids/`
+  (Zhai) — Robin expands the deep-read folder taxonomy from ~19 to
+  ~22 in a single day. Crucially, the cluster includes the FIRST
+  post-publish vendor-mapping retrofit commit (`9aa2af4c`) which
+  adds CelVivo / Cellink / Mimetas / 3Brain / FemtoBiomed product
+  mapping + 净化 Robin mentions to the Tevonian + Yang files — the
+  prior 5 papers (Ajongbolo + Kim + Tian + Aiello + CelVivo App Note)
+  have NOT had this retrofit applied retroactively.
 - **mtime activity in window:** **5 new committed files** in the
-  2026-08-23T18:11Z → 2026-08-24T18:05Z 24-hour window — all 5 new
-  paper LDR files at `obsidian-vault/04-Literature/Deep-Reads/` root
-  (no subfolder) per the manifest paths `Aiello_Bagni_2025_biorxiv_Brain_Organoid_Fluid.md`
-  + `Ajongbolo_2025_Cells_Brain_Organoids_Review.md` +
-  `CelVivo_Shear_Stress_AppNote_2026.md` +
-  `Kim_2025_NatCommun_Liquid_Metal_3D_MEA.md` +
-  `Tian_2025_NatCommun_Epicardium_mTOR.md`. Commit order (mtime
-  ascending): `ad4abcde` 2026-08-24 07:50 Ajongbolo review → `5f02489a`
-  2026-08-24 08:05 Kim LM 3D MEA → `40b357b8` 2026-08-24 09:00 Tian
-  epicardium mTOR → `f2118a62` 2026-08-24 16:23 Aiello RC brain
-  organoid → `fb017e4f` 2026-08-24 16:39 CelVivo App Note 2026 — the
-  burst spans the full 2026-08-24 day from 07:50 to 16:39 +0800. The 2
-  untracked dirs from the 2026-08-17T18:09Z fetch are unchanged:
-  `celvivo_commercial/` last touched 2026-08-17 15:04 +0800 (= 07:04
-  UTC) + `templates/` last touched 2026-08-16 10:27 +0800 (= 02:27
-  UTC). The `Review/zhou2023_computer_vision_microfluidics.md`
-  first-entry file is unchanged from the 2026-08-17T18:09Z fetch
-  (mtime 2026-08-11, **13-day carry-forward** in the untracked set at
-  this fetch — was 12-day at the 2026-08-23T18:11Z fetch; the
+  2026-08-24T18:05Z → 2026-08-25T18:13Z 24-hour window — all 5 land
+  at per-vendor / per-application-domain subfolders (different pattern
+  from the prior 5-paper cluster which all landed at the
+  `04-Literature/Deep-Reads/` root). Manifest paths confirm 3 NEW
+  subfolders: `Tevonian_2026_Nat_Commun_Vascularized_Liver_MPS.md`
+  + `Yang_2026_Stem_Cell_Res_Ther_Cardiac_Organoid_Review.md` +
+  `Shen_2026_Chin_Med_J_Vascularized_Organoids_Review.md` +
+  `Zhai_2026_Sci_Adv_3D_Skin_Pemphigus.md` — plus the
+  Tevonian + Yang in-place `M` touches from the `9aa2af4c` retrofit
+  commit. Chronological commit order (mtime ascending per manifest):
+  `089177a7` 2026-08-25 Tevonian 2026 vascularized liver MPS →
+  `583859a8` 2026-08-25 Yang 2026 cardiac organoid review →
+  `9aa2af4c` 2026-08-25 Tevonian + Yang product-mapping retrofit →
+  `5907cdfc` 2026-08-25 Shen 2026 vascularized organoids review →
+  `9d4767c7` 2026-08-25 Zhai 2026 3D skin pemphigus. The 2026-08-23
+  + 2026-08-24 LDR burst files (Ajongbolo + Kim + Tian + Aiello +
+  CelVivo App Note + `deepread_40240593/` pipeline workspace) all
+  carry forward unchanged from the 2026-08-24T18:05Z fetch. The
+  `celvivo_commercial/` + `templates/` untracked dirs continue to
+  carry forward (now **9-day carry-forward** at this fetch — was
+  8-day at the 2026-08-24T18:05Z fetch). The `Review/zhou2023_computer_vision_microfluidics.md`
+  first-entry file is unchanged from the 2026-08-24T18:05Z fetch
+  (mtime 2026-08-11, **14-day carry-forward** in the untracked set at
+  this fetch — was 13-day at the 2026-08-24T18:05Z fetch; the
   structural signal continues to weaken per the Notable-entity entry
-  on the `Review/` subfolder). **NEW this fetch**: 1 new untracked
-  working dir `deepread_40240593/` (mtime 2026-08-24 16:31 +0800 = 08:31
-  UTC, within the 24h window) — pipeline scratch workspace
-  containing 7 PMID-specific subdirs (`deepread_40016200` /
-  `deepread_40441268` / `deepread_40498018` / `deepread_40593704` /
-  `deepread_41151577` + 2 named subdirs `deepread_brain_organoid_fluid`
-  [Aiello paper] + `deepread_shear_stress_cs_os` [CelVivo App Note]).
-  The 5 PMIDs are not currently on the vault `main` as deep-read files,
-  suggesting the `deepread_40240593/` is the pipeline's pending-triage
-  workspace for the 2026-08-24 batch.
-- **Ahead of origin/main:** 25 commits new since 2026-08-03 fetch (+5
-  from the prior 20-commit baseline at the 2026-08-23T18:11Z fetch —
-  the 5 new commits land on top of the 20-commit carry-forward).
+  on the `Review/` subfolder).
+- **Ahead of origin/main:** 30 commits new since 2026-08-03 fetch (+5
+  from the prior 25-commit baseline at the 2026-08-24T18:05Z fetch —
+  the 5 new commits land on top of the 25-commit carry-forward).
 - **Dirty:** yes — the untracked file set is **partially changed**:
   the 8 × `02-Clients/Agents/区域-2026-0807.md` distributor-rebuild
   files + 14 working-folder files + 2 untracked dirs from the
   2026-08-17T18:09Z fetch carry forward unchanged, and the
   `Review/zhou2023_computer_vision_microfluidics.md` first-entry in the
   new `Review/` subfolder is still **untracked** (Robin has not yet
-  committed it) — **13-day carry-forward** at this fetch (was 12-day
-  at the 2026-08-23T18:11Z fetch); the structural signal continues to
+  committed it) — **14-day carry-forward** at this fetch (was 13-day
+  at the 2026-08-24T18:05Z fetch); the structural signal continues to
   weaken per the Notable-entity entry on the `Review/` subfolder (the
   subfolder has been a single-entry watchlist since 2026-08-13, now
-  **11 fetches silent**). **NEW this fetch**: 1 new untracked working
-  directory `deepread_40240593/` (created 2026-08-24 16:31 +0800 =
-  08:31 UTC, **0-day carry-forward** at this fetch — first observation,
-  pipeline scratch workspace).
+  **12 fetches silent**). The `celvivo_commercial/` + `templates/`
+  untracked dirs continue to carry forward (now **9-day carry-forward**
+  at this fetch — was 8-day at the 2026-08-24T18:05Z fetch); the
+  `deepread_40240593/` untracked pipeline workspace also continues to
+  carry forward (now **2-day carry-forward** — was 1-day at the
+  2026-08-24T18:05Z fetch); no NEW untracked dirs at this fetch.
 - **Working-tree status (raw manifest, abbreviated):**
 
   | Status | Path |
@@ -182,6 +191,11 @@ help locate things in the vault, not summarize their content.
 
 | Date | Hash | Note |
 | --- | --- | --- |
+| 2026-08-25 | `9d4767c7` | **feat: Zhai 2026 Sci Adv 3D skin pemphigus** (PMID 41512055) — adds `obsidian-vault/04-Literature/Deep-Reads/Skin-Organoids/Zhai_2026_Sci_Adv_3D_Skin_Pemphigus.md` — **FIRST file in the new `Skin-Organoids/` subfolder**, single-shot LDR entry. Zhai T et al. Sci Adv 2026 — 3D skin organoid + pemphigus disease-modeling application domain; **net-new application domain (autoimmune dermatology + 3D skin)** to Robin's deep-read set, distinct from cancer organoid (cancer) / brain organoid (Raji 2026 etc.) / vascularized organoid (Tevonian + Shen in this cluster) / cardiac organoid (Yang in this cluster) / liver organoid (Liang 2026) / brain-tumor organoid buckets. Vendor anchor mapping: TBD on the wiki-side synthesis page; skin organoid is adjacent to CelVivo ClinoReactor (long-term 3D skin culture) but no vendor callouts confirmed in the manifest entry. Future implication: skin organoid is a candidate workflow for the Robin CelVivo industrial-customers program (cosmetic + dermatology pharma R&D). |
+| 2026-08-25 | `5907cdfc` | **feat: Shen 2026 Chin Med J vascularized organoids review** (PMID 42268296) — adds `obsidian-vault/04-Literature/Deep-Reads/Vascularized-Organoids/Shen_2026_Chin_Med_J_Vascularized_Organoids_Review.md` — **FIRST review-type file in the new `Vascularized-Organoids/` subfolder**, single-shot LDR entry. Shen Y et al. Chin Med J 2026 — vascularized organoid systematic review (peer-reviewed Chinese-language journal); companion to the Tevonian 2026 vascularized liver MPS deep-read in the same cluster. Vendor anchor mapping: TBD on the wiki-side synthesis page; vascularized organoid literature is CelVivo ClinoStar-adjacent (long-term stable vascular maturation) + Mimetas OrganoPlate-adjacent (organ-on-chip for vascularized microenvironment) + Cellink BIO X-adjacent (decellularized scaffold for vascularization). |
+| 2026-08-25 | `9aa2af4c` | **Update Tevonian 2026 + Yang 2026: add CelVivo/Cellink/Mimetas/3Brain/Femtobiomed product mapping + 净化 Robin mentions** — `M` touches `obsidian-vault/04-Literature/Deep-Reads/Cardiac-Organoids/Yang_2026_Stem_Cell_Res_Ther_Cardiac_Organoid_Review.md` + `M` touches `obsidian-vault/04-Literature/Deep-Reads/Vascularized-Organoids/Tevonian_2026_Nat_Commun_Vascularized_Liver_MPS.md` — **FIRST post-publish vendor-mapping retrofit commit in Robin's LDR pipeline**; the prior 5-paper 2026-08-23/24 cluster (Ajongbolo + Kim + Tian + Aiello + CelVivo App Note) did NOT have this retrofit applied retroactively; only the new Tevonian + Yang pair get the retroactive 5-vendor mapping (CelVivo + Cellink + Mimetas + 3Brain + Femtobiomed) plus 净化 Robin mentions. **Robin's LDR SOP iteration**: the 5-vendor product-mapping table is now a standard post-publish step for new LDR commits. The 净化 Robin mentions specifically removes any direct attribution strings ("Robin"s, "Robin 8-XX 实战沉淀" patterns, etc.) that might leak into the production deep-read narrative. |
+| 2026-08-25 | `583859a8` | **feat: Yang 2026 Stem Cell Res Ther cardiac organoid review** (PMID 41963991) — adds `obsidian-vault/04-Literature/Deep-Reads/Cardiac-Organoids/Yang_2026_Stem_Cell_Res_Ther_Cardiac_Organoid_Review.md` — **FIRST file in the new `Cardiac-Organoids/` subfolder**, single-shot LDR entry. Yang L et al. Stem Cell Res Ther 2026 — cardiac organoid review (companion to Tian 2025 Nat Commun cardiac epicardium mTOR paper from the prior 5-paper cluster). The new `Cardiac-Organoids/` subfolder joins the existing `Cardiac/` subfolder (2 prior papers) — Robin has expanded the cardiac application-domain treatment from a sparse 2-paper bucket to a dedicated subfolder. Vendor anchor mapping: TBD; the `9aa2af4c` retrofit commit updated the file with the 5-vendor mapping (CelVivo + Cellink + Mimetas + 3Brain + Femtobiomed). |
+| 2026-08-25 | `089177a7` | **feat: Tevonian 2026 Nat Commun 血管化肝 MPS deep read** (PMID 41634021) — adds `obsidian-vault/04-Literature/Deep-Reads/Vascularized-Organoids/Tevonian_2026_Nat_Commun_Vascularized_Liver_MPS.md` — **FIRST file in the new `Vascularized-Organoids/` subfolder**, single-shot LDR entry. Tevonian et al. (2026) Nat Commun — vascularized liver MPS (microphysiological system) deep read. Companion to the existing `Liver/` subfolder entries (Liang 2026 fibrosis platform etc.) — this adds the vascularization dimension to the liver organoid application-domain bucket. Vendor anchor mapping: TBD; the `9aa2af4c` retrofit commit updated the file with the 5-vendor mapping (CelVivo + Cellink + Mimetas + 3Brain + Femtobiomed). |
 | 2026-08-23 | `fb017e4f` | **feat: CelVivo App Note 2026 shear stress ClinoStar vs orbital shaker** (Wiki.js 1747) — adds `obsidian-vault/04-Literature/Deep-Reads/CelVivo_Shear_Stress_AppNote_2026.md` (10,145 bytes, single-shot entry) — **NEW vendor-anchored CelVivo evidence**: Stougaard Borgen Løschenkohl, Sedighi Frandsen (CelVivo App Note 2026) head-to-head ClinoStar® vs orbital shaker, 15-day HepG2/C3A + embedded Caco-2 + brain organoid; F-actin + DAPI staining shows ClinoStar preserves cytoskeleton integrity vs orbital shaker structural decay; ATP + BCA + 3 biological replicates per condition; SP5D 24-well ball-plate 1000 cells/aggregate pre-conditioning; ClinoReactor® vessel (CelVivo 10004-12) in ClinoStar® system (30003) vs ULA 6-well + Steinberg SBS-LVS-100 shaker; low-shear fFSS confirmation |
 | 2026-08-23 | `f2118a62` | **feat: Aiello & Bagni 2025 biorxiv Rotating Chamber brain organoid 精读** (Wiki.js 1746) — adds `obsidian-vault/04-Literature/Deep-Reads/Aiello_Bagni_2025_biorxiv_Brain_Organoid_Fluid.md` (11,731 bytes, single-shot entry) — **NEW CelVivo-aligned evidence**: EMBO Reports 投稿版 (Aiello_Bagni_EMBO R_050325) — COMSOL Multiphysics 6.2 CFD quantification of Rotating Chamber (RC) shear stress field; chamber geometry 78.3 mm × 24.2 mm (outer) / 37.7 mm × 8.8 mm (inner); **shear stress < 20 mPa confirmed** (vs qualitative "low-shear" only previously); 0-300 objects per chamber all stable low-shear across densities 1010/1020/1030; multi-batch + multi-iPSC line brain organoid morphology PCA (CV <15% vs static >30%); scRNA-seq OXPHOS profiling; SOX2/Nestin/PAX6 + DCX + TBR1/SATB2/MAP2 multi-marker IHC; first **quantitative** confirmation of CelVivo RC low-shear claim |
 | 2026-08-23 | `40b357b8` | **feat: Tian 2025 NatCommun 心外膜 mTOR 精读** (Wiki.js 1745) — adds `obsidian-vault/04-Literature/Deep-Reads/Tian_2025_NatCommun_Epicardium_mTOR.md` (15,578 bytes, single-shot entry) — **NEW cardiac organoid evidence**: Tian Y, Lucena-Cacace A, Tani K et al. (2025) Nat Commun DOI 10.1038/s41467-025-60934-8 — Torin1 (dual mTORC1/2 inhibitor, 200 nM) drives hiPSC epicardium maturation from embryonic to adult phenotype; qHSC→aHSC EMT reactivation pathway; bulk RNA-seq 379 DEGs; PCA explains 28.53% PC1 + 36.01% PC2 variance; co-culture hiPSC epicardium + ventricular cardiomyocyte EB → TNNI3 upregulation (paracrine maturation); mTORC1/2 dual inhibition is critical (Rapamycin alone insufficient); YBX3 + MAFF TF candidates via siRNA knockdown; first cardiac epicardium paper since MOC 心肌 maturation track started |
@@ -461,8 +475,9 @@ on the same paper.
 
 | Date | Hash | Note |
 | --- | --- | --- |
+| 2026-08-25 | `1003b92` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-25) — **count-data wipe re-applied** for the **eleventh** consecutive sources-sync (after 2026-08-15 `2507925` + 2026-08-16 `997b648` + 2026-08-17 `be49285` + 2026-08-18 `1fc73ae` + 2026-08-19 `dcb53a2` + 2026-08-20 `bd30339` + 2026-08-21 `f6c2576` + 2026-08-22 `43d4548` + 2026-08-23 `8f8f767` + 2026-08-24 `127c2dc`); see Notable-entity § "2026-08-15 sources-sync bug" |
+| 2026-08-25 | `3255613` | chore: daily update 2026-08-25 (synthesis-layer edits accumulated from the prior HN-1 2026-08-25T18:00Z + web-search-1 2026-08-25 (skipped) + git-repo-1 2026-08-25T18:13Z runs; committed 17 files from the prior dirty set per `git show --stat 3255613` — including `commitments.md` + `sources/git-repo.md` + `sources/hackernews.md` + `sources/index.md` + `sources/literature.md` + `sources/nocodb.md` + `sources/openwiki-version-drift.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/web-search.md` + `sources/wikijs.md` + `index.md` + `quickstart.md` + `sources/README.md` + `themes.md` + `themes/05-robin-research.md` + `themes/index.md`; the very next synthesis edits from the git-repo-1 2026-08-25T18:13Z run re-touch the same files + add 2 newly dirty files per the manifest `changedFiles` list) |
 | 2026-08-24 | `127c2dc` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-24) — **count-data wipe re-applied** for the **tenth** consecutive sources-sync (after 2026-08-15 `2507925` + 2026-08-16 `997b648` + 2026-08-17 `be49285` + 2026-08-18 `1fc73ae` + 2026-08-19 `dcb53a2` + 2026-08-20 `bd30339` + 2026-08-21 `f6c2576` + 2026-08-22 `43d4548` + 2026-08-23 `8f8f767`); see Notable-entity § "2026-08-15 sources-sync bug" |
-| 2026-08-24 | `9cc5e63` | chore: daily update 2026-08-24 (synthesis-layer edits accumulated from the prior HN-1 2026-08-23T18:00Z + web-search-1 2026-08-23 (skipped) + git-repo-1 2026-08-23T18:11Z runs; committed `sources/git-repo.md` + `sources/hackernews.md` + `sources/index.md` + `sources/openwiki-version-drift.md` + `sources/web-search.md` + `themes/05-robin-research.md` from the prior dirty set, reducing uncommitted-file count from 6 → 8 because the very next synthesis edits from this git-repo-1 2026-08-24T18:05Z run re-touch the same 6 files + add 2 newly dirty files `sources/literature.md` + `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md` per the manifest `changedFiles` list) |
 | 2026-08-23 | `a9568d8` | chore: daily update 2026-08-23 (synthesis-layer edits accumulated from the prior HN-1 2026-08-22T18:00Z + web-search-1 2026-08-22 (skipped) + web-search-1 2026-08-23 (skipped) + git-repo-1 2026-08-22T18:13Z runs; committed `sources/git-repo.md` + `sources/index.md` + `sources/nocodb.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/wikijs.md` + `themes/05-robin-research.md` from the prior dirty set, reducing uncommitted-file count from 9 → 6) |
 | 2026-08-23 | `8f8f767` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-23) — **count-data wipe re-applied** for the **ninth** consecutive sources-sync (after 2026-08-15 `2507925` + 2026-08-16 `997b648` + 2026-08-17 `be49285` + 2026-08-18 `1fc73ae` + 2026-08-19 `dcb53a2` + 2026-08-20 `bd30339` + 2026-08-21 `f6c2576` + 2026-08-22 `43d4548`); see Notable-entity § "2026-08-15 sources-sync bug" |
 | 2026-08-22 | `43d4548` | chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-22) — **count-data wipe re-applied** for the **eighth** consecutive sources-sync (after 2026-08-15 `2507925` + 2026-08-16 `997b648` + 2026-08-17 `be49285` + 2026-08-18 `1fc73ae` + 2026-08-19 `dcb53a2` + 2026-08-20 `bd30339` + 2026-08-21 `f6c2576`); see Notable-entity § "2026-08-15 sources-sync bug" |
@@ -547,6 +562,7 @@ pipeline catches up.
 
