chore: daily update 2026-08-09
This commit is contained in:
OpenWiki Bot
@@ -59,6 +59,8 @@ The state diagram shows the canonical CelVivo → 3Brain workflow: 3D suspension
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- **Whitepaper: "Breaking the Bias" (2026, 16 pp)** — CelVivo's official vendor narrative on brain organoid long-term culture. Key data: ~110 day / 8 mm diameter brain organoid (Univ. Groningen, Trombetta-Lima); sc-RNA-seq 17,738 cells at Day 90 (Univ. Lausanne, Bagni); Day 30/45 dorsal forebrain comparison vs orbital shaker (Drexel, Qiang); hiPSC → cortical organoid + Omicron BA.5 (QIMR Berghofer, Stewart 2022). 4 patents: WO 2021/001472, WO 2021/245117, WO 2022/008292, WO 2022/144461. Full synthesis at [`/sources/literature-celvivo-brain-whitepaper-2026.md`](/sources/literature-celvivo-brain-whitepaper-2026.md).
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- **Bosnjakovic 2025 bioRxiv (PAH HepG2 3D spheroid, ClinoStar dynamic culture)** — 21-day maturation + 24h/96h BaP/BBF exposure; **4 metabolic markers (phenylalanine, TCA intermediates, GSH depletion, sphingolipid dysregulation) only appear in 3D, completely invisible in 2D**. Sales ammunition: "your 2D model is missing 100% of environmental toxicology early signals". Synthesis at [`/sources/literature-cel-bosnjakovic-2025-pah-deepread.md`](/sources/literature-cel-bosnjakovic-2025-pah-deepread.md).
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- **Miao 2025 Cell v2 (co-differentiation mesoderm + endoderm, vascularized lung/gut organoids, ClinoStar rotating culture)** — single 3D EB co-induction strategy yields **vHLPO with 7% ECs vs traditional HLPO 0%**, organ-specific endothelium + mesenchyme scRNA-seq validation, in-vivo functional integration with host circulation, FOXF1 mutation ACDMPV dual-pathology disease modeling. Product relevance: CelVivo ClinoStar rating 5 (co-differentiation depends on 3D EB self-organization in low-shear rotating culture — ClinoStar is the canonical hardware), HD-MEA rating 4, 3D bioprinting rating 3, patient-derived organoid drug screening rating 5. Synthesis at [`/sources/literature-miao-2025-cell-vascularization-v2-deepread.md`](/sources/literature-miao-2025-cell-vascularization-v2-deepread.md).
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- **Liu 2026 Nat Biomed Eng (shape-conformal porous framework for neural organoid e-phys, Rogers Lab)** — CelVivo ClinoStar rating 4 (organoid culture downstream of the shape-conformal framework; long-term maturation + functional readout is the canonical ClinoStar → HD-MEA workflow). Synthesis at [`/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md`](/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md). See 3Brain evidence for the HD-MEA read side.
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- **Sales ammunition kit (CelVivo pricing + 8 Protocols + 5 app notes + 5 brand/whitepapers)** — Demo kit `10005-6` lists at €300 (Global Distributor Price, with special discount). 8 ClinoReactor Protocols cover prepare / media change / gardening / plate config / rotation-speed / alginate embed / VitroGel embed. 5 application notes cover HepG2/C3A liver, FTC-133 thyroid, NCI-H69V SCLC, TNBC, ClinoStar vs Orbital Shaker. Synthesis at [`/sources/sales-ammunition.md`](/sources/sales-ammunition.md).
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- **260528_CS vs OS app note (2026-07-17 deep read)** — ClinoStar vs Orbital Shaker shear-stress comparison for long-term 3D construct performance; ClinoStar has lower shear + long-term growth + better consistency. This is the **vs-competitor killer document** for "why not use an orbital shaker" customer questions.
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- **111_Planimetry app note (2026-07-17 deep read)** — Planimetry measurements of spheroids in ClinoReactor using FIJI (open-source). Standard answer for "how to quantify spheroids".
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@@ -66,6 +68,8 @@ The state diagram shows the canonical CelVivo → 3Brain workflow: 3D suspension
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### 3Brain evidence
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- **Raji 2026 Mol Psychiatry (hMOs + 3Brain HD-MEA, 2026-07-27 deep read)** — WNT-modulated human midbrain organoids + 3Brain BioCAM DupleX + Accura-3D (4096 electrodes) + BrainWave 5. **TH+ 58% at 12 weeks** (vs 2D 18%, 3D static 32%). DA release 76 pg/mL (vs 2D 12, 3D static 28). α-synuclein PFF → DA neurons -35% / TH -40% / DA release -45% — establishes the **PD drug screening platform**. Shear-stress 15x lower than orbital shaking (0.13 dyn/cm² vs 2.03 dyn/cm²). Synthesis at [`/sources/literature-raji-2026-deepread.md`](/sources/literature-raji-2026-deepread.md).
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- **Liu 2026 Nat Biomed Eng (shape-conformal porous framework, full-coverage neural organoid e-phys, Rogers Lab)** — HD-MEA rating 5: **3000-8000 channels per organoid vs traditional MEA 200-1000 (10-50× improvement), >90% surface coverage vs 5-15%, weeks-long stable recording + bi-directional electrical + optogenetic stimulation, epilepsy + AD disease modeling**. The framework is the **direct next-generation design reference** for 3Brain's current 4096-electrode Accura-3D; Robin should sell Accura-3D as the existing best-in-class and Liu 2026 as the forward-looking 3D-coverage direction. Synthesis at [`/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md`](/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md). Tracks as `liu-2026-hd-mea-roadmap-implication` commitment (verify with 3Brain whether flexible-electronics / shape-conformal framework is on their roadmap).
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- **Sharma 2026 Cell Stem Cell (vascularized retinal organoids, RGC survival)** — HD-MEA rating 4: paper uses 60-channel MCS MEA2100-Lite; 3Brain HD-MEA is same-generation HD technology, technical route is transferable. The W31 ON/OFF/ON-OFF light-response recording paradigm is the kind of long-duration, multi-class recording where HD spatial resolution matters most. CelVivo ClinoStar rating 3 (vascular network regresses in static culture → ClinoStar low-shear route candidate). W18 RGC yield **18.2% vs ctrl-RO 1.21% (15× improvement)** through C3 endothelial monolayer integration. Synthesis at [`/sources/literature-sharma-2026-cell-stem-cell-vascularized-retinal-organoid-rgc-deepread.md`](/sources/literature-sharma-2026-cell-stem-cell-vascularized-retinal-organoid-rgc-deepread.md).
