chore: daily update 2026-07-29

This commit is contained in:
OpenWiki Bot
2026-07-29 02:12:55 +08:00
parent fa3c82079f
commit 61cd78a06a
8 changed files with 184 additions and 42 deletions
+68 -30
View File
@@ -11,19 +11,24 @@ the vault, not summarize their content.
- **Instance:** `obsidian-robin` (source id `obsidian-robin-1`)
- **Repo path:** `/mnt/c/Users/20864/.openclaw/workspace`
- **Branch:** `main`
- **HEAD:** `62877d1f3940c85fbc95c090aec4c03ee76c04cc` (2026-07-22)
- **Ahead of origin/main:** 3 commits (the `CellShot-TriArm-Demo` plan v1 + v2
pair, un-pushed as of this run).
- **HEAD:** `21491578ec22733f15efda864e88e44823171e6a` (2026-07-28)
- **Ahead of origin/main:** 7 commits (3 CellShot-TriArm-Demo plans + 4 new commits
dated 2026-07-28: Hodge 2025 / Lee 2025 / Parate 2020 deep reads + 董慧群
CelVivo distributor technical-contact profile, un-pushed as of this run).
- **Auth:** local path only — no remote, no credentials
- **Latest fetch:** `2026-07-27T18:07:54Z` (no commit delta vs. 2026-07-26T18:16:06Z prior pull; 4 new untracked files dated 2026-07-27)
- **Raw manifest:** `~/.openwiki/connectors/git-repo/raw/2026-07-27T18-07-54-571Z/manifest.json`
- **Latest fetch:** `2026-07-28T18:07:57Z` (HEAD advanced from `62877d1f``21491578`,
+4 commits; untracked working-tree list unchanged from the prior pull)
- **Raw manifest:** `~/.openwiki/connectors/git-repo/raw/2026-07-28T18-07-57-114Z/manifest.json`
- **Source config:** `~/.openwiki/connectors/git-repo/config.json`
## Working-tree status
- **Dirty:** yes
- **Modified:** `skills/openclaw-workspace``git diff --stat` reports 0
insertions / 0 deletions (touch-only mtime change; no content delta).
- **Modified:** `skills/openclaw-workspace`submodule now reports
`4e81a914b5f4ed52d88e0b31476354f92fcd4be7-dirty` (was
`4e81a914b5f4ed52d88e0b31476354f92fcd4be7` on the prior pull). The only diff is
the `-dirty` suffix marker; the recorded commit hash is unchanged. No content
delta.
- **Untracked (5 files):**
- `04-Literature/Deep-Reads/3Brain/3Brain_Sample_Holder_Set_PressNet_2026-07-07.md`
— 3Brain UK GB2624872 Sample Holder Set / CorePlate 压网装置 note
@@ -31,27 +36,30 @@ the vault, not summarize their content.
- `04-Literature/Deep-Reads/3Brain/Raji_2026_hMOs_dopaminergic_3Brain_MEA_2026-07-27.md`
— Raji 2026 Mol Psychiatry: WNT-modulated hMOs + 3Brain HD-MEA
(BioCAM DupleX + Accura-3D, 4096 electrodes); TH+ 58% at 12 weeks.
Date stamp 2026-07-27. *(NEW this pull)*
Date stamp 2026-07-27. *(carryover from prior pull)*
- `04-Literature/Deep-Reads/Cellink/Tasevska_2025_HCTZ_3D_printed_extended_release_2026-07-27.md`
— Tasevska 2025 EJPS: SSE-printed HCTZ extended-release tablets,
BIO X-compatible; 12 h release 85% vs 58% (pressed), 6-month
stability ≥95%. Date stamp 2026-07-27. *(NEW this pull)*
stability ≥95%. Date stamp 2026-07-27. *(carryover from prior pull)*
- `04-Literature/Deep-Reads/Celvivo/Bosnjakovic_2025_PAH_3D_spheroid_CelVivo_ClinoStar_2026-07-27.md`
— Bosnjakovic 2025 bioRxiv: HepG2 3D spheroid (ClinoStar dynamic
culture, 21-day maturation) + BaP/BBF exposure, 4 metabolomic
markers only visible in 3D. Date stamp 2026-07-27. *(NEW this pull)*
markers only visible in 3D. Date stamp 2026-07-27. *(carryover from prior pull)*
- `OpenWiki速查手册_2026-07-27.md` (vault root) — Robin's OpenWiki
cheat sheet ("一天 6 次对话的完整沉淀"). Date stamp 2026-07-27.