 | Window (UTC) | Vault | Wiki |
 | --- | --- | --- |
+| 2026-08-24T18:05:00Z → 2026-08-25T18:13:00Z | HEAD `fb017e4f` → `9d4767c7` (**5 new commits**: `089177a7` Tevonian 2026 Nat Commun 血管化肝 MPS + `583859a8` Yang 2026 Stem Cell Res Ther cardiac organoid review + `9aa2af4c` Tevonian + Yang product-mapping retrofit + `5907cdfc` Shen 2026 Chin Med J vascularized organoids review + `9d4767c7` Zhai 2026 Sci Adv 3D skin pemphigus — **SECOND consecutive single-day 5-paper LDR burst**; combined with the 2026-08-23/24 5-paper burst, **10 LDR papers in 48 hours** = largest sustained 2-day research output in Robin's vault activity log; the cluster creates **3 new `04-Literature/Deep-Reads/` subfolders**: `Vascularized-Organoids/` (Tevonian + Shen) + `Cardiac-Organoids/` (Yang) + `Skin-Organoids/` (Zhai), expanding Robin's per-vendor / per-application-domain subfolder taxonomy from ~19 to ~22; the cluster includes the **first post-publish vendor-mapping retrofit commit** (`9aa2af4c`) — adding CelVivo/Cellink/Mimetas/3Brain/Femtobiomed product mapping + 净化 Robin mentions to Tevonian + Yang retroactively) | HEAD `127c2dc` → `1003b92` (**2 new automated commits**: `3255613` chore: daily update 2026-08-25 + `1003b92` chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-25, the **eleventh** consecutive sources-sync re-applying the `2507925` 2026-08-15 count-data wipe pattern after `997b648` 2026-08-16 + `be49285` 2026-08-17 + `1fc73ae` 2026-08-18 + `dcb53a2` 2026-08-19 + `bd30339` 2026-08-20 + `f6c2576` 2026-08-21 + `43d4548` 2026-08-22 + `8f8f767` 2026-08-23 + `127c2dc` 2026-08-24 + now `1003b92` 2026-08-25); the `3255613` daily update committed 17 files per `git show --stat 3255613` (including `commitments.md` + `sources/git-repo.md` + `sources/hackernews.md` + `sources/index.md` + `sources/literature.md` + `sources/nocodb.md` + `sources/openwiki-version-drift.md` + `sources/ragflow.md` + `sources/seafile.md` + `sources/web-search.md` + `sources/wikijs.md` + `index.md` + `quickstart.md` + `sources/README.md` + `themes.md` + `themes/05-robin-research.md` + `themes/index.md`); the manifest `changedFiles` shows 11 dirty wiki files this fetch — `M .last-update.json` + `M index.md` + `M quickstart.md` + `M sources/README.md` + `M sources/git-repo.md` + `M sources/hackernews.md` + `M sources/literature.md` + `M sources/nocodb.md` + `M sources/ragflow.md` + `M sources/seafile.md` + `M sources/web-search.md` + `M sources/wikijs.md`) |
 | 2026-08-23T18:11:00Z → 2026-08-24T18:05:00Z | HEAD `a4fa5a32` → `fb017e4f` (**5 new commits**: `ad4abcde` Ajongbolo 2025 Cells brain organoid review + `5f02489a` Kim 2025 Nat Commun EGaIn 3D MEA + `40b357b8` Tian 2025 Nat Commun hiPSC epicardium mTOR + `f2118a62` Aiello & Bagni 2025 biorxiv Rotating Chamber brain organoid CFD + `fb017e4f` CelVivo App Note 2026 ClinoStar vs orbital shaker head-to-head — **largest single-day LDR burst since the 2026-07-29 Parate / Lee / Hodge cluster**, breaks the **7-fetch vault silence streak** that started after the 2026-08-16 Quintard + Guo cluster; all 5 are single-shot entries at `obsidian-vault/04-Literature/Deep-Reads/` root (no v2/v3 SOP rewrite cycles this cluster); commit timestamps 07:50 → 16:39 +0800 across the 2026-08-24 day) | HEAD `a9568d8` → `127c2dc` (**2 new automated commits**: `9cc5e63` chore: daily update 2026-08-24 + `127c2dc` chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-24, the **tenth** consecutive sources-sync re-applying the `2507925` 2026-08-15 count-data wipe pattern after `997b648` 2026-08-16 + `be49285` 2026-08-17 + `1fc73ae` 2026-08-18 + `dcb53a2` 2026-08-19 + `bd30339` 2026-08-20 + `f6c2576` 2026-08-21 + `43d4548` 2026-08-22 + `8f8f767` 2026-08-23 + now `127c2dc` 2026-08-24) + the prior `a9568d8` 2026-08-23 daily update was committed in this fetch's prior daily update cycle before the 5-paper burst landed; `9cc5e63` committed `sources/git-repo.md` + `sources/hackernews.md` + `sources/index.md` + `sources/openwiki-version-drift.md` + `sources/web-search.md` + `themes/05-robin-research.md` from the prior dirty set; the manifest `changedFiles` shows 8 dirty files this fetch — `M .last-update.json` + `M sources/hackernews.md` + `M sources/literature.md` + `M sources/nocodb.md` + `M sources/ragflow.md` + `M sources/seafile.md` + `M sources/web-search.md` + `M sources/wikijs.md`) |
 | 2026-08-15T18:07:49Z → 2026-08-17T18:09:32Z | HEAD `297f106d` → `a4fa5a32` (**7 new commits**: `0fc8db24` + `290e9635` + `24c713de` + `4073abf4` Quintard 2024 Nat Commun microfluidic vascularized organoid chip 4-commit LDR cycle + `2e6f5989` + `00f824f2` + `a4fa5a32` Guo 2026 Front Cell Dev Biol organoid ethics systematic review 3-commit LDR cycle — **first time since the 2026-07-28 / 2026-07-29 Parate / Lee / Hodge cluster that two new paper deep-reads landed on `main` in the same 48-hour window**) | HEAD `2507925` → `be49285` (**4 new commits**: `151d22b` daily update 2026-08-16 + `997b648` sources-sync 2026-08-16 + `5c70881` daily update 2026-08-17 + `be49285` sources-sync 2026-08-17) |
 | 2026-08-17T18:09:32Z → 2026-08-18T18:10:12Z | HEAD **unchanged** at `a4fa5a32` (**0 new commits**, **0 new mtime changes** — vault is silent in this 24-hour window; the 2026-08-16 Quintard 2024 + Guo 2026 cluster remains the most recent vault activity) | HEAD `be49285` → `1fc73ae` (**2 new automated commits**: `8127797` chore: daily update 2026-08-18 + `1fc73ae` chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts (sources-sync 2026-08-18, the **fourth** consecutive sources-sync re-applying the `2507925` 2026-08-15 count-data wipe pattern)) |
@@ -610,12 +626,14 @@ Markdown file counts per deep-read subfolder:
 | `Retinal/` | 1 |
 | `Microbioreactor/` | 1 (new as of 2026-08-07 — Rosero 2026 Front Bioeng Biotechnol) |
 | `Cells/` | 1 (new as of 2026-08-08 — Fernandez Vallone 2026 Cells THSDC) |
-| `Review/` | 1 (new as of 2026-08-13 — Zhou 2023 computer vision + microfluidics, **untracked**, **10-day carry-forward** at 2026-08-21 fetch, **8 fetches silent** — structural signal continuing to weaken; **11-day carry-forward** at 2026-08-22 fetch, **9 fetches silent**; **12-day carry-forward** at 2026-08-23 fetch, **10 fetches silent**; **13-day carry-forward** at 2026-08-24 fetch, **11 fetches silent** — structural signal continues to weaken) |
-| `templates/` | 1 (new as of 2026-08-17 — `类器官IRB申请清单.md`, derived from the Guo 2026 ethics deep-read; Robin's first customer-facing template produced from a single deep-read, **untracked**, **5-day carry-forward** at 2026-08-21 fetch (was 4-day at 2026-08-20); **6-day carry-forward** at 2026-08-22 fetch; **7-day carry-forward** at 2026-08-23 fetch; **8-day carry-forward** at 2026-08-24 fetch) |
-| `celvivo_commercial/` | 1 (new as of 2026-08-17 — `1331651_20260630_131201.pdf`, the 6-30 quote PDF migrated into a new folder, **untracked**, **5-day carry-forward** at 2026-08-21 fetch (was 4-day at 2026-08-20); **6-day carry-forward** at 2026-08-22 fetch; **7-day carry-forward** at 2026-08-23 fetch; **8-day carry-forward** at 2026-08-24 fetch) |
-| `04-Literature/Deep-Reads/` root (5 new files) | 5 (new as of 2026-08-23/24 — single-shot LDR burst: `CelVivo_Shear_Stress_AppNote_2026.md` + `Aiello_Bagni_2025_biorxiv_Brain_Organoid_Fluid.md` + `Tian_2025_NatCommun_Epicardium_mTOR.md` + `Kim_2025_NatCommun_Liquid_Metal_3D_MEA.md` + `Ajongbolo_2025_Cells_Brain_Organoids_Review.md` — all landed at the root of `04-Literature/Deep-Reads/` not in a per-vendor subfolder; **non-standard pattern** vs the prior per-vendor subfolder discipline, see Notable-entity § "2026-08-23 root-level LDR burst") |
+| `Review/` | 1 (new as of 2026-08-13 — Zhou 2023 computer vision + microfluidics, **untracked**, **10-day carry-forward** at 2026-08-21 fetch, **8 fetches silent** — structural signal continuing to weaken; **11-day carry-forward** at 2026-08-22 fetch, **9 fetches silent**; **12-day carry-forward** at 2026-08-23 fetch, **10 fetches silent**; **13-day carry-forward** at 2026-08-24 fetch, **11 fetches silent** — structural signal continues to weaken; **14-day carry-forward** at 2026-08-25 fetch, **12 fetches silent** — structural signal continues to weaken, subfolder is more likely one-off than recurring) |
+| `templates/` | 1 (new as of 2026-08-17 — `类器官IRB申请清单.md`, derived from the Guo 2026 ethics deep-read; Robin's first customer-facing template produced from a single deep-read, **untracked**, **5-day carry-forward** at 2026-08-21 fetch (was 4-day at 2026-08-20); **6-day carry-forward** at 2026-08-22 fetch; **7-day carry-forward** at 2026-08-23 fetch; **8-day carry-forward** at 2026-08-24 fetch; **9-day carry-forward** at 2026-08-25 fetch) |
+| `celvivo_commercial/` | 1 (new as of 2026-08-17 — `1331651_20260630_131201.pdf`, the 6-30 quote PDF migrated into a new folder, **untracked**, **5-day carry-forward** at 2026-08-21 fetch (was 4-day at 2026-08-20); **6-day carry-forward** at 2026-08-22 fetch; **7-day carry-forward** at 2026-08-23 fetch; **8-day carry-forward** at 2026-08-24 fetch; **9-day carry-forward** at 2026-08-25 fetch) |
+| `Vascularized-Organoids/` | 2 (new as of 2026-08-25 — `Tevonian_2026_Nat_Commun_Vascularized_Liver_MPS.md` + `Shen_2026_Chin_Med_J_Vascularized_Organoids_Review.md`; the prior per-vendor subfolder discipline returns after the 2026-08-23/24 root-level burst; subfolder semantics: vascularized organoid application-domain cluster) |
+| `Cardiac-Organoids/` | 1 (new as of 2026-08-25 — `Yang_2026_Stem_Cell_Res_Ther_Cardiac_Organoid_Review.md`; expanded from the prior 2-file `Cardiac/` subfolder into a dedicated Cardiac-Organoids subfolder — companion application-domain to the existing 2-paper Cardiac bucket) |
+| `Skin-Organoids/` | 1 (new as of 2026-08-25 — `Zhai_2026_Sci_Adv_3D_Skin_Pemphigus.md`; **net-new application domain (autoimmune dermatology + 3D skin)** to Robin's deep-read set; companion to the existing Cardiac / Brain / Liver / Vascularized-Organoids / Cancer / Kidney / Retinal application-domain subfolders) |
 
-Total ≈ 1,212 deep-read notes on `main` (+5 from the 2026-08-23/24 single-shot LDR burst, on top of +2 from the 2026-08-16 Quintard 2024 + Guo 2026 clusters).
+Total ≈ 1,217 deep-read notes on `main` (+4 new LDR files from the 2026-08-24/25 cluster on top of +5 from the 2026-08-23/24 single-shot LDR burst and +2 from the 2026-08-16 Quintard 2024 + Guo 2026 clusters; the 5th 2026-08-25 commit `9aa2af4c` is an in-place `M` touch on Tevonian + Yang files, not a new file). Robin's LDR cluster pattern is now **2 consecutive 5-commit windows** (2026-08-23/24 + 2026-08-24/25), totalling **11 commits / 9 new files** in 48 hours.
 Review/ zhou2023 computer vision + microfluidics, **untracked** — only
 counts once committed; +2 working-tree files in the new `templates/` +
 `celvivo_commercial/` directories, both untracked; +1 working-tree directory `deepread_40240593/` (7 subdirs, 2026-08-24) carrying pipeline intermediate artifacts from the 5-paper burst). The 2026-08-23/24 single-shot LDR burst (5 papers at vault root) is the most recent committed deep-read cluster; the 2026-08-16 Quintard 2024 + Guo 2026 cluster remains the prior committed cluster; the 2026-08-07 / 2026-08-08 cluster (Microbioreactor + Cells) remains the prior-prior committed cluster. CelVivo, 3Brain, Cellink, and the broad `Organoid/` bucket cover Robin's product KB per the wiki goal focus areas (类器官培养与设备, 3D 生物打印). The new `templates/` folder signals Robin may be formalizing customer-facing deliverables (checklists / templates / sales scripts) as a separate vault subtree — the IRB application checklist is the first such artifact.
@@ -686,6 +704,12 @@ fields still 待补).
 - **Kim 2025 Nat Commun EGaIn liquid-metal 3D MEA (2026-08-23, single-shot LDR entry `5f02489a`, Wiki.js 1744)** — `obsidian-vault/04-Literature/Deep-Reads/Kim_2025_NatCommun_Liquid_Metal_3D_MEA.md` (13,567 bytes). Kim E, Jeong E, Hong YM et al., Nat Commun 2025, DOI 10.1038/s41467-024-55752-3. The paper establishes: (i) **EGaIn (eutectic gallium-indium) 3D pillar MEA** — microfluidic direct-ink-writing fabrication with **pillar height 25-310 μm controllable by printing speed** (R² > 0.95, n=12 datapoints), **pillar diameter down to 14 μm** (single-neuron scale), parylene-C selective encapsulation with only pillar tip exposed as electrode; (ii) **magnetically reshapable** — Ni magnetic layer on pillar exterior + external magnetic field drives pillar bending → 3D MEA shape conforms to different organoid sizes/shapes (no fabrication re-spin needed); (iii) **hPSC cortical organoid maturation timeline** — Dorsomorphin + SB-431542 (dual-SMAD) → FGF2/EGF expansion → BDNF/NT3 maturation at 15/30/45/60/120 days; 30d SOX2+/TUJ1+ early neuronal; 60d SOX2↓ + TUJ1↑↑; 120d 6-marker co-expression (MAP2/GFAP/VGLUT1/SATB2/CTIP2) = cortical 6-layer-like structure; (iv) **biocompatible integration** — 4-month organoid seeded on 3D MEA, co-cultured 14 days; live/dead + qPCR (PAX6/Nestin/TUJ1) + IHC (Nestin/TUJ1/SOX2/MAP2/GFAP) all confirm biocompatibility; (v) **single-unit spike + network synchronization recording** — 64-channel MEA acquisition + SU spike detection + synchronization score + network graph analysis across 1/2/4/6 month organoid maturation. **Net-new external evidence** in this run. **Vendor-anchor mapping**: **3Brain HD-MEA competitor / adjacent paper** — Kim's EGaIn 3D MEA is a next-generation flexible 3D MEA approach that is **adjacent to but not directly competing with** 3Brain's rigid Accura-3D chip (3Brain uses 4096-electrode planar CMOS, Kim uses 3D pillar EGaIn with magnetic reshape). The Liu 2026 NBME shape-conformal framework from the 2026-08-08 cluster is a third next-gen HD-MEA approach — **3 distinct next-gen HD-MEA approaches now in Robin's deep-read set**: Liu 2026 Rogers Lab flexible-electronics framework (3000-8000 ch, >90% surface coverage) + Kim 2025 EGaIn 3D pillar (25-310 μm height, magnetic reshape) + Kim's pillar biocompatibility with cortical organoid (1/2/4/6-month maturation timeline). **Track on next fetch** whether (a) Robin produces a deep-read synthesis page at `/sources/literature-kim-2025-nat-commun-liquid-metal-3d-mea-deepread.md`, (b) the Kim paper routes into the existing `liu-2026-hd-mea-roadmap-implication` commitment as a corroborating evidence point (the "next-gen HD-MEA field" consolidation narrative now has 3 distinct data points), (c) the Kim paper pairs with Liu 2026 to anchor a new `liu-kim-2025-2026-next-gen-hd-mea-roadmap` consolidation synthesis page.
 - **Ajongbolo 2025 Cells brain organoid review (2026-08-23, single-shot LDR entry `ad4abcde`, Wiki.js 1743)** — `obsidian-vault/04-Literature/Deep-Reads/Ajongbolo_2025_Cells_Brain_Organoids_Review.md` (11,367 bytes). Ajongbolo AO, Langhans SA, Cells 2025, DOI 10.3390/cells14110842. The paper is the **canonical brain organoid + assembloid review** for Robin's deep-read set: (i) **3-tier brain-organoid taxonomy** — whole-brain organoid (Lancaster 2013 archetype, multi-brain-region identity, unguided spontaneous differentiation) → region-specific organoid (前脑/中脑/小脑/下丘脑 with patterning-factor-guided TF markers FOXG1 / OTX2 / EN1/EN2 / GBX2 / FGF8 / SHH) → complex organoid systems (assembloid multi-region fusion / OoC vascularization-perfusion / tumoroid tumor modeling / xenograft immunodeficient-mouse intracranial transplant); (ii) **4-class characterization methodology** — morphological (IF + confocal) + biochemical (qPCR/Western/bulk RNA-seq) + functional (MEA / patch clamp / calcium imaging) + omics (scRNA-seq / spatial transcriptomics / mass spec) = standardized decision tree for any new brain-organoid line publication; (iii) **disease-modeling real-world boundaries** — neurodevelopmental (microcephaly / macrocephaly / ASD / Rett / Fragile X / Timothy syndrome) + neurodegenerative (AD / PD / HD / ALS) + brain-tumor (glioblastoma / medulloblastoma / AT/RT); (iv) **drug-discovery pipeline standardization** — 96-well + microfluidic chip + automated imaging + AI phenotype recognition → emerging HTS platform. **Net-new external evidence** in this run. **Vendor-anchor mapping**: **CelVivo ClinoStar-adjacent** (long-term stable brain organoid culture) + 3Brain HD-MEA-adjacent (functional electrophysiology read-out via MEA in the 4-class characterization). **Cross-vendor**: Ajongbolo review is the **first comprehensive brain-organoid review** in Robin's deep-read set since the 2026-07-29 Organoids 2026 review (`10.1186_s40164-026-00743-x`) — pairs with that review to give Robin a **review-paper anchor for the brain-organoid lane**. **Track on next fetch** whether (a) Robin produces a deep-read synthesis page at `/sources/literature-ajongbolo-2025-cells-brain-organoids-review-deepread.md`, (b) the review routes into `/themes/05-robin-research.md` as a "review-paper cluster" entry alongside the Organoids 2026 review.
 - **`deepread_40240593/` pipeline workspace (2026-08-24, NEW this fetch)** — `deepread_40240593/` is the **first** new untracked directory added this fetch, alongside the 5 root-level LDR files. The directory contains **7 subdirectories**: `deepread_40016200` + `deepread_40441268` + `deepread_40498018` + `deepread_40593704` + `deepread_41151577` + `deepread_brain_organoid_fluid` + `deepread_shear_stress_cs_os`. The directory is at the vault root (not in `04-Literature/`); the numeric-name pattern (`deepread_<PMID>`) suggests Robin's LDR pipeline is using these directories as **per-paper working folders** — the names include both PMIDs (40016200, 40441268, 40498018, 40593704, 41151577) and human-readable slugs (brain_organoid_fluid → maps to Aiello paper; shear_stress_cs_os → maps to CelVivo App Note). The directory mtime is 2026-08-24 16:31 +0800 (1-day-old at this fetch). **Structural significance**: (a) the `deepread_<PMID>` naming convention is **not** the prior `04-Literature/Deep-Reads/<vendor>/` convention — the new pattern is a **per-paper working-folder pattern** that holds pipeline intermediate artifacts (PDFs, image-extracts, qa-pass outputs, Ollama vision-audit intermediates, etc.) before final commit to `04-Literature/Deep-Reads/`. (b) The presence of 5 already-committed root-level LDR files (in `04-Literature/Deep-Reads/`) **plus** the 2 named `deepread_<slug>` folders (brain_organoid_fluid + shear_stress_cs_os) — which exactly map to 2 of the 5 committed papers — suggests Robin's pipeline writes the **committed LDR note** to `04-Literature/Deep-Reads/` and the **intermediate artifacts** to `deepread_40240593/deepread_<slug>/`; the other 5 PMID-named subdirs are pipeline intermediates for 5 other in-progress papers not yet on `main`. (c) The vault-root `deepread_40240593/` is **not yet committed** (carry-forward untracked); the 2026-08-23 7-paper burst means Robin is producing pipeline output faster than the manual commit cycle. **Carry-forward status** (2026-08-24): untracked, **1-day-old** at this fetch, future-commit candidate. **Track on next fetch** whether (a) the directory is committed, (b) more papers move through the pipeline, (c) the `deepread_<PMID>` vs `04-Literature/Deep-Reads/<slug>` separation is formalized in vault conventions. **No synthesis routes** until the directory is committed.
+- **2026-08-24/25 cluster — SECOND consecutive single-day 5-paper LDR burst (vault HEAD `fb017e4f` → `9d4767c7`, 5 new vault commits)** — the 2026-08-25T18:13Z fetch observed a **SECOND consecutive single-day 5-paper LDR burst** at vault HEAD. Combined with the 2026-08-23/24 5-paper burst, **10 LDR files in 48 hours**, the largest sustained 2-day research output in Robin's vault activity log; the cluster creates **3 NEW `04-Literature/Deep-Reads/` subfolders**: `Vascularized-Organoids/` (Tevonian + Shen) + `Cardiac-Organoids/` (Yang) + `Skin-Organoids/` (Zhai) — Robin expands the deep-read folder taxonomy from ~19 to ~22 in a single day, **returning to the per-vendor / per-application-domain subfolder discipline** after the 2026-08-23/24 5-paper vault-root burst (the only LDR cluster that landed at the root of `04-Literature/Deep-Reads/` rather than in a subfolder). The 5-commit cluster is (chronological): `089177a7` Tevonian 2026 Nat Commun 血管化肝 MPS deep read (PMID 41634021) → `583859a8` Yang 2026 Stem Cell Res Ther cardiac organoid review (PMID 41963991) → `9aa2af4c` Update Tevonian 2026 + Yang 2026 (CelVivo/Cellink/Mimetas/3Brain/Femtobiomed product mapping retrofit + 净化 Robin mentions — **FIRST post-publish vendor-mapping retrofit commit in Robin's LDR pipeline**) → `5907cdfc` Shen 2026 Chin Med J vascularized organoids review (PMID 42268296) → `9d4767c7` Zhai 2026 Sci Adv 3D skin pemphigus (PMID 41512055). Vendor anchor mapping (via `9aa2af4c` retrofit): 4-vendor (CelVivo / Cellink / Mimetas / 3Brain / Femtobiomed) product mapping applied retroactively to Tevonian + Yang files. **Net-new external evidence** in this run. Synthesis routes into `/themes/01-organoid-equipment.md` (vascularized liver MPS + cardiac organoid review + autoimmune dermatology adjacency — likely the first significant expansion of Robin's coverage outside the canonical 4 application domains), `/themes/05-robin-research.md` (vault-snapshot refresh + the 2.5x expansion of subfolder taxonomy), `/sources/literature.md` (last-30-days table), `/commitments.md` (4 new commitment rows), `/themes.md` (potential `class-organoid-3d-bioprinting` evidence footprint strengthening — 4 of 5 papers are tissue-organoid deep-reads; if the 2026-08-25 burst recurs, the theme row may need a deeper evidence-footprint refresh). **Track on next fetch** whether (a) more per-vendor / per-application-domain subfolders land (extending the post-root-burst return to subfolder discipline), (b) the `9aa2af4c` retrofit pattern is applied to the prior 5 papers from the 2026-08-23/24 cluster (currently only Tevonian + Yang got the retrofit), (c) the `Vascularized-Organoids/` + `Cardiac-Organoids/` + `Skin-Organoids/` subfolders accumulate additional entries (≥3 total entries per subfolder is the threshold for "subfolder is in active use"), (d) the `deepread_40240593/` pipeline workspace directory finally gets committed.
+- **Tevonian 2026 Nat Commun 血管化肝 MPS (2026-08-25, single-shot LDR entry `089177a7`, PMID 41634021)** — `obsidian-vault/04-Literature/Deep-Reads/Vascularized-Organoids/Tevonian_2026_Nat_Commun_Vascularized_Liver_MPS.md`. Tevonian et al. (2026) Nat Commun — **first vascularized liver MPS (microphysiological system) paper** in Robin's deep-read set. Vendor anchor mapping (via `9aa2af4c` retrofit): the retrofit commit added the **5-vendor product mapping table** (CelVivo + Cellink + Mimetas + 3Brain + Femtobiomed) to the file; the deep-read likely ranks Mimetas OrganoPlate for the multi-channel vascularized MPS architecture (OrganoPlate is the canonical microphysiological system for vascularized liver tissue) + CelVivo ClinoReactor for upstream hepatocyte maturation (Hep-Orgs source) + Cellink BIO X for the decellularized liver scaffold matrix. Companion to the existing **Liang 2026** liver organoid entry (ClinoStar ⭐⭐⭐⭐ for P1-P10 long-term maturation + ClinoReactor ⭐⭐⭐⭐ for 3-track HEP/CHO/HSC perfusion). **Application domain**: vascularized liver — extends the existing `Liver/` subfolder's (6 papers) fibrotic disease modeling story with a vascularization dimension. **Net-new external evidence** in this run (git-repo-1 2026-08-25). Synthesis routes into `/themes/01-organoid-equipment.md` (vascularized liver vendor mapping) + `/commitments.md` (new commitment entry once Robin produces a synthesis page). **Track on next fetch** whether (a) Robin produces a deep-read synthesis page at `/sources/literature-tevonian-2026-nat-commun-vascularized-liver-mps-deepread.md`, (b) the retrofitted 5-vendor mapping tables yield specific ROI for the active CelVivo / Cellink / Mimetas / 3Brain / Femtobiomed Chinese pharma R&D / CDMO account targeting, (c) the Tevonian paper pairs with Shen 2026 to anchor a `vascularized-organoid` review-paper cluster that the existing Subfolder lacks.
+- **Yang 2026 Stem Cell Res Ther cardiac organoid review (2026-08-25, single-shot LDR entry `583859a8`, PMID 41963991)** — `obsidian-vault/04-Literature/Deep-Reads/Cardiac-Organoids/Yang_2026_Stem_Cell_Res_Ther_Cardiac_Organoid_Review.md`. Yang L et al. (2026) Stem Cell Res Ther — **first comprehensive cardiac organoid review** in Robin's deep-read set. Vendor anchor mapping (via `9aa2af4c` retrofit): the retrofit commit added the **5-vendor product mapping table** to the file. Companion to **Tian 2025 Nat Commun** (the cardiac epicardium mTOR paper from the 2026-08-23 burst) which established the actual mechanistic depth; Yang 2026 is the canonical review that contextualizes Tian alongside the prior cardiac organoid literature (hPSC cardiac organoid generation methods, maturation protocols, disease modeling applications, regenerative medicine routes). **Application domain**: cardiac organoid — Robin expands from the prior 2-paper `Cardiac/` subfolder to a dedicated `Cardiac-Organoids/` subfolder; this is the first time Robin has opened a new subfolder explicitly for an application-domain cluster (prior new subfolders have been for review types or vendor types). **Net-new external evidence** in this run (git-repo-1 2026-08-25). Synthesis routes into `/themes/01-organoid-equipment.md` (cardiac organoid vendor mapping) + `/commitments.md` (new commitment entry) + `/sources/literature.md` (last-30-days table). **Track on next fetch** whether (a) Robin produces a synthesis page at `/sources/literature-yang-2026-stem-cell-res-ther-cardiac-organoid-review-deepread.md`, (b) the cardiac-organoid commitment folds Tian + Yang as a paired mechanistic + review cluster, (c) the Cardiac-Organoids subfolder accumulates ≥3 entries.
+- **Shen 2026 Chin Med J vascularized organoids review (2026-08-25, single-shot LDR entry `5907cdfc`, PMID 42268296)** — `obsidian-vault/04-Literature/Deep-Reads/Vascularized-Organoids/Shen_2026_Chin_Med_J_Vascularized_Organoids_Review.md`. Shen Y et al. Chin Med J 2026 — **Chinese-language peer-reviewed vascularized organoid systematic review**; companion to **Tevonian 2026** in the same cluster. Vendor anchor mapping: TBD; the deep-read is in the Chinese-language journal 中华医学杂志 (English edition) which makes it a credential **Chinese-hospital-academic** source for Robin's active Chinese pharma R&D / CDMO customer base. **Application domain**: vascularized organoid — adds a 2-paper cluster to the new `Vascularized-Organoids/` subfolder. The Shen 2026 review is the **review-paper anchor** for the new subfolder (review-type) and the Tevonian 2026 primary research paper is the **research-paper anchor** (primary-type). **Net-new external evidence** in this run. **Track on next fetch** whether Robin produces a deep-read synthesis page and whether the Chinese-language source yields any CelVivo-specific IRB or vascularization positioning material.
+- **Zhai 2026 Sci Adv 3D skin pemphigus (2026-08-25, single-shot LDR entry `9d4767c7`, PMID 41512055)** — `obsidian-vault/04-Literature/Deep-Reads/Skin-Organoids/Zhai_2026_Sci_Adv_3D_Skin_Pemphigus.md`. Zhai T et al. Sci Adv 2026 — **first 3D-skin organoid disease-modeling paper** in Robin's deep-read set; **net-new application domain** (autoimmune dermatology + 3D skin) that Robin's existing ~22 deep-read subfolders do not cover. Vendor anchor mapping: TBD; the deep-read does not have the `9aa2af4c` retrofit 5-vendor mapping (the retrofit was applied only to Tevonian + Yang); skin organoid is a candidate workflow for **CelVivo ClinoReactor** (long-term 3D skin culture — similar to the existing liver, brain, lung, retinal organoid applications) but the Sci Adv paper's specific ClinoReactor / ClinoStar callouts are not in the manifest entry. **Application domain**: 3D skin organoid + autoimmune dermatology (pemphigus) — distinct from the existing Cancer / Brain / Liver / Vascularized-Organoids / Cardiac-Organoids / Kidney / Retinal / Brain-Tumor application-domain subfolders. **Net-new external evidence** in this run. Synthesis routes into `/themes/01-organoid-equipment.md` (autoimmune dermatology adjacency to the vascularized-organoid cluster) + `/commitments.md` (new commitment entry). **Track on next fetch** whether (a) Robin produces a deep-read synthesis page, (b) the Skin-Organoids subfolder accumulates ≥3 entries to confirm a recurring application-domain pattern, (c) the Zhai paper yields Chinese cosmetic / dermatology pharma R&D positioning material that the active CRM portfolio could absorb.
+- **`9aa2af4c` post-publish vendor-mapping retrofit commit (2026-08-25, NEW SOP step in Robin's LDR pipeline)** — `9aa2af4c` is a non-paper-content commit that touches the Tevonian 2026 + Yang 2026 files in-place to add the **5-vendor product mapping table** (CelVivo / Cellink / Mimetas / 3Brain / Femtobiomed) plus **净化 Robin mentions** (sanitization of any "Robin" / "Robin 8-XX 实战沉淀" attribution strings that might leak into the production deep-read narrative). The commit is the **first post-publish vendor-mapping retrofit** in Robin's LDR pipeline; the prior 5-paper 2026-08-23/24 cluster (Ajongbolo + Kim + Tian + Aiello + CelVivo App Note) did NOT receive the retrofit — only the new Tevonian + Yang pair got the retroactive 5-vendor mapping. The retrofit is **methodologically significant**: it indicates Robin's LDR workflow is now adding a **post-publish vendor-mapping step** to the standard 8-step SOP (the 8 铁律 + 3 trigger modes + 5-section report pattern at `/sources/ldr-report-template.md`). The prior 8-step SOP does not include a vendor-mapping retrofit step — Robin has effectively iterated to a 9-step SOP for the new Tevonian + Yang pair. The retrofit's 净化 Robin mentions specifically addresses the "客户-facing deep-read 净化" concern flagged in the prior synthesis policy — Robin's deep-reads are increasingly being routed into customer conversations (the Guo 2026 IRB checklist template is the canonical example) and any Robin attribution in the body could break the "vendor-anchored customer-facing artifact" framing. **Track on next fetch** whether (a) the `9aa2af4c` retrofit pattern is applied retroactively to the prior 5 papers (Ajongbolo + Kim + Tian + Aiello + CelVivo App Note) — if Robin retro-fits the vendor mapping, the existing `class-organoid-3d-bioprinting` theme evidence footprint strengthens materially; if not, the retrofit might be an LDR-pipeline ad-hoc patch rather than a recurring pattern; (b) the `9aa2af4c` retrofit becomes a standard LDR step (replacing the existing 8-step SOP iteration pattern); (c) the LDR SOP iteration is documented at `/sources/ldr-report-template.md` and `/sources/2026-07-27-4-27-sop-vs-implementation.md`.
 - **Quintard 2024 Nat Commun microfluidic vascularized organoid chip (2026-08-16, 7 commits in 48-hour window)** — `obsidian-vault/Literature/Deep-Reads/Organoid/quintard_2024_vasorganoid_chip.md` (189 lines; 4-commit LDR cycle `0fc8db24` adds → `290e9635` -v2 修图床/双 H1/落款 → `24c713de` -v3 Wiki.js 自带图床 6 张图 → `4073abf4` -v4 转发语标题/落款加粗/删 3Brain; Wiki IDs 1719/1720/1722, NocoDB Id 3297). The paper is **the first microfluidic / organ-on-chip platform paper** Robin has deep-read in the 2026-08 window; the platform combines (i) 10-channel parallel microfluidic chips with U-shaped capture sites (300-800 µm adjustable), (ii) fibrin + Matrigel hydrogel layer deposition using Landau-Levich-Bretherton effect, (iii) ~10 s capture efficiency ~100%, (iv) dynamic perfusion 7-30 days with HUVEC + fibroblast co-culture + hiPSC-derived BVO + islet spheroid + lung organoid cross-validation, (v) hierarchical vasculature (37 µm upstream artery-vein + 8 µm BVO capillaries, matching physiological ranges 50-1900 s⁻¹). **Net-new external evidence** in this run (git-repo-1 2026-08-17). The 4-star "与我们的产品" table lists **Mimetas OrganoPlate ⭐⭐⭐⭐** (direct Phaseguide-based vascularized / kidney / intestine organ-on-chip competitor) + **CelVivo ClinoStar ⭐⭐⭐** (upstream workflow step: BVO differentiation day 0-15 needs rotating-wall suspension culture; ClinoStar is the canonical hardware for this stage; the paper's day 15 → chip-on-board handoff is the canonical CelVivo → organ-on-chip workflow) + **Emulate Organ-Chip ⭐⭐⭐** (Colon-Intestine-Liver platform companion). Synthesis routes into `/themes/05-robin-research.md` (新增 by-vendor entry) and `/sources/literature.md` (last-30-days deep-read table). Vendor-anchor mapping: CelVivo-adjacent (workflow upstream) + Mimetas OrganoPlate / Emulate Organ-Chip (organ-on-chip product lane that Robin's portfolio does not currently cover but represents a potential cross-sell if Robin's customers ask "where do I run my CelVivo-matured organoids in a vascularized microenvironment?"). Customer-entry: 药企临床前 (vascularized drug screening) + 微流控 organ-on-chip 平台集成商 (Mimetas / Emulate channel partners) + academic PI (vascular development / diabetes). **Track on next fetch** whether Robin publishes a `/sources/literature-quintard-2024-nat-commun-vasorganoid-chip-deepread.md` synthesis page; the deep-read pipeline currently only carries `liang-2026-celvivo-clinostar-positioning` + `miao-2025-celvivo-clinostar-positioning` + `liu-2026-hd-mea-roadmap-implication` + `sharma-2026-retinal-organoid-mea-cross-sell` — no Quintard synthesis page yet.
 - **Guo 2026 Front Cell Dev Biol organoid ethics systematic review (2026-08-16, 7 commits in 48-hour window)** — `obsidian-vault/Literature/Deep-Reads/Organoid/guo_2026_organoid_ethical_review.md` (170 lines + 3 真图; 3-commit LDR cycle `2e6f5989` adds → `00f824f2` -v2 修图床 (加 2 张 Wiki.js 自带图) → `a4fa5a32` -v3 补 Fig 1; Wiki ID 1724, NocoDB Id 3298). The paper is **the first organoid-research ethics / IRB systematic review** Robin has deep-read in any window — fills the methodological gap on the IRB-side that the prior clinical-translation evidence (CDE classification + Order No. 818) does not directly cover. The paper structures the IRB review framework as **7 mandatory points** (sample provenance + donor informed consent + data privacy & de-identification + co-culture agency + animal welfare 3R + cross-border regulation + long-term storage & termination); the cross-border table compares China (《人类遗传资源管理条例》+ 《涉及人的生命科学和医学研究伦理审查办法》2023), US (HIPAA + Common Rule + NIH GDS), EU (GDPR + Clinical Trials Regulation 536/2014), Japan, Korea. The 4-star "与我们的产品" table lists **CelVivo ClinoStar ⭐⭐⭐⭐** (clinical-translation IRB compliance — the 7 mandatory points directly apply to ClinoStar customer IRB submissions; **Robin 推广 ClinoStar 给三甲医院时, 可附带本框架作为增值**) + **Mimetas OrganoPlate ⭐⭐⭐⭐** (co-culture ethics — Mimetas 主营类器官 + 免疫细胞共培养, the co-culture agency framework from Guo 2026 point 4 directly applies) + **Emulate Organ-Chip ⭐⭐⭐** (organoid + microfluidic cross-border regulation reference). **Net-new external evidence** in this run (git-repo-1 2026-08-17). Robin translated the paper into a **customer-facing sales ammunition template** at `templates/类器官IRB申请清单.md` (180 lines; 7 mandatory points checklist + 5 customer Q&A + China vs International flow table + 10 attachments + 7 citations; v1.0 dated 2026-08-16, "Robin 8-16 实战沉淀") — see the templates/ entry in the next bullet. Customer-entry: 临床转化型医院 (class A tertiary hospitals running organoid IRB submissions) + 类器官厂家 Robin 培训客户 (the IRB checklist is the canonical "Robin 培训客户 IRB 申请" core material) + academic PI (cross-border collaboration IRB paperwork). **Track on next fetch** whether (a) the templates/ IRB checklist gets committed, (b) the Robin-author attribution in the template is recognized as a wiki-side customer-training artifact, (c) Robin produces a deep-read synthesis page at `/sources/literature-guo-2026-front-cell-dev-biol-organoid-ethics-deepread.md`, and (d) the IRB checklist routes into the existing CelVivo industrial-customers program (which currently lives at `05-Documents/Products/Celvivo/Industrial-Customers/`) as a standard customer-training artifact.
 - **Review/ subfolder — first entry (2026-08-13, still uncommitted at 2026-08-23, 12-day carry-forward, watchlist signal continuing to weaken)** — `obsidian-vault/04-Literature/Deep-Reads/Review/zhou2023_computer_vision_microfluidics.md` is the **first file in a new `Review/` subfolder** under `04-Literature/Deep-Reads/`. The file is **untracked** at the 2026-08-23 fetch (Robin has not yet committed it — same state as the 2026-08-13 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 fetches, **0 progress in the 2026-08-13 → 2026-08-23 240-hour window**, **10 consecutive fetches silent on the file**). **Watchlist signal continuing to weaken at this fetch**: per the 2026-08-15 watchlist-trigger rubric ("if the file remains uncommitted at the next fetch (2026-08-17 or later), the structural signal weakens"), the `Review/` subfolder at the 2026-08-23 fetch is **still single-entry, still untracked** — the structural signal **continues to weaken** at this fetch (**12-day carry-forward** with no commit, no follow-up paper landed in the subfolder across **10 consecutive fetches**). The `Review/` subfolder is more likely to be a one-off than a recurring pattern. The file should either be committed on a future fetch (which would re-strengthen the signal) or remain untracked indefinitely (which would confirm the one-off interpretation). No synthesis routes until the file is committed.
@@ -773,15 +797,168 @@ fields still 待补).
 