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- **3Brain Sample Holder Set / PressNet (UK GB2624872)** — Mechanical net-press device for CorePlate 1W/6W; load force 250–1250 µN. Recorded 2026-07-07 (untracked in vault). Carryover evidence in [`/sources/git-repo.md`](/sources/git-repo.md) Notable entities.
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- **3Brain end-customer dossiers** — 11+ dossiers under `03-Resources/End-Customers/` covering 神经所 (上海), 北京大学, 北京天坛医院, 浙大一附院, 中科院昆明动物所, 西南医科大学, 贵州医科大学, plus TCM accounts at 云南中医药大学 and 天津创新中药. Listed in [`/sources/git-repo.md`](/sources/git-repo.md) Notable entities.
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- **Vendor-channel strand (Tavily 2026-07-30 → 2026-08-03)** — 3Brain's official website + LinkedIn (booth 412 at ISSCR 2026; booth 4 at ELRIG Drug Discovery; Utrecht Summer School "Human Brain Models" course 2026-07-29). Tracks in `/commitments.md` as `3brain-coreplate-2026-conference-positioning` (verify which conference posts are current and pull application notes).
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@@ -73,6 +77,8 @@ The state diagram shows the canonical CelVivo → 3Brain workflow: 3D suspension
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## Cross-vendor workflow links
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- **CelVivo + 3Brain joint workflow** (from Raji 2026): hMOs are cultured in a **bioreactor** (CelVivo-class, low-shear rotating-wall) for 12 weeks; transplanted to **3Brain Accura-3D** (4096-electrode HD-MEA chip) for 24h spike-train recording via BrainWave 5. Two pieces of hardware from two vendors compose the **PD drug screening platform** Robin sells.
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- **CelVivo + 3Brain next-gen workflow** (from Liu 2026): the shape-conformal porous framework (Rogers Lab, next-gen HD-MEA design) records 3000-8000 channels per organoid vs current 4096 — **forward-looking direction** for the CelVivo → 3Brain pipeline. Track in `/commitments.md` as `liu-2026-hd-mea-roadmap-implication`.
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- **CelVivo + 3Brain vascularized organoid workflow** (from Miao 2025 v2 + Sharma 2026): vHLPO and vRO use single 3D EB co-induction (mesoderm+endoderm) or C3 endothelial monolayer integration. The vascular-like networks regress in static culture — **CelVivo ClinoStar low-shear rotating culture is the candidate route to extend maturation**. Functional readout remains 3Brain HD-MEA territory (60-channel MEA in Sharma; future HD-MEA for vascularized organoids).
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- **CelVivo + TheWell Bioscience xeno-free workflow** (Tavily 2026-07-21/23/25): TheWell's hydrogel-media workflow pages position **ClinoReactor as the scale-up vessel for apical-out organoids + hMSC expansion**. Tracks in `/commitments.md` as `celvivo-clinoreactor-thewell-bioscience-xeno-free` (verify whether sanctioned co-marketing).
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- **CelVivo + Femtobiomed** (small but complementary): Femtobiomed CellShot / CellPick / TriArm for hiPSC electroporation upstream of CelVivo 3D culture.
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@@ -101,6 +107,9 @@ The state diagram shows the canonical CelVivo → 3Brain workflow: 3D suspension
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| What is ClinoReactor's pricing? | [`/sources/sales-ammunition.md`](/sources/sales-ammunition.md) |
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| What does the CelVivo brain organoid whitepaper actually say? | [`/sources/literature-celvivo-brain-whitepaper-2026.md`](/sources/literature-celvivo-brain-whitepaper-2026.md) |
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| What is Raji 2026's PD drug screening story? | [`/sources/literature-raji-2026-deepread.md`](/sources/literature-raji-2026-deepread.md) |
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| What is Miao 2025's vascularized lung/gut organoid story? | [`/sources/literature-miao-2025-cell-vascularization-v2-deepread.md`](/sources/literature-miao-2025-cell-vascularization-v2-deepread.md) |
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| What is Liu 2026's shape-conformal neural organoid e-phys story? | [`/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md`](/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md) |
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| What is Sharma 2026's vascularized retinal organoid RGC story? | [`/sources/literature-sharma-2026-cell-stem-cell-vascularized-retinal-organoid-rgc-deepread.md`](/sources/literature-sharma-2026-cell-stem-cell-vascularized-retinal-organoid-rgc-deepread.md) |
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| What distributors am I actually working with? | [`/sources/agents.md`](/sources/agents.md) |
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| Which Chinese dealers carry our brand? | [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md) |
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| What regulatory shifts affect our Chinese pharma deals? | [`/commitments.md`](/commitments.md) China CDE / Order No. 818 / China CGT items |
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@@ -48,6 +48,7 @@ This is the synthesis page for **3D 生物打印** — Robin's 3D bioprinting pr
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The 3D bioprinting lane also captures application-domain papers that bioprint scaffolds for organoid culture — these are **vendor-adjacent** signals that fold into the [`/themes/01-organoid-equipment.md`](/themes/01-organoid-equipment.md) organoid culture theme rather than into Cellink hardware sales:
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- **Liu 2026 Nat Biomed Eng (shape-conformal porous framework, Rogers Lab, 2026-08-08 deep read)** — flexible-electronics microlattice fabrication as a 3D-bioprinting-adjacent technology for neural organoid scaffolds. **3D bioprinting rating 5** — the microlattice fabrication technique depends on 3D printing-class resolution (Cellink BIO X / BIONOVA X / Lumen X cannot directly print at this resolution today, but the field direction is clear: future bioprinters will integrate flexible-electronics fabrication). The framework records 3000-8000 channels per organoid (>90% surface coverage, weeks-long stable recording, epilepsy + AD disease modeling) — Robin should pitch Liu 2026 to Cellink to understand whether BIONOVA X or Lumen X can fabricate flexible-electronics-compatible microlattices. Synthesis at [`/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md`](/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md). First entry in the new NocoDB table `Robin_Picked_Papers` (created 2026-08-08).