*(NEW this pull)*
*(carryover from prior pull)*
Since the prior fetch (2026-07-26T18:16:06Z), zero new commits have landed on
`main` — HEAD is unchanged at `62877d1f` (2026-07-22, 5 days old, still
inside the 7-day "vault fresh" window). Working-tree deltas this run: the
same touch-only `skills/openclaw-workspace` mtime plus the four 2026-07-27
untracked files listed above. The earlier
`3Brain_Sample_Holder_Set_PressNet_2026-07-07.md` note remains untracked
from the prior pull. Companion deep-read pages already exist for the three
new vendor-paper notes: `/sources/literature-raji-2026-deepread.md`,
Since the prior fetch (2026-07-27T18:07:54Z), **4 new commits have landed on
`main`** — HEAD advanced from `62877d1f` (2026-07-22) to `21491578`
(2026-07-28). All four are dated 2026-07-28 and are well inside the 7-day
"vault fresh" window, so the staleness rule does not fire. Working-tree
deltas this run: the `skills/openclaw-workspace` submodule `-dirty` suffix
(unchanged commit hash; no content delta) plus the same 5 untracked files
the prior pull already recorded. The three new 2026-07-28 vendor-paper
deep reads landed as **committed** files this pull, not as untracked working
files — they appear in the Recent commits table below, not above.
Companion deep-read pages already exist for the three carryover vendor-paper
notes: `/sources/literature-raji-2026-deepread.md`,
`/sources/literature-tasevska-2025-deepread.md`, and
`/sources/literature-cel-bosnjakovic-2025-pah-deepread.md`.
@@ -96,17 +104,23 @@ Markdown file counts per deep-read subfolder:
| `Brain-Tumor/` | 9 |
| `Cancer/` | 6 |
| `Liver/` | 6 |
| `Other/` | 4 |
| `Other/` | 6 |
| `RegenMed/` | 1 |
| `3Brain MEA/` | 3 |
| `Cardiac/` | 2 |
| `Kidney/` | 2 |
| `Retinal/` | 1 |
Total ≈ 1,199 deep-read notes (+4 untracked vendor-paper deep-reads
dated 2026-07-27: +1 CelVivo, +1 3Brain, +1 Cellink; the Organoid/ bucket is
unchanged since none of the new files land there). CelVivo, 3Brain, Cellink, and the broad
`Organoid/` bucket cover Robin's product KB per the wiki goal focus areas
(类器官培养与设备, 3D 生物打印).
Total ≈ 1,201 deep-read notes (+3 committed 2026-07-28 vendor/adjacent
deep-reads since the prior pull: +2 `Other/` — Lee 2025 Front Vet Sci
canine MSC 3D spheroid + Parate 2020 SCRT PEMF MSC paracrine cartilage;
+1 new `RegenMed/` bucket — Hodge 2025 Bio-Block MSC 4-week comparison;
the Organoid/ bucket is unchanged since none of the new files land there).
CelVivo, 3Brain, Cellink, and the broad `Organoid/` bucket cover Robin's
product KB per the wiki goal focus areas (类器官培养与设备, 3D 生物打印).
The new `RegenMed/` bucket is application-domain adjacent (Bio-Block vs.
spheroid vs. Matrigel MSC long-term culture) and is the kind of vendor-
adjacent signal the existing `class-organoid-3d-bioprinting` row folds in.
## Recent commits (latest first)
@@ -115,6 +129,10 @@ Pulled from the manifest's `recentCommits` field. Date stamps via
| Date | Hash | Note |
| --- | --- | --- |
| 2026-07-28 | 21491578 | feat(agent): 新增代理商技术同事董慧群档案 (推 CelVivo 产品) |
| 2026-07-28 | 652e0e60 | feat(literature): Parate 2020 SCRT — PEMF 增强 MSC 旁分泌功能促软骨再生 (中文精读, 10 图 + 4 功能) |
| 2026-07-28 | ee34cf83 | feat: 精读 Lee 2025 Front Vet Sci 犬脂肪源 MSC 3D 球体(Wiki.js Id=1645, NocoDB Id=3290 |
| 2026-07-28 | 5ddda558 | feat(literature): Hodge 2025 RegenMed — Bio-Block 4周 MSC 长期培养对比 + Wiki.js + SeaFile 7图 PDF 完整精读 |
| 2026-07-22 | 62877d1f | feat(demo-plan): CellShot-TriArm Demo 计划 v2 纯文本版 (2026-07-20) — 邮件用 |
| 2026-07-22 | 62d09c5f | feat(demo-plan): CellShot-TriArm Demo 计划 v2 老师版 (2026-07-20) |
| 2026-07-21 | 1787702c | feat(demo-plan): CellShot-TriArm Demo 计划 v1 (2026-07-20) |
@@ -153,12 +171,23 @@ commits (the recent `工业客户开发手册`, `Robin稿生成通字稿`, `销