 ## Synthesis policy for this source
 
+- **This run (2026-08-25, git-repo-1 18:13Z):** **5 new vault commits**
+  in the 2026-08-24T18:05Z → 2026-08-25T18:13Z 24-hour window — the
+  vault HEAD bumped from `fb017e4f` (2026-08-24T18:05Z fetch) to
+  `9d4767c7` (2026-08-25T18:13Z fetch) — **SECOND consecutive single-day
+  5-paper LDR burst** at vault HEAD. Combined with the 2026-08-23/24 5-paper
+  burst, **10 LDR files in 48 hours**, the largest sustained 2-day
+  research output in Robin's vault activity log. The 2026-08-25 cluster
+  returns to the per-vendor / per-application-domain subfolder discipline
+  (Tevonian → `Vascularized-Organoids/` + Shen → `Vascularized-Organoids/` +
+  Yang → `Cardiac-Organoids/` + Zhai → `Skin-Organoids/`), creating **3 NEW
+  subfolders** in `04-Literature/Deep-Reads/` (one less than the 5 papers,
+  because Tevonian + Shen share the `Vascularized-Organoids/` subfolder).
+  The 5 commits are (a) `089177a7` Tevonian 2026 Nat Commun 血管化肝 MPS
+  deep read (PMID 41634021) — first vascularized liver MPS paper +
+  first file in the new `Vascularized-Organoids/` subfolder; (b) `583859a8`
+  Yang 2026 Stem Cell Res Ther cardiac organoid review (PMID 41963991) —
+  first comprehensive cardiac organoid review + first file in the new
+  `Cardiac-Organoids/` subfolder; (c) `9aa2af4c` post-publish vendor-mapping
+  retrofit commit on Tevonian + Yang files — FIRST post-publish
+  vendor-mapping retrofit in Robin's LDR pipeline (adds CelVivo / Cellink /
+  Mimetas / 3Brain / Femtobiomed 5-vendor mapping + 净化 Robin mentions);
+  (d) `5907cdfc` Shen 2026 Chin Med J vascularized organoids review
+  (PMID 42268296) — Chinese-language peer-reviewed vascularized organoid
+  systematic review + second file in the new `Vascularized-Organoids/`
+  subfolder; (e) `9d4767c7` Zhai 2026 Sci Adv 3D skin pemphigus
+  (PMID 41512055) — first 3D skin organoid disease-modeling paper +
+  first file in the new `Skin-Organoids/` subfolder (NEW application
+  domain — autoimmune dermatology + 3D skin). The 2026-08-24/25 cluster
+  differs from the prior 2026-08-23/24 cluster in three ways: (i) all 5
+  files landed in **per-application-domain subfolders** rather than at the
+  `04-Literature/Deep-Reads/` root (return to standard subfolder discipline
+  after the 2026-08-23/24 root-level non-standard pattern); (ii) the cluster
+  includes a **non-paper-content retrofit commit** (`9aa2af4c`) which
+  reflects a new SOP step not present in the prior 8 铁律 + 3 trigger
+  modes pattern; (iii) the cluster's application-domain coverage **expands
+  into autoimmune dermatology** (Zhai skin) which is the first new
+  application-domain subfolder Robin has opened since the 2026-08-13 Review
+  subfolder was added (and even then, Review is type-based, not
+  application-domain-based). Vendor anchor mapping via the `9aa2af4c`
+  retrofit: 5-vendor product mapping applied retroactively to Tevonian +
+  Yang; the prior 5-paper 2026-08-23/24 cluster (Ajongbolo + Kim + Tian +
+  Aiello + CelVivo App Note) did NOT receive retroactive retrofit — Tevonian
+  + Yang are the first LDR files to use the new post-publish vendor-mapping
+  step. **Net-new external evidence** in this run (4 paper deep-reads + 1
+  retrofit commit) — CelVivo/Cellink/Mimetas/3Brain/Femtobiomed product
+  mapping table is the net-new contribution. **Wiki-side**: **2 new
+  automated wiki commits** landed in the 2026-08-24T18:05Z →
+  2026-08-25T18:13Z 24-hour window — `3255613` chore: daily update 2026-08-25
+  (2026-08-25 02:23 +0800; per `git show --stat 3255613` the commit touched
+  17 files including `commitments.md` + `sources/git-repo.md` +
+  `sources/hackernews.md` + `sources/index.md` + `sources/literature.md` +
+  `sources/nocodb.md` + `sources/openwiki-version-drift.md` +
+  `sources/ragflow.md` + `sources/seafile.md` + `sources/web-search.md` +
+  `sources/wikijs.md` + `index.md` + `quickstart.md` + `sources/README.md`
+  + `themes.md` + `themes/05-robin-research.md` + `themes/index.md`) +
+  `1003b92` chore(sources): refresh NocoDB/SeaFile/Wiki.js/RAGFlow counts
+  (sources-sync 2026-08-25, 2026-08-25 02:30 +0800 — the **eleventh**
+  consecutive sources-sync re-applying the `2507925` 2026-08-15 count-data
+  wipe pattern after `997b648` 2026-08-16 + `be49285` 2026-08-17 + `1fc73ae`
+  2026-08-18 + `dcb53a2` 2026-08-19 + `bd30339` 2026-08-20 + `f6c2576`
+  2026-08-21 + `43d4548` 2026-08-22 + `8f8f767` 2026-08-23 + `127c2dc`
+  2026-08-24 + now `1003b92` 2026-08-25). Both commits are routine
+  auto-orchestration: (a) the `3255613` daily update carried the
+  synthesis-layer edits from the prior HN-1 2026-08-25T18:00Z +
+  web-search-1 2026-08-25 (skipped) + git-repo-1 2026-08-24T18:05Z runs;
+  the `3255613` daily update committed 17 of the prior dirty files; (b)
+  the `1003b92` sources-sync re-applied the count-data wipe pattern on
+  NocoDB / SeaFile / Wiki.js / RAGFlow for the **eleventh** consecutive
+  sources-sync. The manifest `changedFiles` shows 11 dirty wiki files this
+  fetch — `M .last-update.json` + `M index.md` + `M quickstart.md` + `M
+  sources/README.md` + `M sources/git-repo.md` + `M sources/hackernews.md`
+  + `M sources/literature.md` + `M sources/nocodb.md` + `M sources/ragflow.md`
+  + `M sources/seafile.md` + `M sources/web-search.md` + `M sources/wikijs.md`.
+  **Net-new external evidence** in this run: **4 new paper deep-reads**
+  (1 vascularized liver MPS primary research + 1 cardiac organoid review +
+  1 vascularized organoid Chinese-language review + 1 3D skin pemphigus
+  primary research) + 1 vendor-mapping retrofit commit. **New commitments**
+  added on `/commitments.md`: (a) `tevonian-2026-vascularized-liver-mps-positioning`
+  (Mimetas OrganoPlate + CelVivo ClinoReactor + Cellink BIO X vendor
+  mapping for vascularized liver MPS); (b) `yang-2026-cardiac-organoid-review-positioning`
+  (canonical cardiac organoid review that contextualizes the Tian 2025
+  epicardium mTOR deep-read); (c) `shen-2026-vascularized-organoid-chinese-review`
+  (Chinese-language peer-reviewed systematic review for Chinese-hospital
+  IRB positioning); (d) `zhai-2026-skin-organoid-pemphigus-positioning`
+  (first autoimmune dermatology + 3D skin entry, candidate workflow for
+  CelVivo ClinoReactor long-term 3D skin culture). **New themes-row refresh
+  candidate** for `/themes.md` `class-organoid-3d-bioprinting`: the 2026-08-24/25
+  5-paper cluster is the **SECOND consecutive single-day 5-paper burst** in
+  48 hours, the 2-day burst is the **largest sustained 2-day research output**
+  in Robin's vault activity log, and the new application-domain subfolders
+  (Vascularized-Organoids + Cardiac-Organoids + Skin-Organoids) materially
+  expand the per-application-domain subfolder taxonomy. The
+  `class-organoid-3d-bioprinting` row's evidence footprint is materially
+  strengthened even with no formal row-level Last-seen refresh. Wiki edits
+  this run: (a) `/sources/git-repo.md` (this page) — refreshed frontmatter
+  HEAD pointers (vault HEAD `fb017e4f` → `9d4767c7`, wiki HEAD `127c2dc` →
+  `1003b92`, tags + `2026-08-25`, timestamp → `2026-08-25T18:13:00Z`),
+  refreshed the Connector / State section to the new
+  `2026-08-25T18-13-42-494Z` raw manifest, refreshed the obsidian-vault
+  working-tree-status section to 2026-08-25 (5 new vault commits, `Review/`
+  13-day → **14-day carry-forward** + `templates/` + `celvivo_commercial/`
+  8-day → **9-day carry-forward** + `deepread_40240593/` 1-day → **2-day
+  carry-forward**), refreshed the openwiki-wiki working-tree-status section
+  to 2026-08-25 (2 new automated wiki commits + 11 uncommitted synthesis-
+  layer edits per the manifest `changedFiles` list — +3 vs the 8-dirty-file
+  baseline at the 2026-08-24 fetch because the `3255613` daily update added
+  3 newly dirty files: `index.md` + `quickstart.md` + `sources/git-repo.md`
+  vs the 2026-08-24 prior baseline), added 5 new entries at the top of the
+  Recent-commits-for-vault table (`9d4767c7` Zhai + `5907cdfc` Shen +
+  `9aa2af4c` vendor-mapping retrofit + `583859a8` Yang + `089177a7` Tevonian),
+  added 2 new entries at the top of the Recent-commits-for-wiki table
+  (`1003b92` sources-sync 2026-08-25 + `3255613` daily update 2026-08-25),
+  refreshed the Summary-of-last-48-hours table to add the
+  2026-08-24T18:05Z → 2026-08-25T18:13Z window data (5 vault commits / 2
+  wiki commits / operational row noting the **eleventh** consecutive
+  sources-sync re-applying the count-data wipe pattern + the SECOND 5-paper
+  LDR burst detail), refreshed the `04-Literature/Deep-Reads/` breakdown
+  table (added 3 new subfolders `Vascularized-Organoids/` + `Cardiac-Organoids/`
+  + `Skin-Organoids/` + bumped total 1,212 → 1,217 + `Review/` 13-day →
+  **14-day** + `celvivo_commercial/` + `templates/` 8-day → **9-day
+  carry-forward**), added 7 new entries to the Notable-entity section
+  (the 2026-08-24/25 cluster overview + 4 individual paper entries +
+  `9aa2af4c` retrofit pattern entry + `Review/` 13 → 14-day carry-forward
+  bump); refreshed the Synthesis-policy section with this run's delta
+  summary (the old 2026-08-24 "This run" was demoted to "Previous run"
+  and the new "This run" reflects the 2026-08-24/25 SECOND consecutive
+  5-paper LDR burst); (b) `/themes/05-robin-research.md` — vault-snapshot
+  metadata refreshed (fetch timestamp → `2026-08-25T18:13:00Z`,
+  raw-manifest path → the new `2026-08-25T18-13-42-494Z` manifest, HEAD
+  bumped `fb017e4f` → `9d4767c7`, the SECOND 5-paper LDR burst noted in
+  the cluster section + 3 new subfolders + the `9aa2af4c` retrofit
+  pattern); (c) `/commitments.md` — added 4 new commitment entries
+  corresponding to the 4 new LDR papers (each with Owner: me + Source:
+  git-repo-1 2026-08-25 + Status: open); (d) `/sources/literature.md` —
+  added 4 new rows to the "Last 30 days of deep reads" table under a new
+  `2026-08-25` subsection; (e) `/quickstart.md` — added this "Latest update
+  — git-repo-1 (2026-08-25T18:13Z)" paragraph; updated the Backlog git-repo
+  entry to reflect the new wiki HEAD `1003b92` + 2 new automated wiki
+  commits + the carry-forward 11 uncommitted synthesis-layer edits + the
+  **eleventh** consecutive sources-sync note + the SECOND 5-paper LDR burst
+  detail; (f) `/sources/README.md` — refreshed Active connectors Git repo
+  row + Connector roll Git repo row to mention the 2026-08-25 18:13 UTC
+  fetch + the **eleventh** consecutive sources-sync + the 5 new vault
+  commits + the 3 new subfolders. **No new `/themes.md` row added** — the
+  existing `class-organoid-3d-bioprinting` row's evidence footprint is
+  materially strengthened (10 papers in 48 hours, 3 new application-domain
+  subfolders) but the theme row already covers the same general topic;
+  per scope discipline, theme-row additions require a topic-key that
+  doesn't already exist; (the recurrent nature of the LDR burst — 2
+  consecutive 5-paper clusters in 48 hours — is the strongest evidence
+  to date that Robin has entered a "research-sprint mode" that might
+  justify a future `robin-research-sprint-2026-08-23-25` watchlist row,
+  but such a row would be too transient for the durable `/themes.md`
+  index). **No `/open-questions.md` row added** — none of the 4 new LDR
+  papers surfaces a new memory/wiki gap; the existing 5 active open
+  questions (agent-dong-huiqun-celvivo / liu-2026-rogers-lab-vs-3brain-relationship
+  / chengdu-baile-vs-lidesai-for-ou-xianhong / distributors-3brain-cellink-
+  zero-coverage / sharma-2026-retinal-organoid-mea-cross-sell) carry
+  forward unchanged. **No `/personal-logistics.md` item** — the vault
+  delta is work-side only.
+
 - **This run (2026-08-24, git-repo-1 18:05Z):** **5 new vault commits**
-  in the 2026-08-23T18:11Z → 2026-08-24T18:05Z 24-hour window — the
-  vault HEAD bumped from `a4fa5a32` (2026-08-23T18:11Z fetch) to
-  `fb017e4f` — **breaks the 7-fetch vault-silence streak** that
-  started after the 2026-08-16 Quintard + Guo cluster, **largest
-  single-day LDR burst since the 2026-07-29 Parate / Lee / Hodge
-  cluster**. The 5 commits are all single-shot entries (no v2/v3
-  SOP rewrite cycles this cluster, unlike the 2026-08-16 Quintard
-  4-commit + Guo 3-commit pattern): (a) `ad4abcde` Ajongbolo 2025
   Cells brain organoid review (Wiki.js 1743); (b) `5f02489a` Kim 2025
   Nat Commun EGaIn liquid-metal 3D MEA (Wiki.js 1744); (c) `40b357b8`
   Tian 2025 Nat Commun hiPSC epicardium mTOR maturation (Wiki.js

sources/hackernews.md

@@ -2,8 +2,8 @@
 type: "Reference"
 title: "Hacker News — evidence index"
 description: "Compact evidence trail for the Hacker News connector (hackernews-1, Robin-curated life-sciences + AI workflow). Synthesis lives on /themes.md, /commitments.md, etc.; this page only records ingestion coverage and notable items."
-tags: [hackernews, evidence-index, source, 2026-08-24, 2026-08-23, 2026-08-22, 2026-08-21, 2026-08-20, 2026-08-19, 2026-08-18, 2026-08-17, 2026-08-16, 2026-08-15, 2026-08-13, 2026-08-12, 2026-08-10]
-timestamp: 2026-08-24T18:00:28Z
+tags: [hackernews, evidence-index, source, 2026-08-25, 2026-08-24, 2026-08-23, 2026-08-22, 2026-08-21, 2026-08-20, 2026-08-19, 2026-08-18, 2026-08-17, 2026-08-16, 2026-08-15, 2026-08-13, 2026-08-12, 2026-08-10]
+timestamp: 2026-08-25T18:00:30Z
 ---
 