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- **MDPI Cells 2026-07-27** — "Rapid Volumetric Bioprinting Coupled with Dynamic Perfusion Enhances Human Hepatic Organoid Toxicity Testing"
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- **GEN 2026-07-29** — "Large Bioprinted Tissues Get a Precision Boost"
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- **HepatoBiliary Surgery and Nutrition 2026-08-01** — "Spatial architecture and dynamic surveillance: 3D bioprinting and microfluidics converge" (strongest same-week cross-anchor between organ-on-chip and 3D-bioprinting)
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@@ -94,4 +95,5 @@ The bioprinting theme is **evidence-light compared to theme 1 (organoid-equipmen
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| Is the New Lumen X product release verified? | [`/commitments.md`](/commitments.md) `cellink-volumetric-lumen-x-release` |
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| Are there BIO X Gen 3 / BIO X6 customer installs in China? | [`/commitments.md`](/commitments.md) `cellink-bio-x-gen3-customer-evidence` |
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| What distributors carry Cellink in China? | [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md) |
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| What 3D bioprinted-organoid reviews have come out this month? | [`/sources/web-search.md`](/sources/web-search.md) 2026-07-29 / 2026-07-30 / 2026-08-03 pulls |
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| What 3D bioprinted-organoid reviews have come out this month? | [`/sources/web-search.md`](/sources/web-search.md) 2026-07-29 / 2026-07-30 / 2026-08-03 pulls |
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| What is Liu 2026's shape-conformal neural organoid framework story (microlattice + flexible electronics)? | [`/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md`](/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md) |
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+14
-19
@@ -19,30 +19,29 @@ This is the synthesis page for **AI Agent 工具** — Robin's daily-driver stac
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## Agent stack architecture
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<!-- openwiki: mermaid parse failed and this diagram was converted to a text fence so it does not break rendering. Fix the diagram source and restore the mermaid fence. Parser error: Heuristic: an unescaped angle bracket inside a label breaks rendering; rephrase the label. -->
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```text
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```mermaid
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flowchart TD
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User[Robin · desktop / mobile]
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subgraph DesktopWSL[WSL · primary host]
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Hermes[Hermes Agent v0.19 Quicksilver]
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Cron1["cron 02:00<br/>openwiki-update.sh"]
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Cron1["cron 02:00 (openwiki-update.sh)"]
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end
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subgraph DesktopPC[Windows desktop · secondary]
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MiniMaxCode[MiniMax code<br/>+ 4 bridge skills]
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MiniMaxCode["MiniMax code (+ 4 bridge skills)"]
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CodexCLI[Codex CLI fallback]
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end
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subgraph Remote[ITX 24h host · future]
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ITXHermes[Hermes Agent<br/>on Ubuntu 22.04]
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ITXHermes["Hermes Agent (on Ubuntu 22.04)"]
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end
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subgraph Memory[Memory substrate]
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OpenWiki[(OpenWiki<br/>local markdown wiki)]
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Gitea[Gitea public mirror<br/>10.10.10.254:3080]
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OpenWiki[("OpenWiki (local markdown wiki)")]
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Gitea["Gitea public mirror (10.10.10.254:3080)"]
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end
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subgraph KB[Knowledge backends · NAS]
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RAGFlowKB[RAGFlow<br/>18 KB · 32709 docs]
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NocoDBDB[NocoDB<br/>13 lit tables]
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SeaFileStore[SeaFile<br/>4 repos · 77 GB]
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WikiJS[Wiki.js<br/>1500+ pages]
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RAGFlowKB["RAGFlow (18 KB · 32709 docs)"]
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NocoDBDB["NocoDB (13 lit tables)"]
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SeaFileStore["SeaFile (4 repos · 77 GB)"]
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WikiJS["Wiki.js (1500+ pages)"]
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end
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subgraph LLM[Local inference · see theme 04]
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MiniMaxM3[MiniMax-M3 1M context]
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@@ -96,8 +95,7 @@ The architecture shows three agent surfaces sharing the OpenWiki memory substrat
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- **OpenWiki = LangChain 7/10 open-source "personal brain" framework.** Local markdown wiki rooted at `~/.openwiki/wiki`, mirrored to Gitea public `http://10.10.10.254:3080/Robin/openwiki-wiki`. Cron pipeline: every night 02:00 `openwiki-update.sh` (HN + Tavily + git-repo + M3 agent synthesis) → commit → push to Gitea. Every 02:30 `openwiki-update-sources.sh` (NocoDB + SeaFile + Wiki.js + RAGFlow health checks) → commit → push.
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- **Five canonical synthesis pages** — [`/quickstart.md`](/quickstart.md), [`/themes.md`](/themes.md), [`/commitments.md`](/commitments.md), [`/open-questions.md`](/open-questions.md), [`/personal-logistics.md`](/personal-logistics.md). Five detailed theme pages under [`/themes/`](/themes/).
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- **Evidence layer** — 21 source pages under [`/sources/`](/sources/), one per active connector or subsystem.
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<!-- openwiki: broken internal link [/sources/README-ACTIVATION.md] file "/sources/README-ACTIVATION.md" does not exist. Fix the href or restore the target, then delete this comment. -->
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- **Activation manual:** [`/sources/README-ACTIVATION.md`](/sources/README-ACTIVATION.md) (2026-07-27 update). 8 sections covering TL;DR / connectors not yet on / daily operations / what Robin manually does / what Robin never touches / cross-tool cheat sheet / today's real system status / changes from 7-26 / next steps.
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- **Activation manual:** [`/README-ACTIVATION.md`](/README-ACTIVATION.md) (2026-07-27 update). 8 sections covering TL;DR / connectors not yet on / daily operations / what Robin manually does / what Robin never touches / cross-tool cheat sheet / today's real system status / changes from 7-26 / next steps.
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- **Cheat sheet:** [`/sources/OpenWiki速查手册.md`](/sources/OpenWiki速查手册.md) (2026-07-27 one-shot reference for talking to colleagues / boss / agents about what OpenWiki is).
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## Supporting toolchain (AI-side)
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@@ -106,8 +104,7 @@ The architecture shows three agent surfaces sharing the OpenWiki memory substrat
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- **Master template:** [`/sources/ldr-report-template.md`](/sources/ldr-report-template.md) — 8 铁律 + 3 trigger modes (精简 4 步 vs 完整 8 步 vs 自动) + 5-section report template (做什么 / 3 发现 / 4 维产品对接 / 局限 / 转发语+落款+PDF). Total report length 800–1500 characters.
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- **SOP lessons:** [`/sources/2026-07-27-4-27-sop-vs-implementation.md`](/sources/2026-07-27-4-27-sop-vs-implementation.md) — 9-step SOP vs 7-27 凭印象实操 comparison. PyMuPDF xref dedup + 30KB filter + p1 logo 剔除. NocoDB v1 + JSON body (范本 v2 fails 3x). SeaFile `?dl=1` suffix required. 3-frame SeaFile image 嵌入 markdown.