| Path | Change | Note |
| --- | --- | --- |
| `skills/openclaw-workspace` | modified | touch-only, no content delta (unchanged from prior pull) |
| `skills/openclaw-workspace` | modified | submodule suffix `-dirty` (recorded hash unchanged; no content delta) |
| `04-Literature/Deep-Reads/3Brain/3Brain_Sample_Holder_Set_PressNet_2026-07-07.md` | untracked (carryover) | 3Brain UK GB2624872 Sample Holder Set / CorePlate 压网装置 note |
| `04-Literature/Deep-Reads/3Brain/Raji_2026_hMOs_dopaminergic_3Brain_MEA_2026-07-27.md` | untracked (NEW) | Raji 2026 Mol Psychiatry — WNT-modulated hMOs + 3Brain HD-MEA (Accura-3D 4096 electrodes) |
| `04-Literature/Deep-Reads/Cellink/Tasevska_2025_HCTZ_3D_printed_extended_release_2026-07-27.md` | untracked (NEW) | Tasevska 2025 EJPS — SSE-printed HCTZ extended-release tablets, BIO X-compatible |
| `04-Literature/Deep-Reads/Celvivo/Bosnjakovic_2025_PAH_3D_spheroid_CelVivo_ClinoStar_2026-07-27.md` | untracked (NEW) | Bosnjakovic 2025 bioRxiv — HepG2 3D spheroid (ClinoStar dynamic culture) + PAH exposure |
| `OpenWiki速查手册_2026-07-27.md` | untracked (NEW) | Robin's OpenWiki cheat sheet (vault root) |
| `04-Literature/Deep-Reads/3Brain/Raji_2026_hMOs_dopaminergic_3Brain_MEA_2026-07-27.md` | untracked (carryover) | Raji 2026 Mol Psychiatry — WNT-modulated hMOs + 3Brain HD-MEA (Accura-3D 4096 electrodes) |
| `04-Literature/Deep-Reads/Cellink/Tasevska_2025_HCTZ_3D_printed_extended_release_2026-07-27.md` | untracked (carryover) | Tasevska 2025 EJPS — SSE-printed HCTZ extended-release tablets, BIO X-compatible |
| `04-Literature/Deep-Reads/Celvivo/Bosnjakovic_2025_PAH_3D_spheroid_CelVivo_ClinoStar_2026-07-27.md` | untracked (carryover) | Bosnjakovic 2025 bioRxiv — HepG2 3D spheroid (ClinoStar dynamic culture) + PAH exposure |
| `OpenWiki速查手册_2026-07-27.md` | untracked (carryover) | Robin's OpenWiki cheat sheet (vault root) |
In addition, the 4 commits added on 2026-07-28 brought these files into
`main` (visible in `git log` and the manifest's `recentCommits` field, not
in the `git status` dirty tree):
| Path | Change | Note |
| --- | --- | --- |
| `02-Clients/Agents/董慧群.md` | added (commit `21491578`) | new CelVivo distributor technical-contact profile (mostly 待补) |
| `04-Literature/Deep-Reads/Other/2026-07-28_Parate_2020_SCRT_PEMF_MSC_paracrine_cartilage.md` | added (commit `652e0e60`) | Parate 2020 Stem Cell Res Ther — PEMF增强MSC旁分泌功能促软骨再生 |
| `04-Literature/Deep-Reads/Other/2026-07-28_Lee_2025_FrontVetSci_canine_MSC_3D_spheroid.md` | added (commit `ee34cf83`) | Lee 2025 Front Vet Sci — 犬脂肪源MSC 3D球体 (Wiki.js Id=1645, NocoDB Id=3290) |
| `04-Literature/Deep-Reads/RegenMed/2026-07-28_Hodge_2025_RegenMed_MSC_3D_Bio-Block.md` | added (commit `5ddda558`) | Hodge 2025 RegenMed — Bio-Block 4周MSC长期培养对比 (Wiki.js + SeaFile 7图 PDF) |
## Notable entities surfaced by the vault (structural hints only)
@@ -174,6 +203,15 @@ commits (the recent `工业客户开发手册`, `Robin稿生成通字稿`, `销
`03-Resources/End-Customers/` covering 神经所 (上海), 北京大学, 北京天坛医院,
浙大一附院, 中科院昆明动物所, 西南医科大学, 贵州医科大学, plus TCM accounts
at 云南中医药大学 and 天津创新中药.
- **CelVivo distributor technical contact (new 2026-07-28)** — `02-Clients/Agents/董慧群.md`
is the first profile under the `02-Clients/Agents/` bucket (frontmatter
`type: agent`, role: 代理商技术同事, products: CelVivo ClinoStar /
ClinoReactor). Robin was told about 董慧群 via WeChat DM on 2026-07-28 —
role is to help push CelVivo products at the technical / demo / selection
stage. The profile is mostly 待补 (agency name, region, phone, WeChat,
customers, opportunities are all empty placeholders). Logged as an open
question on `/open-questions.md` because the agent can not reason about
CelVivo-channel activity without these fields.