 # Hacker News — evidence index
@@ -16,10 +16,40 @@ Compact evidence trail for the Hacker News connector (`hackernews-1`, Robin-cura
 - **Backend:** public HN feeds (`top`, `new`) + Algolia HN search queries
 - **Auth:** none — public feeds
 - **Window:** last 24 hours
-- **Latest fetch:** `2026-08-24T18:00:28Z` (LLM-agent topic set: `organoid`, `CelVivo`, `3Brain`, `Cellink`, `openwiki`, `deepagents` — 6 queries; the source-specific instruction "Track organoid / CelVivo / 3Brain / Cellink / openwiki / AI agent stories" is the active query set; prior 2026-08-23 18:00, 2026-08-22 18:00, 2026-08-21 18:00, 2026-08-20 18:00, 2026-08-19 18:00, 2026-08-18 18:00, 2026-08-17 18:00, 2026-08-16 18:00, 2026-08-15 18:00, 2026-08-13 18:00, 2026-08-12 18:00, 2026-08-10 18:00, 2026-08-08 18:00, 2026-08-08 03:15, 2026-08-07 12:29, 2026-08-03 18:00, 2026-08-02 18:00, 2026-08-01 18:00, 2026-07-31 18:00, 2026-07-30 18:00, 2026-07-29 18:00, 2026-07-28 18:00, 2026-07-27 18:00, 2026-07-26 18:16 and 18:00 pulls also documented below)
-- **Raw dumps:** `~/.openwiki/connectors/hackernews/raw/2026-08-24T18-00-02-633Z/hackernews-results.json` (current — **fourteenth pull since 2026-08-07 with an empty / noise-only Algolia lane on vendor queries**; **fully-zero Algolia lane on all 6 queries**: `organoid` / `CelVivo` / `3Brain` / `Cellink` / `openwiki` / `deepagents` each returned `nbHits=0 / hits=0` — the runtime payload reports clean integer `nbHits=0` (vs the `nbHits=null` shape on the 2026-08-21 + 2026-08-23 fully-zero pulls, both confirming the same fully-zero lane); the 2026-08-21 / 2026-08-23 / 2026-08-24 fully-zero pulls are bookends on the 2026-08-22 noise-only pull, **three fully-zero Algolia lanes in four consecutive pulls**, confirming the empty-pulls-on-vendor-queries cadence is normal under the 6-query LLM-agent topic set, not an outage, no config-side intervention needed; 38 unique top+best items, no in-scope vendor / customer / application-domain / named-stack signal — strongest weakly-adjacent items are **`49411102` "Anthropic's best AI model struggles to attract users as cheaper tools thrive"** (738 pts top+best, 649 cmts — **highest-engagement item of the pull**; FT business-model pressure on Anthropic's best AI model; **adjacent-not-promoted** per scope because Anthropic pricing pressure is not on Robin's named stack; off-scope per scope), **`49415893` "FDA clears blood test to aid evaluation for Alzheimer's disease"** (154 pts top, 73 cmts, washu.edu — Alzheimer's / blood-test diagnostic; **adjacent-not-promoted** per scope because Alzheimer's is not in Robin's 4 application domains — 3D cell culture, 3D bioprinting, neuroscience in vitro, organoid workflows — though the clinical-research framing has a tangentially neuroscience-adjacent axis), and **`49421554` "Coding expertise is going to collapse from AI reliance"** (202 pts top, 234 cmts, larsfaye.com — AI-coding talent-debate essay; **adjacent-not-promoted** per scope because coding-talent is not on Robin's named stack), see 2026-08-24 18:00 UTC entry below) · `~/.openwiki/connectors/hackernews/raw/2026-08-23T18-00-02-256Z/hackernews-results.json` (prior — **thirteenth pull since 2026-08-07 with an empty / noise-only Algolia lane on vendor queries**; **fully-zero Algolia lane on all 6 queries**: `organoid` / `CelVivo` / `3Brain` / `Cellink` / `openwiki` / `deepagents` each returned `nbHits=null / hits=0` — same shape as the 2026-08-21 fully-zero pull (the prior fully-zero pull was 2026-08-21); the 2026-08-22 pull had a noise-only lane (3 of 6 with substring noise, 3 clean zero) and the 2026-08-23 pull returns to fully-zero across all 6 — **two fully-zero Algolia lanes in three consecutive pulls**, confirming the empty-pulls-on-vendor-queries cadence is normal under the 6-query LLM-agent topic set, not an outage, no config-side intervention needed; the strongest named-stack-adjacent item is **`49409092` "What Is a Harness?"** (121 pts, 83 cmts, top, by `tosh` 2026-08-23, https://earendil.com/posts/what-is-a-harness/ — a definitional essay on agent harnesses; **strongest named-stack-adjacent item of the pull by direct agent-harness cross-walk** because (a) the **121-pt + 83-cmt top-feed engagement** is the third-highest top-feed engagement on the pull (after the off-scope `49402232` Why your local LLM feels dumber 450 pts + `49402189` Scrap Moxie 399 pts), (b) the **definitional framing "What Is a Harness?"** directly speaks to the agent-as-primary-compute-substrate narrative that `hermes-agent-v0-19-quicksilver` documents, and (c) it is the **6th entry in the now 11-day self-hosted-agentic-substrate cluster** — DeepSeek Harness `49285244` 422 pts 2026-08-13 → machine0 `49348136` 19 pts 2026-08-18 → OneCLI `49363710` 21 pts 2026-08-19 → self-hosted agentic software factory `49390463` 16 pts 2026-08-21 → Munder Difflin `49398152` 192 pts 2026-08-22 → **"What Is a Harness?" `49409092` 121 pts 2026-08-23** — six independent submissions across 11 days, total cluster engagement 791 pts), with the next named-stack-adjacent item being **`49402232` "Why your local LLM feels dumber than it is"** (450 pts top+best, 182 cmts, by `felineflock` 2026-08-23, https://forum.level1techs.com/t/why-your-local-llm-feels-dumber-than-it-is/253917 — **highest-engagement item of the pull** at 450 pts + 182 cmts; a Level1Techs forum post on local-LLM optimization; **adjacent-not-promoted** per scope because local-LLM optimization is not on Robin's named daily-driver stack — Hermes / MiniMax-M3+H3 / OpenWiki / RAGFlow / NocoDB / SeaFile / Codex CLI are the named agents and unsloth/MiniMax-M3-GGUF is the local-LLM run path — but the **direct local-LLM-stack cross-walk to the `MiniMax-m3` row** makes this the strongest local-LLM-adjacent item of the pull), and the third named-stack-adjacent item being **`49410097` "GLM-5.3 (open-weight) beat Anthropic/OpenAI models – for 1/5 the cost"** (141 pts top, 143 pts best, by `ed-is-ai` 2026-08-23, https://reinLine truncated
+- **Latest fetch:** `2026-08-25T18:00:30Z` (LLM-agent topic set: `organoid`, `CelVivo`, `3Brain`, `Cellink`, `openwiki`, `deepagents` — 6 queries; the source-specific instruction "Track organoid / CelVivo / 3Brain / Cellink / openwiki / AI agent stories" is the active query set; prior 2026-08-24 18:00, 2026-08-23 18:00, 2026-08-22 18:00, 2026-08-21 18:00, 2026-08-20 18:00, 2026-08-19 18:00, 2026-08-18 18:00, 2026-08-17 18:00, 2026-08-16 18:00, 2026-08-15 18:00, 2026-08-13 18:00, 2026-08-12 18:00, 2026-08-10 18:00, 2026-08-08 18:00, 2026-08-08 03:15, 2026-08-07 12:29, 2026-08-03 18:00, 2026-08-02 18:00, 2026-08-01 18:00, 2026-07-31 18:00, 2026-07-30 18:00, 2026-07-29 18:00, 2026-07-28 18:00, 2026-07-27 18:00, 2026-07-26 18:16 and 18:00 pulls also documented below)
+- **Raw dumps:** `~/.openwiki/connectors/hackernews/raw/2026-08-25T18-00-02-968Z/hackernews-results.json` (current — **fifteenth pull since 2026-08-07 with an empty / noise-only Algolia lane on vendor queries**; **fully-zero Algolia lane on all 6 queries**: `organoid` / `CelVivo` / `3Brain` / `Cellink` / `openwiki` / `deepagents` each returned `nbHits=null / hits=0` — same shape as the 2026-08-21 + 2026-08-23 fully-zero pulls, confirming the same fully-zero lane; the 2026-08-23 + 2026-08-24 + 2026-08-25 fully-zero pulls are three consecutive fully-zero pulls bookending the 2026-08-22 noise-only pull — **three fully-zero Algolia lanes in three consecutive pulls**, the **longest fully-zero Algolia streak in the 2026-08-07 streak to date** (four fully-zero bookends: 2026-08-21 + 2026-08-23 + 2026-08-24 + 2026-08-25), confirming the empty-pulls-on-vendor-queries cadence is normal under the 6-query LLM-agent topic set, not an outage, no config-side intervention needed; 30 unique top+best items, no in-scope vendor / customer / application-domain / named-stack signal — strongest adjacent item is **`49432317` "Qwen 3.8-Flash-Next releasing tomorrow (125B a6B)"** (244 pts modelscope.cn — **strongest open-weight-LLM-adjacent item of the pull by inference-lane impact**; open-weight Qwen family release, cross-walks to the `MiniMax-m3` row's open-weight comparison anchor; **adjacent-not-promoted** per scope because Qwen is not on Robin's named stack), see 2026-08-25 18:00 UTC entry below) · `~/.openwiki/connectors/hackernews/raw/2026-08-24T18-00-02-633Z/hackernews-results.json` (prior — **fourteenth pull since 2026-08-07 with an empty / noise-only Algolia lane on vendor queries**; **fully-zero Algolia lane on all 6 queries**: `organoid` / `CelVivo` / `3Brain` / `Cellink` / `openwiki` / `deepagents` each returned `nbHits=0 / hits=0` — the runtime payload reports clean integer `nbHits=0` (vs the `nbHits=null` shape on the 2026-08-21 + 2026-08-23 fully-zero pulls, both confirming the same fully-zero lane); the 2026-08-21 / 2026-08-23 / 2026-08-24 fully-zero pulls are bookends on the 2026-08-22 noise-only pull, **three fully-zero Algolia lanes in four consecutive pulls**, confirming the empty-pulls-on-vendor-queries cadence is normal under the 6-query LLM-agent topic set, not an outage, no config-side intervention needed; 38 unique top+best items, no in-scope vendor / customer / application-domain / named-stack signal — strongest weakly-adjacent items are **`49411102` "Anthropic's best AI model struggles to attract users as cheaper tools thrive"** (738 pts top+best, 649 cmts — **highest-engagement item of the pull**; FT business-model pressure on Anthropic's best AI model; **adjacent-not-promoted** per scope because Anthropic pricing pressure is not on Robin's named stack; off-scope per scope), **`49415893` "FDA clears blood test to aid evaluation for Alzheimer's disease"** (154 pts top, 73 cmts, washu.edu — Alzheimer's / blood-test diagnostic; **adjacent-not-promoted** per scope because Alzheimer's is not in Robin's 4 application domains — 3D cell culture, 3D bioprinting, neuroscience in vitro, organoid workflows — though the clinical-research framing has a tangentially neuroscience-adjacent axis), and **`49421554` "Coding expertise is going to collapse from AI reliance"** (202 pts top, 234 cmts, larsfaye.com — AI-coding talent-debate essay; **adjacent-not-promoted** per scope because coding-talent is not on Robin's named stack), see 2026-08-24 18:00 UTC entry below) · `~/.openwiki/connectors/hackernews/raw/2026-08-23T18-00-02-256Z/hackernews-results.json` (prior — **thirteenth pull since 2026-08-07 with an empty / noise-only Algolia lane on vendor queries**; **fully-zero Algolia lane on all 6 queries**: `organoid` / `CelVivo` / `3Brain` / `Cellink` / `openwiki` / `deepagents` each returned `nbHits=null / hits=0` — same shape as the 2026-08-21 fully-zero pull (the prior fully-zero pull was 2026-08-21); the 2026-08-22 pull had a noise-only lane (3 of 6 with substring noise, 3 clean zero) and the 2026-08-23 pull returns to fully-zero across all 6 — **two fully-zero Algolia lanes in three consecutive pulls**, confirming the empty-pulls-on-vendor-queries cadence is normal under the 6-query LLM-agent topic set, not an outage, no config-side intervention needed; the strongest named-stack-adjacent item is **`49409092` "What Is a Harness?"** (121 pts, 83 cmts, top, by `tosh` 2026-08-23, https://earendil.com/posts/what-is-a-harness/ — a definitional essay on agent harnesses; **strongest named-stack-adjacent item of the pull by direct agent-harness cross-walk** because (a) the **121-pt + 83-cmt top-feed engagement** is the third-highest top-feed engagement on the pull (after the off-scope `49402232` Why your local LLM feels dumber 450 pts + `49402189` Scrap Moxie 399 pts), (b) the **definitional framing "What Is a Harness?"** directly speaks to the agent-as-primary-compute-substrate narrative thaLine truncated
 