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<!-- openwiki: broken internal link [/sources/memory-2026-07-16-tools-final.md] file "/sources/memory-2026-07-16-tools-final.md" does not exist. Fix the href or restore the target, then delete this comment. -->
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- **Toolchain打通战报:** [`/sources/memory-2026-07-16-tools-final.md`](/sources/memory-2026-07-16-tools-final.md) — 2026-07-16 OpenWiki + Gitea + NocoDB + RAGFlow + Wiki.js + MiniMax code 端到端打通. 9 链路.
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- **Toolchain打通战报:** [`/memory-2026-07-16-tools-final.md`](/memory-2026-07-16-tools-final.md) — 2026-07-16 OpenWiki + Gitea + NocoDB + RAGFlow + Wiki.js + MiniMax code 端到端打通. 9 链路.
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### Remote access (RustDesk)
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@@ -141,11 +138,9 @@ The architecture shows three agent surfaces sharing the OpenWiki memory substrat
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| Question | Go to |
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| --- | --- |
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| What is OpenWiki and how do I use it? | [`/sources/OpenWiki速查手册.md`](/sources/OpenWiki速查手册.md) |
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<!-- openwiki: broken internal link [/sources/README-ACTIVATION.md] file "/sources/README-ACTIVATION.md" does not exist. Fix the href or restore the target, then delete this comment. -->
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| What connectors does OpenWiki have? | [`/sources/README-ACTIVATION.md`](/sources/README-ACTIVATION.md) |
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| What connectors does OpenWiki have? | [`/README-ACTIVATION.md`](/README-ACTIVATION.md) |
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| What is the LDR report format? | [`/sources/ldr-report-template.md`](/sources/ldr-report-template.md) |
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| What are the LDR SOP lessons? | [`/sources/2026-07-27-4-27-sop-vs-implementation.md`](/sources/2026-07-27-4-27-sop-vs-implementation.md) |
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| How is RustDesk configured? | [`/sources/rustdesk-sop.md`](/sources/rustdesk-sop.md) |
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<!-- openwiki: broken internal link [/sources/memory-2026-07-16-tools-final.md] file "/sources/memory-2026-07-16-tools-final.md" does not exist. Fix the href or restore the target, then delete this comment. -->
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| What did Robin do on 2026-07-16 (toolchain通)? | [`/sources/memory-2026-07-16-tools-final.md`](/sources/memory-2026-07-16-tools-final.md) |
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| What did Robin do on 2026-07-16 (toolchain通)? | [`/memory-2026-07-16-tools-final.md`](/memory-2026-07-16-tools-final.md) |
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| What is the ITX 24h host build? | [`/commitments.md`](/commitments.md) `itx-24h-host-build-2026-q3` |
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+21
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@@ -19,31 +19,30 @@ This is the synthesis page for **本地大模型部署** — Robin's local infer
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## Local-LLM fleet architecture
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<!-- openwiki: mermaid parse failed and this diagram was converted to a text fence so it does not break rendering. Fix the diagram source and restore the mermaid fence. Parser error: Heuristic: an unescaped angle bracket inside a label breaks rendering; rephrase the label. -->
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```text
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```mermaid
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flowchart TD
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subgraph Desktop["Desktop · 192.168.192.67"]
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OllamaServe["Ollama serve<br/>:11434"]
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QwenV["qwen2.5vl:7b<br/>(vision)"]
|
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NomicE["nomic-embed-text<br/>(embed)"]
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LMStudio["LM Studio<br/>:7997"]
|
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BgeM3LM["BAAI/bge-m3<br/>(embed via LM Studio)"]
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Reranker["bge-reranker<br/>:8090"]
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OllamaServe["Ollama serve :11434"]
|
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QwenV["qwen2.5vl:7b (vision)"]
|
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NomicE["nomic-embed-text (embed)"]
|
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LMStudio["LM Studio :7997"]
|
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BgeM3LM["BAAI/bge-m3 (embed via LM Studio)"]
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Reranker["bge-reranker :8090"]
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OllamaServe --> QwenV
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OllamaServe --> NomicE
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LMStudio --> BgeM3LM
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end
|
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subgraph NAS["NAS · 10.10.10.254"]
|
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RAGFlow["RAGFlow KB<br/>:9980<br/>18 KB / 32,709 docs"]
|
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NocoDB["NocoDB<br/>:8081<br/>13 lit tables"]
|
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SeaFile["SeaFile<br/>:9898<br/>4 repos / 77 GB"]
|
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WikiJS["Wiki.js<br/>:3000<br/>~1500 pages"]
|
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Feishu["Feishu mail<br/>IMAP poll (awaiting creds)"]
|
||||
RAGFlow["RAGFlow KB :9980 (18 KB / 32,709 docs)"]
|
||||
NocoDB["NocoDB :8081 (13 lit tables)"]
|
||||
SeaFile["SeaFile :9898 (4 repos / 77 GB)"]
|
||||
WikiJS["Wiki.js :3000 (~1500 pages)"]
|
||||
Feishu["Feishu mail IMAP poll (awaiting creds)"]
|
||||
end
|
||||
subgraph Agents["Agents (see theme 03)"]
|
||||
Hermes[Hermes Agent]
|
||||
MiniMaxCode[MiniMax code]
|
||||
CronDaily["cron 02:30<br/>update-sources.sh"]
|
||||
CronDaily["cron 02:30 update-sources.sh"]
|
||||
end
|
||||
|
||||
RAGFlow -.embedding.-> OllamaServe
|
||||
@@ -59,7 +58,7 @@ flowchart TD
|
||||
CronDaily -->|count refresh| NocoDB
|
||||
CronDaily -->|count refresh| SeaFile
|
||||
CronDaily -->|count refresh| WikiJS
|
||||
QwenV -.vision OCR.-> LDR["LDR SOP<br/>(theme 05)"]
|
||||
QwenV -.vision OCR.-> LDR["LDR SOP (theme 05)"]
|
||||
```
|
||||
|
||||
The diagram shows the three local inference services (Ollama serve, LM Studio, bge-reranker) feeding the RAGFlow KB layer, with the four NAS subsystems (NocoDB / SeaFile / Wiki.js / Feishu mail) attached at the metadata / file / published-deep-read / IMAP layer. All three inference services and all four subsystems are probed nightly by `update-sources.sh` at 02:30.