- **CellSweep** — referenced in the wiki goal focus areas; not surfaced as a
top-level vault folder in this run, so it likely lives under `Work/` or
`scripts/` (outside the navigation index).
+44 -3
View File
@@ -8,10 +8,51 @@ Compact evidence trail for the Hacker News connector (`hackernews-1`, Robin-cura
- **Backend:** public HN feeds (`top`, `new`) + Algolia HN search queries
- **Auth:** none — public feeds
- **Window:** last 24 hours
- **Latest fetch:** `2026-07-27T18:00:47Z` (latest 18:00 pull on 2026-07-27; prior 2026-07-26 18:16 and 18:00 pulls also documented below)
- **Raw dumps:** `~/.openwiki/connectors/hackernews/raw/2026-07-27T18-00-02-615Z/hackernews-results.json` (current) · `~/.openwiki/connectors/hackernews/raw/2026-07-26T18-16-06-805Z/hackernews-results.json` · `~/.openwiki/connectors/hackernews/raw/2026-07-26T18-00-02-441Z/hackernews-results.json`
- **Latest fetch:** `2026-07-28T18:00:42Z` (latest 18:00 pull on 2026-07-28; prior 2026-07-27 18:00, 2026-07-26 18:16 and 18:00 pulls also documented below)
- **Raw dumps:** `~/.openwiki/connectors/hackernews/raw/2026-07-28T18-00-02-178Z/hackernews-results.json` (current) · `~/.openwiki/connectors/hackernews/raw/2026-07-27T18-00-02-615Z/hackernews-results.json` · `~/.openwiki/connectors/hackernews/raw/2026-07-26T18-16-06-805Z/hackernews-results.json` · `~/.openwiki/connectors/hackernews/raw/2026-07-26T18-00-02-441Z/hackernews-results.json`
## Latest update — 2026-07-27 18:00 UTC
## Latest update — 2026-07-28 18:00 UTC
- **Coverage:** 2 feeds (`top`, `new`), 24 search queries (the same life-science + workflow set the 2026-07-27 18:00 pull used), 58 unique resolved feed stories, and the life-science / vendor / workflow lane hit table below.
- **Life-science lane:** `organoid` returned 6 hits — one genuinely relevant (`49083799`, owlposting drug-discovery essay, 9 pts — see `class-organoid-3d-bioprinting (refreshed this run)` below); the rest were string collisions (Countify no-code computer vision, Shoebox Plus, "Bonfire" communities, anti-fraud, plus the YC S26 Rise Reforming launch also caught by the `Cellink` query). `3Brain` returned 8 hits (all string collisions: aeon bioenergetics essay, SpiNNaker2 chip, "local-first second brain" repo, "Use Your Brain" engineering blog, "Rachel has a new brain" reddit post, "Brain waves as noise" essay). `Cellink` returned 3 hits (Nutaan voice assistant, Rise Reforming — same as `organoid`, and a Kimi-K3 downloader). `liver organoid` and `brain organoid` each returned 1 hit — both string collisions (Shoebox Plus, Countify). `CELVIVO`, `3D bioprinting`, `3D bioprinter`, `bioprinting clinical`, `spheroid bioreactor`, `microgravity cell culture`, `MEA neuroscience`, `organ-on-chip`, `spheroid drug screening` all returned `nbHits=0` — the prior pulls' "no material HN footprint for the 4 vendor lines" finding still holds.
- **Workflow lane:** `OpenWiki`, `OpenWiki personal brain`, `RAGFlow`, `agent memory wiki`, `agent personal brain` all returned `nbHits=0`. `Hermes Agent` returned 2 hits (NoClick always-on agent Show HN 3 pts; Ami local busywork agent Show HN 8 pts) — both generic local-agent products, none on Robin's named stack. `Codex CLI` returned 28 hits (recurring wrapper / harness / "letting agents loose in VMs" cluster — already covered in prior pulls; nothing about Hermes / MiniMax / OpenWiki / RAGFlow). `Claude Code agent workflow` returned 2 hits (Tines 3B 22 pts; Dn "plan collaboratively, let agents execute" 3 pts) — both generic workflow Show HNs, off-scope. `MCP connector agent` returned 3 hits (Cynative read-only CLI 5 pts; Flashpaper secret sharing 14 pts; DynoTable DynamoDB GUI 1 pt) — none touch Robin's MCP config or named tools. `MiniMax` returned 6 hits including `49076505` (127 pts, "Kimi K3 Now Available via Telnyx Inference API") — Kimi/K3 cluster, MiniMax string collision only.
