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chore: daily update 2026-08-11

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2026-08-11 02:11:51 +08:00
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@@ -22,7 +22,7 @@ This is the synthesis page for **Robin 个人研究项目** — the durable body
```mermaid
erDiagram
VAULT["Obsidian vault (d7df3830)"] ||--o{ DEEPREADS["Deep-read notes ~1,202"]
VAULT["Obsidian vault (d97b39ed)"] ||--o{ DEEPREADS["Deep-read notes ~1,202"]
VAULT ||--o{ TRAIN["Sales training (CelVivo赋能培训 v1-v9)"]
VAULT ||--o{ SALES["Active sales pipeline (惠百生物 PO + 中间商)"]
VAULT ||--o{ CRM["Distributor profiles (董慧群 + 待补)"]
@@ -30,6 +30,7 @@ erDiagram
VAULT ||--o{ INDUSTRIAL["Industrial customers (CelVivo中国工业客户开发)"]
VAULT ||--o{ MEMORY["Daily + weekly reports (memory/ 147 .md)"]
VAULT ||--o{ ITX["ITX 24h host build (untracked)"]
VAULT ||--o{ MOC["MOCs (类器官与3D培养 first, +planned)"]
DEEPREADS }o--|| VENDOR["Vendor mapping"]
VENDOR ||--|{ CelVivo["CelVivo (ClinoStar / ClinoReactor)"]
@@ -48,17 +49,18 @@ The diagram shows Robin's research substrate: a single Obsidian vault with 8 buc
## Knowledge substrate: Obsidian vault
Snapshot from [`/sources/git-repo.md`](/sources/git-repo.md) (last fetch 2026-08-08T18:11:31Z):
Snapshot from [`/sources/git-repo.md`](/sources/git-repo.md) (last fetch 2026-08-10T18:06:19Z):
| Field | Value |
| --- | --- |
| Repo path | `/home/ldw/workspace` |
| Branch | `main` |
| HEAD | `d7df3830a28a48b0129a46729ab2357e231a2ec5` (2026-08-08) |
| Ahead of origin/main | 9 commits new since 2026-08-03 fetch (Fernandez Vallone 2026 + Microbioreactor 2026 + Liu 2026 v2-v11 + 4 经销商 hook 升级); plus 19 untracked files in working tree |
| HEAD | `d97b39edb328b7e15d28de4a54a6d0bc2dd51274` (2026-08-10) |
| Ahead of origin/main | 12 commits new since 2026-08-03 fetch (Fernandez Vallone 2026 + Microbioreactor 2026 + Liu 2026 v2-v11 + 4 经销商 hook 升级 + Wang 2024 Theranostics + **Phase A metadata batch + 2 sample runs**); plus 19 untracked files in working tree |
| Auth | local path only — no remote, no credentials |
| Working-tree state | dirty (1 nested-submodule + 1 untracked dir + 19 untracked files including 8 new `02-Clients/Agents/区域-2026-0807.md`) |
| Raw manifest | `~/.openwiki/connectors/git-repo/raw/2026-08-08T18-11-31-856Z/manifest.json` |
| Raw manifest | `~/.openwiki/connectors/git-repo/raw/2026-08-10T18-06-18-966Z/manifest.json` |
| **Latest cluster (2026-08-10)** | **Phase A metadata batch** (`d97b39ed`) + **MOC 方案 1 样品** (`6b717aef`, first MOC `MOC-类器官与3D培养.md`) + **wang2024 方案 2 样品** (`3b929c2f`, 7 image alt descriptions) — frontmatter-hygiene + MOC-discipline sprint, no new external evidence |
### Vault navigation index (top-level folders)
@@ -174,12 +176,14 @@ From [`/sources/ldr-report-template.md`](/sources/ldr-report-template.md) (Robin
| Miao 2025 Cell v2 (2026-08-08 flywheel-sync) | CelVivo (ClinoStar rating 5) | `/home/ldw/workspace/Miao2025_Cell_v2.md` | [`/sources/literature-miao-2025-cell-vascularization-v2-deepread.md`](/sources/literature-miao-2025-cell-vascularization-v2-deepread.md) |
| Liu 2026 Nat Biomed Eng (2026-08-08 flywheel-sync) | 3Brain (HD-MEA rating 5) + Cellink (microlattice rating 5) | `/home/ldw/workspace/Liu2026_NBME_shape_conformal_organoid.md` | [`/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md`](/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md) |