|
||||
@@ -147,14 +146,13 @@ Each subsystem has its own source page; the bullets below are the cross-agent qu
|
||||
|
||||
Two cron pipelines drive the local-LLM fleet:
|
||||
|
||||
<!-- openwiki: mermaid parse failed and this diagram was converted to a text fence so it does not break rendering. Fix the diagram source and restore the mermaid fence. Parser error: Heuristic: an unescaped angle bracket inside a label breaks rendering; rephrase the label. -->
|
||||
```text
|
||||
```mermaid
|
||||
flowchart LR
|
||||
subgraph Cron1["02:00 daily · openwiki-update.sh"]
|
||||
HN[Hacker News ingest]
|
||||
Tavily[Tavily web search ingest]
|
||||
GitRepo[git-repo ingest]
|
||||
M3["M3 agent synthesis<br/>writes /themes + /commitments"]
|
||||
M3["M3 agent synthesis (writes /themes + /commitments)"]
|
||||
end
|
||||
subgraph Cron2["02:30 daily · openwiki-update-sources.sh"]
|
||||
NocoDBP[NocoDB count refresh]
|
||||
@@ -166,12 +164,12 @@ flowchart LR
|
||||
FeishuP[Feishu INBOX poll]
|
||||
end
|
||||
subgraph Runtime["Local inference runtime"]
|
||||
OllamaEmbed["Ollama :11434<br/>nomic-embed-text"]
|
||||
LMStudioEmbed["LM Studio :7997<br/>BAAI/bge-m3"]
|
||||
OllamaEmbed["Ollama :11434 (nomic-embed-text)"]
|
||||
LMStudioEmbed["LM Studio :7997 (BAAI/bge-m3)"]
|
||||
RerankerSvc["bge-reranker :8090"]
|
||||
end
|
||||
subgraph Sink["Wiki sink"]
|
||||
OpenWiki[OpenWiki<br/>commit and push Gitea]
|
||||
OpenWiki[OpenWiki (commit and push Gitea)]
|
||||
end
|
||||
Cron1 --> OpenWiki
|
||||
Cron2 --> OpenWiki
|
||||
@@ -213,7 +211,7 @@ The 02:00 cron pulls 3 connectors and runs M3 agent synthesis (writes to `/theme
|
||||
| What is the Feishu mail integration status? | [`/sources/feishu-mail.md`](/sources/feishu-mail.md) |
|
||||
| How are the LDR PDFs and figures uploaded to SeaFile? | [`/sources/ldr-report-template.md`](/sources/ldr-report-template.md) §4-5 |
|
||||
| What did the 7-27 SOP-vs-implementation pass reveal about the service-down incident? | [`/sources/2026-07-27-4-27-sop-vs-implementation.md`](/sources/2026-07-27-4-27-sop-vs-implementation.md) §4 |
|
||||
<!-- openwiki: broken internal link [/sources/README-ACTIVATION.md] file "/sources/README-ACTIVATION.md" does not exist. Fix the href or restore the target, then delete this comment. -->
|
||||
| What is the daily cron pipeline? | [`/sources/README-ACTIVATION.md`](/sources/README-ACTIVATION.md) §3 |
|
||||
|
||||
| What is the daily cron pipeline? | [`/README-ACTIVATION.md`](/README-ACTIVATION.md) §3 |
|
||||
| How does MiniMax code read this stack? | [`/sources/OpenWiki速查手册.md`](/sources/OpenWiki速查手册.md) §5.8 |
|
||||
| How does the agent layer depend on this fleet? | [`/themes/03-ai-agents.md`](/themes/03-ai-agents.md) |
|
||||
+63
-45
@@ -20,23 +20,22 @@ This is the synthesis page for **Robin 个人研究项目** — the durable body
|
||||
|
||||
## Research output — data model
|
||||
|
||||
<!-- openwiki: mermaid parse failed and this diagram was converted to a text fence so it does not break rendering. Fix the diagram source and restore the mermaid fence. Parser error: Heuristic: an unescaped angle bracket inside a label breaks rendering; rephrase the label. -->
|
||||
```text
|
||||
```mermaid
|
||||
erDiagram
|
||||
VAULT["Obsidian vault<br/>(1a81e485)"] ||--o{ DEEPREADS["Deep-read notes<br/>~1,202"]
|
||||
VAULT ||--o{ TRAIN["Sales training<br/>(CelVivo赋能培训 v1-v9)"]
|
||||
VAULT ||--o{ SALES["Active sales pipeline<br/>(惠百生物 PO + 中间商)"]
|
||||
VAULT ||--o{ CRM["Distributor profiles<br/>(董慧群 + 待补)"]
|
||||
VAULT ||--o{ ENDCUST["End-customer dossiers<br/>(11+ 神经/中药/肿瘤所)"]
|
||||
VAULT ||--o{ INDUSTRIAL["Industrial customers<br/>(CelVivo中国工业客户开发)"]
|
||||
VAULT ||--o{ MEMORY["Daily + weekly reports<br/>(memory/ 147 .md)"]
|
||||
VAULT ||--o{ ITX["ITX 24h host build<br/>(untracked)"]
|
||||
VAULT["Obsidian vault (d7df3830)"] ||--o{ DEEPREADS["Deep-read notes ~1,202"]
|
||||
VAULT ||--o{ TRAIN["Sales training (CelVivo赋能培训 v1-v9)"]
|
||||
VAULT ||--o{ SALES["Active sales pipeline (惠百生物 PO + 中间商)"]
|
||||
VAULT ||--o{ CRM["Distributor profiles (董慧群 + 待补)"]
|
||||
VAULT ||--o{ ENDCUST["End-customer dossiers (11+ 神经/中药/肿瘤所)"]
|
||||
VAULT ||--o{ INDUSTRIAL["Industrial customers (CelVivo中国工业客户开发)"]
|
||||
VAULT ||--o{ MEMORY["Daily + weekly reports (memory/ 147 .md)"]
|
||||
VAULT ||--o{ ITX["ITX 24h host build (untracked)"]
|
||||
|
||||
DEEPREADS }o--|| VENDOR["Vendor mapping"]
|
||||
VENDOR ||--|{ CelVivo["CelVivo<br/>(ClinoStar / ClinoReactor)"]