- **High-engagement top-feed items not promoted:** `49080664` 7.1 Earthquake in Japan (712 pts); `49083314` "New HIV vaccine shows unprecedented success in preclinical study" (368 pts) — life sciences but outside Robin's 4 application domains (3D cell culture / 3D bioprinting / neuroscience in vitro / organoid workflows), so off-scope per brief; `49082022` Kimi Linear attention architecture (209 pts); `49085909` Kimi Delta Attention explainer (158 pts); `49085698` Kimi K3 Architecture Overview (78 pts); `49076505` Kimi K3 via Telnyx (127 pts via MiniMax query); `49084987` "Now Is the Time to Give LLMs Access to the ACM Digital Library" (35 pts); `49086987` "Scientific computing in the age of agentic AI" (12 pts).
- **Synthesis result:** refreshed `class-organoid-3d-bioprinting` Last seen on `/themes.md` to 2026-07-28 (item `49083799`, 9 pts, drug-discovery / organoid essay). No new row added. No commitment row, no open-question row. The Kimi/K3 cluster continues to dominate the workflow lane at high engagement but stays off-scope per the brief (open-weight AI never earns a themes.md row).
| Query lane | Queries run | Qualifying results |
| --- | --- | --- |
| Life sciences / vendors | `organoid`, `3D bioprinting`, `3D bioprinter`, `bioprinting clinical`, `spheroid bioreactor`, `microgravity cell culture`, `CELVIVO`, `3Brain`, `Cellink`, `MEA neuroscience`, `organ-on-chip`, `liver organoid`, `brain organoid`, `spheroid drug screening` | 1 (`49083799` — owlposting "Why haven't organoids solved all of drug discovery?") |
| AI workflow | `OpenWiki`, `OpenWiki personal brain`, `Hermes Agent`, `Claude Code agent workflow`, `Codex CLI`, `RAGFlow`, `agent memory wiki`, `agent personal brain`, `MCP connector agent`, `MiniMax` | 0 new/promotable |
### class-organoid-3d-bioprinting (refreshed this run)
- **49083799** — score 9 — search hit (`organoid`) — "Why haven't organoids solved all of drug discovery?" (owlposting.com). https://www.owlposting.com/p/why-havent-organoids-solved-all-of. Drug-discovery / organoid essay on adoption gaps in preclinical organoid workflows; fits the `class-organoid-3d-bioprinting` theme's organoid + drug-screening application-domain coverage. Engagement is low (9 pts) so it does **not** qualify for the "manual review candidate" rule (needs ≥ 200 pts), but it does refresh the Last seen on `/themes.md` so the theme does not go stale like the 2026-07-26 run almost let it.
### Adjacent items not promoted
These are off-scope per the brief but worth flagging on this page for traceability; none earn a `/themes.md` row:
- **49080664** — score 712 — top — "7.1 Earthquake in Japan". News headline, not life-sciences / workflow.
- **49083314** — score 368 — top — "New HIV vaccine shows unprecedented success in preclinical study" (Nature, modeling in macaques). High-engagement life-sciences news but outside Robin's named 4 application domains — out of scope per brief.
- **49082022** — score 209 — top — "Kimi Linear: An Expressive, Efficient Attention Architecture" (Moonshot AI). Kimi/K3 cluster; off-scope per brief (open-weight AI never earns a themes.md row).
- **49085909** — score 158 — top — "You Could Have Come Up with Kimi Delta Attention" (doubleword.ai). Kimi/K3 cluster; off-scope.
- **49076505** — score 127 — new — "Kimi K3 Now Available via Telnyx Inference API". Returned by the `MiniMax` query — name collision with Moonshot Kimi; not Robin's MiniMax-M3 model provider. Off-scope.
- **49085698** — score 78 — top — "Kimi K3 Architecture Overview and Notes". Kimi/K3 cluster; off-scope.
- **49084371** — score 22 — Codex CLI / Claude Code agent workflow — Show HN: Tines 3B ("safe workflow automation for when everyone builds software"). Generic workflow tool, off-scope.
- **49085503** — score 14 — top — Show HN: Flashpaper (self-destructing secret sharing). Returned by `MCP connector agent` query. Off-scope.
- **49086987** — score 12 — top — "Scientific computing in the age of agentic AI". Adjacent to Robin's stack (agent tooling theme) but not a direct change to a named tool. Off-scope.
- **49076625** — score 8 — Hermes Agent — Show HN: Ami ("A local, open-source agent that does your busywork across apps"). Generic local-agent product, off-scope.
- **49084323** — score 2 — Codex CLI — Show HN: Cetus ("A macOS App for Claude Code, Codex, OpenCode, and More"). Mac-app wrapper; off-scope.
- **49087432** — score 1 — 3Brain — "The SpiNNaker2 chip: a many-core platform for brain-inspired computing" (arxiv). Brain-inspired computing chip ≠ MEA / Robin's 3Brain MEA chip line. Off-scope.
- **49087585** — score 1 — 3Brain — "Understanding bioenergetics can help our brain health" (aeon.co). Neuroscience essay; off-scope.
- **49086639** — score 3 — Hermes Agent / Codex CLI — Show HN: NoClick ("Build always-on agents with your existing AI subscriptions"). Generic always-on-agent product; off-scope.