-## Latest update — 2026-08-24 18:00 UTC
+## Latest update — 2026-08-25 18:00 UTC
+
+- **Coverage:** 2 feeds (`top`, `best`), 6 search queries (the same simplified LLM-agent topic set from the source-specific instruction "Track organoid / CelVivo / 3Brain / Cellink / openwiki / AI agent stories": `organoid`, `CelVivo`, `3Brain`, `Cellink`, `openwiki`, `deepagents`). `top` feed had 30 IDs (28 resolved items), `best` feed had 30 IDs (8 resolved items); deduplication gave **30 unique items across both feeds** (6 overlap between top and best feeds). The 6-query lane returned **fully-zero hits across all six Algolia queries** — `organoid` / `CelVivo` / `3Brain` / `Cellink` / `openwiki` / `deepagents` each returned `nbHits=null / hits=0` in the 24 h window (the runtime payload on the 2026-08-25 pull reports `nbHits=null` rather than the clean integer `nbHits=0` shape on the 2026-08-24 pull, but the `hits=0` array length confirms the same fully-zero lane; this is the **second consecutive shape-variant of fully-zero Algolia lane** across the 2026-08-23 + 2026-08-24 + 2026-08-25 pulls); the connector completed normally at `fetchedAt: 2026-08-25T18:00:30.716Z` (24-hour window).
+- **Life-science lane:** **zero vendor-anchored hits across all four named vendor queries — and zero substring-noise hits as well.** All four Algolia vendor queries (`organoid`, `CelVivo`, `3Brain`, `Cellink`) returned `hits=0` in the 24 h window, with no string-collision noise on `organi-` / `brain` / `calling` / `ceiling` / `helsinki` substrings (the 2026-08-22 pull surfaced 1 thematic + 4 noise on `organoid`, 1 thematic + 5 noise on `3Brain`, and 3 noise on `Cellink`; the 2026-08-23 + 2026-08-24 + 2026-08-25 pulls return to fully-zero across all four vendor queries — **three consecutive fully-zero Algolia lanes on all four vendor queries**, the longest fully-zero streak of the 2026-08-07 streak). A title/URL regex sweep across the 30 unique top+best items also turned up **zero organoid / 3D-bioprinting / CelVivo / 3Brain / Cellink / ClinoStar / ClinoReactor / MEA / spheroid / organ-on-chip items** and **zero self-hosted-agentic-substrate cluster items** (the 6-item / 12-day cluster from DeepSeek Harness 2026-08-13 → machine0 2026-08-18 → OneCLI 2026-08-19 → self-hosted factory 2026-08-21 → Munder Difflin 2026-08-22 → "What Is a Harness?" 2026-08-23 has its **second consecutive quiet pull** on 2026-08-24 + 2026-08-25 — 6 items in 14 days with two misses, dropping cluster density from 0.55 entries/day to 0.43 entries/day). The "no material HN footprint for the 4 vendor lines" finding continues to hold — this is the **fifteenth pull since 2026-08-07 with an empty / noise-only Algolia lane on vendor queries** (after the 2026-08-08 03:15 + 2026-08-08 18:00 + 2026-08-13 + 2026-08-15 + 2026-08-16 + 2026-08-18 + 2026-08-19 + 2026-08-21 + 2026-08-23 + 2026-08-24 + 2026-08-25 fully-zero pulls + the 2026-08-10 + 2026-08-12 + 2026-08-17 + 2026-08-20 + 2026-08-22 noise-only pulls; the 2026-08-23 + 2026-08-24 + 2026-08-25 fully-zero pulls are three consecutive fully-zero pulls bookending the 2026-08-22 noise-only pull — **three fully-zero Algolia lanes in three consecutive pulls**, the **longest fully-zero Algolia streak in the 2026-08-07 streak to date** — confirming that the empty-pulls-on-vendor-queries cadence is normal under the 6-query LLM-agent topic set, not an outage, no config-side intervention needed). The Tavily (web-search) lane remains the productive lane for vendor news; the HN lane's stable role is now "high-engagement inference-lane / agent-stack adjacents + low-engagement application-domain watchlist items + low-engagement self-hosted-agentic-substrate cluster essays" rather than vendor-direct signals. The 30 unique top+best items include **zero matches** for any in-scope vendor / customer / application-domain / named-stack keyword — no CelVivo / 3Brain / Cellink / ClinoStar / ClinoReactor / MEA / spheroid / organ-on-chip / organoid / bioprinting hits; no Hermes / OpenClaw / MiniMax / RAGFlow / NocoDB / SeaFile / Codex-CLI direct release hits. The single open-weight-LLM-adjacent item on the pull is **`49432317` "Qwen 3.8-Flash-Next releasing tomorrow (125B a6B)"** (244 pts modelscope.cn — open-weight Qwen family release announcement; **adjacent-not-promoted** per scope because Qwen is not on Robin's named stack — the `MiniMax-m3` row already cites the 2026-08-01 benchlm.ai DeepSeek V4 Flash vs MiniMax M3 comparison anchor and the open-weight competitive set (DeepSeek V4 Flash / GLM / Qwen / Llama), and the Qwen 3.8-Flash-Next item reinforces the open-weight-LLM cluster without crossing the promotion threshold). The single AI-vendor-business-adjacent item is **`49434291` "Anthropic tells staff to work from home due to possible security team strike"** (89 pts Business Insider — Anthropic operational-distress signal; **adjacent-not-promoted** per scope because Anthropic operational issues are upstream competitive context, not a vendor-stack change Robin acts on; the existing `MiniMax-m3` row already cites the 2026-08-24 FT Anthropic pricing-pressure essay as the upstream AI-vendor-business anchor). Per the brief's "low-engagement items stay watchlist by default" rule + the `/themes.md` scope discipline, **none of the 30 unique items qualifies for a `/themes.md` row promotion on this pull**.
+- **Workflow lane:** **zero positive `openwiki` brand hits; zero `deepagents` hits.** `openwiki` and `deepagents` both returned `nbHits=null / hits=0` — so the `openwiki-brand` watchlist row on `/themes.md` stays at Last seen 2026-07-16. The 30 unique top+best items include **no directly-relevant item for any `/themes.md` row by vendor** and **no self-hosted-agentic-substrate cluster entry on this pull** (second consecutive quiet pull for the cluster after the 2026-08-23 "What Is a Harness?" entry), but include **three weakly-adjacent items worth flagging for traceability**: **`49432317` "Qwen 3.8-Flash-Next releasing tomorrow (125B a6B)"** (244 pts modelscope.cn — **strongest open-weight-LLM-adjacent item of the pull by inference-lane impact**; open-weight Qwen family release) + **`49434291` "Anthropic tells staff to work from home due to possible security team strike"** (89 pts Business Insider — Anthropic operational-distress signal, second AI-vendor-business-adjacent item after the 2026-08-24 FT Anthropic pricing essay) + **`49437152` "Water Behind the Watts: The Hidden Risk of Powering Data Centers"** (15 pts ceres.org — data-center water-usage adjacent to the AI-inference + data-center-energy narrative). Per the brief: low-engagement items stay watchlist by default; only high-engagement + directly-relevant items earn promotion. None of the 30 unique items crosses the promotion threshold:
+  - **`49432317` "Qwen 3.8-Flash-Next releasing tomorrow (125B a6B)"** (244 pts, **top feed**, by `garo-pro` 2026-08-25, https://modelscope.cn/models/Qwen/Qwen3.8-Flash-Next — ModelScope). A ModelScope model-card announcement for **Qwen 3.8-Flash-Next** (125B-parameter MoE with 6B active parameters, "releasing tomorrow" announcement format) — the open-weight Qwen family from Alibaba's Qwen team. **Strongest open-weight-LLM-adjacent item of the pull by inference-lane impact** because (a) **244-pt top-feed engagement** is the seventh-highest top-feed engagement on the pull (ahead of the off-scope items `49430007` Windows 95 85 pts + `49432227` HelloAssembly 70 pts + the Apple M5/M6 cluster — the Apple M5/M6 cluster dominates the top of the pull); (b) the **Qwen 3.8-Flash-Next "125B a6B" framing** cross-walks to the `MiniMax-m3` row's open-weight comparison anchor (DeepSeek V4 Flash / GLM / Qwen / Llama family) — Qwen 3.8-Flash-Next is the seventh open-weight-LLM-adjacent item in the 2026-08-07 streak after DeepSeek V4 Flash vision (379 pts 2026-08-21) + Unsloth Dynamic 3.0 GGUFs (314 pts 2026-08-19) + GLM-5.3 vs Anthropic/OpenAI (141 pts 2026-08-23) + Qwen 3.8 27B reverse-engineering (234 pts 2026-08-23) + GLM-5.3 tablet (268 pts 2026-08-23) + Qwen 3.8 27B tablet (sub-100 pts earlier); (c) the **ModelScope source** is the canonical Chinese open-weight model registry (Alibaba's hosted model hub); (d) the **125B / 6B-active MoE architecture** mirrors the open-weight-LLM scaling pattern that `MiniMax-m3` row's V4-Flash-comparison framework references. **Adjacent-not-promoted** per scope because (a) **Qwen 3.8-Flash-Next is not on Robin's named daily-driver stack** (Hermes / MiniMax-M3+H3 / OpenWiki / RAGFlow / NocoDB / SeaFile / Codex CLI are the named agents); (b) the established scope rule on non-named-stack open-weight LLM releases keeps them adjacent-not-promoted unless there is a direct change to Hermes / MiniMax / OpenWiki / Codex CLI itself (per the 2026-07-30 / 2026-08-03 / 2026-08-10 / 2026-08-12 / 2026-08-13 / 2026-08-15 / 2026-08-16 / 2026-08-17 / 2026-08-18 / 2026-08-19 / 2026-08-20 / 2026-08-21 / 2026-08-22 / 2026-08-23 / 2026-08-24 traceability entries); (c) the brief's "Workflow tooling priority LOW — surface story-worthy changes only" rule does not promote a 244-pt Qwen 3.8-Flash-Next model-card announcement to a `/themes.md` row by itself, though the **direct open-weight-LLM cross-walk to the `MiniMax-m3` row's open-weight comparison anchor + the seventh open-weight-LLM-adjacent item in the streak** make this the strongest open-weight-LLM-adjacent item of the pull. Flagged for traceability because (a) the **244-pt engagement is the highest top-feed engagement on a non-Apple item of the pull** — the Apple M5/M6 / M6/M5 Ultra cluster dominates the top engagement (629 + 582 + 523 + 288 pts across four items), but the Qwen item is the highest non-Apple engagement on the pull; (b) the **Qwen 3.8-Flash-Next model-card announcement** is the first Qwen-flash-family item since the 2026-08-23 Qwen 3.8 27B reverse-engineering item (`49407507` 234 pts); (c) the **open-weight-LLM cluster now totals 1,010+ pts across 7 items in the 2026-08-07 streak** (379 + 314 + 141 + 234 + 268 + 244 = 1,580+ pts including the off-scope GLM-5.3-tablet entry); (d) any future HN item at higher engagement combining Qwen 3.8-Flash-Next + explicit MiniMax-M3 / Hermes Agent / unsloth-MiniMax-M3-GGUF integration notes becomes the first corroborating event for a `MiniMax-m3-row-annex-open-weight-multimodal-parity` annex on the existing row. **No commitment row** — Qwen 3.8-Flash-Next is a vendor capability release announcement, not a vendor-stack change Robin acts on; the existing `MiniMax-m3` row is the canonical synthesis home. **No open-question row, no `/themes.md` row change** — `MiniMax-m3` stays at Last seen 2026-08-03 (no MiniMax model release; the Qwen announcement is upstream open-weight-LLM context, not a MiniMax-side change).
+  - **`49434291` "Anthropic tells staff to work from home due to possible security team strike"** (89 pts, **top feed**, by `DGAP` 2026-08-25, https://www.businessinsider.com/anthropic-san-francisco-staff-work-remote-office-security-strike-2026-8 — Business Insider). A Business Insider report on **Anthropic asking San Francisco staff to work from home due to a possible security team strike** — Anthropic operational-distress signal. **Strongest AI-vendor-business-adjacent item of the pull by Anthropic operational context** because (a) **89-pt top-feed engagement** is moderate — below the 100-pt vendor-release refresh bar but the highest Anthropic operational-distress item in the 2026-08-07 streak; (b) the **Business Insider source** is a credible business-news outlet; (c) the **Anthropic operational-distress framing** (security team strike + WFH mandate) cross-walks to the broader Anthropic-competitive-pressure narrative that the 2026-08-24 FT "Anthropic's best AI model struggles to attract users as cheaper tools thrive" essay (738 pts) + the 2026-08-19 Unsloth Dynamic 3.0 GGUFs + the 2026-07-29 MyClaw.ai MiniMax-M3 multimodal confirmation + the 2026-08-01 benchlm.ai DeepSeek V4 Flash vs MiniMax M3 comparison already document — Anthropic is under simultaneous product (pricing pressure) + operational (security team strike) pressure; (d) the **Anthropic-operational-distress framing** is the **first HN item since the 2026-08-13 `DeepSeek Harness` (422 pts)** to surface a specific Anthropic operational risk — the security team strike + WFH mandate is the first Anthropic-operational-distress item in the 2026-08-07 streak. **Adjacent-not-promoted** per scope because (a) **Anthropic operational distress is upstream-of-MiniMax competitive context, not a vendor-stack change Robin acts on**; (b) the established scope rule on non-named-stack AI-vendor business essays keeps them adjacent-not-promoted unless there is a direct change to Hermes / MiniMax / OpenWiki / Codex CLI itself (per the 2026-07-30 / 2026-08-03 / 2026-08-10 / 2026-08-12 / 2026-08-13 / 2026-08-15 / 2026-08-16 / 2026-08-17 / 2026-08-18 / 2026-08-19 / 2026-08-20 / 2026-08-21 / 2026-08-22 / 2026-08-23 / 2026-08-24 traceability entries); (c) the brief's "Workflow tooling priority LOW — surface story-worthy changes only" rule does not promote an 89-pt Anthropic-operational-distress item to a `/themes.md` row by itself, though the **direct AI-vendor-pricing + AI-vendor-operational cross-walk to the `MiniMax-m3` row's open-weight comparison anchor (DeepSeek V4 Flash / GLM / Qwen / Llama — open-weight competitive set pressuring closed-weight pricing + Anthropic operational strain)** make this a corroborating AI-vendor-business-stack signal alongside the 2026-08-24 FT Anthropic pricing-pressure essay. Flagged because (a) the **direct AI-vendor-pricing + AI-vendor-operational cross-walk to the `MiniMax-m3` row** makes this a corroborating AI-vendor-business-stack signal alongside the 2026-08-24 FT Anthropic pricing-pressure essay + the 2026-08-19 Unsloth Dynamic 3.0 GGUFs + the 2026-07-29 MyClaw.ai MiniMax-M3 multimodal confirmation + the 2026-08-01 benchlm.ai DeepSeek V4 Flash vs MiniMax M3 comparison + the 2026-08-21 DeepSeek-v4-flash-vision release; (b) the **Anthropic-operational-distress framing** is a new operational risk dimension not previously surfaced in the streak (the 2026-08-24 FT Anthropic essay covered pricing pressure, not operational distress); (c) any future HN item combining Anthropic / OpenAI operational distress + concrete open-weight vendor stability (e.g., Qwen / GLM / DeepSeek stability reports) becomes the first corroborating event for a `MiniMax-m3-row-annex-open-weight-vs-closed-weight-stability` annex on the existing row. **No commitment row** — Anthropic operational distress is upstream competitive context, not a vendor-stack change Robin acts on; the existing `MiniMax-m3` row is the canonical synthesis home. **No open-question row, no `/themes.md` row change** — `MiniMax-m3` stays at Last seen 2026-08-03 (no MiniMax model release; the Anthropic operational-distress item is upstream AI-vendor business context, not a MiniMax-side change).
+  - **`49437152` "Water Behind the Watts: The Hidden Risk of Powering Data Centers"** (15 pts, **top feed**, by `hn_acker` 2026-08-25, https://www.ceres.org/resources/reports/water-behind-the-watts-the-hidden-risk-of-powering-data-centers — Ceres). A Ceres report on **water-resource risk of data-center power consumption** — a sustainability/energy-resource analysis adjacent to the AI-inference + data-center-energy narrative. **Only data-center-energy-adjacent item on the pull** because (a) the **Ceres source** is a credible sustainability-research non-profit; (b) the **water-resource framing** is a new dimension not previously surfaced in the 2026-08-07 streak (the streak has covered data-center capacity + AI-vendor pricing + AI-vendor operational distress, but not the water-resource side); (c) the **data-center-energy / AI-inference correlation** is implicit in the report (AI inference / training workloads are a primary driver of data-center power + water consumption). **Adjacent-not-promoted** per scope because (a) **15-pt engagement is well below the established refresh thresholds** (100-pt vendor-release / 50-pt clinical-translation / 21-pt OneCLI / 19-pt machine0 / 46-pt MCP Memory refresh triggers); (b) **data-center water-resource sustainability is not on Robin's named daily-driver stack or 4 application domains** (3D cell culture, 3D bioprinting, neuroscience in vitro, organoid workflows); (c) the established scope rule on non-named-stack / non-application-domain sustainability reports keeps them adjacent-not-promoted unless there is a direct change to the named stack or 4 application domains (per the 2026-08-20 Hubble-radiation-damage astronomy paper's "off-scope per scope discipline" precedent). Flagged because (a) it is the **only data-center-energy / AI-inference-adjacent sustainability item on the 2026-08-07 streak** — the first water-resource framing in the streak; (b) any future HN item at higher engagement combining data-center water / energy sustainability + AI-inference / training-workload context becomes the first corroborating event for a `class-organoid-3d-bioprinting` description extension on environmental sustainability evidence; (c) the 15-pt engagement is too low for theme-row Last-seen refresh but the **novel "water-resource AI-infrastructure sustainability" framing** is worth noting for traceability. **No commitment row, no open-question row, no `/themes.md` row change** — the data-center water-resource sustainability report is upstream environmental context, not a vendor-stack change Robin acts on.
+  - **Two secondary adjacents worth noting for traceability:** **`49436400` "Run Minecraft in a Windows Sandbox for Computer Use Agents"** (6 pts, **top feed**, by `someguy101010` 2026-08-25, https://cua.ai/docs/how-to-guides/sandbox/minecraft — cua.ai docs). A cua.ai how-to for **running Minecraft in a Windows Sandbox for Computer Use Agents** — a computer-use-agent stack-adjacent item. **Adjacent-not-promoted** per scope because (a) **6-pt engagement is well below the refresh thresholds**; (b) cua.ai is **not on Robin's named stack** (Hermes / MiniMax-M3+H3 / OpenWiki / RAGFlow / NocoDB / SeaFile / Codex CLI are the named agents); (c) the computer-use-agent lane is tangential to Robin's workflow (Robin uses Codex CLI for coding-agent work, not computer-use-agent work); (d) the brief's scope rule keeps non-named-stack agent-infrastructure how-tos adjacent-not-promoted. **No commitment row, no `/themes.md` row change**. **`49435781` "Warnock: Harnessing GPU Geometry Amplification for Vector Graphics"** (17 pts, **top feed**, by `coffeeaddict1` 2026-08-25, https://dl.acm.org/doi/pdf/10.1145/3820012 — ACM Digital Library). An ACM SIGGRAPH paper on **GPU geometry amplification for vector graphics rendering** — uses "Harnessing" in the title but is GPU geometry amplification for vector graphics rendering, not agent harness — **name collision only**. **Adjacent-not-promoted** per scope because (a) **17-pt engagement is well below the refresh thresholds**; (b) GPU geometry amplification for vector graphics is **not on Robin's named stack** and not in the 4 application domains; (c) the "harness" word-collision is unrelated to the `hermes-agent-v0-19-quicksilver` row's harness-architecture anchor — the item is about a different "harness" (GPU rendering pattern). **No commitment row, no `/themes.md` row change**.
+  - **No self-hosted-agentic-substrate cluster entry on this pull:** the 6-item / 12-day cluster from DeepSeek Harness `49285244` 422 pts 2026-08-13 → machine0 `49348136` 19 pts 2026-08-18 → OneCLI `49363710` 21 pts 2026-08-19 → self-hosted agentic software factory `49390463` 16 pts 2026-08-21 → Munder Difflin `49398152` 192 pts 2026-08-22 → "What Is a Harness?" `49409092` 121 pts 2026-08-23 has its **second consecutive quiet pull** on 2026-08-24 + 2026-08-25 — 6 cluster items in 14 days with two misses is **a cooling cluster density pattern** (6-hit density averaged 0.55 entries/day over 11 days through 2026-08-23, dropping to 0.43 entries/day over 14 days with two quiet pulls on 2026-08-24 + 2026-08-25). The 30 unique top+best items include zero items matching `harness` (in the agent-harness sense — `49435781` Warnock GPU geometry amplification uses "Harnessing" but is a graphics-rendering paper, not an agent-harness item) / `agent` / `MCP` / `model context protocol` / `OpenClaw` / `Hermes` / `NanoClaw` / `Munder Difflin` / `Machine0` / `OneCLI` / `self-hosted` / `agentic software` — the cluster has had no new cluster entry on this pull but the **prior cluster density of 6 entries in 11 days through 2026-08-23 + the recent refresh on 2026-08-23 with "What Is a Harness?" at 121 pts + the cluster's continued cross-walk to Hermes Agent's harness architecture** keep the cluster relevant; any cluster entry on a future pull becomes the next `hermes-agent-v0-19-quicksilver` Last-seen refresh candidate. The cooling density is worth flagging because the cluster is now a recurring-signal watchlist candidate that has not produced a new entry in two consecutive pulls — the next cluster entry will determine whether the cluster remains an active emerging-pattern or settles into a single-pulse historical pattern.
+  - **Highest-engagement items off-scope:** the remaining 25 of 30 unique top+best items fall outside Robin's named stack + 4 application domains per the brief's scope filter — **`49424606` "Oceans hit highest temperature on record"** (667 pts top — BBC climate, off-scope); **`49433292` "Apple introduces M6 and M5 Ultra"** (629 pts top — Apple newsroom, off-scope); **`49426564` "iCloud+ Hide My Email addresses will remain on icloud.com"** (582 pts top — Apple developer, off-scope); **`49433316` "New Mac Studio with M5 Max and M5 Ultra"** (523 pts top — Apple newsroom, off-scope); **`49433450` "New Mac mini, featuring M6 and M5 Pro"** (288 pts top — Apple newsroom, off-scope); **`49426466` "Moon (2024)"** (250 pts top — ciechanow.ski interactive essay, off-scope); **`49432319` "Don't Wordle"** (229 pts top — personal-blog game, off-scope); **`49434820` "Bomb fishing is wreaking havoc on Indonesia's coral reefs"** (159 pts top — environmental, off-scope); **`49434645` "Building a backyard office, the build and cost breakdown"** (133 pts top — personal blog, off-scope); **`49437283` "Nitter project received cease and desist"** (117 pts top — open-source legal, off-scope); **`49430007` "Windows 95 released August 24, 1995"** (85 pts top — anniversary, off-scope); **`49432227` "HelloAssembly The smallest possible complete Windows application"** (70 pts top — assembly tutorial, off-scope); **`49436822` "SpaceX – Starbase, LA"** (45 pts top — space, off-scope); **`49437069` "My Friend Aaron"** (41 pts top — personal essay, off-scope); **`49437210` "Black hole singularity is a surface not a point"** (29 pts top — arxiv, off-scope); **`49435495` "Beyond Good and Evil: Nietzsche and the Great War (2019)"** (24 pts top — history, off-scope); **`49434613` "MySQL CDC to BigQuery: what periodic syncs miss, and how binlog avoids it"** (24 pts top — engineering blog, off-scope); **`49436786` "Tooltips Need a Delay, and Then They Need to Skip It"** (20 pts top — UI engineering, off-scope); **`49423878` "Visualizing Binary Files"** (20 pts top — visualization essay, off-scope); **`49437165` "A new ceiling for Λ: the de Bruijn–Newman constant is at most 0.1787854"** (15 pts top — math, off-scope); **`49437049` "LatticeDB – Like SQLite but for graph databases"** (14 pts top — Show HN, off-scope); **`49436706` "Fuzzing the Gleam Compiler"** (9 pts top — programming, off-scope); **`49437483` "Run OpenBSD on DigitalOcean for $4/month"** (7 pts top — hosting, off-scope); **`49437361` "Lightweight system monitor for Linux VPS written in Go"** (7 pts top — sysadmin, off-scope); **`49437566` "Clara (YC P26) Is Hiring a Growth Engineer to Bring AI Doctors to Market"** (1 pt top — YC job, off-scope). Engagement range 1–667 pts across the 30 items; **0 items match a Robin in-scope vendor / customer / application-domain / named-stack keyword** (no CelVivo / 3Brain / Cellink / ClinoStar / ClinoReactor / MEA / spheroid / organ-on-chip / organoid / bioprinting hits; no Hermes / OpenClaw / MiniMax / RAGFlow / NocoDB / SeaFile / Codex-CLI direct release hits), **0 items match Robin's broader agent-stack or substrate lane** (no `harness` / `MCP` / `OpenClaw` / `Hermes` / `Munder Difflin` / `machine0` / `OneCLI` / `self-hosted` / `agentic` entries — **second pull in the 2026-08-07 streak with zero self-hosted-agentic-substrate cluster items**), **0 items match Robin's broader local-LLM lane**, **3 items match Robin's broader AI-vendor / open-weight-LLM / data-center-energy lanes loosely** (`49432317` Qwen 3.8-Flash-Next open-weight-LLM, `49434291` Anthropic work-from-home AI-vendor-business, `49437152` data-center water-usage AI-infrastructure-adjacent), **2 items are secondary adjacents** (`49436400` cua.ai Minecraft computer-use-agent, `49435781` Warnock GPU geometry amplification — graphics-rendering paper with "Harnessing" word-collision only). Per the brief: low-engagement items stay watchlist by default; only high-engagement + directly-relevant items earn promotion. None of the 30 unique items crosses the promotion threshold — the highest-engagement item matching Robin's broader open-weight-LLM lane is `49432317` Qwen 3.8-Flash-Next at 244 pts, which is the strongest open-weight-LLM-adjacent item of the pull but stays adjacent-not-promoted per the established scope rule (Qwen is not on Robin's named stack); the highest-engagement item matching Robin's broader AI-vendor-business lane is `49434291` Anthropic work-from-home at 89 pts, which is the strongest AI-vendor-operational-distress-adjacent item of the pull but stays adjacent-not-promoted per scope (Anthropic operational issues are upstream competitive context, not a vendor-stack change Robin acts on); the only data-center-energy-adjacent item is `49437152` data-center water at 15 pts, which stays adjacent-not-promoted per scope (water-resource sustainability is not in Robin's 4 application domains).
+- **Synthesis result:** **no theme refresh, no commitment row, no open-question row, no personal-logistics item.** The `class-organoid-3d-bioprinting` row on `/themes.md` stays at Last seen 2026-08-20 (no organoid / 3D-bioprinting / CelVivo / 3Brain / Cellink item — the 30 unique feed items include zero application-domain matches; the closest items are `49434820` Bomb fishing coral reefs (environmental, off-scope per scope) + `49437152` data-center water (water-resource sustainability, off-scope per scope); the prior 2026-08-20 refresh from the `49366519` Nature organoid-time-passage paper + `49373812` Science Alert write-up carries forward unchanged). The `agent-memory-architecture` row stays at Last seen 2026-08-13 (no OKF / MCP Memory / Karpathy LLM Wiki / Agent Mesh item; the 30 unique items include zero agent-memory items; the MCP Memory OKF+memory schema event is the canonical row anchor, and the 2026-08-25 pull adds zero evidence to that anchor). The `MiniMax-m3` row stays at Last seen 2026-08-03 (no MiniMax model release; `49432317` Qwen 3.8-Flash-Next is **the strongest open-weight-LLM-adjacent item of the pull by inference-lane impact** at 244 pts but stays adjacent-not-promoted per scope because Qwen is not on Robin's named stack — the existing `MiniMax-m3` row already cites the benchlm.ai 2026-08-01 V4-Flash-vs-M3 framing + the unsloth `unsloth/MiniMax-M3-GGUF` quantized local-LLM run path + the MyClaw.ai 2026-07-29 multimodal confirmation + the Hermes Agent MiniMax-M3 default-model designation, so the Qwen 3.8-Flash-Next announcement is an incremental upstream open-weight-LLM signal rather than a MiniMax-side change; `49434291` Anthropic work-from-home is **the strongest AI-vendor-business-adjacent item of the pull** at 89 pts but stays adjacent-not-promoted per scope because Anthropic operational distress is upstream competitive context, not a vendor-stack change Robin acts on; the existing `MiniMax-m3` row already cites the 2026-08-24 FT Anthropic pricing-pressure essay as the upstream AI-vendor-business anchor, so the Anthropic work-from-home item is an incremental upstream operational-distress signal rather than a MiniMax-side change). The `hermes-agent-v0-19-quicksilver` row stays at Last seen 2026-08-03 (no Hermes Agent release; **zero self-hosted-agentic-substrate cluster entries on this pull** — the second consecutive quiet pull in the cluster since 2026-08-13 — but the cluster density of 6 entries in 12 days through 2026-08-23 + the recent refresh on 2026-08-23 with "What Is a Harness?" at 121 pts carries forward unchanged; the cluster is now in cooling-density territory with two consecutive quiet pulls; any future cluster entry + Hermes Agent / OpenWiki / Codex CLI release notes on the same pull becomes the first named-stack adoption event for the agent-harness substrate). The `openwiki-brand` watchlist row stays at Last seen 2026-07-16 (no positive `openwiki` hits — clean zero across both feed sweep and Algolia lane). The `china-cde-cell-gene-therapy-rules-2026` and `china-order-no-818-clinical-translation` watchlist rows stay at Last seen 2026-07-24 / 2026-07-28 (no China regulatory items on this pull). All three flag-for-traceability items stay adjacent-not-promoted under the existing scope discipline, and the two secondary adjacents (`49436400` cua.ai Minecraft + `49435781` Warnock GPU geometry amplification) also stay adjacent-not-promoted. **Key calls**:
+  - **`49432317` Qwen 3.8-Flash-Next "releasing tomorrow (125B a6B)"** is the **strongest open-weight-LLM-adjacent item of the pull by inference-lane impact** by virtue of (a) the **244-pt top-feed engagement** — the seventh-highest top-feed engagement on the pull (the Apple M5/M6 cluster dominates the top of the pull: 629 + 582 + 523 + 288 pts across four items + `49424606` Oceans 667 pts + `49426466` Moon 250 pts + `49432319` Don't Wordle 229 pts); (b) the **Qwen 3.8-Flash-Next "125B a6B" framing** is a Qwen-flash-family MoE architecture that mirrors the open-weight-LLM scaling pattern that `MiniMax-m3` row's V4-Flash-comparison framework references; (c) the **ModelScope source** is the canonical Chinese open-weight model registry (Alibaba's hosted model hub), reinforcing the open-weight-LLM cluster density; (d) **seventh open-weight-LLM-adjacent item in the 2026-08-07 streak** after DeepSeek V4 Flash vision (379 pts 2026-08-21) + Unsloth Dynamic 3.0 GGUFs (314 pts 2026-08-19) + GLM-5.3 vs Anthropic/OpenAI (141 pts 2026-08-23) + Qwen 3.8 27B reverse-engineering (234 pts 2026-08-23) + GLM-5.3 tablet (268 pts 2026-08-23) + Qwen 3.8-Flash-Next (244 pts 2026-08-25) — **1,580+ pts across 6 top-feed items in 6 pulls over 8 days** (the open-weight-LLM cluster density is the **strongest sustained engagement cluster in the 2026-08-07 streak**). **Adjacent-not-promoted** per scope (Qwen 3.8-Flash-Next is a vendor capability release announcement, not a named-stack change for Robin; the established scope rule keeps non-named-stack open-weight LLM releases adjacent-not-promoted unless there is a direct change to Hermes / MiniMax / OpenWiki / Codex CLI itself). Flagged because (a) the **direct open-weight-LLM cross-walk to the `MiniMax-m3` row's V4-Flash-comparison anchor** makes this a corroborating open-weight-LLM-stack signal alongside the 2026-08-19 Unsloth Dynamic 3.0 GGUFs + the 2026-07-29 MyClaw.ai MiniMax-M3 multimodal confirmation + the 2026-08-01 benchlm.ai DeepSeek V4 Flash vs MiniMax M3 comparison + the 2026-08-21 DeepSeek-v4-flash-vision release + the 2026-08-23 GLM-5.3 cluster + the 2026-08-23 Qwen 3.8 27B reverse-engineering item; (b) the **ModelScope source** is the canonical Chinese open-weight model registry — directly relevant to the China-side open-weight ecosystem that Robin's 济南成全 / 成都百乐 / 成都立德赛 distributor analysis touches; (c) the **Qwen 3.8-Flash-Next 125B / 6B-active MoE architecture** mirrors the V4-Flash architecture pattern that the benchlm.ai 2026-08-01 comparison framework references; (d) any future HN item at higher engagement combining Qwen 3.8-Flash-Next + explicit MiniMax-M3 multimodal parity benchmarks becomes the first corroborating event for a `MiniMax-m3-row-annex-open-weight-multimodal-parity` annex on the existing row. **No commitment row, no `/themes.md` row change** — the Qwen announcement is upstream open-weight-LLM context; if Robin applies the open-weight comparison analysis to a specific MiniMax-M3-GGUF deployment on a future pull, that becomes a downstream commitment.
+  - **`49434291` Anthropic "tells staff to work from home due to possible security team strike"** is the **strongest AI-vendor-business-adjacent item of the pull by Anthropic operational-distress context** by virtue of (a) the **89-pt top-feed engagement** — moderate engagement, below the 100-pt vendor-release refresh bar but the highest Anthropic-operational-distress item in the 2026-08-07 streak; (b) the **Business Insider source** is a credible business-news outlet; (c) the **Anthropic operational-distress framing** (security team strike + WFH mandate) cross-walks to the broader Anthropic-competitive-pressure narrative that the 2026-08-24 FT Anthropic pricing-pressure essay (738 pts) already documented — Anthropic is under simultaneous product (pricing pressure) + operational (security team strike) pressure; (d) the **Anthropic-operational-distress framing** is the **first HN item since the 2026-08-13 `DeepSeek Harness` (422 pts)** to surface a specific Anthropic operational risk — the security team strike + WFH mandate is the first Anthropic-operational-distress item in the 2026-08-07 streak. **Adjacent-not-promoted** per scope (the Business Insider item is an AI-vendor business/operational essay, not a named-stack change for Robin; the established scope rule keeps non-named-stack AI-vendor business essays adjacent-not-promoted unless there is a direct change to Hermes / MiniMax / OpenWiki / Codex CLI itself). Flagged because (a) the **direct AI-vendor-pricing + AI-vendor-operational cross-walk to the `MiniMax-m3` row's open-weight comparison anchor** makes this a corroborating AI-vendor-business-stack signal alongside the 2026-08-24 FT Anthropic pricing-pressure essay + the 2026-08-19 Unsloth Dynamic 3.0 GGUFs + the 2026-07-29 MyClaw.ai MiniMax-M3 multimodal confirmation + the 2026-08-01 benchlm.ai DeepSeek V4 Flash vs MiniMax M3 comparison + the 2026-08-21 DeepSeek-v4-flash-vision release + the 2026-08-25 Qwen 3.8-Flash-Next announcement; (b) the **Anthropic-operational-distress framing** is a new operational risk dimension not previously surfaced in the streak (the 2026-08-24 FT Anthropic essay covered pricing pressure, not operational distress); (c) the **two-pull FT/BI cluster on AI-vendor governance + AI-vendor operational-distress** (2026-08-24 FT pricing essay + 2026-08-25 BI operational-distress item) reinforces the broader Anthropic-pressure narrative; (d) any future HN item combining Anthropic / OpenAI operational distress + concrete open-weight vendor stability (e.g., Qwen / GLM / DeepSeek stability reports) becomes the first corroborating event for a `MiniMax-m3-row-annex-open-weight-vs-closed-weight-stability` annex on the existing row. **No commitment row, no `/themes.md` row change** — the Anthropic operational-distress item is upstream AI-vendor business context; if Robin applies the open-weight-vs-closed-weight stability analysis to a specific MiniMax-M3-GGUF deployment on a future pull, that becomes a downstream commitment.
+  - **`49437152` Ceres "Water Behind the Watts: The Hidden Risk of Powering Data Centers"** is the **only data-center-energy / AI-infrastructure-sustainability-adjacent item on the 2026-08-25 top+best feed lane** by virtue of (a) the **Ceres source** — a credible sustainability-research non-profit; (b) the **water-resource framing** is a new dimension not previously surfaced in the 2026-08-07 streak (the streak has covered data-center capacity + AI-vendor pricing + AI-vendor operational distress, but not the water-resource side); (c) the **data-center-energy / AI-inference correlation** is implicit in the report (AI inference / training workloads are a primary driver of data-center power + water consumption). **Adjacent-not-promoted** per scope (water-resource sustainability is not on Robin's named stack or 4 application domains; 15-pt engagement is well below all refresh thresholds; off-scope per scope discipline). Flagged because (a) it is the **only data-center-energy / AI-infrastructure-sustainability item on the 2026-08-25 top+best feed lane** — the first water-resource framing in the 2026-08-07 streak; (b) any future HN item at higher engagement combining data-center water / energy sustainability + AI-inference / training-workload context becomes the first corroborating event for a `class-organoid-3d-bioprinting` description extension on environmental sustainability evidence; (c) the 15-pt engagement is too low for theme-row Last-seen refresh but the **novel "water-resource AI-infrastructure sustainability" framing** is worth noting for traceability. **No commitment row, no open-question row, no `/themes.md` row change** — the data-center water-resource sustainability report is upstream environmental context, not a vendor-stack change Robin acts on.
+  - **This is the fifteenth pull since 2026-08-07 with an empty / noise-only Algolia lane on vendor queries** (after the 2026-08-08 03:15 + 2026-08-08 18:00 + 2026-08-13 + 2026-08-15 + 2026-08-16 + 2026-08-18 + 2026-08-19 + 2026-08-21 + 2026-08-23 + 2026-08-24 + 2026-08-25 fully-zero pulls + the 2026-08-10 + 2026-08-12 + 2026-08-17 + 2026-08-20 + 2026-08-22 noise-only pulls; the 2026-08-25 pull is the **third consecutive fully-zero pull bookended with the noise-only 2026-08-22 pull** — three fully-zero Algolia lanes in three consecutive pulls — confirming that the empty-pulls-on-vendor-queries cadence is normal under the 6-query LLM-agent topic set, not an outage, no config-side intervention needed). The pattern confirms that the empty-pulls-on-vendor-queries cadence is normal under the 6-query LLM-agent topic set. The Tavily (web-search) lane remains the productive lane for vendor news; the HN lane's stable role is now "high-engagement inference-lane / agent-stack adjacents (Qwen 3.8-Flash-Next + Anthropic operational-distress + data-center water + What Is a Harness? + GLM-5.3 cluster + Qwen 3.8 27B + FT Anthropic essay + AI-coding-expertise-collapse + Munder Difflin + New MCP Roadmap + OzBrain + DeepSeek V4 Flash vision + Proliferate + machine0 + OneCLI + OpenRouter-Stripe confirmation + Copilot Autofix + Unsloth Dynamic 3.0 GGUFs + AGENTS.md + FDA Alzheimer's + cua.ai Minecraft + Warnock GPU geometry amplification) + low-engagement application-domain watchlist items (organoid / neuroscience / Wired features / clinical-research papers) + low-engagement self-hosted-agentic-substrate cluster essays (DeepSeek Harness + machine0 + OneCLI + self-hosted factory + Munder Difflin + What Is a Harness?)" rather than vendor-direct signals. The 6-overlap dedup count between `top` and `best` (30 unique from 28+8) is **higher overlap ratio than prior pulls** (the 2026-08-24 pull had 5-overlap from 28+15 = 38 unique, the 2026-08-23 pull had 12-overlap from 28+15 = 31 unique, the 2026-08-22 pull had 3-overlap from 16+5 = 18 unique, the 2026-08-21 pull had 5-overlap from 28+13 = 36 unique); the 6-overlap on 2026-08-25 is driven by `best` resolving only 8 items — same low resolution as the 2026-08-22 pull — and a slightly higher `top` resolution (28 vs 28 on 2026-08-24). The 30 unique items are a -8 drop from the 2026-08-24 pull (which had 38 unique) — consistent with the 24-hour window having a denser feed on 2026-08-24 than 2026-08-25 (a 21% decrease in unique items).
+
+| Query lane | Queries run | Qualifying results |
+| --- | --- | --- |
+| Life sciences / vendors (fully zero) | `organoid`, `CelVivo`, `3Brain`, `Cellink` | 0 (all four queries returned `nbHits=null / hits=0` — **fully-zero Algolia lane on all four vendor queries, no substring-noise hits this pull**) |
+| AI workflow (fully zero) | `openwiki`, `deepagents` | 0 (both queries returned `nbHits=null / hits=0`) |
+
+Raw dump: `~/.openwiki/connectors/hackernews/raw/2026-08-25T18-00-02-968Z/hackernews-results.json`.
+
+### Flag-for-traceability: Qwen 3.8-Flash-Next "releasing tomorrow" (244 pts, seventh open-weight-LLM-adjacent item in the streak, strongest open-weight-LLM-adjacent item of the pull), Anthropic tells staff to work from home due to possible security team strike (89 pts, strongest AI-vendor-business-adjacent item of the pull by Anthropic operational-distress context), Ceres Water Behind the Watts data-center water report (15 pts, only data-center-energy-adjacent item on the pull, first water-resource framing in the streak) + cua.ai Minecraft computer-use-agent how-to (6 pts, secondary adjacency) + Warnock GPU geometry amplification for vector graphics (17 pts, secondary adjacency with "Harnessing" name-collision only) — adjacent, off-scope
+
+- **49432317** (244 pts top) **"Qwen 3.8-Flash-Next releasing tomorrow (125B a6B)"** — ModelScope model-card announcement (`garo-pro` 2026-08-25, https://modelscope.cn/models/Qwen/Qwen3.8-Flash-Next — ModelScope, Alibaba's hosted model hub). A ModelScope model-card announcement for **Qwen 3.8-Flash-Next** — the open-weight Qwen family from Alibaba, "125B-parameter MoE with 6B-active" architecture, "releasing tomorrow" announcement format. **Strongest open-weight-LLM-adjacent item of the pull by inference-lane impact** because (a) **244-pt top-feed engagement** is the seventh-highest top-feed engagement on the pull (the Apple M5/M6 cluster dominates the top of the pull at 629 + 582 + 523 + 288 pts across four items + `49424606` Oceans 667 pts + `49426466` Moon 250 pts + `49432319` Don't Wordle 229 pts); (b) the **Qwen 3.8-Flash-Next "125B a6B" framing** cross-walks to the `MiniMax-m3` row's open-weight comparison anchor (DeepSeek V4 Flash / GLM / Qwen / Llama family); (c) **seventh open-weight-LLM-adjacent item in the 2026-08-07 streak** after DeepSeek V4 Flash vision (379 pts 2026-08-21) + Unsloth Dynamic 3.0 GGUFs (314 pts 2026-08-19) + GLM-5.3 vs Anthropic/OpenAI (141 pts 2026-08-23) + Qwen 3.8 27B reverse-engineering (234 pts 2026-08-23) + GLM-5.3 tablet (268 pts 2026-08-23) + Qwen 3.8-Flash-Next (244 pts 2026-08-25) — **1,580+ pts across 6 top-feed items in 6 pulls over 8 days** (the open-weight-LLM cluster is the strongest sustained engagement cluster in the 2026-08-07 streak); (d) the **ModelScope source** is the canonical Chinese open-weight model registry (Alibaba's hosted model hub); (e) the **125B / 6B-active MoE architecture** mirrors the V4-Flash architecture pattern that the benchlm.ai 2026-08-01 comparison framework references. **Adjacent-not-promoted** per scope because (a) **Qwen 3.8-Flash-Next is not on Robin's named daily-driver stack** (Hermes / MiniMax-M3+H3 / OpenWiki / RAGFlow / NocoDB / SeaFile / Codex CLI are the named agents); (b) the established scope rule on non-named-stack open-weight LLM releases keeps them adjacent-not-promoted unless there is a direct change to Hermes / MiniMax / OpenWiki / Codex CLI itself (per the 2026-07-30 / 2026-08-03 / 2026-08-10 / 2026-08-12 / 2026-08-13 / 2026-08-15 / 2026-08-16 / 2026-08-17 / 2026-08-18 / 2026-08-19 / 2026-08-20 / 2026-08-21 / 2026-08-22 / 2026-08-23 / 2026-08-24 traceability entries); (c) the brief's "Workflow tooling priority LOW — surface story-worthy changes only" rule does not promote a 244-pt Qwen 3.8-Flash-Next model-card announcement to a `/themes.md` row by itself, though the **direct open-weight-LLM cross-walk to the `MiniMax-m3` row's V4-Flash-comparison anchor + the seventh open-weight-LLM-adjacent item in the streak + the strongest sustained engagement cluster in the streak** make this the strongest open-weight-LLM-adjacent item of the pull. Flagged for traceability because (a) the **244-pt engagement is the highest top-feed engagement on a non-Apple item of the pull**; (b) the **Qwen 3.8-Flash-Next model-card announcement** is the first Qwen-flash-family item since the 2026-08-23 Qwen 3.8 27B reverse-engineering item (`49407507` 234 pts); (c) the **open-weight-LLM cluster now totals 1,580+ pts across 6 items in the 2026-08-07 streak** (379 + 314 + 141 + 234 + 268 + 244 = 1,580 pts, the strongest sustained engagement cluster in the streak); (d) any future HN item at higher engagement combining Qwen 3.8-Flash-Next + explicit MiniMax-M3 / Hermes Agent / unsloth-MiniMax-M3-GGUF integration notes becomes the first corroborating event for a `MiniMax-m3-row-annex-open-weight-multimodal-parity` annex on the existing row. **No commitment row** — Qwen 3.8-Flash-Next is a vendor capability release announcement, not a vendor-stack change Robin acts on; the existing `MiniMax-m3` row is the canonical synthesis home. **No open-question row, no `/themes.md` row change** — `MiniMax-m3` stays at Last seen 2026-08-03 (no MiniMax model release; the Qwen announcement is upstream open-weight-LLM context, not a MiniMax-side change).
+- **49434291** (89 pts top) **"Anthropic tells staff to work from home due to possible security team strike"** — Business Insider (`DGAP` 2026-08-25, https://www.businessinsider.com/anthropic-san-francisco-staff-work-remote-office-security-strike-2026-8 — Business Insider). A Business Insider report on **Anthropic asking San Francisco staff to work from home due to a possible security team strike** — an Anthropic operational-distress signal. **Strongest AI-vendor-business-adjacent item of the pull by Anthropic operational-distress context** because (a) **89-pt top-feed engagement** is moderate — below the 100-pt vendor-release refresh bar but the highest Anthropic-operational-distress item in the 2026-08-07 streak; (b) the **Business Insider source** is a credible business-news outlet; (c) the **Anthropic operational-distress framing** (security team strike + WFH mandate) cross-walks to the broader Anthropic-competitive-pressure narrative that the 2026-08-24 FT Anthropic pricing-pressure essay (738 pts) already documented; (d) the **Anthropic-operational-distress framing** is the **first HN item since the 2026-08-13 `DeepSeek Harness` (422 pts)** to surface a specific Anthropic operational risk — the security team strike + WFH mandate is the first Anthropic-operational-distress item in the 2026-08-07 streak. **Adjacent-not-promoted** per scope because (a) **Anthropic operational distress is upstream-of-MiniMax competitive context, not a vendor-stack change Robin acts on**; (b) the established scope rule on non-named-stack AI-vendor business essays keeps them adjacent-not-promoted unless there is a direct change to Hermes / MiniMax / OpenWiki / Codex CLI itself (per the 2026-07-30 / 2026-08-03 / 2026-08-10 / 2026-08-12 / 2026-08-13 / 2026-08-15 / 2026-08-16 / 2026-08-17 / 2026-08-18 / 2026-08-19 / 2026-08-20 / 2026-08-21 / 2026-08-22 / 2026-08-23 / 2026-08-24 traceability entries); (c) the brief's "Workflow tooling priority LOW — surface story-worthy changes only" rule does not promote an 89-pt Anthropic-operational-distress item to a `/themes.md` row by itself, though the **direct AI-vendor-pricing + AI-vendor-operational cross-walk to the `MiniMax-m3` row's open-weight comparison anchor + the two-pull FT/BI cluster on AI-vendor governance + AI-vendor operational-distress** make this the strongest AI-vendor-business-adjacent item of the pull. Flagged because (a) the **direct AI-vendor-pricing + AI-vendor-operational cross-walk to the `MiniMax-m3` row** makes this a corroborating AI-vendor-business-stack signal alongside the 2026-08-24 FT Anthropic pricing-pressure essay + the 2026-08-19 Unsloth Dynamic 3.0 GGUFs + the 2026-07-29 MyClaw.ai MiniMax-M3 multimodal confirmation + the 2026-08-01 benchlm.ai DeepSeek V4 Flash vs MiniMax M3 comparison + the 2026-08-21 DeepSeek-v4-flash-vision release + the 2026-08-25 Qwen 3.8-Flash-Next announcement; (b) the **Anthropic-operational-distress framing** is a new operational risk dimension not previously surfaced in the streak; (c) any future HN item combining Anthropic / OpenAI operational distress + concrete open-weight vendor stability (e.g., Qwen / GLM / DeepSeek stability reports) becomes the first corroborating event for a `MiniMax-m3-row-annex-open-weight-vs-closed-weight-stability` annex on the existing row. **No commitment row** — Anthropic operational distress is upstream competitive context, not a vendor-stack change Robin acts on; the existing `MiniMax-m3` row is the canonical synthesis home. **No open-question row, no `/themes.md` row change** — `MiniMax-m3` stays at Last seen 2026-08-03 (no MiniMax model release; the Anthropic operational-distress item is upstream AI-vendor business context, not a MiniMax-side change).
+- **49437152** (15 pts top) **"Water Behind the Watts: The Hidden Risk of Powering Data Centers"** — Ceres report (`hn_acker` 2026-08-25, https://www.ceres.org/resources/reports/water-behind-the-watts-the-hidden-risk-of-powering-data-centers — Ceres, a sustainability-research non-profit). A Ceres report on **water-resource risk of data-center power consumption** — a sustainability/energy-resource analysis adjacent to the AI-inference + data-center-energy narrative. **Only data-center-energy-adjacent item on the 2026-08-25 top+best feed lane** because (a) the **Ceres source** is a credible sustainability-research non-profit source; (b) the **water-resource framing** is a new dimension not previously surfaced in the 2026-08-07 streak; (c) the **data-center-energy / AI-inference correlation** is implicit in the report (AI inference / training workloads are a primary driver of data-center power + water consumption). **Adjacent-not-promoted** per scope because (a) **15-pt engagement is well below the established refresh thresholds** (100-pt vendor-release / 50-pt clinical-translation / 21-pt OneCLI / 19-pt machine0 / 46-pt MCP Memory refresh triggers); (b) **data-center water-resource sustainability is not on Robin's named daily-driver stack or 4 application domains** (3D cell culture, 3D bioprinting, neuroscience in vitro, organoid workflows); (c) the established scope rule on non-named-stack / non-application-domain sustainability reports keeps them adjacent-not-promoted unless there is a direct change to the named stack or 4 application domains (per the 2026-08-20 Hubble-radiation-damage astronomy paper's "off-scope per scope discipline" precedent). Flagged because (a) it is the **only data-center-energy / AI-infrastructure-sustainability item on the 2026-08-25 top+best feed lane** — the first water-resource framing in the 2026-08-07 streak; (b) any future HN item at higher engagement combining data-center water / energy sustainability + AI-inference / training-workload context becomes the first corroborating event for a `class-organoid-3d-bioprinting` description extension on environmental sustainability evidence. **No commitment row, no open-question row, no `/themes.md` row change** — the data-center water-resource sustainability report is upstream environmental context, not a vendor-stack change Robin acts on.
+
+## Update — 2026-08-24 18:00 UTC
 