|
||||
VENDOR ||--|{ ThreeBrain["3Brain<br/>(BioCAM / Accura-3D / CorePlate)"]
|
||||
VENDOR ||--|{ Cellink["Cellink<br/>(BIO X / BIONOVA X / Lumen X)"]
|
||||
VENDOR ||--|{ Femtobiomed["Femtobiomed<br/>(CellShot / TriArm / CellPick)"]
|
||||
VENDOR ||--|{ CelVivo["CelVivo (ClinoStar / ClinoReactor)"]
|
||||
VENDOR ||--|{ ThreeBrain["3Brain (BioCAM / Accura-3D / CorePlate)"]
|
||||
VENDOR ||--|{ Cellink["Cellink (BIO X / BIONOVA X / Lumen X)"]
|
||||
VENDOR ||--|{ Femtobiomed["Femtobiomed (CellShot / TriArm / CellPick)"]
|
||||
|
||||
SALES }o--|| CelVivo
|
||||
CRM }o--|| CelVivo
|
||||
@@ -49,17 +48,17 @@ The diagram shows Robin's research substrate: a single Obsidian vault with 8 buc
|
||||
|
||||
## Knowledge substrate: Obsidian vault
|
||||
|
||||
Snapshot from [`/sources/git-repo.md`](/sources/git-repo.md) (last fetch 2026-08-03T18:13:23Z):
|
||||
Snapshot from [`/sources/git-repo.md`](/sources/git-repo.md) (last fetch 2026-08-08T18:11:31Z):
|
||||
|
||||
| Field | Value |
|
||||
| --- | --- |
|
||||
| Repo path | `/mnt/c/Users/20864/.openclaw/workspace` |
|
||||
| Repo path | `/home/ldw/workspace` |
|
||||
| Branch | `main` |
|
||||
| HEAD | `1a81e485b6f8a4496122464f1151702d09f03cf0` (2026-07-29) |
|
||||
| Ahead of origin/main | 9 commits (un-pushed as of fetch) |
|
||||
| HEAD | `d7df3830a28a48b0129a46729ab2357e231a2ec5` (2026-08-08) |
|
||||
| Ahead of origin/main | 9 commits new since 2026-08-03 fetch (Fernandez Vallone 2026 + Microbioreactor 2026 + Liu 2026 v2-v11 + 4 经销商 hook 升级); plus 19 untracked files in working tree |
|
||||
| Auth | local path only — no remote, no credentials |
|
||||
| Working-tree state | dirty (1 nested-submodule + 1 untracked dir + 5 untracked files) |
|
||||
| Raw manifest | `~/.openwiki/connectors/git-repo/raw/2026-08-03T18-13-23-151Z/manifest.json` |
|
||||
| Working-tree state | dirty (1 nested-submodule + 1 untracked dir + 19 untracked files including 8 new `02-Clients/Agents/区域-2026-0807.md`) |
|
||||
| Raw manifest | `~/.openwiki/connectors/git-repo/raw/2026-08-08T18-11-31-856Z/manifest.json` |
|
||||
|
||||
### Vault navigation index (top-level folders)
|
||||
|
||||
@@ -146,8 +145,7 @@ From [`/sources/ldr-report-template.md`](/sources/ldr-report-template.md) (Robin
|
||||
| 3. 9 项强制 + 创新点/局限性/学术启示 3 段 | 7-27 教训 (2 篇缺 3 段) | 模板 §3 |
|
||||
| 4. SeaFile URL hostname `fb.biokingdom.top` | 7-27 教训 (5 URL 错) | 验证 share-link 真能开 |
|
||||
| 5. NocoDB v1 + JSON body (范本 v2 失败 3 次) | 7-27 Tasevska 入库 | `POST /api/v1/db/data/wzg1wtad/p2z4g0s687axyvu/{table_id}` |
|
||||
<!-- openwiki: broken internal link [url] file "url" does not exist. Fix the href or restore the target, then delete this comment. -->
|
||||
| 6. 3 张真图 `![]()` (SeaFile URL), 不**只**文字图说啥 | 7-27 教训 | `!\[alt\](url)` markdown |
|
||||
| 6. 3 张真图 `![]()` (SeaFile URL), 不**只**文字图说啥 | 7-27 教训 | markdown image syntax (`alt text` + parenthesized URL) |
|
||||
| 7. 报告路径 `journal-year-topic` (4-27 SOP 范本) | 7-27 教训 | `ejps-2025-hctz-sse-3d-printing` 风格 |
|
||||
| 8. 精简 4 步 vs 完整 8 步按 Robin 信号自动判断 | 7-27 实战 | 模板 §2 |
|
||||
|
||||
@@ -172,13 +170,22 @@ From [`/sources/ldr-report-template.md`](/sources/ldr-report-template.md) (Robin
|
||||
| Hodge 2025 RegenMed | Ronawk Bio-Block (KB 0 命中) | `04-Literature/Deep-Reads/RegenMed/2026-07-28_Hodge_2025_RegenMed_MSC_3D_Bio-Block.md` | (not yet synthesized to `/sources/`) |
|
||||
| Lee 2025 Front Vet Sci | (no vendor) | `04-Literature/Deep-Reads/Other/2026-07-28_Lee_2025_FrontVetSci_canine_MSC_3D_spheroid.md` | (not yet synthesized) |
|
||||
| Parate 2020 SCRT | (no vendor) | `04-Literature/Deep-Reads/Other/2026-07-28_Parate_2020_SCRT_PEMF_MSC_paracrine_cartilage.md` | (not yet synthesized) |
|
||||
| Sharma 2026 Cell Stem Cell (2026-08-08 flywheel-sync) | 3Brain + CelVivo adjacent | `/home/ldw/workspace/retinal_organoid_deep_read_2026-08-07.md` | [`/sources/literature-sharma-2026-cell-stem-cell-vascularized-retinal-organoid-rgc-deepread.md`](/sources/literature-sharma-2026-cell-stem-cell-vascularized-retinal-organoid-rgc-deepread.md) |
|
||||
| Miao 2025 Cell v2 (2026-08-08 flywheel-sync) | CelVivo (ClinoStar rating 5) | `/home/ldw/workspace/Miao2025_Cell_v2.md` | [`/sources/literature-miao-2025-cell-vascularization-v2-deepread.md`](/sources/literature-miao-2025-cell-vascularization-v2-deepread.md) |
|
||||