- **49083082** — score 3 — Claude Code agent workflow — Show HN: Dn ("plan collaboratively, let agents execute"). Off-scope.
- **49086558** — score 5 — Codex CLI / MCP connector agent — Show HN: Cynative ("Read-only CLI in Go that explains your live infrastructure"). Off-scope.
- **49082126** — score 1 — MCP connector agent — Show HN: DynoTable ("The DynamoDB GUI with real SQL and your AI agent"). Off-scope.
Raw dump: `~/.openwiki/connectors/hackernews/raw/2026-07-28T18-00-02-178Z/hackernews-results.json`.
## Update — 2026-07-27 18:00 UTC
- **Coverage:** 2 feeds (`top`, `new`), 24 search queries, 51 unique resolved feed stories, and the life-science / vendor / workflow lane hit table below.
- **Query-set note:** this run reverted to the broader 24-query set the 2026-07-26 18:00 pull used (life-science **plus** OpenWiki/Hermes/MiniMax/Codex CLI/RAGFlow/MCP). The 18:16 vendor-only trim from the prior pull was reverted, so both lanes are back in coverage — consistent with the brief's "keep both lanes" rule.
+52 -1
View File
@@ -172,5 +172,56 @@ All three items fold into the existing `class-organoid-3d-bioprinting` row. Last
- Pull 2: fetched 2026-07-26T18:07:27Z — raw `~/.openwiki/connectors/web-search/raw/2026-07-26T18-07-14-335Z/web-search-results.json`
- Pull 3: fetched 2026-07-26T18:16:21Z — raw `~/.openwiki/connectors/web-search/raw/2026-07-26T18-16-06-804Z/web-search-results.json`
- Pull 4: fetched 2026-07-27T18:04:46Z — raw `~/.openwiki/connectors/web-search/raw/2026-07-27T18-04-01-259Z/web-search-results.json`
- Queries: pulls 1, 2, 4 = 10 queries each; pull 3 = 6 queries (vendor-anchored only)
- Pull 5: fetched 2026-07-28T18:04:26Z — raw `~/.openwiki/connectors/web-search/raw/2026-07-28T18-03-43-560Z/web-search-results.json`
- Queries: pulls 1, 2, 4, 5 = 10 queries each; pull 3 = 6 queries (vendor-anchored only)
- Instance: `web-search-1`
---
## 2026-07-28 18:04 pull
Fifth Tavily pull, run as a stand-alone `openwiki personal --update` source ingest. All 10 queries re-run. Two lanes produced genuinely new material evidence (China Order No. 818 regulatory shift; LLM Wiki + OKF shared-memory architecture cluster). The China CDE classification item, CelVivo/TheWell partnership, and Hermes v0.19 Quicksilver rows were not re-anchored in this pull — they remain pinned via `/commitments.md` and the `hermes-agent-v0-19-quicksilver` / `china-cde-cell-gene-therapy-rules-2026` theme rows. Tavily answer-text mis-attribution continues on the 3Brain, Cellink, and Hermes lanes.
### China Order No. 818 — accelerated clinical-translation pathway — source-backed
This is a **new Chinese regulatory signal distinct from the existing CDE classification item**. Order No. 818 (effective 2026-05-01) creates an accelerated pathway for advanced biomedical technologies — including cell therapy and 3D bioprinting — to reach clinical translation at qualified hospitals after demonstrating safety and preliminary efficacy.
- **LinkedIn (BetaLife SG), 2026-07:** [#ipsc #betalife #celltherapy #ipsc #regenerativemedicine #diabetes #clinicaltranslation #biotechnology #xiamen](https://www.linkedin.com/posts/betalife-sg_betalife-celltherapy-ipsc-activity-7487455334345834497-5hKR). Score 0.779. Explicitly references "Order No. 818, effective May 1, 2026. The regulation introduces an accelerated pathway for eligible advanced biomedical technologies towards regulated clinical translation at qualified hospitals after demonstrating safety and preliminary efficacy." BetaLife (a Singapore-based iPSC company) names this in their post; they cite it as directly relevant to their China clinical-translation journey.
- **Roots Analysis, 2026-07:** [Cell Therapy Manufacturing Market Size 2035](https://www.rootsanalysis.com/reports/cell-therapy-manufacturing/285.html). Score 0.669. Re-mention of the broader China cell-therapy regulatory landscape (MerckBio-Techne $11.3B acquisition, CARsgen China approval). Not an Order No. 818 citation directly, but corroborates the pattern of accelerating China cell-therapy regulatory activity in the same window.
- **Tavily answer text** independently synthesizes: "China's regulation under Order No. 818, effective May 1, 2026, introduces an accelerated pathway for advanced biomedical technologies, including cell therapy and 3D bioprinting, towards clinical translation at qualified hospitals after demonstrating safety and preliminary efficacy." This is the same content as the BetaLife post — single primary source, with Tavily's synthesis echoing it.