## Recent 30-day research output (mtime 2026-06-16 → 2026-08-08)
## Recent 30-day research output (mtime 2026-06-16 → 2026-08-10)
From [`/sources/literature.md`](/sources/literature.md) last sync, broken out by vendor and date:
| Date | DOI / slug | Vendor | Topic |
| --- | --- | --- | --- |
| 2026-08-10 | **Phase A metadata batch + first MOC** (commits `d97b39ed` + `6b717aef` + `3b929c2f`) | (process discipline) | 6 deep-reads received the 6-field frontmatter (doi/journal/year/volume/pages/authors/pmid); first MOC `MOC-类器官与3D培养.md` (95 lines, 沙牛《AI 时代的 Obsidian 公开课》课时 1 pattern) created at `04-Literature/Deep-Reads/MOCs/`; 7 image alt descriptions added on `wang2024-org-on-chip.md`. No new external evidence. |
| 2026-08-09 | `10.7150/thno.90492` (Wang 2024) | (4 类共性硬件 — Organoid-on-Chip 综述) | Wang H et al. (2024) Human organoids-on-chips for biomedical research and applications (Theranostics 14(2):788-818, PMID 38169573; 7 图覆盖 7 大主题板块) — Wiki.js ID 1700 (v2 - grp:3 ghost page 累加) |
| 2026-08-08 | `10.3390/cells15110963` (Fernandez Vallone 2026) | (NAMs adjacent, hiPSC brain organoid) | THSDC chemical evaluation platform using hiPSC brain organoids (Cells, v2 5 张真图 + 双 H1; Wiki.js Id 1698) |
| 2026-08-08 | `10.3389/fbioe.2026.1854988` (Rosero 2026) | CelVivo + Cellink + FemtoBiomed adjacent | Microbioreactor design Mini Review (Front Bioeng Biotechnol; 6× productivity vs T-flask; 4 applications: CAR-T / mAb / iPSC / organoid) |
| 2026-08-08 | `10.1038/s41551-026-01620-y` (Liu 2026) | 3Brain (HD-MEA rating 5) + Cellink (microlattice rating 5) | Shape-conformal porous framework for full-coverage neural organoid e-phys — Rogers Lab, Nat Biomed Eng |
@@ -204,14 +208,15 @@ From [`/sources/literature.md`](/sources/literature.md) last sync, broken out by
By vendor (30-day mtime):
| Vendor | Most recent | 2026-08-08 additions |
| Vendor | Most recent | 2026-08-08 / 2026-08-10 additions |
| --- | --- | --- |
| CelVivo | 2026-08-08 (Miao 2025 v2 — ClinoStar rating 5) | +Miao 2025 v2 (ClinoStar co-differentiation), +Sharma 2026 (ClinoStar rating 3 adjacent), +Liu 2026 (ClinoStar rating 4 adjacent) |
| 3Brain | 2026-08-08 (Liu 2026 — HD-MEA rating 5) | +Liu 2026 (shape-conformal framework, next-gen HD-MEA), +Sharma 2026 (HD-MEA rating 4 adjacent) |
| 3Brain | 2026-08-08 (Liu 2026 — HD-MEA rating 5) | +Liu 2026 (shape-conformal framework, next-gen HD-MEA), +Sharma 2026 (HD-MEA rating 4 adjacent), +Shin 2024 (Phase A frontmatter hygiene on existing note) |
| Cellink | 2026-07-27 (Tasevska 2025) | +Liu 2026 (microlattice fabrication rating 5 adjacent) |
| Adjacent (no vendor) | 2026-08-08 (Sharma 2026 retinal vascularization) | +Sharma 2026 (retinal organoid application domain) |
| (Process discipline) | 2026-08-10 (Phase A batch + first MOC) | +6 deep-reads received 6-field frontmatter; +first MOC `MOC-类器官与3D培养.md` created; +7 image alt descriptions on Wang 2024 — no new external evidence |
The pipeline is **vendor-balanced** — CelVivo, 3Brain, Cellink each have a recent deep read, and today's flywheel-sync (2026-08-08) adds **3 papers spanning all 3 primary vendors + the retinal organoid application domain** (Sharma), all 3 rated 4-5 on at least one vendor's product line. The **first entry in the new NocoDB table `Robin_Picked_Papers`** is Liu 2026 (created 2026-08-08 per Robin instruction to capture papers Robin hand-picks / provides outside the regular PubMed triage).