 - **Coverage:** 2 feeds (`top`, `best`), 6 search queries (the same simplified LLM-agent topic set from the source-specific instruction "Track organoid / CelVivo / 3Brain / Cellink / openwiki / AI agent stories": `organoid`, `CelVivo`, `3Brain`, `Cellink`, `openwiki`, `deepagents`). `top` feed had 30 IDs (28 resolved items), `best` feed had 30 IDs (15 resolved items); deduplication gave **38 unique items across both feeds** (5 overlap: `49419237` How Europe is killing makers 698 pts top+best, `49412396` I were 17 I'd learn LLMs from scratch 409 pts top+best, `49420873` Xiaomi CPU Apple-match 381 pts top+best, `49421158` MS Paint GUID watermark 214 pts top+best, `49415271` Executable Is a SQLite Database 368 pts top+best). The 6-query lane returned **fully-zero hits across all six Algolia queries** — `organoid` / `CelVivo` / `3Brain` / `Cellink` / `openwiki` / `deepagents` each returned `nbHits=0 / hits=0` in the 24 h window (the runtime payload on the 2026-08-24 pull reports clean integer `nbHits=0` rather than the `nbHits=null` shape on the 2026-08-21 + 2026-08-23 fully-zero pulls, but the `hits=0` array length confirms the same fully-zero lane; this is the **third consecutive shape-variant of fully-zero Algolia lane** across the 2026-08-21 / 2026-08-23 / 2026-08-24 pulls); the connector completed normally at `fetchedAt: 2026-08-24T18:00:28.191Z` (24-hour window).
 - **Life-science lane:** **zero vendor-anchored hits across all four named vendor queries — and zero substring-noise hits as well.** All four Algolia vendor queries (`organoid`, `CelVivo`, `3Brain`, `Cellink`) returned `hits=0` in the 24 h window, with no string-collision noise on `organi-` / `brain` / `calling` / `ceiling` / `helsinki` substrings (the 2026-08-22 pull surfaced 1 thematic + 4 noise on `organoid`, 1 thematic + 5 noise on `3Brain`, 3 noise on `Cellink`; the 2026-08-23 + 2026-08-24 pulls return to fully-zero across all four vendor queries — **two consecutive fully-zero Algolia lanes on all four vendor queries** for the most recent pulls, the first pair since 2026-08-08 / 2026-08-13 / 2026-08-15 / 2026-08-16 / 2026-08-18 / 2026-08-19 / 2026-08-21 + 2026-08-23). A title/URL regex sweep across the 38 unique top+best items also turned up **zero organoid / 3D-bioprinting / CelVivo / 3Brain / Cellink / ClinoStar / ClinoReactor / MEA / spheroid / organ-on-chip items** and **zero self-hosted agentic substrate cluster items** (the 6-item / 11-day cluster from DeepSeek Harness 2026-08-13 → machine0 2026-08-18 → OneCLI 2026-08-19 → self-hosted factory 2026-08-21 → Munder Difflin 2026-08-22 → "What Is a Harness?" 2026-08-23 has its first quiet pull on 2026-08-24 — **7 items in 12 days with one miss is still a strong cluster density**, the first quiet pull since the cluster started). The "no material HN footprint for the 4 vendor lines" finding continues to hold — this is the **fourteenth pull since 2026-08-07 with an empty / noise-only Algolia lane on vendor queries** (after the 2026-08-08 03:15 + 2026-08-08 18:00 + 2026-08-13 + 2026-08-15 + 2026-08-16 + 2026-08-18 + 2026-08-19 + 2026-08-21 + 2026-08-23 + 2026-08-24 fully-zero pulls + the 2026-08-10 + 2026-08-12 + 2026-08-17 + 2026-08-20 + 2026-08-22 noise-only pulls where vendor queries returned substring-fragment noise rather than fully zero; the 2026-08-24 pull is the **third consecutive fully-zero pull bookended with the noise-only 2026-08-22 pull** — three fully-zero Algolia lanes in four consecutive pulls — confirming that the empty-pulls-on-vendor-queries cadence is normal under the 6-query LLM-agent topic set, not an outage, no config-side intervention needed). The Tavily (web-search) lane remains the productive lane for vendor news; the HN lane's stable role is now "high-engagement inference-lane / agent-stack adjacents + low-engagement application-domain watchlist items + low-engagement self-hosted-agentic-substrate cluster essays" rather than vendor-direct signals. The 38 unique top+best items include **zero matches** for any in-scope vendor / customer / application-domain / named-stack keyword — no CelVivo / 3Brain / Cellink / ClinoStar / ClinoReactor / MEA / spheroid / organ-on-chip / organoid / bioprinting hits; no Hermes / OpenClaw / MiniMax / RAGFlow / NocoDB / SeaFile / Codex-CLI direct release hits. The single clinical-research-adjacent item on the pull is **`49415893` "FDA clears blood test to aid evaluation for Alzheimer's disease"** (154 pts top, 73 cmts, washu.edu — Alzheimer's / blood-test diagnostic; **adjacent-not-promoted** per scope because Alzheimer's is not one of Robin's 4 application domains — 3D cell culture, 3D bioprinting, neuroscience in vitro, organoid workflows — though Alzheimer's-diagnostic is a tangentially neuroscience-adjacent topic). Per the brief's "low-engagement items stay watchlist by default" rule + the `/themes.md` scope discipline, **none of the 38 unique items qualifies for a `/themes.md` row promotion on this pull**.

sources/index.md

@@ -4,7 +4,7 @@
 - [Agents 代理商档案索引 — 跨 agent CRM 同步](agents.md) - Cross-agent index of the Obsidian vault 02-Clients/Agents/* profiles (which agents Robin is actively working with, mapped by vendor product line). Base identity only — sensitive fields (phone / WeChat / email / end-customer list / opportunity value) live only in the private vault. Updated 2026-08-07 with _known_associations.md product-line → agent → end-customer mapping.
 - [全国经销商地图 (2026-08-07 时点)](distributors-china-2026.md) - Compact index of Robin's 2026-08-07 China distributor baseline (259 dealers across 7 regions, replacing 261 in the 2026-07-24 baseline) plus the new product-association index _known_associations.md. Surfaces CelVivo ClinoStar → 济南成全 + FemtoBiomed CellShot → 9X Bio → TriArm Therapeutics chain. Routes pricing-sensitive fields to the private Obsidian vault per /sources/agents.md privacy rule.
 - [飞书邮箱 (Robin customer mailbox)](feishu-mail.md) - Planned cross-agent mailbox sync target for Robin's Feishu (飞书) mailbox (imap.feishu.cn:993 / imap.larksuite.com:993) — would let MiniMax code / Hermes recall 'what did Robin last discuss with customer X' from email metadata + summaries. Not yet provisioned — IMAP credentials + update script + crontab still pending Robin setup; this page documents the planned configuration and the sync policy that will be applied once provisioned.
-- [Git repo — evidence index (Obsidian vault, Robin)](git-repo.md) - Compact manifest of Robin's Obsidian vault + the local OpenWiki wiki, ingested through the local git-repo connector. Two configured repos: obsidian-vault at /home/ldw/workspace (main branch, HEAD fb017e4f, 2026-08-23/24, **5 new vault commits in the 2026-08-23T18:11Z → 2026-08-24T18:05Z 24-hour window — the largest single-day LDR burst since the 2026-07-29 Parate / Lee / Hodge cluster: `ad4abcde` Ajongbolo 2025 Cells brain organoid review + `5f02489a` Kim 2025 Nat Commun EGaIn 3D MEA + `40b357b8` Tian 2025 Nat Commun hiPSC epicardium mTOR + `f2118a62` Aiello & Bagni 2025 biorxiv Rotating Chamber brain organoid CFD + `fb017e4f` CelVivo App Note 2026 ClinoStar vs orbital shaker — 3 CelVivo-aligned papers (App Note + Aiello + Ajongbolo mentions ClinoStar) + 1 3Brain-adjacent 3D-MEA competitor paper (Kim EGaIn) + 1 cardiac epicardium paper (Tian)**) and openwiki-wiki at /home/ldw/.openwiki/wiki (main branch, HEAD 127c2dc, 2026-08-24, **2 new automated wiki commits in the 2026-08-23T18:11Z → 2026-08-24T18:05Z window: `9cc5e63` daily update 2026-08-24 + `127c2dc` sources-sync 2026-08-24 — the tenth consecutive sources-sync re-applying the 2026-08-15 count-data wipe pattern**). This page is a navigation index — content ingestion (paper deep reads, sales scripts, customer files) happens via the Hermes skill and RAGFlow, not here.
+- [Git repo — evidence index (Obsidian vault, Robin)](git-repo.md) - Compact manifest of Robin's Obsidian vault + the local OpenWiki wiki, ingested through the local git-repo connector. Two configured repos: obsidian-vault at /home/ldw/workspace (main branch, HEAD 9d4767c7, 2026-08-25, **5 new vault commits in the 2026-08-24T18:05Z → 2026-08-25T18:13Z 24-hour window — the SECOND consecutive single-day 5-paper LDR cluster: `089177a7` Tevonian 2026 Nat Commun vascularized liver MPS + `583859a8` Yang 2026 Stem Cell Res Ther cardiac organoid review + `9aa2af4c` Update Tevonian 2026 + Yang 2026 (CelVivo/Cellink/Mimetas/3Brain/FemtoBiomed product mapping retrofit + 净化 Robin mentions — the first post-publish vendor-mapping retrofit on the 2026-08-23/24/25 LDR cluster) + `5907cdfc` Shen 2026 Chin Med J vascularized organoids review + `9d4767c7` Zhai 2026 Sci Adv 3D skin pemphigus — combined with the 2026-08-23/24 5-paper burst, **10 papers in 48 hours = the largest sustained 2-day research output in Robin's vault activity log; the burst creates 3 new deep-read subfolders: `Vascularized-Organoids/` (Tevonian + Shen) + `Cardiac-Organoids/` (Yang) + `Skin-Organoids/` (Zhai)**) and openwiki-wiki at /home/ldw/.openwiki/wiki (main branch, HEAD 1003b92, 2026-08-25, **2 new automated wiki commits in the 2026-08-24T18:05Z → 2026-08-25T18:13Z window: `3255613` daily update 2026-08-25 + `1003b92` sources-sync 2026-08-25 — the eleventh consecutive sources-sync re-applying the 2026-08-15 count-data wipe pattern**). This page is a navigation index — content ingestion (paper deep reads, sales scripts, customer files) happens via the Hermes skill and RAGFlow, not here.
 - [Hacker News — evidence index](hackernews.md) - Compact evidence trail for the Hacker News connector (hackernews-1, Robin-curated life-sciences + AI workflow). Synthesis lives on /themes.md, /commitments.md, etc.; this page only records ingestion coverage and notable items.
 - [文献精读 Master Template (Robin 7-27 实战版, "真适合浏览" 1 文件)](ldr-report-template.md) - Master template for Robin's literature-deep-read (LDR) pipeline — consolidates 4 literature skills (`literature-deep-read` / `research` / `review` / `curation-for-sales`) into a single 8-rule + 3-trigger + 5-section "真适合浏览" report format. Synthesized from 4-27 SOP范本 + 7-27 实战 lessons (Tasevska / Raji / Bosnjakovic). Triggers "精读吧" / "发 wikijs" / "入库" / "A" / Id/DOI/PMID/PDF signals into 4-step精简 or 8-step完整 flows. PDF全文必传 + PyMuPDF xref去重 + 9项强制 + SeaFile hostname `fb.biokingdom.top` + NocoDB v1 JSON + 3张真图 + `journal-year-topic` 报告路径.
 - [Bosnjakovic 2025 PAH 3D 球体代谢组学: 跟 CelVivo ClinoStar dynamic culture 关系 (Bosnjakovic 2025 bioRxiv)](literature-cel-bosnjakovic-2025-pah-deepread.md) - Deep-read synthesis of Bosnjakovic A et al. 2025 bioRxiv preprint (DOI 10.1101/2025.07.10.663939v1, 2025-07-10) — 21-day mature HepG2 3D spheroids with graded non-cytotoxic BaP + BBF (PAH代表物) exposure for metabolomics biomarker discovery. Robin's connection: 3D spheroid protocol maps directly onto CelVivo ClinoStar dynamic culture; supports PAH exposure metabolomics positioning for hepatotoxicity / NAFLD modeling applications. 精读 2026-07-27.

sources/literature.md

@@ -2,7 +2,8 @@
 type: "Reference"
 title: "Literature Deep-Reads — cross-agent deep-read index"
 description: "Cross-agent index of Robin's literature deep-reads across the 4 vendor product lines (CelVivo / 3Brain / Cellink / Femtobiomed) and adjacent application domains (organoid IRB / ethics, vascularized organoids, microfluidic / organ-on-chip). Backed by the Obsidian vault 04-Literature/Deep-Reads/ and the flywheel-sync pipeline; synthesis pages are linked per paper."
-tags: [literature, deep-read, flywheel, celvivo, 3brain, cellink, femtobiomed]
+tags: [literature, deep-read, flywheel, celvivo, 3brain, cellink, femtobiomed, tevonian-2026-vascularized-liver-mps, yang-2026-cardiac-organoid-review, shen-2026-vascularized-organoids-review, zhai-2026-3d-skin-pemphigus, 2026-08-25]
+timestamp: 2026-08-25T18:13:00Z
 ---
 
 # Literature Deep-Reads — cross-agent deep-read index
@@ -301,3 +302,37 @@ The `Robin_Picked_Papers` table is **new as of today** — created per Robin's 2
 - **主题**: CelVivo 官方 App Note — ClinoStar vs Orbital Shaker head-to-head 对比 HepG2/C3A + Caco-2 + 脑 organoid 三模型, 证明低剪切力优势跨细胞模型可复现
 - **配图**: 5 张 (Fig 1-5, MiniMax 限流未审) — v4 智能拼接 (xref bbox + caption 段)
 - **PDF**: NAS SMB fallback
+
+
+## 2026-08-25
+
+## Tevonian 2026 Nat Commun 血管化肝 MPS (PMID 41634021)
+- **DOI**: 10.1038/s41467-025-68031-6
+- **Path**: literature/tevonian-2026-nat-commun-vascularized-liver-mps
+- **Wiki ID**: 1749
+- **关键发现**: PDMS+fibrin+原代肝+HUVEC 血管化肝 MPS, 14天 IR 建模, 单核细胞浸润增强
+- **Robin 业务对接**: MASLD/NASH 体外建模 + 个性化药筛 + 血管化类器官平台
+
+
+## Yang 2026 Stem Cell Res Ther cardiac organoid review (PMID 41963991)
+- **DOI**: 10.1186/s13287-026-04996-5
+- **Path**: literature/yang-2026-stem-cell-res-ther-cardiac-organoid-review
+- **Wiki ID**: 1750
+- **关键发现**: 复旦 + InnoStar 综述从化学定义 hiPSC 到自组织心脏类器官的完整路径, 涵盖 FGF/PI3K/Wnt/BMP/Activin/RA 五大信号通路 + 三种 3D 培养策略
+- **Robin 业务对接**: 心脏药物毒性测试 + hiPSC 衍生心脏类器官服务 + 心血管疾病建模
+
+
+## Shen 2026 Chin Med J vascularized organoids review (PMID 42268296)
+- **DOI**: 10.1097/CM9.0000000000004136
+- **Path**: literature/shen-2026-cmj-vascularized-organoids
+- **Wiki ID**: 1751
+- **关键发现**: 华西医院综述血管化类器官 4 大策略(共培养 + 转录因子诱导 + 微流控 + 生物材料支架) + 12 维对比 + 三大未来方向
+- **Robin 业务对接**: 血管化类器官服务 + 多层血管网络平台 + 个性化精准医疗
+
+
+## Zhai 2026 Sci Adv 3D skin pemphigus (PMID 41512055)
+- **DOI**: 10.1126/sciadv.adz5003
+- **Path**: literature/zhai-2026-sciadv-3d-skin-pemphigus
+- **Wiki ID**: 1752
+- **关键发现**: 3D 打印 + 自组织多层血管化皮肤模型, 建模天疱疮自身免疫 + EGFR 靶向治疗 + ML 辅助药筛
+- **Robin 业务对接**: 皮肤自身免疫病药筛 + 3D 打印客户 + 精准医疗应用

sources/nocodb.md

@@ -1,3 +1,9 @@
+---
+type: "Reference"
+title: "NocoDB 文献库索引 — 跨 agent 数据层"
+openwiki_generated: true
+---
+
 # NocoDB 文献库索引 — 跨 agent 数据层
 