**Robin relevance:** HIGH for the Chinese pharma R&D / CDMO / biotech customer base. Order No. 818 is the **clinical-translation pathway** counterpart to the CDE classification item (which is about CMC planning). Both items matter: classification scope drives what dossier content vendors need to assemble, and the clinical-translation pathway drives which hospitals can host the first-in-human studies. Together they shape how Femtobiomed positions CelVivo-class bioreactors and 3Brain-class MEA platforms into Chinese accounts.
**Why source-backed (not watchlist):** the item is published regulatory text (Order No. 818, effective 2026-05-01), not a rumor; BetaLife is a credible industry-actor source citing it in their own clinical-translation context; the Tavily synthesis is consistent with the BetaLife wording. Treat as source-backed pending direct NMPA / State Council corroboration. **Promoted** to `/themes.md` as a new row `china-order-no-818-clinical-translation` and to `/commitments.md` as a verification item.
### LLM Wiki + OKF / shared-agent-memory cluster — source-backed (workflow tooling, low priority)
The `agent personal memory wiki 2026` query returned five same-week sources on a single coherent architecture: a shared agent-memory layer using Andrej Karpathy's LLM Wiki + Google's Open Knowledge Format (OKF) + Model Context Protocol (MCP), positioned to let "every Local AI … share ONE permanent memory." This is directly adjacent to OpenWiki's role.
- **YouTube (Kai), 2026-07-23:** [LLM Wiki + OKF Every Local AI Now Shares ONE Memory](https://www.youtube.com/watch?v=9ciGYHHOLyU). Score 0.752. Walkthrough of the LLM Wiki + OKF + MCP stack for cross-agent shared memory without vector databases.
- **Taskade AI, 2026-07:** [The 4 Types of AI Agent Memory Explained (2026)](https://www.taskade.com/wiki/ai-agents/memory-types). Score 0.705. Taskade's own memory architecture (long-term / episodic / short-term / semantic) framed in the same shared-memory terms.
- **GitHub (SamurAIGPT), 2026-07:** [SamurAIGPT/llm-wiki-agent](https://github.com/SamurAIGPT/llm-wiki-agent). Score 0.694. Open-source "personal knowledge base that builds and maintains itself" — wiki-ingest / wiki-query primitives that mirror Robin's OpenWiki mental model.
- **LinkedIn (David Bressler, PhD), 2026-07:** [Personal wikis, LLM-maintained knowledge bases, and agent memory systems all eventually hit the same question: How do you know the information in there is still accurate?](https://www.linkedin.com/posts/david-bressler_personal-wikis-llm-maintained-knowledge-activity-7486993623939678208-q4rL). Score 0.614. Adjacent commentary on knowledge-base freshness in agent-maintained wikis.
- **Reddit r/ClaudeAI, 2026-07-23:** [How many of you are running an LLM wiki with claude code?](https://www.reddit.com/r/ClaudeAI/comments/1v4rdiv/how_many_of_you_are_running_an_llm_wiki_with). Score 0.288 (31 upvotes, 26 comments). Community confirmation that OKF-formatted Obsidian wikis are a working pattern for Claude Code users.
- **BigDATAwire (Exabase), 2026-07-28:** [Exabase Reports State-of-the-Art Results on BEAM Memory Benchmark](https://www.hpcwire.com/bigdatawire/this-just-in/exabase-reports-state-of-the-art-results-on-beam-memory-benchmark). Score 0.567. Adjacent: BEAM-style memory benchmarks for agent memory engines.
**Robin relevance:** workflow-tooling, low priority — but the cluster is **substantially more corroborated than the prior HN-only signal**. Five distinct publishers (YouTube creator, SaaS vendor, GitHub, LinkedIn, Reddit) and one adjacent benchmark in the same week all converge on the same OKF + MCP shared-memory architecture. Combined with the existing `agent-memory-architecture` row's three HN Show HN items, the topic now has 8+ distinct sources. **Promote** `agent-memory-architecture` from `watchlist` to `source-backed` and refresh Last seen to 2026-07-28.
### 3Brain / Cellink / CellShot / installed-base / Hermes lanes — no new vendor-anchored evidence; Tavily answer-text mis-attribution recurs
- **3Brain CorePlate MEA 2026:** the Nature [portable semi-dry EEG device paper](https://www.nature.com/articles/s41598-026-52672-8) reappears at score 0.187. Tavily answer text again labels it "3Brain CorePlate MEA 2026 validated in a braincomputer interface study" — the underlying paper is about a portable EEG headset, **not 3Brain's MEA chips**. This is the fourth pull in a row with the same mis-attribution. Do not promote as 3Brain evidence.