The pipeline is **vendor-balanced** — CelVivo, 3Brain, Cellink each have a recent deep read, and the 2026-08-08 flywheel-sync adds **3 papers spanning all 3 primary vendors + the retinal organoid application domain** (Sharma), all 3 rated 4-5 on at least one vendor's product line. The 2026-08-10 cluster is **process discipline** (Phase A metadata batch + first MOC creation + Wang 2024 alt-description sample), not new external evidence — the 6 deep-reads already existed on `main`; the 3 commits only normalize their metadata and add a knowledge-graph index layer. The **first entry in the new NocoDB table `Robin_Picked_Papers`** is Liu 2026 (created 2026-08-08 per Robin instruction to capture papers Robin hand-picks / provides outside the regular PubMed triage). The **first MOC** `MOC-类器官与3D培养.md` is the start of a Map-of-Content layer Robin appears to be building (the MOC's own `related:` already names `[[MOC-3Brain-HD-MEA]]` as the next planned MOC).
## Sales ammunition pipeline
@@ -347,6 +352,25 @@ These are source-anchored but not vendor-anchored — they live here for traceab
- **Work-rhythm snapshot connector** — currently a one-shot `find -mtime` shell command (see `/sources/vault-mtime-snapshot-2026-07-16.md` header). Promote to a weekly cron + auto-write to `/sources/vault-mtime-snapshot-weekly.md` so the work-rhythm signal is durable, not single-snapshot.
- **End-customer dossier cross-agent page** — 11+ dossiers live in private vault; consider adding a redacted `[name, focus, vendor, region, vault-path]` table to `/sources/agents.md` parallel to the distributor profile pattern. Robin decision pending.
- **CellShot-TriArm demo plan v3** — current demo plans are v1 (2026-07-21) and v2 (2026-07-22, 邮件用 + 老师版 two-commit split). No v3 yet; the v2 plan lives in vault commit history `1787702c` / `62877d1f` / `62d09c5f`. Promote to `/commitments.md` when v3 lands.
- **MOC pattern extension (2026-08-10 onward)** — Robin created the first MOC
(`04-Literature/Deep-Reads/MOCs/MOC-类器官与3D培养.md`, commit `6b717aef`,
95 lines, 沙牛《AI 时代的 Obsidian 公开课》课时 1 pattern); the MOC's
`related:` list already names the next planned MOC —
`[[MOC-3Brain-HD-MEA]]` — plus
`[[02-Clients/Agents/_known_associations]]` and
`[[02-Active-Deals/CellShot-TriArm-Demo-计划-v2-老师版-2026-07-20]]`.
Track on the next git-repo fetch whether the MOC pattern extends to
MOC-3Brain-HD-MEA, MOC-Cellink-BIO-X, MOC-Femtobiomed-CellShot, etc.
If ≥3 MOCs land, consider adding a `/themes.md` annex row on
`vault-knowledge-architecture` and a `/sources/` page that maps the
MOC graph (file → topics → cross-refs → flywheel cron hooks).
- **Phase A frontmatter batch rollout (2026-08-10 onward)** — Phase A
standardized 6 deep-read notes with the 6-field frontmatter
(doi / journal / year / volume / pages / authors / pmid); ~1,196
deep-read notes remain without the new fields. Track rollout
cadence — if Robin completes the batch on a fixed cadence (e.g.
daily/weekly cron), document the cadence here so future agents can
answer "what is the frontmatter hygiene status of the vault?".
## What to read next