 > 数据源: NocoDB 13 个文献库 + 2 个公司库 (实时,每次 OpenWiki cron 跑时更新)

sources/ragflow.md

@@ -1,3 +1,9 @@
+---
+type: "Reference"
+title: "RAGFlow 全文检索索引 (Robin KB system)"
+openwiki_generated: true
+---
+
 # RAGFlow 全文检索索引 (Robin KB system)
 
 > 数据源: RAGFlow (http://10.10.10.254:9980/) 14 个 KB 全文检索结果

sources/seafile.md

@@ -1,3 +1,9 @@
+---
+type: "Reference"
+title: "SeaFile 大文件存储索引"
+openwiki_generated: true
+---
+
 # SeaFile 大文件存储索引
 
 > 数据源: SeaFile (http://10.10.10.254:9898/) 共 N 个资料库

sources/web-search.md

@@ -2,13 +2,21 @@
 type: "Reference"
 title: "Web Search Evidence"
 description: "Compact, source-backed evidence and ingestion coverage for the web-search-1 Tavily lane tracking CelVivo, 3Brain, Cellink, and related organoid news."
-tags: [source, web-search, tavily, celvivo, 3brain, cellink, organoids, 2026-08-12, 2026-08-15, 2026-08-16, 2026-08-17, 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, 2026-08-23, 2026-08-24]
-timestamp: 2026-08-24T18:04:19Z
+tags: [source, web-search, tavily, celvivo, 3brain, cellink, organoids, 2026-08-12, 2026-08-15, 2026-08-16, 2026-08-17, 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, 2026-08-23, 2026-08-24, 2026-08-25]
+timestamp: 2026-08-25T18:09:00Z
 ---
 
 # Web Search Evidence
 
-> Connector: `web-search-1` (Tavily). This page records compact, relevant evidence from Tavily pulls; search results are discovery leads, not vendor-confirmed announcements. Latest successful pull: 2026-08-03 18:08 UTC. The 2026-08-08, 2026-08-10, 2026-08-12, 2026-08-15, 2026-08-17, 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, 2026-08-23, and 2026-08-24 update attempts were skipped because the connector is disabled and `TAVILY_API_KEY` is not present; no new 24-hour evidence was available on any of these twelve runs.
+> Connector: `web-search-1` (Tavily). This page records compact, relevant evidence from Tavily pulls; search results are discovery leads, not vendor-confirmed announcements. Latest successful pull: 2026-08-03 18:08 UTC. The 2026-08-08, 2026-08-10, 2026-08-12, 2026-08-15, 2026-08-17, 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, 2026-08-23, 2026-08-24, and 2026-08-25 update attempts were skipped because the connector is disabled and `TAVILY_API_KEY` is not present; no new 24-hour evidence was available on any of these thirteen runs.
+
+## 2026-08-25 attempted update — skipped
+
+- **Status:** skipped. `web-search-1` is not enabled; the connector reports that `enabled=true` must be set in `~/.openwiki/connectors/web-search/config.json`.
+- **Authentication:** `TAVILY_API_KEY` is not present, so no Tavily request was made.
+- **Coverage:** no raw data files were written for this attempted 24-hour window. The nightly searxng-fallback slot (`~/.openwiki/connectors/web-search/raw/2026-08-24T18-35-03-searxng-fallback/`) is also empty (confirmed empty on disk — no files in the directory) — no web-search evidence of any kind landed in the 24-hour window. No new CelVivo, 3Brain, Cellink, or organoid findings were available for synthesis; the latest successful pull remains 2026-08-03 18:08 UTC.
+- **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md` from this source attempt.
+- **Operational note (cross-check):** the on-disk `~/.openwiki/connectors/web-search/config.json` does show `enabled: true` plus 6 Chinese-language queries (`CelVivo ClinoStar ClinoReactor 类器官培养新进展`, `3Brain HD-MEA 高密度微电极阵列 电生理`, `Cellink BIO X 3D生物打印 类器官`, `Femtobiomed CellShot 流式电转 精准医疗`, `类器官 vendor 2026年新发布`, `MiniMax M3 智能体 Hermes`). The agent runtime still reports the connector as disabled, so there is a discrepancy between disk config and runtime registry. This is an operational concern (connector enable / auth / re-registration), not a wiki-synthesis concern, and is recorded here for traceability rather than triggering wiki edits. The 2026-08-08, 2026-08-10, 2026-08-12, 2026-08-15, 2026-08-17, 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, 2026-08-23, and 2026-08-24 runs hit the same blocker; this is the **thirteenth consecutive skip on the same code path**. To resolve: set `TAVILY_API_KEY` in the OpenWiki runtime environment and ensure the runtime registry refreshes the connector's enabled state.
 
 ## 2026-08-24 attempted update — skipped
 
@@ -16,7 +24,7 @@ timestamp: 2026-08-24T18:04:19Z
 - **Authentication:** `TAVILY_API_KEY` is not present, so no Tavily request was made.
 - **Coverage:** no raw data files were written for this attempted 24-hour window. The nightly searxng-fallback slot (`~/.openwiki/connectors/web-search/raw/2026-08-23T18-35-03-searxng-fallback/`) is also empty (confirmed empty on disk — no files in the directory) — no web-search evidence of any kind landed in the 24-hour window. No new CelVivo, 3Brain, Cellink, or organoid findings were available for synthesis; the latest successful pull remains 2026-08-03 18:08 UTC.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md` from this source attempt.
-- **Operational note (cross-check):** the on-disk `~/.openwiki/connectors/web-search/config.json` does show `enabled: true` plus 6 Chinese-language queries (`CelVivo ClinoStar ClinoReactor 类器官培养新进展`, `3Brain HD-MEA 高密度微电极阵列 电生理`, `Cellink BIO X 3D生物打印 类器官`, `Femtobiomed CellShot 流式电转 精准医疗`, `类器官 vendor 2026年新发布`, `MiniMax M3 智能体 Hermes`). The agent runtime still reports the connector as disabled, so there is a discrepancy between disk config and runtime registry. This is an operational concern (connector enable / auth / re-registration), not a wiki-synthesis concern, and is recorded here for traceability rather than triggering wiki edits. The 2026-08-08, 2026-08-10, 2026-08-12, 2026-08-15, 2026-08-17, 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, and 2026-08-23 runs hit the same blocker; this is the **twelfth consecutive skip on the same code path**. To resolve: set `TAVILY_API_KEY` in the OpenWiki runtime environment and ensure the runtime registry refreshes the connector's enabled state.
+- **Operational note (cross-check):** the on-disk `~/.openwiki/connectors/web-search/config.json` does show `enabled: true` plus 6 Chinese-language queries (`CelVivo ClinoStar ClinoReactor 类器官培养新进展`, `3Brain HD-MEA 高密度微电极阵列 电生理`, `Cellink BIO X 3D生物打印 类器官`, `Femtobiomed CellShot 流式电转 精准医疗`, `类器官 vendor 2026年新发布`, `MiniMax M3 智能体 Hermes`). The agent runtime still reports the connector as disabled, so there is a discrepancy between disk config and runtime registry. This is an operational concern (connector enable / auth / re-registration), not a wiki-synthesis concern, and is recorded here for traceability rather than triggering wiki edits. The 2026-08-08, 2026-08-10, 2026-08-12, 2026-08-15, 2026-08-17, 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, and 2026-08-23 runs hit the same blocker; the 2026-08-25 run hit the same blocker too. This was the **twelfth consecutive skip on the same code path at the time of the 2026-08-24 attempt** (and the thirteenth skip including the 2026-08-25 follow-up). To resolve: set `TAVILY_API_KEY` in the OpenWiki runtime environment and ensure the runtime registry refreshes the connector's enabled state.
 
 ## 2026-08-23 attempted update — skipped
 
@@ -24,7 +32,7 @@ timestamp: 2026-08-24T18:04:19Z
 - **Authentication:** `TAVILY_API_KEY` is not present, so no Tavily request was made.
 - **Coverage:** no raw data files were written for this attempted 24-hour window. The nightly searxng-fallback slot (`~/.openwiki/connectors/web-search/raw/2026-08-22T18-35-04-searxng-fallback/`) is also empty (confirmed empty on disk — no files in the directory) — no web-search evidence of any kind landed in the 24-hour window. No new CelVivo, 3Brain, Cellink, or organoid findings were available for synthesis; the latest successful pull remains 2026-08-03 18:08 UTC.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md` from this source attempt.
-- **Operational note (cross-check):** the on-disk `~/.openwiki/connectors/web-search/config.json` does show `enabled: true` plus 6 Chinese-language queries (`CelVivo ClinoStar ClinoReactor 类器官培养新进展`, `3Brain HD-MEA 高密度微电极阵列 电生理`, `Cellink BIO X 3D生物打印 类器官`, `Femtobiomed CellShot 流式电转 精准医疗`, `类器官 vendor 2026年新发布`, `MiniMax M3 智能体 Hermes`). The agent runtime still reports the connector as disabled, so there is a discrepancy between disk config and runtime registry. This is an operational concern (connector enable / auth / re-registration), not a wiki-synthesis concern, and is recorded here for traceability rather than triggering wiki edits. The 2026-08-08, 2026-08-10, 2026-08-12, 2026-08-15, 2026-08-17, 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, and 2026-08-22 runs hit the same blocker; this is the **eleventh consecutive skip on the same code path**. To resolve: set `TAVILY_API_KEY` in the OpenWiki runtime environment and ensure the runtime registry refreshes the connector's enabled state.
+- **Operational note (cross-check):** the on-disk `~/.openwiki/connectors/web-search/config.json` does show `enabled: true` plus 6 Chinese-language queries (`CelVivo ClinoStar ClinoReactor 类器官培养新进展`, `3Brain HD-MEA 高密度微电极阵列 电生理`, `Cellink BIO X 3D生物打印 类器官`, `Femtobiomed CellShot 流式电转 精准医疗`, `类器官 vendor 2026年新发布`, `MiniMax M3 智能体 Hermes`). The agent runtime still reports the connector as disabled, so there is a discrepancy between disk config and runtime registry. This is an operational concern (connector enable / auth / re-registration), not a wiki-synthesis concern, and is recorded here for traceability rather than triggering wiki edits. The 2026-08-08, 2026-08-10, 2026-08-12, 2026-08-15, 2026-08-17, 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, and 2026-08-22 runs hit the same blocker; the 2026-08-24 and 2026-08-25 runs hit the same blocker too. This was the **eleventh consecutive skip on the same code path at the time of the 2026-08-23 attempt** (and the thirteenth skip including the 2026-08-24 + 2026-08-25 follow-ups). To resolve: set `TAVILY_API_KEY` in the OpenWiki runtime environment and ensure the runtime registry refreshes the connector's enabled state.
 
 ## 2026-08-22 attempted update — skipped
 
@@ -32,7 +40,7 @@ timestamp: 2026-08-24T18:04:19Z
 - **Authentication:** `TAVILY_API_KEY` is not present, so no Tavily request was made.
 - **Coverage:** no raw data files were written for this attempted 24-hour window. The nightly searxng-fallback slot (`~/.openwiki/connectors/web-search/raw/2026-08-21T18-35-04-searxng-fallback/`) is also empty (confirmed empty on disk) — no web-search evidence of any kind landed in the 24-hour window. No new CelVivo, 3Brain, Cellink, or organoid findings were available for synthesis; the latest successful pull remains 2026-08-03 18:08 UTC.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md` from this source attempt.
-- **Operational note (cross-check):** the on-disk `~/.openwiki/connectors/web-search/config.json` does show `enabled: true` plus 6 Chinese-language queries (`CelVivo ClinoStar ClinoReactor 类器官培养新进展`, `3Brain HD-MEA 高密度微电极阵列 电生理`, `Cellink BIO X 3D生物打印 类器官`, `Femtobiomed CellShot 流式电转 精准医疗`, `类器官 vendor 2026年新发布`, `MiniMax M3 智能体 Hermes`). The agent runtime still reports the connector as disabled, so there is a discrepancy between disk config and runtime registry. This is an operational concern (connector enable / auth / re-registration), not a wiki-synthesis concern, and is recorded here for traceability rather than triggering wiki edits. The 2026-08-08, 2026-08-10, 2026-08-12, 2026-08-15, 2026-08-17, 2026-08-18, 2026-08-19, 2026-08-20, and 2026-08-21 runs hit the same blocker; the 2026-08-23 run hit the same blocker too. This was the **tenth consecutive skip on the same code path at the time of the 2026-08-22 attempt** (and the eleventh skip including the 2026-08-23 follow-up). To resolve: set `TAVILY_API_KEY` in the OpenWiki runtime environment and ensure the runtime registry refreshes the connector's enabled state.
+- **Operational note (cross-check):** the on-disk `~/.openwiki/connectors/web-search/config.json` does show `enabled: true` plus 6 Chinese-language queries (`CelVivo ClinoStar ClinoReactor 类器官培养新进展`, `3Brain HD-MEA 高密度微电极阵列 电生理`, `Cellink BIO X 3D生物打印 类器官`, `Femtobiomed CellShot 流式电转 精准医疗`, `类器官 vendor 2026年新发布`, `MiniMax M3 智能体 Hermes`). The agent runtime still reports the connector as disabled, so there is a discrepancy between disk config and runtime registry. This is an operational concern (connector enable / auth / re-registration), not a wiki-synthesis concern, and is recorded here for traceability rather than triggering wiki edits. The 2026-08-08, 2026-08-10, 2026-08-12, 2026-08-15, 2026-08-17, 2026-08-18, 2026-08-19, 2026-08-20, and 2026-08-21 runs hit the same blocker; the 2026-08-23 + 2026-08-24 + 2026-08-25 runs hit the same blocker too. This was the **tenth consecutive skip on the same code path at the time of the 2026-08-22 attempt** (and the thirteenth skip including the 2026-08-23 + 2026-08-24 + 2026-08-25 follow-ups). To resolve: set `TAVILY_API_KEY` in the OpenWiki runtime environment and ensure the runtime registry refreshes the connector's enabled state.
 
 ## 2026-08-21 attempted update — skipped
 
@@ -40,7 +48,7 @@ timestamp: 2026-08-24T18:04:19Z
 - **Authentication:** `TAVILY_API_KEY` is not present, so no Tavily request was made.
 - **Coverage:** no raw data files were written for this attempted 24-hour window. The nightly searxng-fallback slot (`~/.openwiki/connectors/web-search/raw/2026-08-20T18-35-03-searxng-fallback/`) is also empty (confirmed empty on disk) — no web-search evidence of any kind landed in the 24-hour window. No new CelVivo, 3Brain, Cellink, or organoid findings were available for synthesis; the latest successful pull remains 2026-08-03 18:08 UTC.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md` from this source attempt.
-- **Operational note (cross-check):** the on-disk `~/.openwiki/connectors/web-search/config.json` does show `enabled: true` plus 6 Chinese-language queries (`CelVivo ClinoStar ClinoReactor 类器官培养新进展`, `3Brain HD-MEA 高密度微电极阵列 电生理`, `Cellink BIO X 3D生物打印 类器官`, `Femtobiomed CellShot 流式电转 精准医疗`, `类器官 vendor 2026年新发布`, `MiniMax M3 智能体 Hermes`). The agent runtime still reports the connector as disabled, so there is a discrepancy between disk config and runtime registry. This is an operational concern (connector enable / auth / re-registration), not a wiki-synthesis concern, and is recorded here for traceability rather than triggering wiki edits. The 2026-08-08, 2026-08-10, 2026-08-12, 2026-08-15, 2026-08-17, 2026-08-18, 2026-08-19, and 2026-08-20 runs hit the same blocker; the 2026-08-22 + 2026-08-23 runs hit the same blocker too. This was the **ninth consecutive skip on the same code path at the time of the 2026-08-21 attempt** (and the eleventh skip including the 2026-08-22 + 2026-08-23 follow-ups). To resolve: set `TAVILY_API_KEY` in the OpenWiki runtime environment and ensure the runtime registry refreshes the connector's enabled state.
+- **Operational note (cross-check):** the on-disk `~/.openwiki/connectors/web-search/config.json` does show `enabled: true` plus 6 Chinese-language queries (`CelVivo ClinoStar ClinoReactor 类器官培养新进展`, `3Brain HD-MEA 高密度微电极阵列 电生理`, `Cellink BIO X 3D生物打印 类器官`, `Femtobiomed CellShot 流式电转 精准医疗`, `类器官 vendor 2026年新发布`, `MiniMax M3 智能体 Hermes`). The agent runtime still reports the connector as disabled, so there is a discrepancy between disk config and runtime registry. This is an operational concern (connector enable / auth / re-registration), not a wiki-synthesis concern, and is recorded here for traceability rather than triggering wiki edits. The 2026-08-08, 2026-08-10, 2026-08-12, 2026-08-15, 2026-08-17, 2026-08-18, 2026-08-19, and 2026-08-20 runs hit the same blocker; the 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 runs hit the same blocker too. This was the **ninth consecutive skip on the same code path at the time of the 2026-08-21 attempt** (and the thirteenth skip including the 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 follow-ups). To resolve: set `TAVILY_API_KEY` in the OpenWiki runtime environment and ensure the runtime registry refreshes the connector's enabled state.
 
 ## 2026-08-20 attempted update — skipped
 
@@ -48,7 +56,7 @@ timestamp: 2026-08-24T18:04:19Z
 - **Authentication:** `TAVILY_API_KEY` is not present, so no Tavily request was made.
 - **Coverage:** no raw data files were written for this attempted 24-hour window. The nightly searxng-fallback slot (`~/.openwiki/connectors/web-search/raw/2026-08-19T18-35-03-searxng-fallback/`) is also empty — no web-search evidence of any kind landed in the 24-hour window. No new CelVivo, 3Brain, Cellink, or organoid findings were available for synthesis; the latest successful pull remains 2026-08-03 18:08 UTC.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md` from this source attempt.
-- **Operational note (cross-check):** the on-disk `~/.openwiki/connectors/web-search/config.json` does show `enabled: true` plus 6 Chinese-language queries (`CelVivo ClinoStar ClinoReactor 类器官培养新进展`, `3Brain HD-MEA 高密度微电极阵列 电生理`, `Cellink BIO X 3D生物打印 类器官`, `Femtobiomed CellShot 流式电转 精准医疗`, `类器官 vendor 2026年新发布`, `MiniMax M3 智能体 Hermes`). The agent runtime still reports the connector as disabled, so there is a discrepancy between disk config and runtime registry. This is an operational concern (connector enable / auth / re-registration), not a wiki-synthesis concern, and is recorded here for traceability rather than triggering wiki edits. The 2026-08-08, 2026-08-10, 2026-08-12, 2026-08-15, 2026-08-17, 2026-08-18, and 2026-08-19 runs hit the same blocker; the 2026-08-21 + 2026-08-22 + 2026-08-23 runs hit the same blocker too. This was the **eighth consecutive skip on the same code path at the time of the 2026-08-20 attempt** (and the eleventh skip including the 2026-08-21 + 2026-08-22 + 2026-08-23 follow-ups). To resolve: set `TAVILY_API_KEY` in the OpenWiki runtime environment and ensure the runtime registry refreshes the connector's enabled state.
+- **Operational note (cross-check):** the on-disk `~/.openwiki/connectors/web-search/config.json` does show `enabled: true` plus 6 Chinese-language queries (`CelVivo ClinoStar ClinoReactor 类器官培养新进展`, `3Brain HD-MEA 高密度微电极阵列 电生理`, `Cellink BIO X 3D生物打印 类器官`, `Femtobiomed CellShot 流式电转 精准医疗`, `类器官 vendor 2026年新发布`, `MiniMax M3 智能体 Hermes`). The agent runtime still reports the connector as disabled, so there is a discrepancy between disk config and runtime registry. This is an operational concern (connector enable / auth / re-registration), not a wiki-synthesis concern, and is recorded here for traceability rather than triggering wiki edits. The 2026-08-08, 2026-08-10, 2026-08-12, 2026-08-15, 2026-08-17, 2026-08-18, and 2026-08-19 runs hit the same blocker; the 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 runs hit the same blocker too. This was the **eighth consecutive skip on the same code path at the time of the 2026-08-20 attempt** (and the thirteenth skip including the 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 follow-ups). To resolve: set `TAVILY_API_KEY` in the OpenWiki runtime environment and ensure the runtime registry refreshes the connector's enabled state.
 
 ## 2026-08-19 attempted update — skipped
 
@@ -56,7 +64,7 @@ timestamp: 2026-08-24T18:04:19Z
 - **Authentication:** `TAVILY_API_KEY` is not present, so no Tavily request was made.
 - **Coverage:** no raw data files were written for this attempted 24-hour window. The nightly searxng-fallback slot (`~/.openwiki/connectors/web-search/raw/2026-08-18T18-35-03-searxng-fallback/`) is also empty — no web-search evidence of any kind landed in the 24-hour window. No new CelVivo, 3Brain, Cellink, or organoid findings were available for synthesis; the latest successful pull remains 2026-08-03 18:08 UTC.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md` from this source attempt.
-- **Operational note (cross-check):** the on-disk `~/.openwiki/connectors/web-search/config.json` does show `enabled: true` plus 6 Chinese-language queries (`CelVivo ClinoStar ClinoReactor 类器官培养新进展`, `3Brain HD-MEA 高密度微电极阵列 电生理`, `Cellink BIO X 3D生物打印 类器官`, `Femtobiomed CellShot 流式电转 精准医疗`, `类器官 vendor 2026年新发布`, `MiniMax M3 智能体 Hermes`). The agent runtime still reports the connector as disabled, so there is a discrepancy between disk config and runtime registry. This is an operational concern (connector enable / auth / re-registration), not a wiki-synthesis concern, and is recorded here for traceability rather than triggering wiki edits. The 2026-08-08, 2026-08-10, 2026-08-12, 2026-08-15, 2026-08-17, and 2026-08-18 runs hit the same blocker; the 2026-08-20, 2026-08-21, 2026-08-22, and 2026-08-23 runs hit the same blocker too. This was the **seventh consecutive skip on the same code path at the time of the 2026-08-19 attempt** (and the eleventh skip including the 2026-08-20, 2026-08-21, 2026-08-22, and 2026-08-23 follow-ups). To resolve: set `TAVILY_API_KEY` in the OpenWiki runtime environment and ensure the runtime registry refreshes the connector's enabled state.
+- **Operational note (cross-check):** the on-disk `~/.openwiki/connectors/web-search/config.json` does show `enabled: true` plus 6 Chinese-language queries (`CelVivo ClinoStar ClinoReactor 类器官培养新进展`, `3Brain HD-MEA 高密度微电极阵列 电生理`, `Cellink BIO X 3D生物打印 类器官`, `Femtobiomed CellShot 流式电转 精准医疗`, `类器官 vendor 2026年新发布`, `MiniMax M3 智能体 Hermes`). The agent runtime still reports the connector as disabled, so there is a discrepancy between disk config and runtime registry. This is an operational concern (connector enable / auth / re-registration), not a wiki-synthesis concern, and is recorded here for traceability rather than triggering wiki edits. The 2026-08-08, 2026-08-10, 2026-08-12, 2026-08-15, 2026-08-17, and 2026-08-18 runs hit the same blocker; the 2026-08-20, 2026-08-21, 2026-08-22, 2026-08-23, 2026-08-24, and 2026-08-25 runs hit the same blocker too. This was the **seventh consecutive skip on the same code path at the time of the 2026-08-19 attempt** (and the thirteenth skip including the 2026-08-20, 2026-08-21, 2026-08-22, 2026-08-23, 2026-08-24, and 2026-08-25 follow-ups). To resolve: set `TAVILY_API_KEY` in the OpenWiki runtime environment and ensure the runtime registry refreshes the connector's enabled state.
 
 ## 2026-08-18 attempted update — skipped
 
@@ -64,7 +72,7 @@ timestamp: 2026-08-24T18:04:19Z
 - **Authentication:** `TAVILY_API_KEY` is not present, so no Tavily request was made.
 - **Coverage:** no raw data files were written for this attempted 24-hour window. The nightly searxng-fallback slot (`~/.openwiki/connectors/web-search/raw/2026-08-17T18-35-03-searxng-fallback/`) is also empty — no web-search evidence of any kind landed in the 24-hour window. No new CelVivo, 3Brain, Cellink, or organoid findings were available for synthesis; the latest successful pull remains 2026-08-03 18:08 UTC.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md` from this source attempt.
-- **Operational note (cross-check):** the on-disk `~/.openwiki/connectors/web-search/config.json` does show `enabled: true` plus 6 Chinese-language queries (`CelVivo ClinoStar ClinoReactor 类器官培养新进展`, `3Brain HD-MEA 高密度微电极阵列 电生理`, `Cellink BIO X 3D生物打印 类器官`, `Femtobiomed CellShot 流式电转 精准医疗`, `类器官 vendor 2026年新发布`, `MiniMax M3 智能体 Hermes`). The agent runtime still reports the connector as disabled, so there is a discrepancy between disk config and runtime registry. This is an operational concern (connector enable / auth / re-registration), not a wiki-synthesis concern, and is recorded here for traceability rather than triggering wiki edits. The 2026-08-08, 2026-08-10, 2026-08-12, 2026-08-15, and 2026-08-17 runs hit the same blocker; the 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, and 2026-08-23 runs hit the same blocker too. This was the **sixth consecutive skip on the same code path at the time of the 2026-08-18 attempt** (and the eleventh skip including the 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, and 2026-08-23 follow-ups).
+- **Operational note (cross-check):** the on-disk `~/.openwiki/connectors/web-search/config.json` does show `enabled: true` plus 6 Chinese-language queries (`CelVivo ClinoStar ClinoReactor 类器官培养新进展`, `3Brain HD-MEA 高密度微电极阵列 电生理`, `Cellink BIO X 3D生物打印 类器官`, `Femtobiomed CellShot 流式电转 精准医疗`, `类器官 vendor 2026年新发布`, `MiniMax M3 智能体 Hermes`). The agent runtime still reports the connector as disabled, so there is a discrepancy between disk config and runtime registry. This is an operational concern (connector enable / auth / re-registration), not a wiki-synthesis concern, and is recorded here for traceability rather than triggering wiki edits. The 2026-08-08, 2026-08-10, 2026-08-12, 2026-08-15, and 2026-08-17 runs hit the same blocker; the 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, 2026-08-23, 2026-08-24, and 2026-08-25 runs hit the same blocker too. This was the **sixth consecutive skip on the same code path at the time of the 2026-08-18 attempt** (and the thirteenth skip including the 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, 2026-08-23, 2026-08-24, and 2026-08-25 follow-ups).
 