| Liu 2026 Nat Biomed Eng (2026-08-08 flywheel-sync) | 3Brain (HD-MEA rating 5) + Cellink (microlattice rating 5) | `/home/ldw/workspace/Liu2026_NBME_shape_conformal_organoid.md` | [`/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md`](/sources/literature-liu-2026-nbme-shape-conformal-organoid-deepread.md) |
|
||||
|
||||
## Recent 30-day research output (mtime 2026-06-16 → 2026-07-28)
|
||||
## Recent 30-day research output (mtime 2026-06-16 → 2026-08-08)
|
||||
|
||||
From [`/sources/literature.md`](/sources/literature.md) last sync, broken out by vendor and date:
|
||||
|
||||
| Date | DOI / slug | Vendor | Topic |
|
||||
| --- | --- | --- | --- |
|
||||
| 2026-08-08 | `10.3390/cells15110963` (Fernandez Vallone 2026) | (NAMs adjacent, hiPSC brain organoid) | THSDC chemical evaluation platform using hiPSC brain organoids (Cells, v2 5 张真图 + 双 H1; Wiki.js Id 1698) |
|
||||
| 2026-08-08 | `10.3389/fbioe.2026.1854988` (Rosero 2026) | CelVivo + Cellink + FemtoBiomed adjacent | Microbioreactor design Mini Review (Front Bioeng Biotechnol; 6× productivity vs T-flask; 4 applications: CAR-T / mAb / iPSC / organoid) |
|
||||
| 2026-08-08 | `10.1038/s41551-026-01620-y` (Liu 2026) | 3Brain (HD-MEA rating 5) + Cellink (microlattice rating 5) | Shape-conformal porous framework for full-coverage neural organoid e-phys — Rogers Lab, Nat Biomed Eng |
|
||||
| 2026-08-08 | `10.1016/j.cell.2025.05.041` (Miao 2025 v2) | CelVivo (ClinoStar rating 5) | Co-development mesoderm+endoderm for vascularized lung/gut organoids (Cell v2) |
|
||||
| 2026-08-08 | `10.1016/j.stem.2025.12.013` (Sharma 2026) | 3Brain (HD-MEA rating 4) + CelVivo (ClinoStar rating 3) | Vascularized retinal organoid RGC survival (Cell Stem Cell) |
|
||||
| 2026-08-06 | `10.1038/s41467-024-44732-2` (Parfitt 2024) | CelVivo + 3Brain adjacent | DJ1 LOF midbrain organoid PD model — α-syn via astrocyte lysosomal degradation (Nat Commun, untracked) |
|
||||
| 2026-07-29 | Organoids for disease modeling and treatment 2026 综述 (PMID 41545895, PMC12828948) | review | Exp Hematol Oncol 2026 — 190 项临床试验 + 4 大瓶颈 |
|
||||
| 2026-07-28 | `10.1080_17460751.2025.2572177` (Hodge 2025) | Ronawk Bio-Block | MSC longevity 4-week comparison |
|
||||
| 2026-07-28 | `10.3389/fvets.2025.1500267` (Lee 2025) | (no vendor) | canine adipose MSC 3D spheroid |
|
||||
@@ -197,14 +204,14 @@ From [`/sources/literature.md`](/sources/literature.md) last sync, broken out by
|
||||
|
||||
By vendor (30-day mtime):
|
||||
|
||||
| Vendor | Most recent |
|
||||
| --- | --- |
|
||||
| CelVivo | 2026-07-17 (CS vs OS + Planimetry) |
|
||||
| 3Brain | 2026-07-27 (Raji 2026) |
|
||||
| Cellink | 2026-07-27 (Tasevska 2025) |
|
||||
| Adjacent (no vendor) | 2026-07-29 (Organoids 2026 综述) |
|
||||
| Vendor | Most recent | 2026-08-08 additions |
|
||||
| --- | --- | --- |
|
||||
| CelVivo | 2026-08-08 (Miao 2025 v2 — ClinoStar rating 5) | +Miao 2025 v2 (ClinoStar co-differentiation), +Sharma 2026 (ClinoStar rating 3 adjacent), +Liu 2026 (ClinoStar rating 4 adjacent) |
|
||||
| 3Brain | 2026-08-08 (Liu 2026 — HD-MEA rating 5) | +Liu 2026 (shape-conformal framework, next-gen HD-MEA), +Sharma 2026 (HD-MEA rating 4 adjacent) |
|
||||
| Cellink | 2026-07-27 (Tasevska 2025) | +Liu 2026 (microlattice fabrication rating 5 adjacent) |
|
||||
| Adjacent (no vendor) | 2026-08-08 (Sharma 2026 retinal vascularization) | +Sharma 2026 (retinal organoid application domain) |
|
||||
|
||||
The pipeline is **vendor-balanced** — CelVivo, 3Brain, Cellink each have a recent deep read, and the broad organoid corpus is sustained by Ronawk Bio-Block, canine MSC, PEMF MSC paracrine, and the 2026 综述.
|
||||
The pipeline is **vendor-balanced** — CelVivo, 3Brain, Cellink each have a recent deep read, and today's flywheel-sync (2026-08-08) adds **3 papers spanning all 3 primary vendors + the retinal organoid application domain** (Sharma), all 3 rated 4-5 on at least one vendor's product line. The **first entry in the new NocoDB table `Robin_Picked_Papers`** is Liu 2026 (created 2026-08-08 per Robin instruction to capture papers Robin hand-picks / provides outside the regular PubMed triage).
|
||||
|
||||
## Sales ammunition pipeline
|
||||
|
||||
@@ -230,30 +237,39 @@ Per `/sources/git-repo.md` §"Notable entities", `06-Sales/Content/Training-Mate
|
||||
|
||||
The version progression is `基础 → 5大管线 → 深度版 → 终稿修正 → 销量仅看` — the cluster is iterated in place, not committed. See [`/sources/vault-mtime-snapshot-2026-07-16.md`](/sources/vault-mtime-snapshot-2026-07-16.md) for the latest mtime census (CelVivo_销售培训_PPT_v9 = 2026-06-26 14:13).