- **Cellink BIO X bioprinter 2026:** Tavily answer text labels the Roche [ADLM 2026 intelligent lab solutions press release](https://www.biospace.com/press-releases/roche-showcases-intelligent-lab-solutions-and-high-precision-instruments-at-adlm-2026-to-help-laboratories-address-workforce-and-workflow-challenges) (0.082) as "Cellink BIO X bioprinter at ADLM 2026" — the underlying source is Roche, not Cellink. The remainder of the lane is industry context (Nova BiomedicalNanoCellect, Massive BioGELL, Lumafield Mars X-ray, RepligenBioLife, BioTechniques bi-weekly). All unrelated to Cellink BIO X / BIONOVA X / Lumen X.
- **CellShot / CellPick bioprinter 2026:** Tavily honestly says "the CellShot CellPick bioprinter 2026 is not directly mentioned in the provided data sources." Top hits are CCDx whole-cell genomic profiling (0.164), Nova BiomedicalNanoCellect (0.062), AI protein engineering model (0.059), Towards Healthcare cell-and-gene-therapy intelligence infrastructure (0.052), Pluristyx re-mention (0.042). No Femtobiomed vendor signal.
- **labs CelVivo ClinoStar installed base 2026:** no direct result. Cepheid GeneXpert third-generation ADLM 2026 (score 0.112) and Roche ADLM 2026 (0.143) dominate the top slots and are unrelated to CelVivo installed-base. Query phrasing continues to drift toward competitor/molecular-diagnostic content.
- **Hermes Agent MiniMax M3 changelog 2026:** Tavily answer text returns Apple product news ("Mismatched M6 and M5 Pro chips", iOS 26.6, POCO Launcher 7.50) — no Hermes Agent, no MiniMax M3, no Hermes changelog in the underlying URLs. Top hit: [MacRumors Next Mac Mini article](https://www.macrumors.com/2026/07/22/mac-mini-m6-m5-pro-chips-rumor/) at 0.074. The v0.19 Quicksilver signal from the prior pull remains the most recent Hermes row; this lane produced nothing new in this 24h window.
- **OpenWiki connectors Tavily RAGFlow 2026:** Tavily recall still broken. Returns AWWA ACE26 SmartBall X (0.025), Bizora advisory group / Billtrust MCP server (0.026), OpenTug shipping (0.017), Sunvega AI spatial-design workspace (0.016), RightShip maritime (0.016), Inland Tank-Barge Safety Guide (0.015). Only the Billtrust MCP server item is mildly adjacent (MCP-server ecosystem); the rest is unrelated to OpenWiki / Gitea / Wiki.js / RAGFlow / NocoDB / SeaFile. Recommend dropping this lane from future Tavily runs unless the query is rephrased to anchor on product names.
- **organ-on-chip pharma collaboration 2026:** the Nature [Gut-on-a-Chip culturomics paper](https://www.nature.com/articles/s44385-026-00099-1) (0.986) is the same item surfaced in the 2026-07-26 17:39 pull. Application-domain signal only — folds into the `class-organoid-3d-bioprinting` row without a new evidence note.
### Synthesis result
- **Two new scope-aligned findings:**
1. **China Order No. 818** — clinical-translation pathway for cell therapy + 3D bioprinting at qualified hospitals, effective 2026-05-01. Source-backed on a single primary source (BetaLife LinkedIn) with Tavily synthesis corroboration. Distinct from the existing `china-cde-cell-gene-therapy-rules-2026` item (classification vs clinical pathway). Promoted to `/themes.md` as new row `china-order-no-818-clinical-translation` and to `/commitments.md` as a verification item.
2. **LLM Wiki + OKF shared-memory cluster** — five Tavily sources + three prior HN sources all converge on Karpathy's LLM Wiki + Google OKF + MCP shared-memory architecture. Directly adjacent to OpenWiki's role. Promotes existing `agent-memory-architecture` row from `watchlist` to `source-backed`.
- **No new vendor-anchored evidence** on CelVivo, 3Brain, Cellink, CellShot/TriArm, or Hermes this pull. The prior vendor-anchored items (CelVivo+TheWell, Hermes v0.19 Quicksilver) remain on disk and referenceable; the Hermes row's Last seen is **not** refreshed because the underlying URLs in this pull returned Apple-product noise.
- **Tavily answer-text mis-attribution pattern persists** on 3Brain (4th pull), Cellink (4th pull), and Hermes (1st pull). This is a Tavily-side quality issue; treat Tavily answer text as untrusted and only the underlying URLs as evidence. Continued recommendation: narrow future pulls to vendor-name-anchored queries only.
- **OpenWiki / RAGFlow / agent-memory lane behavior changed.** The lane still produces zero OpenWiki/RAGFlow/SeaFile/NocoDB/Gitea results, but the **agent-personal-memory-wiki** lane is now high-signal for the OKF/LLM Wiki architecture — strong enough to promote the existing `agent-memory-architecture` row.