 ## 2026-08-17 attempted update — skipped
 
@@ -72,7 +80,7 @@ timestamp: 2026-08-24T18:04:19Z
 - **Authentication:** `TAVILY_API_KEY` is not present, so no Tavily request was made.
 - **Coverage:** no raw data files were written for this attempted 24-hour window. The nightly searxng-fallback slot (`~/.openwiki/connectors/web-search/raw/2026-08-16T18-35-03-searxng-fallback/`) is also empty — no web-search evidence of any kind landed in the 24-hour window. No new CelVivo, 3Brain, Cellink, or organoid findings were available for synthesis; the latest successful pull remains 2026-08-03 18:08 UTC.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md` from this source attempt.
-- **Operational note (cross-check):** the on-disk `~/.openwiki/connectors/web-search/config.json` does show `enabled: true` plus 6 Chinese-language queries (`CelVivo ClinoStar ClinoReactor 类器官培养新进展`, `3Brain HD-MEA 高密度微电极阵列 电生理`, `Cellink BIO X 3D生物打印 类器官`, `Femtobiomed CellShot 流式电转 精准医疗`, `类器官 vendor 2026年新发布`, `MiniMax M3 智能体 Hermes`). The agent runtime still reports the connector as disabled, so there is a discrepancy between disk config and runtime registry. This is an operational concern (connector enable / auth / re-registration), not a wiki-synthesis concern, and is recorded here for traceability rather than triggering wiki edits. The 2026-08-08, 2026-08-10, 2026-08-12, and 2026-08-15 runs hit the same blocker; the 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, and 2026-08-23 runs hit the same blocker too. This was the **fifth consecutive skip on the same code path at the time of the 2026-08-17 attempt** (and the eleventh skip including the 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, and 2026-08-23 follow-ups).
+- **Operational note (cross-check):** the on-disk `~/.openwiki/connectors/web-search/config.json` does show `enabled: true` plus 6 Chinese-language queries (`CelVivo ClinoStar ClinoReactor 类器官培养新进展`, `3Brain HD-MEA 高密度微电极阵列 电生理`, `Cellink BIO X 3D生物打印 类器官`, `Femtobiomed CellShot 流式电转 精准医疗`, `类器官 vendor 2026年新发布`, `MiniMax M3 智能体 Hermes`). The agent runtime still reports the connector as disabled, so there is a discrepancy between disk config and runtime registry. This is an operational concern (connector enable / auth / re-registration), not a wiki-synthesis concern, and is recorded here for traceability rather than triggering wiki edits. The 2026-08-08, 2026-08-10, 2026-08-12, and 2026-08-15 runs hit the same blocker; the 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, 2026-08-23, 2026-08-24, and 2026-08-25 runs hit the same blocker too. This was the **fifth consecutive skip on the same code path at the time of the 2026-08-17 attempt** (and the thirteenth skip including the 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, 2026-08-23, 2026-08-24, and 2026-08-25 follow-ups).
 
 ## 2026-08-15 attempted update — skipped
 
@@ -80,7 +88,7 @@ timestamp: 2026-08-24T18:04:19Z
 - **Authentication:** `TAVILY_API_KEY` is not present, so no Tavily request was made.
 - **Coverage:** no raw data files were written for this attempted 24-hour window. No new CelVivo, 3Brain, Cellink, or organoid findings were available for synthesis; the latest successful pull remains 2026-08-03 18:08 UTC.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md` from this source attempt.
-- **Operational note (cross-check):** the on-disk `~/.openwiki/connectors/web-search/config.json` does show `enabled: true` plus 6 Chinese-language queries (`CelVivo ClinoStar ClinoReactor 类器官培养新进展`, `3Brain HD-MEA 高密度微电极阵列 电生理`, `Cellink BIO X 3D生物打印 类器官`, `Femtobiomed CellShot 流式电转 精准医疗`, `类器官 vendor 2026年新发布`, `MiniMax M3 智能体 Hermes`). The agent runtime still reports the connector as disabled, so there is a discrepancy between disk config and runtime registry. This is an operational concern (connector enable / auth / re-registration), not a wiki-synthesis concern, and is recorded here for traceability rather than triggering wiki edits. The 2026-08-08, 2026-08-10, and 2026-08-12 runs hit the same blocker; the 2026-08-17, 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, and 2026-08-23 runs hit the same blocker too. This was the fourth consecutive skip on the same code path at the time of the 2026-08-15 attempt (and the eleventh skip including the 2026-08-17, 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, and 2026-08-23 follow-ups).
+- **Operational note (cross-check):** the on-disk `~/.openwiki/connectors/web-search/config.json` does show `enabled: true` plus 6 Chinese-language queries (`CelVivo ClinoStar ClinoReactor 类器官培养新进展`, `3Brain HD-MEA 高密度微电极阵列 电生理`, `Cellink BIO X 3D生物打印 类器官`, `Femtobiomed CellShot 流式电转 精准医疗`, `类器官 vendor 2026年新发布`, `MiniMax M3 智能体 Hermes`). The agent runtime still reports the connector as disabled, so there is a discrepancy between disk config and runtime registry. This is an operational concern (connector enable / auth / re-registration), not a wiki-synthesis concern, and is recorded here for traceability rather than triggering wiki edits. The 2026-08-08, 2026-08-10, and 2026-08-12 runs hit the same blocker; the 2026-08-17, 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, 2026-08-23, 2026-08-24, and 2026-08-25 runs hit the same blocker too. This was the fourth consecutive skip on the same code path at the time of the 2026-08-15 attempt (and the thirteenth skip including the 2026-08-17, 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, 2026-08-23, 2026-08-24, and 2026-08-25 follow-ups).
 
 ## 2026-08-12 attempted update — skipped
 
@@ -88,7 +96,7 @@ timestamp: 2026-08-24T18:04:19Z
 - **Authentication:** `TAVILY_API_KEY` is not present, so no Tavily request was made.
 - **Coverage:** no raw data files were written for this attempted 24-hour window. No new CelVivo, 3Brain, Cellink, or organoid findings were available for synthesis; the latest successful pull remains 2026-08-03 18:08 UTC.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md` from this source attempt.
-- **Operational note (cross-check):** the on-disk `~/.openwiki/connectors/web-search/config.json` does show `enabled: true` plus 6 Chinese-language queries (`CelVivo ClinoStar ClinoReactor 类器官培养新进展`, `3Brain HD-MEA 高密度微电极阵列 电生理`, `Cellink BIO X 3D生物打印 类器官`, `Femtobiomed CellShot 流式电转 精准医疗`, `类器官 vendor 2026年新发布`, `MiniMax M3 智能体 Hermes`). The agent runtime still reports the connector as disabled, so there is a discrepancy between disk config and runtime registry. This is an operational concern (connector enable / auth / re-registration), not a wiki-synthesis concern, and is recorded here for traceability rather than triggering wiki edits. The 2026-08-08 and 2026-08-10 runs hit the same blocker; this is the third consecutive skip on the same code path.
+- **Operational note (cross-check):** the on-disk `~/.openwiki/connectors/web-search/config.json` does show `enabled: true` plus 6 Chinese-language queries (`CelVivo ClinoStar ClinoReactor 类器官培养新进展`, `3Brain HD-MEA 高密度微电极阵列 电生理`, `Cellink BIO X 3D生物打印 类器官`, `Femtobiomed CellShot 流式电转 精准医疗`, `类器官 vendor 2026年新发布`, `MiniMax M3 智能体 Hermes`). The agent runtime still reports the connector as disabled, so there is a discrepancy between disk config and runtime registry. This is an operational concern (connector enable / auth / re-registration), not a wiki-synthesis concern, and is recorded here for traceability rather than triggering wiki edits. The 2026-08-08 and 2026-08-10 runs hit the same blocker; the 2026-08-15, 2026-08-17, 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, 2026-08-23, 2026-08-24, and 2026-08-25 runs hit the same blocker too. This was the third consecutive skip on the same code path at the time of the 2026-08-12 attempt (and the thirteenth skip including the 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 follow-ups).
 
 ## 2026-08-10 attempted update — skipped
 
@@ -96,7 +104,7 @@ timestamp: 2026-08-24T18:04:19Z
 - **Authentication:** `TAVILY_API_KEY` is not present, so no Tavily request was made.
 - **Coverage:** no raw data files were written for this attempted 24-hour window. No new CelVivo, 3Brain, Cellink, or organoid findings were available for synthesis; the latest successful pull remains 2026-08-03 18:08 UTC.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md` from this source attempt.
-- **Operational note (cross-check):** the on-disk `~/.openwiki/connectors/web-search/config.json` does show `enabled: true` plus 6 Chinese-language queries (`CelVivo ClinoStar ClinoReactor 类器官培养新进展`, `3Brain HD-MEA 高密度微电极阵列 电生理`, `Cellink BIO X 3D生物打印 类器官`, `Femtobiomed CellShot 流式电转 精准医疗`, `类器官 vendor 2026年新发布`, `MiniMax M3 智能体 Hermes`). The agent runtime still reports the connector as disabled, so there is a discrepancy between disk config and runtime registry. This is an operational concern (connector enable / auth / re-registration), not a wiki-synthesis concern, and is recorded here for traceability rather than triggering wiki edits.
+- **Operational note (cross-check):** the on-disk `~/.openwiki/connectors/web-search/config.json` does show `enabled: true` plus 6 Chinese-language queries (`CelVivo ClinoStar ClinoReactor 类器官培养新进展`, `3Brain HD-MEA 高密度微电极阵列 电生理`, `Cellink BIO X 3D生物打印 类器官`, `Femtobiomed CellShot 流式电转 精准医疗`, `类器官 vendor 2026年新发布`, `MiniMax M3 智能体 Hermes`). The agent runtime still reports the connector as disabled, so there is a discrepancy between disk config and runtime registry. This is an operational concern (connector enable / auth / re-registration), not a wiki-synthesis concern, and is recorded here for traceability rather than triggering wiki edits. The 2026-08-08 run hit the same blocker; the 2026-08-12, 2026-08-15, 2026-08-17, 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, 2026-08-23, 2026-08-24, and 2026-08-25 runs hit the same blocker too. This was the second consecutive skip on the same code path at the time of the 2026-08-10 attempt (and the thirteenth skip including the 2026-08-12 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 follow-ups).
 
 ## 2026-08-08 attempted update — skipped
 
@@ -104,6 +112,7 @@ timestamp: 2026-08-24T18:04:19Z
 - **Authentication:** `TAVILY_API_KEY` is not present, so no Tavily request was made.
 - **Coverage:** no raw data files were written for this attempted 24-hour window. No new CelVivo, 3Brain, Cellink, or organoid findings were available for synthesis; the latest successful pull remains 2026-08-03 18:08 UTC.
 - **Synthesis:** no changes were made to `/themes.md`, `/commitments.md`, `/open-questions.md`, or `/personal-logistics.md` from this source attempt.
+- **Operational note (cross-check):** the on-disk `~/.openwiki/connectors/web-search/config.json` does show `enabled: true` plus 6 Chinese-language queries (`CelVivo ClinoStar ClinoReactor 类器官培养新进展`, `3Brain HD-MEA 高密度微电极阵列 电生理`, `Cellink BIO X 3D生物打印 类器官`, `Femtobiomed CellShot 流式电转 精准医疗`, `类器官 vendor 2026年新发布`, `MiniMax M3 智能体 Hermes`). The agent runtime still reports the connector as disabled, so there is a discrepancy between disk config and runtime registry. This is an operational concern (connector enable / auth / re-registration), not a wiki-synthesis concern, and is recorded here for traceability rather than triggering wiki edits. The 2026-08-10, 2026-08-12, 2026-08-15, 2026-08-17, 2026-08-18, 2026-08-19, 2026-08-20, 2026-08-21, 2026-08-22, 2026-08-23, 2026-08-24, and 2026-08-25 runs hit the same blocker too. This was the first skip on the same code path (and the thirteenth skip including the 2026-08-10 + 2026-08-12 + 2026-08-15 + 2026-08-17 + 2026-08-18 + 2026-08-19 + 2026-08-20 + 2026-08-21 + 2026-08-22 + 2026-08-23 + 2026-08-24 + 2026-08-25 follow-ups).
 
 ## Historical successful pulls
 

sources/wikijs.md

@@ -1,3 +1,9 @@
+---
+type: "Reference"
+title: "Wiki.js 索引 — 跨 agent 文档发布层"
+openwiki_generated: true
+---
+
 # Wiki.js 索引 — 跨 agent 文档发布层
 
 > 数据源: Wiki.js (http://10.10.10.254:3000/graphql) Biokingdom 实例

themes/05-robin-research.md

@@ -2,8 +2,8 @@
 type: "Reference"
 title: "Theme 5 · Robin's personal research (vendor deep reads + sales ammunition + CRM)"
 description: "Synthesis page for Robin's personal research portfolio — Obsidian vault + literature deep-read pipeline + sales ammunition + China distributor map + active CRM profiles + work-rhythm snapshots. Output routes into vendor themes 01 (organoid-equipment) and 02 (bioprinting). The 2026-08-23/24 fetch surfaced the largest single-day LDR burst since 2026-07-29 — 5 papers committed to main + new `deepread_40240593/` pipeline workspace directory."
-tags: [theme, research, vault, deep-read, sales, crm, life-sciences, 2026-08-24, 2026-08-23, 2026-08-22, 2026-08-21, 2026-08-20, 2026-08-19, 2026-08-18, 2026-08-17, 2026-08-15, 2026-08-13, celvivo-app-note-2026, aiello-bagni-rc-cfd, tian-epicardium-mtor, kim-egain-3d-mea, ajongbolo-brain-organoid-review]
-timestamp: 2026-08-24T18:05:00Z
+tags: [theme, research, vault, deep-read, sales, crm, life-sciences, 2026-08-25, 2026-08-24, 2026-08-23, 2026-08-22, 2026-08-21, 2026-08-20, 2026-08-19, 2026-08-18, 2026-08-17, 2026-08-15, 2026-08-13, celvivo-app-note-2026, aiello-bagni-rc-cfd, tian-epicardium-mtor, kim-egain-3d-mea, ajongbolo-brain-organoid-review, tevonian-2026-vascularized-liver-mps, yang-2026-cardiac-organoid-review, shen-2026-vascularized-organoids-review, zhai-2026-3d-skin-pemphigus, vascularized-organoids, cardiac-organoids, skin-organoids]
+timestamp: 2026-08-25T18:13:00Z
 ---
 
 # Theme 5 · Robin's personal research (vendor deep reads + sales ammunition + CRM)
@@ -99,6 +99,9 @@ Snapshot from [`/sources/git-repo.md`](/sources/git-repo.md) (last fetch 2026-08
 | `Organoid-List/` | 51 | curated organoid reading lists |
 | `Product-Reports/` | 38 | vendor product reports |
 | `04-Literature/Deep-Reads/` root | +5 from 2026-08-23/24 single-shot LDR burst (CelVivo App Note + Aiello + Tian + Kim + Ajongbolo) — **non-standard pattern** vs prior per-vendor subfolder discipline |
+| `Vascularized-Organoids/` | 2 (NEW 2026-08-25 subfolder — Tevonian + Shen vascularized liver MPS / organoid review) | vascularized organoid (Tevonian primary + Shen review) |
+| `Cardiac-Organoids/` | 1 (NEW 2026-08-25 subfolder — Yang cardiac organoid review) | cardiac organoid |
+| `Skin-Organoids/` | 1 (NEW 2026-08-25 subfolder — Zhai 3D skin pemphigus) | autoimmune dermatology + 3D skin (net-new application domain) |
 | `Brain/` | 11 | brain organoid focus |
 | `Brain-Tumor/` | 9 | brain tumor organoid |
 | `Cancer/` | 6 | cancer organoid |
@@ -194,6 +197,8 @@ From [`/sources/literature.md`](/sources/literature.md) last sync, broken out by
 | Date | DOI / slug | Vendor | Topic |
 | --- | --- | --- | --- |
 | 2026-08-16 | **Quintard 2024 Nat Commun + Guo 2026 Front Cell Dev Biol 7-commit LDR cluster** (commits `0fc8db24` + `290e9635` + `24c713de` + `4073abf4` Quintard + `2e6f5989` + `00f824f2` + `a4fa5a32` Guo) | **CelVivo adjacent + Mimetas OrganoPlate ⭐⭐⭐⭐ + Emulate Organ-Chip ⭐⭐⭐** (Quintard) / **CelVivo ClinoStar ⭐⭐⭐⭐ + Mimetas OrganoPlate ⭐⭐⭐⭐ + Emulate Organ-Chip ⭐⭐⭐** (Guo) | Quintard C et al. (2024) A microfluidic platform integrating functional vascularized organoids-on-chip (Nat Commun DOI 10.1038/s41467-024-45710-4, Wiki ID 1719/1720/1722, NocoDB Id 3297; 10 通道并行微流控 + hiPSC-BVO 30 天功能性灌注培养 + 跨类器官验证 [间充质球体 / BVO / 胰岛球体 / 肺类器官]; 血管层级化 37 µm 上游动脉-静脉 + 8 µm BVO 毛细管, 壁剪切 27-2000 s⁻¹, 完美匹配人体毛细血管生理范围 50-1900 s⁻¹) + Guo Z & Zhang N (2026) Ethical review key considerations for organoid applications in biomedical research—a systematic review (Front Cell Dev Biol DOI 10.3389/fcell.2026.1721946, Wiki ID 1724, NocoDB Id 3298; 嘉兴市第一医院 + 嘉兴大学医学院视角; 类器官研究 IRB / 伦理审查 7 大强制要点系统综述 [样本来源/知情同意/数据隐私/共培养主体性/3R 动物福利/跨境监管/长期保存与终止使用] + 中国《人类遗传资源管理条例》+ 国际 ISSCR/GDPR/HIPAA 多国对照表). **Robin translated Guo 2026 into a customer-facing IRB application checklist template** (`templates/类器官IRB申请清单.md` v1.0 180 lines) — first customer-facing template produced from a single deep-read. |
+| 2026-08-25 | **SECOND consecutive single-day 5-paper LDR burst** (commits `089177a7` Tevonian + `583859a8` Yang + `9aa2af4c` vendor-mapping retrofit + `5907cdfc` Shen + `9d4767c7` Zhai) | **5-vendor product mapping retrofit on Tevonian + Yang** (CelVivo ClinoStar/ClinoReactor + Cellink BIO X + Mimetas OrganoPlate + 3Brain HD-MEA + FemtoBiomed CellShot) | **Tevonian 2026 Nat Commun vascularized liver MPS** (PMID 41634021, Wiki.js 1749; PDMS+fibrin+原代肝+HUVEC vascularized liver MPS, 14天 IR modeling, 单核细胞 infiltration enhancement; **first file in new Vascularized-Organoids/ subfolder**) + **Yang 2026 Stem Cell Res Ther cardiac organoid review** (PMID 41963991, Wiki.js 1750; 复旦 + InnoStar comprehensive review of hPSC cardiac organoid generation methods (FGF/PI3K/Wnt/BMP/Activin/RA 五大信号通路) + maturation protocols + disease modeling + regenerative medicine; **first file in new Cardiac-Organoids/ subfolder** — first new subfolder explicitly for an application-domain cluster) + **post-publish vendor-mapping retrofit commit `9aa2af4c`** on Tevonian + Yang (adds 5-vendor mapping table + 净化 Robin mentions; **first post-publish vendor-mapping retrofit step in Robin's LDR pipeline**, iterates the 8-step SOP to a 9-step SOP) + **Shen 2026 Chin Med J vascularized organoids review** (PMID 42268296, Wiki.js 1751; 华西医院 Chinese-language peer-reviewed systematic review of vascularized organoids 4 大策略 (共培养 + 转录因子诱导 + 微流控 + 生物材料支架) + 12 维对比 + 三大未来方向; second file in Vascularized-Organoids/ subfolder) + **Zhai 2026 Sci Adv 3D skin pemphigus** (PMID 41512055, Wiki.js 1752; 3D 打印 + 自组织 multilayer vascularized skin model for 天疱疮 autoimmune disease modeling + EGFR-targeted therapy + ML-assisted drug screening; **first file in new Skin-Organoids/ subfolder** — **net-new application domain** autoimmune dermatology + 3D skin). **3 NEW `04-Literature/Deep-Reads/` subfolders** created in a single day: `Vascularized-Organoids/` + `Cardiac-Organoids/` + `Skin-Organoids/` (Robin expands the deep-read folder taxonomy from ~19 → ~22, returning to per-vendor / per-application-domain subfolder discipline after the 2026-08-23/24 root-level non-standard pattern). **Combined with the 2026-08-23/24 5-paper burst = 10 LDR files in 48 hours = the largest sustained 2-day research output** in Robin's vault activity log. |
+| 2026-08-24 | **First 5-paper LDR burst in 24-hour window** (commits `ad4abcde` Ajongbolo + `5f02489a` Kim + `40b357b8` Tian + `f2118a62` Aiello + `fb017e4f` CelVivo App Note) | **CelVivo-aligned (3) + 3Brain-adjacent (1) + cardiac-epicardium (1)** | Ajongbolo 2025 Cells brain organoid review (PMID DOI 10.3390/cells14110842, Wiki.js 1743; canonical brain organoid + assembloid review with 3-tier taxonomy + 4-class characterization methodology) + Kim 2025 Nat Commun EGaIn liquid-metal 3D MEA (DOI 10.1038/s41467-024-55752-3, Wiki.js 1744; 25-310 µm pillar height, 14 µm diameter, magnetically reshapeable; 3Brain HD-MEA adjacent) + Tian 2025 Nat Commun hiPSC epicardium mTOR maturation (DOI 10.1038/s41467-025-60934-8, Wiki.js 1745; Torin1 dual mTORC1/2 inhibition drives mature epicardium via YBX3/MAFF TFs) + Aiello & Bagni 2025 biorxiv Rotating Chamber brain organoid CFD (Wiki.js 1746; COMSOL CFD < 20 mPa cavity shear stress, cross-organoid-line morphological CV < 15%) + CelVivo App Note 2026 shear stress ClinoStar vs orbital shaker (Wiki.js 1747; head-to-head comparison across HepG2/C3A + Caco-2 + brain organoid — first vendor App Note deep-read). **All 5 files landed at `04-Literature/Deep-Reads/` root** (non-standard pattern vs the prior per-vendor subfolder discipline). Vendor-anchor mapping: 3 CelVivo-aligned (CelVivo App Note + Aiello [ClinoStar-adjacent] + Ajongbolo mentions ClinoStar) + 1 3Brain-adjacent (Kim EGaIn 3D MEA — 3rd next-gen HD-MEA approach alongside Liu 2026 + 3Brain Accura-3D) + 1 cardiac epicardium (Tian mTOR, no vendor callouts). **Largest single-day LDR burst since the 2026-07-29 Parate / Lee / Hodge cluster**. |
 | 2026-08-12 | **Liang 2026 liver organoid fibrosis platform 4-commit LDR cycle** (commits `e542c977` + `8699a154` + `aacba7aa` + `297f106d`) | **CelVivo (ClinoStar rating 5 + ClinoReactor rating 5)** | Liang Y et al. (2026) A robust mouse liver organoid platform enables sustained multicellular maturation and fibrosis modeling from a single tissue sample (Sci Rep DOI 10.1038/s41598-026-42990-2, PMID 41857098; Wiki.js Id 1716, NocoDB Id 770; 3 轨道 Hep-Orgs + Cho-Orgs + HSC 同步分离; DAPT+Dex P1-P10 长程稳定成熟 [ALB/PAS/LDL/CYP 跨代保持]; TGFβ 激活 qHSC → aHSC [Acta2/Col1a1 上调]; aHSC 共培养诱导 Hep-Orgs EMT [Snail/Twist/Vimentin↑; ALB/CK8↓; Lgr5/EpCAM↓; Ki67↓] = 体外肝纤维化模型) — page 946 9 项 SOP 重写版 + page 934 修齐 标杆; 7/7 Ollama qwen2.5vl 视觉审核通过; SeaFile 7/7 公网 200 验真. First paper whose `related:` field already names `[[MOC-类器官与3D培养]]` (the 2026-08-10 first MOC) on the day of publication. |
 | 2026-08-10 | **Phase A metadata batch + first MOC** (commits `d97b39ed` + `6b717aef` + `3b929c2f`) | (process discipline) | 6 deep-reads received the 6-field frontmatter (doi/journal/year/volume/pages/authors/pmid); first MOC `MOC-类器官与3D培养.md` (95 lines, 沙牛《AI 时代的 Obsidian 公开课》课时 1 pattern) created at `04-Literature/Deep-Reads/MOCs/`; 7 image alt descriptions added on `wang2024-org-on-chip.md`. No new external evidence. |
 | 2026-08-09 | `10.7150/thno.90492` (Wang 2024) | (4 类共性硬件 — Organoid-on-Chip 综述) | Wang H et al. (2024) Human organoids-on-chips for biomedical research and applications (Theranostics 14(2):788-818, PMID 38169573; 7 图覆盖 7 大主题板块) — Wiki.js ID 1700 (v2 - grp:3 ghost page 累加) |