|
||||
|
||||
## China distributor map (261 dealers across 7 regions)
|
||||
## China distributor map (259 dealers across 7 regions — 2026-08-07 baseline)
|
||||
|
||||
From [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md) (Hermes整理, 2026-08-07):
|
||||
From [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md) (Hermes整理, 2026-08-07; **replaces 2026-07-24 baseline of 261 dealers**):
|
||||
|
||||
| Region | Count | Share | Main city |
|
||||
| --- | ---: | ---: | --- |
|
||||
| 华北 | 74 | 28.4% | 北京 (54) |
|
||||
| 华东 | 68 | 26.1% | 上海 (53) |
|
||||
| 华南 | 62 | 23.8% | 广州 (44) |
|
||||
| 山东 | 25 | 9.6% | 济南 (22) |
|
||||
| 湖北 | 19 | 7.3% | 武汉 (12) |
|
||||
| 西北 | 6 | 2.3% | 西安 (6) |
|
||||
| 西南 | 7 | 2.7% | 重庆 (3) |
|
||||
| **TOTAL** | **261** | 100% | — |
|
||||
| Region | 8-07 count | 7-24 count | Δ | Share | Main city |
|
||||
| --- | ---: | ---: | ---: | ---: | --- |
|
||||
| 华北 | 72 | 74 | -2 | 27.8% | 北京 (54) |
|
||||
| 华东 | 68 | 68 | 0 | 26.3% | 上海 (53) |
|
||||
| 华南 | 62 | 62 | 0 | 23.9% | 广州 (44) |
|
||||
| 山东 | 25 | 25 | 0 | 9.7% | 济南 (22) |
|
||||
| 湖北 | 19 | 19 | 0 | 7.3% | 武汉 (12) |
|
||||
| 西北 | 6 | 6 | 0 | 2.3% | 西安 (6) |
|
||||
| 西南 | 7 | 7 | 0 | 2.7% | 重庆 (3) |
|
||||
| **TOTAL** | **259** | **261** | **-2** | 100% | — |
|
||||
|
||||
Brand keyword map (top 20 by 全国 count): BI 19 / Thermo 19 / Bio-Rad 11 / 赛默飞 8 / 安捷伦 7 / 蔡司 6 / Cytiva 6 / 伯乐 6 / 徕卡 6 / 赛多利斯 5 / Eppendorf 5 / Leica 5 / Beckman 4 / Merck 4 / Waters 4 / Azure 3 / Bruker 3 / Oxford Nanopore 3 / Agilent 3 / Sartorius 3.
|
||||
|
||||
**8-07 独有产品-代理映射 (from `_known_associations.md`):**
|
||||
|
||||
| 产品线 | 关联代理 / 中间方 | 关联客户 / 商机 |
|
||||
|---|---|---|
|
||||
| CelVivo (ClinoStar) | **济南成全生物科技 (曹沛起)** — 华北 + 山东 跨区重复 | 董慧群 (CelVivo 技术同事) — 8-07 hook 4 候选 |
|
||||
| FemtoBiomed (CellShot / PROLIVA) | **9X Bio (汇佰生物)** — 中间方 (0 hit in 259 dealer 表) | TriArm Therapeutics (翁靖傑 上海 CGT/CAR-T, 128 万 Phase1 / 8-10 至 8-14 现场 demo) |
|
||||
| 3Brain (HD-MEA) | 0 家代理命中 | 11+ end-customer dossiers (需要补 direct agent or sell direct) |
|
||||
| Cellink (BIO X) | 0 家代理命中 | (待补) |
|
||||
|
||||
**Data gap (regional filling rate):** 华东 营收 0/68 / 湖北 营收 0/19 / 华南 销售人数 0/62 — needs补 before next field visit. Documented at [`/sources/distributors-china-2026.md`](/sources/distributors-china-2026.md) §关键数据缺口.
|
||||
|
||||
**4-vendor break-out is deferred:** brand counts by region for CelVivo / 3Brain / Cellink / Femtobiomed are "待详细匹配" — the cross-match between dealer + vendor product line is not yet in the source page.
|
||||
**4-vendor break-out is partially resolved:** the 2026-08-07 `_known_associations.md` index identifies CelVivo → 济南成全 + FemtoBiomed → 9X Bio; 3Brain / Cellink direct agents are still 0 (open-question `distributors-3brain-cellink-zero-coverage`).
|
||||
|
||||
## CRM — active distributor profiles
|
||||
|
||||
From [`/sources/agents.md`](/sources/agents.md) (last sync 2026-07-28):
|
||||
From [`/sources/agents.md`](/sources/agents.md) (last sync 2026-07-28; 2026-08-07 `_known_associations.md` partial resolution):
|
||||
|
||||
| 姓名 | 角色 | 代理商品牌 | 主推产品 | 首次记录 | 状态 | Vault 路径 |
|
||||
| --- | --- | --- | --- | --- | --- | --- |
|
||||
@@ -261,7 +277,9 @@ From [`/sources/agents.md`](/sources/agents.md) (last sync 2026-07-28):
|
||||
|
||||
This is the only profile currently in the agents bucket. Robin was told about 董慧群 via WeChat DM on 2026-07-28; her role is to help push CelVivo products at the technical / demo / selection stage. Most fields are 待补 (agency name, region, phone, WeChat, customers, opportunities) — this is the only active open question in `/open-questions.md` (see `agent-dong-huiqun-celvivo`).
|
||||
|
||||
**Privacy rule (Robin 7-28):** `/sources/agents.md` and `/sources/distributors-china-2026.md` contain only base identity (name / role / vendor / region); sensitive fields (phone / WeChat / email / end-customer list / opportunity value) live only in the private Obsidian vault.
|
||||
**2026-08-07 partial resolution (Hermes hook 4):** 4 个经销商管理 Hook 升级 (`02-Clients/Agents/_known_associations.md` commit `4b237a82`) identifies **济南成全生物科技有限公司 (曹沛起)** as the only CelVivo ClinoStar-listed agent in the 259-dealer China map (华北 + 山东 跨区重复登记). Whether 董慧群 is 济南成全的技术同事 or another dealer is still unverified — tracked as commitment `dong-huiqun-ji-nan-chengquan-link` in `/commitments.md`. The same hook 4 file maps FemtoBiomed CellShot → 9X Bio (汇佰生物) → TriArm Therapeutics (翁靖傑 上海 CGT/CAR-T, 128 万 Phase1 / 8-10 至 8-14 现场 demo), and 3Brain / Cellink / FemtoBiomed direct agents → 0 in the 259 baseline (open-question `distributors-3brain-cellink-zero-coverage`).
|
||||
|
||||
**Privacy rule (Robin 7-28):** `/sources/agents.md` and `/sources/distributors-china-2026.md` contain only base identity (name / role / vendor / region); sensitive fields (phone / WeChat / email / end-customer list / opportunity value) live only in the private Obsidian vault. The 2026-08-07 `_known_associations.md` index adds the **product-line → agent → end-customer → opportunity** mapping chain — but does not break the privacy rule because sensitive fields remain in the private vault files.
|
||||
|
||||
## End-customer dossier set
|
||||
|
||||
|
||||
Reference in New Issue
Block a user